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Stamp-V3 1..249 23 March 2016 Volume 23 Supplement 1 S1 Volume 23 Volume Supplement 1 P ages A1–A262 ages EUROPEAN JOURNAL OF HOSPITAL PHARMACY OF HOSPITAL JOURNAL EUROPEAN ABSTRACT BOOK 21st Congress of the EAHP 16-18 March 2016 Vienna, Austria March 2016 March Contents Volume 23 Supplement 1 | EJHP March 2016 Abstracts from the EAHP 2016 Congress A1 Clinical pharmacy A172 Other hospital pharmacy topics A104 Drug distribution A178 Pharmacokinetics and pharmacodynamics A118 Drug information and pharmacotherapy A195 Production and preparation A158 General management A214 Patient safety and risk management A167 International posters A250 Author index POSTER AWARD NOMINEES Presentations on Wednesday, 16 March, 14:00–15:30, Room 93 Time Poster number Poster nominee oral presentations Author 14:00 DD-021 Medicine supply chain of a central pharmacy: risk mapping F Charra shortage 14:10 PP-001 Contamination with cytotoxic drugs in the workplace – E Korczowska ESOP pilot study 14:20 PP-039 Double checking manipulations for complex and/or high A Alcobia Martins risk preparations 14:30 CP-055 The clinical pharmacist resolves medication related E Tudela-Lopez problems in cranio, maxillofacial and oral surgery patients 14:40 CP-085 The impact of pharmacist interventions on safety M Tovar Pozo and cost savings 14:50 CP-219 Effectiveness and safety of switching to dual antiretroviral J Luis Revuelta therapy in a treatment experienced HIV cohort 15:00 DD-027 Implementation and evaluation of an appointment based F J Alvarez Manceñido model for outpatients attended in a hospital pharmacy 15:10 PKP-031 Clinical pharmacokinetics of everolimus in lung M Martín Cerezuela transplantation: strategies of monitoring Presentations on Thursday, 17 March, 09:00–10:30, Room 93 Time Poster number Poster nominee oral presentations Author 09:00 PS-072 Does the computerised physician order entry system N Rouayroux reduce prescribing errors for inpatients? A before and after study 09:10 DI-008 Apps for paediatric dosing – an evaluation P Vonbach 09:20 PS-036 Improving pharmacological treatment: real time safety P A López audits 09:30 PS-046 Materiovigilance ex ante risk management A Dubromel 09:40 OHP-001 Health related quality of life and its associated factors F Alhomoud among South Asian and Middle Eastern patients with chronic diseases in the UK 09:50 CP-127 Inappropriate prescribing in elderly patients attending I Sánchez Navarro the emergency room 10:00 PS-049 Prospective detection of adverse drug reactions among A Lajoinie 2.263 hospitalised children over a 19month period: EREMI intermediate report Confidence from Evidence and Real World Experience Evidence from clinical and real world studies in SPAF1–3 and PE/DVT4,5 makes Xarelto® the world’s most prescribed NOAC,6 with over 18 million patients treated across all 7 indications worldwide.a,7,8 PE, pulmonary embolism; DVT, deep vein thrombosis; SPAF, stroke prevention in atrial fibrillation. NOAC, non-vitamin K antagonist oral anticoagulant. Calculation based on IMS Health MIDAS, Database: Monthly Sales December 2015. aIndications may vary by country. Xarelto 2.5 mg film-coated tablets (Refer to full SmPC before prescribing.) abnormal, urticaria, haemarthrosis, feeling unwell, increases in: bilirubin, blood alkaline with medicinal products affecting haemostasis; when neuraxial anaesthesia or ▼ This medicinal product is subject to additional monitoring. phosphatase, LDH, lipase, amylase, GGT. Rare: jaundice, muscle haemorrhage, localised spinal / epidural puncture is employed. For 15 mg / 20 mg only: specific dose oedema, bilirubin conjugated increased, vascular pseudoaneurysm (uncommon in recommendations apply for patients with moderate to severe renal impairment and Composition: Active ingredient: 2.5 mg rivaroxaban. Excipients: Microcrystalline prevention therapy in ACS following percutaneous intervention). Frequency not known: in case of DVT / PE-patients only if the patient’s assessed risk for bleeding outweighs cellulose, croscarmellose sodium, lactose monohydrate, hypromellose, sodium compartment syndrome or (acute) renal failure secondary to a bleeding. Post-marketing the risk for recurrent DVT / PE. In patients at risk of ulcerative gastrointestinal disease laurilsulfate, magnesium stearate, macrogol 3350, titanium dioxide (E171), iron observations (frequency no assessable): angioedema and allergic oedema, cholestasis prophylactic treatment may be considered. Although treatment with rivaroxaban oxide yellow (E172). Indication: Prevention of atherothrombotic events in adult and hepatitis (incl. hepatocellular injury), thrombocytopenia. does not require routine monitoring of exposure, rivaroxaban levels measured with patients after an acute coronary syndrome (ACS) with elevated cardiac