SEPT7 Antibody Cat. No.: 19-158

SEPT7 Antibody

Immunohistochemistry of paraffin-embedded rat Immunohistochemistry of paraffin-embedded human lung Intestine using SEPT7 antibody (19-158) at dilution of cancer using SEPT7 antibody (19-158) at dilution of 1:100 (40x 1:100 (40x lens). lens).

Immunofluorescence analysis of HeLa cells using SEPT7 Immunohistochemistry of paraffin-embedded antibody (19-158). mouse kidney using SEPT7 antibody (19-158) at dilution of 1:100 (40x lens).

Specifications

HOST SPECIES: Rabbit

September 29, 2021 1 https://www.prosci-inc.com/sept7-antibody-19-158.html SPECIES REACTIVITY: Human, Mouse, Rat

Recombinant fusion containing a sequence corresponding to amino acids 307-436 IMMUNOGEN: of human SEPT7 (NP_001011553.2).

TESTED APPLICATIONS: IF, IHC, WB

WB: ,1:1000 - 1:2000

APPLICATIONS: IHC: ,1:50 - 1:200

IF: ,1:50 - 1:100

POSITIVE CONTROL: 1) Jurkat

2) HeLa

3) A375

4) HepG2

5) Mouse testis

6) Rat testis

PREDICTED MOLECULAR Observed: 51kDa WEIGHT:

Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: SEPT7.

SEPT7, 7, CDC10, CDC3, Nbla02942, SEPT7A, CDC10 (cell division cycle 10, S. ALTERNATE NAMES: cerevisiae, homolog), CDC10 cell division cycle 10 homolog, cell division cycle 10

GENE ID: 989

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

September 29, 2021 2 https://www.prosci-inc.com/sept7-antibody-19-158.html Background and References

This encodes a protein that is highly similar to the CDC10 protein of . The protein also shares similarity with Diff 6 of and with H5 of mouse. Each of these similar , including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies BACKGROUND: inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on 5, 7, 9, 10, 11, 14, 17 and 19.

ANTIBODIES FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.

September 29, 2021 3 https://www.prosci-inc.com/sept7-antibody-19-158.html