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ISSN 2225-0719 2021 Volume 9 Issue 1 January / February Journal of Clinical and Translational Hepatology Current Issue: Volume 9, Issue 1 JCTH Publication date: February 28, 2021 OWNED BY THE SECOND AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY PUBLISHED BY XIA & HE PUBLISHING INC. pISSN: 2225-0719; eISSN: 2310-8819 Frequency: Quarterly Launch date: September 28, 2013 (Volume 1, Issue 1) Aims and Scope Journal of Clinical and Translational Hepatology (JCTH, J Clin Transl Hepatol) Editors-in-Chief publishes high quality, peer-reviewed studies in the clinical and basic human Prof. Hong Ren health sciences of liver diseases. JCTH welcomes submissions of articles General Editor-in-Chief within its topical scope including: novel discoveries in clinical and basic hepa- The Second Affiliated Hospital of tology; liver disease mechanisms; novel techniques in research and manage- Chongqing ment of liver diseases; epidemiological/environmental factors of liver diseases; Medical University, China role of immune system function in liver diseases; acute and chronic hepatitis; Prof. George Y. Wu cirrhosis; genetic and metabolic liver diseases and their complications; hepa- Comprehensive Editor-in-Chief tobiliary diseases; liver cancer; drug metabolism; biliary disease; peritoneal tu- University of Connecticut Heath Center, USA berculosis. JCTH publishes various types of articles, including original article, Dr. Harry Hua-Xiang Xia review, short communication, systematic review, meta-analysis, case report, methodology article, letter to the editor, and editorial. Editor-in-Chief Guangdong Pharmaceutical University, China Indexing & Abstracting Managing Editors Huaidong Hu JCTH is now indexed in Science Citation Index Expanded (SCIE); PubMed; Chongqing, China PubMed Central; Scopus; Baidu Scholar; CNKI Scholar; Dimensions; EB- SCOhost; Google Scholar; Microsoft Academic; SafetyLit; ScienceOpen; Zhi Peng Scilit; Semantic Scholar; Wanfang Data; Web of Science; WorldCat Discov- Chongqing, China ery Services; Zetoc. Sandeep Kumar Karn Chongqing, China Open Access Executive Editor JCTH adopts open access publishing model, and all articles are distributed Hua He under the terms of the CC BY-NC 4.0 license (http://creativecommons.org/ Houston, USA licenses/by-nc/4.0/). Under this license, anyone may copy, distribute, or re- Technical Editor use these articles for non-commercial purposes, provided the original work is Huili Zhang properly cited. Manuscripts submitted for publication in an open access jour- nal are subject to the same rigorous peer-review and quality control as in Wuhan, China scholarly subscription journals. Contact Information Editorial Office Disclaimer Managing Editors: Dr. Huaidong Hu Dr. Zhi Peng All articles published in Xia & He journals represent the views and opinions of Dr. Sandeep Kumar Karn their authors, and not the views, opinions, or policies of the publisher, except Telephone: +86-23-6370 1383 where explicitly indicated. Xia & He Publishing shall not be held responsible Fax: +86-23-6370 1383 for the use of views and opinions expressed in the articles; use of any infor- E-mail: [email protected] mation in the articles shall not be considered an endorsement by Xia & He Postal Address: 74 Linjiang Road, Yuzhong Publishing of the products advertised. District, 400010 Chongqing, CHINA Publisher Xia & He Publishing Inc. Links Website: www.xiahepublishing.com Journal Home: https://www.xiahepublishing.com/journal/jcth [email protected] E-mail: Editorial Board: https://www.xiahepublishing.com/journal/jcth/editors Postal Address: 14090 Southwest Freeway, Archive: https://www.xiahepublishing.com/journal/jcth/archive Suite 300, Sugar Land, Texas, Instructions for Authors: https://www.xiahepublishing.com/journal/jcth/instruction 77478, USA Online Submission System: https://www.editorialmanager.com/jcth/default.aspx Associate Editors JCTH Viral Hepatitis, Cirrhosis and Liver Yu-Chen Fan Tehran, Iran Failure Department of Hepatology, Qilu Hospital of Shan- Xue-Feng Xia dong University Mohamed A Daw Key Laboratory for Reproduction and Genetics of Jinan, China Faculty of Medicine, University of Tripoli Guangdong Higher Education Institutes, Key Labo- Tripoli, Libya Kittichai Promrat ratory for Major Obstetric Diseases of Guangdong Province, Third Affiliated Hospital of Guangzhou Alpert Medical School of Brown University Xiao-Guang Dou Medical University; Department of Reproductive Providence, USA Medicine, Third Affiliated Hospital of Guangzhou Department of Infectious Diseases, Shengjing Hos- Medical University pital of China Medical University Ashwani Singal Guangzhou, China Shenyang, China Division of Gastroenterology and Hepatology, Uni- Jin-Lin Hou versity of South Dakota, Avera