Running Head: RANDOMNESS AS INFERENCE 1 Subjective
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												Statistical Inferences Hypothesis Tests
STATISTICAL INFERENCES HYPOTHESIS TESTS Maªgorzata Murat BASIC IDEAS Suppose we have collected a representative sample that gives some information concerning a mean or other statistical quantity. There are two main questions for which statistical inference may provide answers. 1. Are the sample quantity and a corresponding population quantity close enough together so that it is reasonable to say that the sample might have come from the population? Or are they far enough apart so that they likely represent dierent populations? 2. For what interval of values can we have a specic level of condence that the interval contains the true value of the parameter of interest? STATISTICAL INFERENCES FOR THE MEAN We can divide statistical inferences for the mean into two main categories. In one category, we already know the variance or standard deviation of the population, usually from previous measurements, and the normal distribution can be used for calculations. In the other category, we nd an estimate of the variance or standard deviation of the population from the sample itself. The normal distribution is assumed to apply to the underlying population, but another distribution related to it will usually be required for calculations. TEST OF HYPOTHESIS We are testing the hypothesis that a sample is similar enough to a particular population so that it might have come from that population. Hence we make the null hypothesis that the sample came from a population having the stated value of the population characteristic (the mean or the variation). Then we do calculations to see how reasonable such a hypothesis is. We have to keep in mind the alternative if the null hypothesis is not true, as the alternative will aect the calculations. - 
												
												Higher-Order Asymptotics
Higher-Order Asymptotics Todd Kuffner Washington University in St. Louis WHOA-PSI 2016 1 / 113 First- and Higher-Order Asymptotics Classical Asymptotics in Statistics: available sample size n ! 1 First-Order Asymptotic Theory: asymptotic statements that are correct to order O(n−1=2) Higher-Order Asymptotics: refinements to first-order results 1st order 2nd order 3rd order kth order error O(n−1=2) O(n−1) O(n−3=2) O(n−k=2) or or or or o(1) o(n−1=2) o(n−1) o(n−(k−1)=2) Why would anyone care? deeper understanding more accurate inference compare different approaches (which agree to first order) 2 / 113 Points of Emphasis Convergence pointwise or uniform? Error absolute or relative? Deviation region moderate or large? 3 / 113 Common Goals Refinements for better small-sample performance Example Edgeworth expansion (absolute error) Example Barndorff-Nielsen’s R∗ Accurate Approximation Example saddlepoint methods (relative error) Example Laplace approximation Comparative Asymptotics Example probability matching priors Example conditional vs. unconditional frequentist inference Example comparing analytic and bootstrap procedures Deeper Understanding Example sources of inaccuracy in first-order theory Example nuisance parameter effects 4 / 113 Is this relevant for high-dimensional statistical models? The Classical asymptotic regime is when the parameter dimension p is fixed and the available sample size n ! 1. What if p < n or p is close to n? 1. Find a meaningful non-asymptotic analysis of the statistical procedure which works for any n or p (concentration inequalities) 2. Allow both n ! 1 and p ! 1. 5 / 113 Some First-Order Theory Univariate (classical) CLT: Assume X1;X2;::: are i.i.d. - 
												
												3 Autocorrelation
3 Autocorrelation Autocorrelation refers to the correlation of a time series with its own past and future values. Autocorrelation is also sometimes called “lagged correlation” or “serial correlation”, which refers to the correlation between members of a series of numbers arranged in time. Positive autocorrelation might be considered a specific form of “persistence”, a tendency for a system to remain in the same state from one observation to the next. For example, the likelihood of tomorrow being rainy is greater if today is rainy than if today is dry. Geophysical time series are frequently autocorrelated because of inertia or carryover processes in the physical system. For example, the slowly evolving and moving low pressure systems in the atmosphere might impart persistence to daily rainfall. Or the slow drainage of groundwater reserves might impart correlation to successive annual flows of a river. Or stored photosynthates might impart correlation to successive annual values of tree-ring indices. Autocorrelation complicates the application of statistical tests by reducing the effective sample size. Autocorrelation can also complicate the identification of significant covariance or correlation between time series (e.g., precipitation with a tree-ring series). Autocorrelation implies that a time series is predictable, probabilistically, as future values are correlated with current and past values. Three tools for assessing the autocorrelation of a time series are (1) the time series plot, (2) the lagged scatterplot, and (3) the autocorrelation function. 3.1 Time series plot Positively autocorrelated series are sometimes referred to as persistent because positive departures from the mean tend to be followed by positive depatures from the mean, and negative departures from the mean tend to be followed by negative departures (Figure 3.1). - 
												
