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Download Oral Program Cell Symposia: Human Immunity 2017 |Oral Program Sunday 22nd October 2017 11:00 Registration |Galleria Ground Floor 14:30-14:45 Welcome and Introduction |Kinnear Centre 203/205, 2nd Floor Session 1: Mapping the Human Immune System | Kinnear Centre 203/205 Session Chair: Tak Mak 14:45-15:30 Keynote Address: Mark Davis, Stanford University, USA [KYN.01] 15:30-16:00 D. Farber, Columbia University Medical Center, USA Human T cell compartmentalization, residence and maintenance in tissues [INV.01] 16:00-16:30 F. Ginhoux, Agency for Science, Technology and Research (A*STAR), Singapore Human dendritic cells: From development to functions [INV.02] 16:30-17:00 Refreshment Break | Husky Great Hall 101/103/105, Ground Floor 17:00-17:30 Federica Sallusto, IRB, University of Italian Switzerland, Switzerland [INV.03] 17:30-18:00 Yasmine Belkaid, NIAID/NIH, USA [INV.04] 18:00-21:00 Welcome Drinks Reception | Husky Great Hall 101/103/105, Ground Floor Monday 23rd October 2017 Session 2: Individuals & Populations: Understanding Variation in the Immune System | Kinnear Centre 203/205 Session Chair: Luis Barreiro 09:00-09:30 L. Barreiro, McGill University, Canada Genetic and evolutionary determinants of population differences in immune response to infections [INV.05] 09:30-10:00 M.G. Netea, Radboud University Medical Center, The Netherlands A systems approach to understand variability in innate immune responses [INV.06] 10:00-10:15 D.R. Simeonov*1, B.G. Gowen1, M. Boontanrart1, T.L. Roth1, J.D. Gagnon1, M.R. Mumbach2, A.T. Satpathy2, Y. Lee1, N.L. Bray1, A. Chan1, 1University of California, USA, 2Stanford University, USA Discovery of stimulation-responsive immune enhancers with CRISPR activation [ST.01] 10:15-10:30 Y. Liang*, L.C. Tsoi, X. Xing, W.R. Swindell, C.C. Berthier, P.W. Harms, J.T. Elder, J.J. Voorhees, J.M. Kahlenberg, J.E. Gudjonsson, University of Michigan, USA A VGLL3-regulated gene network as a promoter of sex-biased autoimmune diseases [ST.02] 10:30–11:00 Refreshment Break | Husky Great Hall 101/103/105 11:00-11:30 Eran Elinav, Weizmann Institute, Israel [INV.07] 11:30-12:00 L. Quintana-Murci, Center of Bioinformatics, Biostatistics and Integrative Biology, France Deciphering the contribution of genetic and evolutionary factors to population variation in immune responses to infection [INV.08] 12:00-12:15 M.L.T. Nguyen*1, D. Calderon2, J.V. Ribado2, A. Mezger2 ,3, B. Wu2, A. Kathiria2, L.A. Criswell1, W.J. Greenleaf2 ,4, J.K. Pritchard2, A. Marson1 ,4, 1University of California, USA, 2Stanford University, USA, 3Karolinska Institutet, Sweden, 4Chan Zuckerberg Biohub, USA An atlas of chromatin accessibility and transcriptome of the immune system [ST.03] 12:15-12:30 A. Olin, E. Henckel, K. Bohlin, P. Brodin*, Karolinska Institutet, Sweden Environmental imprinting on the human immune system during the first weeks of life [ST.04] 12:30-13:30 Lunch | Husky Great Hall 101/103/105 13:30-15:00 Poster Session | Husky Great Hall 101/103/105 Session 3: Learning Mechanism from Human Disease | Kinnear Centre 203/205 Session Chair: Adrian Hayday Adrian Hayday, The Francis Crick Institute, UK 15:00-15:30 Defects in AIRE cast new lights on autoimmune diseases and lymphocyte biology [INV.09] Mike Lenardo, NIAID/NIH, USA [INV.10] 15:30-16:00 G.E. Kaiko*, I. Chiang, T. Chiang-Lu, T.S. Stappenbeck, Washington University, USA 16:00-16:15 Reverse translation in IBD uncovers a coagulation-immune axis that drives colitis and predicts response to therapy [ST.05] Cell Symposia: Human Immunity 2017 |Oral Program 