Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_006229535Cyc: Streptomyces rimosus WT5260 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari putrescine spermidine phosphate a dipeptide a sulfonate phosphate phosphate a metal cation glycine betaine glycine betaine glycine betaine glycine betaine hydrogencarbonate D-gluconate (S)-lactate nitrate phosphate a dipeptide citrate pro pro pro pro nitrate predicted predicted predicted ABC ABC ABC transporter RS32680 RS14355 RS24980 RS33375 RS37135 RS25690 RS28500 RS38345 RS25335 RS31720 RS16730 RS27230 RS11775 transporter transporter of spermidine/ of phosphate of a dipeptide putrescine a metal cation glycine betaine glycine betaine glycine betaine glycine betaine a sulfonate phosphate phosphate D-gluconate (S)-lactate nitrate a dipeptide citrate pro pro pro pro hydrogencarbonate phosphate nitrate putrescine phosphate a dipeptide spermidine

Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis Inorganic Nutrient Metabolism Degradation/ Utilization/ undecaprenyl- a mature α ε 3-benzyl-3,6 - (S)-2-oxo-4- a (5Z)-3- Assimilation - Other a purine 4-hydroxy-2-oxoglutarate N ,N -diacetyl-lysyl- an N-modified a 3-oxopimeloyl- a ribonucleoside cob(II)yrinate a,c- factor 420 biosynthesis Fermentation mixed acid fermentation superpathway of sulfate assimilation diphospho-N- cob(II)yrinate peptidoglycan KDGP bis(cysteinylglycine) hydroxy-4-carboxy- a 3-oxoicosanoyl-[acp] a protein oxotetracos- met an arachidoyl-[acp] cob(II)yrinate a,c-diamide [2Fe-2S] iron-sulfur flavin biosynthesis I (bacteria and plants) adenosylcobinamide-GDP mycothiol biosynthesis NAD biosynthesis from 2-amino- adenosylcobalamin biosynthesis Aminoacyl-tRNA Charging selenate reduction nitrate reduction V (assimilatory) urea cycle acrylonitrile ribonucleoside ATP D-alanyl-D-alanine aminoacyl-[tRNA] [acp] methyl ester diphosphate ITP dGDP diamide biosynthesis I 5-methylbenzimidazolyl benzimidazolyl adenosylcobamide and cysteine biosynthesis dimethyl sulfide assimilatory UDP-N-acetyl- adenosylcobinamide a,c-diamide bifunctional 4-hydroxy- - 6-(hydroxymethyl) 5-ureidoimidazoline 5-enoyl-[acp] biosynthesis II (late salvage from cobinamide I acetylmuramoyl- (meso- D-alanyl-D-alanine bifunctional aminoacyl-tRNA 2-oxo-4-hydroxy- 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- vitamin B12- ATP-dependent Clp 3-oxoacyl- amino-acid N- enoyl-ACP (early cobalt insertion) cluster biosynthesis adenosylcobamide biosynthesis biosynthesis from 3-carboxymuconate semialdehyde from adenosylcobinamide-GDP I degradation sulfate reduction III degradation I γ α 5'-triphosphate bifunctional cob(I)yrinic acid -diketopiperazinemembrane RdgB/HAM1 family non- vitamin B12- 3-phospho- L-alanyl- -D- -D-glucosamine diaminopimelate 2-oxoglutarate aldolase/ carboxypeptidase/ 4-hydroxy-2- hydrolase: carrier-protein] carrier-protein] dependent protease proteolytic: [acyl-carrier- acetyltransferase: reductase cobalt incorporation) from adenosylcobinamide-GDP adenosylcobinamide-GDP D-glucopyranose 2-amino-3- ARP tRNA charging phosphoenolpyruvate II (oxidation) selenate lytic dipeptidase: 4-carboxy-5- canonical purine NTP dependent gln nitrate arg glutamyl-L-lysyl- UDP-N- adenosylcobinamide a,c-diamide containing) 2-dehydro-3-deoxy- D-alanyl-D-alanine- reductase: fabG reductase: fabG CTZ40_RS17065 FabI: fabI uroporphyrinogen-III GTP cob(II)inamide 6-phosphate 5,6-dimethylbenzimidazole glutaminyl-tRNA sulfate D-glycerate acrylonitrile transglycosylase oxoglutarate CTZ40_RS16170 ureidoimidazoline ribonucleotide pyrophosphatase: rdgB CTZ40_RS26965 protein] uroporphyrinogen-III L-cysteine desulfurase carboxymuconate- arginine-- sulfate sulfate acetylglucosamine- kinase/ adenosyltransferase: phosphogluconate CTZ40_RS24825 ribonucleotide sulfate RS36720 sulfate bifunctional 5-methylbenzimidazole NaMN benzimidazole cob(I)yrinic acid 7,8-didemethyl- nicotinate-nucleotide-- biosynthesis via transamidation phosphoglycerate dimethyl sulfide D-alanyl-D-alanine domain-containing endopeptidase: dacB aldolase/2- aminoacyl-tRNA decarboxylase: uraD 3-oxoacyl-ACP 3-oxoacyl-ACP reductase: CTZ40_RS26970 reductase: bifunctional enoyl-ACP bifunctional inositol-3- 6-semialdehyde pyruvate kinase: pyk phosphoenolpyruvate sulfate adenylyltransferase: respiratory sulfate adenosylcobinamide- cobO aldolase: eda membrane nucleoside triphosphate reductase: uroporphyrinogen-III nicotinate-nucleotide-- nicotinate-nucleotide-- a,c-diamide 8-hydroxy-5- dimethylbenzimidazole tRNA ligase: -N-acetylmuramyl- penicillin- dehydro-3-deoxy- hydrolase: reductase: reductase: CTZ40_RS10085 ATP-dependent fabG glutamate N- reductase cysteine bifunctional phosphate adenylyltransferase: dehydrogenase: CTZ40_RS08230 nitrate reductase: adenylyltransferase: protein: 2-oxo-4-hydroxy- pyrophosphohydrolase: CTZ40_RS10085 uroporphyrinogen-III dimethylbenzimidazole dimethylbenzimidazole deazariboflavin CTZ40_RS00565 pyruvate kinase: pyk carboxylase: (pentapeptide) phosphate cob(I)yrinic acid bifunctional 4-hydroxy- binding dipeptidase: CTZ40_RS28785 CTZ40_RS28785 FabI: fabI C-methyltransferase/ desulfurase: 3,4-dihydroxy- adenosyltransferase: synthase: phosphoribosyltransferase: glu CTZ40_RS11530 CTZ40_RS36830 CTZ40_RS08230 acrylamide CTZ40_RS14195 phosphogluconate CTZ40_RS24375 3-benzyl-3,6 - 4-carboxy-5- ribonucleoside- Clp protease 3-oxoacyl-ACP acetyltransferase/ C-methyltransferase/ phosphoribosyltransferase: phosphoribosyltransferase: quinolinate CTZ40_RS24360 CTZ40_RS08230 sulfate pyrophosphoryl- guanylyltransferase: a,c-diamide a mature an N-modified an uncharged CTZ40_RS00370 a (3R)-3-hydroxypimeloyl- a (3R)-3- CTZ40_RS24475 ribonucleoside- a (2E)-icos- uroporphyrinogen- CTZ40_RS12430 CTZ40_RS19545 synthase: cobT arginine- dimethyl sulfoxide ammonium 2-oxoglutarate aldolase/ protein aldolase: eda bis(cysteinyl)- 6- diphosphate proteolytic subunit: reductase: amino-acid uroporphyrinogen- CTZ40_RS11720 2-butanone- sulfate adenylyltransferase narH narI sulfate undecaprenol N- CTZ40_RS30025 peptidoglycan [+ 3 isozymes] tRNA ureidoimidazoline IMP diphosphate III synthase: cobT cobT CTZ40_RS23000 -tRNA pyruvate 3-phosphooxypyruvate amidase: Aldehyde a purine adenosyl- adenosyltransferase: 2-dehydro-3-deoxy- 2: mrdA amino acid gly [acp] methyl ester hydroxyicosanoyl-[acp] CTZ40_RS37290 CTZ40_RS28785 acetyltransferase 2-enoyl-[acp] [+ 2 isozymes] 4-phosphate cob(I)yrinic acid carboxylating nicotinate-nucleotide-- arg subunit CysD: cysD CTZ40_RS36860 adenylyltransferase with (L-alanyl- a mature bifunctional (hydroxymethyl) decarboxylase: reductase: a (3R,5Z)-3- III synthase: nicotinate-nucleotide-- adenylyltransferase adenosine 5'- Degradation acetylglucosamine ribonucleoside cobinamide CTZ40_RS12430 phosphogluconate Nα,Nε-diacetyl- reductase: CTZ40_RS21400 synthase/GTP nicotinate-nucleotide-- a,c-diamide Ins(3)P UDP-N-acetyl- 5-amino-5-(4- dimethylbenzimidazole ligase: oxaloacetate narH narI argininosuccinate glutamine- CTZ40_RS32760 adenosyl-cob(III) γ -diketopiperazine CTZ40_RS14975 CTZ40_RS13265 a peptide hydroxytetracos- ArgJ: argJ CTZ40_RS21400 nicotinate- subunit CysD: cysD 3-phosphoserine/ subunit CysD: cysD transferase: triphosphate -D-glutamyl- peptidoglycan D-ala 4-hydroxy-2- CTZ40_RS13265 an S-sulfanyl-[L- dimethylbenzimidazole dimethylbenzimidazole α-D-glucosamine hydroxybenzyl)- argS an L-arginyl- phosphoselenate hydrolyzing [+ 6 isozymes] 5'-diphosphate phosphate yrinate a,c-diamide aldolase: eda lysyl-D-alanine CTZ40_RS13270 N-acetyl-L- uroporphyrinogen-III cyclohydrolase II: adenosyltransferase: nucleotide phosphoribosyltransferase: gln D-lactate phosphohydroxythreonine [+ 2 isozymes] lyase: argH APS methylglyoxal CTZ40_RS12235 meso-2,6- strand (non- oxoglutarate (S)-(+)-allantoin a 2'- 5-enoyl-[acp] CTZ40_RS13270 uroporphyrinogen-III cysteine desulfurase] phosphoribosyltransferase: phosphoribosyltransferase: 6-(D-ribitylimino) Arg an L-glutamyl- malate carbamoyl- glyoxylate methionine C-methyltransferase: CTZ40_RS34485 [corrinoid cobO diphosphorylase: cobT [tRNA ] dehydrogenase: vanH APS transaminase: serC L-arginino- diaminopimeloyl- reducing terminus) pyruvate aldolase/2- deoxyribonucleoside Arg Gln formate C- dehydrogenase: dimethyl sulfone L-ornithine acrylate degradation I cobA C-methyltransferase: 2,5-diamino-6- cobT cobT D-inositol-3-phosphate -5,6-dihydrouracil α-ribazole a tRNA [tRNA ] nitrite succinate phosphate phosphoadenylyl- undecaprenyldiphospho- GDP 5-methylbenzimidazole benzimidazole adenosyltranferase]- CTZ40_RS17090 phosphoenol Asp-tRNA(Asn) acetyltransferase: pflB phosphoserine D-alanine) dehydro-3-deoxy- 5'-diphosphate precorrin-1 cobA (5-phospho-D- glycosyltransferase: 7,8-didemethyl- 5'-phosphate CTZ40_RS15280 adenylyl- synthase: sulfate reductase: muramoylpentapeptide beta-N- precorrin-1 ribotide phosphate ribotide phosphate cob(II)inamide pyruvate /Glu-tRNA(Gln) Asp-tRNA(Asn) transaminase: dimethyl sulfone argininosuccinate methylglyoxal tetrapeptide phosphogluconate ribosylamino) mshA NaMN 8-hydroxy-5- (R)-lactate NAD-dependent sulfate selenite carA carB CTZ40_RS08215 ditrans,octacisacetylglucosaminyltransferase:- an S-sulfanyl-[cysteine adenosylcobinamide- amidotransferase: /Glu-tRNA(Gln) formate acetyl-CoA serC monooxygenase synthase: lactoylglutathione aldolase: eda bifunctional pyrimidin- adenosylcobinamide- adenosylcobinamide- 2-phospho-L-lactate deazariboflavin malic enzyme: kinase: undecaprenyldiphospho-murG D-glyceraldehyde bifunctional desulfurase]-[disordered- 1-O-(2-acetamido- GDP gatB gatA gatC amidotransferase: SfnG: sfnG CTZ40_RS33785 carbamoyl sulfite cyanate degradation lyase: β pyruvate sulfite RS32005 sulfite uroporphyrinogen-III 4(3H)-one GDP GDP nicotinate-nucleotide guanylyltransferase: synthase: CTZ40_RS26260 cysC O-phospho- N-acetyl-(N-acetyl- -D- 3-phosphate form scaffold 2-deoxy-α-D- ribazoletransferase: cysteine-- gatB gatA gatC dimethyl sulfone phosphate CTZ40_RS04795 UDP C-methyltransferase/ uroporphyrinogen-III bifunctional ribazoletransferase: ribazoletransferase: [corrinoid adenylyltransferase: cofC CTZ40_RS23000 cys [+ 12 isozymes] phosphate ammonium argininosuccinate ornithine (R)-S- glucosaminyl)muramoyl- N 10 -formyl-tetrahydrofolate biosynthesis CTZ40_RS29995 tRNA ligase: a 5-phosphooxy- citrate synthase/ L-serine assimilatory sulfite C-methyltransferase/ protein] complex CTZ40_RS29995 CTZ40_RS29995 adenosyltranferase]- glucopyranosyl)-1D-myo CTZ40_RS27140 enolpyruvoyl- 7,8-didemethyl- (S)-malate PAPS monooxygenase synthase: argG lactoylglutathione L-alanyl-γ-D-glutamyl-L- uroporphyrinogen- [cysteine desulfurase]-S- diaminohydroxyphosphoribosylaminopyrimidine L-glutamyl- acetyltransferase: methylcitrate carbamoyltransferase: CO carbonic anhydrase: uroporphyrinogen- Coα-[α-(5-methylbenzimidazolyl) Coα-[α-(benzimidazolyl) cob(I)inamide -inositol 3-phosphate 2-diphospho- 8-hydroxy-5- adenosylcobalamin CTZ40_RS16270 an L-cysteinyl- ammonium phosphoserine SfnG: sfnG reductase (NADPH) 2 III synthase: deaminase/5-amino-6-(5-phosphoribosylamino) nicotinate adenine Gln CTZ40_RS12165 selenodiglutathione argF lysyl-D-alanyl-D-alanine sulfanylcysteine:[acceptor Cys [tRNA ] CO H synthase: fumarate hydratase: CTZ40_RS23670 a sugar RS31235 a sugar ]-Coβ-adenosylcobamide ]-Coβ-adenosylcobamide 5'-phosphate [tRNA ] 2 2 phosphoadenylyl- phosphatase glutamine NADP-specific : CTZ40_RS08205 CTZ40_RS21400 III synthase: uracil reductase RibD: ribD cob(I)yrinic acid dinucleotide 5'-guanosine deazariboflavin a tetrahydrofolate acetaldehyde protein]-cysteine Cys CTZ40_RS09925 CTZ40_RS14090 methanesulfinate synthetase: glutamate carbonic anhydrase: CTZ40_RS21400 5-amino-6-(5- 5'-phosphate 5'-phosphate a,c-diamide a tRNA sulfate reductase: SerB: serB uroporphyrinogen-III sulfurtransferase: Asp-tRNA(Asn) [+ 3 isozymes] L-citrulline hydrogen sulfide a DNA containing UDP-N-acetyl- 1-myristoyl- a (7Z,10Z,13Z,16Z a (7Z)-3- a (6Z)-3- NAD+ synthase: 2-phospho-L- acetyl phosphate NAD(P)- class II fumarate CTZ40_RS08215 CTZ40_RS29640 dehydrogenase: CTZ40_RS30440 cob(II)alamin- a [glutamine- uroporphyrinogen-III phospho-D- adenosyltransferase: 1-(2-acetamido- /Glu-tRNA(Gln) (R)-lactate methylmalonyl- a lipid II a cis,cis-delta13,31- α adenosylcobinamide a (7Z)-3-oxo- a cis-delta21-3- oxaloacetate C-methyltransferase: CTZ40_RS11720 CTZ40_RS29610 lactate transferase: dependent alcohol hydratase: ser [+ 3 isozymes] CTZ40_RS11685 a malonyl-[acp] an apurinic/ -D-muramoyl- di-trans,octa-cis a palmitoleoyl-[acp] sn-glycerol ,19Z)-3-oxodocosa- a 3-oxohexacosanoyl-[acp] a 3-oxodocosanoyl-[acp] oxohexacos- oxooctadec- a lignoceroyl-[acp] C-methyltransferase: a [cysteine desulfurase]- D-ribulose ribosylamino)uracil CTZ40_RS12430 α ATP [CblC-CblD D-alanyl-D-alanine C50:2-[acp] synthetase]- ATP hexadec-7-enoyl-[acp] dITP oxo-C40:1-[acp] dADP a sugar RS29505 a sugar cobA 2-deoxy- -D- amidotransferase: CTZ40_RS14095 sulfite CoA mutase beta-ketoacyl- apyrimidinic site L-alanyl-γ-D- -undecaprenyl 1-acyl-sn-glycerol-3-phosphate 7,10,13,16,19-pentaenoyl-[acp]3-oxoacyl-[acyl- bifunctional 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- 3-oxoacyl-ACP 3-oxoacyl-[acyl- 7-enoyl-[acp]3-oxoacyl- 6-enoyl-[acp]3-oxoacyl- citrate synthase/ enoyl-ACP cobA 5-phosphate bifunctional CTZ40_RS24940 methionine synthase: acetate kinase: dehydrogenase: citrate glutathioselenol [+ 2 isozymes] sulfur reduction complex] endonuclease L-tyrosine adenylyltransferase/ S-sulfanyl-[disordered- α α Coα-[α-(benzimidazolyl) cob(I)yrinic acid glucopyranosyl)- NAD + adenosylcobalamin gatB gatA gatC NADH repair serine carbamate hydrogencarbonate cob(I)yrinic acid carboxypeptidase/ phosphate adenosylcobinamide RdgB/HAM1 family non- methylcitrate vitamin B12- Co -[ -(5-methylbenzimidazolyl) CTZ40_RS11670 CTZ40_RS07305 II (via polysulfide) ACP synthase II: III: nth glutamyl-L-lysyl- phospho-N- 3-phosphate carrier-protein] carrier-protein] carrier-protein] reductase: carrier-protein] [acyl-carrier- [acyl-carrier- reductase precorrin-2 form scaffold diaminohydroxyphosphoribosylaminopyrimidine β β a,c-diamide 1D-myo-inositol CTZ40_RS12170 assimilatory sulfite methanesulfonate cyanase: cynS a,c-diamide D-alanyl-D-alanine- sulfurtransferase kinase/ canonical purine NTP dependent precorrin-2 bifunctional ]-Co -adenosylcobamide ]-Co -adenosylcobamide gln aconitate hydratase fumarate acetyltransferase: gln CTZ40_RS33630 D-alanyl-D-alanine acetylmuramoyl- acyltransferase: reductase: fabG reductase: fabG reductase: fabG CTZ40_RS28785 reductase: fabG protein] protein] synthase: FabI: fabI a metal a metal protein] complex deaminase/5-amino-6-(5-phosphoribosylamino) dehydro methionine [+ 4 isozymes] reductase (NADPH) endopeptidase: dacB bifunctional DNA- MoeZ: moeZ pyrophosphatase: rdgB ribonucleotide a sugar RS29670 a sugar 3,4-dihydroxy- adenosyltransferase: N-acetyl-1-D-myo- an L-glutaminyl- CTZ40_RS05570 glu phosphate acquisition S 0 adenosyltransferase: pentapeptide- CTZ40_RS06430 adenosylcobinamide- reductase: reductase: CTZ40_RS09925 cation cation cysteine uracil reductase RibD: ribD factor 420-0 synthase: metH NADH acetate AcnA: acnA : CTZ40_RS08205 methanesulfonate pyruvate beta-ketoacyl- formamidopyrimidine 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-[acyl- 3-oxoacyl-ACP enoyl-ACP precorrin-2 C(20)- 2-butanone- cobO inositol-2-amino- an L-glutaminyl- [tRNA Gln ] ethanol fumarate reductase/ CTZ40_RS12430 penicillin-binding bifunctional [glutamine phosphate nucleoside triphosphate fabG fabG bifunctional 2- reductase: RS31860 desulfurase: 5-amino-6-(5- dehydro coenzyme Gln monooxygenase: ACP synthase transferase: [+ 7 isozymes] reductase: reductase: reductase: carrier-protein] reductase: reductase 2-deoxy-alpha- D- [tRNA ] succinate O-acetyl-L-serine CO cyanate glycosylase/ undecaprenyl- 1-myristoyl-2- guanylyltransferase: pyrophosphohydrolase: CTZ40_RS10085 methyltransferase: 4-phosphate cis-aconitate hydrogen sulfide hydrogen selenide a phosphate 2 cob(I)yrinic acid protein 2: mrdA synthetase] methylcitrate acetate acetate CTZ40_RS11720 phospho-D- adenosylcobinamide F -0 reductase: Gln CTZ40_RS06835 a N-acetylglucosamine--N- II: fabF diphospho-CTZ40_RS30470N- palmitoleoyl- a (3R,7Z,10Z,13CTZ40_RS28785Z,16Z CTZ40_RS28785 CTZ40_RS28785 reductase: fabG CTZ40_RS28785 3-oxoacyl-ACP 3-oxoacyl-ACP FabI: fabI glucopyranoside 420 a tRNA dehydrogenase DNA-(apurinic CTZ40_RS30025 CTZ40_RS24475 CTZ40_RS20365 synthase/GTP ribitylamino)uracil monoester a,c-diamide a cis,cis-delta15,33- acyl-carrier protein adenylyltransferase/ a (3R)-3- a (3R)-3- a (3R,7Z)-3-hydroxy- a cis-delta21-3- synthase/citrate ribonucleoside- a trans-tetracos- a sugar RS08390 a sugar sirohydrochlorin [+ 2 isozymes] CTZ40_RS24935 flavoprotein: acid phosphatase: a polysulfide D-ala acetylmuramyl-(tetrapeptide) acyl-carrier protein or apyrimidinic acetylmuramoyl- sn-glycerol ,19Z)-3-hydroxydocosa- reductase: reductase: an S-sulfanyl-[cysteine cyclohydrolase II: deacetylase: mshB aconitate hydratase glyphosate sulfite adenosyltransferase: 3-oxo-C52:2-[acp] UMP [glutamine synthetase]- adenosyl-cobinamide hydroxyhexacosanoyl-[acp] hydroxydocosanoyl-[acp] hexadec-7-enoyl-[acp] dIMP hydroxyC40:1-[acp] synthase: diphosphate 2-enoyl-[acp] precorrin-3A bifunctional oxidized CTZ40_RS13955 taurine degradation IV CTZ40_RS27365 pyrophosphoryl-undecaprenol site) lyase: mutM L-alanyl-γ-D- 3-phosphate 7,10,13,16,19-pentaenoyl-[acp] a (3R,7Z)-3-CTZ40_RS28785 a (3R,6Z)-3-CTZ40_RS28785 desulfurase]-S- CTZ40_RS34485 superpathway of coenzyme A biosynthesis I (bacteria) superpathway of thiamine diphosphate biosynthesis II Amine and Polyamine Biosynthesis AcnA: acnA cysteine synthase: degradation II polysulfide a [cobalamin cobO adenosylcobalamin- adenylyl-L-tyrosine phosphate CTZ40_RS02330 reductase: adenosylcobinamide GlcN-Ins factor 420-0 (R)-NADHX CTZ40_RS13960 a [cyanocobalamin a 5'-phospho- a 3'-terminal glutamyl-L-lysyl- sulfanyl-[disordered- 1-deoxy-L- serine glycine cleavage system CTZ40_RS25630 bifunctional reductase: trafficking triphosphate [methylmalonyl- phosphorylase: hydroxyhexacos- hydroxyoctadec- (2S,3S)-2- CTZ40_RS13265 precorrin- kinase/ bifunctional reductase CblC] [DNA] unsaturated sugar D-alanyl-D-alanine a sugar RS33565 a sugar form scaffold glycero-tetrulose 3-methyl-2- a 5,10- hydroxymethyltransferase:protein GcvH: gcvH glutamate-- D-threo-isocitrate fumarate reductase/ glyphosate taurine RNase H/acid CTZ40_RS36695 protein CblD] CoA mutase] a [glutamineCTZ40_RS29645 7-enoyl-[acp] 6-enoyl-[acp] methylcitrate CTZ40_RS13270 cobalt- 3B ARP adenosylcobinamide- L-cysteine : 1 D- cys a 7,8-dihydrofolate a 5-methyltetrahydrofolate glu ectoine biosynthesis ADP-dependent protein] complex 4-phosphate oxobutanoate methylenetetrahydrofolate CTZ40_RS12510 glycine cleavage system tRNA ligase: putrescine succinate glycine taurine phosphatase: synthetase]-O synthase: [cysteine desulfurase]-S- phosphate myo-inositol 2- a ThiS sulfur- NAD(P)H-hydrate cys ADP sirohydrochlorin biosynthesis I NADP-dependent oxidase dioxygenase: CTZ40_RS28810 a polysulfide 4 -(5'-adenylyl) cobG 3-methyl-2-oxobutanoate guanylyltransferase: amino-2-deoxy-α- an oxidized [+ 2 isozymes] protein GcvH: gcvH CTZ40_RS11370 an L-glutamyl- dehydrogenase sulfanylcysteine:[acceptor 6,7-dimethyl-8- cysteine carrier protein dehydratase/ isocitrate ThiO: thiO CTZ40_RS04270 phosphate CTZ40_RS30025 D-glucopyranoside [tRNA Glu ] asp flavoprotein: (aminomethyl) -L-tyrosine a sugar RS34725 a sugar protein]-cysteine hydroxymethyltransferase: desulfurase: factor 420 NAD(P)H-hydrate dehydrogenase: glyoxylate 2-aminoacetaldehyde precorrin-3B ribityllumazine glu CTZ40_RS30685 sulfurtransferase: panB ligase: CTZ40_RS11720 a tRNA aspartate kinase: arg epimerase: phosphonate synthase: adenosyl-cobinamide CTZ40_RS33635 CTZ40_RS30690 17 asp CTZ40_RS33095 CTZ40_RS18065 a peptidoglycan a [disulfide- 1-palmitoyl- 6-methoxy-2-all- salicin 6- a (5Z)-3- dCDP cobalt-factor III precorrin-3B (C )- a [cysteine CTZ40_RS11720 CTZ40_RS34490 phosphate [+ 2 isozymes] CTZ40_RS22460 NADP-dependent cob(II)alamin- an apo-["base- a cis,cis-delta11,29- a protein with a (7Z)-hexadec- an (11Z)-3-oxo- a cis-delta19-3- acetoacetyl-CoA (R)-lactate a pimeloyl-[acp] 2-dehydropantoate an [L-cysteine a carboxy- (S)-NADHX a cis-delta19-C38:1-[acp] a malonyl-[acp] a malonyl-[acp] dimer with bond carrier a palmitoleoyl-[acp] sn-glycerol a malonyl-[acp] trans-octaprenyl- phosphate a 3-oxotetracosanoyl-[acp] a 3-oxodocosanoyl-[acp] oxododec- methyltransferase: desulfurase]-(S- L-aspartyl- isocitrate succinate ATP [CblC-CblD off/His-on" C48:2-[acp] reduced L- 7-enoyl-[acp] icos-11-enoyl-[acp] XTP oxo-C38:1-[acp] vitamin B12- methyl ester a sugar RS37680 a sugar aspartate 1- superpathway of tetrahydrofolate biosynthesis bifunctional deacetylmycothiol desulfurase]-S- adenylated-[ThiS a reduced Carbohydrate Degradation pentapeptide protein] carrying 3-phosphate 1,4-benzoquinone 6-phospho-beta- 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- 3-hydroxybutyryl- 5-enoyl-[acp]3-oxoacyl-ACP D-2-hydroxyacid enoyl-ACP CTZ40_RS20365 sulfanyl) -[disordered- 2-dehydropantoate 4-phosphate agmatine ATP-dependent complex] B12-enzyme] beta-ketoacyl- beta-ketoacyl- cysteine residues 1-acyl-sn-glycerol- beta- demethylmenaquinone 3-oxoacyl-[acyl- 3-oxoacyl-ACP dependent 2 6,7-dimethyl-8-(1- dehydrogenase: DSBA glucosidase: RdgB/HAM1 family non- dehydrogenase: decarboxylase: adenosylcobinamide sulfanyl-L-cysteine sulfur-carrier protein] D-glyceraldehyde factor 420 isoleucine-- Secondary Metabolite Degradation cob(I)yrinic acid ACP synthase II: ACP synthase II: stems (meso- a disulfide bond 3-phosphate methyltransferase: carrier-protein] carrier-protein] reductase: carrier-protein] CoA reductase: reductase form scaffold D-ribityl)lumazine 2-reductase: mycothiol bifunctional ile NADH-hydrate CTZ40_RS15305 oxidoreductase: ketoacyl- canonical purine NTP ribonucleotide precorrin-4 CTZ40_RS22220 kinase/ 3-phosphate a (6S)-5-formyltetrahydrofolate aspartate- agmatinase: a,c-diamide CTZ40_RS33630 CTZ40_RS33630 diaminopimelateN-acetylmuramoyl- acyltransferase: CTZ40_RS07665 CTZ40_RS26665 reductase: fabG reductase: fabG CTZ40_RS28785 reductase: fabG dehydrogenase: CTZ40_RS28785 CTZ40_RS25985 FabI: fabI protein] complex CTZ40_RS26380 synthase: methylenetetrahydrofolate tRNA ligase: dehydratase: Macromolecule Modification superpathway of glucose and xylose degradation chitin degradation III (Serratia) CTZ40_RS12115 ACP pyrophosphatase: rdgB reductase: riboflavin synthase: GTP adenosylcobinamide- cysteine semialdehyde speB glycogen degradation II adenosyltransferase: containing)L-alanine amidase: 6-phospho-beta- CTZ40_RS02325 a sugar RS12090 a sugar cobalt-precorrin-3 mshD deoxyxylulose- gly dehydrogenase/ CTZ40_RS30530 an L-isoleucyl- CTZ40_RS22460 2-oxoglutarate anhydromuropeptides recycling I beta-ketoacyl- beta-ketoacyl- CTZ40_RS06430 synthase demethylmenaquinone 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-[acyl- 3-oxoacyl-ACP 3-oxoacyl- D-isomer specific CTZ40_RS10085 enoyl-ACP precorrin-4 C(11)- CTZ40_RS34475 β-alanine phosphate desulfurase: methylenetetrahydrofolate 5-formyltetrahydrofolate dehydrogenase: D-galactonate degradation CTZ40_RS12430 CTZ40_RS11710a peptidoglycan DSBA nucleoside triphosphate (R)-pantoate Ile agmatinase: D-glucopyranose glucosidase: 3-hydroxybutyryl- 2-hydroxyacid methyltransferase: 5-phosphate reductase [NAD(P)H]: metF methenyltetrahydrofolate cyclo-ligase: [tRNA ] tRNA processing ACP synthase ACP synthase L-alanyl-γ-D- dimer with [+ 71-palmitoyl-2- isozymes] II: fabF methyltransferase: reductase: reductase: carrier-protein] reductase: [acyl-carrier- reductase guanylyltransferase: mycothiol CTZ40_RS11720 Ile CTZ40_RS18060 speB GlcNAc-1,6- 6-phosphate chitin cob(I)yrinic acid [+ 5 isozymes] oxidoreductase: CTZ40_RS27385 pyrophosphohydrolase: CoA ribonucleoside- cobM GTP synthase: glycine cyclohydrolase: CTZ40_RS23955 a tRNA NADH a glycogen II: fabF II: fabF a [disulfide-bond beta-ketoacyl- CTZ40_RS21810 CTZ40_RS28785 CTZ40_RS28785 reductase: fabG CTZ40_RS28785 protein] dehydrogenase FabI: fabI riboflavin CTZ40_RS30025 [+ 2 isozymes] [+ 2 isozymes] anhMurNAc- D-galactonate glutamyl-meso-2,6- pentapeptide CTZ40_RS33955 acyl-carrier protein palmitoleoyl- 3-methyl-6-methoxy- β-D-glucose CTZ40_RS24475 diphosphate a [cysteine desulfurase]- cyclohydrolase CTZ40_RS23175 oxidase CTZ40_RS15315 glucose-6- a,c-diamide a cis-delta21-3- a cis,cis-delta13,31- ACP synthase II: salicyl alcohol a (3R)-3- a (3R)-3- a (3R,11Z)-3-hydroxy- a cis-delta19-3- dehydrogenase: reductase: NAD-binding an enoylpimeloyl- a sugar RS13215 a sugar pantoate--beta- putrescine a polycistronic L-Ala-γ-D-Glu- galactonate glycogen acyl-carrier protein acyl-carrier protein diaminopimeloyl- stem (meso- a protein with carrier protein] sn-glycerol 2-octaprenyl-1,4- 6-phosphate reductase: precorrin-5 [scaffold protein- I FolE: folE adenosylcobinamide- a 5,10-methylenetetrahydrofolate a 5,10-methenyltetrahydrofolate L-aspartate 4- phosphate adenosyltransferase: oxo-C40:1-[acp] 3-oxo-C50:2-[acp] hydroxytetracosanoyl-[acp] hydroxydocosanoyl-[acp] icos-11-enoyl-[acp] XMP hydroxyC38:1-[acp] CTZ40_RS33520 protein: [acp] methyl ester bifunctional alanine ligase: [+ 2 isozymes] ThiO: thiO tRNA precursor D-alanyl-D-alanine diaminopimelate a disulfide bond with reduced L- 3-phosphate CTZ40_RS33630a (9Z)-3-oxo- benzoquinone (S)-3- a (3R,5Z)-3-fabG CTZ40_RS13265 cobalt-precorrin-4 (2Fe-2S)] complex 7,8- GDP semialdehyde DAP-D-Ala dehydratase: phosphorylase: a [cobalamin cobO a holo-["base- CTZ40_RS04740 riboflavin kinase/ CTZ40_RS17100 a thiocarboxy- 1-deoxy-D-xylulose dehydrogenase: a [cyanocobalamin containing) cysteine residues acyl-carrier protein hydroxybutanoyl- hydroxydodec- dihydroneopterin AIR 2-iminoacetate bifunctional dgoD CTZ40_RS12015 chitin [(1->4)-β-N-acetyl-D-glucosaminyl] trafficking triphosphate off/His-on" octadec-9- CTZ40_RS13270 [ThiS-Protein] CTZ40_RS31355 n pyruvate FAD synthetase: 5-phosphate leucine-- diaminobutyrate- N-acetylmuramoyl- 2-dehydro-3-deoxy- reductase CblC] enoyl-[acp] CoA 5-enoyl-[acp] a sugar RS00640 a sugar 3'-triphosphate methylenetetrahydrofolate leu 6-phospho α -(1->4)-2-(acetylamino)-2- protein CblD] B12-enzyme] CDP CTZ40_RS10595 adenosylcobalamin phosphomethylpyrimidine tRNA ligase: -2-oxoglutarate L-alanine amidase: D-galactonate an -limit dextrin (R)-pantothenate dehydrogenase/ spermidine biosynthesis I D-glucono- deoxy-D-glucono-1,5-lactone a [co-chaperone]- salvage from cobalamin synthase ThiC: thiC thiazole synthase: