Supply Guide Technology Snapshot

Orthopedic Cement

Description

Cements, whose main component is polymethyl methacrylate (PMMA), designed to produce a mechanical interlocking effect upon hardening. These cements usually consist of a powder (PMMA, prepolymerized PMMA, or methyl methacrylate co-polymer), a liquid (methylmethacrylate monomer), an initiator, an inhibitor, and a stabilizer that are mixed together. Orthopedic cements are typically applied as runny liquids that set up into a solid hardened material in a time period that can be tailored to the surgeon's needs. They are used in orthopedic procedures to anchor metal or plastic prosthetic devices to bone or used alone in the spine to treat osteoporotic compression fractures.

Popular Manufacturers and Products

Member Interest Key Considerations Top Manufacturers January 2020 - December 2020  Indicated use - Bone cement can be

Stryker used in joint replacement surgery, $13,867,091 Orthopaedics supporting fractured bones, treating vertebral fractures, and repairing craniofacial defects. DePuy Synthes $6,007,582  Antimicrobial properties - Bone cements Heraeus Medical can be loaded with an antimicrobial $3,785,185 LLC agent to help ward off infection. Selection of this criteria will depend upon surgeon and patient needs. Zimmer Biomet $3,529,465  Weight - What is the weight of the bone Medtronic cement? $3,433,539 Spinal and Bio  Self-contained - Is this product supplied so that mixing can occur without a Member Interest mixing bowl or transferring to a mixing Top Products device (material isn't exposed to air)? January 2020 - December 2020

Stryker Orthopaedics - 0607687000 - KIT BONE CEMENT POLYMETHYL METHACRYLATE BARIUM $6,256,648 SULPHATE RADIOPAQUE HIGH VISCOSITY…

Stryker Orthopaedics - 61911010 - CEMENT BONE POLYMETHYLMETACRYLATE $5,638,017 Key Questions Answered METHYLMETHACRYLATE STYRENE COPOLYMER…

Zimmer Biomet - 110035368 - Cement Bone  Who are the major players in this 40Gm Green Polymethyl Methacrylate Radiopaque $3,527,611 market? High Viscosity Nonantibiotic High Visibility Sterile

Medtronic Spinal and Bio - CX01B - KIT BONE  What are the top products among ECRI CEMENT POLYMETHYL METHACRYLATE METHYL $2,114,489 members? METHACRYLATE/STYRENE COPOLYMER…

Medtronic Spinal and Bio - C01B - KIT BONE  What were the product and pricing CEMENT POLYMETHYL METHACRYLATE METHYL $914,292 METHACRYLATE/STYRENE COPOLYMER… trends for between 2016 and 2020?

*Market data charts are based solely upon price points submitted to ECRI by our members. This data is not validated market share and is time sensitive.

Supply Guide Technology Snapshot | 1 Orthopedic Cement Feature Comparison for Top 5 Products

Medtronic Spinal and Biologics Div Medtronic Spinal and Biologics Div Medtronic Inc Medtronic Inc Stryker Orthopaedics Div Stryker KIT BONE CEMENT POLYMETHYL KIT BONE CEMENT POLYMETHYL Corp Stryker Orthopaedics Div Stryker METHACRYLATE METHYL METHACRYLATE METHYL KIT BONE CEMENT POLYMETHYL Corp METHACRYLATE/STYRENE METHACRYLATE/STYRENE METHACRYLATE BARIUM CEMENT BONE Zimmer Biomet COPOLYMER BARIUM SULPHATE COPOLYMER BARIUM SULPHATE SULPHATE RADIOPAQUE HIGH POLYMETHYLMETACRYLATE Cement Bone 40Gm Green BENZOYL PEROXIDE METHYL BENZOYL PEROXIDE METHYL VISCOSITY 18MIN WORKING METHYLMETHACRYLATE Polymethyl Methacrylate Manufacturer METHACRYLATE METHACRYLATE TIME 10MIN SETTING PHASE STYRENE COPOLYMER BARIUM Radiopaque High Viscosity HYDROQUINONE N N-DIMETHYL- HYDROQUINONE N N-DIMETHYL- TIME 70% PMMA INCLUDE SULFATE RADIOPAQUE FULL Nonantibiotic High Visibility P-TOLUIDINE TWO COMPONENT P-TOLUIDINE TWO COMPONENT AUTOPLEX SYSTEM STERILE DOSE DUAL PHASE IMPLANTABLE Sterile SYSTEM STERILE DISPOSABLE SYSTEM STERILE DISPOSABLE VERTAPLEX HV FOR FRACTURES SIMPLEX FOR ARTHROPLASTY KYPHON HV-R FOR KYPHON XPEDE FOR KYPHOPLASTY VERTEBROPLASTY PROCEDURE KYPHOPLASTY VERTEBROPLASTY KYPHOPLASTY VERTEBROPLASTY PROCEDURE PRO PR

