Appointment of: Programme leaders for the UK Research Institute Contents

The UK DRI will become a scientific hotbed 3 About the UK Dementia and one of the most exciting places for Research Institute breakthrough innovations, so we need 4 Strategic vision ambitious scientists at all career stages and 6 About the centres a mix of expertise. 8 Programme leader profile - UK DRI Professor Professor Bart De Strooper, UK DRI Director

12 Programme leader profile - UK DRI Fellow

16 How to apply

3 About the UK Dementia Research Institute

The UK Dementia Research • accelerate the pace of discovery Council took the reins as leader Institute (UK DRI) is a joint £250 research to identify new targets of the institute in November 2015 million investment into dementia for drug development with a £150 million commitment. research led by the Medical Alzheimer’s Society and Research Council (MRC) alongside • develop new approaches for Alzheimer’s Research UK joined founding charity partners delivering effective clinical trials to as founding partners in early 2016, the Alzheimer’s Society and targeted patient groups contributing an additional £100 Alzheimer’s Research UK. million to the initiative. • attract new partnerships with The UK DRI will deliver a the biopharmaceutical sector step-change in the scientific to develop new therapeutics and Locations understanding of dementia, diagnostics generating new targets for drug With its headquarters at University development, reinvigorating the • develop and promote strategies College, London (UCL), the institute therapeutic pipeline and helping for interventions that prevent the comprised of centres across six to transform care. development or progression of UK universities: the University of dementia Cambridge, Cardiff University, the The new national institute will cover University of Edinburgh, Imperial dementia across the research • provide new insights and College London, King’s College spectrum, spanning Alzheimer’s technology-based approaches to London and UCL. disease, Parkinson’s disease, delivering more effective care and , vascular support to people with dementia dementia, Huntington’s disease and their carers. From summer 2017, the UK DRI and beyond. is seeking up to 18 programme leaders at the professor and Bringing together over 400 world- Origins fellowship level under a first leading scientists in biomedical, phase of recruitment to develop care and translational dementia The Prime Minister’s Challenge and lead a programme of research, the institute will carry on Dementia 2020 set out a clear research within and out a rich, varied and integrated target for research to deliver the complementing the portfolio of programme of research. The first effective treatments and the UK DRI. The programmes institute will form a vibrant and disease modifying therapies for will need to fit scientifically to the interactive community, centred on dementia by 2025 and called for selected centre, which will be the working on around the establishment of a national direct employer 50 five-year research programmes Dementia Research Institute by across the UK in order to: 2020. The Medical Research 4 Strategic vision

UK DRI Director Professor Bart UK DRI centres and research the institute, from different fields De Strooper has set an ambitious groups will naturally specialise across biomedical and translational vision for the institute, identifying in certain research areas, but research. Together this diverse the gap in our knowledge of how the institute is designed to be range of expertise will fill and enrich the healthy brain functions and opportunistic and grasp all good knowledge gaps in . what leads to its degeneration. The ideas that could take us further UK DRI will achieve this by focusing in fighting the biggest health At the heart of the UK DRI is on the biological mechanisms challenge of our generation. innovation. A creative ethos will underpinning dementia. run throughout the institute. A Researchers at the UK DRI will significant part of the budget will be embrace novel technologies and Creativity and collaboration used to expand and implement the interdisciplinary approaches in new ideas generated by everyone order to build new knowledge and The UK DRI will help build the working at the UK DRI, taking understanding that will lead to next generation of dementia account of future partnership new treatments. researchers, by attracting new opportunities. researchers into the field and Research will initially focus on providing access to interdisciplinary The institute will also promote developing better models of training and cutting-edge collaborative working, both across disease and translating research resources. The institute will set the institute and also plugging into findings into new diagnostics and a dynamic pace to establish a dementia initiatives across the treatments and, in the longer term, vibrant, ambitious and interactive UK and beyond. The institute is cures. A care research strand will neuroscience community of initially looking to foster strong industry be incorporated as the institute 400 scientists. It will build on the connections so that discoveries develops, as will research seeking strong dementias research base made in the laboratory can lead to develop new approaches that already exists in the UK. to new treatments for people with to prevention. Top talent and rising stars from dementia as swiftly as possible. all over the world will come to Building a strategy for international excellence

