2. Drug Statistics and Trends
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Hallucinogens - LSD, Peyote, Psilocybin, and PCP
Hallucinogens - LSD, Peyote, Psilocybin, and PCP Hallucinogenic compounds found in some • Psilocybin (4-phosphoryloxy-N,N- plants and mushrooms (or their extracts) dimethyltryptamine) is obtained from have been used—mostly during religious certain types of mushrooms that are rituals—for centuries. Almost all indigenous to tropical and subtropical hallucinogens contain nitrogen and are regions of South America, Mexico, and classified as alkaloids. Many hallucinogens the United States. These mushrooms have chemical structures similar to those of typically contain less than 0.5 percent natural neurotransmitters (e.g., psilocybin plus trace amounts of acetylcholine-, serotonin-, or catecholamine- psilocin, another hallucinogenic like). While the exact mechanisms by which substance. hallucinogens exert their effects remain • PCP (phencyclidine) was developed in unclear, research suggests that these drugs the 1950s as an intravenous anesthetic. work, at least partially, by temporarily Its use has since been discontinued due interfering with neurotransmitter action or to serious adverse effects. by binding to their receptor sites. This DrugFacts will discuss four common types of How Are Hallucinogens Abused? hallucinogens: The very same characteristics that led to • LSD (d-lysergic acid diethylamide) is the incorporation of hallucinogens into one of the most potent mood-changing ritualistic or spiritual traditions have also chemicals. It was discovered in 1938 led to their propagation as drugs of abuse. and is manufactured from lysergic acid, Importantly, and unlike most other drugs, which is found in ergot, a fungus that the effects of hallucinogens are highly grows on rye and other grains. variable and unreliable, producing different • Peyote is a small, spineless cactus in effects in different people at different times. -
Hallucinogens - LSD, Peyote, Psilocybin, and PCP
Information for Behavioral Health Providers in Primary Care Hallucinogens - LSD, Peyote, Psilocybin, and PCP What are Hallucinogens? Hallucinogenic compounds found in some plants and mushrooms (or their extracts) have been used— mostly during religious rituals—for centuries. Almost all hallucinogens contain nitrogen and are classified as alkaloids. Many hallucinogens have chemical structures similar to those of natural neurotransmitters (e.g., acetylcholine-, serotonin-, or catecholamine-like). While the exact mechanisms by which hallucinogens exert their effects remain unclear, research suggests that these drugs work, at least partially, by temporarily interfering with neurotransmitter action or by binding to their receptor sites. This InfoFacts will discuss four common types of hallucinogens: LSD (d-lysergic acid diethylamide) is one of the most potent mood-changing chemicals. It was discovered in 1938 and is manufactured from lysergic acid, which is found in ergot, a fungus that grows on rye and other grains. Peyote is a small, spineless cactus in which the principal active ingredient is mescaline. This plant has been used by natives in northern Mexico and the southwestern United States as a part of religious ceremonies. Mescaline can also be produced through chemical synthesis. Psilocybin (4-phosphoryloxy-N, N-dimethyltryptamine) is obtained from certain types of mushrooms that are indigenous to tropical and subtropical regions of South America, Mexico, and the United States. These mushrooms typically contain less than 0.5 percent psilocybin plus trace amounts of psilocin, another hallucinogenic substance. PCP (phencyclidine) was developed in the 1950s as an intravenous anesthetic. Its use has since been discontinued due to serious adverse effects. How Are Hallucinogens Abused? The very same characteristics that led to the incorporation of hallucinogens into ritualistic or spiritual traditions have also led to their propagation as drugs of abuse. -
Slang Terms and Code Words: a Reference for Law Enforcement