McKennan Univer- Surgery and Transplantation sity Health Center and Transplant Institute Hepatology Unit and Department of Infectious Dis- Sioux Falls, USA Michael Schilsky eases, Nanfang Hospital, Southern Medical Univer- Yale New Haven Transplantation Center, Yale sity Lai Wei University School of Medicine Guangzhou, China Hepatopancreatobiliary Center, Beijing Tsinghua New Haven, USA Jun-Qi Niu Changgung Hospital, School of Clinical Medicine, Tsinghua University Radiology Department of Hepatology, The First Hospital of Beijing, China Jilin University Li-Min Chen Changchun, China Ming-Hua Zheng Institute of Blood Transfusion, Chinese Academy of Medical Sciences, and Peking Union Medical Col- Nikolaos T. Pyrsopoulos NAFLD Research Center, Department of Hepatol- ogy, the First Affiliated Hospital of Wenzhou Medi- lege Division of Gastroenterology and Hepatology, Rut- cal University Chengdu, China gers New Jersey Medical School University Hospital Wenzhou, China Newark, USA Pathology Autoimmune and Cholestatic Liver Dis- Wendy Cao Arielle Rosenberg ease, DILI, Immunology New York University Langone Health University Paris Descartes New York, USA Paris, France John W. Birk UCONN Health, Division of Gastroenterology and Lan-Jing Zhang Qing-Feng Sun Hepatology Department of Pathology, Princeton Medical Center Department of Infectious Diseases, The Third Af- Farmington, USA Plainsboro, USA filiated Hospital to Wenzhou Medical College Timothy Billiar Wenzhou, China Liver Cancer and Oncology Department of Surgery, University of Pittsburgh Fu-Sheng Wang School of Medicine Douglas LaBrecque Pittsburgh, USA The Institute of Translational Hepatology, 302 Mili- Department of Internal Medicine, University of Iowa tary Hospital of China Iowa City, USA Beijing, China Aziz A. Chentoufi Immunology/HLA Department, National Reference Joseph Lim Da-Zhi Zhang Laboratory, Mohammed VI University of Health Sci- Section of Digestive Diseases/Yale Liver Center, ences Department of Infectious Diseases, The Second Yale University School of Medicine Casablanca, Morocco Affiliated Hospital of Chongqing Medical University New Haven, USA Chongqing, China Ji-Dong Jia Tawesak Tanwandee Alcohol and Nonalcoholic Fatty Liver Liver Research Center, Beijing Friendship Hospital, Division of Gastroenterology, Department of Medi- Disease Capital Medial University cine, Faculty of Medicine Siriraj Hospital, Mahidol Beijing, China Gyorgy Baffy University Bangkok, Thailand Department of Gastroenterology, VA Boston Health- Lun-Gen Lu care System, Harvard Medical School Department of Gastroenterology, Shanghai Gener- Man-Fung Yuen Boston, USA al Hospital, Shanghai Jiao Tong University School Department of Medicine, The University of Hong of Medicine Kong; Division of Gastroenterology and Hepatolo- Marko Duvnjak Shanghai, China gy, Department of Medicine, Queen Mary Hospital Department of Gastroenterology and Hepatology, Hong Kong Clinic of Internal medicine, Clinical Hospital Centre Farzin Roohvand “Sestre milosrdnice” Molecular Virology Department, Pasteur Institute Zagreb, Croatia of Iran Editorial Board Members JCTH Avin Aggarwal Ying Han Qing Mao George Tsoulfas Las Vegas, USA Xi'an, China Chongqing, China Thessaloniki, Greece Gianfranco D. Alpini Amr Shaaban Hanafy Matthew McMillin Vladimir Maximovich Temple, USA Zagazig, Egypt Austin, USA Tsyrkunov Leon D. Averbukh Kazuhiko Hayashi Nahum Mendez-Sanchez Grodno, Belarus Farmington, USA Nagoya, Japan Mexico City, Mexico Kang-Sheng Tu Mostafa El Awady Peng Hu Fan-Yin Meng Xi'an, China Giza, Egypt Chongqing, China Temple, USA David Victor Sina Aziz Jing Hua Ahmed Mesalam New York, USA Karachi, Pakistan Shanghai, China Cairo, Egypt Gen-Shu Wang Mahmoud Mohamed Yue-Hua Huang Albert D. Min Guangzhou, China Bahgat Guangzhou, China New York, USA Le-Yi Wang Cairo, Egypt Trana Hussaini Paul Naylor Urbana, USA Fernando Bessone Vancouver, Canada Detroit, USA Yu Jun Wong Rosario, Argentina Hartmut Jaeschke James S. Park Singapore Peter Buch Kansas City, USA New York, USA Yong-Ning Xin Farmington, USA Wasim Jafri María Teresa Pérez-Gracia Qingdao, China Chalermrat Bunchornta- Karachi, Pakistan Valéncia, Spain Ming Yan vakul Tatsuo Kanda Cyriac Abby Philips Jinan, China Bangkok, Thailand Tokyo, Japan Kochi, India Dong-Liang Yang Phunchai Charatcharoen- Ruhail Kohli Atoosa Rabiee Wuhan, China witthaya Baltimore, USA Washington, USA Li Yang Bangkok, Thailand John Koskinas Alok Ranjan Cincinnati, USA En-Qiang Chen Athens, Greece Washington, USA Tian Yang Chengdu, China Anastasios Koulaouzidis Sahaj Rathi Xi'an, China Po-Hung Chen Edinburgh, UK Vancouver, Canada Eric M. Yoshida Baltimore, USA Anand V Kulkarni Sammy Saab Vancouver, Canada Li Chen Hyderabad, India Los Angeles, USA Samar Samir Youssef Shanghai, China Ashish Kumar Behnam Saberi