The director and associate directors are working together to establish the institute’s research priorities. The strategy will be published on Our vision for the institute is to identify the our website later in 2017. gap in our knowledge of how the healthy The first phase of the UK DRI brain functions and what leads to its establishment is focused on basic biomedical research. However, it’s degeneration. important that while the UK DRI looks for new medical treatments Professor Bart De Strooper, UK DRI Director for all dementias, it also ensures that those living with dementias and their carers can lead the fullest lives possible. That’s why research into dementia care will be integrated into the research strategy in 2018. 6 About the UK DRI centres

Having centres located across gene expression and biological mechanisms of synapse, the UK allows the UK DRI to bring pathways in single cells related and circuit level researchers together for shared to the progression of Alzheimer’s dysfunction leading to cognitive scientific inspiration, while making disease; new biomarkers to decline; macroglial and microglial the most of local cutting-edge tools monitor disease progression; roles in neuroprotection and and infrastructure. Each centre deficits in axonal transport in early ; the biology of is led by an associate director, neurodegeneration; Wnt signalling cerebrovascular, blood-brain-barrer contributing towards achieving the in synapses to discover new targets and metabolic dysfunction institute’s shared vision. for future dementia therapies. in neurodegenerative disease. The six UK DRI centres are located at: , Cardiff UK DRI at the University of UK DRI at King’s College University, University of Edinburgh, Edinburgh London , King’s College London and University College, London (UCL), which UK DRI at the University of UK DRI at King’s College London also operates as the Edinburgh will be located on the will be located in the newly built institute’s headquarters. BioQuarter, Edinburgh’s new Maurice Wohl Clinical Neuroscience multidisciplinary research institute Institute on the Denmark Hill and teaching hospital with access Campus which houses the UK DRI at UCL to superb multimodal neuroimaging Nikon Centre of Excellence for and clinical research facilities. Neuroscience Imaging. Research from UK DRI at UCL will cover the journey from the patient The research team lead by Led by Professor Chris Shaw, the to the laboratory and back to the Professor Giles Hardingham will team will focus on the misfolding patient with improved diagnosis, examine the complex interactions and aggregation of the protein TDP- biomarkers and candidate between cells of the brain, immune 43, aiming to uncover fundamental therapies. Led by Professor Bart De system and blood vessels that mechanism common to several Strooper, UK DRI Director, the team make up the ‘neurogliovascular protein misfolding disorders that will address the key unanswered unit’. The team brings together can inform the development of mechanistic questions that link strengths in metabolism, therapies for multiple forms genetic and lifecourse factors to inflammation, blood vessel of dementia. dysfunction in molecular pathways, biology and stem cell medicine in cells and in neural systems to explore how interactions at the Key science areas at UK DRI during the progression of neurogliovascular unit control the at King’s College London dementias. trajectory of neurodegenerative include: Frontotemporal dementia diseases leading to dementia. and amyotrophic lateral sclerosis; UCL is the headquarters of UK DRI. Parkinson’s and Dementia with Key science areas at UK DRI Lewy Bodies; Vascular dementia, Key science areas at UK DRI at the University of Edinburgh including Diabetes and Metabolic Mechanistic at UCL include: include: Cellular interplay Syndrome; mechanisms of understanding of dysfunction maintaining brain homeostasis and synaptopathy. in cells and neural systems; and its disruption in dementia; 7

