Rhodes Biomedicine Weekend THE I RHODES Rhodes Scholars in Health Sciences and Health Equity TRUST

Dr Salim Yusuf A Rhodes Scholar from India, Dr Yusuf is President of the World Heart Federation. His research has been focused on changing how cardiovascular disease is treated and prevented through large-scale clinical trials. Salim is recognised for determining the risk factors for heart disease and stroke. His large-scale studies involving tens of thousands of patients in dozens of countries have changed the way some of the world's most deadly health conditions are prevented, treated and managed, including heart disease, stroke, diabetes and blood clots. Salim has published more than 800 articles in refereed journals, rising to the second most cited researcher in the world for 2011. At the World Heart Federation, he is initiating an Emerging Leaders programme in 100 countries with the aim of halving the cardio- vascular disease burden globally within a generation. He was inducted into the Canadian Medical Hall of Fame in April 2014

Dr Pardis Sabeti Associate Professor at the Centre for Systems Biology at and in the Department of Immunology and Infectious Disease at Harvard School of Public Health, and a Senior Associate Member of the of Harvard and MIT. Professor Sabeti developed a breakthrough algorithm that allows geneticists to scan for genes that reveal at work. “With a background in Computational genetics and medicine, I work to develop analytical methods and use rapidly emerging genomic resources to study evolutionary adaptation in humans and the microbes that cause human disease. My lab’s main areas of research are studying natural selection in humans, identifying and characterising the underlying functional changes that have shaped our species over time; investigating host and microbe evolution of the devastating disease Lassa virus, Plasmodium falciparum malaria, Ebola virus, and Vibrio cholerae holera.” Dr Pardis Sabeti

Dr Tariro Makadzange Dr Makadzange concentrates her research on HIV/AIDS in Africa and has run an HIV treatment programme in one of the largest hospitals in Harare. “When I received the , I was a young medical student who wanted to do HIV research in Africa and at that time very few labs in the US had directs links or much interest in HIV research in Africa (that has changed significantly). But there was a group at Oxford working in Kenya and developing an HIV vaccine. Receiving the Scholarship profoundly changed my career pathway, widened my vision and opened doors and opportunities. But most importantly allowed me to be inspired by amazing peers from all over the world, many of whom remain very dear friends. There are so few things at that age and stage in life that can have such a profound impact.” Dr Tariro Makadzange Dr Pardis Sabeti Dr Sabeti is Associate Professor at the Centre for Systems Biology at Harvard University and in the Department of Immunology and Infectious Disease at Harvard School of Public Health, and a Senior Associate Member of the Broad Institute of Harvard and MIT. Pardis developed a breakthrough algorithm that allows geneticists to scan for genes that reveal natural selection at work, and is currently working on the Ebola outbreak. “With a background in Computational genetics and medicine, I work to develop analytical methods and use rapidly emerging genomic resources to study evolutionary adaptation in humans and the microbes that cause human disease. My lab’s main areas of research are studying natural selection in humans and investigating host and microbe evolution of the devastating disease Lassa virus, Plasmodium falciparum malaria, Ebola virus, and Vibrio cholerae cholera.” Dr Pardis Sabeti

Rhodes Biomedicine Weekend

Current / recent • Katherine Niehaus Research focuses on using machine learning to combine Scholars genomic and clinical datasets to improve healthcare. • Aku Ntumy DPhil in radiobiology, investigating dNTP metabolism in cancers. • David Springer DPhil in Biomedical Engineering focusing on rheumatic heart disease diagnosis on mobile phones. • Cameron Turtle Founder of Point of Care Technologies, a company that develops molecular medical diagnostic devises that interface with Android- based mobile equipment and is now researching the effect of diseases on cardiac muscle mechanics at the cellular level. • Ben Hunn Researching the role of macroautophagy in Parkinson's disease. • Kristijan Jovanoski Research focus is on the genetics connected to memories and motivation, and in particular the genetic elements inside brain cells which could be responsible for neurodegenerative diseases. • Benjamine Liu Working to leverage advancements in genomics, proteomics, transcriptomics and metabolomics to find better ways to diagnose and treat diseases associated with ageing, including dementia, Alzheimer's, and Parkinson's Disease. • Sheiry Dhillon Research focuses on improving access and quality of obstetric healthcare in low- and middle-income countries. • Aneil Jaswal Working on inequities in the use of healthcare in low- and middle- income countries: patterns and policy responses. Research explores how and why wealth-related inequalities in use of health care vary for different types of treatments. • Ayodele Odutayo Studying the epidemiology & reporting of randomised controlled trials with a comparison of high income and low-middle income countries. • Freya Shearer Previously Co-Director of Upside, an NGO which seeks to impact health development in rural Nepal. Her DPhil project involves mapping the global distribution of Yellow Fever, West Nile Fever and Japanese Encephalitis. • Shmona Simpson Developed novel diagnostics for the detection of Enterovirus 71, the causative agent of Hand, Foot, and Mouth Disease in Southern Vietnam with the Oxford University Clinical Research Unit and currently researching host genetic factors that influence the outcome to HIV-2 infection.