CATALOG NUMBER C01B CX01BMT2 0607687000 61911010 110035368 UMDNS DESCRIPTION Orthopedic Cement Orthopedic Cement Orthopedic Cement Orthopedic Cement Orthopedic Cement Polymethyl methacrylate; Methyl Polymethyl methacrylate; Methyl Polymer (75% Methyl methacrylate/styrene copolymer; methacrylate/styrene copolymer; Polymethyl methacrylate; Barium methacrylate styrene copolymer, POWDER/DRY COMPONENT Polymethyl methacrylate Barium sulphate; Benzoyl Barium sulphate; Benzoyl Sulphate 15% Polymethyl methacrylate, peroxide peroxide 10% Barium sulphate) Liquid (Hydroquinone <1%, Methyl methacrylate; N,N- Methyl methacrylate; N,N- Methyl methacrylate 60-100%, LIQUID COMPONENT dimethyl-p-toluidine; dimethyl-p-toluidine; Not specified Not specified N,N-dimethyl-para-toluidine 1- Hydroquinone Hydroquinone 5%) ANTIBIOTIC NAME Not applicable Not applicable Not applicable Not applicable Not applicable COLOR NAME No No No No Green PACKAGING/PREPARATION Mixing kit Mixing kit Mixing kit Only cement Only cement COMPRESSIVE STRENGTH, MPa 111 111 Not specified Not specified Not specified BENDING STRENGTH, MPa Not specified Not specified Not specified Not specified Not specified MAXIMUM TEMPERATURE, °C Not specified Not specified Not specified Not specified Not specified MIXING TIME, min Not specified Not specified Not specified Not specified Not specified WAITING/DOUGHING TIME, min Not specified Not specified Not specified Not specified Not specified WORKING TIME, min 8.0 8.0 18.0 Not specified Not specified SETTING PHASE TIME, min 20.0 20.0 10.2 5.0-15.0 Not specified INDICATED FOR ARTHROPLASTY No No No Yes Yes INDICATED FOR FRACTURES Yes Yes Yes Yes No INDICATED FOR KYPHOPLASTY Yes Yes Yes No No INDICATED FOR VERTEBROPLASTY Yes Yes Yes No No ANTIMICROBIAL No No No No No WEIGHT 20 20 Not specified Not specified 40 SELF-CONTAINED No No No Not specified No VISCOSITY CLASSIFICATION High High High Medium High PMMA 100 100 70 100 100 DOES THIS CEMENT HAVE COLOR? No No No No Yes

Supply Guide Technology Snapshot | 2 Orthopedic Cement Price Trend

Median Price EA 2016 - 2020

$120

$100

$80

$60

$40

$20

$0 2016 2017 2018 2019 2020 Median Price $97 $80 $75 $75 $75

Disclaimer

The information provided in this report may be derived from a number of sources, including manufacturers, clinical users, and member facilities. We make every reasonable effort to ensure that it is up-to-date and verify it with the most knowledgeable sources. The contents of this document should not be regarded as a guarantee of the safety, performance, or cost-effectiveness of any equipment, device, or system. This document was created for ECRI member organizations and is copyrighted. It may not be shared with manufacturers or any third party without written permission from ECRI.

©2021 ECRI. All Rights Reserved. This material is confidential, and use of the copyright notice is not intended to suggest or imply that the material has been published or is available for public dissemination. This report was created for ECRI members and should not be reproduced or transmitted to third parties without written permission from ECRI.

Supply Guide Technology Snapshot | 3