CTZ40_RS27205 an L-leucyl- transaminase: ectB CTZ40_RS11710 chitinase: cobalt- precorrin-6A FMN pyridoxal 5'-phosphate biosynthesis I methenyltetrahydrofolate a tRNA precursor a tRNA precursor with 1,5-lactone 4-alpha- [scaffold protein- Leu CTZ40_RS11635 a 3-methyl- type III CTZ40_RS30345 [tRNA ] L-2,4- [+ 5 isozymes] UDP-N-acetyl-α-D-muramoyl- ditrans,octacis- 1-stearoyl- arbutin-6- a [DNA]-3'- a 5'-phospho- (2Z,4E)-2- (3R,5S)-3- UDP precorrin-5A 7,8- cob(I)alamin cyclohydrolase: with a 5' extension a 5' extension and glucanotransferase: D-alanyl-D-alanine a cis,cis-delta9,27- a (4Z)-hexadec- a holo [D-alanyl a 3-oxoglutaryl- a (3R,5Z)-3-hydroxy- a cis,cis-delta21,39- a cis-delta17-3- a (5Z)-dodec- a sugar RS25235 a sugar (2Fe-2S)] complex HMP-P a tRNA Leu 6-phosphogluconolactonase: [+ 8 isozymes] L-alanyl-γ-D-glutamyl-L-lysine a cis-delta17-C36:1-[acp] a malonyl-[acp] a malonyl-[acp] undecaprenyldiphospho- branched 2,3,4- a palmitoyl-[acp] sn-glycerol a malonyl-[acp] D-ala ala hydroxyhexa- hydroxy-1- bifunctional pantothenate D-erythrose CTZ40_RS15315 diaminobutanoate SAM and a long 3' trailer a short 3' extension 2-dehydro-3-deoxy- malQ β C46:2-[acp] 4-enoyl-[acp] phosphate hydroxyl [DNA] [acp] methyl ester tetradec-5-enoyl-[acp] 3-hydroxyC58:2-[acp] oxo-C36:1-[acp] 5-enoyl-[acp] dihydroneopterin 2-[(2R,5Z)-2-carboxy- tetrapyrrole biosynthesis β γ pgl [(1->4)- -N-acetyl-D- N-acetyl-(N-acetyl-β-D- saturated fatty acid 3-phosphate carrier protein] 6-phospho-beta- ATP-dependent 2,4-dienedioate pyrroline-5- vitamin B12- riboflavin kinase/ kinase: chorismate 4-phosphate ribonuclease N-acetyl- -D- L-alanyl- -D- UDP-N-acetylmuramoyl- beta-ketoacyl- beta-ketoacyl- fatty acid-- 1-acyl-sn-glycerol- beta-ketoacyl- cysteine--1-D-myo- 3-oxoacyl-[acyl- 3-oxoacyl-ACP 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- enoyl-ACP 3'-phosphate bifunctional 4-methylthiazol-5(2H)- I (from glutamate) diaminobutyrate ribonuclease D: D-galactonate a debranched glucosaminyl] -(1->4)-N-acetyl- D-aspartate pyridoxal phosphate- 4-oxalocrotonate dependent a 10-formyltetrahydrofolate glucosamine-1,6- glutamyl-meso-2,6- D-gluconate a chitodextrin n tripeptide--D-alanyl- ACP synthase II: glucosaminyl)muramoyl- 3-phosphate ACP synthase II: glucosidase: DNA ligase: carrier-protein] reductase: carrier-protein] carrier-protein] carboxylatepyrroline-5- reductase FAD synthetase: CTZ40_RS17085 hydroxymethylpyrimidine CTZ40_RS08665ribonuclease PH: P protein 6-phosphate α-limit dextrin ACP synthase II: CoA ligase inosityl 2-amino- dependent tautomerase ribonucleotide aminodeoxychorismate/ cob(II)alamin ylidene]ethyl phosphate acetyltransferase: anhydro-N-acetyl- diaminopimeloyl- 2-deoxy-2-amino-D-gluconate D- alanine ligase: L-alanyl-γ-D-glutamyl-L- CTZ40_RS26665 CTZ40_RS04240 carboxylate a sugar RS25425 a sugar cobalt- precorrin-6B a [chaperone-ATP]- CTZ40_RS10595 type I pantothenate ribonuclease D: CTZ40_RS25655 component: 6-phosphate CTZ40_RS33630 CTZ40_RS33630 family protein: acyltransferase: CTZ40_RS33630 2-deoxy-alpha-D- reductase: fabG CTZ40_RS28785 reductase: fabG reductase: fabG aminotransferase: family protein: FabI: fabI anthranilate synthase kinase/ glu ectA putrescine dAdoMet β-D-muramate D-alanine lysyl-D-alanyl-D-alanine D-aspartate ligase: reductase: reductase: precorrin-5B [co-chaperone]- CTZ40_RS08665 rnpA decarboxylating 6- maltodextrin chitinase: exo-chitinase exo-chitinase (non- CTZ40_RS30465 beta-ketoacyl- beta-ketoacyl- ditrans,octacis- CTZ40_RS22880 CTZ40_RS06430 beta- glucopyranoside 6-phospho-beta- ATP-dependent 3-oxoacyl-ACP 3-oxoacyl-[acyl- 3-oxoacyl-ACP 3-oxoacyl-ACP CTZ40_RS14390 CTZ40_RS35930 enoyl-ACP precorrin-6y C5,15- kinase: component II: cob(I)yrinic acid phosphomethylpyrimidine glutamate-- 4-phospho- CTZ40_RS21935 CTZ40_RS10085 [scaffold protein- FAD 7,8- val (2S)-4-acetamido- beta-N- D-glyceraldehyde phosphogluconate (reducing end): UDP-N-acetylmuramoyl- ACP synthase ACP synthase [+ 11 isozymes] [+ 7 isozymes] ketoacyl- ligase: glucosidase: DNA ligase: reductase: carrier-protein] reductase: reductase: proC reductase cobalt-precorrin- CTZ40_RS22445 CTZ40_RS09640 a,c-diamide kinase: thiD tRNA ligase: D-erythronate valine--tRNA ligase: spermidine a tRNA precursor with pyruvate phosphorylase: CTZ40_RS11635 reducing end): undecaprenyldiphospho-N- a 3-methyl- 1-stearoyl- pyridoxal phosphate- 4-oxalocrotonate methyltransferase (2Fe-2S)] complex 2-(2-carboxy-4- 2-aminobutanoate acetylhexosaminidase: 3-phosphate CTZ40_RS27385 CTZ40_RS37690 hypothetical ribonucleoside- 5B (C(1))- dihydroneopterin CTZ40_RS26990 an L-valyl- synthase: a short 3' extension dehydrogenase: gnd CTZ40_RS12015 [+ 8 isozymes] CTZ40_RS12450 CTZ40_RS12450 tripeptide--D-alanyl- II: fabF II: fabF acetyl-(N-acetylglucosaminyl) branched 2-palmitoyl- ACP a D-alanyl-CTZ40_RS33095 CTZ40_RS28785 reductase: fabG CTZ40_RS28785 CTZ40_RS28785 FabI: fabI a sugar RS26100 a sugar (decarboxylating) (R)-4'- aminodeoxychorismate/ adenosyltransferase: methylthiazol-5- CTZ40_RS11370 CTZ40_RS25435 D-glucopyranose diphosphate AMP acyl-carrier protein β-D-glucose dependent tautomerase diphosphate HMP-PP an L-glutamyl- Val ectoine synthase: a tRNA precursor L-alanyl-γ-D- D- alanine ligase: a cis-delta19-3- a cis,cis-delta11,29- γ synthase [DNA] a (3R)-3-hydroxyglutaryl- a (5Z)-3-oxo- a cis,cis-delta21,39- a cis-delta17-3- protein: a (3E,5Z)-dodeca- predicted methyltransferase: phosphopantothenate dihydroneopterin CTZ40_RS12430 [tRNA ] CTZ40_RS12810 D-ribulose acyl-carrier protein acyl-carrier protein muramoyl-L-alanyl- -D- 2,3,4-saturated sn-glycerol [D-alanyl hydroquinone aminotransferase: family protein: subunit CbiE: cbiE anthranilate synthase yl)ethyl phosphate [tRNA Glu ] with a 5' extension α-D- oxo-C38:1-[acp] 3-oxo-C48:2-[acp] 6-phosphate [acp] methyl ester tetradec-5-enoyl-[acp] 3-oxo-C58:2-[acp] hydroxyC36:1-[acp] CTZ40_RS17520 reductase: 3,5-dienoyl-[acp] Val CTZ40_RS31645 [+ 2 isozymes] beta-N- glutamyl-meso- 5-phosphate CTZ40_RS39925 glutamyl-N-(β-D-asparatyl) fatty acyl-CoA 3-phosphate II: fabF carrier protein] ABC CTZ40_RS20335 bifunctional aldolase: folB component II: cob(I)yrinic acid a tRNA myo-, chiro- and scyllo-inositol degradation N,N'-diacetylchitobiose UDP-N-acetyl-α-D-muramoyl-L-alanyl- a (6Z)-3- CTZ40_RS35905 CTZ40_RS07850 CTZ40_RS13265 ectoine ectoine (3R)-3-hydroxy-2-oxo- acetylhexosaminidase: diaminopimelate glucopyranose ROK family -L-lysyl-D-alanyl-D-alanine (3E)-2-oxohex- Hyp transporter cobalt- precorrin-7 phosphopantothenoylcysteine glutamyl-tRNA ribonuclease PH: ribonuclease D: γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine acyl-carrier protein oxooctadec- pyruvate CTZ40_RS13270 a [chaperone- 6-(hydroxymethyl) CTZ40_RS19755 a,c-diamide thiamine 4 phosphooxybutanoate ectoine spermidine CTZ40_RS07650 1-phosphate 3-enedioate a sugar RS26675 a sugar an [2Fe-2S] NAD de novo biosynthesis reductase: ribonuclease ribulose- ribose-5-phosphate glucokinase: beta-N- Chlorinated 6-enoyl-[acp] of ectoine precorrin-6A ADP]-[disordered- decarboxylase/ -7,8-dihydropterin 4-amino-4- adenosyltransferase: phosphate CTZ40_RS25655 CTZ40_RS08665 dUDP precorrin-6y C5,15- cluster protein I (from aspartate) CTZ40_RS21390 3-phosphoserine/ 1,6-anhydro-N- 1D-chiro-inositol phosphate 3- isomerase: CTZ40_RS07585 acetylhexosaminidase: cobalt-precorrin- form scaffold phosphopantothenate-- cobO synthase: P protein Compound Degradation methyltransferase 2-amino-4-hydroxy-6- deoxychorismate phosphohydroxythreonine acetyl-β-muramate epimerase: CTZ40_RS26900 phosphomannomutase/ ROK family CTZ40_RS25435 6A reductase: protein] complex cysteine ligase CoaBC: coaBC cob(II)alamin- CTZ40_RS30370 (S)-4-amino-5- alanine- component: D-xylose (decarboxylating) hydroxymethyldihydropteridine aminodeoxychorismate transaminase: serC phosphoglucomutase: glucokinase: beta-N- pentachlorophenol β 1-stearoyl- predicted CTZ40_RS20340 asp (R)-4'- [corrinoid oxopentanoate -tRNA rnpA rpe a [2-oxoglutarate dehydrogenase E2 an N-acetyl- - a [2-oxoglutarate a [lipoyl-carrier subunit CbiE: cbiE diphosphokinase: folK a cis,cis-delta17,29- uroporphyrinogen-III a (7Z)-hexacos- acibenzolar-S-methyl methylsalicylate a cis,cis-delta19,37-3- a cis,cis-delta17,35- a cis-delta15-3- 6 acryloyl-CoA a glutaryl-[acp] lyase: CTZ40_RS33945 Aromatic Compound Biosynthesis myo-inositol D-ribose 5- CTZ40_RS24985 CTZ40_RS30245 acetylhexosaminidase: degradation 6 a cis-delta15-C34:1-[acp] a malonyl-[acp] a malonyl-[acp] a stearoyl-[acp] sn-glycerol a malonyl-[acp] H O diphosphate leukotriene-D4 3'-AMP ABC L-aspartate phosphopantothenoyl- D-glyceraldehyde phosphoserine molybdenum cofactor biosynthesis ligase: xylose protein] N -dihydrolipoyl-L-lysine D-hexosaminide 2 dehydrogenase protein]-N -[(R) cobalt- (7,8-dihydropterin- adenosyltranferase] glutamate-1- pyruvate C48:2-[acp] 7-enoyl-[acp] hydroxy-C56:2-[acp] 3-hydroxyC54:2-[acp] oxo-C34:1-[acp] methyl ester a sugar a sugar thiamine phosphate transaminase: isomerase: D-xylulose phosphate CTZ40_RS07650 multifunctional oxoglutarate beta-ketoacyl- beta-ketoacyl- uroporphyrinogen-III C- beta-N- 3-phosphate beta-ketoacyl- inorganic carboxylesterase/ carboxylesterase/ membrane 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- multifunctional 2',3'- E2 protein] N 6 -dihydrolipoyl]- crotonyl-CoA enoyl-ACP transporter precorrin-6B precorrin-8x oxidase: L-cysteine 6-yl)methyl semialdehyde- 3-phosphate alaS N-acetyl-D- scyllo-inositol 1-keto-D-chiro-inositol 1-acyl-sn-glycerol- an [Fe-S cluster 4-aminobenzoate serC chorismate biosynthesis I xylA 5-phosphate pentachlorophenol decarboxylase/oxoglutarate ACP synthase II: ACP synthase II: methyltransferase: cobA acetylhexosaminidase: ACP synthase II: diphosphatase: lipase family protein: lipase family protein: dipeptidase: carrier-protein] carrier-protein] carrier-protein] cyclic-nucleotide 2'- -dihydrolipoyl- L-lysine dihydrolipoyl carboxylase/ reductase of a sugar CTZ40_RS17095 bifunctional diphosphate 2,1- deoxyxylulose- alanine- 2,3-dihydroxybenzoate muramate 6- inositol 2- 3-phosphate precorrin-8X biosynthesis thiamine- N-acetyl-D-glucosamine pentachlorophenol CTZ40_RS25435 CTZ40_RS11955 CTZ40_RS11955 CTZ40_RS24825 L-lysine dihydrolipoyl reductase: 2-iminosuccinate phosphopantothenoylcysteine aminomutase: 4-phosphooxy- cys GTP -tRNA biosynthesis phosphate dehydrogenase: dehydrogenase thiamine CTZ40_RS33630 CTZ40_RS33630 bifunctional acyltransferase: CTZ40_RS33630 CTZ40_RS17270 reductase: fabG reductase: fabG reductase: fabG phosphodiesterase/ dehydrogenase: FabI: fabI cob(I)alamin- phosphate kinase: 5-phosphate ala an uncharged tRNA D-xylulose monooxygenase: beta-N- dehydrogenase: ccrA predicted methylmutase: chaperone]-ATP decarboxylase/ dihydropteroate hemL L-threonine ligase: D-erythrose glycolysis III (from glucose) Glycolysis N-acetylmuramic CTZ40_RS26375 transketolase: (1,4)-β-D-xylan chitin degradation II (Vibrio) pyrophosphate-binding beta-ketoacyl- beta-ketoacyl- uroporphyrinogen-III CTZ40_RS06430 sodium-translocating carboxylesterase/ carboxylesterase/ membrane 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP 5'-nucleotidase/ lpdA enoyl-ACP quinolinate [corrinoid CTZ40_RS11220 synthase: ATP CTZ40_RS14885 beta- lpdA CTZ40_RS20370 cysteine 4-phosphate acid 6- CTZ40_RS05505 degradation 2,3,5,6-tetrachloro- subunit/dihydrolipoyllysine- C-methyltransferase/ acetylhexosaminidase: pyrophosphatase: lipase family protein: lipase family protein: dipeptidase: 3'-nucleotidase: crotonyl-CoA ABC cobalt-precorrin-7 phosphopantothenate-- synthase: folP adenosyltranferase] CTZ40_RS23175 GTP 3',8- alaS an L-alanyl- 3-deoxy-7- chorismate xylulokinase: ACP synthase ACP synthase [+ 71-stearoyl-2- isozymes] ketoacyl- reductase: reductase: reductase: dihydrolipoyl reductasea sugar a sugar synthase 5-aminolevulinate desulfurase: [+ 2 isozymes] chitin 1,4-benzoquinone residue succinyltransferase uroporphyrinogen-III CTZ40_RS07650 CTZ40_RS37930 CTZ40_RS37930 CTZ40_RS00370 CTZ40_RS30965 dihydrolipoyl transporter cysteine ligase CoaBC: coaBC thiamine diphosphate [tRNA Ala ] phosphoheptulonate isochorismate D-glucopyranose phosphate D-glucarate xylB II: fabF II: fabF ACP CTZ40_RS17620 CTZ40_RS28785 CTZ40_RS28785 CTZ40_RS28785 dehydrogenase: carboxylase/ FabI: fabI hydrogenobyrinate NadA: nadA lipoate biosynthesis cob(I)yrinic acid [+ 2 isozymes] cyclase scyllo-inosose β an N-acetyl-β- stearoyl-sn dehydrogenase: of a sugar CTZ40_RS11720 Ala etherase: murQ a (1->4)- -D-xylan subunit: CTZ40_RS12825 a cis-delta17-3- a cis,cis-delta19,31- synthase: CTZ40_RS21400 acyl-carrier protein + a cis,cis-delta19,37- a cis,cis-delta17,35- a cis-delta15-3- a [2-oxoglutarate a [lipoyl-carrier reductase: an enoylglutaryl- bifunctional cobalt- 7,8- a,c-diamide MoaA: moaA a tRNA synthase: aroF synthase degradation II D-xylulose D-glucopyranose D-mannose acyl-carrier protein acyl-carrier protein an alcohol -glycerol 3- synthase phosphate H MeOH acibenzolar MeOH salicylate leukotriene-E4 gly lpdA and incorporation 1-deoxy-D- 3-amino-1- ROK family D-sedoheptulose D-glyceraldehyde endo-1,4-beta- chitinase: a [2-oxoglutarate dehydrogenase E2 D-hexosamine adenosine lpdA 6 precorrin-7 (C(5))- hydrogenobyrinate quinolinate 4'-phosphopantetheine dihydropteroate porphobilinogen [+ 2 isozymes] (8S)-3',8-cyclo-7,8- DhbC: dhbC lipoprotein posttranslational modification N-acetyl-D- 6-phosphate degradation oxo-C36:1-[acp] 3-oxo-C50:2-[acp] precorrin-2 II: fabF 3-oxo-C56:2-[acp] 3-oxo-C54:2-[acp] hydroxyC34:1-[acp] dehydrogenase protein]-N - ccrA [acp] methyl ester adenosyltransferase: xylulose 5- hydroxyacetone 3-deoxy-[+ 2 isozymes] 5-phosphate CTZ40_RS11635 6 phosphate a (9Z)-3- III (Bacillus) synthase: hemB an [L-cysteine a carboxy-adenylated glucokinase: 7-phosphate 3-phosphate xylanase: protein] N -S-succinyldihydrolipoyl-L-lysine 6 lipoyl-L-lysine (R)-methylmalonyl- predicted methyltransferase/ a,c-diamide synthase: bifunctional CTZ40_RS12430 dihydroguanosine isochorismate glucosamine D-glucarate E2 protein] N pantetheine- phosphate 1-phosphate desulfurase]-S- [small subunit of D-arabino- CTZ40_RS07585 CTZ40_RS07505 [+ 8 isozymes] D-mannopyranose 2,3,5,6- acyl-carrier protein oxooctacos- CoA ABC cobalt-precorrin- CTZ40_RS31690 carboxylating folylpolyglutamate 5'-triphosphate a [prolipoprotein]- 6-phosphate glucarate a (1->4)-β-D-xylan -lipoyl-L-lysine a sugar a sugar phosphate an octanoyl-[acp] cob(I)yrinic acid porphobilinogen sulfanyl-L-cysteine molybdopterin synthase] heptulosonate ROK family 3D-(3,5/4)- 6-phosphate tetrachlorohydroquinone 9-enoyl-[acp] transporter 6B (C(15))- nicotinate- thiamine salvage II cyclic pyranopterin isochorismatase: L-cysteine N-acetylglucosamine- dehydratase: oligosaccharide a chitodextrin mannose-6- hydrogenobyrinate adenylyltransferase: synthase/ lipoyl(octanoyl) a,c-diamide 7-phosphate transaldolase: tal of a sugar nucleotide monophosphate asn CTZ40_RS09355 glucokinase: 6-phosphate trihydroxycyclohexane-1,2-dione CTZ40_RS27370 phosphate methyltransferase: a,c-diamide coaD dihydrofolate transferase adenosyltransferase: hydroxymethylbilane 3-dehydroquinate prolipoprotein 5-dehydro-4- xylan 1,4-beta- diphosphorylase: 4-amino-2-methyl-5- synthase (2S,3S)-2,3- CTZ40_RS30245 deacetylase: nagA 3D-(3,5/4)- D-erythrose isomerase: a nascent peptidoglycan D-cellobiose a negatively CTZ40_RS20320 putative synthase: a [glycine-cleavageLipB: lipB synthase: hemC diacylglyceryl deoxy-D-glucarate F6P xylosidase: a cis,cis-delta15,27- a (5Z)-tetracos- a cis,cis-delta15,33-3- a cis,cis-delta19,31- a cis-delta13-3- CTZ40_RS17090 3'-dephospho- cobO pyridoxine an L-asparaginyl- synthase: aroB dihydroxy-2,3- trihydroxycyclohexane- 4-phosphate CTZ40_RS38210 (meso-DAP containing) a cis-delta13-C32:1-[acp] a malonyl-[acp] a malonyl-[acp] methyl (indol-3-yl)acetate a malonyl-[acp] all-trans-retinyl palmitate a uracil in DNA DMK-12 4-hydroxybenzoate 3'-GMP (R)-NADPHX crotonyl-CoA an octanoyl-[acp] predicted CTZ40_RS27005 complex H protein] pyrimidinemethanol [+ 2 isozymes] MoaC: moaC transferase: D-glucopyranose D-glucosamine CTZ40_RS32575 2,3,5-trichloro- 2,3-dihydroxybenzoate ATP 6'-phosphate supercoiled DNA cobaltochelatase: CoA adenosylcob(III) 5'-phosphate a thiocarboxylated [tRNA Asn ] 3-dehydroquinate 5-dehydro-4- lytic transglycosylase C46:2-[acp] 6-phospho-beta- 5-enoyl-[acp] hydroxy C52:2-[acp] 3-hydroxyC50:2-[acp] oxo-C32:1-[acp] ABC cobalt-precorrin-8 N 6 -octanoyl-L-lysine dihydrobenzoate 6-phosphate 6-phosphate 1,2-dione acylhydrolase 6-(glutathion-S- beta-ketoacyl- beta-ketoacyl- carboxylesterase/ beta-ketoacyl- carboxylesterase/ uracil-DNA demethylmenaquinone 4-hydroxybenzoate 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- multifunctional 2',3'- DNA bifunctional crotonyl-CoA enoyl-ACP CTZ40_RS31700 NaMN 7,8-dihydrofolate alamin-[corrinoid bifunctional cyclic pyranopterin Asn CTZ40_RS30785 transketolase: β a chitodextrin mannose-6- a sugar a sugar dephospho- preuroporphyrinogen [small subunit of tRNA synthase: 2,3-dihydro-2,3- (decyclizing): iolD deoxyglucarate -D-xylopyranose domain-containing (2,3-dihydroxybenzoyl) glucosidase: lipase family protein: lipase family protein: glycosylase: methyltransferase: 3-monooxygenase: topoisomerase ADP-dependent carboxylase/ reductase transporter monoglutamate hydroxymethylpyrimidine pyridoxamine 5'- phosphate a [prolipoprotein]- glucose-6- phosphoglucosamine CTZ40_RS05505 phosphate yl)-hydroquinone ACP synthase II: ACP synthase II: ACP synthase II: carrier-protein] carrier-protein] carrier-protein] cyclic-nucleotide 2'- cobaltochelatase CoA kinase: adenosyltranferase] molybdopterin synthase] CTZ40_RS34210 dehydratase: protein: CTZ40_RS26665 CTZ40_RS11955 CTZ40_RS11955 CTZ40_RS04165 CTZ40_RS21810 CTZ40_RS01840 IV subunit A: reductase: of a sugar nicotinate-nucleotide kinase/ phosphate oxidase: dihydroxybenzoate S-1,2-diacyl-sn- phosphate mutase: [+ 2 isozymes] isomerase, CTZ40_RS33630 CTZ40_RS33630 adenylate synthase: CTZ40_RS33630 reductase: fabG reductase: fabG reductase: fabG phosphodiesterase/ NAD(P)H-hydrate FabI: fabI subunit CobN: cobN CTZ40_RS31090 cob(I)yrinic acid bifunctional 5-deoxy-D-glucuronate CTZ40_RS31560 CTZ40_RS14195 CTZ40_RS39440 6-phospho-beta- CTZ40_RS09915 dehydratase/ ccrA adenylyltransferase: phosphomethylpyrimidine CTZ40_RS19370 3-dehydroquinate dehydrogenase: glyceryl-L-cysteine isomerase: CTZ40_RS22435 class I: manA beta-ketoacyl- beta-ketoacyl- carboxylesterase/ beta- carboxylesterase/ uracil-DNA demethylmenaquinone 4-hydroxybenzoate 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP 5'-nucleotidase/ enoyl-ACP cob(II)yrinate a [lipoyl-carrier protein] a,c-diamide uroporphyrinogen-III 2,5- D-glyceraldehyde [+ 3 isozymes] predicted CTZ40_RS27140 kinase: thiD [+ 5 isozymes] CTZ40_RS09370 CTZ40_RS31335 α-D-glucosamine F6P ACP synthase ACP synthase (2,3-dihydroxybenzoyl) glucosidase: lipase family protein: ketoacyl- lipase family protein: glycosylase: methyltransferase: 3-monooxygenase: reductase: reductase: reductase: 3'-nucleotidase: type I DNA NAD(P)H-hydrate crotonyl-CoA reductase cobyrinate a,c-diamide coenzyme A N 6 -octanoyl-L-lysine adenosyltransferase: C-methyltransferase/ aspartate- 5-deoxy-glucuronate dioxopentanoate 3-phosphate 2,3,6- a mature peptidoglycan ABC type II 3- 2,3- signal 1-phosphate a nascent peptidoglycan II: fabF II: fabF adenylate synthase: CTZ40_RS27385 CTZ40_RS37930 ACP CTZ40_RS37930 CTZ40_RS35990 CTZ40_RS07665 CTZ40_RS08090 CTZ40_RS28785 CTZ40_RS28785 CTZ40_RS28785 CTZ40_RS30965 topoisomerase: epimerase: carboxylase/ FabI: fabI a sugar a sugar nicotinate adenine a 7,8-dihydrofolate CTZ40_RS12430 isomerase: iolB beta-N- trichlorohydroquinone with (L-alanyl-γ-D-glutamyl- D-glucopyranose an apyrimidinic lipoyl HMP-P uroporphyrinogen- PLP -tRNA dehydroquinate dihydroxybenzoate peptidase F6P glyceraldehyde- (meso-DAP containing) a cis-delta15-3- a cis,cis-delta17,29- CTZ40_RS09360 a cis,cis-delta15,33- a cis,cis-delta19,31- a cis-delta13-3- topA CTZ40_RS22460 reductase: a (2E)-oct- transporter cobyrinate a,c- tetrapyrrole biosynthesis dinucleotide molybdopterin asp meso-2,6-diaminopimeloyl- acyl-carrier protein acyl-carrier protein D-glucopyranose MeOH (indol-3-yl)acetate synthase palmitate a retinol uracil menaquinol-12 protocatechuate cob(I)yrinic acid III synthase: ligase: II: lspA bifunctional UDP-N- 3-phosphate D-galactose degradation I (Leloir pathway) acetylhexosaminidase: oxo-C34:1-[acp] 3-oxo-C48:2-[acp] (2,3-dihydroxybenzoyl)adenylate 6-phosphate site in DNA 3-oxo-C52:2-[acp] 3-oxo-C50:2-[acp] hydroxyC32:1-[acp] guanosine 2-enoyl-[acp] of a sugar diamide synthase: folate transformations I synthase: lipA dehydratase: aroQ 5-dehydro-2-deoxy-D-gluconate with GlcNAc terminus II: fabF a relaxed DNA (S)-NADPHX ccrA II (from glycine) NAD+ synthase: a,c-diamide bifunctional 5-(2-hydroxyethyl) CTZ40_RS21400 molybdopterin aspS an L-aspartyl- 6-phosphofructokinase: acetylglucosamine dehydrogenase: CTZ40_RS07650 D-alanine) tetrapeptide a (7Z)-3- (2S)- CTZ40_RS01260 a [lipoyl-carrier signal peptidase II: NAD+ synthase: CTZ40_RS29610 hydroxymethylpyrimidine -4-methylthiazole adeninyl adenosylcobamide asp 3-dehydroshikimate CTZ40_RS12160 diphosphorylase/ acyl-carrier protein oxohexacos- protein]-N 6 -[(R)- adenosyltransferase: uroporphyrinogen- adenylyltransferase: [tRNA ] CTZ40_RS30545 5-dehydro-2- 2-oxoglutarate CTZ40_RS04135 β-D-galactopyranose beta-N- 2,6-dichloro-3- ethylmalonyl-CoA predicted cobyrinate a,c- gly CTZ40_RS29610 ammonia- a tetrahydrofolate cobO kinase/ biosynthesis from CTZ40_RS23975 tRNA asp [+ 2 isozymes] glucosamine-1- deoxygluconokinase: iolC acetylhexosaminidase: (glutathion-S-yl) 7-enoyl-[acp] ABC a tetrahydrofolate dihydrolipoyl]-L-lysine III synthase: shikimate a sugar a sugar diamide synthase: dependent phosphomethylpyrimidine adenosylcobinamide-GDP an (S-diacyl-sn- β-D-fructose 1,6- phosphate N- 13-DPG aldose epimerase: CTZ40_RS25435 transporter CTZ40_RS25340 molybdopterin dehydrogenase: a lipoprotein 5-dehydro-2-deoxy-D- N,N'- N,N',N''- -hydroquinone CTZ40_RS31690 adenosylcobalamin kinase: thiD acetyltransferase CTZ40_RS20750 of a sugar NAD(+) 4-methyl-5-(2- adenine dinucleotide glyceryl)-L-cysteinyl- bisphosphate gluconate 6-phosphate diacetylchitobiose triacetylchitotriose ditrans,octacis- 3-amino-4- a 1-acyl-sn glycine CTZ40_RS34195 signal peptide GlmU: glmU a cis,cis-delta13,25- a 2,3,4-saturated a 2,3,4-saturated 2- a (3Z)-docos- a cis,cis-delta13,31-3- a cis,cis-delta17,29- a cis-delta11-3- an L-asparaginyl- (2E,6E)-farnesyl cob(II)yrinate 5-aminolevulinate synthetase: formyltetrahydrofolate uroporphyrinogen-III adenine [apolipoprotein] phosphoglycerate a cis-delta11-C30:1-[acp] a malonyl-[acp] a malonyl-[acp] an all-trans-retinyl ester all-trans-retinyl palmitate a malonyl-[acp] (-)-methyl jasmonate 3-phenylpropanoate DMKH2-13 -glycerol 3- a cerotoyl-[acp] phosphooxyethyl) molybdopterin α-D-galactopyranose beta-N- undecaprenyldiphospho-N- hydroxybenzaldehyde Asn cleavage HMP-PP N-acetyl-α-D- kinase: C44:2-[acp] fatty acyl-[acp] lysophosphatidate 3-enoyl-[acp] hydroxy C50:2-[acp] 3-hydroxyC48:2-[acp] oxo-C30:1-[acp] [tRNA ] GTP diphosphate a,c-diamide nadE deformylase: purU thiazole nicotinate-nucleotide-- tyrosine- shikimate apolipoprotein N- class II fructose- acetylhexosaminidase: acetyl-(N-acetylglucosaminyl) D-aspartate beta-ketoacyl- beta-ketoacyl- carboxylesterase/ carboxylesterase/ beta-ketoacyl- carboxylesterase/ bifunctional 3- demethylmenaquinone arylamine N- 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- phosphate enoyl-ACP predicted system molybdotransferase tyr CTZ40_RS31315 1-acyl-sn-glycerol- aminoacyl-tRNA 1-acyl-sn-glycerol- squalene porphobilinogen 2-methyladeninyl dimethylbenzimidazole acyltransferase: lnt bisphosphate glucosamine 2,6-dichlorohydroquinone muramoyl-L-alanyl-γ-D- lipase family protein: lipase family protein: lipase family protein: phenylpropionate/ methyltransferase: acetyltransferase: ABC NAD + protein MoeA: -tRNA galactokinase: CTZ40_RS25435 ACP synthase II: ACP synthase II: 3-phosphate ACP synthase II: carrier-protein] carrier-protein] carrier-protein] hydrolase: bifunctional 3-phosphate synthase reductase a sugar a sugar adenosylcobamide biosynthesis phosphoribosyltransferase: shikimate kinase: aldolase: 1-phosphate 3-phospho- CTZ40_RS37930 CTZ40_RS11955 CTZ40_RS21810 CTZ40_RS17465 transporter synthase: hemB GcvH: thiamine CTZ40_RS19985 ligase: tyrS an L-tyrosyl- apolipoprotein N- galK beta-N- isoglutaminyl-L-lysyl-D-alanineD-aspartate ligase: CTZ40_RS33630 CTZ40_RS33630 acyltransferase: CTZ40_RS11955 CTZ40_RS33630 cinnamic acid reductase: fabG reductase: fabG reductase: fabG CTZ40_RS16170 diguanylate cyclase/ acyltransferase: HpnC: hpnC FabI: fabI 5-methoxy-6-methylbenzimidazolyl cobT CTZ40_RS34205 a peptide CTZ40_RS06015 3-oxopropanoate D-glycerate of a sugar phosphate from adenosylcobinamide-GDP Tyr acyltransferase: lnt bifunctional UDP-N- melibiose degradation ditrans,octacisCTZ40_RS21935- CTZ40_RS06430 carboxylesterase/ carboxylesterase/ carboxylesterase/ dioxygenase demethylmenaquinone arylamine N- phosphodiesterase: gcvH adenosylcobamide biosynthesis 5-methoxybenzimidazolyl molybdopterin [tRNA ] an N-acyl-(S-diacyl- acetylhexosaminidase: beta-ketoacyl- beta-ketoacyl- beta- 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP aminoacyl-tRNA CTZ40_RS06430 presqualene enoyl-ACP NAD salvage porphobilinogen a 10- synthase: nicotinate-nucleotide-- Tyr acetylglucosamine α-D-galactose undecaprenyldiphospho-N-acetyl- 2-methyladenine a tRNA shikimate 3- class II fructose- UDP-α-D-glucose CTZ40_RS07650 ACP synthase ACP synthase [+ 7 isozymes] lipase family protein: lipase family protein: ketoacyl- lipase family protein: ferredoxin subunit: methyltransferase: acetyltransferase: reductase: reductase: reductase: hydrolase: CTZ40_RS11660 reductase glycine formyltetrahydrofolate from adenosylcobinamide-GDP adenosylcobamide biosynthesis molybdotransferase sn-glyceryl)-L- DHAP 1-phosphate a 2,3,4-saturated a 1-acyl-2-[+ 7 isozymes] diphosphate predicted pathway III (to CTZ40_RS30370 dimethylbenzimidazole bisphosphate diphosphorylase/ malonate semialdehyde melibiose (N-acetylglucosaminyl)muramoyl- II: fabF II: fabF CTZ40_RS37930 CTZ40_RS11955 CTZ40_RS37930 CTZ40_RS35560 CTZ40_RS07665 CTZ40_RS27240 CTZ40_RS28785 CTZ40_RS28785 CTZ40_RS28785 diguanylate cyclase: FabI: fabI hydroxymethylbilane methionine cleavage 5-methoxy-6- from adenosylcobinamide-GDP nicotinate-nucleotide-- MoeA: phosphate cysteinyl-[lipoprotein] N-acetyl-D- 2-chloromaleylacetate 