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Press 'Ctrl' + 'F' on your keyboard Recommendations on the use of medication, developed by the Suffolk Drug & Therapeutics Committee, approved by the Clinical Priorities Group Shared care Drug or therapy area agreement, Prescriber A-Z links to electronic Medicines Decision Indication Safety NICE guidance pathways & rating Compendium eMC checklists Click below for: →Traffic Light rating explained →Prescriber rating explained Aclidinium bromide▼ ( Eklira For the treatment of chronic obstructive pulmonary disease (COPD) - 2nd line ( Judgement Primary Care A Genuair®) for patients who cannot use the tiotropium device effectively ) reserved Abiraterone (Zytigaq®) Hospital only As anti androgen - commissioned by NHSE Acitretin Hospital only Restricted to use by intergrated dermatology service and secondary care only N (TA231) Judgement Agomelatine (Valdoxan®) No prescribing Depression Terminated reserved Appraisal Aliskiren q (Rasilez®) No prescribing Hypertension Not acceptable Use in adults who have severe chronic hand eczema that is unresponsive to Judgement Alitretinoin (Toctino®) Hospital only N treatment with potent topical corticosteroids reserved (TA177) Alpha Interferon Hospital only Hepatitis C N (TA106) Alprostadil see erectile dysfunction (Caverject/Viridal®) Shared care Drug or therapy area agreement, Prescriber A-Z links to electronic Medicines Decision Indication Safety NICE guidance pathways & rating Compendium eMC checklists Hospital Amiodarone antiarrhythmia recommended expected to be for use as an antihypertensive in patients whose BP is not Amlodipine & valsartan Primary Care adequately controlled on amlodipine or valsartan monotherapy and as Nothing new (Exforge®) replacement for patients taking amlodipine and valsartan Anagrelide (Xagrid®) Hospital only essential thrombocythaemia, within clinical trials Anakinra (Kineret®) Hospital only rheumatoid arthritis if patient cannot take infliximab or etanercept N (CG79) Anti-cancer drugs including ORAL treatments - (NOW Hospital only chemotherapy COMMISSIONED BY NHSE) Anti-nauseants in Hospital only chemotherapy induced nausea chemotherapy Anti-TNF drugs Hospital only psoriasis Hospital For the treatment and secondary prevention of deep vein thrombosis and N Apixaban▼ (Eliquis®) recommended pulmonary embolism as per NICE TA 341 (TA341) For the prevention of venous thromboembolism in total hip or knee replacement N Apixaban▼ (Eliquis®) Hospital only in adults (TA245) For the prevention of stroke and systemic embolism in people with non-valvular N Apixaban▼ (Eliquis®) Primary Care atrial fibrillation with 1 or more risk factor such as; prior stroke or TIA, ≥75yrs, hypertension, diabetes mellitus or symptomatic heart failure (TA275) Apomorphine sublingual see erectile dysfunction Shared care Drug or therapy area agreement, Prescriber A-Z links to electronic Medicines Decision Indication Safety NICE guidance pathways & rating Compendium eMC checklists Hospital Hospital initiated and stabilised, then GP prescribed for schizophrenia Aripiprazole (Abilify®) N recommended including TA292 and TA213 (TA213) Atomoxetine (Strattera®) Shared care 2 Attention Deficit Hyperactivity Disorder (ADHD) in Adults N (CG72) Attention deficit hyperactivity disorder in children and adolescents (see also Atomoxetine (Strattera®) Shared care N 2 entry for ADHD) (TA98) Attention deficit hyperactivity Shared care all drug treatments N disorder ADHD in children 2 (CG72) Hospital Atypical neuroleptics Schizophrenia only (excl. clozapine, see separate entry) recommended Avanafil (Spedra▼) Primary Care For the treatment of erectile dysfunction in adult men Azelastine/Fluticasone Relief of symptoms of moderate–severe perennial allergic rhinitis for patients Primary Care Nothing new (Dymista®) who have failed to respond to a steroid nasal spray with the addition of an oral antihistamine . Treatment with Dymista® must be reviewed after 3 months and only continued for patients who are benefitting from it. Azathioprine Shared care 2 For the treatment of autoimmune conditions including systemic lupus erythematosus and vasculitis Azilsartan medoxomil No prescribing For the treatment of essential hypertension in adults Nothing new ▼(Edarbi®) B Becaplermin (Regranex®) Hospital only Diabetic foot ulcers Beta interferon No prescribing Patients not conforming to national MS trial criteria Shared care Drug or therapy area agreement, Prescriber A-Z links to electronic Medicines Decision Indication Safety NICE guidance pathways & rating Compendium eMC checklists Beta interferon Hospital only Patients conforming to national MS trial criteria Bexarotene (Targretin®) Hospital only see anti-cancer drugs Hospital Bicalutamide Early prostatic cancer recommended Brimonidine