Anthelmintica / Flukicides Order Formula Name Chemical Name Offer No

WITEGA Laboratorien Berlin-Adlershof GmbH James-Franck-Strasse 4 D-12489 Berlin www.auftragssynthese.com [email protected] Tel. +49(0) 30 6392 2195 Fax +49(0) 30 6392 2041 November 13, 2019

Anthelmintica / Flukicides Order Formula Name Chemical Name Offer No. CAS Number

BI002 13 H Thiabendazole-13C6 2-Thiazol-4-yl-1H- 10 mg 13 C13 N N C C [3a,4,5,6,7,7a- 25 mg 13 13 13 C C S C6]benzoimidazole 13 N - C

BI001 Cl N Triclabendazole-D3 5-Chloro-6-(2,3-dichloro- 50 mg S phenoxy)-2-(methyl-D3- N CD thio)-1H-benzoimidazole Cl O H 3 Cl 1353867-93-2

BI013 Cl N Triclabendazole 5-Chloro-6-(2,3-dichloro- 50 mg S phenoxy)-2-methylthio- 100 mg N CH 1H-benzoimidazole Cl O H 3 Cl 68786-66-3

BI014 Cl N O Triclabendazole 5-Chloro-6-(2,3-dichloro- 50 mg S CH 3 sulfone phenoxy)-2-methylsulfo- 100 mg N O nyl-1H-benzoimidazole Cl O H Cl 106791-37-1

BI015 Cl N O Triclabendazole 5-Chloro-6-(2,3-dichloro- 50 mg S sulfoxide phenoxy)-2-methylsulfi- 100 mg Cl O N nyl-1H-benzoimidazole H CH3 Cl 100648-13-3

H BI016 Cl N Ketotriclabendazole 5-Chloro-6-(2,3-dichloro- 50 mg O phenoxy)-1,3-dihydro- 100 mg N benzoimidazol-2-one Cl O H Cl 1201920-88-8

BI036 Cl N Aminotriclabendazole 5-Chloro-6-(2,3-dichlo- 25 mg hydrochloride ro-phenoxy)-1H-benzo- NH2 50 mg O N imidazol-2-ylamine H hydrochloride H Cl Cl Cl 1448346-37-9

WITEGA Laboratorien Berlin-Adlershof GmbH page 1 of 87 Anthelmintica / Flukicides BI072 Hydroxytriclabendazo- 2,3-Dichloro-4-{[6-chloro- 10 mg le-D3 2-(methyl-D3-thio)-1H- 25 mg benzimidazol-5- yl]oxy}phenole

BI049 HO Cl N Hydroxytriclabenda- 2,3-Dichloro-4-(6-chloro- 10 mg S zole 2-methylsulfanyl-3H- 25 mg N CH Cl O 3 benzoimidazol-5-yloxy)- H phenol Cl 109536-21-2 BI003 H 5-Hydroxythiabenda- 2-Thiazol-4-yl-1H- 25 mg HO N S zole benzoimidazol-5-ol 50 mg N N 948-71-0

D BI037 D H Cambendazole-D7 (2-Thiazol-4-yl-1H- 25 mg O N N D S benzimidazol-5-yl)- 50 mg D O carbamic acid isopropyl- D D N N H D7- ester D 1228182-48-6 BI038 H Cambendazole (2-Thiazol-4-yl-1H- 25 mg Me O N N S benzimidazol-5-yl)- 50 mg Me O carbamic acid isopropyl N N H ester 26097-80-3 BI064 H O 2-Aminoflubendazole- 2-Amino-5-(4-fluoroben- 10 mg 13 13 H C N 13C6 zoyl- C6)-1H-benzimi- 13C 13C 25 mg NH2 dazole 13C 13C F 13C H N H - H BI004 O 2-Aminoflubendazole 2-Amino-5-(4-fluorben- 50 mg N zoyl)-1H-benzoimidazol 100 mg NH 2 F N H 82050-13-3 BI020 O Albendazole-D3 (5-Propylsulfanyl-1H- 50 mg S N O H C benzoimidazol-2-yl)- 3 N CD 100 mg H 3 carbamic acid methyl-D3 N ester H 1353867-92-1

BI067 O CH3 Albendazole (5-Propylsulfanyl-1H- 100 mg S N O benzimidazol-2-yl]- H3C NH carbamic acid methyl N ester H 54965-21-8 BI005 O Albendazole-2-ami- 5-(Propane-1-sulfonyl)- 50 mg HCl 1H-benzoimidazol-2- S N nosulfone hydrochlo- H C 100 mg 3 ride ylamine hydrochloride O NH2 N H - O O Albendazole-2- BI035 HCl 2-Amino-5-propyl-D3- 25 mg D S aminosulfone-D3 N sulfonylbenzimidazole 50 mg D NH hydrochloride hydrochloride D 2 N H 1435902-07-0

WITEGA Laboratorien Berlin-Adlershof GmbH page 2 of 87 Anthelmintica / Flukicides

O BI022 O Albendazole sulfone- [5-(Propane-1-sulfonyl)- 50 mg S N O D3 1H-benzoimidazol-2-yl]- 100 mg H3C O N CD carbamic acid methyl-D H 3 3 N ester H 1448345-60-5

BI006 O O Albendazole sulfone [5-(Propane-1-sulfonyl)- 50 mg S N O 1H-benzoimidazol-2-yl]- H3C 100 mg O N CH3 carbamic acid methyl H N H ester 75184-71-3

BI021 O O Albendazole sulfoxi- [5-(Propane-1-sulfinyl)- 50 mg S N O de-D3 H C 1H-benzoimidazol-2-yl]- 100 mg 3 N CD Ricobendazole-D3 H 3 carbamic acid methyl-D3 N ester H 1448346-38-0

BI007 O O Albendazole sulfoxide [5-(Propane-1-sulfinyl)- 50 mg S N O Ricobendazole H C 1H-benzoimidazol-2-yl]- 100 mg 3 N CH3 carbamic acid methyl H N H ester 54029-12-8 BI063 H O Mebendazole-amine- 2-Amino-5-(benzoyl- 10 mg 13 C N 13C6 13 H 13C 13C C6)-1H-benzimidazole 25 mg NH2 13C 13C H 13C H N H - H BI008 O Mebendazole-amine 2-Amino-5-benzoyl-1H- 50 mg HMEB N benzoimidazole 100 mg NH2 N H 52329-60-9 BI028 O Mebendazole-D3 (5-Benzoyl-1H-benzo- 50 mg N imidazol-2-yl)-carbamic H 100 mg N CD acid methyl-D ester 3 3 N O H O 1173021-87-8 OH BI009 O 5-Hydroxymebenda- [5-(Hydroxy-phenyl- 50 mg zole N O methyl)-1H-benzoimi- 100 mg N CH RMEB H 3 dazol-2-yl]-carbamic acid N methyl ester H 60254-95-7

BI029 OH O 5-Hydroxymebenda- [5-(Hydroxy-phenyl- 25 mg zole-D3 N O methyl)-1H- 50 mg N CD benzimidazol-2-yl]- H 3 N carbamic acid methyl-D3 H 1173020-86-4 ester BI010 O Flubendazole [5-(4-Fluoro-benzoyl)- 50 mg N H 1H-benzoimidazol-2-yl]- 100 mg N O CH 3 carbamic acid methyl F N O ester H 31430-15-6 BI027 O Flubendazole-D3 [5-(4-Fluoro-benzoyl)- 50 mg N H 1H-benzoimidazol-2-yl]- 100 mg N carbamic acid methyl-D3 F N O H O CD ester 3 1173021-08-3 BI050 OH O Hydroxyflubendazole {5-[(4-Fluoro-phenyl)- 50 mg

N O hydroxy-methyl]-1H- 100 mg N CH3 H benzoimidazol-2-yl}- F N H carbamic acid methyl 82050-12-2 ester

WITEGA Laboratorien Berlin-Adlershof GmbH page 3 of 87 Anthelmintica / Flukicides BI011 O Oxfendazole (5-Benzenesulfinyl-1H- 50 mg S N H (Fenbendazole benzoimidazol-2-yl)- N O 100 mg CH3 sulfoxide) N carbamic acid methyl O H ester 53716-50-0 BI025 O Oxfendazole-D3 (5-Benzenesulfinyl-1H- 50 mg S H (Fenbendazole N benzoimidazol-2-yl)- 100 mg N O sulfoxide-D3) CD3 carbamic acid methyl-D3 N O ester H 1228182-54-4 BI012 O O Fenbendazole sulfone (5-Benzenesulfonyl-1H- 50 mg S H N benzoimidazol-2-yl)- N O 100 mg CH3 N carbamic acid methyl O H ester 54029-20-8 BI026 O O Fenbendazole (5-Benzenesulfonyl-1H- 50 mg S H sulfone-D3 N benzoimidazol-2-yl)- 100 mg N O CD3 carbamic acid methyl-D3 N O ester H 1228182-49-7 BI024 S N H Fenbendazole-D3 (5-Phenylsulfanyl-1H- 50 mg N O CD 3 benzoimidazol-2-yl)- 100 mg N O carbamic acid H 1228182-47-5 methyl-D3 ester