1,2-diacyl-sn ACP CTZ40_RS24375 palmitoyl-sn synthase nicotinamide riboside) phosphoribosyltransferase: aldolase: fbaA glucosamine-1- alpha-glucosidase/ L-alanyl-γ-D-isoglutaminyl-N-(β- a cis-delta13-3- a cis,cis-delta15,27- acyl-carrier protein 3-(5,6-dihydroxycyclohexa- 3-acetylamino-4- a cis,cis-delta13,31- a cis,cis-delta17,29- a cis-delta11-3- a trans-hexacos- ABC synthase: hemC synthase: methylbenzimidazole dimethylbenzimidazole CTZ40_RS23965 dehydrogenase: 2-phospho- glucosamine a fatty acid all-trans-retinol palmitate all-trans-retinol synthase MeOH (-)-jasmonate menaquinol-13 Asn CTZ40_RS08065 a sugar a sugar system bifunctional a (6S)-5- 5-methoxybenzimidazole cobT 3-phosphoshikimate 1- phosphate N- D-asparatyl)-L-lysyl-D-alanine acyl-carrier protein acyl-carrier protein -glycerol 3- 1,3-dien-1-yl)propanoate hydroxybenzaldehyde tRNA asn -glycerol 3- HpnD: hpnD transporter NADP + nicotinate-nucleotide-- thiamine phosphoribosyltransferase: CTZ40_RS26430 alpha-galactosidase: oxo-C32:1-[acp] 3-oxo-C46:2-[acp] II: fabF 3-oxo-C50:2-[acp] 3-oxo-C48:2-[acp] hydroxyC30:1-[acp] c-di-GMP 2-enoyl-[acp] [+ 2 isozymes] CTZ40_RS11670 protein methylenetetrahydrofolate adenine ribotide MoO -molybdopterin carboxyvinyltransferase: D-glycerate phosphate a (5Z)-3- phosphate squalene formyltetrahydrofolate dimethylbenzimidazole phosphate nicotinate-nucleotide-- 2 acetyltransferase CTZ40_RS33550 of a sugar cobT phosphate tryptophan- methionine GcvH: dehydrogenase/ phosphoribosyltransferase: dimethylbenzimidazole cofactor CTZ40_RS36740 triosephosphate GlmU: glmU phosphopyruvate acyl-carrier protein oxotetracos- preuroporphyrinogen thiamine- nicotinate-nucleotide-- -tRNA 5-oxo-L-proline metabolism alpha-galactosidase: synthase: gcvH methenyltetrahydrofolate 5-formyltetrahydrofolate cobT phosphoribosyltransferase: a tRNA Trp 3-phosphoshikimate 1- isomerase: UDP-N-acetyl- acetyl-CoA hydratase: 5-enoyl-[acp] a purine RS07735 a purine + phosphate kinase: dimethylbenzimidazole adenosylcobinamide- trans, trans-farnesyl ligase: trpS CTZ40_RS34715 5-chloro-3-oxoadipate NAD bifunctional metH cyclohydrolase: cyclo-ligase: cobT carboxyvinyltransferase: CTZ40_RS05195 α-D-glucosamine CTZ40_RS01275 nicotinate-nucleotide-- CTZ40_RS11220 phosphoribosyltransferase: GDP diphosphate [+ 2 isozymes] an L-tryptophanyl- a [protein] with a [protein] with D-galactopyranose D-glucopyranose uroporphyrinogen-III bifunctional bifunctionalCTZ40_RS15315 CTZ40_RS23955 aroA triose-phosphate D-glucarate degradation I phosphopyruvate chitobiose degradation α NAD(+) nicotinate-nucleotide-- Trp an N-terminal an N-terminal UDP-N-acetylglucosamine UDP-N-acetyl- -D-muramoyl-L- a 1-acyl-sn a [protein]-L- a 1-acyl-sn (S)-1-pyrroline- methylenetetrahydrofolate dimethylbenzimidazole thiamine cobT ribazoletransferase: biosynthesis [tRNA ] 5-enolpyruvoyl- a cis,cis-delta11,23- an acyl-[acyl- a 7,8-dihydro-8- an acyl-[acyl- a (5Z)-tetradec- chitin D-glycero-β-D- 1-(18-hydroxyoleoyl)- a cis,cis-delta11,29-3- a cis,cis-delta15,27- an L-cysteinyl- C-methyltransferase/ methylenetetrahydrofolate 5-hydroxybenzimidazolyl isomerase: 1-carboxyvinyltransferase: hydratase: alanyl-γ-D-glutamyl-meso-2,6- a malonyl-[acp] a malonyl-[acp] -glycerol 3- a malonyl-[acp] a malonyl-[acp] β -glycerol 3- nitrite a decanoyl-[acp] diphosphatase: phosphoribosyltransferase: dimethylbenzimidazole CTZ40_RS29995 trp L-glutamine L-glutamate N,N'- ATP cob(II)inamide oxoguanine in DNA Cys -isoaspartate 5-carboxylate a purine RS07745 a purine uroporphyrinogen- serine dehydrogenase/ dehydrogenase/ a 5,10- diphosphate 2-methyladenine Coα-[α-(adenin- adenosylcobamide biosynthesis shikimate 3- CTZ40_RS31320 CTZ40_RS24510 C42:2-[acp] carrier protein] carrier protein] 5-enoyl-[acp] beta-N- manno-heptose ATP sn-glycrol 3-phosphate hydroxy C48:2-[acp] 3-hydroxyC46:2-[acp] [tRNA ] nudC cobT phosphoribosyltransferase: IPP D-glyceraldehyde CTZ40_RS08800 D-glucarate diaminopimeloyl-D-alanyl-D-alanine beta-ketoacyl- beta-ketoacyl- bifunctional DNA- 1-acyl-sn-glycerol-phosphate beta- beta-ketoacyl-ACP 1-acyl-sn-glycerol- 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- aminoacyl-tRNA protein-L- phosphate L-glutamate respiratory enoyl-ACP hydroxymethyltransferase: methenyltetrahydrofolate 5-methoxy-6- β phosphate DHAP diacetylchitobiose D-alanyl-D-alanine 1-phosphate 1-acyl-sn-glycerol- III synthase: methenyltetrahydrofolate methenyltetrahydrofolate cobT ribotide phosphate 9-yl)]-Co - from adenosylcobinamide-GDP isopentenyl- 3-phosphate phosphoenol 2-maleylacetate cob(I)yrinic acid a,c-diamide formamidopyrimidine acetylhexosaminidase: synthase II: fabF isoaspartate(D- gamma- nitrate reductase: methylbenzimidazole chorismate UDP-N-acetylglucosamine glucarate 6'-phosphate carboxypeptidase/ ACP synthase II: ACP synthase 3-phosphate ketoacyl- D-glycero-beta-D- 3-phosphate carrier-protein] carrier-protein] hydrolase: 3-phosphate reductase NMN CTZ40_RS21400 CTZ40_RS12510 cyclohydrolase: cyclohydrolase: 5-methoxybenzimidazole adenosylcobamide diphosphate pyruvate adenosyltransferase: cobO CTZ40_RS25435 aspartate) O- semialdehyde 5-hydroxybenzimidazole NaMN glyceraldehyde- 1-carboxyvinyltransferase: D-alanyl-D-alanine- CTZ40_RS33630 II: fabF glycosylase/ acyltransferase: ACP manno-heptose beta-ketoacyl- acyltransferase: reductase: fabG reductase: fabG CTZ40_RS16170 acyltransferase: CTZ40_RS36830 FabI: fabI Co 2+ Co 2+ [+ 2 isozymes] CTZ40_RS15315 CTZ40_RS15315 ribotide phosphate ribotide phosphate adenosylcobinamide- 5'-phosphate synthase: dehydratase: RS28315 Delta-isomerase: a [protein] with N-monoacetylchitobiose cob(I)yrinic acid a,c-diamide DNA-(apurinic beta-N- methyltransferase: dehydrogenase: narH narI 2+ 2+ uroporphyrinogen- adenosylcobinamide- nicotinate-nucleotide-- threonine-- 3-phosphate murA pyruvate UDP-glucose endopeptidase: dacB beta-ketoacyl- beta-ketoacyl- CTZ40_RS11245 synthase 1-phosphate ACP synthase II: CTZ40_RS06430 3-oxoacyl-ACP 3-oxoacyl-ACP aminoacyl-tRNA CTZ40_RS06430 enoyl-ACP Ni Ni bifunctional GDP aroC CTZ40_RS27370 α pruA III synthase: GDP NAD salvage pathway I (PNC VI cycle) adenosylcobinamide- dimethylbenzimidazole CTZ40_RS05760 an N-terminal 5- dehydrogenase: α kinase: pyk UDP-glucose: - 6'-phosphate fructose degradation adenosyltransferase: ACP synthase ACP synthase II: or apyrimidinic [+ 7 isozymes] II: fabF acetylhexosaminidase: adenylyltransferase: CTZ40_RS33630 [+ 7 isozymes] reductase: reductase: CTZ40_RS18555 CTZ40_RS36860 reductase metallophosphatase/ ribazoletransferase: tRNA ligase: UDP-N-acetyl- - 5-dehydro-4- 4-epimerase penicillin-binding a 1,2-diacyl- 1-[18-hydroxyoeoyl]-2- hydrolase: a 1-acyl-2-[+ 7 isozymes] CTZ40_RS25340 ribazoletransferase: GDP phosphoribosyltransferase: DMAPP chorismate oxo-L-proline γ-L-glutamyl CTZ40_RS04135 pyruvate D-galactose- 6-phospho-beta- CTZ40_RS12430 II: fabF CTZ40_RS33630 site) lyase: mutM CTZ40_RS07650 rfaE2β CTZ40_RS28785 CTZ40_RS28785 [+ 2 isozymes] narH narI FabI: fabI 5'-nucleotidase: CTZ40_RS29995 CTZ40_RS34010 D-glucosamine- deoxy-D-glucarate GalE: galE 3-oxoadipate UDP-N-acetylmuramoyl-L-protein 2: mrdA acyl-carrier protein sn-glycerol beta-ketoacyl- N-acetyl-D- ADP-D-glycero- - a 3-oxodocosanoyl-[acp] [18-hydroxy-lioleoyl]-sn CTZ40_RS24375 a protein L-β- arachidonoyl- glu a 5,10- + ribazoletransferase: α α Coα-[α-(adenin- glutathione 1-phosphate β triphosphate adenosylcobinamide an apurinic site 7,8-dihydro- CTZ40_RS29995 Co -[ -(2- cobT 5-phosphate enolpyruvate kinase: pyk glucosidase: -D-fructofuranose a cis,cis-delta13,25- chitin a cis,cis-delta11,29- a cis,cis-delta15,27- Cys [+ 2 isozymes] a (2E)-dec- 2+ 2+ CTZ40_RS16415 uroporphyrinogen-III a 5-methyltetrahydrofolate folate polyglutamylation NAD prenyltransferase threonine- pyroglutamyl- UDP-glucose D-ala alanyl-γ-D-glutamyl-meso-2,6- acyl-carrier protein acyl-carrier protein a 3-oxoacyl-[acp] 3-phosphate ACP synthase II: glucosamine D-manno-heptose -glycerol 3-phosphate a tRNA cys isoaspartate sn-glycerol Ni RS32620 Ni methylenetetrahydrofolate Coα-[α-(5-methoxy-6- CTZ40_RS29995 methyladenin-9-yl)]-Co 7-yl)]-Coβ- thr 13-DPG uridylyltransferase: CTZ40_RS26665 1-phosphate 3-oxo-C44:2-[acp] within DNA 8-oxoguanine 3-oxo-C48:2-[acp] 3-oxo-C46:2-[acp] 2-enoyl-[acp] [+ 2 isozymes] nicotinate-nucleotide-- UbiA: -tRNA peptidase UDP-N- 4-epimerase diaminopimeloyl-D-alanine CTZ40_RS33630a (7Z)-3-oxo- α-methyl ester 3-phosphate nitrate methylbenzimidazolyl)]- Coα-[α-(5- β-adenosylcobamide adenosylcobamide pyruvate α-D-glucopyranose galT 1-phosphofructokinase: 1-(β-D NAD(+) dimethylbenzimidazole CTZ40_RS38200 ligase: thrS an L-threonyl- I: pcp acetylmuramate α GalE: galE 6-phospho-beta- acyl-carrier protein hexadec-7- methylenetetrahydrofolate a tetrahydrofolate Coβ-adenosylcobamide methoxybenzimidazolyl) 5'-phosphate phosphoglycerate 1-phosphate UDP- -D-galactose pfkB ribofuranosyl) diphosphatase: phosphoribosyltransferase: Thr dehydrogenase: glucosidase: β-D-fructose 1,6- reductase [NAD(P)H]: metF 5'-phosphate ]-Coβ-adenosylcobamide geranyl [tRNA ] kinase: tartronate enoyl-[acp] glycine glycine nicotinamide nudC cobT Thr CTZ40_RS22125 pyruvate D-lactate CTZ40_RS27385 bisphosphate RS25495 NAD+ synthase: 5'-phosphate diphosphate a tRNA CTZ40_RS31315 semialdehyde phosphomannomutase/ betaine betaine biotin biosynthesis from 5-hydroxybenzimidazole 5-oxo-L-proline dehydrogenase: N-acetyl-D- serine bifunctional nicotinate adenine UDP-N- phosphoglucomutase: tetrahydrofolate salvage from 8-amino-7-oxononanoate I CTZ40_RS29610 NMN Coα-[α-(2- ribotide phosphate prenyltransferase 3-phospho- 2-hydroxy-3- glucosamine D-glucosamine a peptidoglycan dimer (meso N-acetyl-muramoyl-(L- 1-stearoyl- a DNA methyl a [protein]- a 3-methyl- DNA with adenine:7,8- 3-oxo-2-(cis-2'-pentenyl) an N-hydroxy- 1-myristoyl- a (2E,7Z)- hydroxymethyltransferase: folylpolyglutamate queuosine biosynthesis acetylmuramate vanH a cis,cis-delta9,21- an acyl-[acyl- a (3Z)-dodec- a (9Z)-3-oxo- a cis,cis-delta13,25- an aliphatic amine 5,10-methenyltetrahydrofolate α α dinucleotide UbiA: 5-oxoprolinase D-glycerate (S)-lactate CTZ40_RS24985 -diaminopimelate containing) a malonyl-[acp] alanyl-γ-D-glutamyl-L- sn-glycerol a malonyl-[acp] branched glycerophosphoglycerol dihydro-8- -cyclopentane-1-(3R- sn-glycerol butan-1-ol leu hexadeca-2,7- CTZ40_RS12510 Co -[ -(5-methoxy-6- methyladenin-7-yl)]-Co adenosylcobinamide- oxopropionate 6-phosphate ATP cob(II)alamin phosphotriester L-cysteine 2-oxoglutarate 3-hydroxyC44:2-[acp] arylamine NAD salvage pathway II (PNC IV cycle) synthase/ a 10- nicotinate-nucleotide α α subunit dehydrogenase: D-alanyl-D-alanine C40:2-[acp] lysyl-D-alanyl-D-alanine) carrier protein] 3-phosphate methylated-DNA-- 3-enoyl-[acp] oxoguanine mismatch hydroxyhexanoyl)-CoA octadec-9-enoyl-[acp] arylamine N- copper amine 3-phosphate NAD(P)- dienoyl-[acp] leu RS17295 leu 8-amino-7-oxononanoate methyl-benzimidazolyl)]- Co -[ -(5- β-adenosylcobamide GDP ribazoletransferase: CTZ40_RS38200 phosphoglyceromutase: reductase: D-glucopyranose beta-ketoacyl- D-alanyl-D-alanine 1-acyl-sn-glycerol- beta- 2,3,4-saturated glycerophosphoryl A/G-specific crotonase/enoyl- 3-oxoacyl-ACP 3-oxoacyl-[acyl- 1-acyl-sn-glycerol- amino acid enoyl-ACP a 5,10- [+ 2 isozymes] dihydrofolate formyltetrahydrofolate serine- preQ PxpB: pxpB CTZ40_RS39485 (R)-lactate cob(I)yrinic acid a,c-diamide carboxypeptidase/ phytanoyl-CoA adenosylmethionine--8- Coβ-adenosylcobamide adenylyltransferase: methoxybenzimidazolyl) CTZ40_RS29995 0 CTZ40_RS07780 ACP synthase II: [protein]-cysteine S- fatty acyl-CoA diester reductase: carrier-protein] acetyltransferase: oxidase: dependent alcohol racemase: reductase methenyltetrahydrofolate synthase: (2E,6E)-farnesyl -tRNA CTZ40_RS16340 6-phosphate carboxypeptidase/ 3-phosphate ketoacyl- adenine CoA hydratase 3-phosphate bifunctional NAD + CTZ40_RS27140 ]-Coβ-adenosylcobamide UDP-N-acetyl- adenosyltransferase: D-alanyl-D-alanine- methyltransferase: dioxygenase: CTZ40_RS17465 CTZ40_RS08425 dehydrogenase: amino-7-oxononanoate bifunctional α α diphosphate ser [+ 2 isozymes] CTZ40_RS33630 D-alanyl-D-alanine- acyltransferase: ACP phosphodiesterase: glycosylase: family protein: CTZ40_RS28785 reductase: fabG acyltransferase: CTZ40_RS34785 FabI: fabI NAD(+) a 5,10- CTZ40_RS27005 Co -[ -(5-hydroxybenzimidazolyl)]- ligase: glu 2-phospho- α-D-muramate CTZ40_RS12430 endopeptidase: dacB CTZ40_RS39885 methylenetetrahydrofolate transaminase: folylpolyglutamate CTZ40_RS31160 CTZ40_RS34580 arylamine N- primary-amine CTZ40_RS07305 2+ 2+ diphosphatase: methylenetetrahydrofolate Coβ-adenosylcobamide 5'-phosphate serS beta-ketoacyl- endopeptidase: dacB CTZ40_RS11245 synthase a 2-hydroxy-3- CTZ40_RS16990 CTZ40_RS05300 3-oxoacyl-[acyl- 3-oxoacyl-ACP CTZ40_RS06430 amino-acid enoyl-ACP Co RS24205 Co dehydrogenase/ nicotinamide an L-seryl- D-glycerate (R)-glycerate penicillin-binding [+ 2 isozymes] CTZ40_RS37240 synthase/ NaMN menaquinol-7 biosynthesis menaquinol-11 biosynthesis preQ cob(I)yrinic acid a,c-diamide ACP synthase [+ 7 isozymes] [+ 2 isozymes] II: fabF [+ 6 isozymes] an apurinic site carrier-protein] reductase: acetyltransferase: oxidase: [+ 4 isozymes] racemase: reductase NAD+ synthase: nudC [tRNA ser ] 1 penicillin-binding a 1-stearoyl 2- a [protein]-S- methyl-branched 3-oxo-2-(cis-2'-pentenyl)[+ 5 isozymes] 1-myristoyl-2-[+ 7 isozymes] methenyltetrahydrofolate 7,8-diaminopelargonate bifunctional a tetrahydrofolate dihydrofolate thioredoxin nicotinamidase: phosphopyruvate adenosyltransferase: cobO protein 2: mrdA succinate sn-glycerol adenine CTZ40_RS27240 CTZ40_RS32870 CTZ40_RS29610 menaquinol-10 biosynthesis ser II: fabF [DNA] glycerol within DNA reductase: fabG CTZ40_RS28785 butan-1-al CTZ40_RS11065 FabI: fabI folylpolyglutamate CTZ40_RS25575 a tRNA hydratase: a peptidoglycan with N-acetyl-muramoyl-(L-protein 2: mrdA acyl-carrier protein acyl-sn-glycerol methyl-L-cysteine beta-ketoacyl- 2,3,4-saturated -cyclopentane-1-(E- an N- palmitoleoyl- cyclohydrolase: synthase: pathway all-trans- all-trans- UDP-N-acetyl- C1 Compound Utilization and Assimilation triphosphate adenosylcobalamin a cis,cis-delta11,23- 3-phosphate a (3R,9Z)-3-hydroxy- a cis,cis-delta13,25- an aldehyde a (7Z)-hexadec- ATP-dependent 1,4-dihydroxy- 1,4-dihydroxy- thiamine diphosphate D-ala D,D cross-links (meso- acyl-carrier protein D-ala alanyl-γ-D-glutamyl- 3-phosphate ACP synthase II: fatty acyl-CoA hexa-2-enoyl)-CoA sn-glycerol D-leucine 2+ 2+ CTZ40_RS15315 synthase/ CTZ40_RS27005 all-trans- heptaprenyl undecaprenyl CTZ40_RS01275 3-oxo-C42:2-[acp] octadec-9-enoyl-[acp] 3-oxo-C44:2-[acp] acetoxyarylamine 7-enoyl-[acp] Co RS24210 Co 1,4-dihydroxy- nicotinate 2-naphthoate 2-naphthoate Coα-[α-(5-hydroxybenzimidazolyl) α-D-muramoyl- CTZ40_RS33630 a 10- dethiobiotin nicotinate adenine dihydrofolate an oxidized diphosphate diphosphate biosynthesis I (E. coli) diaminopimelate containing) L-lysyl-D-alanine) a (5Z)-3-oxo- 3-phosphate NMN a 10- decaprenyl phosphoribosyltransferase: ]-Coβ-adenosylcobamide a 7-aminomethyl-7- phosphopyruvate L-alanyl-γ-D- 2-phospho- formyltetrahydrofolate synthetase BioD: bioD 2-naphthoate 34 formaldehyde oxidation acyl-carrier protein tetradec-5- dinucleotide synthase: diphosphate thioredoxin deazaguanosine hydratase: D-glycerate formaldehyde oxidation formyltetrahydrofolate CTZ40_RS25580 di-trans,poly-cis-undecaprenyl demethylmenaquinol-7 DMKH2-11 HMP-PP glutamyl-meso-2,6- VII (THF pathway) formaldehyde formaldehyde phosphoribosylglycinamide CTZ40_RS27005 nicotinate proline-- in tRNA CTZ40_RS24510 II (glutathione-dependent) enoyl-[acp] dethiobiotin phosphate biosynthesis thiamine diaminopimelate oxidation III oxidation V Na + RS38600 Na + formyltransferase: DMKH2-10 tRNA ligase: S-adenosylmethionine:tRNA a 5,10- demethylmenaquinone demethylmenaquinone phosphate phosphoenol formaldehyde (mycothiol-dependent) (bacillithiol-dependent) CTZ40_RS15335 nicotinate-nucleotide thioredoxin- CTZ40_RS10650 formaldehyde biotin synthase methylenetetrahydrofolate (2E,6E)-farnesyl ribosyltransferase- a peptidoglycan a (2R)-2-hydroxy 1-myristoyl- UDP-N-acetyl- 1518 a 2'- 3-oxo-2-(cis-2'-pentenyl) a ribonucleoside 1-palmitoyl- demethylmenaquinone methyltransferase: methyltransferase: glutathione biosynthesis synthase: pyruvate + an electron- adenine / biotin RS26880 biotin adenylyltransferase: disulfide guanylyl molybdenum proline-- formaldehyde formaldehyde a peptidoglycan NADH H a ribonucleoside a cis,cis-delta11,23- DMKH an arylamine butan-1-ol a tetrahydrofolate BioB: bioB bis(guanylyl molybdenum lipoate biosynthesis methyltransferase: factor 420 diphosphate CTZ40_RS21810 CTZ40_RS21810 isomerase: CTZ40_RS31955 a (3Z)-dec-3-enoyl-[acp] a malonyl-[acp] dimer (S. aureus) even numbered a myristoyl-[acp] sn-glycerol transfer quinone α-D-muramoyl- di-trans,octa-cis 1519 deoxyribonucleoside [DNA] -cyclopentane-1-(3R- 2',3'-cyclic 2 sn-glycerol ser a behenoyl-[acp] CTZ40_RS30370 pro pyruvate adenine in 16S rRNA 5'-monophosphate + + CTZ40_RS27140 reductase: cofactor biosynthesis tRNA ligase: 34 Carboxylate Degradation N-acetylmuramoyl- D-alanyl-D-alanine 3-hydroxyC42:2-[acp] Na RS24300 Na cofactor) biosynthesis and incorporation I CTZ40_RS21810 polyglutamylation thiamine an epoxyqueuosine a 5,10- beta-ketoacyl- straight chain 1-acyl-sn-glycerol-3-phosphate NADH-quinone L-alanyl-γ-D- -undecaprenyl 16S rRNA 5'-triphosphate hydroxybutanoyl)-CoA phosphate 3-oxoacyl-[acyl- demethylmenaquinone arylamine N- 3-phosphate NAD(P)- amino acid enoyl-ACP NaMN demethylmenaquinone demethylmenaquinone kinase: pyk S-(hydroxymethyl) carboxypeptidase/ bifunctional bifunctional crotonase/enoyl- multifunctional 2',3'- 1-acyl-sn-glycerol- biotin trxB di-trans,octa-cis cys glu MoO - phosphate CTZ40_RS35615 an L-prolyl- in tRNA methylenetetrahydrofolate L-alanine amidase: ACP synthase 2,3,4-saturated oxidoreductase glutamyl-L- phosphate (adenine(1518)-N(6)/ carrier-protein] methyltransferase: acetyltransferase: dependent alcohol racemase: reductase menaquinol-6 biosynthesis MoO - demethylmenaquinone oxidized methyltransferase: methyltransferase: 2 pyruvate S-(hydroxymethyl) S-(hydroxymethyl) glutathione long-chain fatty 3-phosphate phospho-N- DNA primase/ metallophosphatase/ CoA hydratase cyclic-nucleotide 2'- 3-phosphate 2 -undecaprenyl molybdopterin Pro glycolate and CTZ40_RS11710 D-alanyl-D-alanine- fatty acid subunit D: adenine(1519)-N(6))- CTZ40_RS07665 dehydrogenase: menaquinol-8 biosynthesis molybdopterin methyltransferase: factor 420-0 CTZ40_RS07665 CTZ40_RS07665 glutamate--cysteine thiamine- [tRNA ] pyruvate fermentation pyruvate fermentation oxalate bifunctional mycothiol bacillithiol II: fabF acid--CoA ligase: acyltransferase: lysyl-D-alanine acetylmuramoyl- polymerase: 5'-nucleotidase: family protein: reductase: fabG CTZ40_RS17465 acyltransferase: CTZ40_RS34785 FabI: fabI an octanoyl-[acp] Pro 6 37 kinase: pyk pyruvate decarboxylation to acetyl CoA glutathione- endopeptidase: dacB phosphodiesterase/ coenzyme F420-0:L- diphosphate ligase GCS2: cofactor molybdenum cofactor a tRNA N -L-threonylcarbamoyladenosine glyoxylate [+ 5 isozymes] CTZ40_RS17145 dimethyltransferase demethylmenaquinone CTZ40_RS07305 cofactor CTZ40_RS07665 phosphate kinase: to acetate IV to acetate II degradation II superpathway of acetate methylenetetrahydrofolate S-(hydroxymethyl) S-(hydroxymethyl) ditrans,octacis- beta-ketoacyl- CTZ40_RS06710a (R)-2-hydroxy CTZ40_RS06430 pentapeptide- CTZ40_RS11100 CTZ40_RS16415 CTZ40_RS05300 5'-nucleotidase/ 3-oxoacyl-ACP arylamine N- CTZ40_RS06430 amino-acid enoyl-ACP potassium- geranyl diphosphate demethylmenaquinol-6 menaquinol-9 biosynthesis lipoyl(octanoyl) a reduced glutamate ligase: undecaprenyl- menaquinol-7 menaquinol-11 guanylyltransferase: -modified tRNA biosynthesis degradation I dependent penicillin-binding RsmA: rsmA CTZ40_RS35770 CTZ40_RS11220 pyruvate utilization and formation dehydrogenase/ ACP synthase II: [+ 7 isozymes] [+ 2 isozymes] transferase: 6 1518 reductase: methyltransferase: acetyltransferase: [+ 4 isozymes] racemase: reductase K + transporting K + demethylmenaquinol-8 transferase thioredoxin CTZ40_RS24935 a queuosine 34 a [pyruvate dehydrogenase mycothiol mycothiol formaldehyde a peptidoglycan undecaprenyldiphospho- [+ even10 isozymes] numbered 1,2-dimyristoyl- an electron- undecaprenyl- N -dimethyladenine [+ 14 isozymes] [+ 2 isozymes] 3-oxo-2-(cis-2'-pentenyl)[+ 5 isozymes] 3'-nucleotidase: 1-palmitoyl-2-[+ 7 isozymes] biosynthesis demethylmenaquinone menaquinol-10 diphosphate guanylyl CTZ40_RS19980 protein 2: mrdA + bis(molybdenum oxidized γ [+ 2 isozymes] glycolate pyruvate 6 pyruvate pyruvate oxalate methenyltetrahydrofolate CTZ40_RS33630 NAD CTZ40_RS30470 /N 6 -dimethyladenine 1519 CTZ40_RS30965 CTZ40_RS28785 CTZ40_RS21810 CTZ40_RS27240 butan-1-al CTZ40_RS11065 FabI: fabI ATPase demethylmenaquinone a [lipoyl-carrier LipB:protein] lipB -L-glutamyl- molybdenum thiamine in tRNA E2 protein] N -lipoyl-L-lysine dehydrogenase: dehydrogenase: dehydrogenase: pentapeptide N-acetyl-(N- diphosphate AMP straight chain acyl-carrier protein sn-glycerol transfer quinol diphospho-N- [DNA] a ribonucleoside -cyclopentane-1-(E- an N- palmitoleoyl- methyltransferase: demethylmenaquinol-9 cofactor) factor 420-1 phosphatase: thr dehydrogenase pyruvate a (5Z)-3-oxododec- a peptidoglycan with a ribonucleoside a cis,cis-delta11,23- a (2E)-docos- methyltransferase: 6 L-cysteine diphosphate acetate cyclohydrolase: CTZ40_RS27375 CTZ40_RS27375 acetylglucosaminyl)muramate 2,3,4-saturated 3-phosphate acetylmuramoyl- in 16S rRNA buta-2-enoyl)-CoA MQH IPP CTZ40_RS21810 demethylmenaquinone N -octanoyl-L-lysine CTZ40_RS36450 cofactor acetate--CoA CTZ40_RS08045 acyl-carrier protein D-ala 2 acetylarylamine sn-glycerol D-serine molybdenum cofactor F420-1:γ- phenylalanine-- threonylcarbamoyl- (acetyl- dehydrogenase: CTZ40_RS15315 5-enoyl-[acp] D,D cross-link (S. aureus) UMP γ 3'-phosphate 3-oxo-C42:2-[acp] 2-enoyl-[acp] CTZ40_RS21810 di-trans,octa-cis phe formate C- S-(hydroxymethyl) S-(hydroxymethyl) fatty acyl CoA L-alanyl- -D- 3-phosphate + + prenyltransferase demethylmenaquinone methyltransferase: lipoyl AMP synthase: pyruvate transferring), pyruvate CTZ40_RS07955 ligase: acs K RS26250 K guanylyltransferase: glutamyl ligase: tRNA ligase: pheS glycolysis I (from glucose 6-phosphate) oxalyl-CoA acetate kinase: a 5,10- S-formylglutathione glutamyl-L- UbiA: CTZ40_RS21810 demethylmenaquinone acyl carrier -undecaprenyl CTZ40_RS12520 glyoxylate acetyltransferase: dehydrogenase: mycothiol mycothiol methyltransferase: CTZ40_RS19980 synthase: lipA CTZ40_RS24935 CTZ40_RS33495 an L-phenylalanyl- (L-threonylcarbamoyl) homodimeric acetyl-CoA CTZ40_RS12170 methenyltetrahydrofolate lysyl- D-alanine CTZ40_RS38200 methyltransferase: protein activation phosphate pflB CTZ40_RS07955 dehydrogenase: dehydrogenase: geranyl CTZ40_RS07665 demethylmenaquinone bis(guanylyl a [lipoyl-carrier oxidized [tRNA Phe ] adenylate D-glucopyranose glyoxylate type: aceE oxalyl-CoA CTZ40_RS07665 6 glutathione [+ 2 isozymes] phosphate bifunctional CTZ40_RS35550 CTZ40_RS35550 2+ 2+ menaquinol-6 methyltransferase: molybdopterin) protein]-N -[(R)- a tRNA Phe decarboxylase: acetyl-CoA Co Co diphosphate menaquinol-8 factor 420-2 an apo acyl- tRNA (adenosine(37)-N6)- 6-phosphate carboligase: [+ 4 isozymes] acetyltransferase: acetyl phosphate RS33075 CTZ40_RS07665 cofactor dihydrolipoyl]-L-lysine CTZ40_RS06570 methylenetetrahydrofolate an odd numbered a 2-methyl 1-palmitoyl- a [glutamine 3-oxo-2-(cis- 3-oxo-2-(cis-2'-pentenyl) adenosine 3-amino-4- (2R,3S)-3- Mg 2+ Mg 2+ carrier protein threonylcarbamoyltransferase gcl acetyl-CoA formate S-formylmycothiol S-formylbacillithiol a cis- (4S)-4-hydroxy-2- a cis,cis-delta9,21-3- a dipeptide phytol CTZ40_RS12165 dehydrogenase/ pyruvate a cis-delta9-C28:1-[acp] a malonyl-[acp] straight chain branched 2,3,4- sn-glycerol a pimeloyl-[acp] synthetase]-O 2'-pentenyl)- 5'-deoxyadenosine -cyclopentane-1-(3R- 2',3'-cyclic lys a hexanoyl-[acp] menaquinol-9 holo-ACP synthase: glucose-6- tartronate formate vaccenoyl-[acp] ala oxoheptanedioate hydroxyC40:2-[acp] hydroxybenzoate isopropylmalate complex transferase a [pyruvate dehydrogenase a [pyruvate dehydrogenase formyl-CoA methenyltetrahydrofolate pyruvate, phosphate saturated fatty acid 4 arylamine N- 3-isopropylmalate membrane CTZ40_RS22455 phosphate phosphate beta-ketoacyl- 2,3,4-saturated fatty acid-- 1-acyl-sn-glycerol-3-phosphate 8-amino-7- -(5'-adenylyl) cyclopentane-1- S-methyl-5'- HpcH/HpaI hydroxyoctanoyl)-CoA monophosphate 3-oxoacyl-[acyl- NAD(P)- amino acid enoyl-ACP subunit TsaD: tsaD semialdehyde 6 6 acetyl phosphate crotonase/enoyl- multifunctional 2',3'- a holo acyl- acetyltransferase: E2 protein] N - E2 protein] N -S- phosphate cyclohydrolase: dikinase: CTZ40_RS07525 fatty acidfatty acid-- -L-tyrosine bifunctional [glutamine (3-oxooctanoyl) thioadenosine aldolase/ acetyltransferase: dehydratase: dipeptidase: dependent alcohol Co 2+ Co 2+ isomerase: pyruvate ACP synthase II: CoA ligase 3-phosphate oxononanoate CoA hydratase cyclic-nucleotide 2'- carrier-protein] racemase: reductase RS09115 methionine-- 2-hydroxy-3- formyl-CoA acetyltransferase: CTZ40_RS15315 CoA ligase acetyl-CoA C- leuD leuC CTZ40_RS24825 2+ 2+ carrier protein met tRNA (adenosine(37)-N6)- CTZ40_RS31335 CTZ40_RS12165 dihydrolipoyl-L-lysine acetyldihydrolipoyl-L-lysine pyruvate, phosphate CTZ40_RS33630 family protein: synthetase] -CoA phosphorylase: citrate lyase reductase: fabG CTZ40_RS27240 dehydrogenase: CTZ40_RS34785 FabI: fabI Mg Mg tRNA ligase: dehydrogenase: acetate kinase: CTZ40_RS12165 acyltransferase: synthase: acyltransferase: family protein: phosphodiesterase/ threonylcarbamoyltransferase oxopropionate transferase: frc L-malate a 10- formate formate dikinase: CTZ40_RS27600 family protein: adenylyltransferase/ 3-oxo-2-(cis- CTZ40_RS23930 family protein: arylamine N- 3-isopropylmalate membrane CTZ40_RS07305 an L-methionyl- CTZ40_RS07955 beta-ketoacyl- CTZ40_RS22880 CTZ40_RS06430 CTZ40_RS37250 CTZ40_RS08675 CTZ40_RS05300 5'-nucleotidase/ 3-oxoacyl-ACP amino-acid enoyl-ACP CTZ40_RS20250 complex transferase F6P reductase: acetyl phosphate CTZ40_RS12170 formyltetrahydrofolate CTZ40_RS22880 8-amino-7- [glutamine synthetase]- CTZ40_RS28235 acetyltransferase: dehydratase: dipeptidase: [+ 4 isozymes] [elongator degradation II ACP synthase [+ 11 isozymes] [+ 7 isozymes] acyl-carrier protein acetyl-CoA 2'-pentenyl)- 5-deoxy-α-ribose [+ 5 isozymes] 3'-nucleotidase: reductase: racemase: reductase subunit TsaD: tsaD CTZ40_RS37805 formate diphosphate AMP