gel (Mirvaso®) No prescribing Mirvaso is indicated for the symptomatic treatment of facial erythema of rosacea in adult patients Hospital Brivaracetam (Briviact) recommended As an adjunctive therapy in the treatment of partial-onset seizures with or without secondary generalisation. Busulfan (Myleran®) Hospital only see anti-cancer drugs Cannabis sativa extract Hospital only pain relief in multiple sclerosis C (Sativex®) Canagliflozin (Invokana®q) Primary Care For use in patients with type 2 diabetes as per NICE TA 390 and NICE NG28 N (TA390) Capecitabine (Xeloda®) Hospital only see anti-cancer drugs Chlorambucil (Leukeran®) Hospital only see anti-cancer drugs i.e lamivudine, telbuvudine, telaprevir, ribavarin, interferon alfa etc…… please Chronic hepatitis B/C Hospital only phone the medicines management team if in any doubt Ciclosporin (oral) Shared care 2 immunosuppression related to dermatology, rheumatology and gastroenterology Shared care Drug or therapy area agreement, Prescriber A-Z links to electronic Medicines Decision Indication Safety NICE guidance pathways & rating Compendium eMC checklists Transplant immunosuppression - Do not prescribe for any new patients from Ciclosporin (oral) Shared care 2 01/04/13 as this is now commissioned by NHSE and should be supplied from the acute trust. must prescribe by brand name Hospital Severe keratitis in dry eye disease that has not responded to treatment with tear Ciclosporin eye drops N recommended substitutes (TA369) Possibly Cilostazol (Pletal®) No prescribing Intermittent claudication( for all new patients from July 2012 in line with TA223) N (TA223) helpful Possibly Cinacalcet (Mimpara®) Hospital only primary hyperparathyroidism or parathyroid carcinoma - helpful Possibly Cinacalcet (Mimpara®) Hospital only secondary hyperparathyroidism in end stage renal failure - N helpful (TA117) Hospital Clopidogrel for acute coronary syndrome; prescribe generically N recommended (TA80 & TA210) Clozapine (Clozaril® Hospital only schizophrenia Denzapine® Zaponex®) Colesevelam Hospital Possibly lipid-lowering (Cholestagel®) recommended helpful Collagenase clostridium for the treatment of Dupuytren's contracture in adult patients with a palpable Judgement Hospital only histolyticum ▼( Xiapex®) cord - reserved Cox II inhibitors Primary Care acute pain Cyclophosphamide Hospital only see anti-cancer drugs (Endoxana®) prevention of venous thromboembolic (VTE) events in adult patients who have Offers an Dabigatran (Pradaxa®) Hospital only undergone elective total hip replacement (THR) or total knee replacement (TKR) N D advantage surgery (TA157) Shared care Drug or therapy area agreement, Prescriber A-Z links to electronic Medicines Decision Indication Safety NICE guidance pathways & rating Compendium eMC checklists Prevention of stroke and systemic embolism in adult patients with nonvalvular atrial fibrillation with one or more of the following risk factors: Previous stroke, Dabigatran (Pradaxa®) Primary Care transient ischemic attack, or systemic embolism (SEE), Left ventricular ejection N fraction < 40 %,• Symptomatic heart failure, ≥ New York Heart Association (TA249) (NYHA) Class 2, Age ≥ 75 years,• Age ≥ 65 years associated with one of the following: diabetes mellitus, coronary artery disease, or hypertension. Hospital Treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE), and N Dabigatran (Pradaxa®) recommended prevention of recurrent DVT and PE in adults. (TA327) For the treatment of adult male patients with advanced hormone dependant Possibly Degarelix (Firmagon®) Hospital only N prostate cancer helpful (TA404) N Dapagliflozin (Forxiga®) Primary Care For use in patients with type 2 diabetes as per NICE TA 390 and NICE NG28 (TA390) Priligy is indicated for the treatment of premature ejaculation (PE) in adult men Dapoxetine (Priligy®) No prescribing aged 18 to 64 years. tumours; treatment of anaemia in adult cancer patients with solid tumours (non- Darbepoetin alfa (Araesp®) Hospital only N haematological malignancies) receiving chemotherapy (TA142) renal patients; treatment of anaemia in adult cancer patients with solid tumours Darbepoetin alfa (Araesp®) Hospital only (non-haematological malignancies) receiving chemotherapy - Dasatinib (Sprycel®) Hospital only see anti-cancer drugs Offers an Deferasirox q (Exjade®) Hospital only chronic iron overload advantage treatment of osteoporosis in postmenopausal women at increased risk of Denosumab q (Prolia®) Hospital only N Nothing new fractures as per NICE TA204 (TA204) Shared care Drug or therapy area agreement, Prescriber A-Z links to electronic Medicines Decision Indication Safety NICE guidance pathways & rating Compendium eMC checklists Hospital Depot antipsychotics schizophrenia
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