UK DRI at Cardiff University the greatest potential to prevent campus Hammersmith, London, dementia. Led by Professor in the Sir Michael Uren Biomedical UK DRI at Cardiff University will be Giovanna Mallucci, the team Engineering Research Hub due to located in the Hadyn Ellis building will use cellular and molecular be completed in 2019, alongside on the Innovation campus, with approaches to better characterise Imperial’s translation and access to state of the art facilities these important processes with innovation ‘I-HUB’. within the Cardiff University a strong emphasis on identifying Dementia Research Network. molecular targets that can be Led by Professor Paul Matthews, translated into new the research team will bring novel, Centre Director, Professor Julie dementia treatments. cutting edge approaches and Williams and colleagues at Cardiff research tools to the study of University have discovered over Key science areas at UK dementia to discover new disease 27 risk genes for dementia which DRI at the University of mechanisms and therapeutic implicate the innate immune Cambridge include: Molecular targets. They will initially focus on response in determining a person’s and cell biological approaches the earliest pre-symptomatic stages susceptibility to developing to understanding disease of Alzheimer’s disease, addressing Alzheimer’s disease. Building mechanisms, focusing on what determines the transition on their world-class expertise in proteostasis, translational control to neurodegeneration, but will genetics and immunology, the UK at the synapse, myelin/axon investigate mechanisms that are DRI at Cardiff University will use interactions in neuronal health likely shared across many of these discoveries as the starting and disease, the biomechanics of the dementias. point for understanding disease brain ageing and its role in disease mechanisms and producing processes and therapy, with an Key science areas at UK DRI new therapies. emphasis on inter-disciplinary at Imperial College London science, including biophysics include: Neuroinflammation Key science areas at Cardiff and chemistry and molecular and neurodegeneration; University include: Disease neuroscience. epigenomic influences on risks mechanisms building on genetic and progression of dementia; evidence including; risk profiles; roles of the microbiome in pathways and networks associated UK DRI at Imperial College cognition and neurodegeneration; with Alzheimer’s disease, London circadian neurobiology and Huntington(s) diseases and other mechanisms of neurodegeneration; dementias; specific focus will be UK DRI at Imperial College London neurotechnologies for targeted on immunity, lipid processing, will be located at the White City neuronal and glial modulation. endocytosis, DNA repair mechanisms and ApoE.

UK DRI at the University of Cambridge

UK DRI at the University of Cambridge will based in the newly refurbished Island Research Building on the Cambridge Biomedical Campus.

The centre will focus on the mechanistic processes involved in the earliest stages of neurodegenerative disease to Left to right: Paul Matthews (Imperial), Giovanna Mallucci (Cambridge), Bart De Strooper identify therapeutic targets with (UCL), Giles Hardingham (Edinburgh), Julie Williams (Cardiff), Chris Shaw (KCL) 8 Programme leader profile: UK DRI Professor

Summary details Detailed job description programme, including purchasing and managing the effective use Institute: Overall purpose: of capital equipment. UK Dementia Research Institute (UK DRI) To direct an internationally • To publish the work of the competitive research programme programme in appropriate Centre: within the UK Dementia Research internationally visible scientific Open across six UK DRI centres Institute (UK DRI) relevant to the journals and other relevant area of neurodegeneration, with media. Job title: the ultimate aim of improving Programme leader (Professor) human health. You will draw on the • To present the results of knowledge and expertise of other the research at national and Salary range: colleagues both within and outside international meetings and A competitive salary will of the UK DRI through collaborative conferences. be available inputs and team working. The UK DRI is looking to transform the • To secure and manage external Grade: field of dementias research and funding from grant-giving bodies See UK DRI centre’s website welcomes scientists from and industries to supplement UK for details all disciplines. DRI programme funding.

Contract type (eg Open/Fixed Main duties: • To develop interactions with term): industry and translate the Open ended • To develop and lead a results of research into useful programme of research within new approaches or treatments Hours (e.g. full or part time): and complementing the portfolio that can be taken up by the Will vary according to UK of the UK DRI appropriate to the appropriate industry, ultimately to DRI centre selected centre. improve human health.

Programme funding: • To recruit, train, line manage • To ensure that any intellectual Up to £3 million provided over and develop research team property is protected according five years members. to UK DRI Ltd policy for the benefit of the UK DRI, the UK • To manage the financial and economy and patients equipment resources of the and carers. 9