Senior Scholars • Dr Liliane Chamas Working for the World Health Organisation on using mobile Early / mid- technology for noncommunicable diseases. career • Dr Peter Gill Co-founded and developed PedsCases, a medical education website that provides paediatric resources for undergraduate students. • Dr Eileen Cardillo At the University of Pennsylvania’s Centre for Cognitive Neuroscience where she currently works on brain-injured patients in neuropsychological research, with a focus on the neural basis of metaphoric and spatial language, and cognitive and neural changes. Rhodes Biomedicine Weekend

• Dr Samir Sinha Director of Geriatrics at the Mount Sinai and University Health Network, and was appointed to lead the development of a Seniors Strategy in Ontario ‘Living Longer, Living Well’. • Dr Christopher Young Clinical Fellow in Neurosurgery at Groote Schuur and Red Cross Children's Hospital, and advanced stem cell research. • Shaan Gandhi Chief Medical Officer at Wellable Inc, a Boston-based start-up focused on mobile incentives to promote health and wellness. Research focus is on IT solutions to enhance access, improve quality and reduce cost within healthcare. • Dr Kopano Mabaso and Dr Chrystelle Wedi met whilst at Oxford and are now working together on an innovative project to take lifesaving antenatal care to pregnant women in remote/under-served parts of low & middle income countries. • Dr Alisha Wade Clinical Scientist, University of the Witwatersrand, researching chronic disease in developing countries. • Dr Leana Wen Serving as the Baltimore City Health Commissioner, with research focus on patient-centred care. Dr Wen has conducted public health and emergency systems research in Rwanda, D.R. Congo, Nigeria, South Africa, China, Singapore, Slovenia, and Denmark.

Senior Scholars • Dr Jahar Bhattacharya Director of Lung Research at the Division of Pulmonary Later career and Critical Care Medicine at Columbia University Medical Centre. stage • Professor James Collins Professor of Biomedical Engineering, Boston University and Howard Hughes Institute of Medical Research Investigator. MacArthur Fellowship. Made fundamental discoveries concerning the actions of antibiotics. • Dr Atul Gawande Surgical methods innovator, Professor of Surgery at . MacArthur Fellowship. • The Hon Dr Eric Hoskins Ontario's Minister for Health and Long Term Care, medical doctor and former president of War Child Canada. • Dr Robert Munford Chief of Antibacterial Host Defence Section, LCID at the National Institute of Allergy and Infectious Diseases. • Sir John Eccles Won the Nobel Prize for his work as a neurophysiologist studying synapses in the peripheral nervous system. • Dr Griffith Harsh Vice Chair of the Department of Neurosurgery, the Director of the Stanford Brain Tumor Center and as Associate Dean of CME Education at the Stanford University School of Medicine. • Dr Peter Rathjen Internationally recognised expert on stem cell science. Develops stem cell therapies for replacing heart muscle, blood and nerve cells. • Professor Aaron Sloman Philosopher and researcher on artificial intelligence and cognitive science.

Rhodes Biomedicine Weekend

• Professor Elsdon Storey Neurologist - his clinical and research interests are in neurogenetics such as the hereditary ataxias and behavioural neurology, focusing on the dementias. • Dr Timothy Evans Director of the World Bank's Population, Health and Nutrition Division, and innovator in medical training. • Dr Prabhat Jha Founded the Centre for Global Health Research at St Michael’s Hospital in Toronto, where he has directed a variety of large scale population health studies, most notably the Indian Million Death Study on premature mortality. • Dr Trevor Mundel President of the Global Health Division at the Bill & Melinda Gates Foundation. • Dr Christopher Murray Director of the Institute for Health Metrics and Evaluation (IHME), providing data for policy makers around the world to allocate healthcare resources. Led 486 researchers from 302 institutions in 50 countries to produce the Global Burden of Disease reports in 2010 and 2013. Developed the disability adjusted life years (DALY) approach to measuring the global burden of disease.

Dr Dr Lander is one of the principal leaders of the Human Project, and one of 11 inaugural winners of the Breakthrough Prize in Life Sciences. Over the past 15 years, he and his colleagues have created many of the key tools of human genomics and have applied these tools to pioneer new ways to understand the basis of diseases, including cancer, diabetes, and inflammatory diseases. in 2009, President Barack Obama appointed him to co-chair the President’s Council of Advisors on Science and Technology.

“The genome is a fossil record, a landscape, a whole geography of distributions. The thing about the human genome that most surprised me was how many amazing stories there were in it. You might think the genome's just a boring string of letters, like reading the ones and zeros on your hard disk, but the genome is a storybook that's been edited for a couple of billion years.” Dr Eric Lander