BI034 S N Fenbendazole-amine 5-Phenylsulfanyl-1H- 50 mg NH hydrochloride 2 benzoimidazol-2-ylamine 100 mg N hydrochloride H HCl 1448346-29-9 BI060 O Hydroxyfenbendazole- [5-(4-Hydroxy-phenyl- 50 mg S N O D3 hydrate (see Data sulfanyl)-1H-benzo- NH CD3 100 mg HO N Sheet) H imidazol-2-yl]-carbamic x mole H2O acid methyl-D3 ester hydrate (see Data Sheet) 1596803-40-5 (anhydrous) BI059 O Hydroxyfenbendazole [5-(4-Hydroxy-phenyl- 50 mg S N O hydrate (see Data NH CH3 sulfanyl)-1H-benzo- 100 mg HO N Sheet) H imidazol-2-yl]-carbamic x mole H2O acid methyl ester hydrate 72447-64-4 (see Data Sheet) (anhydrous)

O H Luxabendazole-D3 BI055 O N 4-Fluoro-benzenesulfo- 25 mg S H N CD O 3 nic acid 2-methoxy-D3- 50 mg N O carbonylamino-3H- F O 1448346-27-7 benzoimidazol-5-yl ester

O H Luxabendazole BI054 O N 4-Fluoro-benzenesulfo- 50 mg S H N CH O 3 nic acid 2-methoxycarbo- 100 mg N O nylamino-3H-benzoimi- F O 90509-02-7 dazol-5-yl ester

S N Cyclopentylalben- BI017 H (5-Cyclopentanesulfa- 50 mg N CH 3 dazole nyl-1H-benzoimidazol-2- N O 100 mg H yl)-carbamic acid methyl O 77723-30-9 ester BI018 O Cyclopentylalben- (5-Cyclopentanesulfinyl- 50 mg S H dazole sulfoxide N 1H-benzoimidazol-2-yl)- 100 mg N O CH3 carbamic acid methyl N O ester H 131454-43-8 WITEGA Laboratorien Berlin-Adlershof GmbH page 4 of 87 Anthelmintica / Flukicides BI019 O O Cyclopentylalben- (5-Cyclopentanesulfo- 50 mg dazole sulfone S N nyl-1H-benzoimidazol-2- 100 mg H N CH3 yl)-carbamic acid methyl N O ester H O 1448346-31-3 Oxibendazole-amine- BI032 D D 5-Propoxy-D7-1H- 25 mg D7 D O N benzoimidazol-2-yl- 50 mg D NH amine D D D 2 N H 1448346-35-7 BI023 O N Oxibendazole-amine 5-Propoxy-1H-benzo- 50 mg H C 3 NH hydrochloride 2 imidazol-2-yl-amine 100 mg N hydrochloride H HCl 1538624-34-8 D D Oxibendazole-D7 BI030 O (5-Propoxy-D7-1H- 25 mg D O O N benzoimidazol-2-yl)- 50 mg D N CH3 D D D H carbamic acid methyl N H 1173019-44-7 ester

BI066 O CH3 Oxibendazole (5-Propoxy-1H- 100 mg O N O benzimidazol-2-yl) H3C NH carbamic acid methyl N 20559-55-1 ester H BI071 Febantel N-(2-Methoxy-acetyl- 10 mg

amino-4-phenylsulfanyl- 100 mg N’,N’’-bis-(methoxycarbonyl)-guanidine

58306-30-2

O CH Febantel-D6 BI031 O 3 N-(2-Methoxy-acetyl- 25 mg amino-4-phenylsulfanyl)- S NH 50 mg N’,N”-bis-(methoxy-D - 3 carbonyl)-guanidine NH O D D

D HN N O D D D O O 1173021-79-8 5-Nitrobenzimidazole BI033 O2N N 5-Nitro-1H-benzimi- 50 mg

dazole 100 mg N H 94-52-0

BI039 O O Ciclobendazole (5-Cyclopropanecar- 50 mg N O Cyclobendazole bonyl-1H-benzoimida- 100 mg NH CH zol-2-yl)-carbamic acid 3 N methyl ester H 31431-43-3

BI040 N 4-Hydroxy-tetramisole 4-(2,3,5,6-Tetrahydro- 25 mg HO imidazo[2,1-b]thiazol-6- 50 mg N S yl-phenol 6649-26-9

H Cl BI041 D D Tetramisole-D5 6-Phenyl-D5-2,3,5,6- 25 mg hydrochloride tetrahydro-imidazo[2,1- N 50 mg D b]thiazole hydrochloride

N S 1173021-85-6 D D

WITEGA Laboratorien Berlin-Adlershof GmbH page 5 of 87 Anthelmintica / Flukicides

BI042 N D D Carbendazim-D3 (1H-Benzoimidazol-2-yl)- 50 mg H carbamic acid methyl N D 100 mg ester-D3 N O H 1255507-88-0 O BI043 I Nitroxynil 4-Hydroxy-3-iodo-5-nitro- 50 mg OH benzonitrile 100 mg

NC NO2 1689-89-0 BI044 I Nitroxynil-13C6 4-Hydroxy-3-iodo-5-nitro- 25 mg 13 13C OH benzonitrile- C6 50 mg 13 13 C C 13 13 C C 1325559-31-6 NC 13C NO 2 O BI045 O Rafoxanide N-[3-Chloro-4-(4-chloro- 50 mg I phenoxy)-phenyl]-2- 100 mg N Cl Cl hydroxy-3,5-diiodo- H OH benzamide 22662-39-1 I O BI046 O Rafoxanide-13C6 N-[3-Chloro-4-(4-chloro- 25 mg I 13C phenoxy)-phenyl]-2- 50 mg 13C 13C N Cl Cl H hydroxy-3,5-diiodo- 13C 13C 13 13C OH benzamide- C6 1353867-98-7 I BI047 CN Closantel-13C6 N-{5-Chloro-4-[(4-chloro- 25 mg H3C H O phenyl)-cyano-methyl]-2- 50 mg I 13C methyl-phenyl}-2- 13C 13C N Cl Cl H hydroxy-3,5-diiodo- 13C 13C 13 H 13C OH benzamide- C6 I 1325559-20-3

BI048 CN Closantel N-{5-Chloro-4-[(4-chloro- 50 mg H3C phenyl)-cyano-methyl]-2- O 100 mg methyl-phenyl}-2- I N Cl Cl hydroxy-3,5-diiodo- H OH benzamide 57808-65-8 I BI070 Salantel N-[3-Chloro-4-(4-chloro- 50 mg benzoyl)phenyl]-2-hydro- 100 mg xy-3,5-diiodobenzamide

36093-47-7 BI051 Cl Oxyclozanid-13C6 2,3,5-Trichloro-N-(3,5- 25 mg Cl O dichloro-2-hydroxy- 50 mg Cl 13C phenyl)-6-hydroxy- 13C 13C N Cl 13 H benzamide- C6 OH 13C 13C H 13C OH 1353867-74-9 Cl

WITEGA Laboratorien Berlin-Adlershof GmbH page 6 of 87 Anthelmintica / Flukicides

BI052 H Cl Clorsulon-13C6 4-Amino-6-trichloro- 25 mg 13 H2N C 13 13 ethenyl-1,3-benzene- 50 mg C C CCl2 13 13 C6-disulfonamide C 13C H NO S 13C SO NH 2 2 2 2 1325559-24-7 H BI053 H Niclosamide-13C6 5-Chloro-N-(2-chloro-4- 25 mg H 13 13 C NO2 O 13C 13C hydrate (see Data nitro-phenyl- C6)-2- 50 mg 13 13 Cl C C Sheet) hydroxy-benzamide N 13C H H hydrate (see Data Sheet) Cl OH x mole H O 2 1325808-64-7 BI065 CN Monepantel-D5 N-[1-Cyano-2-(5-cyano- 5 mg S 2-trifluoromethyl phen- CF3 10 mg D D H oxy)-1-methylethyl-D ]-4- N 5 O trifluoromethylsulfanyl D3C CN O - CF3 benzamide BI056 CN Monepantel N-[1-Cyano-2-(5-cyano- 50 mg S 2-trifluoromethyl- CF 100 mg H 3 phenoxy)-1-methyl- N O ethyl]-4-trifluoromethyl- H C CN 851976-50-6 sulfanyl-benzamide CF3 3 O BI068 CN O Monepantel sulfoxide- N-[1-Cyano-2-(5-cyano- 5 mg S D5 2-trifluoromethyl phen- CF 10 mg D D H 3 oxy)-1-methylethyl-D ]- N 5 O 4-trifluoromethanesulfinyl

D3C CN CF3 O benzamide - BI057 CN O Monepantel sulfoxide N-[1-Cyano-2-(5-cyano- 50 mg S 2-trifluoromethyl- CF 100 mg H 3 phenoxy)-1-methyl- N O ethyl]-4-trifluoromethane- NC CH 851976-72-2 sufinyl-benzamide CF3 3 O BI069 CN O O Monepantel sulfone- N-[1-Cyano-2-(5-cyano- 5 mg S D5 2-trifluoromethyl phen- CF3 10 mg D D H N oxy)-1-methylethyl-D5]-4- O trifluoromethanesulfonyl D3C CN O - CF3 benzamide CN BI058 O O Monepantel sulfone N-[1-Cyano-2-(5-cyano- 50 mg S 2-trifluoromethyl- CF 100 mg H 3 phenoxy)-1-methyl- N O ethyl]-4-trifluoromethane- H C CN 851976-52-8 sulfonyl-benzamide CF3 3 O BI061 Praziquantel-D11 2-(Cyclohexyl-D -carbo- 25 mg O D D 11 nyl)-1,2,3,6,7,11b-hexa- D 50 mg N hydro-pyrazino[2,1a]iso- D D N D D quinolin-4-one D D O D D 1246343-36-1