• To contribute to the UK DRI’s media enquiries. Working with the areas of training, enhancing engagement with patients and HEI’s press office and the UK public awareness of scientific the broader public, in particular DRI to ensure that achievements issues, interaction with academic to communicate the excitement are widely publicised through all and health service providers and of research to the public in an suitable media. commercial exploitation where accessible way and to help raise appropriate. the profile of the UK DRI. • Working as a scientific leader within the UK DRI institute and • Maintaining a broad balanced • To respond to the UK DRI Board promoting this concept within the and informed perspective of as required by the director. UKDI as a single institute. current scientific issues especially those pertaining directly to the Key responsibilities: • Determining and managing the field of research. resource requirements to sustain • Research leadership of a group the programme, including the • Contributing to scientific progress of research scientists, comprising staffing structure required for in the field as a whole by, for postdoctoral fellows, PhD taking forward the programme of example, membership of expert students and technical research to success. committees, editing specialist support staff. journals and refereeing funding • With operational support, applications. • Planning the scientific direction maintain oversight and of the research programme responsibility for the recruitment, • Contributing to public aimed at key questions within management, training and career communications initiatives in the overall scientific remit of development of group members, order to facilitate greater the UK DRI; being accountable including line management public engagement with science for presenting the programme and performance management, and specifically, contributing to for peer review, as part of the in accordance with the UK DRI engagement with patients and institute’s scientific assessment, and the host HEI’s policies their carers. in accordance with the funders’ and procedures. procedures. • Ensuring all research within • Contributing to the harmonious the programme is conducted in • Contributing to the overall and successful running of the UK accordance with good practice scientific mission of the UK DRI DRI and HEI and helping and in compliance with UK and the HEI. to ensure that the research DRI and HEI policies and legal programme team does the same. requirements. • Directing the activities of the Actively maintaining and research group by supervising managing the relationship and Working relationships: some projects personally and interface with the host HEI. overseeing projects delegated Within the UK DRI you will report to to group members. You will be • Generating and managing the Centre Associate Director and, expected to provide the collaborations both within the in turn, to the Director of UK DRI. intellectual energy and centre, the UK DRI, the host HEI independent thinking necessary and with external establishments. As an independent Programme to lead and deliver a programme Leader you will interact with of cutting edge research and to • Identifying and acting on scientists and support staff at all shape the overall aims and opportunities for the creation levels within the centre and the UK success of the group. of intellectual property and DRI, the host HEI and externally cooperating in patent protection with senior personnel in the • Disseminating the research and in exploitation according to national and international research outputs from the group by UK DRI policy. community, including research publication of results, institutes, funding bodies and presentations at scientific • Contributing to the funders’ commercial companies. meetings and responding to and the HEI’s commitment in 10

Equality & Diversity Job descriptions should be Person requirements reviewed on a regular basis and at The UK DRI and the HEI value the annual appraisal. Any changes Education / qualifications / the diverse skills and experience should be made and agreed training required of employees and are committed between the post holder and to achieving equality of treatment their manager. Essential: for all. Our objectives are that • PhD or equivalent. all individuals shall have equal The above lists are not exhaustive opportunities for employment and and the job holder is required to • Has been recognised for quality advancement on the basis of their undertake such duties as may of research by national and/or skills, aptitudes and abilities. The reasonably be requested within the international awarding bodies. UK DRI and the HEI are committed scope of the post. All employees to the engagement and retention are required to act professionally, Desirable: of the best possible talent and co-operatively and flexibly in line • Bringing novel approaches to creating an environment that with the requirements of the post, and insights to the field of encourages excellence in scientific the UK DRI and the host HEI. neurodegeneration research. research through good equalities and diversity leadership Previous work experience and management. required

Corporate/Local Essential: responsibilities & requirements • Proven scientific leadership.

The job holder must at all times Knowledge and experience carry out their responsibilities with due regard to the UK DRI and Applicants should have a proven host HEI’s: track record of internationally competitive scientific research • Code of Conduct relevant to the UK DRI core programme. • Equality and Diversity policy Essential: • Health and Safety policy • Demonstrates that the proposed research interfaces • Data Protection and and complements the present Security policy portfolio and future science strategy of the centre and the UK DRI as a whole. 11

• Experience of planning and • Experience in identifying and developing projects or capitalising on opportunities for programmes of research. the creation of intellectual property and the exploitation of • Demonstrates scientific commercial potential; cooperating innovation, enabling apparently in patent protection and other intractable problems to mechanisms used by home Personal skills / behaviours / be successfully tackled and institute to protect qualities overcome. intellectual property. Essential: • Strong record of publications • Experience of managing • Proactive and creative in high impact journals, with resources (funding, equipment independent thinker. emphasis on quality. and people). • Ability to lead people within a • Proven experience in presenting • Experience in recruiting, training research programme group in an and defending the results of and line managing PhD students inspiring manner, building them research. and postdoctoral scientists. into an excellent research team.

• Record of being awarded • Experience of communicating • Strong skills in working with staff competitive grants. and engaging with a wide range of different levels, including non- of stakeholders including the science specialists, across the Desirable: press, the public, including home institute. • Experience of having influenced patients and their carers and knowledge or wider practice in schools. • Ability to take critical and previous research field. timely decisions.

