Annual Report 2000 Affiliated with the University of Western Australia and Princess Margaret Hospital for Children
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TVW Telethon Institute for Child Health Research Annual Report 2000 Affiliated with The University of Western Australia and Princess Margaret Hospital for Children 100 Roberts Road, Subiaco, Western Australia 6008 ABN 86 009 278 755 Company Limited by Guarantee Telephone: (08) 9489 7777 Facsimile: (08) 94879 7700 Mission To improve the health of children through the development and application of research into the causes and prevention of ill-health and the maintenance of health Aims of the Institute • to conduct high quality research • to apply research findings to improve the health of children, adolescents and families • to teach the next generation of health researchers • to be an advocate for research and for children Early Origins of Childhood Disease: Research Programs at The TVW Telethon Institute for Child Health Research • Aboriginal Health • Asthma and Allergies • Birth Defects • Biostatistical Methods • Childhood Disabilities and Death • Child and Adolescent Mental Health • Infectious Diseases • Leukaemia and Cancer Research • Perinatal Epidemiology Contents Mission and Aims..................................................................................................................................................i Chairman’s Report................................................................................................................................................1 Board of Directors................................................................................................................................................3 Committees of the Board......................................................................................................................................4 Scientific Director’s Report..................................................................................................................................5 Chief Financial Officer’s Report........................................................................................................................10 New Building Opening ......................................................................................................................................11 Divisional Reports Cell Biology ..............................................................................................................................................13 Children’s Leukaemia and Cancer Research ............................................................................................18 Clinical Sciences........................................................................................................................................24 Molecular Biology ....................................................................................................................................32 Population Sciences ..................................................................................................................................38 Publications 2000................................................................................................................................................58 Research Grant Income ......................................................................................................................................63 Administrative and Corporate Services..............................................................................................................65 Income and Expenditure - Summary (2000)......................................................................................................66 Meningitis Centre ..............................................................................................................................................67 Friends of the Institute........................................................................................................................................68 Gifting Opportunities..........................................................................................................................................69 Donor List ......................................................................................................................................................70 Chairman's Report Kevin Campbell AM In many ways the year 2000 marked the coming of age for the TVW Telethon Institute for Child Health Research. This was symbolised in the celebrations surrounding the official opening of the new building by the Governor General, His Excellency Sir William Deane AC, KBE, on 1 September 2000. Symbolic too from a national perspective was the launch of the Kulunga Network, the Institute’s centre for indigenous child health research, as a curtain raiser to the official opening. Year 2000 will also be remembered as the year of the Sydney Olympics. As a nation, Australia revelled in the success of our sporting heroes, including the Para Olympians. Perhaps less obvious but equally as significant, the Institute was able to herald during the opening ceremony some outstanding national heroes in science and medical research. These included: Nobel Laureate, Professor Peter Doherty and the Chairman of the Health and Medical Research Strategic Review Committee, Mr Peter Wills AM. While unable to be there, elder statesman of Australian medical research and champion of the cause for national reconciliation, Professor Emeritus, Sir Gustav Nossal AC was part of the occasion nevertheless. These champions along with those of our own in Western Australia exemplified by our Director, Professor Fiona Stanley AC and her team of outstanding senior researchers, are inspirational to the nation. This Institute has robust and enduring research output. The measures of excellence in 2000 included nearly $4 million being awarded for peer reviewed national competitive grants including NHMRC grants; close to 100 recognised research publications; and the joint supervision of 40 or more postgraduate students. In addition commercial and government research contracts attracted a further $3.5 million. This is an outstanding achievement for a research institute that has been in operation for just over 10 years. The move to the new building in March was the culmination of years of grant seeking, fundraising, consultation and dedicated planning by our Director, Professor Fiona Stanley and her staff, the Board of the Institute and the many donors and supporters. We remain indebted to the Commonwealth Government and the State Government for their combined investment in the long-term interests of child health research in Western Australia through the building grant of $22.5 million. We recognise too that the example had been set earlier by the business community and the broader community in their generous support for the “Give Every Child A Chance Campaign”. Through the pledged support of Telethon, Australian Capital Equity, Wesfarmers, and over 200 Australian based business houses and private donors, by Year 1 2000 over $10 million of the pledged $11.8 million Finally may I once again pay tribute to the members for a campaign of 5 years had been received. Most of of the Board of the Institute. The long-standing the remaining pledges will be honoured in 2001. members, Professor Lou Landau AO and Mr Harvey Coates continue to provide leadership and vision. I On behalf of the Board I would like to thank the raft was pleased during 2000 to welcome new members of volunteers who support the many not for profit, to the Board and these appointments were ratified at non government charitable organisations dedicated the Annual General Meeting in May. They were: Mr to raising funds for research into the many diseases Keith Jones, Managing Partner of Deloittes; Ms that afflict our children. Rebecca Maslen-Stannage, Partner at Freehills; and I would like to single out the Variety Club of Mr Michael Daube, Chief Executive Officer of the Western Australia. As a community based charitable Cancer Foundation. I am also grateful that Dr organisation which raises funds solely for the benefit Graham Mitchell AO, Chief Scientist of Victoria, of children, the Variety Club has during the last was able to participate at Board meetings via decade, raised nearly a million dollars in support of teleconference, and has now accepted a formal child health research, through the sponsorship of the position on the Board. During the year too, we Director’s professorial Chair. farewelled Mrs Rae Willis as President of the Friends, and I was able to welcome the incoming I would like to thank our long standing auditors, President, Mrs Marilyn Stewart, as a member of the KPMG, who for many years have provided for us an Board ex officio. outstanding service and have been great supporters of the work of the Institute. I wish to acknowledge Each of the Board members is actively involved in work undertaken for the Institute by solicitors the Board committees which play such an important Clayton Utz and also Freehills. role in the governance of the Institute. I am proud to be associated with such outstanding professional people who devote so much of their time to the benefit of the Institute, and who share a vision of healthy children and a healthy community. As a Board we are proud that we have been able to contribute to the coming of age, and we look forward to the growth and development of the Institute and its people in the twenty first century. Kevin Campbell AM 2 Board of Directors Mr Kevin Campbell AM Mr Harvey Coates Chairman, TVW Telethon Institute for MBBS MS Diplomate American Board Child Health