STK4 Antibody Cat. No.: 23-365
STK4 Antibody
Immunoprecipitation analysis of 100ug extracts of HepG2 Immunohistochemistry of paraffin-embedded human cells using 3ug STK4 antibody (23-365). Western blot was esophagus using STK4 antibody (23-365) at dilution of performed from the immunoprecipitate using STK4 1:100 (40x lens). antibody (23-365) at a dilition of 1:1000.
Specifications
HOST SPECIES: Rabbit
SPECIES REACTIVITY: Human, Mouse, Rat
Recombinant fusion protein containing a sequence corresponding to amino acids 303-487 IMMUNOGEN: of human STK4 (NP_006273.1).
TESTED APPLICATIONS: IHC, IP, WB
WB: ,1:500 - 1:2000
APPLICATIONS: IHC: ,1:50 - 1:200
IP: ,1:20 - 1:50
October 2, 2021 1 https://www.prosci-inc.com/stk4-antibody-23-365.html POSITIVE CONTROL: 1) U-87MG
2) HepG2
3) HeLa
4) MCF-7
5) Mouse brain
6) Mouse lung
PREDICTED MOLECULAR Observed: 56kDa WEIGHT:
Properties
PURIFICATION: Affinity purification
CLONALITY: Polyclonal
ISOTYPE: IgG
CONJUGATE: Unconjugated
PHYSICAL STATE: Liquid
BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.
Additional Info
OFFICIAL SYMBOL: STK4
Serine/threonine-protein kinase 4, Mammalian STE20-like protein kinase 1, MST-1, STE20- like kinase MST1, Serine/threonine-protein kinase Krs-2, Serine/threonine-protein kinase 4 ALTERNATE NAMES: 37kDa subunit, MST1/N, Serine/threonine-protein kinase 4 18kDa subunit, MST1/C, STK4, KRS2, MST1
GENE ID: 6789
USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background and References
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and BACKGROUND: undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
October 2, 2021 2 https://www.prosci-inc.com/stk4-antibody-23-365.html ANTIBODIES FOR RESEARCH USE ONLY.
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October 2, 2021 3 https://www.prosci-inc.com/stk4-antibody-23-365.html