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Appendix 2 Coinvestigators Name Location Role Contribution Sebastian Ameriso, Buenos Aires, Site principal Coordinated data MD Argentina investigator collection for site Claudia Nora Buenos Aires, Site principal Coordinated data Gandolfo, MD Argentina investigator collection for site Guillermo Povedano, Buenos Aires, Site principal Coordinated data MD Argentina investigator collection for site Javier Saggesse, MD Buenos Aires, Site investigator Data collection Argentina Claudia Gandolfo, Buenos Aires, Site investigator Data collection MD Argentina Heman Pavon, MD Buenos Aires, Site investigator Data collection Argentina Jorge Cancino, MD Buenos Aires, Site investigator Data collection Argentina Walter Toledo, MD Buenos Aires, Site principal Coordinated data Argentina investigator collection for site Yinin Huang, MD Beijing, China Site principal Coordinated data investigator collection for site Xiping Gong, MD Beijing, China Site investigator Data collection Yetao MA, MD Beijing, China Site investigator Data collection Donghu MI, MD Beijing, China Site investigator Data collection Xiping Gong, MD Beijing, China Site investigator Data collection Yilong Wang, MD Beijing, China Site investigator Data collection Yongjun Wang, MD Beijing, China Site principal Coordinated data investigator collection for site Fran Chandgfend, Beijing, China Site investigator Data collection MD Guo Congtao, MD Beijing, China Site investigator Data collection Jiao Hongyun, MD Beijing, China Site investigator Data collection He Intao, MD Beijing, China Site investigator Data collection Wu Jixing, MD Beijing, China Site investigator Data collection Liu Linlin, MD Beijing, China Site investigator Data collection Song Liquing, MD Beijing, China Site investigator Data collection Tai Liwen, MD Beijing, China Site investigator Data collection Liu Ran, MD Beijing, China Site investigator Data collection Tian Shujuan, MD Beijing, China Site investigator Data collection Liu Wenhong, MD Beijing, China Site investigator Data collection Tak Hong Tsoi, MD Hong Kong, China Site principal Coordinated data investigator collection for site Roxanna Liu, MD Hong Kong, China Site investigator Data collection Roman Flasar, MD Brno, Czech Republic Site principal Coordinated data investigator collection for site Bedřiška Zítková, MD Brno, Czech Republic Site investigator Data collection Michal Reif, MD Brno, Czech Republic Site principal Coordinated data investigator collection for site David Goldemund, Brno, Czech Republic Site investigator Data collection MD Jiří Neumann, MD Chomutov, Czech Site principal Coordinated data Republic investigator collection for site Dagmar Sváčková, Chomutov, Czech Site investigator Data collection MD Republic Daniel Šaňák, MD Oslomouc, , Czech Site principal Coordinated data Republic investigator collection for site Michal Král, MD Oslomouc, Czech Site investigator Data collection Republic David Školoudík, MD Ostrava, Czech Site principal Coordinated data Republic investigator collection for site Daniel Václavík, MD Ostrava, Czech Site investigator Data collection Republic Martin Kuliha, MD Ostrava, Czech Site investigator Data collection Republic Lucie Cabrejo, MD Paris, France Site investigator Data collection Céline Guidoux, MD Paris, France Site investigator Data collection Cristina Maria Paris, France Site investigator Data collection Hobeanu, MD Elena Meseguer, MD Paris, France Site investigator Data collection Henrich Audebert, Berlin, Germany Site principal Coordinated data MD investigator collection for site Daniel Menger, MD Berlin, Germany Site investigator Data collection Wolfgang Heide, MD Celle, Germany Site principal Coordinated data investigator collection for site Saskia Lipp, MD Celle, Germany Site investigator Data collection Huriye Ozalp, MD Celle, Germany Site investigator Data collection Christine Sctzmann, Celle, Germany Site investigator Data collection MD Christian Wiemar, Essen, Germany Site principal Coordinated data MD investigator collection for site Katharina Essen, Germany Site investigator Data collection Platzbecker, MD Peter Ringleb, MD Heidelberg, Germany Site principal Coordinated data investigator collection for site Martin Griebe, MD Mannheim, Germany Site investigator Data collection Katrin Knoll Olaf Mannheim, Germany Site investigator Data collection Willmann, MD Juergen Harmut Teupitz, Germany Site principal Coordinated data Faiss, MD investigator collection for site Susan Dillan, MD Teupitz, Germany Site investigator Data collection Anja Kobersteein, Teupitz, Germany Site investigator Data collection MD Katharina Krimmer, Teupitz, Germany Site investigator Data collection MD Sandra Tietz, MD Teupitz, Germany Site investigator Data collection Peter Wienecke, MD Teupitz, Germany Site investigator Data collection Gerhard Hamann, Wiessdbaden, Site principal Coordinated data MD Germany investigator collection for site Nico Burkhardt, MD Wiessdbaden, Site investigator Data collection