JOURNAL OF CLINICAL DIABETOLOGY JCD QUIZ
Select the correct answer
Q1. WFS 1 gene mutation is least commonly associated Q7. MODY 6 is associated with which gene? with which of the following manifestations? a. Juvenile onset diabetes mellitus b. IPF 1 b. Optic atrophy c. HNF 1 beta c. Diabetes insipidus d. Neuro D 1 d. Auditory nerve deafness Q8. All are true about newer insulin pumps, except Q2. Which of the following antibodies has the highest probability of being found in general population touch screen coincidentally? b. Jewel PUMP2 is based on a micro electromechanical systems integrated b. Islet cell antibodies (ICAs) and ultra-precise disposable pump-chip c. Insulin auto antibodies technology d. IA-2 antibody Q3. TECOS trial was done to assess the outcome insulin a. Linagliptin continuous, intravenous infusion of rapid- b. Sitagliptin acting insulin c. Vildagliptin Q9. All are true about saroglitazar, except d. Saxagliptin a. It is well absorbed through the gut Q4. Which of the following molecules has the highest b. It is eliminated via hepatic route impact in reducing glycaemicexcursions? c. Increase sapo lipoprotein CIII level a. Insulin degludec d. It does not produce oedema or weight gain b. Insulin lispro Q10. All are true about intracellular signalling c. Liraglutide mechanisms through which insulin secretion is d. Voglibose regulated, except Q5. Which of the following molecules is an oral GLP1 a. Closure of ATP sensitive potassium channels analogue? are done by glucose and leucine a. Semaglutide b. Increased cytosolic calcium inhibits insulin b. Albiglutide secretion c. Taspoglutide c. Increased cyclic AMP potentiates insulin d. Dulaglutide secretion d. Calcium mobilisation from endoplasmic Q6. All of the following statements regarding reticulum done by acetylcholine glucagon are false, except a. Secreted from delta cells Q11. All are true about the molecular mechanism of b. Hyperglucagonemia is not a component of insulin resistance, except the ominous octet a. A dominant negative mutation in human c. Hyperglucagonemia is seen in both type 1 gamma gene is associated with severe and type 2 diabetes insulin resistance d. Somatostatin analogue is of no help in b. Leptin promotes lipolysis and beta-oxidation glucagonoma of fatty acids, an action similar to insulin
38 | JCD | VOL 3 | NO. 1 | APR-JUNE 2016 c. Reduction in adiponectin is associated with c. Urine ceruloplasmin/creatinine ratio is obesity and insulin resistance higher in diabetics compared to non-diabetic QUIZ d. Resistin functions as a signal to decrease insulin stimulated glucose uptake for diabetic nephropathy Q12. All are false regarding LADA, except Q15. All are true regarding sexual dysfunction in a. Absence of family history of diabetes diabetes, except b. BMI >19 a. In male, there is reduction of urinary c. Opening sugar is not high testosterone level is seen d. Adequate response to OHAs b. Testicular biopsy shows altered Ley dig cell Q13. All are diabetogenic drugs, except distribution c. Psychogenic impotent person will show a. Epalrestat alteration in nocturnal penile tumescence b. Pentamidine during REM sleep c. Thiazides d. The loss of testicular pain sensitivity d. Rosuvastatin suggests neurogenic aetiology Q14. All are true regarding biomarkers of diabetic nephropathy, except albuminuria correlated with the amount of albuminuria
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