3-D Integrated Heterogeneous Intra-Chip Free-Space Optical Interconnect
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A Critical Evaluation of the Evidence Supporting the Practice of Behavioural Vision Therapy Brendan T
A Discussion and Analysis, in the context of current research to May 2016, of: A critical evaluation of the evidence supporting the practice of behavioural vision therapy Brendan T. Barrett (2009), Ophthal Physiol Opt 2009 29:4-25. Authors: Leonard J Press OD FCOVD FAAO Mark Overton B.App.Sci, MBA Stephen Leslie B Optom FACBO FCOVD Ophthalmic Medicines Prescriber The Australasian College of Behavioural Optometrists June 2016 COPYRIGHT ACBO 2016 ALL RIGHTS RESERVED Contents Introduction ................................................................................................................................ 3 Convergence Problems .............................................................................................................. 6 Accommodation ......................................................................................................................... 9 Strabismus & Amblyopia ......................................................................................................... 11 Yoked Prisms ........................................................................................................................... 17 Low Plus Prescriptions ............................................................................................................ 21 Near-Point Stress and Low Plus Prescriptions................................................................. 21 Plus near additions and Myopia ....................................................................................... 25 Mainstream Optometry and -
Integrating Free-Space Optics with CMOS
Microelectronics Journal 50 (2016) 66–75 Contents lists available at ScienceDirect Microelectronics Journal journal homepage: www.elsevier.com/locate/mejo Heterogeneous 3-D circuits: Integrating free-space optics with CMOS Ioannis Savidis a,n, Berkehan Ciftcioglu b, Jie Xu b, Jianyun Hu b, Manish Jain b, Rebecca Berman b, Jing Xue b, Peng Liu b, Duncan Moore b, Gary Wicks b, Michael Huang c, Hui Wu c, Eby G. Friedman c a Department of Electrical and Computer Engineering, Drexel University, Philadelphia, PA 19104, United States b Institute of Optics, University of Rochester, Rochester, NY 14627, United States c Department of Electrical and Computer Engineering, University of Rochester, Rochester, NY 14627, United States article info abstract Article history: A three-dimensional (3-D) integrated circuit combining free-space optical interconnects (FSOI) with Received 30 December 2014 CMOS devices has been developed. An overview of the combined optical and CMOS system is described. Received in revised form Experimental data and simulated results are provided. A 3-D integrated test circuit merging the free- 3 September 2015 space optical network with gallium arsenide based vertical cavity surface emitting lasers (VCSELs) and Accepted 13 October 2015 germanium based photodetectors has been experimentally tested. The prototype 3-D IC test circuit exhibits a 3.3 GHz bandwidth and a 5.1 mW total power consumption per link. The bandwidth is limited Keywords: due to the use of 5 GHz bandwidth commercial VCSELs and the large inductive impedance of the wir- 3-D IC ebonds attaching the VCSELs and photodetectors to the I/O pads. The design of transmitter circuits for the Free-space optical networks 3-D integrated free-space optical interconnect system is discussed, and simulated extrapolated results on Optical interconnects operating frequency and bandwidth are provided. -
Thesis May Never Have Been Completed
UvA-DARE (Digital Academic Repository) Digital Equipment Corporation (DEC): A case study of indecision, innovation and company failure Goodwin, D.T. Publication date 2016 Document Version Final published version Link to publication Citation for published version (APA): Goodwin, D. T. (2016). Digital Equipment Corporation (DEC): A case study of indecision, innovation and company failure. General rights It is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), other than for strictly personal, individual use, unless the work is under an open content license (like Creative Commons). Disclaimer/Complaints regulations If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: https://uba.uva.nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible. UvA-DARE is a service provided by the library of the University of Amsterdam (https://dare.uva.nl) Download date:26 Sep 2021 Digital Equipment Corporation (DEC) (DEC) Corporation Digital Equipment David Thomas David Goodwin Digital Equipment Corporation (DEC): A Case Study of Indecision, Innovation and Company Failure David Thomas Goodwin Digital Equipment Corporation (DEC): A Case Study of Indecision, Innovation and Company Failure David Thomas Goodwin 1 Digital Equipment Corporation (DEC): A Case Study of Indecision, Innovation and Company Failure ACADEMISCH PROEFSCHRIFT ter verkrijging van de graad van doctor aan de Universiteit van Amsterdam op gezag van de Rector Magnificus prof. -