• Experience of providing the • Tenacity and resilience. critical thinking required to create and run an independent research • Good communicator. programme. Additional information • Experience of leading successful projects independently. We are looking for a dynamic, dedicated, individual with a flair • Experience in building, for innovation who will contribute strengthening and sustaining across the UK DRI as well as successful collaborations both within the host centre, and who is within the home institute and appreciative of the importance of externally, influencing outcomes hard work. and/or direction.

12 Programme leader profile: UK DRI Fellow

Summary details Detailed job description • To manage the financial and equipment resources of the Institute: Overall purpose: programme, including UK Dementia Research Institute purchasing and managing (UK DRI) To lead an internationally the effective use of competitive research programme capital equipment. Centre: within the UK Dementia Research Open across six UK DRI centres Institute (UK DRI) relevant to the • To publish the work of the area of neurodegeneration, with programme in appropriate Job title: the ultimate aim of improving internationally visible scientific Programme Leader (Fellow) human health. You will draw on the journals and other knowledge and expertise of other relevant media. Salary range: colleagues both within and outside A competitive salary will of the UK DRI through collaborative • To present the results of be available inputs and team working. The UK the research at national and DRI is looking to transform the international meetings Grade: field of dementias research and and conferences. See UK DRI centre’s website welcomes scientists from for details all disciplines. • To secure and manage external funding from grant-giving bodies Contract type (e.g. Open/Fixed Main duties: and industries to supplement UK term): DRI programme funding. Open ended • To develop and lead independently a programme • To develop interactions with Hours (eg full or part time): of research within and industry and translate the results Will vary according to UK complementing the portfolio of research into useful new DRI centre of the UK DRI appropriate to the approaches or treatments that selected centre. can be taken up by the Programme funding: appropriate industry, ultimately to Up to £1.5 million provided over • To recruit, train, line manage improve human health. five years and develop members of the research team. • To ensure that any intellectual property is protected according to UK DRI Ltd policy, for the 13

benefit of the UK DRI, the UK • Contributing to the overall • Determining and managing the economy and patients scientific mission of the UK DRI resource requirements to sustain and carers. and the HEI. the programme, including the staffing structure required for • To contribute to the UK DRI’s • Directing the activities of the taking forward the programme of engagement with patients and research group by supervising research to success. the broader public, in particular some projects personally and to communicate the excitement overseeing projects delegated • With operational support, of research to the public in an to group members. You will be maintain oversight and accessible way and to help raise expected to provide the responsibility for the recruitment, the profile of the UK DRI. intellectual energy and management, training and career independent thinking necessary development of group members, • To respond to the UK DRI Board to lead and deliver a programme including line management as required by the Director. of cutting edge research and to and performance management, shape the overall aims and in accordance with the UK DRI Key responsibilities: success of the group. and the host HEI’s policies and procedures. • Research leadership of a group • Disseminating the research of research scientists, comprising outputs from the group by • Contributing to the harmonious postdoctoral fellows, PhD publication of results, and successful running of the UK students and technical presentations at scientific DRI and HEI and helping support staff. meetings and responding to to ensure that the research media enquiries. Working with programme team does the same. • Planning the scientific direction HEI’s press office and the UK Actively maintaining and of the research programme DRI to ensure that achievements managing the relationship and aimed at key questions within are widely publicised through all interface with the host HEI. the overall scientific remit of suitable media. the UK DRI; being accountable • Generating and managing for presenting the programme • Working as a scientific leader collaborations both within the for peer review as part of the within the UKDI as a single centre, the UK DRI, the host HEI institute’s scientific assessment, institute and promoting this and with external establishments. in accordance with the funders’ concept within the group and procedures. more widely. • Identifying and acting on opportunities for the creation of intellectual property and 14