BI062 O CD3 Parbendazole-D3 (5-Butyl-1H-benzoimi- 50 mg N O H3C dazol-2-yl)-carbamic acid 100 mg NH methyl-D ester N 1613439-58-9 3 H

WITEGA Laboratorien Berlin-Adlershof GmbH page 7 of 87 beta-Agonists Order Formula Name Chemical Name Offer No. CAS Number BA001 OH Brombuterol 1-(4-Amino-3,5-dibromo- 50 mg H Br N hydrochloride phenyl)-2-tert- 100 mg butylamino-ethanol hydrochloride Cl H2N H 21912-49-2 Br BA019 OH Brombuterol 1-(4-Amino-3,5-dibromo- 50 mg H Br N phenyl)-2-tert- 100 mg butylamino-ethanol

H2N Br 41937-02-4

BA028 NH2 Brombuterol-D9 1-(4-Amino-3,5-dibromo- 25 mg Br Br hydrochloride phenyl)-2-tert-butyl-D9- 50 mg amino-ethanol

hydrochloride H Cl H N CD3 HO CD3 1353867-94-3 CD3

BA029 NH2 Brombuterol-D9 1-(4-Amino-3,5-dibromo- 10 mg Br Br phenyl)-2-tert-butyl-D9- 25 mg amino-ethanol

H N CD3 HO CD3 1353940-55-2 CD3

BA068 NH2 Bromchlorbuterol-D9 1-(4-Amino-3-bromo-5- 10 mg Cl Br hydrochloride chloro phenyl)-2-(tert- 25 mg butyl-D9-amino) ethanol HCl hydrochloride H N CD3 HO CD3 - CD3 BA002 OH Bromchlorbuterol 1-(4-Amino-3-bromo-5- 50 mg H Br N hydrochloride chloro-phenyl)-2-tert- 100 mg butylamino-ethanol hydrochloride Cl H2N H 78982-84-0 Cl

BA021 NH2 Cimaterol-D7 2-Amino-5-(1-hydroxy-2- 25 mg CN isopropyl-D7-amino- 50 mg ethyl)-benzonitrile

D H D N HO D D D D 1228182-44-2 D

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BA016 NH2 Cimaterol 2-Amino-5-(1-hydroxy-2- 50 mg CN isopropylamino-ethyl)- 100 mg benzonitrile

H N HO 54239-37-1

BA023 NH2 Cimbuterol-D9 2-Amino-5-(2-tert-butyl- 10 mg CN amino-D9-1-hydroxy- 25 mg ethyl)-benzonitrile 50 mg

H N CD3 HO CD3 1246819-04-4 CD3 BA003 OH Cimbuterol 2-Amino-5-(2-tert-butyl- 50 mg H NC N amino-1-hydroxy-ethyl)- 100 mg benzonitrile

H N 2 54239-39-3

BA066 NH2 Clenbuterol 1-(4-Amino-3,5-dichloro 50 mg Cl Cl hydrochloride phenyl)-2-tert-butyl- 100 mg amino-ethanol HCl hydrochloride

H N CH3 HO CH 3 21898-19-1 CH3

BA038 NH2 Clenbuterol-D6-HCl 1-(4-Amino-3,5-dichloro- 25 mg Cl Cl phenyl)-2-tert-butyl-D6- 50 mg amino-ethanol hydro- H Cl chloride

H N CD3 HO CH3 - CD3 BA025 Cl Clenbuterol-D9 1-(4-Amino-3,5-dichloro- 10 mg

H2N phenyl)-2-tert-butyl-D9- CD3 25 mg CD amino-ethanol 3 50 mg Cl N CD 3 129138-58-5 OH H BA008 OH Clenbuterol-D9 1-(4-Amino-3.5-dichloro- 25 mg H phenyl)-2-tert-butyl-D9- Cl N CD3 hydrochloride 50 mg CD amino-ethanol hydro- 3 chloride Cl CD3 H2N H Cl 184006-60-8 BA010 OH Clencyclohexerol 4-[2-(4-Amino-3,5- 50 mg H Cl N hydrochloride dichloro-phenyl)-2- 100 mg hydroxy-ethylamino]- Cl H N H OH cyclohexanol 2 1435934-75-0 hydrochloride Cl

WITEGA Laboratorien Berlin-Adlershof GmbH page 9 of 87 beta-Agonists

OH BA011 H Clenhexerol 1-(4-Amino-3,5-dichloro- 50 mg Cl N hydrochloride phenyl)-2-hexylamino- 100 mg ethanol hydrochloride Cl H2N H Cl - OH BA015 H Clenhexerol 1-(4-Amino-3,5-dichloro- 50 mg Cl N phenyl)-2-hexylamino- 100 mg ethanol

H2N Cl 78982-88-4

BA062 NH2 Clenisohexerol 1-(4-Amino-3,5-dichloro- 50 mg Cl Cl hydrochloride phenyl)-2-(1,1-dimethyl- 100 mg HCl butylamino)-ethanol hydrochloride H N CH3 HO 37158-48-8 H3C CH3 NH BA014 2 Clenisopenterol 1-(4-Amino-3,5-dichloro- 50 mg Cl Cl hydrochloride phenyl)-2-(3-methyl- 100 mg H Cl butylamino)-ethanol hydrochloride H N HO 1435935-00-4

BA067 NH2 Clenisopenterol-D7 1-(4-Amino-3,5-dichloro- 10 mg Cl Cl hydrochloride phenyl)-2-(2-isopropyl- 25 mg HCl D -ethylamino) ethanol 7 hydrochloride H N CD3 HO D 1794752-28-5 CD3

BA027 NH2 Clenpenterol-D11 1-(4-Amino-3,5-dichloro- 25 mg Cl Cl hydrochloride phenyl)-2-(1,1-dimethyl- 50 mg propyl-D -amino)- 11 ethanol hydrochloride D D H H Cl N HO CD3 D3C CD3 1325559-11-2

BA033 NH2 Clenpenterol-D5 1-(4-Amino-3,5-dichloro- 10 mg Cl Cl hydrochloride phenyl)-2-(1,1-dimethyl- 25 mg propyl-D -amino)-ethanol 5 D D hydrochloride H H Cl N HO CD 3 1794793-20-6

BA013 NH2 Clenpenterol 1-(4-Amino-3,5-dichloro- 50 mg Cl Cl hydrochloride phenyl)-2-(1,1-dimethyl- 100 mg propylamino)-ethanol H Cl hydrochloride H N HO 37158-47-7

BA004 OH Clenproperol 1-(4-Amino-3,5-dichloro- 50 mg H Cl N phenyl)-2- 100 mg isopropylamino-ethanol

H2N Cl 38339-11-6

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BA018 OH Clenproperol-D7 1-(4-Amino-3,5-dichloro- 25 mg H Cl N CD phenyl)-2-isopropyl-D7- 50 mg 3 amino-ethanol D 100 mg CD3 H2N Cl 1173021-09-4 BA005 OH Clenproperol 1-(4-Amino-3,5-dichloro- 50 mg H Cl N hydrochloride phenyl)-2- 100 mg isopropylamino-ethanol hydrochloride H N Cl 2 H 75136-83-3 Cl

BA059 NH2 Hydroxymethylclen- 2-[2-(4-Amino-3,5- 25 mg Cl Cl buterol-D6 hydrochlo- dichloro-phenyl)-2- 50 mg ride hydroxy-ethylamino]-2-

H Cl methyl-propan-1-ol-D6 hydrochloride H N CD3 HO - CD3 OH BA037 OH OH Hydroxymethylclen- 2-[2-(4-Amino-3,5- 50 mg H Cl N buterol hydrochloride dichloro-phenyl)-2- 100 mg hydroxy-ethylamino]-2- methyl-propan-1-ol H N 2 H Cl hydrochloride 37162-89-3 Cl

BA024 NH2 Mabuterol-D9 1-(4-Amino-3-chloro-5- 10 mg Cl CF3 hydrochloride trifluoromethyl-phenyl)-2- 25 mg tert-butyl-D -amino- 9 50 mg H Cl ethanol hydrochloride H N CD3 HO CD3 CD3 1353867-83-0 BA012 OH Mabuterol 1-(4-Amino-3-chloro-5- 50 mg H Cl N hydrochloride trifluoromethyl-phenyl)-2- 100 mg tert-butylamino-ethanol Cl H N H hydrochloride 2 54240-36-7 CF 3

BA026 NH2 Mapenterol-D11 1-(4-Amino-3-chloro-5- 25 mg Cl CF3 hydrochloride trifluoromethyl-phenyl)-2- 50 mg H Cl (1,1-dimethyl-D6-propyl- D5-amino)-ethanol D D H hydrochloride N HO CD3 1325559-18-9 D3C CD3 BA006 OH Mapenterol 1-(4-Amino-3-chloro-5- 50 mg H F C N hydrochloride trifluoromethyl-phenyl)-2- 100 mg 3 (1,1-dimethyl-

propylamino)-ethanol Cl H2N H hydrochloride 54238-51-6 Cl

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BA022 Tulobuterol-D9 2-tert-Butylamino-D9-1- 10 mg H Cl hydrochloride (2-chlorophenyl)-ethanol 25 mg Cl hydrochloride H N CD3 HO CD3 1325559-14-5 CD3 BA009 Cl OH Tulobuterol 2-tert-Butylamino-1-(2- 50 mg H N hydrochloride chlorophenyl)-ethanol 100 mg hydrochloride