V850/V850E GOFAST Floating Point Library Ver.1.1 Or Later
SUD-TT-0019-E CUSTOMER NOTIFICATION December 20, 2001 Yoshiro Miyaji, Group Manager Microcomputer Tool Group Sales Engineering Div. NEC Electron Devices NEC Corporation CP(K), O V850/V850E GOFAST Floating Point Library Ver.1.1 or Later [Supported Device/OS] IBM PC/AT Compatible Machine (WindowsTM Base) SPARCstation Family (SunOSTM/SolarisTM Base) Be sure to read this document before using the product. United States Software Corporation makes no warranty of any kind with regard to this material, including, but not limited to, the implied warranties of merchantability and fitness for a particular purpose. United States Software Corporation assumes no responsibility for any errors that may appear in this document. United States Software Corporation makes no commitment to update nor to keep current the information contained in this document. All rights reserved. No part of this document may be copied or reproduced in any form or by any means without the prior written consent of United States Software Corporation. Copyright 2001 by United States Software Corporation Unites States Software Corporation 7175 NW Evergreen Parkway, Suite 100 Hillsboro, Oregon 97124 Copyright (C) NEC Corporation 2001 - 2 - • V810 Family, V830 Family, V850 Series, V820, V821, V830, V831, V851, V853, V854, V850/SA1, V850/SB1, V850E/MS1, V850E/MA1, and EEPROM are trademarks of NEC Corporation. • Green Hills Software and MULTI are trademarks of Green Hills Software, Inc. • AutoCode, BSD, BSD/OS, BSD Lizard logo, Embedded Internet, Epilogue, ESp, FastJ, IxWorks, MATRIXX, pRISM, pRISM+, pSOS, RouterWare, SpOTLIGHT, Tornado, VxWorks, Wind, WindNavigator, Wind River Systems, Wind River Systems and Design, WindView, WinRouter and Xmath are registered trademarks (R) or service marks (SM) of Wind River Systems, Inc. -
Wolf-X-Ray-Brochure.Pdf
Dear Valued Wolf Customer Welcome to the 201 O Wolf X-ray Catalog. In response to the evolving needs of the Radiology community, Wolf has added many new innovative products to their line. While these new products all relate to radiology, many are not the first thing that comes to mind when you hear "Wolf" and the word "X-ray" only tells part of the tale of who we are. inSight llluminator -Trimline llluminators Our new PACS Adjustable Workstations allow the page 1 pages 5-10 radiologist to create a totally custom fitted viewing environment that can be changed at the touch of a button to accommodate different positions and different users. See page 29 for details. We have expanded our styles of positioners to include products for many medica! disciplines: Ortho, Pediatric, Veterinarian to name a few. And our new Utility Carts (page 41) nicely round Lead Eyewear out our already extensive line of Cassette and CR page 29 Aprons pages 25-28 Carts.Uitrasound users now have a choice of three gels and 3 instrument disinfectants that Wolf carries. Also in the "New" department is our addition of a complete line of CR tools ... plates, grids, screens and cassettes (page 36). Additionally, we feel this new catalog is better organized than ever before. Products are easy to find and logically grouped, and to make the catalog even more user friendly, for the most part the order PACS Workstations pages 21-24 of products in the catalog is repeated in our price Monitors page 20 list. And always remember, should you have any Wall Folding Desk page 47 questions, you can contact our knowledgeable customer service staff or one of our locally located Sales Reps or visit Wolf on the web at wolfxray.com. -
Oral History of Robert (Bob) W. Taylor