phosphoenolpyruvate H + an odd numbered a 2-methyl 1-palmitoyl-2- adenylyl-L-tyrosine adenine succinate 3-oxo-2-(cis-2'-pentenyl) Co 2+ Co 2+ elongator Met [+ 11 isozymes] oxononanoate cyclopentane-1- pyruvate CTZ40_RS17465 leuC leuD CTZ40_RS00370 phytenal tRNA ] 6 acetate formyltetrahydrofolate II: fabF acyl-carrier protein cis-vaccenoyl 1-phosphate -cyclopentane-1-(E- CTZ40_RS30965 CTZ40_RS28785 CTZ40_RS11065 FabI: fabI 2+ RS13070 2+ Met an N -L- straight chain branched phosphorylase: semialdehyde 3-acetylamino-4- (2S)-2- Mg Mg tRNA [+ 2 isozymes] acetate kinase: D-gluconate (S)-malate a cis-delta11-3- diphosphate AMP AMP diphosphate hexanoyl-CoA a cis,cis-delta9,21- a proteinogenic a (2E)-hex- L-histidine biosynthesis Amino Acid Biosynthesis threonylcarbamoyladenine 37 class II fructose- 6-phosphofructokinase: acetyl-CoA deformylase: purU acyl-carrier protein 2,3,4-saturated 2,3,4-saturated phosphatidate octa-2-enoyl)-CoA 3'-AMP D-lysine superpathway of branched chain amino acid biosynthesis L-lysine biosynthesis I L-threonine uracil degradation superpathway of L-cysteine L-tryptophan biosynthesis ammonia L-cysteine biosynthesis L-alanine CTZ40_RS12170 NAD-dependent oxo-C30:1-[acp] a [glutamine-CTZ40_RS29645 3-oxo-C40:2-[acp] hydroxybenzoate isopropylmalate amino acid 2-enoyl-[acp] L-arginine biosynthesis I (via L-ornithine) in tRNA bisphosphatase: CTZ40_RS12160 (R)-glycerate degradation fatty acyl CoA fatty acyl-CoA biosynthesis I (reductive) biosynthesis (mammalian) assimilation cycle III glycine biosynthesis III malic enzyme: VI (from L-methionine) glpX [+ 2 isozymes] formate ADP synthetase]- PRPP biosynthesis IV acetate CTZ40_RS26260 Co 2+ Co 2+ pyruvate uracil D-gluconate L-tyrosine RS13650 thr asp gln chorismate bifunctional pyruvate Mg 2+ Mg 2+ glu L-homoserine met ammonium glu cys β-D-fructose 1,6- gluconokinase: ATP met lysylphosphatidylglycerol acetolactate aspartate kinase: glutamine methionine thr cysteine bisphosphate CTZ40_RS14910 phosphoribosyltransferase: threonine homoserine kinase: anthranilate synthase DHAP 2-phospho- D-gluconate 1-cis-vaccenoyl- 1-palmitoyl- cytidine 2',3'-cyclic guanosine synthase: ilvN CTZ40_RS18065 amino-acid N- methionine synthetase: low specificity L- desulfurase: synthetase/lysine-- glyoxylate cycle class II fructose- (2E,6Z,9Z,12Z,15Z,18Z,21Z) 3-oxo-2-(cis- all-trans-3,4- a 1-alkyl-sn CTZ40_RS34500 ammonia-lyase: CTZ40_RS12550 adenosyltransferase: D-glycerate 6-phosphate 18-hydroxyoleate a cis,cis-delta19- glycerophosphoserine a (6S)-5- an unsulfurated a (9Z)-3-oxooctacos- salicyl-CoA CTZ40_RS11545 acetyltransferase: 5,6-dihydrouracil adenosyltransferase: component I: threonine aldolase: tRNA ligase LysX: lysX bisphosphate a malonyl-[acp] an oleoyl-[acp] a malonyl-[acp] a palmitoleoyl-[acp] sn-glycerol- a palmitoyl-[acp] sn-glycerol glu -tetracosaheptaenoyl-CoA 2'-pentenyl)- cys monophosphate 2',3'-cyclic didehydrolycopene -glycerol 3- thr a dodecanoyl-[acp] a palmitoyl-[acp] Mg 2+ RS07870 Mg 2+ L-aspartyl-4-phosphate O-phospho- CTZ40_RS29640 CTZ40_RS34310 CTZ40_RS11720 a tRNA Lys 37-C56:2-[acp] formyltetrahydrofolate [sulfur carrier] multifunctional 2',3'- 9-enoyl-[acp] 1-(5-phospho- CTZ40_RS14470 CTZ40_RS30740 CTZ40_RS34595 lysine--tRNA ligase: aldolase: fatty acid--CoA beta-ketoacyl- beta-ketoacyl- 3-phosphate 3-phosphate glycerophosphodiester crotonase/enoyl- cyclopentane-1- cysteine monophosphate 3-oxoacyl-[acyl- carotenoid phosphate bifunctional enoyl-ACP enoyl-ACP CTZ40_RS17065 L-homoserine CTZ40_RS34310 [+ 3 isozymes] SAM [+ 2 isozymes] 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- bifunctional multifunctional 2',3'- 1-acyl-sn-glycerol- threonine β-D-ribosyl)-ATP (S)-2-acetolactate threonine/serine dihydropyrimidinase: gly succinate acetyl-CoA triosephosphate ligase family protein: phosphodiesterase: CoA hydratase (3-oxohexanoyl) cyclic-nucleotide 2'- oxygenase: salicylyl-CoA gln ala CTZ40_RS21475 an L-lysyl- CTZ40_RS06015 ACP synthase II: ACP synthase 3-phosphate 3-phosphate folylpolyglutamate desulfurase: cyclic-nucleotide 2'- carrier-protein] 3-phosphate ammonia-lyase: reductase reductase aspartate- bifunctional threonine hydA anthranilate PRPP isomerase: Amino Acid Degradation acetyl-CoA C- phosphodiesterase/ phosphoribosyl- dehydratase: SAM Lys CTZ40_RS22880 CTZ40_RS33630 II: fabF acyltransferase: acyltransferase: CTZ40_RS10830 family protein: -CoA CTZ40_RS31425 reductase: fabG CTZ40_RS16620 5-hydroxylase/ FabI: fabI FabI: fabI ketol-acid glutamate N- [tRNA ] class II fructose- synthase/ acyltransferase: phosphodiesterase/ acyltransferase: CTZ40_RS14470 2+ 2+ CTZ40_RS37865 semialdehyde synthase: CTZ40_RS05195 [+ 11 isozymes] CTZ40_RS35330 3-oxo-2-(cis- 5'-nucleotidase/ oxidoreductase: Mg RS13665 Mg ATP reductoisomerase: glutamate lys bisphosphate beta-ketoacyl- beta-ketoacyl- CTZ40_RS06430 CTZ40_RS06430 [+ 6 isozymes] dihydrofolate CTZ40_RS08675 [+ 2 isozymes] 5'-nucleotidase/ 3-oxoacyl-ACP carotenoid CTZ40_RS11245 enoyl-ACP enoyl-ACP dehydrogenase: acetyltransferase/ CTZ40_RS12555 3-ureidopropanoate L-asparagine biosynthesis III (tRNA-dependent) glyoxylate triose-phosphate 3'-nucleotidase: threonine/serine CTZ40_RS08930 diphosphatase: (2Z)-2-aminobut- anthranilate synthase: gltB isocitrate lyase/ malate synthase A: aldolase: fbaA L-valine degradation I ACP synthase ACP synthase II: [+ 7 isozymes] [+ 7 isozymes] sn-glycerol [+ 5 isozymes] 2'-pentenyl)- a sulfurated 3'-nucleotidase: reductase: oxygenase: reductase reductase ilvC CTZ40_RS18060 amino-acid L-ornithine degradation II (Stickland reaction) L-isoleucine degradation I L-threonine degradation I L-leucine degradation I L-arginine degradation V L-glutamate AMP diphosphate 18-hydroxyoleoyl-CoA 1-cis-vaccenoyl- ser synthase: (3S,6Z,9Z,12Z,15Z,18Z,21Z)-3- acetyl-CoA ala CTZ40_RS30965 a 2-acyl-1-alkyl-[+ 7 isozymes] dehydratase: CTZ40_RS34495 2-enoate threonine phosphoribosyltransferase: trpD CTZ40_RS30835 phosphoenolpyruvate CTZ40_RS02320 isomerase: II: fabF CTZ40_RS33630 dipalmitoyl 3-phosphate cyclopentane- [sulfur carrier] CTZ40_RS28785 CTZ40_RS19215 gentisyl-CoA FabI: fabI FabI: fabI (2R)-2,3- acetyltransferase SAH (arginine deiminase pathway) degradation VI 2-palmitoleoyl- acyl-carrier protein CTZ40_RS27005 hydroxytetracosahexaenoyl-CoA CTZ40_RS30965 sn-glycerol CTZ40_RS37865 β [+ 2 isozymes] synthase: L-serine biosynthesis I mutase family protein: CTZ40_RS31320 a cis,cis-delta21,39- an (11Z)-3-oxo- acyl-carrier protein phosphatidate a (6S)-5- 1-butanoyl-CoA 3'-cmp a cis-delta9-3- apo-4'-lycopenal a (2E)-dodec- a (2E)-hexadec- Mg 2+ RS05940 Mg 2+ 1-(5-phospho- - dihydroxy-3- ArgJ: argJ anthranilate asp malate synthase A: val (to pyruvate) acyl-carrier protein acyl-carrier protein sn-glycerol- 3'-GMP 3-phosphate 2-oxobutanoate CTZ40_RS16110 glu 3-oxo-C58:2-[acp] icos-11-enoyl-[acp] formyltetrahydrofolate hydroxyC28:1-[acp] 2-enoyl-[acp] 2-enoyl-[acp] D-ribosyl)-AMP methylbutanoate L-aspartate 4- SAH phosphoribosyltransferase: trpD histidine-- CTZ40_RS15130 CTZ40_RS07700 L-ornithine ile thr leu his arg 3-phosphate dihydroxy-acid semialdehyde N-acetyl-L- β 3-phospho-D-glycerate [+ 4 isozymes] D-glyceraldehyde phosphoribosyl- thr -alanine tRNA ligase: branched-chain branched-chain threonine branched-chain glu dehydratase: 2-iminobutanoate glutamate phosphoglycerate 3-phosphate a metal a metal AMP 4-hydroxy- CTZ40_RS34135 an L-histidyl- amino acid amino acid ammonia-lyase: amino acid an [amino group carrier protein]- an N-terminal- uridine 2'3'-cyclic ilvD adenosylhomocysteinase: N-(5-phosphoribosyl)-anthranilate dehydrogenase: ornithine- amino acid arginine deiminase: a peptidoglycan L-alanyl-γ-D-glutamyl-L- 1-palmitoyl- 1-arachidinoyl- 1-palmitoyl- a (2E,5Z)- cyclohydrolase: tetrahydrodipicolinate acetylglutamate S-ribosyl-L- His aminotransferase: CTZ40_RS14470 aminotransferase: 7-hydroxylaurate a cis,cis-delta17,35- a carboxylic ester (S)-4-hydroxymandelate NADH menadione H + a ribonucleoside a cis,cis-delta9,27-3- cation cation gln an L-aspartyl- [tRNA ] glyceraldehyde- aminotransferase: -oxo-acid racemase: CTZ40_RS08950 a malonyl-[acp] dimer (E. faeciums) sn-glycerol a myristoyl-[acp] C-terminal-γ-(L-glutamate 5- L-methionyl-L- monophosphate sn-glycerol sn-glycerol L-threonine 3- ser tetradeca-2,5- RS16085 hisI 3-methyl-2- synthase: dapA CTZ40_RS25015 homocysteine CTZ40_RS11530 a tRNA His D-threo-isocitrate (S)-malate CTZ40_RS11485 CTZ40_RS11485 (2S, 3S)-3- C54:2-[acp] lysyl-D-alanyl-D-alanine 3'-phosphate hydroxyC46:2-[acp] IMP kinase: argB bifunctional 1-(5- Asn CTZ40_RS11485 (S)-3-methyl-2- threonine/serine fatty acid--CoA D-alanyl-D-alanine semialdehyde-2-yl)-L-glutamate carboxylesterase/ seryl-[protein] multifunctional 2',3'- O-phosphate [tRNA ] 3-phosphate transaminase: CTZ40_RS34785 4-methyl-2- beta-ketoacyl- D-alanyl-D-alanine 3-phosphate 1-acyl-sn-glycerol- N-acetyl-gamma- mandelate NADH-quinone type I methionyl multifunctional 2',3'- 3-oxoacyl-[acyl- 3-phosphate 3-phosphate dienoyl-[acp]enoyl-ACP ala ala 1-(5-phospho-β-D-ribosyl)- oxobutanoate 4-hydroxy- phosphoribosyl)-5-((5- 3-phosphooxypyruvate dehydratase: methylaspartate 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- threonine- threonine/serine Asp-tRNA(Asn) dehydrogenase: 3-methyl-2- rocD oxopentanoate oxopentanoate L-citrulline ligase family protein: carboxypeptidase/ carboxypeptidase/ lipase family protein: racemase/muconate oxidoreductase cyclic-nucleotide 2'- bifunctional reductase 5-[(5-phosphoribosylamino) N-acetylglutamyl- ser Asp-tRNA(Asn) malate dehydrogenase: amino-acid ACP synthase II: 3-phosphate glutamyl-phosphate aminopeptidase: cyclic-nucleotide 2'- carrier-protein] 3-phosphate 3-phosphate dehydratase: a metal tetrahydrodipicolinate phosphoribosylamino) /Glu-tRNA(Gln) 3-phosphoserine/ CTZ40_RS04135 CTZ40_RS37865 CTZ40_RS22880 D-alanyl-D-alanine- CTZ40_RS11955 lactonizing protein: phosphodiesterase/ metallophosphatase/ phosphate a metal 2-oxobutanoate phosphate L-homocysteine oxobutanoate racemase: (2Z)-2-aminobut- CTZ40_RS33630 D-alanyl-D-alanine- acyltransferase: reductase: subunit D: map phosphodiesterase/ reductase: fabG acyltransferase: acyltransferase: FabI: fabI RS25005 methylideneamino]imidazole- 2-isopropylmalate branched-chain synthase: dapA methylideneamino)imidazole- /Glu-tRNA(Gln) CTZ40_RS15280 endopeptidase: dacB 5'-nucleotidase/ 5'-nucleotidase: decarboxylase: CTZ40_RS37865 cation cation amidotransferase: phosphohydroxythreonine aconitate hydratase 2-enoate [+ 11 isozymes] endopeptidase: dacB carboxylesterase/ CTZ40_RS33120 CTZ40_RS17145 5'-nucleotidase/ 4-carboxamide synthase: amino acid (2S,4S)-4- amidotransferase: NAD-dependent L-glutamate-5- CTZ40_RS11065 beta-ketoacyl- CTZ40_RS06430 an [amino group carrierCTZ40_RS33705 protein]- [+ 2 isozymes] 3-oxoacyl-ACP CTZ40_RS06430 CTZ40_RS06430 (R)-1-amino-CTZ40_RS31670 L-serine enoyl-ACP acetolactate N-acetyl-gamma- 4- carboxamide isomerase/ gatB gatA gatC transaminase: serC glycine-- AcnA: acnA ornithine penicillin-binding lipase family protein: [+ 2 isozymes] [+ 2 isozymes] an N-terminal 3'-nucleotidase: CTZ40_RS33805 L-homocysteine gatB gatA gatC gly 13-DPG semialdehyde ACP synthase penicillin-binding [+ 7 isozymes] C-terminal-γ-(5-phospho- met 3'-nucleotidase: reductase: [+ 7 isozymes] [+ 7 isozymes] reductase bifunctional 1-(5- CTZ40_RS09620 aminotransferase: synthase: ilvN hydroxy-2,3,4,5- glutamyl-phosphate L-arginine biosynthesis II (acetyl cycle) cystathionine phosphoribosylanthranilate malic enzyme: AMP diphosphate 7-hydroxylauroyl-CoA 1-palmitoyl- CTZ40_RS30965 a 1-arachidonoyl- a 1-palmitoyl-2- [+ 2 isozymes] 2-propanol O ammonia-lyase: [+ 12 isozymes] phosphoserine tRNA ligase: 2-methylbutanoyl-CoA isovaleryl-CoA carbamoyltransferase: mesaconate protein 2: mrdA protein 2: mrdA CTZ40_RS37930 (R)-4-hydroxymandelate menadiol NAD + L-seryl-[protein] CTZ40_RS30965 phosphoribosyl)-5-((5- 2-isopropylmalate CTZ40_RS11485 tetrahydrodipicolinate reductase: isomerase PriA: priA a 4-phosphooxy- CTZ40_RS26260 II: fabF a peptidoglycan tetramer acyl-carrier protein 2-myristoyl L-glutamyl)-L-glutamate CTZ40_RS28785 2-acyl-sn-glycerol acyl-sn-glycerol -2-phosphate CTZ40_RS11840 FabI: fabI a metal a metal CTZ40_RS11545 beta-synthase: cystathionine transaminase: serC CTZ40_RS27540 isobutanoyl-CoA D-ornithine argF a cis,cis-delta19,37- L-alanyl-γ-D-glutamyl- 3'-UMP a cis,cis-delta9,27- inosine a (5Z)-tetradec- RS20310 L-aspartyl- Gly phosphatidate a carboxylate an alcohol a ribonucleoside 3-phosphate cation cation phosphoribosylamino) synthase: leuA (S)-2-aceto-2- 4-hydroxy- CTZ40_RS33705 N-acetylglutamyl- CTZ40_RS24620 1-(2-carboxyphenylamino)-1- ammonium a glycyl-[tRNA ] phosphoglycerate isovaleryl-CoA acyl-carrier protein D-ala with a D,D cross-link D-ala 3-phosphate pyruvate N-acetyl-L- beta-synthase: [tRNA Asn ] cis-aconitate oxaloacetate 2-iminobutanoate 3-oxo-C56:2-[acp] L-lysyl-D-alanine 3-oxo-C46:2-[acp] 5-enoyl-[acp] methylideneamino)imidazole- tetrahydrodipicolinate Gly kinase: dehydrogenase: (Enterococcus faecium) hydroxybutanoate amino-acid N- phosphate deoxy-D-ribulose 5-phosphate CTZ40_RS24620 O-phospho-L-serine a tRNA carbamoyl 4- carboxamide isomerase/ (2S)-2- val reductase: glutamate 5- CTZ40_RS31315 (S)-1-pyrroline- CTZ40_RS26175 L-ornithine ketol-acid acetyltransferase: indole-3-glycerol phosphate Asp-tRNA(Asn) aconitate hydratase (E)-2- phosphate phosphoribosylanthranilate isopropylmalate CTZ40_RS10440 semialdehyde L-cystathionine 5-carboxylate a metal a metal reductoisomerase: synthase TrpC: trpC L-cystathionine 3-methylcrotonyl- (S)-citramalate a long-chain 1-cis-vaccenoyl- sn-glycero-3- an N-terminal- β 1-cis-vaccenoyl- 1-myristoyl- 3S-(4- RS05755 isomerase PriA: priA acetylornithine CTZ40_RS17065 /Glu-tRNA(Gln) phosphoserine AcnA: acnA 3-phospho- methylcrotonoyl-CoA α a cis,cis-delta15,33- a cis,cis-delta7,25- a cis- methyl -D-glucoside a cis,cis-delta7,25-3- cation cation 3-isopropylmalate (S)-2,3,4,5- methylacrylyl-CoA pyrroline-5- (2R,4S)-2, 4- CoA glutamine- an -D-galactoside sn-glycerol- a purine succinyl-CoA a 3-oxo acid a 2-oxo L-methionyl-L- a RNA-DNA hybrid hydroxyphenyl) 5-MTR-1-P ilvC hydrogencarbonate transaminase: indole-3-glycerol phosphate amidotransferase: phosphatase SerB: serB citrate synthase/ citramalate a malonyl-[acp] a malonyl-[acp] 2,3,4-saturated phospho-N- L-ornithine 6-phosphate sn-glycerol- sn-glycerol cys a butanoyl-[acp] tetrahydrodipicolinate bifunctional N-acetyl-gamma- D-glycerate carboxylate diaminopentanoate crotonase/enoyl- hydrolyzing alpha-glucosidase/ C52:2-[acp] C44:2-[acp] vaccenoyl-[acp] ribonucleoside arsenate carboxylate hydroxyC44:2-[acp] phosphoribulosylformimino- dehydratase: synthase TrpC: trpC cystathionine gatB gatA gatC methylcitrate synthase: 2-oxobutanoate methylcrotonoyl- beta-ketoacyl- beta-ketoacyl- fatty acid 1-acyl-sn-glycerol-3-phosphate (arachidonoyl) acyl CoA:acetate/ alanyl-[protein]type I methionyl bifunctional 6-phospho-beta- 3-phosphate 3-phosphate -3-hydroxy- lanthionine S-methyl-5- enoyl-ACP (R)-2,3-dihydroxy- CTZ40_RS33720 glutamate N- glutamyl-phosphate cystathionine methionine-- crotonase/enoyl- reductase: CoA hydratase carbamoyl- synthase: fatty acid-- purine-nucleoside ornithine- 3-oxoacyl-[acyl- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- AICAR-phosphate leuC leuD 2,3,4,5- glutamine- gamma-synthase: met CoA carboxylase: alpha-galactosidase: ACP synthase II: 3-phosphate ethanolamineglycerophosphoryl 3-ketoacid CoA aminopeptidase: RNase H/acid glucosidase: propanoyl-CoA thioribose-1- reductase 3-methylpentanoate acetyltransferase/ reductase: gamma-lyase: ser tRNA ligase: CTZ40_RS09925 phosphoglyceromutase: family protein: CTZ40_RS11460 ACP synthase II: CoA ligase phosphorylase: -oxo-acid carrier-protein] 3-phosphate 3-phosphate crotonase/enoyl- synthetase: a metal a metal tetrahydropyridine- hydrolyzing N-acetyl-L- CTZ40_RS14490 acetyl-CoA CoA hydratase proC CTZ40_RS26190 phosphate CTZ40_RS33550 phosphatase: CTZ40_RS26665 RS09605 3-isopropylmalate dihydroxy-acid amino-acid CTZ40_RS19355 (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate an L-asparaginyl- CTZ40_RS20250 [+ 3 isozymes] CTZ40_RS05300 CTZ40_RS33630 CTZ40_RS33630 family protein: acyltransferase: diester transferase transaminase: map reductase: fabG acyltransferase: acyltransferase: CoA hydratase CTZ40_RS00770 phosphate FabI: fabI cation cation 2,6-dicarboxylate N- carbamoyl- ornithine acetylglutamate CTZ40_RS33705 L-isoleucine an L-methionyl- CTZ40_RS16340 family protein: hypothetical synthase: L-histidine degradation I CTZ40_RS14675 imidazole dehydratase: Asn S-adenosyl-L-methionine cycle II 3-methylglutaconyl- pyruvate acetate alpha-galactosidase: CTZ40_RS06430 phosphodiesterase: subunit beta: CTZ40_RS28810 6-phospho-beta- isomerase: dehydratase: acetyltransferase cys [tRNA ] [initiator tRNA Met ] citrate CTZ40_RS05300 [+ 5 isozymes] carA carB beta-ketoacyl- beta-ketoacyl- CTZ40_RS22880 rocD [+ 2 isozymes] 3-oxoacyl-ACP CTZ40_RS06430 CTZ40_RS06430 family protein: [+ 2 isozymes] enoyl-ACP leuD leuC succinyltransferase: phosphate kinase: argB biosynthesis IV protein: (2R)-2-amino-4- CTZ40_RS34715 ribose-1-arsenate a purine base CTZ40_RS08120 L-glutamate-5- a proteinogenic an N-terminal L- glycerol ilvD ArgJ: argJ N-acetyl-L- tryptophan synthase: initiator tRNA Met CoA ACP synthase ACP synthase [+ 7 isozymes] CTZ40_RS34580 [+ 2 isozymes] glucosidase: reductase: [+ 7 isozymes] CTZ40_RS05300 lanthionine 5-(methylsulfanyl)mtnA reductase dapD synthase: N-acetyl-L- (2Z)-2-aminobut- 2-phospho- [+ 5 isozymes] CTZ40_RS17520 oxopentanoate (2S,3S)-3-hydroxy-2- propanoyl-CoA a non galactosylated [+ 11 isozymes] 1,2-dicis- a 2,3,4-saturated met 1,2-dicis-[+ 7 isozymes] 1,2-dimyristoyl- phosphate glu glutamate 5- cys trpB CTZ40_RS30775 carbamate his α a long-chain [+ 6 isozymes] succinate semialdehyde amino acid alanyl-[protein] a nucleoside 5'- CTZ40_RS27385 a metal a metal 2-isopropylmaleate (S)-3-methyl-2- 2-enoate propanoate methylbutanoyl-CoA -D-galactopyranose II: fabF II: fabF acyl-carrier protein vaccenoyl- sn-glycerol DNA β CTZ40_RS28785 vaccenoyl- sn-glycerol (E)-4- [+ 5 isozymes] -ribulose 1- FabI: fabI RS27470 N-succinyl-2-amino- carA carB glutamate met D-glycerate (S)-3-hydroxy- galactose acceptor a cis,cis-delta9,27- AMP diphosphate 2,3,4-saturated anandamide 3-oxoacyl-CoA monophosphate -D-glucose a cis,cis-delta7,25- a (2E)-but- cation synthase: gln semialdehyde phosphate histidine acyl-carrier protein a cis,cis-delta17,35- acyl-carrier protein 3-phosphate MeOH phosphatidate 3-phosphate phosphate cation oxopentanoate acetylornithine indole ser methionine isobutanoyl-CoA pro fatty acyl CoA phosphatidate 6-phosphate coumaroyl-CoA hisH hisF 3-isopropylmalate 6-ketopimelate carbamoyl phosphopyruvate propionyltransferase: ammonia- 3-oxo-C54:2-[acp] 3-oxo-C46:2-[acp] 3-oxo-C44:2-[acp] 2-enoyl-[acp] branched-chain L-ornithine transaminase: adenosyltransferase: 3-hydroxyisobutyryl- dehydratase: phosphate hydratase: CTZ40_RS12165 HMG-CoA lyase: hutH D-erythro-1- amino acid succinyldiaminopimelate glutamine- CTZ40_RS33720 propanoyl-CoA L-tyrosine 5-methyltetrahydropteroyltriglutamate- CTZ40_RS34310 CoA hydrolase: proline racemase: CTZ40_RS01275 acetyl-CoA urocanate 2+ 2+ AICAR leuC leuD aminotransferase: transaminase: dapC hydrolyzingbifunctional 2-iminobutanoate tryptophan synthase: biosynthesis I - homocysteine S- CTZ40_RS24705 propanoyl Zn RS31680 Zn (imidazol-4- L-proline CTZ40_RS08875 2-methylacetoacetyl-CoA hydroxymethylglutaryl- CO a ring-opened 7- an N-terminal- (11Z)-(S)-3- a [protein]- 3-isopropylmalate ornithine carbamoyl-glutamate N- L-proline biosynthesis trpB CTZ40_RS30775 2-oxoacid:ferredoxin phosphopyruvate phosphate 2 PRPP a cis,cis-delta5,23- demethylmenaquinol-4 an N-terminal-L-methionyl- O-ureido-L- 1-cis-vaccenoyl-sn- a cis,cis-delta5,23-3- a cellodextrin yl)-glycerol CTZ40_RS11485 N-succinyl-L,L-2,6- methyltransferase: metE [+ 2 isozymes] CoA lyase: urocanate 5-amino-4-imidazolecarboxyamide a malonyl-[acp] pentadecanoate phytenate succinate succinyl-CoA acetoacetate L-methionyl-L- asp hydroxyhexadec- DHAP phosphoenol a myristoyl-[acp] carbamoyltransferase: I (from L-glutamate) biosynthesis III Fatty Acid and Lipid Biosynthesis hydratase: (S)-3-hydroxy- methylguanine in DNA L-cysteinyl-[protein] glycerol-3-phosphate L-histidine dGDP 3-phosphate dehydratase: diaminopimelate phosphateacetyltransferase/ oxidoreductase chorismate [+ 2 isozymes] acetyl-CoA C- hydratase: hypothetical protein: bifunctional DNA- C42:2-[acp] fatty acid-- long-chain fatty ADP-forming demethylmenaquinone acyl CoA:acetate/ type I methionyl valyl-[protein] homoserine hydroxyC42:2-[acp] 11-enoyl-CoA NAD(P)-dependent 1, 4-beta histidine kinase: pyruvate argF (from L-ornithine) isobutanoate acetate kinase: CTZ40_RS26180 beta-ketoacyl- type I methionyl argininosuccinate 1-acyl-sn-glycerol- 3-oxoacyl-[acyl- enoyl-ACP leuD leuC synthase: amino-acid subunit beta: chorismate mutase: CTZ40_RS24510 D-proline acyltransferase: CTZ40_RS24715 crotonase/enoyl- cellobiohydrolase: pyruvate 2+ 2+ imidazoleglycerol- ile succinyl- CTZ40_RS12170 CTZ40_RS30705 formamidopyrimidine ACP synthase II: CoA ligase acid--CoA ligase: succinate--CoA methyltransferase: 3-ketoacid CoA aminopeptidase: carrier-protein] glycerol-3- CTZ40_RS20950 reductase Zn RS27535 Zn carA carBacetyltransferase glu trp CTZ40_RS21975 CTZ40_RS06595 palmitate biosynthesis II 3-hydroxyisobutyrate CTZ40_RS08675 aminopeptidase: synthase: 3-phosphate CoA hydratase phosphate (2R,3S)-3- L-ornithine L-homocysteine SAM acetoacetate 4-imidazolone- adenine glycosylase/ family protein: CTZ40_RS18745 ligase: sucD sucC CTZ40_RS21810 transferase map phosphate CTZ40_RS25890 histidine kinase: kinase: pyk diaminopimelate ammonium (bacteria and plant cytoplasm) palmitoleate superpathway of fatty acid phosphoenol dehydrogenase: CTZ40_RS33630 map CTZ40_RS33785 acyltransferase: reductase: fabG FabI: fabI isopropylmalate ArgJ: argJ N-acetyl-L- glutamate 5-kinase: ornithine- [+ 3 isozymes] propanoate DNA-(apurinic CTZ40_RS22880 family protein: 1, 4-beta pyruvate dehydratase desuccinylase: asp L-citrulline carbamoyl L-ornithine 2-oxobutanoate biosynthesis I (from biosynthesis initiation (E. coli) pyruvate mmsB L-proline degradation propanoyl-CoA acetyl-CoA 5-propanoate phosphoribosyltransferase: beta-ketoacyl- [+ 11 isozymes] demethylmenaquinone subunit beta: [+ 2 isozymes] [+ 2 isozymes] CTZ40_RS06430 3-oxoacyl-ACP dehydrogenase: a [protein]-CTZ40_RS35595 enoyl-ACP ornithine prephenate L-homoserine glycine cleavage phosphate ADP succinyl-CoA argininosuccinate CTZ40_RS35330 kinase: pyk HisB: hisB 3-isopropylmalate CTZ40_RS13740 phosphate CTZ40_RS27105 -oxo-acid (5Z)-dodec-5-enoate) L-serine degradation imidazolonepropionase: CTZ40_RS34110 or apyrimidinic [+ 11 isozymes] methyltransferase: CTZ40_RS08120 an N-terminal L- an N-terminal CTZ40_RS11240 cellobiohydrolase: thr thr γ-L-glutamyl (S)-methylmalonate- ACP synthase met met synthase: argG 1-cis-vaccenoyl-[+ 7 isozymes] reductase: [+ 5 isozymes] N-phospho- reductase RS17275 3-(imidazol-4- dehydrogenase: acetolactate transaminase: prephenate biosynthesis an acetoacetyl-[acp] acetyl-CoA TCA cycle TCA cycle IV (2-oxoglutarate decarboxylase) pyruvate site) lyase: mutM diphosphate AMP phytenoyl-CoA CTZ40_RS07665 cysteinyl-[protein] L-valyl-[protein] (2E,11Z)-hexadec- sn-glycerol CTZ40_RS26115 dGTP pyruvate serine serine 5-phosphate a (5Z)-dodec- semialdehyde CTZ40_RS24730 a [glycine-cleavage AICAR 2,6-diamino-4- II: fabF pentadecanoyl- acetoacetyl-CoA succinate 2-palmitoleoyl-sn- CTZ40_RS28785 L-histidine FabI: fabI yl)-2-oxopropyl CTZ40_RS11490 superpathway of L-serine L,L-diaminopimelate L-ornithine synthase: ilvN rocD phosphoenolpyruvate 5-aminopentanoate pro AMP diphosphate canavaninosuccinate 3-phosphate argininosuccinate L-glutamate-5- dehydrogenase: 5-enoyl-[acp] kinase: pyk complex H protein] an apurinic site a cis,cis-delta7,25- CoA menaquinol-4 a cis,cis-delta5,23- 2,11-dienoyl-CoA β-D-cellobiose a (2E)-tetradec- phosphate and glycine biosynthesis I biosynthesis II glutamate-5- 3-oxoacyl-[acyl- beta-ketoacyl- synthase: L-threonine glycine hydroxy-5-(N-methyl) acyl-carrier protein glycerol-3-phosphate (2S)-2-isopropyl- synthase: CTZ40_RS11545 CTZ40_RS06470 asp pyruvate proline ser N-formimino- 6 within DNA 3-oxo-C44:2-[acp] 3-oxo-C42:2-[acp] 2-enoyl-[acp] semialdehyde carrier-protein] acetyl-CoA carboxylase (S)-malate CTZ40_RS38960 methylmalonate- degradation III (to N -lipoyl-L-lysine formamidopyrimidine histidinol- diaminopimelate CTZ40_RS33785 semialdehyde L-arginine adenosylhomocysteinase: ACP synthase dehydrogenase: L-arginine degradation X (arginine threonine/serine L-glutamate cleavage 3-oxosuccinate 2-oxoglutarate (S)-2-aceto-2- prephenate aspartate kinase: reductase: fabG kinase: pyk semialdehyde methylglyoxal) glycine arsenite RS02155 arsenite phosphate 3-phospho-D-glycerate epimerase: dehydrogenase: degradation I CTZ40_RS25015 II: fabF carboxyltransferase CTZ40_RS11510 monooxygenase pathway) dehydratase: system argininosuccinate ornithine glutamate hydroxybutanoate dehydrogenase: CTZ40_RS18065 dehydrogenase: (S)-1-pyrroline- cleavage transaminase: phosphoglycerate CTZ40_RS10150 CTZ40_RS27115 (arginase pathway) 3-oxoacyl-ACP beta-ketoacyl- subunit: CTZ40_RS15775 protein 1-stearoyl- α an N-terminal- synthase: argG carbamoyltransferase: dehydrogenase: 2-aceto-2-hydroxy- CTZ40_RS32255 L-aspartyl- SAH malate dehydrogenase: (S)-3-amino-2- 5-carboxylate thr CTZ40_RS37865 ManNAc-GlcNAc- (2-hydroxyphenyl)methyl 1-hydroxy- α,ω-9Z- an NDP- - 3-phospho- an N-terminal-L-methionyl- (2E)-tetradec- (2E,7Z)- 1-palmitoyl- an (2E,11Z) hisC dehydrogenase: reductase: an acetyl-[acp] pyruvate CTZ40_RS08865 system GcvH: gcvH CDP-glycerol a cis,cis-delta3,21- an aryl dialkyl an N-acylated- L-methionyl- NaMN a cis,cis-delta7,19-3- 3'-UMP a nucleoside argF L-glutamate-5- (S)-1-pyrroline- 3-(4- ACP synthase II: CTZ40_RS15280 methylpropanoate arg L-threonine L-serine PP-undecaprenol 6-oxocyclohex-2-ene-1-carboxylate a malonyl-[acp] an oleoyl-[acp] sn-glycerol octadecenedioate D-glucose D-glycerate L-threonyl-[protein] 2-enoyl-CoA tetradecenoyl-CoA sn-glycerol phosphoenol -icosa-2,11- CTZ40_RS11530 meso-diaminopimelate CTZ40_RS06950 arg butanoate 4-phosphate CTZ40_RS28785 protein C40:2-[acp] phosphate D-amino acid hydroxyC38:2-[acp] diphosphate dADP a reduced histidinol- 4-methyl-2- L-arginino- semialdehyde hydroxyphenyl) CTZ40_RS33630 malonyl-CoA dehydrogenase: ammonia-lyase: [+ 2 isozymes] bifunctional glycosyltransferase