UNCLASSIFIED Slang Terms and Code Words: A Reference for Law DEA Enforcement Personnel Intelligence DEA-HOU-DIR-022-18 July 2018 ReportBrief 1 UNCLASSIFIED UNCLASSIFIED DEA Intelligence Report Executive Summary This Drug Enforcement Administration (DEA) Intelligence Report contains new and updated information on slang terms and code words from a variety of law enforcement and open sources, and serves as an updated version to the product entitled “Drug Slang Code Words” published by the DEA in May 2017. It is designed as a ready reference for law enforcement personnel who are confronted with hundreds of slang terms and code words used to identify a wide variety of controlled substances, designer drugs, synthetic compounds, measurements, locations, weapons, and other miscellaneous terms relevant to the drug trade. Although every effort was made to ensure the accuracy and completeness of the information presented, due to the dynamics of the ever-changing drug scene, subsequent additions, deletions, and corrections are inevitable. Future addendums and updates to this report will attempt to capture changed terminology to the furthest extent possible. This compendium of slang terms and code words is alphabetically ordered, with new additions presented in italic text, and identifies drugs and drug categories in English and foreign language derivations. Drug Slang Terms and Code Wordsa Acetaminophen and Oxycodone Combination (Percocet®) 512s; Bananas; Blue; Blue Dynamite; Blueberries; Buttons; Ercs; Greenies; Hillbilly Heroin; Kickers; M-30s; -
Drug and Alcohol Abuse Prevention Handbook FOREWARD
Drug and Alcohol Abuse Prevention Handbook FOREWARD Grayson College recognizes that the illicit use of drugs and/or the abuse of alcohol are a persistent health problem of major proportion affecting our society physically, mentally, and socially. Illicit drug use and /or alcohol abuse can adversely affect an individual’s personal life, safety, health, and mental and physical performance. It is the intent of GC to provide employees and students pertinent information related to illicit drug use and/or alcohol abuse in an effort to prevent such harm. GC is committed to promoting and maintaining a work and academic environment that is free from illegal alcohol and drug use and abuse, in accordance with all federal, state, and local laws. Students, employees, and visitors are prohibited from possessing, consuming, manufacturing, dispensing, or being under the influence of alcohol/illegal drugs or engaging in improper self- medication while on college property or college business. Any member of the college community who violates this policy is subject to both prosecution and punishment under federal, state, and local laws to disciplinary proceedings by the college. This alcohol/drug policy is not designed to punish people for seeking rehabilitation. All information about those individuals who voluntarily avail themselves of drug or alcohol counseling or rehabilitation will not be used as a basis for disciplinary action or be used against an individual in any way. College employees and students who violate the alcohol/drug policy shall be informed about and referred to services to assist them in determining whether they are abusing drugs and alcohol or are chemically dependent. -
Molecular Modeling of Major Tobacco Alkaloids in Mainstream Cigarette Smoke Caren Kurgat, Joshua Kibet* and Peter Cheplogoi
Kurgat et al. Chemistry Central Journal (2016) 10:43 DOI 10.1186/s13065-016-0189-5 RESEARCH ARTICLE Open Access Molecular modeling of major tobacco alkaloids in mainstream cigarette smoke Caren Kurgat, Joshua Kibet* and Peter Cheplogoi Abstract Background: Consensus of opinion in literature regarding tobacco research has shown that cigarette smoke can cause irreparable damage to the genetic material, cell injury, and general respiratory landscape. The alkaloid family of tobacco has been implicated is a series of ailments including addiction, mental illnesses, psychological disorders, and cancer. Accordingly, this contribution describes the mechanistic degradation of major tobacco alkaloids including the widely studied nicotine and two other alkaloids which have received little attention in literature. The principal focus is to understand their energetics, their environmental fate, and the formation of intermediates considered harmful to tobacco consumers. Method: The intermediate components believed to originate from tobacco alkaloids in mainstream cigarette smoke were determined using as gas-chromatography hyphenated to a mass spectrometer fitted with a mass selective detector (MSD) while the energetics of intermediates were conducted using the density functional theory framework (DFT/B3LYP) using the 6-31G basis set. Results: The density functional theory calculations conducted using B3LYP correlation function established that the scission of the phenyl C–C bond in nicotine and β-nicotyrine, and C–N phenyl bond in 3,5-dimethyl-1-phenylpyrazole were respectively 87.40, 118.24 and 121.38 kcal/mol. The major by-products from the thermal degradation of nicotine, β-nicotyrine and 3,5-dimethyl-1-phenylpyrazole during cigarette smoking are predicted theoretically to be pyridine, 3-methylpyridine, toluene, and benzene. -
Smokable Cocaine Markets in Latin America and the Caribbean a Call for a Sustainable Policy Response
Smokable cocaine markets in Latin America and the Caribbean A call for a sustainable policy response ideas into movement AUTHORS: Ernesto Cortés and Pien Metaal EDITOR: Anthony Henman DESIGN: Guido Jelsma - www.guidojelsma.nl COVER PHOTO: Man smoking crack pipe Colombia, L. Niño. ACKNOWLEDGEMENTS: This publication was made possible through the financial support of the Open Society Foundation (OSF) and the Global Partnership on Drug Policies and Development (GPDPD). GPDPD is a project implemented by the Deutsche Gesellschaft für Internationale Zusammenarbeit (GIZ) GmbH on behalf of the Federal Ministry for Economic Cooperation and Development (BMZ) and under the political patronage of the Federal Government’s Drug Commissioner. The contents of this report are the sole responsibility of TNI and can under no circumstances be regarded as reflecting the position of the donors. PUBLICATION DETAILS: Contents of the report may be quoted or reproduced for non-commercial purposes, provided that the source of information is properly cited. TRANSNATIONAL INSTITUTE (TNI) De Wittenstraat 25, 1052 AK Amsterdam, The Netherlands Tel: +31-20-6626608, Fax: +31-20-6757176 E-mail: [email protected] www.tni.org/drugs @DrugLawReform Drugsanddemocracy Amsterdam, December 2019 2 | Smokable cocaine markets in Latin America and the Caribbean transnationalinstitute Contents Introduction 4 Methodological approach 6 The Substance(s) 8 Smokable cocaine in Cochabamba (Bolivia) in the early 1990s 9 Users 14 Impact on health 17 The Market 21 Harm Reduction experiences 25 Conclusions and Discussion 28 Policy Recommendations 29 Good Practices: examples from Brazil 30 Bibiography and references 32 International smokable cocaines working group 33 Endnotes 34 transnationalinstitute Smokable cocaine markets in Latin America and the Caribbean | 3 Introduction regions. -
Interactions Between Ethanol and Cocaine, Amphetamine, Or MDMA in the Rat: Thermoregulatory and Locomotor Effects
Psychopharmacology DOI 10.1007/s00213-007-1007-5 ORIGINAL INVESTIGATION Interactions between ethanol and cocaine, amphetamine, or MDMA in the rat: thermoregulatory and locomotor effects Sami Ben Hamida & Erin Plute & Brigitte Cosquer & Christian Kelche & Byron C. Jones & Jean-Christophe Cassel Received: 22 May 2007 /Accepted: 29 October 2007 # Springer-Verlag 2007 Abstract duced by EtOH alone. Conversely, EtOH attenuated Rationale (±)-3,4-methylenedioxymethamphetamine MDMA-related hyperthermia, an effect increasing across (MDMA, ecstasy) is often taken recreationally with ethanol treatment days. These results demonstrate that the interac- (EtOH). In rats, EtOH may potentiate MDMA-induced tion between MDMA and EtOH may be different from the hyperactivity, but attenuate hyperthermia. interaction between EtOH and AMPH or COCA. Objective Experiment 1 compared the interactions between Conclusion Because of potential health-related consequen- EtOH (1.5 g/kg) and MDMA (6.6 mg/kg) with EtOH + ces of such polydrug misuse, it is worth identifying the cocaine (COCA; 10 mg/kg) and EtOH + amphetamine mechanisms underlying these interactions, especially be- (AMPH; 1 mg/kg) on locomotor activity and thermoregu- tween EtOH and MDMA. Given the different affinity lation. Experiment 2 used a weaker dose of MDMA profiles of the three drugs for serotonin, dopamine, and (3.3 mg/kg) and larger doses of COCA (20 mg/kg) and norepinephrine transporters, our results appear compatible AMPH (2 mg/kg). with the possibility of an important role of serotonin in at Materials and methods Drug treatments were administered least the EtOH-induced potentiation of MDMA-induced on four occasions (2, 5, and 2 days apart, respectively; hyperlocomotion. -
Songs by Title
Songs by Title Title Artist Title Artist #1 Goldfrapp (Medley) Can't Help Falling Elvis Presley John Legend In Love Nelly (Medley) It's Now Or Never Elvis Presley Pharrell Ft Kanye West (Medley) One Night Elvis Presley Skye Sweetnam (Medley) Rock & Roll Mike Denver Skye Sweetnam Christmas Tinchy Stryder Ft N Dubz (Medley) Such A Night Elvis Presley #1 Crush Garbage (Medley) Surrender Elvis Presley #1 Enemy Chipmunks Ft Daisy Dares (Medley) Suspicion Elvis Presley You (Medley) Teddy Bear Elvis Presley Daisy Dares You & (Olivia) Lost And Turned Whispers Chipmunk Out #1 Spot (TH) Ludacris (You Gotta) Fight For Your Richard Cheese #9 Dream John Lennon Right (To Party) & All That Jazz Catherine Zeta Jones +1 (Workout Mix) Martin Solveig & Sam White & Get Away Esquires 007 (Shanty Town) Desmond Dekker & I Ciara 03 Bonnie & Clyde Jay Z Ft Beyonce & I Am Telling You Im Not Jennifer Hudson Going 1 3 Dog Night & I Love Her Beatles Backstreet Boys & I Love You So Elvis Presley Chorus Line Hirley Bassey Creed Perry Como Faith Hill & If I Had Teddy Pendergrass HearSay & It Stoned Me Van Morrison Mary J Blige Ft U2 & Our Feelings Babyface Metallica & She Said Lucas Prata Tammy Wynette Ft George Jones & She Was Talking Heads Tyrese & So It Goes Billy Joel U2 & Still Reba McEntire U2 Ft Mary J Blige & The Angels Sing Barry Manilow 1 & 1 Robert Miles & The Beat Goes On Whispers 1 000 Times A Day Patty Loveless & The Cradle Will Rock Van Halen 1 2 I Love You Clay Walker & The Crowd Goes Wild Mark Wills 1 2 Step Ciara Ft Missy Elliott & The Grass Wont Pay -
Report of the International Narcotics Control Board for 2015 (E/INCB/2015/1) Is Supple- Mented by the Following Reports
INTERNATIONAL NARCOTICS CONTROL BOARD REPORT REPORT 2015 INTERNATIONAL NARCOTICS CONTROL BOARD CONTROL NARCOTICS INTERNATIONAL Report 2015 EMBARGO Observe release date: Not to be published or broadcast before Wednesday, 2 March 2016, at 1100 hours (CET) UNITED NATIONS CAUTION Reports published by the International Narcotics Control Board in 2015 TheReport of the International Narcotics Control Board for 2015 (E/INCB/2015/1) is supple- mented by the following reports: Report of the International Narcotics Control Board on the Availability of Internationally Controlled Drugs: Ensuring Adequate Access for Medical and Scientific Purposes (E/INCB/2015/1/Supp.1) Narcotic Drugs: Estimated World Requirements for 2016—Statistics for 2014 (E/INCB/2015/2) Psychotropic Substances: Statistics for 2014—Assessments of Annual Medical and Scientific Requirements for Substances in Schedules II, III and IV of the Convention on Psychotropic Substances of 1971 (E/INCB/2015/3) Precursors and Chemicals Frequently Used in the Illicit Manufacture of Narcotic Drugs and Psychotropic Substances: Report of the International Narcotics Control Board for 2015 on the Implementation of Article 12 of the United Nations Convention against Illicit Traffic in Narcotic Drugs and Psychotropic Substances of 1988 (E/INCB/2015/4) The updated lists of substances under international control, comprising narcotic drugs, psychotropic substances and substances frequently used in the illicit manufacture of narcotic drugs and psychotropic substances, are contained in the latest editions of the annexes to the statistical forms (“Yellow List”, “Green List” and “Red List”), which are also issued by the Board. Contacting the International Narcotics Control Board The secretariat of the Board may be reached at the following address: Vienna International Centre Room E-1339 P.O. -
A User's Guide to Methamphetamine
A USER’S GUIDE TO METHAMPHETAMINE A self-help guide to reduce harm for people who use methamphetamine 1st Edition, March 2017 Acknowledgements This booklet was adapted from an original publication created by The National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia. This information does not constitute medical advice. Please seek the immediate help of a qualified medical practitioner about any personal health concerns. This booklet is being distributed for information purposes only. In the current state of crisis related to crystal methamphetamine, this booklet is intended as a guide to reduce harm for people who use methamphetamine. It lists the most common features of methamphetamine use, ways to reduce harm associated with the use of meth, and strategies for cutting down and quitting. The best way to avoid problems with drugs is to not use them. We are grateful for the contributions of the Integrated Drug Strategies in Waterloo Region and Guelph Wellington, in particular the leadership of Adrienne Crowder and Lindsay Sprague. Don Roth, Kerry Manthenga, Shirley Hilton, and our community review team provided great support and helpful edits. Marcey Gray provided exemplary skill on the design, images and editing, with final expert assistance from Arkay Design and Print. We are thankful for the financial support to print copies from the Waterloo-Wellington Human Services and Justice Coordinating Committee. For more information please contact: Wellington Guelph Drug Strategy www.wgdrugstrategy.ca Waterloo Region Integrated Drugs Strategy www.waterlooregiondrugstrategy.ca Circulated with the support of: WaterlooRegion Integrated Drugs Strategy WaterlooRegion Integrated Drugs Strategy The best way to avoid problems with drugs is to not use them. -
What Is Cocaine?
WHAT IS COCAINE? AN EDUCATIONAL FACT SHEET FROM THE FLORIDA ALCOHOL & DRUG ABUSE ASSOCIATION Cocaine is a powerful central nervous sys- OTHER WAYS OF USING COCAINE tem stimulant that comes from the South Ameri- The most dangerous form of smokable cocaine can coca bush. The cocaine (cocaine hydrochlo- is coca paste made by using gasoline or sulfuric acid ride) most commonly used in the U.S. is a white to extract a smokable paste. The paste is dried and crystalline powder extracted from coca leaves. smoked in a pipe or crushed into a cigarette. The cocaine bought on the street is a mixture of pure cocaine and other substances such as talc, Cocaine may be used with other drugs to pro- flour, laxatives, sugar, local anesthetics and other duce a variety of effects. “Speedballing” is the com- stimulants or powders that are added to stretch bination of cocaine and heroin in a syringe for in- the supply and increase the seller’s profit. jection. “Spaceballing” is the sprinkling of liquid Users buy powdered cocaine in grams (1/ PCP (Phencyclidine) on crack cocaine before smok- 28 of an ounce) or in fractions of a gram called ing. “Champagne” is the combination of cocaine and “quarters” or “eighths.” Often, cocaine is snorted marijuana. through the nose. Razor blades are used to crush any large rocks or particles of cocaine and to form “lines” that make snorting easier. Some SHORT-TERM EFFECTS users inject cocaine into a muscle or vein; others When cocaine is snorted, the effects begin convert it into a smokable form called freebase. -
Negrocity: an Interview with Greg Tate
City University of New York (CUNY) CUNY Academic Works Publications and Research New York City College of Technology 2012 Negrocity: An Interview with Greg Tate Camille Goodison CUNY New York City College of Technology How does access to this work benefit ou?y Let us know! More information about this work at: https://academicworks.cuny.edu/ny_pubs/731 Discover additional works at: https://academicworks.cuny.edu This work is made publicly available by the City University of New York (CUNY). Contact: [email protected] NEGROCITY An Interview with Greg Tate* by Camille Goodison As a cultural critic and founder of Burnt Sugar The Arkestra Chamber, Greg Tate has published his writings on art and culture in the New York Times, Village Voice, Rolling Stone, and Jazz Times. All Ya Needs That Negrocity is Burnt Sugar's twelfth album since their debut in 1999. Tate shared his thoughts on jazz, afro-futurism, and James Brown. GOODISON: Tell me about your life before you came to New York. TATE: I was born in Dayton, Ohio, and we moved to DC when I was about twelve, so that would have been about 1971, 1972, and that was about the same time I really got interested in music, collecting music, really interested in collecting jazz and rock, and reading music criticism too. It kinda all happened at the same time. I had a subscription to Rolling Stone. I was really into Miles Davis. He was like my god in the 1970s. Miles, George Clinton, Sun Ra, and locally we had a serious kind of band scene going on.