Autumn 2020 ISMB Seminar Series Redox regulation in health and disease Coordinated and hosted by Prof. Ivan Gout and Dr. Amandine Marechal, except where noted. Talks take place on Wednesdays from 1-2pm on Microsoft Teams via the link in promotional emails.

Towards Understanding Cellular Redox Regulation 30th September Prof. Helmut Sies, Institute for and , Heinrich Heine University Düsseldorf, Düsseldorf, Germany

Redox regulation in ageing 7th October Dr. Helena Cochemé, Redox Biology Group, Imperial College, London, UK

A new twist on type IV pili - cryoEM reveals two distinct filaments assembled by the same bacterium 14th October Dr. Vicki Gold, University of Exeter, Exeter, UK Special host: Prof. Helen Saibil

Glutathione: an antioxidant or a signalling molecule? 21st October Prof. Pietro Ghezzi, Brighton and Sussex Medical School, Brighton, UK

Cryo-EM: From Blobology to Drug Design 28th October Dr. Basil Greber, Institute of Cancer Research, London, UK Special host: Dr. Jerome Gouge

Redox regulation of selective autophagy 4th November Dr. Viktor Korolchuk, , Newcastle upon Tyne, UK

Targeting redox-regulated metabolons in Alzheimer's disease 11th November Prof. Myra Conway, University of the West of England, Bristol, UK

The role of redox-regulated PKG in pulmonary hypertension 18th November Dr. Olena Rudyk, School of Cardiovascular Medicine & Sciences, Kings College, London, UK

Persulfidation in control of cell function 25th November Prof. Elias Arnér, Karolinska Institutet, Sweden

Redox signaling in vascular endothelial cells under defined ambient oxygen levels 2nd December Prof. Giovanni Mann, Free Radical Biology & Medicine, Kings College, London, UK

The Type VII protein system of Staphylococcus aureus 9th December Prof. Tracy Palmer, Newcastle University, Newcastle upon Tyne, UK

Special host: Prof. Helen Saibil

www.ismb.lon.ac.uk/seminar.html