16:15-16:45 Refreshment Break| Husky Great Hall 101/103/105 J. Banchereau, The Jackson Laboratory for Genomic Medicine, USA 16:45-17:15 Expending genomic tools to assess human immunity [INV.11] A. Mortha1, 1University of Toronto, Canada, 2Mount Sinai Hospital, USA 17:15-17:30 Adaptive modulation of myeloid cell function resets the tissue-resident innate immune status of the human intestine [ST.06] E. Vivier, Aix-Marseille University, France 17:30-18:00 Functions of Innate Lymphoid Cells [INV.12] 19:00 Meet the Speakers Dinner | Mount View BBQ Tuesday 24th October 2017 Session 4: From Mechanism to Vaccines and Back | Kinnear Centre 203/205 Session Chair: Galit Alter 09:00-09:45 Keynote Address: Michel Nussenzweig, Rockefeller University, USA [KYN.02] 09:45-10:15 Galit Alter, Ragon Institute, USA Exploiting the adjuvanting effects of antibody glycosylation in vaccination [INV.13] 10:15-10:30 S.W. Scally*1, B. McLeod1 ,2, A. Bosch1, K. Miura3, S. Rämisch4, W. Schief4, D. Emerling5, P. Kellam6 ,7, C.R. King8, J- P. Julien1 ,2, 1The Hospital for Sick Children Research Institute, Canada, 2University of Toronto, Canada, 3National Institutes of Health, USA, 4The Scripps Research Institute, USA, 5Atreca, USA, 6Kymab Ltd, UK, 7Imperial College, UK, 8PATH Malaria Vaccine Initiative (MVI), USA Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25 [ST.07] 10:30–11:00 Refreshment Break | Husky Great Hall 101/103/105 11:00-11:30 Dan Barouch, Ragon Institute, USA [INV.14] 11:30-12:00 A. Lanzavecchia, IRB, University of Italian Switzerland, Switzerland Dissecting human antibody responses: Useful, basic and surprising findings [INV.15] 12:00-12:15 S. Fischinger*1 ,2, G. Alter1, H. Streeck2, 1Ragon Institute of MGH, MIT and Harvard, USA, 2University of Duisburg- Essen, Germany Antibody effector functions are tuned by prime/boost regimen in RV144 vaccine HIV-1 trial [ST.08] 12:15-12:30 L.E. Wagar*, A. Salahudeen, K.J. Jackson, K.M. Roskin, C.M. Constantz, C.J. Kuo, S.D. Boyd, M.M. Davis, Stanford University, USA A human in vitro germinal center model for vaccine testing [ST.09] 12:30-13:30 Lunch | Husky Great Hall 101/103/105 13:30-15:00 Poster Session | Husky Great Hall 101/103/105 Session 5: The Human Immune Response to Cancer | Kinnear Centre 203/205 Session Chair: Tania Watts Nicholas McGranahan, UCL Cancer Institute, UK 15:00-15:30 TRACERx: lung cancer evolution and immune escape [INV.16] Marco Colonna, Washington University, USA 15:30-16:00 Tailoring Natural Killer and ILC surveillance to the tumour microenvironment [INV.17] Y. Simoni*1, M. Fehlings1, C.Y. Loh1, I. Tan2, D. Tan2, E.W. Newell1, 1A*STAR SIgN, Singapore, 2Singapore General 16:00–16:15 Hospital, Singapore Profiling neoantigen-specific and bystander CD8 T cells infiltrating human tumor [ST.10] 16:15-16:45 Refreshment Break | Husky Great Hall 101/103/105 Matthew H. Spitzer, University of California, San Francisco, USA 16:45-17:15 Modeling system-wide immune responses in health and in cancer [INV.18] S.Q. Crome*1, L.T. Nguyen1, S. Lopez-Verges2, S.Y.C. Yang3 ,1, B. Martin1, P.A. Shaw1, H.K. Berman1, T.J. Pugh1 ,3, L.L. Lanier2, P.S. Ohashi1 ,3, 1University Health Network, Canada, 2University of California San Francisco, USA, 17:15-17:30 3University of Toronto, Canada A distinct innate lymphoid cell population regulates tumor-associated T cells [ST.11] Niroshana Anandasabapathy, Harvard Medical School, USA 17:30-18:00 Sensing tumor as tissue: New mechanisms supporting peripheral homeostasis are broadly co-opted in cancer [INV.19] 18:00–18:15 Closing Remarks .
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