Global Bond Fund D: JGBDX As of 6/30/21

Global Bond Fund D: JGBDX as of 6/30/21

Portfolio Construction Insight Sector Allocation (%) Fund Bloomberg Barclays Global Aggregate Bond Index Traditional Fixed Income Global Multi-Sector Exposure Treasuries 43.67 52.99 Credit-Investment Grade 23.46 18.59 Government Related 10.35 14.51 Why Invest Credit-High Yield 8.28 — MBS 5.75 10.44 „ Dynamic, global multi-sector portfolio designed to serve as a core holding Inflation Linked 4.52 — ABS 1.11 0.14 „ Seeks superior risk-adjusted returns relative to the benchmark over a market cycle CMO 0.37 — Cash & Equivalents 2.49 — „ Utilizes rigorous risk management and portfolio construction framework Calendar Year Returns (%) Portfolio Management Class D Shares Bloomberg Barclays Global Aggregate Bond Index Andrew Mulliner, CFA Nick Maroutsos Manager since 2019 Manager since 2020 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 Helen Anthony, CFA Manager since 2020

Fund Overview 6.65 8.02 -2.01 5.58 -4.36 0.25 7.26 -2.37 5.90 13.12 5.64 4.32 -2.60 0.59 -3.15 2.09 7.39 -1.20 6.84 9.20 Objective: Total return, consistent with preservation of capital Morningstar Category: World Bond Assets: $245.06M Inception Date: 12/28/10

Since Inception Expense Ratios (%) Gross Net Performance (%) 2Q21 YTD 1 yr 3 yr 5 yr 10 yr (12/28/10) Class D 0.93 0.73 Class D Shares 1.63 -2.98 3.94 4.84 2.85 2.85 3.19 As of the most recent prospectus. Bloomberg Barclays Global 1.31 -3.21 2.63 4.23 2.34 2.05 2.52 Net expense ratios reflect the expense waiver, if any, Aggregate Bond Index contractually agreed to through at least 10/27/21. Returns quoted are past performance and do not guarantee future results; current performance may be lower or higher. Investment returns and principal value will vary; there may be a gain or loss when shares are sold. For the most recent month-end performance call 800.525.3713 or visit janushenderson.com/allfunds.

Continued on back page. Global Bond Fund (as of 6/30/21)

Fund Characteristics Risk Statistics (3 Year) Fund Index Number of Holdings: Debt Issues 217 Alpha 0.66 — Weighted Average Maturity (years) 9.16 Beta 1.00 1.00 Effective Duration (years) 8.02 R-squared (%) 88.22 100.00 Distribution Frequency Monthly Standard Deviation 4.71 4.44 30-Day SEC Yield Class D Shares (%) 1.03/0.82 (with/without waivers) Sharpe Ratio 0.76 0.66 Statistics are for Class I Shares. Top Countries (%) Fund Index United States 31.74 36.66 Credit Quality of Japan 12.73 13.68 Fixed Income Holdings (%) Fund Index United Kingdom 8.97 5.35 Aaa 22.46 36.97 China 8.52 7.64 Aa 14.96 15.28 Canada 4.74 3.54 A 30.26 31.62 Spain 4.12 2.43 Baa 20.61 16.13 Supranational 2.94 2.17 Ba 6.23 — Belgium 2.55 1.03 B 2.66 — Indonesia 2.42 0.56 Not Rated 0.33 — Italy 2.29 3.51 Credit quality ratings reflect the middle rating received from Moody’s, Standard & Poor’s and Fitch, where all three agencies have provided a rating. If only two agencies rate a security, the lowest rating is used. If only one agency rates a security, that rating is used. Ratings are measured on a scale that ranges from Aaa (highest) to D (lowest). Top Currencies (%) Fund Index United States Dollar 39.99 41.98 Maturity Breakdown of European Euro 21.79 23.44 Fixed Income Holdings (%) Fund Index Japanese Yen 13.33 13.28 < 1 yr 1.64 0.93 Pound Sterling 7.12 5.01 1 - 3 yrs 9.74 20.74 Chinese Renminbi 7.00 6.95 3 - 5 yrs 23.90 17.49 Developed vs. Emerging 5 - 7 yrs 5.28 12.03 7 - 10 yrs 39.40 13.90 Market Exposure (%) Fund Index 10 - 20 yrs 7.60 13.83 Non-U.S. Developed 42.21 47.95 > 20 yrs 9.62 21.08 U.S. 31.73 36.66 N/A 0.33 — Non-U.S. Emerging 20.63 13.22 Other 2.94 2.17

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Index represents the Bloomberg Barclays Global Aggregate Bond Index. Bloomberg Barclays Global Aggregate Bond Index is a broad-based measure of the Returns include reinvestment of dividends and capital gains. Returns greater than one global investment grade fixed-rate debt markets. Alpha compares risk-adjusted year are annualized. performance relative to an index. Positive alpha means outperformance on a risk- adjusted basis. Beta measures the volatility of a security or portfolio relative to an index. There is no assurance the stated objective(s) will be met. Less than one means lower volatility than the index; more than one means greater Equity country, regional, sector and industry weights primarily based on MSCI and GICS volatility. R-squared (R2) measures the relationship between portfolio and index classifications. Fixed income country, regional, sector and industry weights primarily performance on a scale of 0.00 (0%) to 1.00 (100%). A higher R2 indicates more of the based on Bloomberg classifications. portfolio's performance is affected by market movements and vice versa. Standard Investing involves risk, including the possible loss of principal and fluctuation Deviation measures historical volatility. Higher standard deviation implies greater of value. volatility. Sharpe Ratio measures risk-adjusted performance using excess returns versus Derivatives can be highly volatile and more sensitive to changes in economic or the "risk-free" rate and the volatility of those returns. A higher ratio means better return market conditions than other investments. This could result in losses that exceed per unit of risk. Duration measures a bond price’s sensitivity to changes in interest rates. the original investment and may be magnified by leverage. The longer a bond’s duration, the higher its sensitivity to changes in interest rates and vice versa. Foreign securities are subject to additional risks including currency fluctuations, political and economic uncertainty, increased volatility, lower liquidity and Please consider the charges, risks, expenses and investment objectives differing financial and information reporting standards, all of which are carefully before investing. For a prospectus or, if available, a summary magnified in emerging markets. prospectus containing this and other information, please call Janus Fixed income securities are subject to interest rate, inflation, credit and default Henderson at 800.525.3713 or download the file from risk. The bond market is volatile. As interest rates rise, bond prices usually fall, janushenderson.com/reports. Read it carefully before you invest or and vice versa. The return of principal is not guaranteed, and prices may decline send money. if an issuer fails to make timely payments or its credit strength weakens. Janus Henderson is a trademark of Janus Henderson Group plc or one of its subsidiaries. Increased portfolio turnover may result in higher expenses and potentially higher © Janus Henderson Group plc. net taxable gains or losses. Janus Henderson Distributors Index performance does not reflect the expenses of managing a portfolio as an index is unmanaged and not available for direct investment. C-0621-38658 10-15-21 299-15-27779 07-21