Cl H 56776-01-3 BA030 Clorprenaline-D7 1-(2-Chloro-phenyl)-2- 10 mg isopropyl-D7-amino- 25 mg Cl D ethanol H D 50 mg N HO D D D - D D BA020 Clorprenaline 1-(2-Chloro-phenyl)-2- 50 mg isopropylamino-ethanol 100 mg Cl H N CH3 HO 3811-25-4 CH3

BA034 CH3 Bambuterol-D9 Dimethyl-carbamic acid 10 mg N O hydrochloride 3-(2-tert-butylamino-D - H C OH 9 25 mg 3 H 1-hydroxy-ethyl)-5-dime- O N CD 3 thylcarbamoyloxy-phenyl CD 3 ester hydrochloride CD3 CH3 N O H Cl H3C O 1794810-59-5

BA031 CH3 CH3 Bambuterol Dimethyl-carbamic acid 50 mg N O O N hydrochloride 3-(2-tert-butylamino-1- 100 mg H C CH 3 3 hydroxy-ethyl)-5-dime-

O O thylcarbamoyloxy-phenyl

H ester hydrochloride N CH HO 3 CH CH 3 3 81732-46-9 H Cl

HO O CH3 OH BA032 CH3 (R,R)-Formoterol N-[2-Hydroxy-5-[(1R)-1- 50 mg COOH OHC 1 3 N N 1' HOOC 2 H H tartrate hydroxy-2-[[(1’R)-2’-(4- OH OH 100 mg methoxyphenyl)-1’- (1R,1'R) (2R,3R) (Arformoterol tartrate) methylethyl]amino]ethyl]

phenyl]-formamide (2R,3R)-2,3-dihydroxy- 200815-49-2 butanedioate

O2N BA035 OH “Phenylethanolamine 1-(4-Methoxy-phenyl)-2- 20 mg H N A” [1-methyl-3-(4-nitro- 50 mg phenyl)-propylamino]- O ethanol 1346746-81-3

O2N BA036 OH “Phenylethanolamine 1-(4-Methoxy-D3-phe- 20 mg H N D A-D3” nyl)-2-[1-methyl-3-(4- 50 mg D nitro-phenyl)-propyl- O D - amino]-ethanol WITEGA Laboratorien Berlin-Adlershof GmbH page 12 of 87 beta-Agonists BA039 OH OH Pirbuterol acetate 6-(2-tert-Butylamino-1- 50 mg hydroxy-ethyl)-2-hydro- 100 mg xymethyl-pyridin-3-ol CH COOH N 3 acetate H N CH3 HO CH3 65652-44-0 CH3

BA040 OH OH Pirbuterol-D9 acetate 6-(2-tert-Butyl-D9-amino- 10 mg 1-hydroxy-ethyl)-2-hy- 25 mg droxymethyl-pyridin-3-ol CH COOH N 3 acetate

NH CD HO 3 CD3 1431291-46-1 CD3 BA041 OH Colterol acetate 4-(2-tert-Butylamino-1- 50 mg OH hydroxy-ethyl)-benzene- 100 mg 1,2-diol acetate CH3COOH

H N CH3 HO CH3 10255-14-8 CH3

BA043 OH Colterol-D9 acetate 4-(2-tert-Butyl-D9-amino- 10 mg OH 1-hydroxy-ethyl)-ben- 25 mg zene-1,2-diol acetate CH3COOH

H N CD3 HO CD3 1420043-63-5 CD3 BA060 OH Deterenol acetate 4-(1-Hydroxy-2-isopro- 25 mg (Paraproterenol ace- pylamino-ethyl)-phenol 50 mg CH3COOH tate; N-Isopropyloctop- acetate H amine acetate) N CH3 HO CH3 1644449-83-1 BA069 OH Buctopamine 4-(2-tert-Butylamino-1- 10 mg hydrochloride hydroxyethyl) phenol 25 mg HCl (Salbutamol impurity B hydrochloride hydrochloride, tert.- H Butylnorsynephrine N CH3 HO hydrochloride) CH 3 CH3

112337-52-7 BA070 OH Mebuctopamine 4-(2-tert.-Butylamino-1- 10 mg O hydrochloride hydroxyethyl)-2-meth- 25 mg CH3 (3-O-Methyl Colterol oxyphenol hydrochloride HCl hydrochloride) H N CH3 HO CH3 CH 3 93309-94-5

WITEGA Laboratorien Berlin-Adlershof GmbH page 13 of 87 beta-Agonists BA042 OH Salbutamol acetate 2-(tert-Butylamino)-1-(4- 50 mg (Albuterol acetate) hydroxy-3-hydroxy- 100 mg OH methylphenyl)ethanol

CH3COOH acetate H N CH3 HO 1420043-41-9 H3C CH3 OH BA044 Salbutamol-D9 acetate 2-(tert-Butyl-D9-amino)- 10 mg (Albuterol-D9 acetate) 1-(4-hydroxy-3-hydroxy- 25 mg OH methylphenyl)ethanol

CH3COOH acetate

H N CD3 HO 1781417-68-2 D3C CD3 BA073 OH Salbutamol (Albuterol) 2-(tert-Butylamino)-1-(4- 50 mg hydroxy-3-hydroxymethyl OH 100 mg phenyl)ethanol

H N CH3 HO CH3 18559-94-9 CH3 BA049 OH Salmeterol xinafoate N-(2-Hydroxy-2-(4- 10 mg O OH N hydroxy-3-(hydroxyme- H 25 mg OH OH O thyl)phenyl)ethyl)-6-(4- phenylbutoxy)hexan-1- OH aminium 1-hydroxy-2- 94749-08-3 naphthoate BA050 OH Salmeterol-13C6 xinafo- N-(2-Hydroxy-2-(4- 10 mg 13C 13 13 O OH C C N OH O H ate 13C 13C OH hydroxy-3-(hydroxyme- 13 25 mg C OH thyl)phenyl)ethyl)-6-(4- 13 phenyl- C6-butoxy)- - hexan-1-ammonium 1- hydroxy-2-naphthoate BA045 HO OH Orciprenaline acetate 5-(1-Hydroxy-2-isopro- 50 mg CH COOH 3 hydrate (see Data Sheet) pylamino-ethyl)-benze- 100 mg Metaproterenol acetate ne-1,3-diol acetate H N CH3 x mole H2O hydrate (see Data Sheet) hydrate (see Data Sheet) HO - CH3 BA046 Orciprenaline-D7 acetate 5-(1-Hydroxy-2-isopro- 10 mg hydrate (see Data Sheet) HO OH pyl-D7-amino-ethyl)- 25 mg CH3COOH Metaproterenol-D7 benzene-1,3-diol acetate acetate hydrate (see hydrate (see Data Sheet) H x mole H2O Data Sheet) N CD3 HO D CD3 -

BA047 HO OH Terbutaline acetate 5-(2-tert-Butylamino-1- 50 mg CH3COOH hydrate (see Data Sheet) hydroxy-ethyl)-benzene- 100 mg 1,3-diol acetate hydrate H N CH3 x mole H O (see Data Sheet) HO 2 H3C CH3 -

WITEGA Laboratorien Berlin-Adlershof GmbH page 14 of 87 beta-Agonists

HO OH BA048 Terbutaline-D9 acetate 5-(2-tert-Butyl-D9-amino- 10 mg hydrate (see Data Sheet) CH3COOH 1-hydroxy-ethyl)-benze- 25 mg H ne-1,3-diol acetate N CD3 x mole H2O hydrate (see Data Sheet) HO D3C CD3 -

BA051 OH Ractopamine hydrochlo- 4-{3-[2-Hydroxy-2-(4- 50 mg HCl ride hydroxyphenyl)ethylamin 100 mg o]butyl}phenol hydro- OH chloride (mixture of H diastereomers) N 90274-24-1 HO CH3 BA074 Ractopamine acetate 4-{3-[2-Hydroxy-2-(4- 10 mg hydroxyphenyl)ethylamin 25 mg o]butyl}phenol acetate (mixture of diastereomers)

BA075 Ractopamine-D6 acetate 4-{3-[2-Hydroxy-2-(4- 10 mg hydroxyphenyl)ethylamin 25 mg o]butyl-2,2,3,4,4,4- D }phenol acetate 6 (mixture of - diastereomers)

BA077 Ritodrine-D3 hydrochlo- (1RS,2SR)-1-(4- 10 mg ride Hydroxyphenyl)-2-[2-(4- 25 mg hydroxyphenyl) - ethylamino]propan-1-ol- D3 hydrochloride (mixture of enantiomers) BA076 Ritodrine hydrochloride (1RS,2SR)-1-(4- 10 mg Hydroxyphenyl)-2-[2-(4- hydroxyphenyl) 23239-51-2 ethylamino]propan-1-ol hydrochloride (mixture of enantiomers) OH BA052 H Fenoterol hydrobromide (RR,SS)-5-{1-Hydroxy-2- 50 mg HO N [2-(4-hydroxy-phenyl)-1- 100 mg methyl-ethylamino]- CH3 OH ethyl}-benzene-1,3-diol OH hydrobromide (mixture of H Br enantiomers)