carboxylesterase/ beta-ketoacyl- 3-phosphate long-chain fatty glucosyl-3- D-aminoacylase: type I methionyl glycyl-[protein] bifunctional crotonase/enoyl- 3-oxoacyl-[acyl- crotonase/enoyl- multifunctional 2',3'- 3-phosphate nucleoside- pyruvate dienoyl-[acp]enoyl-ACP 3-phosphooxypyruvate isomeroreductase: 5-carboxylate a (7Z)-3-oxotetradec- NAD-dependent malic GcvH: gcvH 1-acyl-sn-glycerol- aryldialkylphosphatase: type I methionyl 1-acyl-sn-glycerol- H O c-type oxopentanoate glu fumarate hydratase: glu lipase family protein: acid--CoA ligase: phosphoglycerate CoA hydratase cyclic-nucleotide 2'- pyruvate 2 phosphate succinate ilvC pyruvate aspartate- a (3R)-3- hydrogencarbonate CTZ40_RS31230 CTZ40_RS11840 a [glycine-cleavage family 2 protein/CDP- ACP synthase II: 3-phosphate CTZ40_RS11055 CTZ40_RS14380 aminopeptidase: aminopeptidase: metallophosphatase/ carrier-protein] CoA hydratase diphosphate reductase Orn/DAP/Arg pyrroline-5- 7-enoyl-[acp] enzyme: CTZ40_RS26260 L-2-amino-3- 2-aminoprop- [+ 3 isozymes]a [glycine-cleavage 3-phosphate kinase: pyk RS32335 cytochrome transaminase: branched-chain semialdehyde hydroxybutanoyl-[acp] ACP S-malonyltransferase: CTZ40_RS14090 6 glycerol:glycerophosphate CTZ40_RS11955 CTZ40_RS33630 CTZ40_RS18745 synthase: map 5'-nucleotidase: family protein: reductase: fabG family protein: phosphodiesterase/ kinase: FabI: fabI an oxidized 3-phosphoserine/ decarboxylase 2: argininosuccinate (R)-2,3-dihydroxy- carboxylate L-cysteine L-glutamate-5- 4-guanidinobutyramide oxobutanoate 2-enoate 6 complex H protein] N - acyltransferase: phosphotriesterase: D-aminoacylase: map acyltransferase: CTZ40_RS30645 amino acid glutamate 5-kinase: L-ornithine dehydrogenase: 3-oxoacyl-ACP CTZ40_RS17945 complex H protein] N glycerophosphotransferase: CTZ40_RS16115 CTZ40_RS16415 CTZ40_RS35330 CTZ40_RS35330 5'-nucleotidase/ pyruvate O c-type class II fumarate hydratase: malate synthase A: carboxylesterase/ CTZ40_RS06430 [+ 11 isozymes] CTZ40_RS22940 [+ 2 isozymes] CTZ40_RS27015 2 phosphohydroxythreonine CTZ40_RS24685 lyase: argH 3-methylpentanoate reductase: fumarate oxaloacetate degradation II semialdehyde -dihydrolipoyl-L-lysine aminomethyldihydrolipoyl- beta-ketoacyl- CTZ40_RS34790 2-O-(α-D- [+ 2 isozymes] 3-oxoacyl-ACP CTZ40_RS06430 enoyl-ACP aminotransferase: CTZ40_RS27105 CTZ40_RS18060 reductase: ACP S-malonyltransferase: CTZ40_RS14095 CTZ40_RS02320 amidase: CTZ40_RS25195 lipase family protein: ω-carboxy- a dialkyl an N-terminal L- an N-terminal [+ 2 isozymes] [+ 5 isozymes] [+ 5 isozymes] 3'-nucleotidase: a nucleoside kinase: pyk cytochromea reduced L-histidinol transaminase: serC [+ 3 isozymes] (S)-1-pyrroline- dihydroxy-acid proC L-lysine ACP synthase [+ 71-stearoyl-2- isozymes] a phenol a nucleoside glucopyranosyl) a carboxylate a D-amino acid met met (S)-3- reductase: 1-palmitoyl-[+ 7 isozymes] reductase CTZ40_RS11485 L-citrulline ornithine- S-adenosyl-L-methionine cycle I CTZ40_RS28785 CTZ40_RS28115 L-glutamate Gro-P-ManNAc-GlcNAc- AMP diphosphate (9Z)-octadec- phosphate β-D- (S)-3-hydroxy-(7Z) CTZ40_RS30965 triphosphate dATP pyruvate H O c-type phosphate γ-L-glutamyl 5-carboxylate [+ 2 isozymes] malate synthase A: CTZ40_RS32760 CMP CTZ40_RS37930 II: fabF threonyl-[protein] glycyl-[protein] CTZ40_RS28785 FabI: fabI 2 phosphoserine arg dehydratase: hypothetical tyr cys gamma- L-glutamate PP-undecaprenol 1-hydroxy-6-oxocyclohex- acyl-carrier protein oleoyl-sn-glycerol 9-enoyl-CoA diphosphate -3-phospho- ribosylnicotinate hydroxytetradecanoyl- -tetradecenoyl-CoA 2-myristoyl cytochrome cytochrome -oxo-acid 3-oxoacyl- CTZ40_RS07700 L-arginine [+ 6 isozymes] salicyl alcohol a cis,cis-delta5,23- a cis,cis-delta7,19- uridine an oxidized thiol RS19265 thiol histidinol- transaminase: serC lys 5-phosphate pyrroline-5- ilvD protein: L-aspartate 4- citrate synthase/ cystathionine semialdehyde 2-iminopropanoate degradation I acyl-carrier protein 3-phosphate D-glycerate CoA phosphatidate a gondoyl-[acp] c oxidase leu argininosuccinate transaminase: a (2E)-but-2-enoyl-[acp] [acyl-carrier- a malonyl-[acp] degradation aminoacetone 2-ene-1-carboxylate 3-oxo-C42:2-[acp] 3-oxo-C38:2-[acp] O c-type carboxylate semialdehyde SAM methylcitrate synthase: 2 phosphatase: L-alanine synthase: glutamate-5- rocD (S)-3-methyl-2- CTZ40_RS17520 protein] succinate dehydrogenase, III (arginine gamma-lyase: dehydrogenase: 4-guanidinobutanoate L-glutamine glycine a reduced O-phospho-L-serine reductase: CTZ40_RS09925 cytochrome hisN L-cysteine biosynthesis II CTZ40_RS33785 semialdehyde oxopentanoate homoserine enoyl-ACP reductase: cytochrome b556 decarboxylase/ 2-aminoprop-CTZ40_RS19355 pruA L-glutamine primary-amine glu degradation II cleavage H O c-type proC L-glutamate-5- 2 biosynthesis I dehydrogenase: pro dehydrogenase: reductase 3-oxoacyl-ACP synthasebeta-ketoacyl-ACP synthase subunit: sdhC [+ 3 isozymes] agmatinase pathway) degradation I oxidase: system argininosuccinate semialdehyde branched-chain methionine fabG 2-enoate NAD-glutamate (2E)- DNA combined with a [DNA]-3'- a 5'-phospho- an (R)-2- a carboxy- (25S)-3- N-acetyl-α- a [release factor]- guanosine 2251 (2E,5Z)- 1-palmitoyl- β-D-glucose a supercoiled a (2E,9Z)- RS03890 cytochrome D-ribose RS28045 D-ribose histidinol phosphoserine hypothetical arg glu a [ribosomal protein a cis,cis-delta7,19- + a [ThiI sulfur-carrier a cis,cis-delta5,17-3- 3'-cmp an oxidized pyruvate synthase: argG CTZ40_RS27115 amino acid CTZ40_RS12560 FabI: fabI a (3R,7Z)-3- III: CTZ40_RS12625 II: CTZ40_RS33630 [+ 5 isozymes] CTZ40_RS32870 dehydrogenase: gln protein a sulfurated [sulfur carrier] a malonyl-[acp] exogenous DNA to form NAD cys adenylated-[ThiS cys oxocholest- coenzyme A D-muramoyl- sn-glycerol octadeca-2,9- adenosyltransferase: pyruvate 89 hexadecenoate hydroxyl [DNA] halocarboxylate L-glutamine in 23S rRNA dodecenoyl-CoA 6-phosphate duplex DNA O c-type phosphatase SerB: serB alanine pyridoxal phosphate- protein: L-glutamate [+ 3 isozymes] beta-ketoacyl-ACP succinate citrate GcvH: gcvH S12] L-aspartate C38:2-[acp] protein]-L-cysteine hydroxyC36:2[acp] 2 histidinol ser L-arginino- L-glutamate-5- aminotransferase: CTZ40_RS34310 enoyl-ACP hydroxytetradec- gln CTZ40_RS25155 glutamate long-chain fatty beta-ketoacyl- a recombinational junction NAD- HAD family sulfur-carriercysteine protein] cysteine 4-en-26-oate acyl-CoA L-alanine(1-)N-acetylmuramoyl- peptide chain 23S rRNA 3-oxoacyl-[acyl- crotonase/enoyl- multifunctional 2',3'- 3-phosphate inositol-3- replicative dienoyl-[acp]enoyl-ACP a reduced L-glutamate racemization dependent CTZ40_RS17520 gamma- L-homoserine 4-aminobutanoate methylglyoxal 30S ribosomal Holliday junction 1-acyl-sn-glycerol- cytochrome dehydrogenase: serine semialdehyde CTZ40_RS11485 reductase 7-enoyl-[acp] synthase II: fabF aconitate hydratase Asp-tRNA(Asn) synthase: gltB [+ 2 isozymes] acid--CoA ligase: dependent hydrolase: synthetase: release factor (guanosine(2251) CoA hydratase cyclic-nucleotide 2'- phosphate DNA H O c-type biosynthesis III succinate glutamate protein S12 ACP synthase II: resolvase RuvX: ruvX desulfurase: desulfurase: L-alanine amidase: carrier-protein] 3-phosphate reductase 2 ser aminotransferase: semialdehyde glyoxylate agmatine CTZ40_RS18745 CTZ40_RS11320 phosphodiesterase/ 3+ 3+ hisD acetyltransferase: met SAH FabI: fabI succinate-semialdehyde AcnA: acnA 2-iminopropanoate /Glu-tRNA(Gln) CTZ40_RS30835 CTZ40_RS33630 DNA ligase CTZ40_RS31425 CTZ40_RS31425 CTZ40_RS35260 CTZ40_RS11710 N(5)-glutamine -2'-O)- reductase: fabG family protein: synthase: helicase: FabI: fabI cytochrome Fe RS09375 Fe CTZ40_RS14390 argininosuccinate ornithine- pro dehydrogenase: superpathway of L-asparagine biosynthesis long-chain fatty dehydrogenase: methylthiotransferase crossover junction acyltransferase: RS28525 an oxidized ala CTZ40_RS05570 ile amidotransferase: glu [+ 11 isozymes] LigA: ligA [+ 12 isozymes] [+ 3 isozymes] methyltransferase: methyltransferase CTZ40_RS35330 5'-nucleotidase/ CTZ40_RS19545 dnaB histidinal 2-oxoglutarate serine lyase: argH -oxo-acid pruA an acetoacetyl-[acp] acid activation dehydrogenase (NADP(+) agmatinase: L-phenylalanine degradation I (aerobic) CTZ40_RS06950 RimO: rimO a [ribosomal protein beta-ketoacyl- endodeoxyribonuclease [+ 2 isozymes] a [ThiI sulfur- [+ 2 isozymes] (25S)-3- [+ 5 isozymes] 3-oxoacyl-ACP CTZ40_RS06430 enoyl-ACP O c-type alanine racemase: O-acetyl-L-serine an (S)-2- 2 NADP-specific pyridoxal phosphate- a butanoyl-[acp] ): CTZ40_RS15615 gatB gatA gatC L-glutamate 2-oxoglutarate an unsulfurated a halide anion N-acetyl-D- prmC RlmB: rlmB [+ 5 isozymes] 3'-nucleotidase: [+ 5 isozymes] hydroxymethyltransferase: transaminase: speB 5'-deoxyadenosine met S12]-3-methylsulfanyl- (2E)- ACP synthase resolution of recombinationalRuvC: ruvC a thiocarboxy- carrier protein]-S- ala oxocholest-4- ala 5 2-O- reductase: 1-palmitoyl-2-[+ 7 isozymes] Ins(3)P reductase urea RS32730 cytochromeurea CTZ40_RS19525 dependent 5-methyltetrahydropteroyltriglutamate- a (2E,7Z)-tetradeca- a long-chain L-glutamate [sulfur carrier] AMP diphosphate NMN AMP [DNA] hydroxyarboxylate AMP ala muramate a [release factor]-N (S)-3-hydroxy-(5Z) CTZ40_RS30965 a single histidinol glutamate CTZ40_RS12510 rocD glu asp agmatinase: (6R)-4a-hydroxy- [+ 12 isozymes] degradation IX (via L-aspartate 89 hexadecenoyl-CoA II: fabF junction formation [ThiS-Protein] sulfanyl-L-cysteine en-26-oyl-CoA methylguanosine 2251 CTZ40_RS28785 cis-vaccenoyl FabI: fabI [+ 3 isozymes] aminotransferase: arg - homocysteine S- beta-ketoacyl- 2,7-dienoyl-[acp] fatty acid degradation X -methyl-L-glutamine -dodecenoyl-CoA cytidine stranded DNA chloride RS33940 chloride dehydrogenase: dehydrogenase: cysteine synthase: tetrahydrobiopterin 4a-hydroxytetrahydrobiopterin glu 4-aminobutanoate) a cis,cis-delta9,21- in 23S rRNA a cis,cis-delta5,17- [+ 2 isozymes] D-ala L-glutamate ACP synthase II: long-chain fatty isocitrate lyase/ speB acyl-carrier protein of two intact strands phosphatidate an oleoyl-[acp] hisD CTZ40_RS11685 CTZ40_RS25630 CTZ40_RS35905 L-ornithine methyltransferase: metE enoyl-ACP pyruvate 3-oxo-C40:2-[acp] 3-oxo-C36:2-[acp] biosynthesis II acid--CoA ligase: succinate semialdehyde phosphoenolpyruvate dehydratase: ala glycine biosynthesis II asparagine asparagine [+ 2 isozymes] S-ribosyl-L- CTZ40_RS33630 reductase cis-aconitate putrescine glu L-asparagine glu F0F1 ATP [+ 2 isozymes] gly L-homocysteine CTZ40_RS18745 mutase family protein: CTZ40_RS06770 H + H + cys synthase (glutamine- synthetase B: homocysteine beta-ketoacyl- FabI: fabI biotin-carboxyl carrier L-alanine glutamate degradation I glutamate synthase his glu 2-oxoglutarate [+ 11 isozymes] protein assembly a long-chain multifunctional oxoglutarate CTZ40_RS15130 dehydrogenase: trans,octacis (S)-3- allantoin RS11115 allantoin glutamate a [glycine-cleavage complex hydrolyzing): asnB CTZ40_RS38690 ACP synthase enoyl-ACP degradation IV decarboxylase: (15Z)- GDP-α-D- an (S)-2- a nucleoside long chain 6 gly a [formate C a cis,cis-delta5,17- stachyose a kanamycin acetyl-CoA a cis-2-enoyl-CoA roseoflavin nitrate H protein] N -lipoyl-L-lysine II: fabF acyl-CoA decarboxylase/oxoglutarate [+ 4 isozymes] CTZ40_RS17335 CTZ40_RS06950 SAM a reduced flavodoxin tetracosenoate a malonyl-[acp] -decaprenyl halocarboxylate a ribonucleic acid cys an L-amino acid asn hydroxyhexadecanoyl- dehydrogenase: glycine cleavage system [+ 5 isozymes] [+ 5 isozymes] reductase a [biotin carboxyl- (6R)-L-erythro-5,6,7,8- L-erythro-7,8- asn acetyltransferase]-glycine C36:2-[acp] mannose triphosphate ATP H O polyphosphate dIDP dehydrogenase thiamine 4-aminobutanoate 2-oxoglutarate long-chain fatty phosphate alpha-glucosidase/ HAD family 2 CoA aminoglycoside acetyl-CoA crotonase/enoyl- bifunctional respiratory CTZ40_RS06950 FabI: fabI carrier protein]-L-lysine aconitate hydratase ala asparaginase: pyruvate beta-ketoacyl- polyprenol sigma-70 family cysteine dioxygenase amino-acid racemase: amino acid racemase: crotonase/enoyl- inorganic protein GcvH: gcvH pyrophosphate-binding tetrahydrobiopterin dihydrobiopterin alpha-galactosidase: hydrolase: ATPase: phosphotransferase: riboflavin kinase/ nitrate reductase: nucleoside- a 3-oxohexanoyl-[acp] AcnA: acnA acid--CoA ligase: ACP synthase II: monophosphomannose RNA polymerase type I: CTZ40_RS10235 CTZ40_RS11065 CTZ40_RS34785 carboxylase CoA hydratase polyphosphate glu [+ 2 isozymes] a (7Z)-tetradec- biotin--[acetyl-CoA- subunit/dihydrolipoyllysine- alanine CTZ40_RS16590 formate lyase- CTZ40_RS33550 CTZ40_RS26660 CoA hydratase CTZ40_RS20020 diphosphate a [glycine-cleavage complex H protein] asn asn CTZ40_RS18745 CTZ40_RS33630 CTZ40_RS11320 carboxyltransferase family protein: kinase: FAD synthetase: CTZ40_RS02290 fluoride RS13055 fluoride carboxylase] ligase: activating synthase: sigma factor: cysteine dioxygenase: amino acid racemase: amino-acid racemase: family protein: 6 3-oxoacyl-[acyl- 7-enoyl-[acp] residue succinyltransferase dehydrogenase: ald asp alpha-galactosidase: [+ 2 isozymes] aminoglycoside CTZ40_RS10595 narH narI kinase: N -aminomethyldihydrolipoyl-L-lysine protein: pflA [+ 11 isozymes] beta-ketoacyl- CTZ40_RS01170 [+ 12 isozymes] CTZ40_RS06465 CTZ40_RS24945 CTZ40_RS34785 CTZ40_RS11065 subunit: CTZ40_RS05300 CTZ40_RS08840 Nucleoside and Nucleotide Biosynthesis carrier-protein] CTZ40_RS14575 subunit: CTZ40_RS12825 pyruvate a [formate C an (S)-2- + CTZ40_RS05300 roseoflavin CTZ40_RS27015 beta-ketoacyl- 2-oxoglutarate D-threo-isocitrate a flavodoxin trans,octacis- CTZ40_RS34715 a halide anion H phosphate ADP phosphotransferase: CTZ40_RS15775 [+ 5 isozymes] [+ 2 isozymes] a [biotin carboxyl- met 5'-deoxyadenosine acetyltransferase]- (15Z)- ACP synthase [+ 4 isozymes] 3-sulfino-L-alanine a D-amino acid D-asparagine [+ 5 isozymes] [+ 2 isozymes] reductase: fabG ACP synthase II: semiquinone AMP diphosphate GDP decaprenylphospho- α-D-galactopyranose raffinose hydroxyarboxylate (2E)- CTZ40_RS23720 a (3R)-3- long chain 5'-phosphate dITP carrier protein]-N glycin -2-yl radical tetracosenoyl-CoA II: fabF a ribonucleic acid malonyl-CoA nitrite superpathway of purine nucleotides de novo biosynthesis I 3-oxoacyl-ACP CTZ40_RS33630 β-D-mannose a kanamycin hydroxyacyl-CoA polyphosphate Peptide RS05375 Peptide superpathway of guanosine pyrimidine deoxyribonucleotides de novo biosynthesis III 6 -biotinyl-L-lysine a cis,cis-delta7,19- hexadecenoyl-CoA superpathway of pyrimidine adenine and adenosine salvage III xanthine and reductase: acyl-carrier protein 3'-phosphate nucleotides de novo biosynthesis I beta-ketoacyl- 3-oxo-C38:2-[acp] ribonucleotides de novo biosynthesis xanthosine salvage CTZ40_RS28785 PRPP UDP CTP ACP synthase Aromatic Compound Degradation II: fabF NADP-dependent ribonucleoside- adenine a (3R)-3- a [biotin carboxyl- isocitrate dehydrogenase: gln hydrogencarbonate IMP xanthosine peptidoglycan biosynthesis I Cell Structure Biosynthesis an (S-diacyl-sn- (5Z,8Z,11Z,14Z,17Z) DNA containing a dipetide with an N- a 6-(N-acetyl-α- (R)-methylmalonyl- 1-oleoyl-sn thiamine RS10895 thiamine diphosphate reductase: purine-nucleoside vancomycin resistance I peptidoglycan maturation (meso-diaminopimelate containing) hydroxyhexanoyl-[acp] a (9Z)-3-oxohexadec- carrier-protein dimer]- CTZ40_RS33635 superpathway of an L-1- adenosylcobinamide- phenyl ribotide a cis,cis-delta3,15- adenosylcobinamide- α-ribazole raffinose coenzyme A a single a ribonucleoside methylglyoxal xylitol a phosphate nitrate amidophosphoribosyltransferase: CDP (meso-diaminopimelate containing) protocatechuate degradation 4-sulfocatechol gentisate degradation I chlorpyrifos degradation glyceryl)-L-cysteinyl- a malonyl-[acp] a purine 2'- D-glucosaminyl)- -glycerol 3- CTZ40_RS13265 6 phenylethylamine GDP phosphate GDP -icosapentaenoate a base with lesion terminal L-aspartate dGTP CoA IDP CTZ40_RS21015 phosphorylase: purine-nucleoside 9-enoyl-[acp] N -biotinyl-L-lysine II (ortho-cleavage pathway) phosphatidylethanolamine C34:2-[acp] alpha-glucosidase/ long-chain fatty stranded DNA triphosphate deoxyribonucleoside monoester glutamine-hydrolyzing IMP UDP-N-acetyl- lipid II (meso NADP-dependent oleate β-oxidation Fatty Acid and Lipid Degradation degradation [apolipoprotein] apolipoprotein N- adenosylcobinamide- beta-ketoacyl- adenosylcobinamide- bifunctional G/U mismatch- dipeptidase: 1-phosphatidyl- glyoxalase/bleomycin NAD(P)- methylmalonyl- phosphate alkaline respiratory CTZ40_RS13270 ribonucleoside- CTZ40_RS14675 phosphorylase: androstenedione degradation degradation alpha-galactosidase: purine-nucleoside 1-acyl-sn-glycerol- nucleoside- carbamoyl-phosphate dehydrogenase: α-D-glucosamine D-alanyl-D-alanine diaminopimelate containing) 3-oxoacyl- acetyl-CoA isocitrate dehydrogenase: acyltransferase: lnt GDP ACP synthase II: GDP acid--CoA ligase: specific DNA CTZ40_RS13505 1D-myo-inositolGlcNAc-PI de- resistance protein/ dependent alcohol CoA mutase nitrate reductase: vitamin B12-dependent diphosphate reductase: adenosine CTZ40_RS14675 pyruvate gentisate chlorpyrifos DNA primase/ phosphorylase: nucleoside triphosphate 3-phosphate phosphatase: β gly synthase: carA carB guaB [acyl-carrier- carboxylase CTZ40_RS15305 2-phenylethylamine protocatechuate 4-sulfocatechol ribazoletransferase: CTZ40_RS33550 CTZ40_RS18745 glycosylase: N-acetylase: dioxygenase: dehydrogenase: subunit beta: CTZ40_RS02290 diphosphate 5-phospho- -D-ribosylamine xanthine UDP-N-acetylglucosamine peptidoglycan biotin carboxylase: aryldialkylphosphatase: apolipoprotein N- ribazoletransferase: CTZ40_RS33630 polymerase: dipeptidase: 6-(α-D- pyrophosphohydrolase: CTZ40_RS29380 ribonucleotide reductase: CTZ40_RS13265 D-Ala-D-Ala protein] carboxyltransferase oleate primary-amine protocatechuate protocatechuate 2-deoxy-α- CTZ40_RS14675 CTZ40_RS13995 acyltransferase: kinase: D-lactate androst-4-ene-3,17-dione acyltransferase: lnt CTZ40_RS29995 CTZ40_RS29995 alpha-galactosidase: [+ 11 isozymes] CTZ40_RS11100 CTZ40_RS37140 CTZ40_RS34745 CTZ40_RS10075 CTZ40_RS24475 CTZ40_RS07305 CTZ40_RS06285 narH narI CTZ40_RS10085 CTZ40_RS13270 adenosine deaminase: 1-carboxyvinyltransferase: dipeptidase glycosyltransferase: a (2E)-hex-2-enoyl-[acp] CTZ40_RS15775 oxidase: 3,4-dioxygenase: CTZ40_RS11055 an N-acyl-(S-diacyl- beta-ketoacyl- (5Z,8Z,11Z,14Z,17Z) a DNA containing glucosaminyl)- CTZ40_RS06430 [+ 3 isozymes] asp carbamoyl phosphate XMP reductase: subunit: 3,4-dioxygenase: a 2-acyl-1-lyso- phenyl-Coβ- CTZ40_RS34715 a modified D-ribose 1- a purine base a proteinogenic acetate [+ 9 isozymes] [+ 4 isozymes] [+ 2 isozymes] [+ 2 isozymes] CTZ40_RS27015 dUDP CTZ40_RS10825 CTZ40_RS08800 dehydrogenase: VanX: vanX rodA fatty acid-- phosphotriesterase: sn-glyceryl)-L- ACP synthase [+ 6 isozymes] an apurinic/ asp 1-phosphatidyl- an alcohol phosphoribosylamine- vitamin B12-dependent fabG CTZ40_RS15775 CTZ40_RS32870 CTZ40_RS27680 CTZ40_RS27680 3-maleylpyruvate GMP adenosylcobamide GMP adenosylcobalamin α -icosapentaenoyl-CoA nucleobase phosphate [+ 7 isozymes] vanH a nascent peptidoglycan enoyl-ACP CoA ligase phosphatidylethanolamine II: fabF sucrose -D-galactopyranose ssDNA/pppN(pN) apyrimidinic site amino acid 1D-myo-inositol (R)-lactate dGMP D-xylopyranose succinyl-CoA dioleoyl nitrite ITP -glycine ligase: purD ribonucleotide reductase: [+ 3 isozymes] UDP-N-acetylglucosamine a [carboxyl-carrier phenylacetaldehyde protocatechuate CTZ40_RS34790 cysteinyl-[lipoprotein] 5'-phosphate aspartate glutamine- nucleoside-diphosphate with (L-alanyl-γ-D-glutamyl- reductase 3-oxoacyl-ACP family protein: protocatechuate a cis,cis-delta5,17- hybrid phosphatidate 1-carboxyvinyltransferase: D-ala 6 maleylpyruvate diethylthiophosphate acyl-carrier protein n -1 carbamoyltransferase hydrolyzing GMP kinase: CTZ40_RS27015 CTZ40_RS10085 (R)-lactate FabI: fabI protein dimer]-N - 3,4-dioxygenase: 3,4-dioxygenase: inosine XMP murA meso-2,6-diaminopimeloyl-D- reductase: sphingomyelin metabolism CTZ40_RS22880 phenylacetaldehyde isomerase 3-oxo-C36:2-[acp] GAR catalytic subunit: synthase: guaA CTZ40_RS28785 carboxybiotinyl-L-lysine androsta-1,4-diene-3,17-dione pcaG pcaH pcaG pcaH dUTP dCDP UDP-N-acetyl-α- alanyl-D-alanine) pentapeptide enoyl-ACP [+ 11 isozymes] dehydrogenase: 3-carboxy-cis family mycothiol- CTZ40_RS34255 a (3R,9Z)-3- 3-sulfomuconate nucleoside-diphosphate purine-nucleoside D-glucosamine- D-alanine-- reductase an N-acyl- CTZ40_RS14715 ,cis-muconate dependent phosphoribosylglycinamide dUTP diphosphatase: hydroxyhexadec- oleoyl-CoA 4-methylphenyl p-nitrophenyl-α-D- 3-(4- 4-amino-2-(methanethioyl)- (12Z,15Z)-9,10- an [RNA]-3'- a peptide with 6-O-trans- GMP (R)-lactate D-alanyl-D-alanine D-alanyl-D-alanine FabI: fabI sphingosylphosphorylcholine + (2E,6Z,9Z,12Z,15Z,18Z) a [protein]-L- formyltransferase: CTZ40_RS09795 kinase: CTZ40_RS27015 phosphorylase: enolpyruvate 3-carboxy- 3-sulfomuconate enzyme: fenamiphos adenosylcobinamide- a glutaryl-[acp] [DNA] FMN NAD(P)H H (E)-2-hexenol [DNA] long chain N-carbamoyl-L-aspartate 9-enoyl-[acp] phenylacetate ribotide a malonyl-[acp] galactopyranoside hydroxyphenyl) pimeloyl-CoA ala 5-oxo-3-sulfanylpyrrolidine- epoxyoctadeca- ribunucleoside- an N-terminal methoxy-mycolyl- methionine ligase: vanA carboxypeptidase/ carboxypeptidase/ cis,cis-muconate cycloisomerase: CTZ40_RS20130 diethylphosphate GDP methyl ester -tetracosahexaenoyl-CoA dATP polyphosphate CTZ40_RS15335 nucleoside triphosphate dCTP CTZ40_RS14675 UDP-N- acyl-CoA 9α-hydroxyandrosta- aryldialkylphosphatase: phosphate alpha-glucosidase/ exodeoxyribonuclease NADPH-dependent crotonase/enoyl- pyruvate 2-carboxylate 12,15-dienoate 2',3'- NAD(P)- bifunctional trehalose 6- peptide- guanylate kinase: D-alanyl-D-alanine- D-alanyl-D-alanine- a mature peptidoglycan with a hexanoyl-[acp] sphingomyelin adenosylcobinamide- beta-ketoacyl- 4-hydroxyphenylpyruvate 8-amino-7- lantibiotic epoxide hydrolase: L-methioninetype I methionyl pyrophosphohydrolase: acetylmuramate dehydrogenase: phenylacetate-- cycloisomerase: pcaB [+ 9 isozymes] alpha-galactosidase: dihydroorotase: CTZ40_RS41560 endopeptidase: dacB endopeptidase: dacB (L-alanyl-γ-D-glutamyl-meso- phosphodiesterase: 1,4-diene-3,17-dione CTZ40_RS11055 GDP ACP synthase II: III: xth FMN reductase: ssuE CoA hydratase biosynthesis CTZ40_RS00240 cyclophosphate nucleoside triphosphate aminopeptidase: dependent alcohol DNA primase/ polyphosphate phosphate methionine FGAR hypoxanthine dehydrogenase: pcaB CTZ40_RS33550 dioxygenase: hppD oxononanoate RNA 2',3'-cyclic trehalose- CTZ40_RS24475 D-alanyl-D-lactate beta-ketoacyl- CTZ40_RS08870 CoA ligase: paaF phosphotriesterase: CTZ40_RS33630 exodeoxyribonuclease NADPH-dependent family protein: protein: dehydrogenase: polymerase: kinase 2: ppk2 (S)-S-oxide CTZ40_RS34260 guanylate kinase: penicillin-binding penicillin-binding 2,6-diaminopimeloyl-D-alanyl- sph (2-carboxy- 4-sulfomuconolactone 3-fumarylpyruvate ribazoletransferase: 4-hydroxyphenylpyruvate synthase: epoxide hydrolase: phosphodiesterase: pyrophosphohydrolase: map phosphatase: CTZ40_RS22125 a (2E,9Z)-hexadeca- sphingosylphosphorylcholine [+ 32 isozymes] CTZ40_RS35330 CTZ40_RS07305 CTZ40_RS11100 reductase phosphoribosylformylglycinamidine CTZ40_RS34295 dUMP protein 2: mrdA protein 2: mrdA D-alanine) pentapeptide ACP synthase II: 2,5-dihydro- CTZ40_RS34790 CTZ40_RS29995 alpha-galactosidase: III: xth FMN reductase: ssuE CTZ40_RS37250 (5E)-3-amino-4-sulfanyl-CTZ40_RS09030 CTZ40_RS40290 thpR CTZ40_RS24475 [+ 2 isozymes] otsB UDP-N- 2,9-dienoyl-[acp] phenylacetyl-CoA 3-methyl-4- 4-methylphenyl-Co beta-ketoacyl- a 2'- dioxygenase: hppD (12Z,15Z)-9,10- an [RNA]-3'- long chain trehalose- synthase: purS purQ purL (S)-dihydroorotate hypoxanthine CTZ40_RS33630 (2E,9Z)- ethoxy(isopropylamino) CTZ40_RS34715 NAD(P) + FMNH [+ 5 isozymes] 8-amino-7- [+ 4 isozymes] [+ 8 isozymes] MsrA: msrA a sphingosine 3-hydroxy-9,10- 5-oxofuran- (methylsulfanyl) ACP synthase deoxyribonucleoside [DNA] 2 coenzyme A 5-(sulfanylmethylidene) dihydroxyoctadeca- a peptide met a protein-L- FAD-dependent acetylmuramate paraoxon degradation GMP β-adenosylcobamide (3S,6Z,9Z,12Z,15Z,18Z)-3- homogentisate ribunucleoside- a nucleoside 5'- polyphosphate trans-methoxy- GDP phosphoribosyltransferase: hpt a nascent peptidoglycan a nascent peptidoglycan beta-ketoacyl- enoyl-ACP ceramide octadecenoyl-CoA secoandrosta-1,3,5(10) phosphinate 4-nitrophenol D-galactopyranose oxononanoate dAMP (E)-2-hexenal methionine- thymidylate synthase: 1,2-phenylacetyl- 2-yl)-acetate phenol 5'-phosphate II: fabF 5'-monophosphate hydroxytetracosapentaenoyl-CoA pyrrolidin-2-one 12,15-dienoate 2'-phosphate mono-mycolate FGAM quinone-dependent dehydrogenase: with (L-alanyl-γ-D-glutamyl- with D,D cross-links (meso- reductase crotonase/enoyl- a 3-oxopimeloyl- monophosphate CTZ40_RS10420 ACP synthase -triene-9,17-dione CoA epoxidase: 4-carboxymuconolactone fumarate pyruvate acyl-carrier protein (S)-S-oxide dihydroorotate CTZ40_RS39485 CoA hydratase 2-maleylacetate paraoxon [acp] methyl ester IMP meso-2,6-diaminopimeloyl- diaminopimelate containing) II: fabF FabI: fabI CTZ40_RS19885 decarboxylase: pcaC phosphoribosylformylglycinamidine dehydrogenase: dTMP family protein: aryldialkylphosphatase: nucleoside- ribonucleoside- UDP-N-acetyl- D-alanine) tetrapeptide enoyl-ACP paaA 4-carboxymuconolactone cyclo-ligase: CTZ40_RS21020 CTZ40_RS34280 superpathway of pyrimidine ala α glu a 3-oxooctanoyl-[acp] CTZ40_RS35330 CTZ40_RS11055 diphosphate diphosphate dTMP kinase: -D-muramate reductase 2-(1,2-epoxy-1,2- decarboxylase: pcaC nucleobases salvage L,D-transpeptidase: L,D-transpeptidase: 3,4-dihydroxy-9,10- an L-1- cyclic 3-oxo-2-(cis-2'-pentenyl) (9Z,12Z)-15,16- UDP-N-acetyl- (3Z)-hex- a protein-L- CTZ40_RS17580 a mature peptidoglycan FabI: fabI [+ 5 isozymes] dihydrophenyl) (4,5-dihydro- phosphotriesterase: an L-lysyl- a malonyl-[acp] melibionate an (S)-2- a ferrocytochrome L(or D)-O- AIR PRPP orotate kinase: reductase: UDP-N- glutamate CTZ40_RS11925 CTZ40_RS11925 3-oxoacyl-[acyl- secoandrosta-1,3,5(10) diazinon phosphatidyl- a malonyl-[acp] aci-nitroethane stearoyl-CoA a purine dehypoxanthine -cyclopentane-1-(3R- epoxyoctadeca- L-arabinitol α-D-glucosamine an aldehyde myristoyl-CoA methionine- acetyl-CoA 5-oxofuran- CTZ40_RS34790 Lys halocarboxylate 3-en-1-ol CTZ40_RS27015 CTZ40_RS13265 dTDP uracil with D,D cross-links (meso- (S)-3-hydroxy-(9Z) 3-oxoadipate [tRNA ] methyl ester b GTP phosphoserine acetylmuramate-- racemase: a nascent peptidoglycan with a mature peptidoglycan carrier-protein] -triene-9,17-dione aryldialkylphosphatase: sn-glycerol alpha-glucosidase/ nitronate HAD family 5 ribonucleoside