TH MILDRED SCHEEL CONFERENCE WWW.KREBSHILFE-MSCC.DE

PRELIMINARY PROGRAMME

Bonn, Maritim Hotel Kurt-Georg-Kiesinger-Allee 1 May 15 – 16, 2019

Organising Committee: Prof. Petra Boukamp Prof. Martin Eilers Prof. Simone Fulda Prof. Florian Greten Prof. Nadia Harbeck Prof. Bernhard Lüscher Prof. Christoph Plass Prof. Roland Schmid Prof. Evelin Schröck Programme – 9th MILDRED SCHEEL CANCER CONFERENCE Programme – 9th MILDRED SCHEEL CANCER CONFERENCE

Wednesday, May 15 Thursday, May 16

09:00 a.m. Opening Remarks / Welcome 08:30 a.m. Introduction Organising Committee Fritz Pleitgen, President German Cancer Aid Rainer Engers, German Cancer Society Session 3 Immunotherapy Simone Fulda, Organising Committee 09:15 a.m. Keynote Lecture – René Bernards – A one two punch model for 08:45 a.m. Thomas Tüting – Microenvironmental mechanisms of melanoma cancer therapy progression and therapy resistance 10:15 a.m. Introduction Organising Committee 09:15 a.m. Andrea Schietinger – Molecular programs defining tumor-specific T cell dysfunction and therapeutic reprogrammability Session 1 DNA Repair 09:45 a.m. Michael Hölzel – Modelling resistance to immunotherapy in melanoma 10:15 a.m. Coffee Break 10:30 a.m. Thierry Frébourg – Inherited due to DNA repair defects: Poster Session (Part IV) the paradigm of Li-Fraumeni syndrome 11:00 a.m. Andrea Ablasser – Intracellular DNA sensing in health and disease 11:00 a.m. Coffee Break 11:30 a.m. Abstract Talk 3 Poster Session (Part I) 11:45 a.m. Matthias Dobbelstein – Cancer vulnerabilities and the p53-Mdm2 system Session 4 Metabolism 12:15 p.m. Jiri Bartek – Stress-support pathways as cancer vulnerabilities: Mechanisms and opportunities for therapeutic intervention 11:45 a.m. Christian Frezza – Mitochondrial metabolism and cancer 12:45 p.m. Abstract Talk 1 12:15 p.m. Nika Danial – tba 01:00 p.m. Flash Talks I (short poster presentations, à 2 minutes) 12:45 p.m. Flash Talks III (short poster presentations, à 2 minutes) 01:25 p.m. Lunch Break & ’Meet the Expert‘* 01:10 p.m. Lunch Break & ’Meet the Expert‘* 02:45 p.m. Chris Lord – Synthetic lethality in cancer; challenges and opportunities 03:15 p.m. Karlene Cimprich – The causes and consequences of replication stress Session 5 Personalized Medicine 03:45 p.m. Abstract Talk 2 04:00 p.m. Flash Talks II (short poster presentations, à 2 minutes) 02:30 p.m. Poster Awards 04:25 p.m. Coffee Break 02:45 p.m. Hanno Glimm – Precision oncology – towards targeting functional and Poster Session (Part II) genetic heterogeneity 03:15 p.m. Özlem Türeci – Personalized Cancer Immunotherapy Session 2 Early Detection 03:45 p.m. Keynote Lecture – N.N. – tba 05:15 p.m. Klaus Pantel – Liquid biopsy – potential and challenges 04:45 p.m. Farewell / Concluding Remarks 05:45 p.m. Bernd Pichler – Multiparametric functional and metabolic imaging for 05:00 p.m. Snacks early cancer detection and profiling 06:15 p.m. Poster Session (Part III) Programme is subject to changes 07:00 p.m. Seated Dinner * Details will follow soon in internet

Organisation – 9th MILDRED SCHEEL CANCER CONFERENCE

Information and Registration

Location: Fellowships: Maritim Hotel Bonn For PhD and MD students and postdocs, a limited number of Kurt-Georg-Kiesinger-Allee 1 fellowships will be granted, with an announcement around 53175 Bonn, Germany 4 weeks prior to the conference. The fellowship will cover the travel expenses (limited to € 250,–) and accommodation How to reach the conference venue: during the conference for two nights. Accommodation costs Recommended railway station: ‚Central Station Bonn’ are limited to € 100,– p.p. per night. To obtain one of the OR ‚ICE-Station Siegburg’, from both stations take the ­ available fellowships please register for conference parti- U66 till the stop ‚Olof-Palme-Allee/Deutsche Telekom‘ cipation (price: € 120,–) and submit your poster abstract OR ‚Robert-Schuman-Platz‘. online until April 1st, 2019. Arriving by car/Taxi: Details navigation system Kurt-Georg-Kiesinger-Allee 1, 53175 Bonn. Poster Prize: Three posters will be selected from the programme Accommodation: committee for a poster prize of € 1.000,– each. All conference participants, except invited speakers, are ­responsible for making their own reservations. For hotel Registration/Registration fee: room reservation at the Maritim Hotel Bonn, please quote: The number of participants is limited to 230 persons. ‚Deutsche Krebshilfe‘. Registration fee: Maritim Hotel Bonn € 120,– Registration until April 1st, 2019 Tel.: +49 (0) 228/8108-777 € 145,– Registration from April 1st, 2019 E-Mail: [email protected] (incl. participation, drinks and meals during the conference). www.maritim.de Deadline for room reservation is April 13th, 2019. Cancellation until April 15th – the registration fee will be After April 13th the availability of rooms cannot be reimbursed. guaranteed! Different categories of rooms are available. Cancellation after April 15th – full payment of the registration For those wishing to arrange their own accommodation in fee, no reimbursement. Bonn, further information about travel, maps and tourist information can be found on the website: Please make your registration and submit your poster online: www.bonn.de or at the Tourist-Information Bonn www.krebshilfe-mscc.de E-Mail: [email protected]

Poster Session: All congress participants are invited to submit a poster for the Poster Sessions. Stiftung Deutsche Krebshilfe Conference Secretary Please upload your abstract for the poster session online, Buschstr. 32 Celsiusstr. 43 while booking your participation not later than April 1st, 53113 Bonn 53125 Bonn 2019: www.krebshilfe-mscc.de Phone: +49 (0) 228/72990-223 Phone: +49 (0) 177/7569009 Fax: +49 (0) 228/72990-11 Fax: +49 (0) 228/91937-23 Abstracts submitted later than April 1st cannot be included in E-Mail: [email protected] E-Mail: [email protected] the printed abstract brochure. www.krebshilfe.de www.beta-publishing.com