OH H HO N 1944-12-3 CH3 OH OH H Br

WITEGA Laboratorien Berlin-Adlershof GmbH page 15 of 87 beta-Agonists

OH BA071 H Fenoterol acetate 5-{1-Hydroxy-2-[2’-(4- 10 mg HO N hydroxy phenyl)-1’- CH3COOH 25 mg CH3 methyl ethylamino]ethyl} OH benzene-1,3-diol acetate OH (mixture of - diastereomers)

OH D D BA072 H D Fenoterol-D6 acetate 5-{1-Hydroxy-2-[2’-(4- 10 mg HO N CH3COOH hydroxy phenyl)-1’- 25 mg CD3 OH methyl-ethyl-D6-amino] OH ethyl}-benzene-1,3-diol acetate (mixture of - diastereomers)

BA053 OH erythro-Isoxsuprine (1RS,2SR,1'SR)-1-(p- 50 mg H hydrochloride N Hydroxyphenyl)-2-(1'- 100 mg O methyl-2'-phenoxyethyl- CH3 CH3 HO amino)-1-propanol hydrochloride (mixture of H Cl enantiomers)

OH H N O

CH3 CH3 HO 579-56-6 H Cl

H alloerythro-Isoxsuprine- BA055 H 13 (1RS,2SR,1'RS)-1-(p- 10 mg C H 13C 13C 13C6 hydrochloride Hydroxyphenyl)-2-(1'- OH H 25 mg 13 13 13 N C C methyl-2'-phenoxy- C6- O 13C H ethylamino)-1-propanol CH3 CH3 H HO hydrochloride (mixture of enantiomers) H Cl H H 13 13 C 13 H OH C C H 13 13 N C C O 13C H CH CH H - HO 3 3 H Cl BA065 H Isoxsuprine-13C6 (1RS,2SR,1'SR)-1-(4- 10 mg 13 H C H hydrochloride (mixture of OH 13C 13C Hydroxyphenyl)-2-(1'- 25 mg H erythro- and alloerythro- 13 13 13 methyl-2'-phenoxy- C6- 2 N 1' C C 1 O 13C H diastereomers) ethylamino)-1-propanol CH3 CH3 H HO hydrochloride and (1RS,2SR,1'RS)-1-(4- HCl Hydroxyphenyl)-2-(1'- (1RS, 2SR, 1'SR) 13 "erythro" methyl-2'-phenoxy- C6- ethylamino)-1-propanol

H hydrochloride 13 H C H OH 13C 13C H 13 13 2 N 1' C C 1 O 13C H CH3 CH3 H HO HCl (1RS, 2SR, 1`RS) - "alloerythro"

WITEGA Laboratorien Berlin-Adlershof GmbH page 16 of 87 beta-Agonists

BA056 H3C Zilpaterol hydrochloride (6RS,7RS)-7-Hydroxy-6- 10 mg CH3 [(1-methylethyl)amino]- 25 mg HN 4,5,6,7-tetrahydro-1H- imidazo[4,5,1- HO 6 HCl 7 jk][1]benzazepin-2-one

N hydrochloride (mixture of

O enantiomers) N H (6RS, 7RS) 119520-06-8

BA057 Zilpaterol-13C3 (6RS,7RS)-7-Hydroxy-6- 10 mg hydrochloride 13 [(1-methylethyl- C3)ami- 25 mg no]-4,5,6,7-tetrahydro- 1H-imidazo[4,5,1- jk][1]benzazepin-2-one hydrochloride (mixture of

enantiomers)

1613439-55-6

OH BA061 H Carbuterol-D9 acetate [5-(2-tert-Butyl-D9-amino- 10 mg hydrate (see Data Sheet) N NH2 1-hydroxy-ethyl)-2- 25 mg hydroxy-phenyl]-urea O CH3COOH acetate hydrate (see H x mole H O Data Sheet) N CD3 2 HO

D3C CD3 -

OH BA058 H Carbuterol acetate [5-(2-tert-Butylamino-1- 10 mg hydrate (see Data Sheet) N NH2 hydroxy-ethyl)-2-hydro- 25 mg xy-phenyl]-urea acetate O CH3COOH hydrate (see Data Sheet) H N CH3 x mole H2O HO

H3C CH3 1613439-57-8

BA063 OH Labetalol hydrochloride 2-Hydroxy-5-[1-hydroxy- 100 mg H N 2-[(1-methyl-3-phenyl- 50 mg propyl)amino]ethyl]benz- CH3 amide hydrochloride HO HCl O NH 2 32780-64-6

OH BA064 H Bamethane hemisulfate 4-(2-Butylamino-1-hydro- 100 mg N CH3 xyethyl)phenol hemi- 50 mg sulfate HO 5716-20-1 1/2 H2SO4

WITEGA Laboratorien Berlin-Adlershof GmbH page 17 of 87 Quinolones Order Formula Name Chemical Name Offer No. CAS Number

CH001 O Norfloxacin-D5 1-Ethyl-D5-6-fluoro-4- 25 mg F COOH hydrate (see Data oxo-7-piperazin-1-yl-1,4- 50 mg Sheet) dihydroquinoline-3- x mole H2O 100 mg N N carboxylic acid hydrate D (see Data Sheet) HN D D D D 1015856-57-1 (anhydrous) CH016 O O Ciprofloxacin-D8 1-Cyclopropyl-6-fluoro-4- 50 mg F hydrochloride hydrate oxo-7-piperazin-D8-1-yl- 100 mg OH 1,4-dihydro-quinoline-3- D (see Data Sheet) carboxylic acid D N N HCl hydrochloride hydrate D D x mole H O D N 2 (see Data Sheet) D H D D 1216659-54-9 (anhydrous)

CH003 O Nalidixic acid-D5 1,4-Dihydro-1-ethyl-D5-7- 25 mg COOH methyl-1,8-naphthy- 50 mg ridine-4-one-3-carboxylic 100 mg acid H3C N N D CD D 3 1189467-36-4

CH004 O Pefloxacin-D5 1-Ethyl-D5-6-fluoro-7-(4- 25 mg F COOH methyl-piperazin-1-yl)-4- 50 mg oxo-1,4-dihydro- 100 mg quinoline-3-carboxylic N N acid N D H C CD 1228182-51-1 3 D 3 CH023 O Fleroxacin-D3 6,8-Difluoro-1-(2-fluoro- 25 mg F COOH hydrochloride ethyl)-7-(4-methyl-D3- 50 mg piperazin-1-yl)-4-oxo-

HCl 1,4-dihydro-quinoline-3- N N carboxylic acid N F D3C hydrochloride F - CH005 O Enrofloxacin-D5 1-Cyclopropyl-7-(4-ethyl- 25 mg F COOH hydrochloride D5-piperazin-1-yl)-6- 50 mg fluoro-4-oxo-1,4-dihydro- 100 mg quinoline-3-carboxylic N N HCl D C N acid hydrochloride 3 - D D CH024 O Gatifloxacin-D3 1-Cyclopropyl-6-fluoro-4- 25 mg F COOH hydrochloride oxo-8-methoxy-D3-7-(3- 50 mg methylpiperazin-1-yl)-

H3C 1,4-dihydro-quinoline-3- N N HCl carboxylic acid hydro- HN O - D3C chloride

WITEGA Laboratorien Berlin-Adlershof GmbH page 18 of 87 Quinolones CH027 O Moxifloxacin-D3 1-Cyclopropyl-6-fluoro-8- 10 mg F COOH hydrochloride methoxy-D3-7- 25 mg [(4aS,7aS)-octahydro- H pyrrolo [3,4-b]pyridin-6- N N HCl yl)-4-oxo-1,4- O D3C dihydroquinoline-3- NH H 1092356-42-7 carboxylic acid hydrochloride CH026 O Moxifloxacin 1-Cyclopropyl-6-fluoro-8- 50 mg F COOH hydrochloride methoxy-7-[(4aS,7aS)- octahydropyrrolo H [3,4-b]pyridin-6-yl)-4- N N HCl oxo-1,4- O 151096-09-2 H3C dihydroquinoline-3- NH H carboxylic acid hydrochloride CH006 O O Difloxacin-D3 1-(4-Fluorophenyl)-6- 25 mg F hydrochloride hydrate fluoro-7-(4-methyl-D - OH 3 50 mg (see Data Sheet) piperazin-1-yl)-4-oxo- 100 mg N N HCl 1,4-dihydro-quinoline-3- D N carboxylic acid

D x mole H2O hydrochloride hydrate D 1173021-89-0 (see Data Sheet) (anhydrous) F

CH007 O Miloxacin-D3 5-Methoxy-D3-8-oxo-5,8- 25 mg COOH dihydro-[1,3]dioxolo[4,5- 50 mg g]quinoline-7-carboxylic O 100 mg acid N O CD3 1228182-43-1 CH025 Miloxacin 5-Methoxy-8-oxo-5,8- 10 mg dihydro-[1,3]dioxolo[4,5- 25 mg g]quinoline-7-carboxylic

acid

37065-29-5

CH009 O Oxolinic acid-D5 5-Ethyl-D5-8-oxo-5,8- 25 mg O COOH dihydro-[1,3]dioxolo[4,5- 50 mg g]quinoline-7-carboxylic 100 mg O acid N D CD3 D 1189890-98-9

CH022 O Cinoxacin-D5 1-Ethyl-D5-4-oxo-1,4- 25 mg O COOH dihydro-[1,3]dioxolo[4,5- 50 mg g]cinnoline-3-carboxylic N O acid N D D C - 3 D