Oral History of Robert (Bob) W. Taylor Interviewed by: Paul McJones Recorded: October 10 - October 11, 2008 Woodside, California CHM Reference number: X5059.2009 © 2008 Computer History Museum Oral History of Robert (Bob) Taylor McJones: My name is Paul McJones. It’s October 10th, 2008. We’re going to conduct an oral history interview with Bob Taylor, and we have, behind the camera, Ken Beckman. Hello, Bob. Taylor: Hello, Paul. Hello, Ken [Bob’s friend and colleague at Xerox and DEC]. McJones: Bob, I thought it would be good to start at the beginning and have you tell us a little bit about growing up, your parents and early school and other experiences like that. Taylor: The very beginning? All right. This may be a little complicated. I was adopted when I was 28 days old in San Antonio, Texas. I was born in Dallas, so somehow or another, I don’t remember how, I moved, during my first 28 days of life, from Dallas to San Antonio. I was adopted from an orphanage, in effect, by a Methodist minister and his wife. They could not have any children of their own. They didn’t have RH negative things figured out in those days, so they adopted me. And during the first few years of my life I lived in small Texas towns where my father was a Methodist preacher. And then when I was about four, I guess, something like that, my father became a professor in a small Methodist college in San Antonio and we lived there for ten or eleven years. -
A Survey of RISC Architectures for Desktop, Server, and Embedded
D APPENDIX A Survey of RISC Architectures for Desktop, Server, and RISC: any computer announced aft er 1985. Embedded Computers Steven Przybylskic A Designer of the Stanford MIPS D.1 Introduction D-3 D.1 Introduction D-3 D.2 Addressing Modes and Instruction Formats D-5 D.3 Instructions: The MIPS Core Subset D-9 D.4 Instructions: Multimedia Extensions of the Desktop/Server RISCs D-16 D.5 Instructions: Digital Signal-Processing Extensions of the Embedded RISCs D-19 D.6 Instructions: Common Extensions to MIPS Core D-20 D.7 Instructions Unique to MIPS-64 D-25 D.8 Instructions Unique to Alpha D-27 D.9 Instructions Unique to SPARC v9 D-29 D.10 Instructions Unique to PowerPC D-32 D.11 Instructions Unique to PA-RISC 2.0 D-34 D.12 Instructions Unique to ARM D-36 D.13 Instructions Unique to Thumb D-38 D.14 Instructions Unique to SuperH D-39 D.15 Instructions Unique to M32R D-40 D.16 Instructions Unique to MIPS-16 D-40 D.17 Concluding Remarks D-43 D.1 Introduction We cover two groups of reduced instruction set computer (RISC) architectures in this appendix. Th e fi rst group is the desktop and server RISCs: ■ Digital Alpha ■ Hewlett-Packard PA-RISC ■ IBM and Motorola PowerPC ■ MIPS INC MIPS-64 ■ Sun Microsystems SPARC D-4 Appendix D A Survey of RISC Architectures Th e second group is the embedded RISCs: ■ Advanced RISC Machines ARM ■ Advanced RISC Machines Th umb ■ Hitachi SuperH ■ Mitsubishi M32R ■ MIPS INC MIPS-16 Alpha MIPS I PA-RISC 1.1 PowerPC SPARCv8 Date announced 1992 1986 1986 1993 1987 Instruction size (bits) 32 32 32 32 32 Address space -
Monosomy 3 Is Linked to Resistance to MEK Inhibitors in Uveal Melanoma
International Journal of Molecular Sciences Article Monosomy 3 Is Linked to Resistance to MEK Inhibitors in Uveal Melanoma Svenja Mergener 1,2,3 , Jens T. Siveke 2,3 and Samuel Peña-Llopis 1,2,3,* 1 Translational Genomics in Solid Tumors, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), University Hospital Essen, Hufelandstrasse 55, D-45147 Essen, Germany; [email protected] 2 Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), D-69120 Heidelberg, Germany; [email protected] 3 Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, Hufelandstrasse 55, D-45147 Essen, Germany * Correspondence: [email protected] Abstract: The use of MEK inhibitors in the therapy of uveal melanoma (UM) has been investigated widely but has failed to show benefits in clinical trials due to fast acquisition of resistance. In this study, we investigated a variety of therapeutic compounds in primary-derived uveal melanoma cell lines and found monosomy of chromosome 3 (M3) and mutations in BAP1 to be associated with higher resistance to MEK inhibition. However, reconstitution of BAP1 in a BAP1-deficient UM cell line was unable to restore sensitivity to MEK inhibition. We then compared UM tumors from The Cancer Genome Atlas (TCGA) with mutations in BAP1 with tumors with wild-type BAP1. Principal component analysis (PCA) clearly differentiated both groups of tumors, which displayed disparate overall and progression-free survival data. Further analysis provided insight into differential expression of genes involved in signaling pathways, suggesting that the downregulation Citation: Mergener, S.; Siveke, J.T.; of the eukaryotic translation initiation factor 2A (EIF2A) observed in UM tumors with BAP1 mutations Peña-Llopis, S.