												The Focused Information Criterion in Logistic Regression to Predict Repair of Dental Restorations
THE FOCUSED INFORMATION CRITERION IN LOGISTIC REGRESSION TO PREDICT REPAIR OF DENTAL RESTORATIONS Cecilia CANDOLO1 ABSTRACT: Statistical data analysis typically has several stages: exploration of the data set; deciding on a class or classes of models to be considered; selecting the best of them according to some criterion and making inferences based on the selected model. The cycle is usually iterative and will involve subject-matter considerations as well as statistical insights. The conclusion reached after such a process depends on the model(s) selected, but the consequent uncertainty is not usually incorporated into the inference. This may lead to underestimation of the uncertainty about quantities of interest and overoptimistic and biased inferences. This framework has been the aim of research under the terminology of model uncertainty and model averanging in both, frequentist and Bayesian approaches. The former usually uses the Akaike´s information criterion (AIC), the Bayesian information criterion (BIC) and the bootstrap method. The last weigths the models using the posterior model probabilities. This work consider model selection uncertainty in logistic regression under frequentist and Bayesian approaches, incorporating the use of the focused information criterion (FIC) (CLAESKENS and HJORT, 2003) to predict repair of dental restorations. The FIC takes the view that a best model should depend on the parameter under focus, such as the mean, or the variance, or the particular covariate values. In this study, the repair or not of dental restorations in a period of eighteen months depends on several covariates measured in teenagers. The data were kindly provided by Juliana Feltrin de Souza, a doctorate student at the Faculty of Dentistry of Araraquara - UNESP. - 
												
												The Bayesian Approach to Statistics
THE BAYESIAN APPROACH TO STATISTICS ANTHONY O’HAGAN INTRODUCTION the true nature of scientific reasoning. The fi- nal section addresses various features of modern By far the most widely taught and used statisti- Bayesian methods that provide some explanation for the rapid increase in their adoption since the cal methods in practice are those of the frequen- 1980s. tist school. The ideas of frequentist inference, as set out in Chapter 5 of this book, rest on the frequency definition of probability (Chapter 2), BAYESIAN INFERENCE and were developed in the first half of the 20th century. This chapter concerns a radically differ- We first present the basic procedures of Bayesian ent approach to statistics, the Bayesian approach, inference. which depends instead on the subjective defini- tion of probability (Chapter 3). In some respects, Bayesian methods are older than frequentist ones, Bayes’s Theorem and the Nature of Learning having been the basis of very early statistical rea- Bayesian inference is a process of learning soning as far back as the 18th century. Bayesian from data. To give substance to this statement, statistics as it is now understood, however, dates we need to identify who is doing the learning and back to the 1950s, with subsequent development what they are learning about. in the second half of the 20th century. Over that time, the Bayesian approach has steadily gained Terms and Notation ground, and is now recognized as a legitimate al- ternative to the frequentist approach. The person doing the learning is an individual This chapter is organized into three sections. - 
												