WITEGA Laboratorien Berlin-Adlershof GmbH page 19 of 87 Quinolones CH010 O O Sarafloxacin-D8 6-Fluoro-1-(4-fluoro- 25 mg F hydrochloride hydrate phenyl)-4-oxo-7- D D OH 50 mg D (see Data Sheet) piperazine-D8-1-yl-1,4- D N N dihydro-quinoline-3- HCl carboxylic acid HN D D x mole H O hydrochloride hydrate D 2 D (see Data Sheet) - F CH011 O O Enoxacin-D8 hydrate 1-Ethyl-6-fluoro-4-oxo-7- 25 mg F (see Data Sheet) piperazine-D -1-yl-1,4- D D OH 8 50 mg D dihydro- D N N N x mole H2O [1,8]naphthyridine-3- HN D CH carboxylic acid hydrate D 3 1329642-60-5 D D (see Data Sheet) (anhydrous) CH012 O Marbofloxacin 8-Fluoro-3-methyl-9-(4- 50 mg F COOH methyl-piperazin-1-yl)-6- 100 mg oxo-2,3-dihydro-6H-1-

N N oxa-3,3a-diaza- phenalene-5-carboxylic N O N 115550-35-1 acid H3C CH3 CH013 O Ofloxacin-D3 8-Fluoro-3-methyl-9-(4- 25 mg F COOH methyl-D3-piperazin-1- 50 mg yl)-6-oxo-2,3-dihydro-6H-

1-oxa-3a-aza- N N phenalene-5-carboxylic N O 1173147-91-5 acid D3C CH3

CH019 H3C O O Nequinate-D7 7-Benzyloxy-D7-6-butyl- 25 mg CH3 4-oxo-1,4-dihydro- 50 mg O D D D quinoline-3-carboxylic D O N acid methyl ester H D D 1584701-10-9 D CH014 O O Nequinate 7-Benzyloxy-6-butyl-4- 50 mg CH H C O 3 oxo-1,4-dihydro- 100 mg 3 quinoline-3-carboxylic

O N acid methyl ester H 13997-19-8

O O CH015 Decoquinate-D5 6-Decyloxy-7-ethoxy-D5- 50 mg H3C O O CH 3 4-oxo-1,4-dihydro- 100 mg O N D quinoline-3-carboxylic H 1228182-55-5 D3C D acid ethyl ester

CH017 CH3 O O Buquinolate 4-Hydroxy-6,7-diisobut- 25 mg O H C O CH oxy-quinoline-3-carboxyl 50 mg 3 3 acid ethyl ester H3C O N H CH3

5486-03-3

WITEGA Laboratorien Berlin-Adlershof GmbH page 20 of 87 Quinolones CH018 O Danofloxacin-D3 1-Cyclopropyl-6-fluoro-7- 25 mg F COOH (5-methyl-D3-2,5-diaza- 50 mg bicyclo-[2.2.1]hept-2-yl)-

N N 4-oxo-1,4-dihydro-quino- N line-3-carboxylic acid D3C 1217683-55-0

CH020 Flumequine-13C3 9-Fluoro-5-methyl-1-oxo- 10 mg 6,7-dihydro-1H,5H-pyri- 25 mg do[3,2,1-ij] quinoline-2- 13 carboxylic acid- C3

1185049-09-5

CH021 O Lomefloxacin-D5 1-Ethyl-D5-6,8-difluoro-7- 25 mg F COOH hydrochloride (3-methyl-piperazin-1-yl)- 50 mg 4-oxo-1,4-dihydro- H3C HCl quinoline-3-carboxylic N N D acid hydrochloride HN F - D3C D

CH028 Pipemidic acid-D5 8-Ethyl-D5-5-oxo-2- 50 mg hydrochloride (piperazin-1-yl)-5,8- 100 mg dihydro pyrido[2,3- d]pyrimidine-6-carboxylic

acid hydrochloride -

WITEGA Laboratorien Berlin-Adlershof GmbH page 21 of 87 Lactam-Antibiotics Order Formula Name Chemical Name Offer No. CAS Number LA001 COOH O Cefacetrile (6R,7R)-3-(Acetoxy- 50 mg O methyl)-7-(cyanoacet- 100 mg N O CH3 amido)-8-oxo-5-thia-1- O S azabicyclo[4.2.0]oct-2- NC N H 10206-21-0 ene-2-carboxylic acid H LA002 COOH O Cefacetrile-13C3 (6R,7R)-3-(Acetoxy- 10 mg O methyl)-7-(cyanoacet- N O CH3 13 25 mg O amido- C )-8-oxo-5-thia- 3 13C S 13C N 1-azabicyclo[4.2.0]oct-2- 13C H N H - ene-2-carboxylic acid COOH O LA003 N Cefapirin (6R,7R)-3-Acetoxy- 50 mg O methyl-8-oxo-7-(2- N O CH3 100 mg O pyridin-4-ylsulfanyl- S S N H acetylamino)-5-thia-1- H 21593-23-7 aza-bicyclo[4.2.0]oct-2- ene-2-carboxylic acid LA004 Ceftiofur sodium salt (6R,7R)-7-[(2-Aminothia- 50 mg N O H N N H zol-4-yl)((Z)-methoxyimi- 100 mg 2 H N S no)acetamido]-3-(2-furo- S O N S yl thio methyl)-8-oxo-5- O O thia-1-azabicyclo(4.2.0) O O O- Na+ 104010-37-9 oct-2-ene-2-carboxylic acid, sodium salt LA005 Phenoxymethylpeni- (2S,5R,6R)-3,3-dimethyl- 50 mg H cillin potassium salt 7-oxo-6-(2-phenoxy- N H 100 mg S O CH (Penicillin V) acetamido)-4-thia-1- 6 5 3 azabicyclo[3.2.0]heptane O N 2 CH 3 -2-carboxylic acid O COOK potassium salt (2S, 5R, 6R) 132-98-9 LA006 H Phenoxymethylpeni- (2S,5R,6R)-3,3-dimethyl- 10 mg 13 13 H C H cillin-13C6 potassium 7-oxo-6-(2-phenoxy- C6- 13C 13C 25 mg H H salt (Penicillin V – acetamido)-4-thia-1- 13C 13C N 13 S 13C6) azabicyclo[3.2.0]heptane H C O CH 6 5 3 -2-carboxylic acid H O 2 CH N 3 potassium salt O (2S, 5R, 6R) CO2K -

LA007 CH3 Methicillin sodium salt (2S,5R,6R)-6-[(2,6- 10 mg O Dimethoxybenzoyl)amin 25 mg H o]-3,3-dimethyl-7-oxo-4- N H S thia-1-azabicyclo[3.2.0]- 6 5 CH3 heptane-2-carboxylic O O N 2 CH H C 3 acid sodium salt 3 O (2S,5R,6R) CO2Na 132-92-3

LA009 CD3 Methicillin-D6 sodium (2S,5R,6R)-6-[(2,6- 10 mg O salt Dimethoxy-D6- 25 mg H benzoyl)amino]-3,3- H N dimethyl-7-oxo-4-thia-1- S 6 5 CH3 azabicyclo[3.2.0]heptane O O N 2 CH D C 3 -2-carboxylic acid 3 O CO Na - sodium salt (2S,5R,6R) 2

WITEGA Laboratorien Berlin-Adlershof GmbH page 22 of 87 Lactam-Antibiotics LA017 Ampicillin-D5 (2S,5R,6R)-6-([(2R)-2- 5 mg Amino-2-phenyl-D5- 10 mg acetyl]amino)-3,3- 25 mg dimethyl-7-oxo-4-thia-1- azabicyclo[3.2.0]heptane -2-carboxylic acid 1426173-65-0 LA018 Ampicillin (2S,5R,6R)-6-([(2R)-2- 10 mg Amino-2-phenylacetyl]- amino)-3,3-dimethyl-7-

oxo-4-thia-1-azabicyclo[3.2.0]heptane-2- 69-53-4 carboxylic acid LA013 Nafcillin-D5 sodium (2S,5R,6R)-6-[(2-Ethoxy- 10 mg salt D5-naphthalene-1- carbonyl)amino]-3,3- dimethyl-7-oxo-4-thia-1-

azabicyclo[3.2.0]heptane -2-carboxylic acid 1356354-25-0 sodium salt

LA008 Nafcillin sodium salt (2S,5R,6R)-6-[(2-Ethoxy- 10 mg naphthalene-1-carbonyl)- amino]-3,3-dimethyl-7- H N H oxo-4-thia-1-azabicy- S clo[3.2.0]heptane-2- 6 5 CH3 O O N 2 CH3 carboxylic acid sodium O salt CH3 CO2Na (2S, 5R, 6R) 985-16-0 LA010 COOH O Cefalotin (6R,7R)-3-[(Acetyl- 50 mg O oxy)methyl]-8-oxo-7-[[2- N O CH3 100 mg O (2-thienyl)acetyl]amino]- S N H 5-thia-1-azabicy- S H clo[4.2.0]oct-2-ene-2- 153-61-7 carboxylic acid LA011 Pheneticillin (2S,5R,6R)-3,3- 10 mg CH3 H potassium salt Dimethyl-7-oxo-6-(2- N H 25 mg S phenoxypropanamido)-4- O CH 6 5 3 thia-1-azabicy- O N 2 CH3 clo[3.2.0]heptane-2- O (2S, 5R, 6R) CO2K carboxylic acid 132-93-4 potassium salt LA012 Desacetylcefapirin (6R,7R)-3- 10 mg sodium salt Hydroxymethyl-8-oxo-7- [(4-pyridinylthio)acetyl]amino-5-thia-1-aza-

bicyclo[4.2.0]oct-2-ene- 2-carboxylic acid sodium 104557-24-6 salt

WITEGA Laboratorien Berlin-Adlershof GmbH page 23 of 87 Lactam-Antibiotics LA014 Oxacillin sodium salt (2S,5R,6R)-3,3- 10 mg Dimethyl-6-[(5-methyl-3- phenyl-isoxazol-4-

yl)amido]-7-oxo-4-thia-1- azabicyclo[3.2.0]heptane 1173-88-2 -2-carboxylic acid sodium salt

