The Clinical Researc Unit 208 “Aetiology and Registration Sequelae of Periodontal Diseases ‐ Genetic, Cell German Society of Periodontology (DGP) Biological and Biomechanical Aspects” funded Neufferstrasse 1 by the German Research Foundation and the 93055 Regensburg Medical Faculty of the Universtity of International Symposium kindly invites you to the International Phone+49 (0)941 94 27 99‐0 Symposium in Bonn. The major goal of the www.dgparo.de of the Clinical Research Clinical Research Unit 208 is to improve the prevention, disease control and therapy of Location & Arrival Unit 208 periodontitis through a better understanding of Steigenberger Grandhotel Petersberg the causes and effects of periodontal diseases Petersberg „Aetiology and Sequelae and the regenerative processes in the involved 53639 Königswinter/Bonn, Germany of Periodontal Diseases ‐ tissues. The scientists of the Clinical Research http://www.steigenberger.com/en/Koenigswin Genetic, Cell Biological Unit, which are from the Dept. of ter_Bonn/arrivals Periodontology, Operative and Preventive and Biomechanical

Dentistry, the Dept. of Orthodontics, the Only 5 km from Königswinter and 15 km from Bonn, the Aspects“ Section of Oral Technology, the Dept. of Steigenberger Grandhotel Petersberg is situated on the hill of the same name in the Siebengebirge and welcomes one with a

Dermatology and Allergy, and the Dept. of splendid view of the Valley. /Bonn Airport is just September 17, 2010 Internal Medicine II, Cardiology, Pneumology, 25 minutes drive away. and Angiology (all from University of Bonn), the Hotel Petersberg Train Institute for Clinical Molecular Biology and the Königswinter‐Bonn 1st Dept. of General Internal Medicine of the The hotel is just 2.6 kilometre from the train station Koenigswinter. Germany University Hospital Schleswig‐Holstein Car (University of Kiel), and the Institute of Computational Science (University of Lugano) Input GPS: Ferdinand-Muelhens-Strasse Parking available will present their most recent research findings. Follow the signs to “Petersberg”. In addition, highly reputated researchers from Flight Sweden, The Netherlands, Greece, Spain, Airport Cologne/Bonn, Terminal 2: Finland, and Germany will provide you with Take bus N° 161 to train station Cologne/Porz. Change to regional train on track 2 direction Koenigswinter (length of trip excellent overviews on the current knowledge approx. 40 minutes). in various fields of periodontology, Airport Düsseldorf: orthodontics, biomechanics, genetics, Take regional train on track 4 to train station Cologne/Deutz immunology, and infection. (Arrival at track 8). Change to regional train on track 4 to Koenigswinter (length of trip approx. 60 minute

11:40 a.m. ‐ 12:10 p.m. 15:10 ‐ 15:30 p.m. Symposium Program Periodontitis as complex disease: genetics and Role of the insulin‐like growth factor‐system in the other factors periodontium under different stress conditions 8:30 ‐ 9:00 a.m. Bruno Loos, University of Amsterdam and VU University Project #7: Werner Götz, Birgit Rath‐Deschner Welcome and Introduction Amsterdam, Amsterdam, The Netherlands Department of Orthodontics, University of Bonn, Germany Søren Jepsen, Andreas Jäger, James Deschner 12:10 ‐ 12:30 p.m. 15:30 ‐ 15:50 p.m. 9:00 ‐ 9:30 a.m. The susceptibility genes of periodontitis – Role of human periodontal ligament cells and Host‐microbial interactions new and true parathyroid hormone in hard tissue repair Ingo Autenrieth, Project #3: Arne Schäfer1, Stefan Schreiber1, Søren Jepsen2 Project #8: Stefan Lossdörfer, Andreas Jäger Institute of Medical Microbiology and Hygiene, 1Institute of Clinical Molecularbiology and 1st Department Department of Orthodontics, University of Bonn, Germany University of Tübingen, Germany of Internal Medicine, University Hospital Schleswig‐ Holstein, University of Kiel 15:50 ‐ 16:20 p.m. 9:30 ‐ 9:50 a.m. 2Department of Periodontology, Operative and Preventive Break Role of distinct oral mucosal dendritic cell Dentistry, University of Bonn, Germany subsets in the pathophysiology of chronic 16:20 ‐ 16:50 p.m. periodontitis 12:30 ‐ 14:00 p.m. Periodontal infections and atherosclerosis Project #1: Jean‐Pierre Allam, Natalija Novak Lunch Mariano Sanz Department of Dermatology and Allergy, University of Bonn, University Complutense Madrid, Spain Germany 14:00 ‐ 14:30 p.m. The periodontal ligament under mechanical strain: 16:50 ‐ 17:20 p.m. 9:50 ‐ 10:20 a.m. cellular and molecular insights Oral, gastrointestinal and vascular NO Fibroblasts, integrins and the extracellular matrix Effie K. Basdra, Department of Orthodontics, metabolism – its relevance for the Thomas Krieg, Department of Dermatology, Aristotle University of Thessaloniki, Greece cardiovascular system University of Cologne, Germany Malte Kelm 14:30 ‐ 14:50 p.m. Department of Cardiology, Pneumology and Angiology, 10:20 ‐ 10:40 a.m. The effect of functional loading on periodontal University of Düsseldorf, Germany The role of antimicrobial peptides during wound healing in regenerative therapy with development and progression of periodontal 17:20 ‐ 17:40 p.m. enamel matrix derivatives Impact of periodontitis on vascular damage diseases Project #4: James Deschner Project #2: Henrik Dommisch, Søren Jepsen Department of Periodontology, Operative and Preventive and regeneration Department of Periodontology, Operative and Preventive Dentistry, University of Bonn, Germany Project #6: Nikos Werner Dentistry, University of Bonn, Germany Department of Internal Medicine II, Cardiology, 14:50 ‐ 15:10 p.m. Pneumology, and Angiology, University of Bonn, Germany 10:40 ‐ 11:10 a.m. Development of mathematical models and 17:40 ‐ 18:10 p.m. Break efficient algorithms to simulate the loading Oral health and pregnancy 11:10 ‐ 11:40 a.m. conditions of the periodontium in dental Jukka H. Meurman B cells in periodontitis: friends or enemies? biomechanics Institute of Dentistry, University of Helsinki, Finland Project #5: Christoph Bourauel1, Rolf Krause2 Tord Berglundh, Department of Periodontology, 1 18:10 ‐ 18:30 p.m. The Sahlgrenska Academy at Göteborg University, Göteborg, Oral Technology, University of Bonn, Germany 2 Concluding Remarks Sweden Institute of Computational Science, University of Lugano, James Deschner, Andreas Jäger, Søren Jepsen Switzerland