futalosine hydroxyhexanoyl)-CoA 9,12-dienoate NAD(P)- UDP-N- NAD(P)- NAD(P)- acyl-CoA (R)-S-oxide orotate L,D-transpeptidase: L,D-transpeptidase: diaminopimelate containing) a palmitoleoyl-[acp] 2-yl)-acetate diethylphosphate 4-nitrophenol bifunctional beta-ketoacyl- acyl-CoA 1,4-dihydroxy- epoxide hydrolase: peptide- 5-(carboxyamino) CTZ40_RS13270 uracil L-alanine ligase: CTZ40_RS34885 γ γ -octadecenoyl-CoA alpha-galactosidase: purine-nucleoside 3-hydroxyacyl-CoA dependent alcohol acetylglucosamine dependent alcohol dehydrogenase: phosphoserine nucleoside-diphosphate CTZ40_RS30135 (L-alanyl- -D-glutamyl-meso- CTZ40_RS30135 with (L-alanyl- -D-glutamyl- reductase: fabG β-ketoadipate CTZ40_RS11055 lysylphosphatidylglycerol ACP synthase II: monooxygenase: hydrolase: desaturase: 6-naphthoate CTZ40_RS00240 nucleoside triphosphate dependent alcohol methionine imidazole ribonucleotide phosphoribosyltransferase: phosphoribosyltransferase: CTZ40_RS08505 3-hydroxyacyl-CoA CTZ40_RS33550 phosphorylase: dehydrogenase: dehydrogenase: 2-epimerase (non- phosphatase vitamin B12- kinase: CTZ40_RS27015 [+ 3 isozymes] 2,6-diaminopimelate) tripeptide meso-2,6-diaminopimeloyl- 3-oxoacyl-ACP enol-lactone phosphotriesterase: synthetase/lysine-- CTZ40_RS33630 CTZ40_RS27330 CTZ40_RS11320 CTZ40_RS24355 pyrophosphohydrolase: dehydrogenase: dehydrogenase: CTZ40_RS08870 (R)-S-oxide mutase: purE CTZ40_RS20755 CTZ40_RS18350 dehydrogenase: CTZ40_RS14675 synthase: CTZ40_RS19950 epoxide hydrolase: hydrolyzing): GTP dependent UDP-N-acetyl- a nascent peptidoglycan a nascent peptidoglycan D-alanine) tetrapeptide cis-vaccenate (1E,2Z)-3-hydroxy- 2-oxepin-2(3H)- CTZ40_RS34790 alpha-galactosidase: [+ 14 isozymes] α CTZ40_RS07305 CTZ40_RS07305 CTZ40_RS37435 [+ 32 isozymes] SerB: serB dTTP reductase: hydrolase: 2-isopropyl-6- tRNA ligase LysX: lysX beta-ketoacyl- [unspecified [+ 3 isozymes] [+ 2 isozymes] -D-ribose- CTZ40_RS15960 3-oxo-2-(cis-2'-pentenyl) (9Z,12Z)-15,16-CTZ40_RS40290 CTZ40_RS24475 reductase ribonucleotide bifunctional pyr operon α-D-muramoyl- D-glt with L,D cross links (meso- with (L-alanyl-γ-D-glutamyl- CTZ40_RS19950 ylideneacetyl-CoA 3-O-L-lysyl-1-O- CTZ40_RS34715 a (2R)-2- a purine base an unknown 1,4-dihydroxy- [+ 4 isozymes] CTZ40_RS35075 (2E)-tetradec- CTZ40_RS28785 biosynthesis 5,9,17-trioxo-4,5:9,10- pcaC Lys ACP synthase a halide anion a ferricytochrome 1-phosphate -cyclopentane-1-(3- α [+ 4 isozymes] [+ 4 isozymes] MsrB: msrB orotidine 5'-phosphate diethylthiophosphate methylpyrimidin- a tRNA degradation nitrite acetaldehyde hydroxy fatty acid oleoyl-CoA dihydroxyoctadeca- UDP-N-acetyl- - 2-enoyl-CoA serine asp CAIR reductase: transcriptional regulator/uracil L-alanine diaminopimelate containing) meso-2,6-diaminopimeloyl- 3-oxo-(9Z)- disecoandrosta-1 phosphatidylglycerol D-gluconate α-D-galactopyranose b compound 6-naphthoate L-arabinopyranose GMP a [protein]-L- a mature peptidoglycan with palmitoleate II: fabF 5 oxohexanoyl)-CoA D-mannosamine (Z)-3-hexanal an alcohol phosphoribosyltransferase a (3R)-3- octadecenoyl-CoA 3-oxoadipate 4-ol products] 9,12-dienoate CTZ40_RS10085 γ glycine) tetrapeptide a palmitoleoyl-[acp] (10),2-dien-4-oate a 3-oxoglutaryl- methionine orotidine-5'-phosphate PyrR: pyrR UDP-N- (L-alanyl- -D-glutamyl-meso- hydroxyoctanoyl-[acp] acyl-carrier protein phosphoribosylaminoimidazolesuccinocarboxamide beta-ketoacyl- acetyl-CoA C- 3-oxo-5,6- [acp] methyl ester decarboxylase: pyrF UMP acetylmuramoyl- 2,6-diaminopimelate) tripeptide synthase: CTZ40_RS20935 a mature peptidoglycan ACP synthase II: acyltransferase: didehydrosuberyl- L-alanine--D- CTZ40_RS08675 UMP dGDP (d)CMP kinase: with L,D cross-links (meso- a mature peptidoglycan CTZ40_RS33630 CoA semialdehyde cinnamate and 3-hydroxycinnamate SAICAR glutamate ligase: CTZ40_RS32260 diaminopimelate containing) γ 3-[(3aS,4S,7aS)-7a-methyl- degradation to 2-hydroxypentadienoate a [2-oxoglutarate- an (R)-2- an N-formyl-L- 3-oxo-2-(cis-2'-pentenyl) (9Z,15Z)-12,13- an [amino group carrier (d)CMP kinase: with (L-alanyl- -D-glutamyl- beta- (7Z)-hexadecenoyl-CoA (2Z,4Z)-2-hydroxyhexa- a peptidoglycan dimer (generic) cadusafos protoporphyrinogen IX an L-aspartyl- propan-1-ol a uridine in tRNA a 1,4-α-D-glucan CTZ40_RS30475 1,5-dioxo-octahydro-1H dehydrogenase a sulfurated amino-parathion pristanate methionylaminoacyl- -cyclopentane-1-(3R- epoxy-octadeca- gln protein]-C-terminal-γ- repressor LexA HEAT repeat domain- CTZ40_RS32260 nucleoside- UMP kinase: meso-2,6-diaminopimeloyl- a (2E)-oct-2-enoyl-[acp] ketoacyl- 2,4-dienoate SAM halocarboxylate oxaloacetate ITP [tRNA Asn ] GTP -inden-4-yl]propanoate E2 protein] N 6 - [sulfur carrier] aryldialkylphosphatase: fatty acid--CoA lytic transglycosylase aryldialkylphosphatase: HAD family tRNA protoporphyrinogen hydroxybutanoyl)-CoA 9,15-dienoate (L-glutamyl)-L-glutamate NAD(P)- tRNA 1,4-alpha- containing protein: diphosphate CTZ40_RS10915 glycine) tetrapeptide ACP acyl-CoA 3-oxo-5,6- cinnamate peptide epoxide hydrolase: amino acid racemase: Asp-tRNA(Asn) UMP kinase: UDP-N-acetyl- acyl-CoA lipoyl ligase family protein: domain-containing hydrolase: phosphoenolpyruvate oxidase: hemG 3-hydroxyacyl-CoA transcriptional glucan kinase: meso- α enoyl-ACP dehydrogenase: didehydrosuberyl- parathion degradation octanoyl-L-lysine CTZ40_RS11055 CTZ40_RS11055 deformylase: CTZ40_RS00240 CTZ40_RS34785 acetylglutamate /Glu-tRNA(Gln) adenylate/guanylate dependent alcohol dihydrouridine CTZ40_RS07110 CTZ40_RS10915 UDP -D-muramoyl-L- synthase synthase: protein: carboxykinase (GTP) dehydrogenase: repressor branching CTZ40_RS27015 diaminopimelate synthetase: bifunctional 3- phosphotriesterase: CTZ40_RS22880 phosphotriesterase: CTZ40_RS11320 protoporphyrinogen kinase: argB amidotransferase: cyclase domain- dehydrogenase: synthase adenylosuccinate alanyl-D-glutamate reductase an (11Z)-3-II: fabF CTZ40_RS08870 CoA lipA a [2-oxoglutarate def : CTZ40_RS14400 epoxide hydrolase: amino-acid racemase: LexA: lexA UDP nucleoside-diphosphate (S)-4-hydroxy- CTZ40_RS35260 phenylpropionate/ CTZ40_RS34790 [+ 11 isozymes] CTZ40_RS14195 CTZ40_RS34790 [+ 12 isozymes] oxidase: hemG CTZ40_RS19950 containing protein: CTZ40_RS07305 DusB: dusB enzyme: FabI: fabI oxooctadec- [+ 32 isozymes] an unsulfurated dehydrogenase bis(sec- [+ 2 isozymes] phosphoenol 3-oxo-2-(cis-2'-pentenyl) (9Z,15Z)-12,13-CTZ40_RS40290 CTZ40_RS11065 an [amino group carrier gatB gatA gatC lyase: CTZ40_RS37145 kinase: CTZ40_RS27015 2-oxohexanoate [+ 3 isozymes] cinnamic acid parathion 5'-deoxyadenosine met [+ 3 isozymes] a (2R)-2- IDP an L-asparaginyl- CTZ40_RS14570 a 5,6-dihydrouridine cleaved glgB nucleoside-diphosphate dGTP Carbohydrate Biosynthesis [sulfur carrier] E2 protein] N 6 4-aminophenol diethylthiophosphate a halide anion a L-methionylaminoacyl- pyruvate protoporphyrin IX -cyclopentane-1-(3- protein]-C-terminal- [+ 4 isozymes] UDP-N- UDP-N-acetyl-D- enoyl-ACP 11-enoyl-[acp] (2E,7Z)- 3-[(3aS,4S,7aS)-7a-methyl- GlcNAc-1,6-anhydro- ethanol butylsulfanyl) hydroxy fatty acid formate dihydroxyoctadeca- D-glutamine Asn in tRNA GDP-mannose biosynthesis dTDP-L-rhamnose biosynthesis dioxygenase AMP diphosphate pristanoyl-CoA a lipid II tRNA γ [tRNA ] cyclic-GMP repressor LexA a GlgE-glycogen AICAR kinase: CTZ40_RS27015 UTP acetylmuramoyl- glucosamine biosynthesis I reductase 3-oxoacyl- hexadecenoyl-CoA -lipoyl-L-lysine phosphinate oxobutanoyl)-CoA 9,15-dienoate -(5-phospho-L- 1-propanal gln 1,5-dioxo-octahydro-1H- trans-2,3- ferredoxin subunit: MurNAc-pentapeptide L-alanyl-D- FabI: fabI [acyl-carrier- aryldialkylphosphatase: glutamyl)-L-glutamate bifunctional UTP CTP synthase: D-ala D-glucopyranose D-glucopyranose α-D-glucopyranose crotonase/enoyl- inden-4-yl]propanoyl-CoA dehydroadipyl-coA CTZ40_RS35560 glutamate--2, 6- protein] CTZ40_RS11055 phosphoribosylaminoimidazolecarboxamide CTZ40_RS32185 6-phosphate 6-phosphate 1-phosphate CoA hydratase (2E)-3-(5,6- diaminopimelate glucose-6- glucose-6- an octanoyl-[acp] reductase: crotonase/enoyl- phosphotriesterase: CTP synthase: D-alanine--D- glucose-1-phosphate family protein: 1-propanal pyruvate dihydroxycyclohexa-1,3- a [pyruvate p-nitrophenyl- 34 a [TusE sulfur 34 3-oxo-2-(cis-2'-pentenyl) an N-terminal L- 527 (E)-2- formyltransferase/IMP cyclohydrolase: purH CTP phosphate UDP-α-D- CoA hydratase 3-hydroxycinnamate CTZ40_RS34790 sn-glycero-3- a Xaa-Pro dipeptidyl- a uridine a uridine a [protein]-S- a guanine L-gulono- an organic a 1,4-α-D-glucan CTZ40_RS32185 ligase: phosphate thymidylyltransferase: fabG CTZ40_RS05300 dehydrogenase a sulfurated coumaphos linoleate β-D-galactoside carrier protein]-S futalosine -cyclopentane-1-(3R- alanyl-[S5 protein methylcrotonoyl- L-homocysteine a protein alanine ligase: galactose 5-hydroxy-3-[(3aS,4S dien-1-yl)prop-2-enoate SAM phosphoethanolamine in tRNA in tRNA sulfanyl-L-cysteine in 16S rRNA ATP 1,4-lactone hydroperoxide inosine-5'-phosphate biosynthesis I CTZ40_RS30460 isomerase: isomerase: beta-ketoacyl- family protein: 6 beta-glucosidase: peptidase substrate 1,4-alpha- FAICAR CTZ40_RS35915 CTZ40_RS01890 3-oxoacyl-ACP [+ 5 isozymes] E2 protein] N - [sulfur carrier] aryldialkylphosphatase: fatty acid--CoA glycerophosphodiester Xaa-Pro dipeptidyl- -sulfanylcysteinetRNA 2- futalosine tRNA 2- hydroxyoctanoyl)-CoA of 30S ribosome]ribosomal- 16S rRNA CoA SMP-30/ thioredoxin- CTZ40_RS31335 CTZ40_RS31335 biosynthesis ACP synthase II: ,5R,7aS)-7a-methyl-1,5- CTZ40_RS05300 lipoyl 3-hydroxyacyl-CoA crotonase/enoyl- CTP guanine and guanosine salvage II reductase: 4-nitrophenol octanoyl-L-lysine CTZ40_RS11055 ligase family protein: phosphodiesterase: CTZ40_RS26090 thiouridine(34) hydrolase: thiouridine(34) (guanine(527)-N(7) homocysteine S- adenylate/guanylate gluconolactonase/ dependent thiol glucan D-alanine--D- F6P F6P [+ 2 isozymes] (S)-3-hydroxy-(7Z) dioxo-octahydro-1H- diethylthiophosphate peptidase: protein-alanine N- CoA hydratase endopeptidase: UDP-N-acetyl- dTDP-α-D-glucose trehalose biosynthesis I UDP-α-D-glucose CTZ40_RS33630 CTZ40_RS28785 [+ 5 isozymes] synthase: CTZ40_RS22880 CTZ40_RS10830 beta-glucosidase: CTZ40_RS15955 synthase dehydrogenase: )-methyltransferase methyltransferase: cyclase domain- peroxidase: branching bifunctional superpathway of AIR alanine ligase: -hexadecenoyl-CoA inden-4-yl]propanoyl-CoA (3S)- a [pyruvate phosphotriesterase: CTZ40_RS05865 synthase acetyltransferase: LRE family protein: CTZ40_RS29820 α-D-muramoyl- UDP-glucose beta-ketoacyl- a (3R,11Z)-3- propanoyl-CoA lipA CTZ40_RS19950 family protein: mmuM enzyme: adenosine nucleotides 5-(carboxyamino)imidazole mannose-6- dTDP-glucose 4,6- CTZ40_RS34790 [+ 11 isozymes] [+ 6 isozymes] CTZ40_RS27485 a dipeptide with a MnmA: mnmA MnmA: mnmA 7 RsmG: rsmG containing protein: CTZ40_RS33000 CTZ40_RS25705 phosphoribosylaminoimidazolecarboxamide CTZ40_RS11235 glutamine-- hydroxyadipyl- an unsulfurated dehydrogenase a peptide a [TusE sulfur dehypoxanthine 34 3-oxo-2-(cis-2'-pentenyl) an N-terminal N-acetyl-rimI an N - L-alanyl-γ-D- D-glucopyranose 4-epimerase ACP synthase hydroxyoctadec- 3-hydroxyacyl-CoA 2,3-dihydroxy-trans-cinnamate 5'-deoxyadenosine met 34 hypoxanthine a [protein]- a 2-thiouridine CTZ40_RS05300 glgB asp de novo biosynthesis I ribonucleotide synthase: guanosine phosphate dehydratase: rfbB α 6 sn-glycerol C-terminal L-proline a 2-thiouridine 527 CTZ40_RS14570 an alcohol formyltransferase/IMP cyclohydrolase: purH fructose-6- UDP- -D-glucose dehydrogenase: CoA [sulfur carrier] E2 protein] N diethylthiophosphate chlorferone ethanolamine D-galactopyranose 4-nitrophenol carrier protein]- futalosine -cyclopentane-1-(3- L-alanyl-[S5 protein methylguanine [+ 5 isozymes] met [+ 2 isozymes] a peptide CTZ40_RS24815 glutamyl-meso-2,6- D-alanyl-D-alanine 6-phosphate GalE: galE II: fabF 11-enoyl-[acp] AMP diphosphate linoleoyl-CoA 3-phosphate in tRNA L-cysteine in tRNA cyclic-AMP starch phosphate isomerase: dTDP-glucose 4,6- trehalose-6- CTZ40_RS19950 3-hydroxyacyl-CoA -lipoyl-L-lysine L-cysteine oxooctanoyl)-CoA of 30S ribosome] in 16S rRNA 3-hydroxyisovaleryl- L-gulonate N5-CAIR diaminopimelate UDP-glucose (2E)-3-[(3aS,4S,5R,7aS) methyl parathion degradation asp IMP transaminase CTZ40_RS38210 dehydratase: rfbB phosphate dehydrogenase: diethylphosphate CoA 4-epimerase a 3-oxodecanoyl-[acp] 3-oxo-(7Z)- -5-hydroxy-7a-methyl-1- IMP adenylosuccinate UDP-N- (isomerizing) mannose-6- dTDP-4-dehydro-6- synthase: hexadecenoyl-CoA oxo-octahydro-1H-inden- CTZ40_RS19950 (2Z,4E,7E)-2-hydroxy- 5-(carboxyamino)imidazole guanine GalE: galE a (2E,11Z)- : glmS phosphate deoxy-α-D-glucopyranose α α CTZ40_RS16120 3-oxoacyl-[acyl- methyl parathion synthetase: ribonucleotide mutase: purE acetylmuramoyl- , -trehalose UDP-α-D-galactose acetyl-CoA C- 4-yl]prop-2-enoyl-CoA 6-oxonona-2,4,7- undecaprenyl-diphospho-N 966 a uracil 1498 octadeca-2,11- 3-oxoadipyl-CoA a β-D-galactoside α penicillin G a penicillin (3S,6Z,9Z,12Z,15Z,18Z)-3- an alkylated DNA a nucleoside a DNA containing 5'-deoxy-5'- vernolate a guanine (S)-mandelate enterobactin D-mannitol a 1,4-α-D-glucan CTZ40_RS04060 isomerase, dTDP-4- 6-phosphate carrier-protein] triene-1,9-dioate aryldialkylphosphatase: -acetylmuramoyl-L-alanyl-γ- UDP-N-acetyl-α-D-glucosamine -linolenate thr cys tripeptide--D-alanyl- glutamine-- dienoyl-[acp] acyltransferase: hydroxytetracosapentaenoyl-CoA triphosphate a mismatch fluoroadenosine in 16S rRNA in 16S rRNA CAIR hypoxanthine class I: manA dehydrorhamnose reductase: fabG CTZ40_RS11055 D-glutamyl-L-lysyl- D-alanine beta-glucosidase: long-chain fatty penicillin amidase: penicillin amidase: DNA-3- G/U mismatch- purine-nucleoside epoxide hydrolase: 16S rRNA mandelate 16S rRNA enterochelin NAD(P)- 1,4-alpha- IMP dehydrogenase: adenylosuccinate adenylosuccinate superpathway of pyrimidine deoxyribonucleoside salvage D- alanine ligase: fructose-6- trehalose- enoyl-ACP CTZ40_RS08675 undecaprenyldiphospho- 3-hydroxyacyl-CoA nucleoside triphosphate phosphoribosyltransferase: hpt D-mannopyranose 3,5-epimerase: phosphotriesterase: CTZ40_RS26090 acid--CoA ligase: CTZ40_RS35265 CTZ40_RS17560 methyladenine specific DNA phosphorylase: CTZ40_RS00240 (guanine(966)-N(2) racemase/muconate (uracil(1498)-N(3))- esterase: dependent alcohol L-threonine cystathionine glucan guaB synthetase: synthase: CTZ40_RS30465 phosphate phosphatase: 3-oxoacyl-ACP reductase 3-[(3aS,4S,5R,7aS)-5- muramoylpentapeptide beta-N- dehydrogenase: pyrophosphohydrolase: phosphoribosylaminoimidazolesuccinocarboxamide 6-phosphate CTZ40_RS01905 (5Z)-tetradecenoyl-CoA CTZ40_RS34790 beta-glucosidase: CTZ40_RS18745 glycosylase: glycosylase: CTZ40_RS14675 epoxide hydrolase: lactonizing protein: CTZ40_RS09380 dehydrogenase: dehydrogenase: beta-synthase: branching CTZ40_RS04060 CTZ40_RS20820 2'-deoxycytidine transaminase otsB reductase: FabI: fabI acetylglucosaminyltransferase: penicillin amidase: penicillin amidase: CTZ40_RS19950 )-methyltransferase methyltransferase: adenylo-succinate UDP-N- hydroxy-7a-methyl-1-oxo- (2Z)-2-hydroxypenta- CTZ40_RS24475 5-fluoro-5- CTZ40_RS31230 CTZ40_RS24620 enzyme: synthase: CTZ40_RS20935 (isomerizing) phosphomannomutase/ dTDP-4-dehydro- CTZ40_RS28785 4-nitrophenol dimethylthiophosphate CTZ40_RS27485 [+ 11 isozymes] CTZ40_RS17560 CTZ40_RS35265 CTZ40_RS32025 CTZ40_RS37140 CTZ40_RS40290 2 RsmD: rsmD CTZ40_RS33120 3 CTZ40_RS27335 [+ 3 isozymes] CTZ40_RS07305 adenylosuccinate GMP acetylmuramoyl- octahydro-1H-inden-4-yl]- succinyl-CoA fumarate ditrans,octacis-undecaprenyldiphospho-murG (6Z,9Z,12Z,15Z,18Z)-3- a DNA containing (9Z)-12,13- an N - an N - N-(2,3- β-L-rhamnose α,α-trehalose enoyl-ACP acyl-CoA 2,4-dienoate a non galactosylated an alkylated a nucleoside 5'- an apyrimidinic deoxy-D-ribose adenine [+ 4 isozymes] glgB XMP synthase: cytidine deaminase: : glmS phosphoglucomutase: D-galactopyranose phenylacetate 6-aminopenicillanate a carboxylate 6-aminopenicillanate oxotetracosapentaenoyl-CoA uracil methylguanine 966 [+ 2 isozymes] methyluracil 1498 dihydroxybenzoyl) aminoacetone ser HEAT repeat SAICAR tripeptide--D-alanyl- a (3R)-3- reductase dehydrogenase: 3-hydroxypropanoyl-CoA UDP N-acetyl-(N-acetylglucosaminyl)muramoyl- α an apurinic/ monophosphate site in DNA 1-phosphate dihydroxyoctadeca- aldehydo- CTZ40_RS14815 CTZ40_RS24985 dTDP-4- galactose acceptor AMP diphosphate -linolenoyl-CoA nucleobase a glycogen CTZ40_RS20820 domain-containing CMP D- alanine ligase: D-glucosamine hydroxydecanoyl-[acp] FabI: fabI CTZ40_RS10685 3-hydroxyacyl-CoA L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine apyrimidinic site 9-enoate in 16S rRNA (R)-mandelate in 16S rRNA -L-serine D-mannose dehydrorhamnose protein: HEAT repeat domain- dCMP phosphorylation CTZ40_RS39925 6-phosphate mannose-1-phosphate [+ 32 isozymes] dehydrogenase: glutamine-hydrolyzing reductase: rfbD trehalose biosynthesis III a cis- CTZ40_RS07110 containing protein: 2'-deoxyuridine phosphoglucosamine guanylyltransferase/ CTZ40_RS19950 GMP synthase: guaA adenylo-succinate (d)CMP kinase: CMP vaccenoyl-[acp] (2E,5Z)- 3-[(3aS,4S,5R,7aS)-5- Detoxification adenine and UDP-N-acetyl- phosphomannomutase: β α adenylosuccinate CTZ40_RS07110 (d)CMP kinase: mutase: dTDP- -L-rhamnose α -D-glucose ditrans,octacis-undecaprenyldiphospho- XXLG xyloglucan 1402 a glucosylated adenosine salvage I thymidine kinase: CTZ40_RS32260 α UDP- -D-glucose GDP-α-D-glucose tetradecenoyl-CoA hydroxy-7a-methyl-1-oxo- + a D-aminoacyl- (S)-2- a peptide with a MoO - 5'-chloro-5'- a cytidine N-formimino- pyridoxamine an L-glutamyl- HEAT repeat domain- -D-muramoyl- CTZ40_RS22435 CTZ40_RS35705 6-phosphate N-acetyl-(N-acetylglucosaminyl) torulene decanoate oligosaccharide a plastoquinone NAD(P)H H 2 a double stranded DNA trp glycogenin lyase: adenylosuccinate CTZ40_RS32260 biosynthesis I octahydro-1H-inden-4- glu deoxyadenosine in 16S rRNA Gln his a protein GMP CTZ40_RS09870 dCDP L-alanyl-γ-D- α reactive oxygen species degradation D-aspartate beta-glucosidase: [tRNA] aminobutanoate leader sequence molybdopterin ATP L-glutamate 5'-phosphate [tRNA ] containing protein: α-D-glucosamine -D-mannose a (2E)-dec-2-enoyl-[acp] ∆ 3 2 γ carotenoid oxygenase: fatty acid--CoA NAD(P)H-quinone purine-nucleoside 16S rRNA DNA gyrase 1,4-alpha- CTZ40_RS37145 lyase: CTZ40_RS37145 CDP α α -cis-∆ -trans- crotonase/enoyl- yl]-3-oxopropanoyl-CoA superoxide arsenate muramoyl-L-alanyl- -D-isoglutaminyl- D-tyrosyl-tRNA(Tyr) glutamate--cysteine signal cofactor pyridoxamine 5'- Asp-tRNA(Asn) thymidine glutamyl-meso-2,6- di-trans,octa-cis D-glucopyranose , -trehalose CTZ40_RS26090 molybdenum cofactor formimidoylglutamate L-histidine N(alpha) tryptophan 2,3- glucan CTZ40_RS07110 nucleoside- 1-phosphate 1-phosphate CoA hydratase radicals degradation detoxification L-lysyl-D-alanyl-D-alanine D-aspartate ligase: CTZ40_RS16620 ligase family protein: dehydrogenase: deacylase: peptidase I: lepB phosphorylase: (cytidine(1402)-2'-O) subunit A: gyrA phosphate oxidase: endopeptidase adenosine dUMP nucleoside- 6-phosphate enoyl-CoA ligase GCS2: deiminase: /Glu-tRNA(Gln) -methyltransferase: dioxygenase: guanylate kinase: AICAR diaminopimeloyl- -undecaprenyl 6-phosphate enoyl-ACP cis-vaccenate superoxide carotenoid oxygenase: CTZ40_RS22880 beta-glucosidase: CTZ40_RS14665 guanylyltransferase: CTZ40_RS14675 -methyltransferase: type I DNA CTZ40_RS19370 branching adenylosuccinate purine-nucleoside AMP diphosphate kinase: diphosphate bifunctional UDP-N- mannose-1-phosphate phosphomannomutase/ isomerase: family protein: acetyl-CoA C- II (glutaredoxin) ditrans,octacis-undecaprenyldiphospho-CTZ40_RS21935 CTZ40_RS16580 CTZ40_RS35770 [+ 4 isozymes] amidotransferase: La: lon CTZ40_RS41560 thymidine kinase: D-alanyl-D-alanine phosphate trehalose trehalose- reductase CTZ40_RS27485 an uncharged adenylyl CTZ40_RS19980 5-chloro-5- rsmI CTZ40_RS24725 egtD CTZ40_RS20770 enzyme: lyase: CTZ40_RS37145 phosphorylase: bifunctional CTZ40_RS27015 acetylglucosamine guanylyltransferase: phosphoglucomutase: CTZ40_RS05920 CTZ40_RS05300 acyltransferase: superoxide N-acetyl-(N-acetylglucosaminyl)muramoyl- CTZ40_RS19215 [+ 11 isozymes] [+ 2 isozymes] a 2'-O- topoisomerase: [+ 5 isozymes] gatB gatA gatC kinase: biosynthesis V phosphatase: FabI: fabI superoxide dismutase: arsenate XXXG xyloglucan a D-amino acid [+ 2 isozymes] a leader sequence a peptide molybdenum adenine deoxyribose N-Formyl-L- glgB guanylate kinase: CTZ40_RS09870 β + tRNA γ 1402 N-formyl- an L-glutaminyl- CTZ40_RS14675 phosphoribosylaminoimidazolecarboxamide diphosphorylase/ CTZ40_RS35705 α CTZ40_RS24985 CTZ40_RS08675 superoxide L-alanyl-γ-D-isoglutaminyl-N-(β-D- 3-methyl-2-butenal 4'-apo- -carotenal D-galactopyranose NAD(P) a plastoquinol -L-glutamyl-(S)- methylcytidine topA PLP hercynine a peptide dCTP CTZ40_RS27015 phospho-N- -D-glucopyranose otsB [+ 5 isozymes] CTZ40_RS26865 arsenate oligosaccharide cofactor a negatively Gln kynurenine CTZ40_RS34295 adenylate kinase: GDP-α-D- enoyl-ACP dismutase: diphosphate AMP decanoyl-CoA 2-aminobutanoate 1-phosphate L-glutamate [tRNA ] a glycogen AMP adenine formyltransferase/IMP cyclohydrolase: purH glucosamine-1- a glycogen 1-phosphate (3E,5Z)-tetradeca- [+ 2 isozymes] reductase ArsC: asparatyl)-L-lysyl-D-alanyl-D-alanine in 16S rRNA CTP acetylmuramoyl- reductase 3-[(3aS,4S,5R,7aS)- CTZ40_RS26865 supercoiled DNA CTZ40_RS22360 phosphate N- mannose α,α-trehalose 3,5-dienoyl-CoA CTZ40_RS02160 pentapeptide- isoamylase: UTP--glucose- (S)-3-hydroxy-(5Z) acetyl-CoA GDP hypothetical protein: FAICAR acetyltransferase FabI: fabI 5-hydroxy-7a-methyl- hydrogen peroxide [+ 2 isozymes] dTMP transferase: glgX 1-phosphate phosphatidylglycerol -tetradecenoyl-CoA hydrogen arsenite adenylate kinase: CTZ40_RS30705 GlmU: glmU 1-oxo-octahydro-1H- Alcohol Degradation ADP a maltodextrin 3-hydroxyacyl-CoA 2503 XLXG xyloglucan a thiocarboxylated 1402 (11Z)-(S)-3- 6-O-cis-keto- 6-O-cis-methoxy- bifunctional CTZ40_RS30470 uridylyltransferase a decanoyl-[acp] biosynthesis II peroxide adenine 34 a cytidine (2E,9Z)- CTZ40_RS22360 adenine dTMP kinase: α indene-4-carboxyl-CoA a uridine 38-40 in tRNA octanoate NAD(P)H phylloquinone H + carbamoyl a uridine 3-phosphonopyruvate O-succinyl-L- hydantoin (S)-5-hydroxyisourate phosphoribosylaminoimidazolecarboxamide N-acetyl- -D- dehydrogenase: oligosaccharide L-ornithine [SAMP] C- methanethiol hydroxyhexadec- hexadecenoyl-CoA Ins(1)P β-alanine mycolyl-trehalose mycolyl-trehalose a protein nucleoside- CTZ40_RS17580 malto- GalU: galU (non-plastidic) (3E,5Z)- catalase: catalase: in 23S rRNA phosphate in tRNA homoserine in 16S rRNA ribonucleoside- phosphoribosyltransferase: guanine and guanosine salvage glucosamine CTZ40_RS19950 glycerol and glycerophosphodiester degradation 23S rRNA RluA family pseudouridine fatty acid--CoA beta-glucosidase: NAD(P)H-quinone terminal glycine 16S rRNA 11-enoyl-CoA crotonase/enoyl- 6-phosphate 6-phosphate ribonucleoside- formyltransferase/IMP cyclohydrolase: purH undecaprenyldiphospho- beta-ketoacyl- CTZ40_RS12135 CTZ40_RS12135 ethylene glycol ornithine tRNA 2- cystathionine inositol 4-aminobutyrate- snapalysin: diphosphate kinase: diphosphate reductase: CTZ40_RS34110 dTDP 1-phosphate PRPP biosynthesis oligosyltrehalose α DHAP tetradecadienoate glycerol degradation V synthase: CTZ40_RS30550 ligase family protein: CTZ40_RS26090 phosphonopyruvate dihydropyrimidinase: 3-hydroxyacyl-CoA hydroxyisourate trehalose- trehalose- ADP diphosphate N-acetylmuramoyl-L- UDP- -D-glucose ACP synthase II: 3-oxo-(5Z)- [+ 5 isozymes] (adenine(2503)-C(2) dehydrogenase: gamma-synthase: (cytosine(1402)-N(4) CoA hydratase monophosphatase: snpA CTZ40_RS27015 trehalosesynthase: treY NAD(P)-dependent [+ 5 isozymes] arsenite degradation carbamoyltransferase: thiouridine(34) hydA dehydrogenase: -2-oxoglutarate phosphatase: CTZ40_RS13265 reductase: nucleoside- alanyl-γ-D-glutamyl-meso bifunctional UDP-N- (5R,7aS)-5-hydroxy- H O hydroxyl radical )-methyltransferase tRNA pseudouridine(38- CTZ40_RS22880 beta-glucosidase: CTZ40_RS14665 decarboxylase: aepY )-methyltransferase family protein: hydrolase: uraH phosphatase: IMP D-ribose 5- CTZ40_RS33630 tetradecenoyl-CoA 2 a glycerophosphodiester glycerol argF synthase CTZ40_RS14490 CTZ40_RS09830 transaminase: snapalysin: CTZ40_RS13270 AMP guanosine acetylglucosamine abiosynthesis maltooligosyl- IV glycerol-3- 7a-methyl-1-oxo- O glycerol RlmN: rlmN CTZ40_RS27485 RsmH: rsmH CTZ40_RS19950 CTZ40_RS05300 (S)-2-oxo-4- otsB otsB ribonucleoside- CTZ40_RS13265 diphosphate kinase: -2,6-diaminopimeloyl- beta-ketoacyl- acetyl-CoA C- 2 ethylene glycol 40) synthase TruA: truA [+ 11 isozymes] [+ 2 isozymes] MnmA: mnmA an N 4 - (11Z)-3- [+ 2 isozymes] gabT trehalose- snpA phosphate phosphate 2503 XXXG xyloglucan L-citrulline 34 succinate met trehalose-cis-keto- vitamin B12-dependent purine-nucleoside ribose-phosphate trehalose 3,5,6,7-tetrahydro-2H- O a 2-methyladenine 38-40 + phosphonoacetaldehyde diphosphate reductase: CTZ40_RS13270 CTZ40_RS27015 D-alanyl-D-alanine diphosphorylase/ α acyltransferase: 2 a pseudouridine in tRNA D-galactopyranose phylloquinol NAD(P) a 2-thiouridine a [SAMP] C- N-carbamoylglycine 1402 oxohexadecenoyl- [+ 5 isozymes] hydroxy-4-carboxy- cis-methoxy- GTP -maltose ACP synthase dehydrogenase: NAD(P)- 5'-deoxyadenosine met oligosaccharide methylcytidine myo-inositol 3-oxopropanoate mono-mycolate a peptide ribonucleotide CTZ40_RS13265 phosphorylase: UDP-N- glucosamine-1- diphosphokinase: malto- indene-4-carboxyl-CoA glycerophosphodiester glycerol kinase in 23S rRNA diphosphate AMP octanoyl-CoA in tRNA terminal glycine (S)-3-hydroxy-(9Z) 5-ureidoimidazoline vitamin B12- dTTP maltose alpha-D- II: fabF CTZ40_RS11240 CTZ40_RS08675 dependent alcohol in 16S rRNA CoA mono-mycolate reductase: CTZ40_RS13270 CTZ40_RS14675 phosphate N- CTZ40_RS24385 oligosyltrehalose phosphodiesterase: GlpK: glpK dihydroxyacetone -hexadecenoyl-CoA dependent acetylglucosamine- glucosyltransferase: sn-glycerol (3Z)-dodec- dehydrogenase: CTZ40_RS10085 guanine acetyltransferase PRPP trehalohydrolase: CTZ40_RS10830 glycerol kinase vitamin B12-dependent ribonucleotide -N-acetylmuramyl- treS a 3-oxododecanoyl-[acp] 3-phosphate 3-enoyl-CoA CTZ40_RS07305 dihydroxyacetone GlmU: glmU treZ (pentapeptide) α,α-trehalose (5R,7aS)-7a-methyl-1,5- [+ 6 isozymes] GlpK: glpK 6 ribonucleotide reductase: ∆3,∆2-enoyl- [+ 4 isozymes] kinase subunit a 2-oxo a 10- an O - XLLG xyloglucan (1S,2R)-1- (2E,11Z)- a [protein]- 6-O-trans-keto- pyrophosphoryl- UDP-N-acetyl- 3-oxoacyl-[acyl- dioxo-3,5,6,7-tetrahydro- a [protein]- (S)-5-amino-3- acetyl-CoA (3S,6Z,9Z,12Z,15Z,18Z,21Z)-3- an [amino group carrier protein]-C- uroporphyrinogen-III