LA015 Oxacillin-13C6 sodium (2S,5R,6R)-3,3- 10 mg salt Dimethyl-6-[(5-methyl-3- 13 25 mg phenyl- C6-1,2-oxazol- 4-yl)amido]-7-oxo-4-thia-

1-azabicyclo[3.2.0]heptane-2-carboxylic acid - sodium salt

LA016 Cloxacillin benzathine Bis{(2S,5R,6R)-6-[[3-(2- 50 mg Chlorophenyl)-5-methyl- 1,2-oxazole-4-

carbonyl]amino]-3,3- dimethyl-7-oxo-4-thia-1- 23736-58-5 azabicyclo[3.2.0]heptane -2-carboxylic acid}-N,N'- dibenzyl ethane-1,2- diamine salt LA019 Cloxacillin benzathine Imp 1 TFA Cloxacillin benzathine 2-{1-[3-(2-Chlorophenyl)- 10 mg 10 mg (for further information, Imp 1 TFA 5-methyl-1,2-oxazol-4-yl see data sheet) amido]-2-[benzyl(2- benzylaminoethyl)amino]

-2-oxo ethyl}-5,5- dimethyl-1,3-thiazolidin- - 4-carboxylic acid bis (trifluoroacetic acid) salt

WITEGA Laboratorien Berlin-Adlershof GmbH page 24 of 87 Mycotoxins Order Formula Name Chemical Name Offer No. CAS Number

MT001 OH O CH3 Zearalenone (E)-(7S)-2,4-Dihydroxy- 10 mg 7-methyl-7,8,9,10,13,14- 25 mg O 7 hexahydro-12H-6-oxa-

benzocyclotetradecene- HO O 17924-92-4 5,11-dione

OH O CH3 MT013 HO Zearalenone-14-O-β- (3S)-16-Hydroxy-3- 10 mg 3 13C O glucoside-13C6 methyl-3,4,5,6,7,8,9,10- 13C O 25 mg HO 13C 13C 14 octahydro-1H-2- HO 13C 13C O O HO benzoxacyclotetradecine - -1,7-dione-14-O-β-D- 13 glucopyranoside- C6

MT011 OH O CH3 Zearalenone-14-O-β- (3S)-16-Hydroxy-3- 10 mg OH O 3 glucoside methyl-3,4,5,6,7,8,9,10- O 25 mg HO HO O 14 O octahydro-1H-2- OH benzoxacyclotetradecine

-1,7-dione-14-O-β-D- 105088-14-0 glucopyranoside

MT002 OH O CH3 Zearalanone (7S)-2,4-Dihydroxy-7- 10 mg methyl- 25 mg O 7 7,8,9,10,13,14,15,16-

octahydro-12H-6-oxa- HO O 5975-78-0 benzocyclotetradecene- 5,11-dione

MT003 OH O CH3 α-Zearalenol (E)-(7S,11R)-2,4,11- 10 mg Trihydroxy-7-methyl- 25 mg O 7 7,8,9,10,11,12,13,14-

11 octahydro-6-oxa- HO OH 36455-72-8 benzocyclotetradecen-5- one

MT004 OH O CH3 α-Zearalenol-D5 (E)-(7S,11R)-2,4,11- 10 mg D Trihydroxy-7-methyl- 25 mg O 7 D 7,8,9,10,11,12,13,14-

11 D octahydro- HO - OH 10,10,11,12,12-D5-6- D D oxa-benzocyclotetradecen-5-one

MT005 OH O CH3 β-Zearalenol (E)-(7S,11S)-2,4,11- 10 mg Trihydroxy-7-methyl- 25 mg O 7 7,8,9,10,11,12,13,14-

11 octahydro-6-oxa- HO OH 71030-11-0 benzocyclotetradecen-5- one

MT006 OH O CH3 β-Zearalenol-D5 (E)-(7S,11S)-2,4,11- 10 mg D Trihydroxy-7-methyl- 25 mg O 7 D 7,8,9,10,11,12,13,14-

11 D octahydro- HO - OH 10,10,11,12,12-D5-6- D D oxa-benzocyclotetradecen-5-one

MT007 OH O CH3 Zeranol (α-Zearalanol) (7S,11R)-2,4,11-Trihy- 10 mg droxy-7-methyl-7,8,9,10, 25 mg O 7 11,12,13,14,15,16-deca-

11 hydro-6-oxa-benzocyclo- HO OH 26538-44-3 tetradecen-5-one

WITEGA Laboratorien Berlin-Adlershof GmbH page 25 of 87 Mycotoxins

MT008 OH O CH3 Zeranol-D5 (α-Zearala- (7S,11R)-2,4,11- 10 mg D nol-D5) Trihydroxy-7-methyl- 25 mg O 7 D 7,8,9,10,11,12,13,14,15, 11 D 16-decahydro- HO OH 10,10,11,12,12-D5-6- D D - oxa-benzocyclotetradecen-5-one

MT009 OH O CH3 Taleranol (β-Zearala- (7S,11S)-2,4,11- 10 mg nol) Trihydroxy-7-methyl- 25 mg O 7 7,8,9,10,11,12,13,14,15, 11 16-decahydro-6-oxa- 42422-68-4 HO OH benzocyclotetradecen-5- one

MT010 OH O CH3 Taleranol-D5 (β-Zea- (7S,11S)-2,4,11- 10 mg D ralanol-D5) Trihydroxy-7-methyl- 25 mg O 7 D 7,8,9,10,11,12,13,14,15, 11 D 16-decahydro- HO OH 10,10,11,12,12-D5-6- D D - oxa-benzocyclotetradecen-5-one MT012 OH O Alternariol 3,7,9-Trihydroxy-1- 10 mg methyl-6H-dibenzo- O [b,d]pyran-6-one

HO 641-38-3 H C OH 3

WITEGA Laboratorien Berlin-Adlershof GmbH page 26 of 87

Nitrofuran Metabolites Order Formula Name Chemical Name Offer No. CAS Number NF001 O AHD 1-Amino-imidazolidin- 50 mg 2,4-dione H N 100 mg 2 N NH 250 mg 6301-02-6 O NF002 O AHD-13C3 1-Amino-imidazolidin- 10 mg 13 13 2,4-dione-[2,4,5- C3] H N C 25 mg 2 N NH

13C 13C H 957509-31-8 H O NF023 O AHD hydrochloride 1-Amino-imidazolidin- 100 mg 2,4-dione H N 1-Aminohydantoin 2 N NH HCl hydrochloride

O 2827-56-7 NF003 AMOZ 3-Amino-5-morpholin-4- 50 mg O N ylmethyl-oxazolidin-2- 100 mg one 250 mg O N NH2 O 43056-63-9

NF004 D D AMOZ-D5 3-Amino-5-morpholin-4- 50 mg O N D ylmethyl-oxazolidin-2- 100 mg one-D D D 5 250 mg O N NH2 1017793-94-0 O NF005 O AOZ 3-Amino-oxazolidin-2- 50 mg one NH 100 mg O N 2 250 mg 80-65-9 NF006 O AOZ-D4 3-Amino-oxazolidin-2- 10 mg one-D4 NH 25 mg O N 2 50 mg D D 1188331-23-8 D D NF008 H Cl SCA-HCl – 13C,15N2 Semicarbazide 10 mg O 13 15 13 hydrochloride- C, N2 C 15 50 mg 15 NH H N N 2 2 1173020-16-0 100 mg H NF022 H O SCA-HCl Semicarbazide 100 mg N C H hydrochloride H N N HCl 563-41-7 H H

WITEGA Laboratorien Berlin-Adlershof GmbH page 27 of 87 Nitrofuran Metabolites NF009 O 2-NP-AHD 1-[(2-Nitro-benzylidene)- 50 mg amino]-imidazolidin-2,4- N 100 mg N NH dione 250 mg

NO 623145-57-3 2 O NF010 O 2-NP-AHD-13C3 1-[(2-Nitro-benzylidene)- 10 mg 13C amino]-imidazolidin-2,4- N 13 25 mg N NH dione-[2,4,5- C ] 3 13C 13C NO H 1007476-86-9 2 H O NF011 O 2-NP-AMOZ 5-Morpholin-4-ylmethyl- 100 mg 3-[(2-nitro-benzylidene)- N 250 mg O N amino]-oxazolidin-2-one 1 g

O N NO2 183193-59-1 NF012 O 2-NP-AMOZ-D5 5-Morpholin-4-ylmethyl- 10 mg 3-[(2-nitro-benzylidene)- N 25 mg O N amino]-oxazolidin-2-one- D D D5 O N D NO2 D D 1173097-59-0 NF013 O 2-NP-AOZ 3-[(2-Nitro-benzylidene)- 100 mg amino]-oxazolidin-2-one N 250 mg O N 1 g

