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© Angie D. Branson Photography HOW TO PACKAGE AND READ YOUR DNA University ofColoradoatBoulderand Howard HughesMedicalInstitute Rector oftheUniversity ofVienna President oftheÖAW HEINZ W. ENGL ANTON ZEILINGER WELCOME REMARKS KAROLIN LUGER 6 JUNGLE ADVENTURES IN THE TH HANS TUPPY-LECTURE UNIVERSITÄTSRING 1, 1010VIENNA UNIVERSITY OF VIENNA UNIVERSITY GROSSER FESTSAAL MARCH 24,2020 MARCH 6:30 P.M. Please register: After thelecture,youwillbe invited toareception. ormolecular biology research. to significantly contributed have who Austria excellent researchersto known austrianbiochemist and aimatbringing of University the well-the this AustrianViennaand (ÖAW)of Sciences honor of in Academy of series lecture joint a are Tuppy-Lectures“ „Hans The became amemberoftheEuropeanMolecularBiologyOrganization. since 2017. In 2018, she was elected to the National Academy of Sciences and Howard Prize the in 2007 and is at a member of the investigator American Academy of an Arts and Sciences and Hughes Boulder Medical Institute. Luger received Colorado, the State Science of of Vorarlberg’s State of University structure the three-dimensional at the of Biochemistry of Chair discoveryEndowed Jennie-Smoly-Caruthers the is She chromatin. the for and with work her for known biochemist Austrian-American an is Luger Karolin for theemergenceofallmulti-cellularorganismsonearth. essential was that acquisition essential and early very principles, a been have must packaging which DNA of origin evolutionary the of question intriguing decodes theinformation.Morerecently,theyhave beguntoaddressthe and studythemechanicsofelaboratecomplicatedmachinerythat structure investigatingits are They nucleus. the in organization DNA of details Overmolecular the years,in 25 interested past been the has lab Luger‘s Karolin (DNA repair). damage disease-causing and damaging repair to efforts vital and endless cell’s faithful duplication the of the entire ), genome during cell (gene division (DNA replication), DNA and the the in stored information the to access wrapped tightly affects profoundly this is and nucleosomes, called DNA complexes nucleoprotein All into molecule. thin impossibly and long an DNA, incredibly on encoded is body human the in cell each for blueprint entire The without yourhelp. in every single one of the trillions of cells inyourbody, all the time, and entirely couldyou worth Andhow of text that is written on each hair? books phone This~ 40 ‘mission impossible’ of is equivalent performed the in ortangles? names different seventeen find possibly knots creating without and confinement, How wouldyou then split each hair into two, without removing it from its How doyou pack 46 human hairs, each 350 meters inlength, into a golf ball? www.oeaw.ac.at/anmeldung/tuppy-lecture