												The Method of Maximum Likelihood for Simple Linear Regression
08:48 Saturday 19th September, 2015 See updates and corrections at http://www.stat.cmu.edu/~cshalizi/mreg/ Lecture 6: The Method of Maximum Likelihood for Simple Linear Regression 36-401, Fall 2015, Section B 17 September 2015 1 Recapitulation We introduced the method of maximum likelihood for simple linear regression in the notes for two lectures ago. Let's review. We start with the statistical model, which is the Gaussian-noise simple linear regression model, defined as follows: 1. The distribution of X is arbitrary (and perhaps X is even non-random). 2. If X = x, then Y = β0 + β1x + , for some constants (\coefficients", \parameters") β0 and β1, and some random noise variable . 3. ∼ N(0; σ2), and is independent of X. 4. is independent across observations. A consequence of these assumptions is that the response variable Y is indepen- dent across observations, conditional on the predictor X, i.e., Y1 and Y2 are independent given X1 and X2 (Exercise 1). As you'll recall, this is a special case of the simple linear regression model: the first two assumptions are the same, but we are now assuming much more about the noise variable : it's not just mean zero with constant variance, but it has a particular distribution (Gaussian), and everything we said was uncorrelated before we now strengthen to independence1. Because of these stronger assumptions, the model tells us the conditional pdf 2 of Y for each x, p(yjX = x; β0; β1; σ ). (This notation separates the random variables from the parameters.) Given any data set (x1; y1); (x2; y2);::: (xn; yn), we can now write down the probability density, under the model, of seeing that data: n n (y −(β +β x ))2 Y 2 Y 1 − i 0 1 i p(yijxi; β0; β1; σ ) = p e 2σ2 2 i=1 i=1 2πσ 1See the notes for lecture 1 for a reminder, with an explicit example, of how uncorrelated random variables can nonetheless be strongly statistically dependent. - 
												
												Use of the Kurtosis Statistic in the Frequency Domain As an Aid In
lEEE JOURNALlEEE OF OCEANICENGINEERING, VOL. OE-9, NO. 2, APRIL 1984 85 Use of the Kurtosis Statistic in the FrequencyDomain as an Aid in Detecting Random Signals Absmact-Power spectral density estimation is often employed as a couldbe utilized in signal processing. The objective ofthis method for signal ,detection. For signals which occur randomly, a paper is to compare the PSD technique for signal processing frequency domain kurtosis estimate supplements the power spectral witha new methodwhich computes the frequency domain density estimate and, in some cases, can be.employed to detect their presence. This has been verified from experiments vith real data of kurtosis (FDK) [2] forthe real and imaginary parts of the randomly occurring signals. In order to better understand the detec- complex frequency components. Kurtosis is defined as a ratio tion of randomlyoccurring signals, sinusoidal and narrow-band of a fourth-order central moment to the square of a second- Gaussian signals are considered, which when modeled to represent a order central moment. fading or multipath environment, are received as nowGaussian in Using theNeyman-Pearson theory in thetime domain, terms of a frequency domain kurtosis estimate. Several fading and multipath propagation probability density distributions of practical Ferguson [3] , has shown that kurtosis is a locally optimum interestare considered, including Rayleigh and log-normal. The detectionstatistic under certain conditions. The reader is model is generalized to handle transient and frequency modulated referred to Ferguson'swork for the details; however, it can signals by taking into account the probability of the signal being in a be simply said thatit is concernedwith detecting outliers specific frequency range over the total data interval. - 
												
