ORGANIZING COMMITTEE AIM Catarina Brito This is an introductory course to Drug development, Animal Cell Technology Unit, IBET/ITQB-UNL providing an overview of the field, offering basic aspects Apartado 12 and pharmaceutical application. It will be of interest to 2780-901 Oeiras those starting research or development activity in Drug Portugal Development, both form Academia and Companies (Lab DRUG DEVELOPMENT Tel.: +351 21 4469434 managers, Scientists, Post-Docs, PhD students and E-mail: [email protected] Engineers). It is also of interest for those wishing an up- COURSE 2018 date of the state-of-the-art of Drug Development in a THIRD EDITION Heinz Ruffner short course. Novartis CH-4056 Basel st rd WSJ-Fabrikstrasse 22-4.025.1 COURSE OUTLINE September 30 to October 3 , 2018 Switzerland Tel +41 79 863 5219 The course is planned in an intensive three-day schedule Llafranc, / Email: [email protected] with a number of participants limited to 30 in order to facilitate the interaction among them and with the lecturers. Lecturers will stay for the entire course duration. Hansjörg Hauser Helmholtz Centre for Infection Research (HZI) The course will touch the following aspects in blocks: Inhoffenstrasse 7 38124 Braunschweig 1 Cellular assays for target identification/validation Germany 2 Engineering cells for drug screening and validation Tel.: +49 531 6181 5000 3 Cell selection: primary cells, stem cells, organoids Email: [email protected] 4 Biochemical assays 5 Biomarkers 6 Animal models including PK/PD FEE 7 Assays bridging in vitro and in vivo 8 Toxicology 900 Euros for academic participants and 1,500 Euros for 9 Production of reproducible cell material & criteria industry participants. 10 Assay automation The fee covers course registration and materials (ebook), 11 Data analysis and storage accommodation in two-bed rooms (shared with another participant), meals, transportation from/to airport The program has slots dedicated to the preparation and (see the time schedule for the bus below) as well as the presentation of case studies by participants, and provides Photos: www.ibet.pt social event. Participants have the possibility to be hosted time for discussion with the lecturers. in single room (limited to availability) at an extra cost of With the contribution of: 125 Euros to be paid directly in the hotel. A limited number of grants, covering the Course fee (not travel cost), are provided by ESACT. Applicants to the grants LECTURERS should indicate it in the Course application, together with a Confirmed lecturers include: Catarina Brito (IBET, Portugal),

motivation statement. Priority will be given to young PhD Carsten Pieck (Merck, Germany), Hansjörg Hauser (HZI, students from Academia. All applications should be sent Germany), Reyk Horland (TissUse, Germany), Andre before June 29th. Accepted applicants will be notified by Kleensang (Johns Hopkins University, USA), Eberhard Krauß

July 13th and should register and complete payment by (VIB Headquarters, Belgium), Heinz Ruffner (Novartis, th Switzerland) A C T I P August 15 , 2018. Other information can be found in www.esact.org. PROGRAMME Sunday Monday Tuesday Wednesday Time 30st Sep 1st Oct 2nd Oct 3rd Oct 09:00 Cellular assays for target - Animal models including PK/PD identification/validation 11:00 Group presentations

Arrival to Assays bridging in vitro and in vivo Engineering cells for drug 11:30- 13:30 Barcelona airport or & screening and validation airport - Toxicology

13:30-15:30 transfer to Lunch and free time Hotel Terramar Drug Development Course 2015 nd in Llafranc Cell selection: primary cells, Production of reproducible cell 2 edition 15:30-16:30 stem cells, organoids material & criteria check-in at hotel Course adjournment, 17:15-18:15 Biochemical assays Assay automation hotel check-out and

Overview and departure to 18:30-19:30 Biomarkers Data analysis and storage introduction Barcelona/Girona airports

20:30 Dinner

LOCATION AND TRAVEL INFORMATION Llafranc, Costa Brava / Spain

The course will be held in Hotel Terramar, a three star hotel (www.hterramar.com) in a small town named Llafranc in the heart of Costa Brava, Girona, Spain. The hotel is right on a very nice sandy beach, providing a cosy and relaxing atmosphere for the participants. Weather in Llafranc at this time of the year is generally pleasant. Travel organization to the meeting site is of participants responsibility, ensuring their participation to the full course. REGISTRATION and CONTACT Access by road from Girona airport (30 min) or Barcelona airport (90 min) is suggested. Registration deadline is August 15th, 2018 st IMPORTANT NOTE: ONE BUS will be leaving from Barcelona airport at 14h on Sunday, 30 September to drive participants to Hotel Terramar at Updated information will be available at ESACT website Llafranc. On Wednesday, 3rd of October, ONE BUS will be leaving from Hotel Terramar at 15h to drive participants to Barcelona airport. (www.esact.org)

Contact for registration: ESACT office - Birgit Marckhgott E-mail: [email protected]