O-succinyl-L- a [protein] Ser/Thr DNA with lesion α-amylose reductase: CTZ40_RS10085 hypoxanthine α,α-trehalose CoA isomerase: glycolaldehyde DhaK: dhaK formyltetrahydrofolate- methylguanine oligosaccharide γ C-(indol-3- glu ala Ins(2)P ethylphosphate L-tyrosine mycolyl-trehalose dGDP undecaprenol N- α-D-glucosamine carrier-protein] 2H-indene-4-carboxyl-CoA carboxylate L-cysteine oxohexanoate hydroxytetracosahexaenoyl-CoA terminal- -(L-ornithyl)-L-glutamate ser octadecenoyl-CoA CTZ40_RS10085 phosphoribosyltransferase: hpt 2-oxoacid:ferredoxin 4a-carbinolamine in DNA beta-glucosidase: homoserine serine/threonine crotonase/enoyl- excinuclease phosphate 6-phosphate 1,4-alpha- a 1-acyl-sn CTZ40_RS05920 sn-glycerol 3-phosphate methylated-DNA-- 3-keto-5- 3-hydroxyacyl-CoA acetylornithine cystathionine yl)glycerol glutamate--cysteine inositol alkaline dADP acetylglucosamine reductase: fabG (5R,7aS)-7a-methyl- DHAP oxidoreductase 4a-hydroxytetrahydrobiopterin CTZ40_RS26090 uroporphyrinogen tryptophan protein kinase: ABC subunit UvrA: protein-tyrosine- trehalose- glucan -glycerol 3- (2E)-dodec- [protein]-cysteine S- aminohexanoate dehydrogenase: transaminase: gamma-synthase: 3-phosphate CoA hydratase monophosphatase: phosphatase: nucleoside- transferase: 3-oxoacyl-ACP 1,5-dioxo-3,5,6,7- dehydratase: decarboxylase: hemE ligase GCS2: phosphatase: phosphatase: branching dADP GMP subunit beta: methyltransferase: beta-glucosidase: cleavage protein: CTZ40_RS33720 synthase: trpB CTZ40_RS15530 family protein: CTZ40_RS16635 CTZ40_RS09830 CTZ40_RS05450 diphosphate kinase: CTZ40_RS12235 phosphate 2-enoyl-CoA tetrahydro-2H- CTZ40_RS06770 CTZ40_RS19950 CTZ40_RS14490 CTZ40_RS35770 otsB nucleoside- reductase: CTZ40_RS21975 CTZ40_RS27485 CTZ40_RS05430 an [amino group carrier protein]- CTZ40_RS30775 [+ 16 isozymes] CTZ40_RS05300 [+ 5 isozymes] CTZ40_RS12515 enzyme: 1-acyl-sn-glycerol- glycolate a reduced 10 CTZ40_RS31160 (6Z,9Z,12Z,15Z,18Z,21Z)-3- D-glyceraldehyde [+ 2 isozymes] [+ 5 isozymes] trehalose- CTZ40_RS27015 CTZ40_RS28785 crotonase/enoyl- indene-4-carboxyl- an N - XXXG xyloglucan (S)-3- γ coproporphyrinogen III succinate L-homocysteine [+ 2 isozymes] DNA without a [protein]- glgB nucleoside- diphosphate + D-galactopyranose C-terminal- -(L-glutamate 5- trp γ-L-glutamyl- a [protein] (L-serine/L- [+ 5 isozymes] undecaprenyldiphospho- 3-phosphate CoA hydratase H ferredoxin [iron- CO an acyl-CoA [+ 2 isozymes] acetoacetate oxotetracosahexaenoyl-CoA 3-phosphate myo-inositol ethanol trans-keto- CoA hydrolase: 2 formyldihydrofolate oligosaccharide aminobutanoyl-CoA (S)-3-hydroxy-(11Z) lesion L-tyrosine diphosphate kinase: kinase: muramoylpentapeptide beta-N- a (3R)-3- DHAP a [protein]-S- semialdehyde-2-yl)-L-glutamate D-alanine threonine) phosphate amylopectin acyltransferase: family protein: CTZ40_RS06095 sulfur] cluster a guanine in DNA mono-mycolate dGTP CTZ40_RS27015 CTZ40_RS27015 methyl-L-cysteine -octadecenoyl-CoA acetylglucosaminyltransferase: hydroxydodecanoyl-[acp] CTZ40_RS11245 CTZ40_RS35330 (3R)-2-(2-carboxyethyl)- murG [+ 7 isozymes] [+ 5 isozymes] 3-methyl-6-oxocyclohex- dATP dATP lipid II (meso a 1,2-diacyl- 1-ene-1-carboxyl-CoA an O 4 - a 2-O-(α-D-mannosyl)-1- N-acetyl-D- diaminopimelate (S)-3- decaprenyl-diphospho-N- UDP-N-acetyl- trans,octacis-decaprenylphospho- phosphoenol 34 Metabolic Regulator Biosynthesis sn-glycerol a [protein]- isobutanoate FMNH NADP + uroporphyrinogen-I 5-aminopentanal (+)-muconolactone glycerol palmitoyl-CoA D-glucopyranose reduced riboflavin a 1,4-α-D-glucan a cytidine (3R)-2-(2- Amine and Polyamine Degradation acetylmuramoyl-pentapeptide α-D-glucosamine β methylthymine phosphatidyl-1D-myo-inositol galactosamine 2 lys a protein containing) 3-phosphate hydroxydodecanoyl-CoA -D-arabinofuranose L-cysteine pyruvate GTP H O in tRNA Ile2 carboxyethyl) undecaprenyldiphospho- decaprenylphospho-beta- in DNA phosphatidylinositol 6-phosphate NADPH-dependent gamma- mandelate 2 NAD(P)- acyl-CoA glucose 1- NADPH- 1,4-alpha- a (2E)-dodec-2-enoyl-[acp] 3-hydroxyacyl-CoA methylated-DNA-- acetate--CoA N-acetylglucosamine- tRNA Secondary Metabolite Biosynthesis ppGpp biosynthesis phosphatidate muramoylpentapeptide beta-N- mannoside phosphoenolpyruvate uroporphyrinogen GTPase dehydrogenase: dependent FMN glucan mannosylglucosylglycerate -3-methyl-6- allantoin degradation D-erythro-pentofuranosid- [protein]-cysteine S- ligase: acs 6-phosphate FMN reductase: ssuE aminobutyraldehyde racemase/muconate dependent alcohol dehydrogenase: proteasome cytidylyltransferase: dehydrogenase: allantoin degradation HflX: hflX lysidine(34) oxocyclohex-1- N-acetylglucosamine superpathway of 4- acetylglucosaminyltransferase: 2-ulose 2-reductase: acyltransferase: NADPH-dependent mutase: aepX decarboxylase: hemE dehydrogenase: lactonizing protein: dehydrogenase: CTZ40_RS08870 CTZ40_RS06310 reductase: ssuE branching biosynthesis I enoyl-ACP CTZ40_RS10905 CTZ40_RS19950 IV (anaerobic) methyltransferase: deacetylase: nagA synthetase ATPase: arc superpathway of tetracycline and oxytetracycline biosynthesis degradation I aminobutanoate degradation to ureidoglycolate murG CTZ40_RS15070 isobutanoyl-CoA AMP CTZ40_RS34045 D-galactosamine CTZ40_RS10810 CTZ40_RS33120 [+ 5 isozymes] CTZ40_RS07305 [+ 5 isozymes] enzyme: glgB methylerythritol phosphate pathway I methylerythritol phosphate pathway II guadinomine B biosynthesis actinomycin D biosynthesis tunicamycin biosynthesis pppGpp reductase ene-1-carboxyl- CTZ40_RS31160 diphosphate α acetate FMN reductase: ssuE [+ 32 isozymes] [+ 2 isozymes] α TilS: tilS actinorhodin biosynthesis a CDP- I (urea producing) decaprenyl-pyrophosphoryl- trans,octacis-decaprenylphospho- a 2-O-(6-O-acyl- -D-mannosyl)- + (2E)- a (1,6)- -D-glucosyl- 34 3-oxododecanoyl-CoA CoA hydrolase: 6-phosphate + 3-phosphonopyruvate coproporphyrinogen I phosphate GDP H [+ 4 isozymes] D-glucono- a lysidine an unfolded bifunctional (p)ppGpp 3-phospho-D-glycerate FabI: fabI (S)-(+)-allantoin N-acetyl-D- UDP (N-acetylglucosamine)-N- β [+ 2 isozymes] 1-phosphatidyl-1D-myo-inositol H NADPH FMN 5-aminopentanoate cis,cis-muconate riboflavin (1,4)-α-glucan diacylglycerol -D-erythro-pentofuranosid-2-ulose hexadecenoyl-CoA 1,5-lactone Ile2 protein malonyl-CoA UTP glucosyl-3- CTZ40_RS06100 glucosamine 4-aminobutanoate (S)-(+)-allantoin a [protein]-S- L-glyceraldehyde in tRNA pyruvate D-glyceraldehyde 3-phosphate pyruvate D-glyceraldehyde 3-phosphate synthetase/guanosine- enoyl-ACP acetyl-CoA C- acetylmuramyl-(pentapeptide) a thymine in DNA malonyl-CoA ser phosphoglycerate CDP-diacylglycerol-- 9-carboxy-6-methyl-3,7- allantoinase 6-phosphate 4-aminobutyrate- allantoinase methyl-L-cysteine ATP 3',5'-bis(diphosphate) 3'- reductase acyltransferase: N-acetylglucosamine- malonamoyl-CoA 3-hydroxy-4- UDP-N-acetyl- nucleoside triphosphate synthase: glycerol-3-phosphate 3- AllB: allB -2-oxoglutarate deoxyxylulose-5- deoxyxylulose-5- pyrophosphohydrolase: FabI: fabI dioxononanoyl-CoA 6-phosphate AllB: allB methylanthranilate α-D-glucosamine pyrophosphohydrolase: phosphatidyltransferase: CTZ40_RS08675 transaminase: synthetase: asnB a 3,5,7,9,11,13,15- CTZ40_RS10145 α CTZ40_RS16115 D-glucosaminedeacetylase: nagA allantoate (1R,6R)-6-hydroxy-2- 3S-(4-hydroxyphenyl) phosphate synthase: phosphate synthase: CTZ40_RS24475 guanosine 3'- 2-O-( -D-glucopyranosyl) allantoate gabT a single- a dimer of 3-phenyl-2- (11Z)- (5Z)- pgsA decanoyl-CoA seleno-L- isovalerate a D-tryptophanyl- L-threo-3- an insertion sequence D-glucopyranose propanoyl-CoA histidinol hepta-oxo- CTZ40_RS23175 CTZ40_RS23175 bifunctional (p)ppGpp diphosphate 5'- -3-phospho-D-glycerate a dodecanoyl-[acp] acetyl-CoA C- 6-phosphate succinate palmitoyl-CoA a ferrocytochrome b DL-allothreonine non-adjacent hν succinylcyclohexa-2,4- -3-hydroxy- roseoflavin a protein malonamoyl-CoA 1-(3-sn- 5 stranded RNA oxopropanoate [tRNA Trp ] element IS30 ATP hexadecenoyl-CoA dodecenoyl-CoA hexadecanoyl-[PKS-acp] UMP glucosylglycerate acyltransferase: allantoate semialdehyde allantoicase: homocysteine polyribonucleotide 4-hydroxyphenylpyruvate phenylserine diene-1-carboxylate propanoyl-CoA acyl-CoA glucose 1- acyl-CoA [+ 2 isozymes] [+ 2 isozymes] hydrogencarbonate an L-seryl-[L-seryl- synthetase/guanosine- triphosphate 3'- phosphatidyl) acyl-CoA desaturase: serine acetate--CoA thymidines in DNA deoxyribodipyrimidine D-tyrosyl-tRNA(Tyr) low specificity L- transposase: 5'-phosphate acryloyl-CoA histidinol aldo/keto gly arg 3-hydroxy-4- UDP-6-deoxy- biosynthesis I acyl-CoA CTZ40_RS08675 alc 5-methyltetrahydropteroyltriglutamate- 3-hydroxyacyl-CoA dehydrogenase: dehydrogenase: malonamyl-CoA:OxyC bifunctional 3',5'-bis(diphosphate) 3'- diphosphatase: amidohydrolase: succinate- succinate- CTZ40_RS24355 hydroxymethyltransferase: nucleotidyltransferase: ligase: acs photo-lyase: dioxygenase: hppD threonine aldolase: o-succinylbenzoate bifunctional dehydrogenase: dehydrogenase: proteasome: carrier protein] 5,6-ene-N-acetyl- -sn-glycerol dehydrogenase: - homocysteine S- deacylase: dehydrogenase: CTZ40_RS23710 reductase: transferase: reductase: 1-deoxy-D-xylulose 5-phosphate 1-deoxy-D-xylulose 5-phosphate glutamine- methylanthranilyl- pyrophosphohydrolase: 3-phospho- beta-ketoacyl- CTZ40_RS24720 semialdehyde semialdehyde CTZ40_RS10450 4-hydroxyphenylpyruvate riboflavin kinase/ CTZ40_RS08870 CTZ40_RS32835 CTZ40_RS08870 metallophosphatase/ CTZ40_RS10145 2-[2-O-(α-D-mannopyranosyl) GDP-α-D-glucose 3-phosphate CTZ40_RS08870 α-D-glucosamine (S)-ureidoglycolate [+ 2 isozymes] CTZ40_RS11830 CTZ40_RS18015 CTZ40_RS16580 CTZ40_RS34595 synthase: menC [+ 10 isozymes] CTZ40_RS40390 hisD prcB prcA CTZ40_RS02395 CTZ40_RS11560 hydrolyzing glycine adenylate D-glucosamine D-glycerate ACP synthase II: 7-carboxy-4-methyl- dehydrogenase dehydrogenase methyltransferase: metE a nucleoside a single- isovaleryl-CoA AMP diphosphate CTZ40_RS19950 an insertion FAD synthetase: [+ 5 isozymes] 5'-nucleotidase: CTZ40_RS34115 α acetyl-CoA [+ 2 isozymes] dioxygenase: hppD Trp [+ 32 isozymes] [+ 32 isozymes] 1-deoxy-D-xylulose- 1-deoxy-D-xylulose- carbamoyl- amidinotransferase: -(1->2)- -D-glucopyranosyl]- glucosyl-3- CTZ40_RS33630 [+ 32 isozymes] 5-oxoheptanoyl-CoA (S)-ureidoglycine 6-phosphate a ferricytochrome b palmitoleoyl-CoA diphosphate stranded RNA a thymidine in DNA (2-hydroxyphenyl) a tRNA D-tryptophan gly benzaldehyde 3-(4-hydroxyphenyl)- (2E,11Z)-hexadec- (2E,5Z)- [+ 15 isozymes] CTZ40_RS33805 fatty acid elongation -- saturated (NADP(+)): (NADP(+)): 5 2-succinylbenzoate sequence IS30 with CTZ40_RS10595 D-glucono- acryloyl-CoA his 9-hydroxy-3,5,7,11,13,15- 5-phosphate 5-phosphate phosphate CTZ40_RS39820 3-phospho-D-glycerate phosphoglycerate laurate glucosamine- SeMet gly acetaldehyde acetate 3-oxo-propanoyl-CoA roseoflavin adenine 2,11-dienoyl-CoA dodecenoyl-CoA a peptide malonamoyl-[OxyC acyl-carrier protein] a 2-aminomalonyl beta-ketoacyl- (2E)-dec-2-enoyl-CoA putrescine degradation IV CTZ40_RS15615 CTZ40_RS15615 integrated transposon 1,5-lactone hexaoxohexadecanoyl- reductoisomerase: reductoisomerase: synthase: [+ 2 isozymes] synthase: an L-1- 6-phosphate dinucleotide semialdehyde-[L- a 3-hydroxy-4- UDP-6-deoxy- ACP synthase fatty acid-- [PKS-acp] CTZ40_RS10675 CTZ40_RS10675 carA carB guanidinoacetate 2-O-(α-D-CTZ40_RS16115 phosphatidyl- an acetoacetyl-[acp] deaminase: succinate tetracycline polyketide methyl-anthranilyl- 5,6-ene-GalNAc uridine II: fabF crotonase/enoyl- seryl-carrier protein] α CoA ligase sn-glycerol (2E)-7-carboxy-4-methyl- putrescine urea degradation II synthase beta-ketoacyl GTP ppGpp 2-[2-O-( -D- glucopyranosyl) CoA hydratase nagB 2,5-diamino-6-(5- an intrastrand non- a dimer of adjacent (11Z)-3- (S)-3- 46 [AcmD acyl- thr val family protein: (S)-ureidoglycolate 3-aci- (2E,6E)-farnesyl α 2,5-dichloro-trans a guanine synthase subunit OxyA: oxyA MEP MEP carboxyphosphate mannopyranosyl)-(1->2)-α- -3-phospho- 5-oxohept-2-enoyl-CoA phospho-D-ribitylamino) 2-hydroxyethylphosphonate ν thymidine and 2'- hν protoheme phytanoyl-CoA 2-oxoglutarate an N -methyl hydroxytetradecanoyl- trans-aconitate palmitoleoyl-CoA squalene a 28S rRNA pivalyl-CoA a DNA segment squalene carrier protein] CTZ40_RS22880 family protein: F6P nitropropanoate adjacent cyclobutane h diphosphate oxohexadecenoyl- -dienelactone in tRNA D-glucopyranosyl]-D-glycerate D-glycerate a 3-oxotetradecanoyl-[acp] crotonase/enoyl- pyrimidin-4(3H)-one phytanoyl-CoA L-amino acid CoA tRNA acyl-CoA squalene a (3'-hydroxy-2'- CTZ40_RS35330 urea bifunctional nitronate thymidine dimer in DNAdeoxyribodipyrimidine deoxycytidine in DNA deoxyribodipyrimidine protoheme IX CoA acetyl-CoA C- N-methyl-L- dienelactone trans-aconitate 2- squalene--hopene RICIN domain- isobutyryl-CoA recombinase 2-C-methyl-D- 2-C-methyl-D- [+ 11 isozymes] CoA hydratase phosphonoacetaldehyde 3-hydroxyacyl-CoA nonaketamide-[OxyC acyl-carrier protein] (3''-oxobutanoyl) glutamine- an aminomalonyl-[L- guanidinoacetyl- UDP-N-acetyl- [+ 5 isozymes] urease: monooxygenase: farnesyltransferase: dioxygenase: (guanosine(46)-N7) dehydrogenase: cyclase: shc containing protein: synthase erythritol 4-phosphate erythritol 4-phosphate diaminohydroxyphosphoribosylaminopyrimidine photo-lyase: photo-lyase: acyltransferase: tryptophan dehydrogenase: hydrolase: methyltransferase: mutase A: RecA: recA phenyl)-3,5- hydrolyzing tunicaminyl-uracil nucleoside- 3-oxoacyl-[acyl- lauroyl-CoA family protein: CTZ40_RS37320 reductase: CTZ40_RS37480 CTZ40_RS27330 CTZ40_RS31370 CTZ40_RS02975 -methyltransferase CTZ40_RS08870 squalene--hopene CTZ40_RS35385 HpnC: nonaketamide C9- seryl-carrier protein] [polyketide synthase] a 3-oxoacyl-[acp] (S)-3- 4-aminobutanal deaminase/5-amino-6-(5-phosphoribosylamino) CTZ40_RS18015 CTZ40_RS18015 CTZ40_RS08675 oxidase: solA CTZ40_RS30565 CTZ40_RS24340 CTZ40_RS12260 [+ 2 isozymes] dioxohexanethioate- cytidylyltransferase: cytidylyltransferase: carbamoyl- diphosphate bifunctional (p)ppGpp 2-O-(α-D- carrier-protein] 3-oxoacyl-ACP CTZ40_RS05300 N-carbamoyl- a DNA with adjacent thymidine-2'- (9Z)- CTZ40_RS19950 (E)-3- TrmB: trmB a DNA segment hpnC a 3-hydroxy-4- hydroxydecanoyl-CoA 4-aminobutanoate CTZ40_RS37325 uracil reductase RibD: ribD [+ 2 isozymes] ferroheme o [+ 2 isozymes] an N 7 - [+ 32 isozymes] cyclase: shc [+ 2 isozymes] dehydrogenase: CTZ40_RS16285 CTZ40_RS16285 phosphate kinase: synthetase/guanosine- reductase: fabG reductase: 2-oxoglycine phosphonoacetaldehyde [unspecified 2-hydroxyphytanoyl- acetyl-CoA formaldehyde an L-amino acid 3-oxomyristoyl- 2,5-dichloromaleylacetate (2E,9Z)- a 28S rRNA isovaleryl-CoA presqualene [PKS-acp] methyl-anthranilyl- glucopyranosyl) [+ 5 isozymes] CTZ40_RS37330 5-amino-6-(5-phospho- nonadjacent thymidines deoxycytidine in DNA tetradecenoyl-CoA (methoxycarbonyl) 46 in reverse GDP 3-hydroxyacyl-CoA degradation III nitrite succinate methylguanine hop-22(29)-ene CTZ40_RS02425 4-(cytidine 5'-diphospho) 4-(cytidine 5'-diphospho) synthase: CTZ40_RS27015 3',5'-bis(diphosphate) 3'- CTZ40_RS28785 gamma- D-ribitylamino)uracil degradation 3-oxopropanoate CoA CoA hexadecenoyl-CoA fragments orientation diphosphate L-threonyl-D- N-acetyl- pyrophosphokinase: -D-glycerate 3-oxoacyl-ACP beta- (3R)-7-carboxy-3-hydroxy-4- ammonium pent-2-enedioate in tRNA -2-C-methyl-D-erythritol -2-C-methyl-D-erythritol carA carB pyrophosphohydrolase: dehydrogenase: aminobutyraldehyde putrescine degradation I products] C9-reduced nonaketamide- valyl-[AcmD acyl- gly pro val tunicaminyl-uracil CTZ40_RS34115 reductase: ketoacyl- 3-oxoacyl- methyl-5-oxoheptanoyl-CoA 4-aminobutanoate 4-(cytidine 5'- 4-(cytidine 5'- (2S,3S,7R)-2-amino- sangivamycin CTZ40_RS10145 CTZ40_RS19950 dehydrogenase: [OxyC acyl-carrier protein] 4-(3'-acetyl-5'- carrier protein] CTZ40_RS28785 ACP [acyl-carrier- 3-hydroxyacyl-CoA 1-pyrroline 4-aminobutyrate- diphospho)- diphospho)- carbamate 3-amino-7-hydroxy-8- biosynthesis CTZ40_RS10850 bifunctional (p)ppGpp stearate biosynthesis synthase protein] 3-oxodecanoyl-CoA dehydrogenase: carbamoyl putrescine a 2,3,4-saturated a dimer of adjacent an apo-[LYS2 L- guanine 37 (3Z)-hex- a [protein]-L- phosphoenol tetracycline nonaketamide hydroxy-4'-oxo-1',4'- (2-iminoimidazolidin- a (3R)-3- oxamate -2-oxoglutarate 16-hydroxypalmitate a 10- an L-methionyl- isopenicillin N FMN NADH H + a D-tyrosyl- carbonic acid 2-chloroacetate ethanol wound RNA 2-C-methyl-D- 2-C-methyl-D- CTP 1,2-diacyl-sn- 2'-deoxycytidine and hν asp fumarate Phe ω glutamine- synthetase/guanosine- II (bacteria and plants) II: fabF reductase: CTZ40_RS19950 phosphate gamma- Met 2-aminoadipyl- coenzyme A a PII protein UTP Tyr arg in tRNA 3-en-1-ol proline ( = 180) pyruvate D-ring cyclase/ dihydronapthalen-2'- 4-yl)octanoyl-[GdnH toyocamycin hydroxytetradecanoyl-[acp] transaminase: fatty acid--CoA ligase family formyltetrahydrofolate [initiator tRNA ] NADPH-dependent [tRNA ] carbonic anhydrase: CHAT domain- peptidylprolyl erythritol kinase: erythritol kinase: N-acetyl-D- 3',5'-bis(diphosphate) 3'- fabG acetyl-CoA C- aminobutyraldehyde methionyl-tRNA penicillin amidase: glycerol 3-phosphatephosphatidate thymidine in DNA deoxyribodipyrimidine carrier-protein] L-aspartate [protein-PII] flavodoxin/nitric tRNA haloacid catalase: ATP- pyruvate dehydratase OxyK: oxyK yl)-3-oxobutanoate- hydrolyzing polyketide synthase] beta-ketoacyl- 7-carboxy-4-methyl-3,5- glutamine- gabT holo-ACP synthase: D-tyrosyl-tRNA(Tyr) CTZ40_RS24275 CTZ40_RS24275 glucosaminyl- a (3R)-3- acyltransferase: dehydrogenase: succinate protein: CTZ40_RS22880 formyltransferase: CTZ40_RS35265 FMN reductase: ssuE CTZ40_RS23670 (guanosine(37)-N1) containing protein: isomerase: dehalogenase dependent kinase: pyk [PKS-acp] carbamoyl- 3-hydroxy- pyrophosphohydrolase: a palmitoyl-[acp] a 2,3,4-saturatedACP synthase II: dioxoheptanoyl-CoA 4-aminobutanal cytidylyltransferase: photo-lyase: CTZ40_RS22455 oxidase: uridylyltransferase: deacylase: oxide synthase: CTZ40_RS12135 nonaketamide monocyclic N-acetyl- hydroxyacyl-[acyl- CTZ40_RS08675 hydrolyzing semialdehyde [+ 11 isozymes] penicillin amidase: a holo-[LYS2 L- NADPH-dependent carbonic anhydrase: -methyltransferase CTZ40_RS36105 CTZ40_RS19730 type II: RNA helicase 2-phospho-4-(cytidine 5'- 2-phospho-4-(cytidine 5'- phosphate 4-methyl- CTZ40_RS34115 3-oxo- fatty acyl-[acp] CTZ40_RS10810 an N-formyl- CTZ40_RS34345 CTZ40_RS10905 CTZ40_RS18015 CTZ40_RS17095 CTZ40_RS11080 CTZ40_RS16580 CTZ40_RS01570 [+ 5 isozymes] pyruvate intermediate-[OxyC acyl-carrier protein] tunicaminyl-uracil CTZ40_RS33630 carrier protein] carbamoyl- a CDP-2,3,4-saturated- adjacent 2'-deoxycytidine- 2-aminoadipyl- 3',5'-ADP diphospho)-2-C-methyl-D-erythritol diphospho)-2-C-methyl-D-erythritol sangivamycin gamma- succinate- CTZ40_RS17560 FMN reductase: ssuE a uridylylated Tyr CTZ40_RS30440 1 TrmD: trmD [+ 2 isozymes] [+ 5 isozymes] CTZ40_RS00270 HrpA: hrpA kinase: pyk synthase: anthranilate GDP stearoyl-[acp] octanoyl-CoA acetyl-CoA C- L-methionyl- a tetrahydrofolate succinate 2-iminosuccinate a tRNA D-tyrosine nitric oxide L-citrulline an N - phosphate AMP diphosphate 16-hydroxypalmitoyl-CoA diacylglycerol thymidine in DNA carrier-protein] + (3Z)-hex-3- a [protein]-L- acetaldehyde (2S,3S,7R)-2-amino- pentapeptide aminobutyraldehyde semialdehyde met NAD FMNH PII protein CO H O 37 glycolate an unwound RNA pyruvate tetracycline 2-C-methyl-D- 2-C-methyl-D- carA carB a (2E)-tetradec-2-enoyl-[acp] synthase: fabF acyltransferase: [initiator tRNA ] L-2-aminoadipate 6-aminopenicillanate 2 2 2 methylguanine ω 4-(3'-acetyl-5'- a 3-oxooctadecanoyl- synthase: 4-aminobutanoate en-1-yl acetate proline ( = 0) nonaketamide B/C rings erythritol 2,4- erythritol 2,4- 3-amino-7-hydroxy-8- lactone acyl-CoA dehydrogenase: dehydrogenase in tRNA Phe hydroxy-4'-oxo-1',4'- CTZ40_RS08675 carA carB cyclase/dehydratase: cyclodiphosphate cyclodiphosphate carbamoyl phosphate (2-iminoimidazolidin- phenoxazinone N-acetyl-D- enoyl-ACP [acp] dehydrogenase: CTZ40_RS10850 (NADP(+)): dihydronapthalen-2'- geosmin biosynthesis CTZ40_RS15615 CTZ40_RS02445 synthase: synthase: 4-yl)octanoate synthase: glucosaminyl- reductase 3-oxoacyl- CTZ40_RS08870 5-carboxy-2-methyl- carbamate gamma- an sn-glycero-3- 3 37 yl)-3-oxobutanoate acetyl-CoA a dimer of non-adjacent 37 a dimer of adjacent an N -methyladenine a 2'- a guanine CTZ40_RS16280 CTZ40_RS16280 CTZ40_RS27175 tunicaminyl-uracil FabI: fabI [acyl-carrier- [+ 32 isozymes] 3-oxopentanoyl-CoA aminobutyraldehyde 18-hydroxystearate an adenosine a D-aspartyl- cis-vaccenoyl-CoA nonaketamide tricyclic intermediate- hydroxylacyl-CoA enoyl-ACP succinate 2'-deoxycytidine and hν phospho-N-(acyl) DMAPP pyrimidine hν VibB coenzyme A deoxyribonucleoside [DNA] cys L-homocysteine a glycyl-[tRNA Ala ] 3-oxopropanoate precorrin-6B L-homoserine MeOH trp gly (2E,6E)-farnesyl in tRNA in DNA asp in tRNA [OxyC acyl-carrier protein] dehydrogenase: O-aminophenol enoyl-ACP protein] dehydrogenase: [tRNA ] 2-C-methyl-D-erythritol- 2-C-methyl-D-erythritol- diphosphate reductase a trans-2- (2E)-oct-2-enoyl-CoA fatty acid--CoA ligase family thymidine in DNA ethanolamineglycerophosphodiester tRNA (adenosine(37)-N6) nucleosides in DNA DNA-3- 5'-triphosphate RNA-directed D-tyrosyl-tRNA(Tyr) cystathionine D-tyrosyl-tRNA(Tyr) malonic tRNA acyl-CoA precorrin-6y C5,15- catalase: oxidase: germacradienol reductase reductase: CTZ40_RS10810 deoxyribodipyrimidine deoxyribodipyrimidine holo-ACP synthase: cystathionine CTZ40_RS02420 2,4-cyclodiphosphate 2,4-cyclodiphosphate a 2,3,4-saturated FabI: fabI protein: CTZ40_RS22880 -dimethylallyltransferase methyladenine semialdehyde (guanosine(37)-N1) dehydrogenase: methyltransferase tryptophan 7- glycine (S)-4-(3'-acetyl-5'- (2S,3S,7R)-2,3- fabG enoyl-[acyl- photo-lyase: phosphodiesterase: photo-lyase: CTZ40_RS22455 DNA polymerase: deacylase: beta-synthase: deacylase: CTZ40_RS12135 CTZ40_RS07180 synthase: FabI: fabI fatty acyl-[acp] crotonase/enoyl- [+ 11 isozymes] glycosylase I: reductase: -methyltransferase CTZ40_RS08870 (decarboxylating) gamma-lyase: halogenase: oxidase hydroxy-4'-oxo-1',4'- flavodoxin- flavodoxin- diamino-8-(1-carbamoyl- a tunicamycin enoyl-ACP carrier protein] CO 4-aminobutanoate CTZ40_RS18015 CTZ40_RS10830 MiaA: miaA CTZ40_RS18015 a holo-[VibB aryl- CTZ40_RS02845 CTZ40_RS16580 CTZ40_RS24620 CTZ40_RS16580 [+ 5 isozymes] (1E,4S,5E,7R)-CTZ40_RS29865 3-oxoacyl-ACP CoA hydratase succinyl-CoA propanoyl-CoA 2 a 2'-deoxycytidine N 6 -dimethylallyladenosine 37 two adjacent pyrimidine 3',5'-ADP CTZ40_RS13720 CTZ40_RS14065 TrmD: trmD [+ 32 isozymes] subunit CbiE: cbiE CTZ40_RS19355 CTZ40_RS09600 ThiO: thiO dihydronapthalen-2'- dependent (E)-4- dependent (E)-4- 2-iminoimidazolidin-4- actinomycin D a myristoyl-[acp] reductase a thymidine in DNA [+ 6 isozymes] carrier protein] [DNA] tRNA asp D-aspartate L-cystathionine a tRNA Ala gly an N 1 - 7-chloro-L- germacra-1(10) reductase: family protein: AMP diphosphate 18-hydroxystearoyl-CoA in DNA sn-glycerol an N- in tRNA nucleosides in DNA an apurinic site (2E,11Z)- 2-oxobutanoate formaldehyde glyoxylate pretetramide yl)-3-hydroxybutanoate hydroxy-3-methylbut- hydroxy-3-methylbut- yl)-7-hydroxyoctanoate FabI: fabI 3-methyladenine 3-hydroxypropanoate methylguanine 37 precorrin-8x ,5-dien-11-ol CTZ40_RS28785 CTZ40_RS35330 within DNA octadecenoyl-CoA tryptophan 2-enyl-diphosphate 2-enyl-diphosphate 3-phosphate acylethanolamine in tRNA geosmin synthase: beta-ketoacyl- a (3R)-3- synthase: ispG synthase: ispG [+ 5 isozymes] CTZ40_RS29865 ACP synthase II: hydroxyoctadecanoyl- enoyl-ACP tylosin biosynthesis CTZ40_RS33630 (S)-3- flavodoxin- flavodoxin- [acp] reductase fatty acid β-oxidation I a dimer of non- a peptide with 13 24-hydroxy-3- 2-((1R,3S),-1',9'- (8S,9S,10S)- hydroxyoctanoyl-CoA a dimer of non-adjacent a 1-acyl-2- a uridine (7Z)- dependent (E)-4- dependent (E)-4- 6-dehydroguadinomine B preQ biosynthesis beta-ketoacyl- 2-methylbutanoate [EntF L-seryl- O-phospho- NADH cellulose a primary amine propionamide 6-methylpretetramide dihydroxy-1'-methyl- 0 8,10-dimethyl- FabI: fabI thymidine and 2'- hν O-acetyl-L-serine hydrogen selenide adjacent pyrimidine hν coenzyme A arachidonoyl- an N-terminal L-allo-threonine cys in tRNA oxocholest-4- tetradecenoyl-CoA cys D-ala (S)-methylmalonyl- (2S)- echinomycin and triostin A biosynthesis 3-hydroxyacyl-CoA dGTP carrier protein] CTP L-homoserine endoglucanase: 10'-oxo-3',4',5',10'- hydroxy-3-methylbut- hydroxy-3-methylbut- malonyl-CoA 1-octalin ACP synthase enoyl-ACP deoxycytidine in DNA acetate- nucleosides in DNA sn-glycerol D-amino acid low specificity L- cystathionine tRNA en-26-oyl-CoA NAD(+) acyl-CoA primary-amine amidase: CoA ethylmalonyl-CoA dehydrogenase: a (3Z)-alk-3-enoyl-CoA deoxyguanosinetriphosphate deoxyribodipyrimidine cysteine synthase: deoxyribodipyrimidine holo-ACP synthase: D-aminopeptidase: 3-hydroxyacyl-CoA tetrahydro-1H- 2-enyl-diphosphate 2-enyl-diphosphate tylactone synthase: II: fabF -CoA 3-phosphatephosphatidate diphosphatase: dehydrogenase: CTZ40_RS38385 cystathionine glycine geosmin synthase: reductase photo-lyase: photo-lyase: CTZ40_RS08445 threonine aldolase: gamma-synthase: pseudouridine(13) oxidase: CTZ40_RS32760 synthase: ispG synthase: ispG GTP a (2E)-octadec- CTZ40_RS19950 triphosphohydrolase: ligase: acs CTZ40_RS25630 a holoCTZ40_RS22455-[EntF dehydrogenase: nudC CTZ40_RS08870 secreted cellulase: gamma-lyase: oxidase benzo[g]isochromen- α CTZ40_RS01775 FabI: fabI CTZ40_RS18015 CTZ40_RS18015 cytidylyltransferase: CTZ40_RS34595 CTZ40_RS14490 synthase TruD: truD CTZ40_RS32870 [+ 6 isozymes] dTDP- -D- ATP CTZ40_RS29865 a 3-oxohexadecanoyl-[acp] 2-enoyl-[acp] ∆ 3 -cis-∆ 2 -trans- CTZ40_RS27840 CTZ40_RS19950 β CTZ40_RS19355 ThiO: thiO tylactone quinoxaline- GTP a 2'-deoxycytidine acetate L-selenocysteine a pyrimidine 3',5'-ADP L-seryl-carrier a CDP-1-acyl-CTZ40_RS10905 a peptide a D-amino acid 13 reduced - [+ 32 isozymes] CTZ40_RS07500 3'-yl)acetate (E)-4-hydroxy-3-methylbut- (E)-4-hydroxy-3-methylbut- guadinomine B mycaminose 3-oxooctanoyl-CoA a thymidine in DNA 2-methylbutanoyl- acetaldehyde gly L-cystathionine a pseudouridine 2-carboxylate cyclohydrolase enoyl-CoA 2'-deoxyguanosine triphosphate in DNA AMP diphosphate nucleoside in DNA protein] 2-arachidonoyl- 3,24-dioxocholest- nicotinamide D- AMP (2E,7Z)- an aldehyde propanoate 4-hydroxy-6-methylpretetramide 2-en-1-yl diphosphate 2-en-1-yl diphosphate (-)-geosmin enoyl-ACP CoA in tRNA a cellodextrin pyruvate pyruvate 7,8- 3-oxoacyl-[acyl- isomerase: glycerol 4-en-26-oyl-CoA ribonucleotide tetradecenoyl-CoA quinoxaline-2- I FolE: folE reductase acetyl-CoA C- dihydroneopterin