cooperating in patent protection with senior personnel in the undertake such duties as may and in exploitation according to national and international research reasonably be requested within the UK DRI policy. community, including research scope of the post. All employees institutes, funding bodies and are required to act professionally, • Contributing to the funders’ commercial companies. co-operatively and flexibly in line and the HEI’s commitment in with the requirements of the post, the areas of training, enhancing Equality & Diversity the UK DRI and the host HEI. public awareness of scientific issues, interaction with academic The UK DRI and the HEI value and health service providers and the diverse skills and experience Person requirements commercial exploitation where of employees and are committed appropriate. to achieving equality of treatment Education / qualifications / for all. Our objectives are that training required • Maintaining a broad balanced all individuals shall have equal and informed perspective of opportunities for employment and Essential: current scientific issues especially advancement on the basis of their • PhD or equivalent, excellent those pertaining directly to the skills, aptitudes and abilities. The research training. field of research. UK DRI and the HEI are committed to the engagement and retention Desirable: • Contributing to scientific progress of the best possible talent and • Has been recognised for quality in the field as a whole by, for to creating an environment that of research by national and/or example, membership of expert encourages excellence in scientific international awarding bodies. committees, editing specialist research through good equalities journals and refereeing funding and diversity leadership Previous work experience applications. and management. required

• Contributing to public Corporate/Local Essential: communications initiatives in responsibilities & requirements • Substantial postdoctoral order to facilitate greater experience. public engagement with science The job holder must at all times and specifically, contributing to carry out their responsibilities with • Wide knowledge of the engagement with patients and due regard to the UK DRI and techniques and methodology their carers. host HEI’s: required to carry out the proposed research relevant to • Ensuring all research within • Code of Conduct neurodegeneration. the programme is conducted in accordance with good practice • Equality and Diversity policy Desirable: and in compliance with UK • Experience with supervision of DRI and HEI policies and legal • Health and Safety policy staff and/or students. requirements. • Data Protection and Security Knowledge and experience: Working relationships: policy Applicants should have a proven Within the UK DRI you will report to Job descriptions should be track record of internationally the Centre Associate Director and, reviewed on a regular basis and at competitive scientific research in turn, to the Director of UK DRI. the annual appraisal. Any changes relevant to the UK DRI should be made and agreed core programme. As an independent Programme between the post holder and Leader you will interact with their manager. Essential: scientists and support staff at all • Demonstrates that the levels within the centre and the UK The above lists are not exhaustive proposed research interfaces and DRI, the host HEI and externally and the job holder is required to complements the present 15

portfolio and future science • Experience of or clear potential Personal skills / behaviours / strategy of the centre and the UK to lead successful projects qualities DRI as a whole. independently. Essential: • Experience of planning and • Experience in building, • Proactive and creative developing projects or strengthening and sustaining independent thinker. programmes of research. successful collaborations both within the home institute and • Evidence of potential to • Demonstrates scientific externally, influencing outcomes lead people within a research innovation, enabling apparently and/or direction. programme group in an inspiring intractable problems to be manner, building them into an successfully tackled • Experience in identifying and excellent research team. and overcome. capitalising on opportunities for the creation of intellectual • Strong skills in working with staff • Strong record of publications in property and the exploitation of of different levels, including non- high impact journals, with commercial potential; science specialists, across the emphasis on quality. cooperating in patent protection home institute. and other mechanisms used • Proven experience in presenting by home institute to protect • Ability to take critical and and defending the results intellectual property. timely decisions. of research. • Experience of managing • Tenacity and resilience. • Record of being awarded resources (funding, equipment competitive grants. and people). Experience • Good communicator. in recruiting, training and line • Excellent scientific reputation. managing of staff or students. Additional information

Desirable: • Experience of communicating We are looking for a dynamic, • Experience of having contributed and engaging with a wide range dedicated, individual with a flair to knowledge or wider practice in of stakeholders including the for innovation who will contribute the field. press, the public, including across the UK DRI as well as patients and their carers within the host centre, and who is • Experience of providing the and schools. appreciative of the importance of critical thinking required to create hard work. and run an independent research programme.

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How to apply

We encourage you to contact the Please click on the links below to director of your preferred centre for find out more from your preferred an informal discussion. UK DRI centre.

Applicants should choose one Should you have any questions on centre based on best science any aspects of applying, please and location fit, submitting one contact [email protected]. application to UK DRI as a whole ac.uk via your preferred centre. Your UK DRI at University College location preference will be strongly London considered at selection stage. UK DRI at the University of When applying you will need to Cambridge provide: • your CV with full publication list UK DRI at Cardiff University • your motivation for application UK DRI at the University of (200 words) Edinburgh • a research statement including a half-A4 page vision and UK DRI at Imperial College London objectives and 1.5 pages of your experimental plans UK DRI at King’s College London • names of three personal referees • your preferred location.