												Scalable and Robust Bayesian Inference Via the Median Posterior
Scalable and Robust Bayesian Inference via the Median Posterior CS 584: Big Data Analytics Material adapted from David Dunson’s talk (http://bayesian.org/sites/default/files/Dunson.pdf) & Lizhen Lin’s ICML talk (http://techtalks.tv/talks/scalable-and-robust-bayesian-inference-via-the-median-posterior/61140/) Big Data Analytics • Large (big N) and complex (big P with interactions) data are collected routinely • Both speed & generality of data analysis methods are important • Bayesian approaches offer an attractive general approach for modeling the complexity of big data • Computational intractability of posterior sampling is a major impediment to application of flexible Bayesian methods CS 584 [Spring 2016] - Ho Existing Frequentist Approaches: The Positives • Optimization-based approaches, such as ADMM or glmnet, are currently most popular for analyzing big data • General and computationally efficient • Used orders of magnitude more than Bayes methods • Can exploit distributed & cloud computing platforms • Can borrow some advantages of Bayes methods through penalties and regularization CS 584 [Spring 2016] - Ho Existing Frequentist Approaches: The Drawbacks • Such optimization-based methods do not provide measure of uncertainty • Uncertainty quantification is crucial for most applications • Scalable penalization methods focus primarily on convex optimization — greatly limits scope and puts ceiling on performance • For non-convex problems and data with complex structure, existing optimization algorithms can fail badly CS 584 [Spring 2016] - - 
												
												1 Estimation and Beyond in the Bayes Universe
ISyE8843A, Brani Vidakovic Handout 7 1 Estimation and Beyond in the Bayes Universe. 1.1 Estimation No Bayes estimate can be unbiased but Bayesians are not upset! No Bayes estimate with respect to the squared error loss can be unbiased, except in a trivial case when its Bayes’ risk is 0. Suppose that for a proper prior ¼ the Bayes estimator ±¼(X) is unbiased, Xjθ (8θ)E ±¼(X) = θ: This implies that the Bayes risk is 0. The Bayes risk of ±¼(X) can be calculated as repeated expectation in two ways, θ Xjθ 2 X θjX 2 r(¼; ±¼) = E E (θ ¡ ±¼(X)) = E E (θ ¡ ±¼(X)) : Thus, conveniently choosing either EθEXjθ or EX EθjX and using the properties of conditional expectation we have, θ Xjθ 2 θ Xjθ X θjX X θjX 2 r(¼; ±¼) = E E θ ¡ E E θ±¼(X) ¡ E E θ±¼(X) + E E ±¼(X) θ Xjθ 2 θ Xjθ X θjX X θjX 2 = E E θ ¡ E θ[E ±¼(X)] ¡ E ±¼(X)E θ + E E ±¼(X) θ Xjθ 2 θ X X θjX 2 = E E θ ¡ E θ ¢ θ ¡ E ±¼(X)±¼(X) + E E ±¼(X) = 0: Bayesians are not upset. To check for its unbiasedness, the Bayes estimator is averaged with respect to the model measure (Xjθ), and one of the Bayesian commandments is: Thou shall not average with respect to sample space, unless you have Bayesian design in mind. Even frequentist agree that insisting on unbiasedness can lead to bad estimators, and that in their quest to minimize the risk by trading off between variance and bias-squared a small dosage of bias can help. - 
												
												A Review of Graph and Network Complexity from an Algorithmic Information Perspective
entropy Review A Review of Graph and Network Complexity from an Algorithmic Information Perspective Hector Zenil 1,2,3,4,5,*, Narsis A. Kiani 1,2,3,4 and Jesper Tegnér 2,3,4,5 1 Algorithmic Dynamics Lab, Centre for Molecular Medicine, Karolinska Institute, 171 77 Stockholm, Sweden; [email protected] 2 Unit of Computational Medicine, Department of Medicine, Karolinska Institute, 171 77 Stockholm, Sweden; [email protected] 3 Science for Life Laboratory (SciLifeLab), 171 77 Stockholm, Sweden 4 Algorithmic Nature Group, Laboratoire de Recherche Scientifique (LABORES) for the Natural and Digital Sciences, 75005 Paris, France 5 Biological and Environmental Sciences and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal 23955, Saudi Arabia * Correspondence: [email protected] or [email protected] Received: 21 June 2018; Accepted: 20 July 2018; Published: 25 July 2018 Abstract: Information-theoretic-based measures have been useful in quantifying network complexity. Here we briefly survey and contrast (algorithmic) information-theoretic methods which have been used to characterize graphs and networks. We illustrate the strengths and limitations of Shannon’s entropy, lossless compressibility and algorithmic complexity when used to identify aspects and properties of complex networks. We review the fragility of computable measures on the one hand and the invariant properties of algorithmic measures on the other demonstrating how current approaches to algorithmic complexity are misguided and suffer of similar limitations than traditional statistical approaches such as Shannon entropy. Finally, we review some current definitions of algorithmic complexity which are used in analyzing labelled and unlabelled graphs. This analysis opens up several new opportunities to advance beyond traditional measures. - 
												
