University of North Dakota UND Scholarly Commons Biomedical Sciences Faculty Publications Department of Biomedical Sciences 2-2020 Role of endolysosomes and inter-organellar signaling in brain disease Zahra Afghah Xuesong Chen University of North Dakota,
[email protected] Jonathan David Geiger University of North Dakota,
[email protected] Follow this and additional works at: https://commons.und.edu/bms-fac Part of the Medicine and Health Sciences Commons Recommended Citation Afghah, Zahra; Chen, Xuesong; and Geiger, Jonathan David, "Role of endolysosomes and inter-organellar signaling in brain disease" (2020). Biomedical Sciences Faculty Publications. 1. https://commons.und.edu/bms-fac/1 This Article is brought to you for free and open access by the Department of Biomedical Sciences at UND Scholarly Commons. It has been accepted for inclusion in Biomedical Sciences Faculty Publications by an authorized administrator of UND Scholarly Commons. For more information, please contact
[email protected]. Neurobiology of Disease 134 (2020) 104670 Contents lists available at ScienceDirect Neurobiology of Disease journal homepage: www.elsevier.com/locate/ynbdi Review Role of endolysosomes and inter-organellar signaling in brain disease T ⁎ Zahra Afghah, Xuesong Chen, Jonathan D. Geiger Department of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota 58201, United States of America ARTICLE INFO ABSTRACT Keywords: Endosomes and lysosomes (endolysosomes) are membrane bounded organelles that play a key role in cell sur- Endolysosomes vival and cell death. These acidic intracellular organelles are the principal sites for intracellular hydrolytic Mitochondria activity required for the maintenance of cellular homeostasis.