carrier-protein] CTZ40_RS05920 carboxylate FabI: fabI acyltransferase: 4-hydroxy-3- 4-hydroxy-3- 5-O-β- 3'-triphosphate reductase: fabG (S)-DNPA adenylase: enoyl-ACP CTZ40_RS08675 α methylbut-2-enyl methylbut-2-enyl mycaminosyltylactone 2-amino-6-[1-hydroxyethyl]- (6Z,9Z,12Z,15Z,18Z,21Z)-3- a β-Gal-(1->3)-α-Gal-(1->2) 2,3,5,6- (S)-3-hydroxy-(11Z) 3-[(4'- a peptide with 6-O- -mycolyl- CTZ40_RS39440 6-carboxytetrahydropterin 3-oxoacyl-ACP reductase a trans-2-enoyl-CoA a sialyloligosaccharide acetoacetate an apo-[aryl- 3'-ketolactose a [protein] (L-serine/L- cis-dienelactone meso-tartrate 7,8-dihydropterin diphosphate diphosphate hexanoyl-CoA long-chain fatty -[α-(1->6)-oligomannan] coenzyme A a type IV prepilin L-cystathionine an acyl phosphate methylsulfanyl) an N-terminal trehalose 6- 4-dedimethylamino-4-oxoanhydrotetracycline 4-hydroxy-3- 4-hydroxy-3- synthase: CTZ40_RS09135 reductase: crotonase/enoyl- 7-methyl-7,8-dihydropterin oxotetracosahexaenoyl-CoA carrier protein] tetracholorophenol -octadecenoyl-CoA threonine) phosphate quinoxaline-2- FabI: fabI acid--CoA ligase: exo-alpha-sialidase: acetoacetate- acetyl-CoA C- polysaccharide beta-glucosidase: butyl]malate L-alanine phosphate methylbut-2-enyl reductase: ispH methylbut-2-enyl reductase: ispH CTZ40_RS28785 a 2,3,4-saturated CoA hydratase 3-hydroxybutyryl- 2-amino-4-hydroxy-6- holo-ACP synthase: prepilin peptidase: pentachlorophenol cystathionine 3-hydroxyacyl-CoA acylphosphatase: aminopeptidase dienelactone tartrate guanine 4-dedimethylamino-4- toyocamycin 6-carboxy-5,6,7,8- acyl-CoA coenzyme A a (3R)-3- CTZ40_RS29495 -CoA ligase: acyltransferase: CTZ40_RS26090 3-isopropylmalate trehalose- diphosphate 4-hydroxy-3- diphosphate 4-hydroxy-3- carboxyl adenylate fatty acidCTZ40_RS18745 family protein: CoA epimerase: hydroxymethyldihydropteridine pyruvyl transferase: monooxygenase: gamma-lyase: dehydrogenase: calcineurin: CTZ40_RS40375 N: pepN hydrolase: dehydrogenase: deaminase: 5-deoxy- 20-hydroxy-5-O- tetrahydropterin a (3R)-3- a stearoyl-[acp] dehydrogenase: acyl-CoA hydroxyacyl-CoA [+ 2 isozymes] CTZ40_RS35660 CTZ40_RS08675 CTZ40_RS22455 beta-glucosidase: CTZ40_RS14215 dehydrogenase: phosphatase: oxo-anhydrotetracycline reductase: ispH reductase: ispH biosynthesis acyl carrier protein: [+ 10 isozymes] CTZ40_RS05920 diphosphokinase: folK CTZ40_RS08310 CTZ40_RS14885 CTZ40_RS19355 CTZ40_RS19950 CTZ40_RS05330 [+ 2 isozymes] CTZ40_RS30565 CTZ40_RS40005 guaD methylbut-2-enyl methylbut-2-enyl mycaminosyltylactone CTZ40_RS05300 (4Z,7Z,10Z,13Z,16Z,19Z) a holo-[aryl- a cleaved type acylphosphatase: CTZ40_RS11490 otsB transaminase OxyQ: oxyQ dihydrokalafungin CTZ40_RS12635 7-carboxy-7- hydroxyhexadecanoyl-[acp] CTZ40_RS08870 dehydrogenase: [1-(2-amino-7-methyl-4-oxo- N-acetylneuraminate an oligosaccharide acetyl-CoA a 4,6-CH (COO-)C-β-Gal-(1->3)-α- 3',5'-ADP CTZ40_RS27485 a peptide diphosphate diphosphate [+ 5 isozymes] 3 carrier protein] β IV prepilin 2,3,5,6- 2-oxobutanoate cys 3-oxo-(11Z)- CTZ40_RS11140 a peptide ala 2-hydroxy-3- α α 7,8- 4-hydroxy-3- 4-hydroxy-3- preQ deazaguanine [+ 32 isozymes] CTZ40_RS10685 AMP diphosphate acetoacetyl-CoA -docosahexaenoyl-CoA Gal-(1->2)-[α-(1->6)-oligomannan] 3-keto- -D- a [protein] Ser/Thr 7-(methylsulfanyl) 2-maleylacetate , '-trehalose 4-amino-4-de(dimethylamino) 0 [+ 13 isozymes] 7,8-dihydro-3H-pteridin- D-glucopyranose methylbut-2-enyl reductase: methylbut-2-enyl reductase: a 2,3,4-saturated a 2,3,4-saturated (3S galactose tetrachlorohydroquinone octadecenoyl-CoA a carboxylate -2-oxoheptanoate oxosuccinate 6-α-mycolate dihydrolumazine synthase QueE: [+ 32 isozymes] 6-yl)]ethyl diphosphate anhydrotetracycline diphosphate CTZ40_RS14045 diphosphate CTZ40_RS14045 a quinoxaline-2- trans-hex-2-enoyl-CoA fatty acyl CoA )-3-hydroxyacyl-CoA ala carboxyl-[aryl- ser CTZ40_RS39325 22-[(1R,3S)-5,9,10- reductase: isopentenyl- reductase: isopentenyl- 5-phospho-α-D- 20-oxo-5-O-β- stearate carrier protein] 7-carboxy-7- crotonase/enoyl- trihydroxy-1-methyl- CTZ40_RS14045diphosphate CTZ40_RS14045diphosphate ribose-1-preQ mycaminosyltylactone a (2E)-hexadec-2-enoyl-[acp] 3-hydroxyacyl-CoA a dimer of adjacent 2'- RNase III mRNA a dimer of non- 3-oxo-(9Z)- a [protein] N-terminal- 3-[(1- (S)-3-hydroxy-(9Z) a double-stranded 3-[(3'- 7,8-dihydro- IPP IPP 0 deazaguanine ethoprophos a proteinogenic hν [EntB aryl- oxaloacetate sn-glycerol isobutanoyl-CoA urea 15-cis-phytoene 1H,3H,4H-naphtho[2,3- Delta-isomerase: Delta-isomerase: fatty acid-- CoA hydratase dehydrogenase: leukotriene-C4 deoxycytidines in DNA processing coenzyme A adjacent 2'- hexadecenoyl-CoA SAM carboxyvinyl) oligonucleotide methylsulfanyl) 8-oxoguanine 4-methylamino-4-de(dimethylamino) amino acid a tRNA precursor CTP ATP carrier protein] hν formyl-L-methionine -hexadecenoyl-CoA 3-phosphate c]pyran-3-yl]acetate CTZ40_RS05760 CTZ40_RS05760 7-cyano-7- enoyl-ACP CoA ligase family protein: CTZ40_RS19950 aryldialkylphosphatase: deoxyribodipyrimidine substrate deoxycytidines acetyl-CoA C- peptide oxy]benzoate propyl]malate anhydrotetracycline gamma- ribonuclease III: holo-ACP synthase: aminofutalosine 3-hydroxyacyl-CoA phosphoenolpyruvate L-glyceraldehyde isobutyryl-CoA 8-oxoguanine cyanamide phytoene deazaguanine CTZ40_RS35330 CTZ40_RS11055 CCA tRNA photo-lyase: acyltransferase: deformylase: def oligoribonuclease: 3-isopropylmalate reductase family protein: in DNA deoxyribodipyrimidine synthase dehydrogenase: carboxykinase (GTP) 3-phosphate mutase A: deaminase: hydratase: desaturase: [(1R,2R,3S,4S)-4-{5-cyano- dTDP-6-deoxy- 5-O-β- a quinoxaline- a 2,3,4-saturated acetyl-CoA C- a 2,3,4-saturated glutamyltransferase: ggt nucleotidyltransferase: CTZ40_RS11170 CTZ40_RS22455 CTZ40_RS26140 dehydrogenase: synthase: FabI: fabI CTZ40_RS22880 [+ 5 isozymes] phosphotriesterase: an α-(γ-L-glutamyl) CTZ40_RS18015 RNase III photo-lyase: CTZ40_RS08675 [+ 2 isozymes] MqnE: mqnE CTZ40_RS19950 : CTZ40_RS14400 CTZ40_RS12260 CTZ40_RS07740 CTZ40_RS33700 crtI 4-oxo-3H-pyrrolo[2,3- α-D-allose mycaminosyltylonolide 2-carboxyl-D- fatty acyl CoA 3-oxoacyl-CoA leukotriene-D4 two adjacent 2'- a holo-[EntB aryl- (7Z)- an N-terminal L- CTZ40_RS11490 reductase: mgrA DMAPP DMAPP CTZ40_RS09140 [+ 11 isozymes] (S)-3- acyltransferase: CTZ40_RS34790 -L-amino acid a tRNA CTZ40_RS19560 an mRNA fragment processing 3',5'-ADP CTZ40_RS18015 acetyl-CoA formate 6-amino-6- d]pyrimidin-7-yl}-2,3- seryl-L-alanyl- enoyl-ACP deoxycytidines in DNA carrier protein] a 2'-deoxycytidine tetradecenoyl-CoA methionyl-[protein] met 3-oxo-(9Z)- phosphoenol a nucleoside 5'- 6-(methylsulfanyl) L-glyceraldehyde 9,15,9'-tri-cis THN hydroxyhexanoyl-CoA CTZ40_RS08675 containing a product mRNA deoxyfutalosine butanoyl-CoA urate cyanamide anhydrotetracycline preQ reductase ethanol dipropylsulfanylphosphinate in DNA hexadecenoyl-CoA pyruvate monophosphate 3-phosphate -ζ-carotene dihydroxycyclopentyl]methyl cys [non-ribosomal val 0 stearoyl-CoA 3' CCA end -2-oxohexanoate myo-inositol FabI: fabI 3-hydroxyacyl-CoA phosphate dTDP-β-L- peptide synthase] biosynthesis demethyllactenocin dehydrogenase: mycarose phosphatidylserine and a palmitoyl-[acp] CTZ40_RS19950 a mature peptidoglycan phosphoenol an [HPr]- mycothiol- a [mycoredoxin]- 2''-O-acetyl- (5E)-3-oxo- a 2,3,4-saturated 3-[(5'- D-glucopyranose (n) an apo [peptidyl- a single 6-trans-3-oxo- an α-limit dextrin (S)-3-hydroxy-(7Z) (R)-methylmalonyl- D-ribofuranose phosphatidylethanolamine acetyl-CoA (meso-DAP containing) glutathione AsbD acyl- ADP-ribose dodec-5- (3S)-3- methylsulfanyl) L-tartrate acetamide actinorhodin 6-phosphate hypoglycin A pyruvate L-histidine arsenate conjugate L-cysteine coenzyme A coenzyme A stranded DNA tridecenoyl-CoA -tetradecenoyl-CoA L-saccharopine CoA inositol-3- biosynthesis I 3-oxohexanoyl-CoA lytic transglycosylase carrier protein] carrier protein O-acetyl-ADP- 5a,11a-dehydrotetracycline succinylo-toyocamycin phosphoenolpyruvate- mycoredoxin: acetyl-CoA C- 4-alpha- enoyl-CoA 3-hydroxyacyl-CoA hydroxyacyl-CoA pentyl]malate methylmalonyl- gamma- holo-ACP synthase: holo-ACP synthase: acetyl-CoA C- 3-hydroxyacyl-CoA 3-isopropylmalate saccharopine tartrate amidase: ribokinase: phosphate demethylmacrocin triostin A dithiol domain-containing -protein CTZ40_RS13485 deoxyribonuclease acyltransferase: ribose deacetylase: glucanotransferase: phosphate a CDP-diacylglycerol acetyl-CoA C- Nucleoside and Nucleotide Degradation glutamyltransferase: ggt CTZ40_RS22455 acyltransferase: dehydrogenase: dehydrogenase: CoA dehydrogenase: CTZ40_RS39410 synthase: protein: CTZ40_RS14195 phosphotransferase: ptsP a [mycoredoxin] CTZ40_RS22455 IV: CTZ40_RS30335 CTZ40_RS08675 CTZ40_RS07215 dehydrogenase: dehydrogenase: rbsK CDP-diacylglycerol--serine acyltransferase: an [HPr protein]- malQ CTZ40_RS08675 CTZ40_RS19950 CTZ40_RS05960 epimerase: mce CTZ40_RS40005 [+ 6 isozymes] 12-dehydrotetracycline CTZ40_RS19545 L-cysteinylglycine hypoglycin B arsenite mycothiolyl-S-S- a holo [peptidyl- a holo-[AsbD acyl- 4-trans- α CTZ40_RS19950 CTZ40_RS11490 palmitate O-phosphatidyltransferase: [+ 3 isozymes] π 3',5'-ADP 3',5'-ADP acetyl-CoA acetate ADP-D-ribose a -limit dextrin (3E)-dec-3- D-ribofuranose dehydrogenase: CTZ40_RS08675 purine nucleotides degradation II (aerobic) GlcNAc-1,6-anhMurNAc- a mature peptidoglycan N -phospho- pyruvate L-cysteine disulfide carrier protein] carrier protein] undecenoyl-CoA acetyl-CoA 3-oxo-(7Z)- a 2,3,4-saturated 8-(methylsulfanyl) allysine glu (S)-methylmalonyl- 2-hydroxy-3- Ins(3)P superpathway of purine deoxyribonucleosides degradation (n) a 5'-phosphooligonucleotide with short branches enoyl-CoA acetate 5-phosphate CTZ40_RS02465 pssA superpathway of pyrimidine deoxyribonucleosides degradation γ L-histidine tetradecenoyl-CoA 3-oxoacyl-CoA -2-oxooctanoate CoA oxosuccinate fatty acid-- a 3-sn-phosphatidyl- butanoyl-CoA L-Ala- -D-Glu-DAP-D-Ala (meso-DAP containing) 5a,11a-dehydrooxytetracycline L-serine inositol toyocamycin phosphate macrocin triostin A CoA ligase 2'-deoxycytidine AMP 12-dehydrooxytetracycline tetracycline monophosphatase: family protein: phosphatidylserine acyl-CoA 2'-deoxyguanosine 3''-O-acetyl- 3-[(6'- trans,octacis- a 1-O-(alk-1-enyl)-sn-glycero- a peptidoglycan S-methyl-L- 6-cis, 3-oxo- streptomycin an organic D-glucopyranose dehydrogenase: CTZ40_RS09830 CTZ40_RS22880 decarboxylase: dehydrogenase cytidine deaminase: PRPP maltohexaose protoheme a tRNA precursor L-homocysteine ADP-ribose a tRNA precursor maltose 2-hydroxyisobutyramide methylsulfanyl) N-methyl-L- 3-ethylmalate prephenate 2'-deoxyadenosine decaprenyl phosphate 3-phosphoethanolamine methionine tridecenoyl-CoA molecule CTZ40_RS02465 [+ 2 isozymes] [+ 11 isozymes] CTZ40_RS07150 short-chain bifunctional CTZ40_RS14815 decaprenyl-phosphate lysozyme alpha-glucosidase/ deferrochelatase/ acetyl-CoA C- O-acetyl-ADP- alpha-glucosidase/ streptomycin 6- hexyl]malate tryptophan lysoplasmalogenase: ribonuclease Z: homocysteine S- ribonuclease D: amidase: N-methyl-L- 3-isopropylmalate cytochrome P450: prephenate xylose an L-1- specific: metallophosphatase/ precursor: alpha-galactosidase: peroxidase EfeB: efeB acyltransferase: ribose deacetylase: phosphotransferase: 3-isopropylmalate palmitoyl-CoA thymidine phosphoribosyltransferase: CTZ40_RS31830 methyltransferase: alpha-galactosidase: CTZ40_RS32760 tryptophan dehydrogenase: CTZ40_RS09450 dehydratase: isomerase: oxytetracycline myo-inositol toyocamycin tylosin echinomycin CTZ40_RS05530 5'-nucleotidase: purine-nucleoside 2'-deoxyuridine CTZ40_RS31725 CTZ40_RS33550 CTZ40_RS27360 CTZ40_RS07215 CTZ40_RS08665 dehydrogenase: phosphatidylethanolamine CTZ40_RS15055 sn-glycero-3- [+ 2 isozymes] CTZ40_RS08675 CTZ40_RS33550 CTZ40_RS40085 oxidase: solA CTZ40_RS11490 pheA xylA CTZ40_RS33805 adenosine phosphorylase: trans,octacis- a fatty aldehyde a N-acetylmuramoyl- a single-stranded mmuM 4-cis- a nucleoside 5'- [+ 6 isozymes] CTZ40_RS11490 [+ 54 isozymes] [+ 33 isozymes] GMP thymidine phosphoethanolamine N-acetyl-D- maltopentaose 2+ mature tRNA a tRNA IMP CTZ40_RS14675 β pentapeptide- D-glucopyranose Fe protoporphyrin IX oligoribonucleotide acetyl-CoA acetate ADP-D-ribose monophosphate D-glucopyranose 2-hydroxy-2- streptomycin trp formaldehyde 3-phenyl-2- keto-D-fructose [+ 2 isozymes] deaminase: phosphorylase: decaprenylphospho- -D- glucosamine met undecenoyl-CoA 9-(methylsulfanyl) 2-oxovalerate an alcohol purine-nucleoside methylpropanoate 6-phosphate oxopropanoate crotonyl-CoA CTZ40_RS10825 CTZ40_RS14810 ribofuranose 5-phosphate diphosphoundecaprenol -2-oxononanoate bifunctional IMP phosphorylase: uracil phosphorylase: adenosine [+ 3 isozymes] crotonase/enoyl- metallophosphatase/ dehydrogenase: CTZ40_RS14675 CTZ40_RS14810 thymine guaB purine-nucleoside CoA hydratase 5'-nucleotidase: a single all-trans- 3-oxo-2-(cis-2'-pentenyl)- 3-(4-hydroxyphenyl)- a peptide with 3-oxo-(7Z)- a [histone]-N 6 - 3-oxopalmitoyl- β-D-fructofuranose (S)-3-hydroxy-(5Z) 2-chloro-trans 3-hydroxy-4- adenosine phosphorylase: glutathione glycyl-glycine maltoheptaose 2-aminophenol pyrazinamide NAD + cyanate family protein: CTZ40_RS33805 stranded DNA octaprenyl 4-hydroxybenzoate cyclopentane-1-(3-oxobutanoyl)-CoA 3-oxo-propanoyl-CoA an N-terminal tetradecenoyl-CoA acetyl-L-lysine CoA 1-phosphate -dodecenoyl-CoA -dienelactone biotin ATP methylanthranilate deaminase: XMP 2'-deoxyinosine CTZ40_RS14675 exodeoxyribonuclease diphosphate alpha-glucosidase/ acetyl-CoA C- acetyl-CoA C- Xaa-L-proline acetyl-CoA C- histone acetyl-CoA C- class II fructose- CTZ40_RS35330 [+ 2 isozymes] uracil gamma- 4-hydroxybenzoate leucyl 3-hydroxyacyl-CoA dienelactone O-aminophenol O-aminophenol amidase: cyanase: CTZ40_RS10825 α VII: CTZ40_RS14055 alpha-galactosidase: acyltransferase: acyltransferase: acyltransferase: deacetylase: acyltransferase: bisphosphate biotin--[acetyl-CoA- NAD kinase: [+ 5 isozymes] 2-deoxy-α-D-ribose 1-phosphate 2-deoxy- -D-ribose 1-phosphate glutamyltransferase: ggt octaprenyltransferase: aminopeptidase: dehydrogenase: hydrolase: oxidase: oxidase: CTZ40_RS32760 cynS [+ 3 isozymes] CTZ40_RS14060 γ-L-glutamyl- CTZ40_RS33550 CTZ40_RS08675 CTZ40_RS08675 CTZ40_RS08675 CTZ40_RS37400 CTZ40_RS08675 aldolase: fbaA carboxylase] ligase: CTZ40_RS32120 (S)-3- guanosine bifunctional L-cysteinylglycine CTZ40_RS21695 CTZ40_RS29960 CTZ40_RS19950 CTZ40_RS30565 CTZ40_RS07180 CTZ40_RS07180 [+ 6 isozymes] CO ammonium a single-stranded a ribonucleoside a peptide with (5Z)- 2 metallophosphatase/ phosphopentomutase: phosphopentomutase: glycylglycine 3-octaprenyl-4- D-glucopyranose maltohexaose acetyl-CoA (+)-7-epi-jasmonoyl-CoA acetyl-CoA 4-hydroxybenzoyl-CoA a proteinogenic acetyl-CoA acetate a [histone]-L-lysine myristoyl-CoA acetyl-CoA D-glyceraldehyde DHAP 3-oxo-(5Z)- biotinyl-5'- CTZ40_RS14575 pyrazine-2- hydroxybutanoyl-CoA 5'-monophosphate an N-terminal dodecenoyl-CoA + inosine 5'-nucleotidase: CTZ40_RS11070 CTZ40_RS11070 oligodeoxyribonucleotide hydroxybenzoate amino acid 2-chloromaleylacetate actinocin isophenoxazine NADP 3-hydroxyacyl-CoA purine-nucleoside L-proline dodecenoyl-CoA adenylate carboxylate CTZ40_RS33805 dehydrogenase: phosphorylase: purine-nucleoside 2-deoxy-D-ribose 5-phosphate 2-deoxy-D-ribose 5-phosphate CTZ40_RS19950 CTZ40_RS14675 [+ 2 isozymes] phosphorylase: a [glycine-cleavage (6Z,9Z,12Z,15Z,18Z)-3- 3-oxomyristoyl- 3-[(7'-methylsulfanyl) 2-chloro-cis- a monocarboxylic 3,22-dioxochol- maltopentaose D-glucopyranose a 5-L-glutamyl- maltopentaose maltotriose a 1-acyl-2-arachidonoyl- 3-oxo-(11Z)- 3-oxopentanoyl- 3-oxo-(5Z)- SAM complex H protein] a sulfurated [sulfur carrier] an amino acid homogentisate (S)-lactate citrate acetoacetyl-CoA CTZ40_RS14675 guanine xanthosine deoxyribose- deoxyribose-phosphate oxotetracosapentaenoyl-CoA phosphatidylcholine octadecenoyl-CoA CoA CoA dodecenoyl-CoA heptyl]malate dienelactone acid amide 4-en-24-oyl-CoA 6 4-alpha- [peptide] alpha-glucosidase/ alpha-glucosidase/ aldolase: deoC N -octanoyl-L-lysine acetyl-CoA C- phospholipase D: acetyl-CoA C- acetyl-CoA C- acetyl-CoA C- acetyl-CoA C- 3-isopropylmalate dienelactone amidase: acetyl-CoA C- homogentisate lactate 2- aconitate phosphate lipoyl glucanotransferase: malQ gamma- alpha-galactosidase: thiolase domain- hypoxanthine acyltransferase: alpha-galactosidase: CTZ40_RS40315 acyltransferase: acyltransferase: acyltransferase: acyltransferase: dehydrogenase: hydrolase: CTZ40_RS32760 acyltransferase: 1,2-dioxygenase: monooxygenase: hydratase aldolase: deoC synthase: lipA αglutamyltransferase: ggt a 1-acyl-2- containing protein: a [glycine-cleavage maltose maltotetraose an -(5-L- CTZ40_RS33550 CTZ40_RS08675 CTZ40_RS33550 CTZ40_RS08675 CTZ40_RS08675 CTZ40_RS08675 CTZ40_RS08675 CTZ40_RS11490 CTZ40_RS30565 CTZ40_RS32675 CTZ40_RS36810 guanine purine-nucleoside D-glyceraldehyde 3-phosphate an unsulfurated (4Z,7Z,10Z,13Z,16Z)- choline arachidonoyl-sn- (3Z)-dec-3- [+ 6 isozymes] CTZ40_RS08675 AcnA: acnA CTZ40_RS35345 acetaldehyde 5'-deoxyadenosine met complex H protein] a peptide glutamyl)- D-glucopyranose maltotetraose acetyl-CoA D-glucopyranose maltose acetyl-CoA propanoyl-CoA acetyl-CoA acetyl-CoA lauroyl-CoA acetyl-CoA deaminase: phosphorylase: [sulfur carrier] glycerol 3-phosphate palmitoleoyl-CoA 10-(methylsulfanyl) 3-oxo-4-pregnene- 4-maleyl- acetaldehyde D-glyceraldehyde 3-phosphate N 6 -lipoyl-L-lysine amino acid docosapentaenoyl-CoA enoyl-CoA 2-chloromaleylacetate a monocarboxylate acetate D-threo-isocitrate [+ 7 isozymes] guaD CTZ40_RS14675 -2-oxodecanoate 20-carboxyl-CoA acetoacetate acetyl-CoA S-methyl-5'- xanthine 5,10-methylene- 3-methyl-2- a long-linear a dimer of adjacent a [protein]- 5-cis, 7-trans-3-oxo- benzoylsuccinyl- an organic (indol-3-yl) (2S)- acetyl-CoA purine ribonucleosides degradation maltohexaose D-glucopyranose a 1,4-α-D-glucan α-D-glucopyranose hν a [protein]-L-lysine a glucan maltotriose a 3-oxoacyl-CoA ectoine 2-oxoglutarate a cytosine in DNA trans-dienelactone N-ethylglycine chitosan thioadenosine tetrahydromethanopterin oxobutanoate α-D-glucan thymidines in DNA L-glutamine tetradecadienoyl-CoA CoA hydroperoxide acetamide ethylmalonyl-CoA UTP and CTP dephosphorylation I acetyl-CoA thymine degradation 4-alpha- alpha-glucosidase/ 4-alpha- 4-alpha- degradation II 3-methyl-2-oxobutanoate deoxyribodipyrimidine transglutaminase: acetyl-CoA C- benzoylsuccinyl- acetyl-CoA C- ectoine DNA cytosine alkyl hydroperoxide dienelactone amidase: methylmalonyl- glycine glucanotransferase: chitosanase: S-methyl-5'- hydroxymethyltransferase: glucanotransferase: malQ alpha-galactosidase: glucanotransferase: photo-lyase: CTZ40_RS30425 acyltransferase: CoA thiolase: acyltransferase: hydroxylase: CTZ40_RS32760 oxidase UTP thymine adenosine a protein with an methyltransferase: reductase: hydrolase: CoA CTZ40_RS07730 thioadenosine panB maltose maltopentaose CTZ40_RS33550 malQ CTZ40_RS18015 malQ CTZ40_RS08675 CTZ40_RS35640 CTZ40_RS08675 thpD ThiO: thiO S-methyl-5'- a short 1,4- two adjacent N 6 -(γ-glutamyl)- (3Z,5E)-dodec- CTZ40_RS03395 CTZ40_RS14180 CTZ40_RS30565 [+ 6 isozymes] epimerase: mce a 1,4-α-D-glucan D-glucopyranose a glucan a chitosan thioadenosine urate THMPT 2-dehydropantoate D-glucopyranose α-D-glucan acetyl-CoA succinyl-CoA benzoyl-CoA acetyl-CoA an acyl-CoA succinate 5-hydroxyectoine a 5-methylcytosine (2R)- ethylamine glyoxylate CTP synthase: adenosine deaminase: thymidines in DNA L-lysine crosslink 3,5-dienoyl-CoA an alcohol 2-maleylacetate (indol-3-yl)acetate fragment phosphorylase: 5,6-dihydrothymine in DNA ethylmalonyl-CoA CTZ40_RS32185 pyrimidine deoxyribonucleotides CTZ40_RS10825 CTZ40_RS23930 UDP dephosphorylation dihydropyrimidinase: [+ 3 isozymes] 5-MTR-1-P CTP nucleoside triphosphate hydA a 1-(1-alkenyl) a plant soluble 7,8- N-acetyl-β- 4-trans-3-oxo- CTP 5-chloro-trans N-acetyl-D- (2R,3S)-3- dCTP a proteinogenic a maltodextrin D-glucopyranose D-glucopyranose + a ribonucleic acid CTP a phosphatidylcholine xanthosine adenosine inosine guanosine glutathione -sn-glycero-3- heteroglycan NADH H A neuraminate formyl-CoA succinate mannosamine sarcosine a tRNA sec ser pyrophosphohydrolase: 3-(carbamoylamino)- amino acid dihydromonapterin undecenoyl-CoA nucleoside triphosphate -dienelactone isopropylmalate 4-alpha- phosphocholine 4-alpha- NADH dehydrogenase dihydroneopterin ribonuclease PH: acylneuraminate acetyl-CoA C- phospholipase D: formyl-CoA N-acetylneuraminic dCTP deaminase: CTZ40_RS24475 2-methylpropanoate gamma- lysoplasmalogenase: pyrophosphohydrolase: dienelactone 3-isopropylmalate glycine serine--tRNA UMP dCTP dCMP glucanotransferase: malQ glucanotransferase: FAD-containing subunit: aldolase: folB CTZ40_RS25655 cytidylyltransferase: acyltransferase: CTZ40_RS40315 transferase: frc acid synthase: CTZ40_RS20630 CDP glutamyltransferase: ggt CTZ40_RS31830 CTZ40_RS24475 hydrolase: dehydrogenase: oxidase ligase: serS malQ CTZ40_RS11960 6-(hydroxymethyl) a nucleoside CTZ40_RS14855 a 1,2-diacyl- bifunctional purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside an α-(γ-L-glutamyl) maltose a maltodextrin sn-glycero-3- glycolaldehyde CTZ40_RS08675 CTZ40_RS30565 succinyl-CoA formate CTZ40_RS14850 CTZ40_RS11490 ThiO: thiO L-cysteinylglycine a fatty aldehyde a plant soluble a ribonucleic acid CMP-N-acetyl- 2-trans- choline sn-glycerol sec maltose + -7,8-dihydropterin diphosphate CMP N-acetyl-β- dUTP an L-seryl-[tRNA ] metallophosphatase/ dUTP diphosphatase: phosphorylase: phosphorylase: phosphorylase: phosphorylase: -L-amino acid phosphocholine heteroglycan A(H2) NAD β-neuraminate acetyl-CoA 4-methyl-2- methylamine glyoxylate nonenoyl-CoA 3-phosphate 5-chloromaleylacetate neuraminate 5'-nucleotidase: CTZ40_RS09795 (R)-3-amino-2- CTZ40_RS14675 CTZ40_RS14675 CTZ40_RS14675 CTZ40_RS14675 oxopentanoate CMP CTZ40_RS33805 nucleoside triphosphate methylpropanoate [+ 2 isozymes] pyrophosphohydrolase: α bifunctional -D-ribose-1-phosphate a [prokaryotic ubiquitin-like an α(1,5)- 4-fumaryl- (1E,4S,5E,7R)-germacra- dTTP (2R,3S)-2- D-sedoheptulose (S)-2- GDP-α-D- CTP cytidine CTZ40_RS24475 a [protein]-L-lysine maltotetraose D-glucopyranose a sphingomyelin a homogalacturonan a [protein]-L-glutamine serotonin ammonium H O NAD + canavaninosuccinate D-glucopyranose metallophosphatase/ uridine L-arabinan acetoacetate 2 1(10),5-dien-11-ol methylisocitrate mannose dUTP dUMP phosphopentomutase: protein] C-terminal L-glutamate nucleoside triphosphate 1-phosphate hydroxyglutarate cytidine 5'-nucleotidase: 4-alpha- sphingomyelin pectate lyase: alpha-L- transglutaminase: fumarylacetoacetase: nitrite reductase geosmin synthase: argininosuccinate glucose sorbosone methylisocitrate class II fructose- GDP-mannose dCTP deaminase: CTZ40_RS11070 Pup--protein ligase: pafA pyrophosphohydrolase: L-2- deaminase: CTZ40_RS33805 glucanotransferase: malQ phosphodiesterase: sph CTZ40_RS36255 arabinofuranosidase: CTZ40_RS30425 fahA CTZ40_RS29865 lyase: argH dehydrogenase: lyase: prpB bisphosphate 4,6-dehydratase: CTZ40_RS20630 an unsaturated large subunit: nirB CTZ40_RS24475 hydroxyglutarate CTZ40_RS14815 [+ 2 isozymes] N6-([prokaryotic ubiquitin-like protein]- maltotriose CTZ40_RS35170 a [protein] N 6 -[(5-hydroxy-1H CTZ40_RS11565 aldolase: fbaA CTZ40_RS01805 5-hydroxy-CTP 5-hydroxy-CMP D-ribose 5-phosphate maltose phosphocholine a ceramide pectate a homogalacturonan α α acetoacetate fumarate nitrite acetone (-)-geosmin fumarate L-canavanine pyruvate succinate oxidase: lhgO γ-L-glutamyl)-[protein]-L-lysine an (1,5)- -L- -indol-3-yl)ethyl]-L-glutamine dTMP GDP-4-dehydro- UTP uridine oligosaccharide D-glucono- D-erythrose DHAP cytidine L-arabinan arabinofuranose 2-oxoglutarate α 1,5-lactone -D-rhamnose a branched- chain an amino an amino an amino an amino amino acid a dicarboxylate (2-aminoethyl) acid acid acid acid molybdate a branched- a branched- glycine betaine glycine betaine glycine betaine phosphonate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate an amino an amino an amino glycine betaine D-mannitol an inorganic an inorganic chain a C4- a C4- a C4- cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA D-fructose D-fructose D-fructose glutamate glutamate sn-glycerol a basic N-acetyl-α-D- D-glucose 6- a nicotinamide pro pro pro a nucleotide a nucleotide chain benzoate glutamate ethanolamine a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate dicarboxylate dicarboxylate a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA 1-phosphate 1-phosphate 3-phosphate amino acid phosphate mononucleotide acid acid acid gly 1-phosphate anion anion amino acid predicted amino acid dicarboxylate a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA 1-phosphate glucosamine choline choline choline ABC predicted predicted predicted predicted predicted predicted ABC predicted ABC predicted ABC predicted ABC predicted ABC predicted ABC transporter ABC ABC ABC ABC ABC transporter of RS15200 RS08815 RS40740 RS20675 RS16885 RS23665 transporter of transporter of transporter of transporter of RS29510 RS29675 RS08385 RS33560 RS12095 RS13210 RS00645 RS22555 RS24020 RS25430 RS26670 RS27620 transporter of RS29575 of a RS29570 RS12070 RS40000 RS03460 RS37575 RS06710 RS30220 RS35260 RS35325 RS35865 RS18745 RS21760 RS22880 RS04790 RS27280 RS27450 RS06325 RS35025 RS23815 RS25010 RS07440 RS10215 RS26650 RS16245 RS04625 RS08740 RS35675 RS34480 RS33405 RS06825 transporter transporter transporter transporter RS01045 RS21735 RS15215 RS17200 RS25505 transporter (2-aminoethyl) a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate branched- of an of an of an of an of molybdate phosphonate chain α amino acid amino acid amino acid amino acid glycine betaine a branched- a branched- a C4- a C4- cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate N-acetyl- -D- a nicotinamide glycine betaine glycine betaine glycine betaine D-mannitol a nucleotide a nucleotide an inorganic an inorganic a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate amino acid a C4- benzoate cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate D-fructose D-fructose D-fructose sn-glycerol a basic D-glucose ethanolamine an amino an amino chain chain glutamate glutamate glutamate glucosamine pro pro pro gly anion anion a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate dicarboxylate dicarboxylate dicarboxylate a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid 3-phosphate amino acid mononucleotide acid acid an amino (2-aminoethyl) amino acid amino acid choline choline choline molybdate an amino an amino an amino an amino acid phosphonate a branched- acid acid acid acid a dicarboxylate chain amino acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.