Anti-DCAF7 monoclonal antibody (DCABH-201719) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description This encodes a with multiple WD40 repeats which facilitate protein-protein interactions and thereby enable the assembly of multiprotein complexes. This protein has been shown to function as a scaffold protein for protein complexes involved in kinase signaling. This highly conserved gene is present in eukaryotic plants, fungi, and animals. The ortholog of this gene was first identified in plants as a key regulator of anthocyanin biosynthesis and flower pigmentation. Alternative splicing results in multiple transcript variants.

Immunogen A synthetic peptide of human WDR68 is used for rabbit immunization.

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Protein A

Conjugate Unconjugated

Applications WB, ELISA

Size 1 mg

Buffer In 1x PBS, pH 7.4

Preservative None

Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

GENE INFORMATION

Gene Name DCAF7 DDB1 and CUL4 associated factor 7 [ Homo sapiens (human) ]

Official Symbol DCAF7

Synonyms DCAF7; DDB1 and CUL4 associated factor 7; AN11; HAN11; WDR68; SWAN-1; DDB1- and CUL4-associated factor 7; human anthocyanin; WD repeat-containing protein 68; WD repeat- containing protein An11 homolog; seven-WD-repeat protein of the AN11 family-1;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Gene ID 10238

Protein Refseq NP_005819

UniProt ID P61962

Chromosome Location 17q23.3

Pathway TNF-alpha/NF-kB Signaling Pathway;

Function protein binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved