Int J Ophthalmol, Vol. 12, No. 7, Jul.18, 2019 www.ijo.cn Tel: 8629-82245172 8629-82210956 Email:
[email protected] ·Meta-Analysis· Prevalence of amblyopia in congenital blepharoptosis: a systematic review and Meta-analysis Jia-Ying Zhang1,2, Xiao-Wei Zhu1,2, Xia Ding1,2, Ming Lin1,2, Jin Li1,2 1Department of Ophthalmology, Shanghai Ninth People’s and management of amblyopia should be integral to the Hospital, Shanghai Jiao Tong University School of Medicine, treatment of congenital ptosis. Shanghai 200011, China ● KEYWORDS: amblyopia; congenital ptosis; blepharophimosis; 2Shanghai Key Laboratory of Orbital Diseases and Ocular systematic review Oncology, Shanghai 200011, China DOI:10.18240/ijo.2019.07.21 Correspondence to: Jin Li. Department of Ophthalmology, Shanghai Ninth Peolple’s Hospital, Shanghai Jiao Tong Citation: Zhang JY, Zhu XW, Ding X, Lin M, Li J. Prevalence of University School of Medicine, No.639, Zhizaoju Road, amblyopia in congenital blepharoptosis: a systematic review and Shanghai 200011, China.
[email protected] Meta-analysis. Int J Ophthalmol 2019;12(7):1187-1193 Received: 2018-09-25 Accepted: 2019-03-05 INTRODUCTION Abstract ongenital blepharoptosis is an eyelid disorder that ● AIM: To conduct a systematic review and Meta-analysis of C is characterized by an involuntary drooping of the the published literature to evaluate the pooled prevalence upper eyelid since birth. Etiologically, myogenic factors are rate of amblyopia in patients with congenital ptosis. most common, referring to dysgenesis or weakness of the ● METHODS: We searched the PubMed, Embase, the levator muscle and sometimes the superior rectus muscle. Cochrane Central Register of Controlled Trials, China The etiological subtypes of congenital ptosis include simple National Knowledge Infrastructure, Wanfang Data, and congenital ptosis, blepharophimosis-ptosis-epicanthus inversus Chongqing VIP databases for studies reporting the syndrome (BPES), Marcus Gunn jaw-winking syndrome prevalence of amblyopia in patients with congenital ptosis.