Germany Martin Liebetrau, Wiessdbaden, Site investigator Data collection MD Germany Nadine Mueller, MD Wiessdbaden, Site investigator Data collection Germany Michaela Wagner, Wiessdbaden, Site investigator Data collection MD Germany D Strivastava, MD New Delhi, India Site principal Coordinated data investigator collection for site Peter Kelly, MD Dublin, Ireland Site principal Coordinated data investigator collection for site Aline Merwick, MD Dublin, Ireland Site investigator Data collection David Tanne, MD Tel Hashomer, Israel Site principal Coordinated data investigator collection for site Milena Cavazzuti, Emilia Romana, Italy Site principal Coordinated data MD investigator collection for site Sabrina Anticoli, MD Modena, Italy Site principal Coordinated data investigator collection for site Danilo Toni, MD Roma, Italy Site principal Coordinated data investigator collection for site Ken Nagata, MD Akita, Japan Site principal Coordinated data investigator collection for site Yasushi Okada, MD Fukuoka, Japan Site principal Data collection investigator Hiroshi Yamagami, Kobe, Japan Site principal Coordinated data MD investigator collection for site Kazuo Minematsu, Osaka, Japan Site principal Coordinated data MD investigator collection for site Jojo Nakagawara, Sapporo, Japan Site principal Coordinated data MD investigator collection for site Byung Chui Lee, MD Anyand-Si, Korea Site principal Coordinated data investigator collection for site Byung Woo Yoon, MD Anyabnd-Si, Korea Site principal Coordinated data investigator collection for site Ji Hoe Hoe, MD Seoul, Korea Site principal Coordinated data investigator collection for site Jong Moo Park, MD Seoul, Korea Site principal Coordinated data investigator collection for site Halim Abboud, MD Beirut, Lebanon Site principal Coordinated data investigator collection for site Salam Koussa, MD Beirut, Lebanon Site investigator Data collection Adnan Awada, MD Beirut, Lebanon Site investigator Data collection Kay Sin Tan, MD Kuala Lumpur, Site principal Coordinated data Malaysia investigator collection for site Antonio Arauz, MD Mexico-City, Mexico Site principal Coordinated data investigator collection for site Fernando Gongora- Monterrey, Mexico Site principal Coordinated data Rivera, MD investigator collection for site Adrian Infante Monterrey, Mexico Site investigator Data collection Valenzuela, MD Juan M Escamilla, Monterrey, Mexico Site investigator Data collection MD Patrica Canhao, MD Lisbon, Portugal Site principal Coordinated data investigator collection for site Ana Catarina Lisbon, Portugal Site investigator Data collection Fonseca, MD Manuel Correia, MD Porto, Portugal Site principal Coordinated data investigator collection for site Assuncao Tuna, MD Porto, Portugal Site investigator Data collection Nada Sternic, MD Belgrade, Serbia Site principal Coordinated data investigator collection for site Aleksandra Pavlovic Belgrade, Serbia Site investigator Data collection Mijajlovic, MD Beata Dupejova, MD Banska Bystrica, Site principal Coordinated data Slovakia investigator collection for site Jana Szedelyová, MD Banska Bystrica, Site investigator Data collection Slovakia Renata Smirkova, Krompachy, Slovakia Site principal Coordinated data MD investigator collection for site Tomas Segura, MD Albacete, Spain Site principal Coordinated data investigator collection for site Ana Rodgriguez, MD Barcelona, Spain Site principal Coordinated data investigator collection for site Yolanda Silva, MD Girona, Spain Site principal Coordinated data investigator collection for site Javier Tejada, MD Leon, Spain Site principal Coordinated data investigator collection for site Francisco Purroy, MD Lleida, Spain Site principal Coordinated data investigator collection for site Jaime Masjuan, MD Madrid, Spain Site principal Coordinated data investigator collection for site Jose Vivancos, MD Madrid, Spain Site principal Coordinated data investigator collection for site Ernest Palomeras, Mataro, Spain Site principal Coordinated data MD investigator collection for site Miguel Angel Sevilla, Spain Site principal Coordinated data Gamemro, MD investigator collection for site JF Arenillas, MD Valladolid, Spain Site principal Coordinated data investigator collection for site Anna Calleja, MD Valladolid, Spain Site investigator Data collection Esther Rojo, MD Valladolid, Spain Site investigator Data collection Alastair Buchan, MD Oxford, UK Site principal Coordinated data investigator collection for site Tsong Hai Lee, MD Kuei Shan, Taiwan Site principal Coordinated data investigator collection for site Ku Chou Chang, MD Kuei Shan, Taiwan Site principal Coordinated data investigator collection for site Yu-Ching Huang, MD Kuei Shan, Taiwan Site investigator Data collection Ruey-Tay Lin, MD Kaohsiung, Taiwan Site principal Coordinated data investigator collection for site Somsak Tiamkao, Khon Kaen, Taiwan Site principal Coordinated data MD investigator collection for site .

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