Published online: 2020-01-22 Original Papers Antiviral Activity of a Arisaema Tortuosum Leaf Extract and Some of its Constituents against Herpes Simplex Virus Type 2 Authors Massimo Rittà1*, Arianna Marengo 2*, Andrea Civra 1, David Lembo 1, Cecilia Cagliero 2, Kamal Kant 3,UmaRanjanLal3, Patrizia Rubiolo 2, Manik Ghosh 3, Manuela Donalisio 1 Affiliations Correspondence 1 Department of Clinical and Biological Sciences, Dr. Manik Ghosh University of Torino, Orbassano, Torino, Italy Department of Pharmaceutical Sciences & Technology, 2 Department of Drug Science and Technology, Birla Institute of Technology University of Torino, Torino, Italy Mesra, Ranchi, Jharkhand 835215, India 3 Department of Pharmaceutical Sciences & Technology, Phone: + 916512276247, Fax: + 916512275401 Birla Institute of Technology, Mesra, Ranchi, India
[email protected] Key words Supporting information available online at Arisaema tortuosum ‑ , Araceae, HSV 2, antiviral activity, http://www.thieme-connect.de/products apigenin, luteolin ABSTRACT received July 18, 2019 revised December 19, 2019 Infections caused by HSV-2 are a public health concern world- accepted December 31, 2019 wide, and there is still a great demand for the discovery of novel anti-herpes virus agents effective against strains resis- Bibliography tant to current antiviral agents. In this context, medicinal DOI https://doi.org/10.1055/a-1087-8303 plants represent an alternative source of active compounds published online January 22, 2020 | Planta Med 2020; 86: for developing efficient antiviral therapies. The aim of this – 267 275 © Georg Thieme Verlag KG Stuttgart · New York | study was to evaluate the antiviral activity of Arisaema tortuo- ‑ ISSN 0032 0943 sum, a plant used in the traditional medicine of India.