biomarkers, a calibrated quantitative anti-Factor Xa assay may be useful in exceptional situations. co-administered with acetylsalicylic acid (ASA) alone or with ASA plus clopidogrel or Classification for supply: Medicinal product subject to medical prescription. Xarelto contains lactose. Undesirable effects: Common: anaemia, dizziness, ticlopidine. Contraindications: Hypersensitivity to the active substance or any of Marketing Authorisation Holder: Bayer Pharma AG, D-13342 Berlin, Germany headache, eye haemorrhage, hypotension, haematoma, epistaxis, haemoptysis, the excipients; active clinically significant bleeding; lesion or condition considered a Further information available from: [email protected] Version: EU/4 gingival bleeding, gastrointestinal tract haemorrhage, gastrointestinal and abdominal significant risk for major bleeding; concomitant treatment with any other anticoagulants pains, dyspepsia, nausea, constipation, diarrhoea, vomiting, pruritus, rash, ecchymosis, except under specific circumstances of switching anticoagulant therapy or when Xarelto 10 mg / 15 mg / 20 mg film-coated tablets (Refer to full SmPC before cutaneous and subcutaneous haemorrhage, pain in extremity, urogenital tract unfractionated heparin is given at doses necessary to maintain an open central venous prescribing.) ▼ This medicinal product is subject to additional monitoring. haemorrhage (menorrhagia very common in women < 55 years treated for DVT, PE or arterial catheter; concomitant treatment of ACS with antiplatelet therapy in patients or prevention of recurrence), renal impairment, fever, peripheral oedema, decreased with a prior stroke or a transient ischaemic attack (TIA); hepatic disease associated Composition: Active ingredient: 10 mg / 15 mg / 20 mg rivaroxaban. Excipients: general strength and energy, increase in transaminases, post-procedural haemorrhage, with coagulopathy and clinically relevant bleeding risk including cirrhotic patients with Microcrystalline cellulose, croscarmellose sodium, lactose monohydrate, hypromellose, contusion, wound secretion. Uncommon: thrombocythemia, allergic reaction, Child Pugh B and C; pregnancy and breast feeding. Warnings and Precautions: sodium laurilsulfate, magnesium stearate, macrogol 3350, titanium dioxide (E171), dermatitis allergic, cerebral and intracranial haemorrhage, syncope, tachycardia, Clinical surveillance in line with anticoagulation practice is recommended throughout iron oxide red (E172). Indications: 10 mg: Prevention of venous thromboembolism dry mouth, hepatic function abnormal, urticaria, haemarthrosis, feeling unwell, treatment. Xarelto should be discontinued if severe haemorrhage occurs. Increasing (VTE) in adult patients undergoing elective hip or knee replacement surgery. 15 mg increases in: bilirubin, blood alkaline phosphatase, LDH, lipase, amylase, GGT. Rare: age may increase haemorrhagic risk. Not recommended: in patients with severe renal / 20 mg: Prevention of stroke and systemic embolism in adult patients with non- jaundice, muscle haemorrhage, localised oedema, bilirubin conjugated increased, impairment (creatinine clearance <15 ml/min); in patients receiving concomitant valvular atrial fibrillation with one or more risk factors, such as congestive heart vascular pseudoaneurysm. Frequency not known: compartment syndrome or (acute) systemic treatment with strong concurrent CYP3A4- and P-gp-inhibitors, i.e. azole- failure, hypertension, age ≥ 75 years, diabetes mellitus, prior stroke or transient renal failure secondary to a bleeding. Post-marketing observations (frequency antimycotics or HIV protease inhibitors; in patients with increased bleeding risk; in ischaemic attack. Treatment of deep vein thrombosis (DVT) and pulmonary embolism not assessable): angioedema and allergic oedema, cholestasis and hepatitis (incl. patients receiving concomitant treatment with strong CYP3A4 inducers unless the (PE), and prevention of recurrent DVT and PE in adults. Special populations: Patients hepatocellular injury), thrombocytopenia. patient is closely observed for signs and symptoms of thrombosis; not recommended undergoing cardioversion: Xarelto can be initiated or continued in patients who may due to lack of data: treatment in combination with antiplatelet agents other than ASA require cardioversion. Contraindications: Hypersensitivity to the active substance Classification for supply: Medicinal product subject to medical prescription. and clopidogrel/ticlopidine; in patients below 18 years of age; in patients concomitantly or any of the excipients; active clinically significant bleeding; lesion or condition Marketing Authorisation Holder: Bayer Pharma AG, D-13342 Berlin, Germany treated with dronedarone. Use with caution: in conditions with increased risk of
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