												Introduction to Bayesian Inference and Modeling Edps 590BAY
Introduction to Bayesian Inference and Modeling Edps 590BAY Carolyn J. Anderson Department of Educational Psychology c Board of Trustees, University of Illinois Fall 2019 Introduction What Why Probability Steps Example History Practice Overview ◮ What is Bayes theorem ◮ Why Bayesian analysis ◮ What is probability? ◮ Basic Steps ◮ An little example ◮ History (not all of the 705+ people that influenced development of Bayesian approach) ◮ In class work with probabilities Depending on the book that you select for this course, read either Gelman et al. Chapter 1 or Kruschke Chapters 1 & 2. C.J. Anderson (Illinois) Introduction Fall 2019 2.2/ 29 Introduction What Why Probability Steps Example History Practice Main References for Course Throughout the coures, I will take material from ◮ Gelman, A., Carlin, J.B., Stern, H.S., Dunson, D.B., Vehtari, A., & Rubin, D.B. (20114). Bayesian Data Analysis, 3rd Edition. Boco Raton, FL, CRC/Taylor & Francis.** ◮ Hoff, P.D., (2009). A First Course in Bayesian Statistical Methods. NY: Sringer.** ◮ McElreath, R.M. (2016). Statistical Rethinking: A Bayesian Course with Examples in R and Stan. Boco Raton, FL, CRC/Taylor & Francis. ◮ Kruschke, J.K. (2015). Doing Bayesian Data Analysis: A Tutorial with JAGS and Stan. NY: Academic Press.** ** There are e-versions these of from the UofI library. There is a verson of McElreath, but I couldn’t get if from UofI e-collection. C.J. Anderson (Illinois) Introduction Fall 2019 3.3/ 29 Introduction What Why Probability Steps Example History Practice Bayes Theorem A whole semester on this? p(y|θ)p(θ) p(θ|y)= p(y) where ◮ y is data, sample from some population. - 
												
												What Is Statistic?
What is Statistic? OPRE 6301 In today’s world. ...we are constantly being bombarded with statistics and statistical information. For example: Customer Surveys Medical News Demographics Political Polls Economic Predictions Marketing Information Sales Forecasts Stock Market Projections Consumer Price Index Sports Statistics How can we make sense out of all this data? How do we differentiate valid from flawed claims? 1 What is Statistics?! “Statistics is a way to get information from data.” Statistics Data Information Data: Facts, especially Information: Knowledge numerical facts, collected communicated concerning together for reference or some particular fact. information. Statistics is a tool for creating an understanding from a set of numbers. Humorous Definitions: The Science of drawing a precise line between an unwar- ranted assumption and a forgone conclusion. The Science of stating precisely what you don’t know. 2 An Example: Stats Anxiety. A business school student is anxious about their statistics course, since they’ve heard the course is difficult. The professor provides last term’s final exam marks to the student. What can be discerned from this list of numbers? Statistics Data Information List of last term’s marks. New information about the statistics class. 95 89 70 E.g. Class average, 65 Proportion of class receiving A’s 78 Most frequent mark, 57 Marks distribution, etc. : 3 Key Statistical Concepts. Population — a population is the group of all items of interest to a statistics practitioner. — frequently very large; sometimes infinite. E.g. All 5 million Florida voters (per Example 12.5). Sample — A sample is a set of data drawn from the population.