NO 19687-73-1 2 NF014 O 2-NP-AOZ-D4 3-[(2-Nitro-benzylidene)- 10 mg amino]-oxazolidin-2-one- N 25 mg O N D 4

D D NO 1007478-57-0 D D 2 NF015 O 2-NP-SCA 2-Nitro-benzaldehyde- 100 mg semicarbazone N 250 mg H N N 2 H 1 g NO 16004-43-6 2 NF016 O 2-NP-SCA-13C,15N2 2-Nitro-benzaldehyde- 10 mg 13 13 15 C 15 semicarbazone-[ C, N2] 15 N 25 mg H N N 2 H NO 957509-32-9 2 NF017 O 4-NP-SCA 4-Nitro-benzaldehyde- 100 mg

NO2 semicarbazone N 250 mg H N N 2 H 5315-87-7 1 g

NF007 D D Furaltadone-D5 5-morpholin-4-ylmethyl- 25 mg O N D 3-(5-nitro-furan-2- 50 mg D D ylmethyleneamino)- 100 mg O N oxazolidin-2-one-D5 N O O NO 2 1015855-64-7

WITEGA Laboratorien Berlin-Adlershof GmbH page 28 of 87 Nitrofuran Metabolites NF018 O Furazolidone-D4 3-[(5-Nitro-furan-2- 10 mg N ylmethylene)-amino]- N O 25 mg O N oxazolidin-2-one-D 2 O 4 50 mg D D D D 1217222-76-8 NF019 O Nitrofurazone- 5-Nitro-furan-2-carbal- 25 mg 13 15N C 13C,15N2 dehyde semicarbazone- 15 NH 15 13 50 mg O N N 2 1,2- N , C 2 O 2 H 1217220-85-3 NF020 O Nitrofurantoin-13C3 1-[(5-Nitro-furan-2- 25 mg 13 ylmethylene)-amino]- N C 50 mg N NH imidazolidine- O N 2 O 13 13 13 C C 2,4-dione- C3 H 1217226-46-4 H O

NF021 O Dantrolene-13C3 1-{[1-[5-(4-Nitrophenyl)- 10 mg 13C furan-2-yl]-methylidene]- N 25 mg N NH amino}-imidazolidine- O 13C 13C 13 2,4-dione-[2,4,5- C3] O2N H H O -

NF038 Nifuraldezone-15N3 5-Nitro-2-furaldehyde 10 mg 15 semioxamazone- N3 25 mg - NF024 Nifuraldezone 5-Nitro-2-furaldehyde 10 mg semioxamazone 3270-71-1

NF034 Nifuroxazide-13C6 5-Nitro-2-furaldehyde p- 10 mg 13 hydroxybenzoyl- C6- 25 mg hydrazone

NF025 Nifuroxazide 5-Nitro-2-furaldehyde p- 10 mg hydroxybenzoylhydra- zone 965-52-6 NF033 4-Hydroxybenzhydra- 4-Hydroxybenzhydra- 10 mg 13 zide-13C6 zide- C6 25 mg

- NF031 2-NP-4-Hydroxybenz- 2-Nitrobenzaldehyde p- 10 mg hydrazide hydroxybenzoylhydra- zone 304459-18-5

NF039 Aminoguanidine- Hydrazine carboximid- 10 mg 13 15 13C,15N4 sulfate amide- C, N4 hemisulfate

WITEGA Laboratorien Berlin-Adlershof GmbH page 29 of 87 Nitrofuran Metabolites NF040 Aminoguanidine- Hydrazine carboximid- 10 mg 13 15 13C,15N2 sulfate amide- C, N2 hemisulfate

- NF026 Nitrovin hydrochloride 2-[[(1E,4E)-1,5-Bis(5- 10 mg nitrofuran-2-yl)penta-1,4- dien-3-ylidene]amino]

guanidine hydrochloride 2315-20-0

NF032 2-NP-Aminoguanidine 2-[(2-Nitrophenyl)methy- 10 mg lene] hydrazinecarbox- imidamide 102632-31-5

NF027 Nifursol 5-Nitro-2-furaldehyde o- 10 mg hydroxy-3,5-dinitroben- zoylhydrazone

16915-70-1

NF030 Nifursol-13C6 5-Nitro-2-furaldehyde o- 10 mg hydroxy-3,5-dinitroben- 25 mg zoyl-13C -hydrazone 6 -

NF028 DNSAH 3,5-Dinitrosalicylic acid 50 mg hydrazide

955-07-7

NF035 2-NP-DNSAH 3,5-Dinitrosalicylic acid 10 mg (2-nitrobenzyliden)hydrazide

851368-01-9 NF029 DNSAH-13C6 3,5-Dinitrosalicylic acid- 10 mg 13 C6 hydrazide 25 mg

NF036 Oxamic acid hydrazide 2-Hydrazino-2-oxoacet- 10 mg (Oxamic hydrazide) amide

515-96-8 NF037 Oxamic acid hydrazi- 2-Hydrazino-2-oxoacet- 10 mg 15 de-15N3 (Oxamic hy- amide- N3 15 25 mg drazide- N3)

WITEGA Laboratorien Berlin-Adlershof GmbH page 30 of 87

Nitroimidazoles Order Formula Name Chemical Name Offer No. CAS Number

NM001 N Dimetridazole-D3 1-Methyl-D3-2-methyl-5- 50 mg nitro-1H-imidazole O N 100 mg 2 N 64678-69-9 250 mg CD 3 NM023 N Dimetridazole 1,2-Dimethyl-5-nitro-1H- 100 mg imidazole CH O2N N 3 551-92-8 CH3 NM002 N HMMNI 2-Hydroxymethyl-1- 50 mg OH methyl-5-nitro-1H- O N 100 mg 2 N imidazole 936-05-0 250 mg

NM003 N HMMNI-D3 2-Hydroxymethyl-1- 25 mg OH methyl-D3-5-nitro-1H- O N 50 mg 2 N imidazole 100 mg CD3 1015855-78-3 250 mg NM004 N Ipronidazole 2-Isopropyl-1-methyl-5- 50 mg nitro-1H-imidazole O N 100 mg 2 N 14885-29-1 250 mg

NM005 N Ipronidazole-D3 2-Isopropyl-1-methyl-D3- 50 mg 5-nitro-1H-imidazole O N 100 mg 2 N 1015855-83-0 250 mg CD 3 NM006 N Ipronidazole-OH 2-(1-Methyl-5-nitro-1H- 50 mg imidazol-2-yl)-propan-2- O N IPZOH 100 mg 2 N OH ol

35175-14-5

NM007 N Ipronidazole-OH-D3 2-(1-Methyl-D3-5-nitro- 25 mg 1H-imidazol-2-yl)- O N IPZOH–D3 50 mg 2 N OH propan-2-ol 100 mg CD3 1156508-86-9

NM014 15N Metronidazole- 1-(2-Hydroxyethyl)-2- 25 mg 13 13C 13C2,15N2 methyl- C-5-nitro- O N 15 13 13 15 50 mg 2 N C H 3 imidazole-2- C-1,3- N2 HO 1173020-03-5 1-(2-Hydroxyethyl)-2- NM013 N D Metronidazole-OH-D2 25 mg hydroxymethyl-D2-5- O N D MNZOH-D2 50 mg 2 N nitroimidazole OH

- OH

WITEGA Laboratorien Berlin-Adlershof GmbH page 31 of 87 Nitroimidazoles NM008 N Metronidazole-OH 1-(2-Hydroxyethyl)-2- 50 mg hydroxymethyl-5- O N MNZOH 100 mg 2 N nitroimidazole OH

OH 4812-40-2 Ronidazole 2-Carbamoyloxymethyl- NM009 N O 25 mg O 1-methyl-5-nitro-1H- O N 50 mg 2 N imidazole NH 2 7681-76-7

Ronidazole-D3 2-Carbamoyloxymethyl- NM010 N O 25 mg O 1-methyl-D3-5-nitro-1H- O N 50 mg 2 N imidazole NH 2 100 mg CD 1015855-87-4 3 NM011 N Ternidazole 3-(2-Methyl-5-nitro- 50 mg hydrochloride imidazol-1-yl)-propan-1- O N 100 mg 2 N ol hydrochlorid 250 mg

HCl 70028-95-4 HO NM012 N Carnidazole [2-(2-Methyl-5-nitro- 25 mg

O N imidazol-1-yl)-ethyl]- 50 mg 2 N thiocarbamic acid O- 100 mg methyl ester

HN O S 42116-76-7

NM015 NO2 5-Chloro-1-methyl-4- 5-Chloro-1-methyl-4- 50 mg N nitroimidazole nitro-1H-imidazole 100 mg

N Cl 4897-25-0 CH 3 NM016 N Menidazole 2-Methyl-5-nitro-1H- 50 mg imidazole O N CH 100 mg 2 N 3 696-23-1 H NM017 N Tinidazole 1-(2-Ethanesulfonyl- 50 mg ethyl)-2-methyl-5-nitro- O N CH 100 mg 2 N 3 1H-imidazole

O S CH3 19387-91-8 O NM018 N Secnidazole hydrate 1-(2-Methyl-5-nitro- 50 mg (see Data Sheet) imidazol-1-yl)-propan-2- 100 mg O N CH3 2 N x mole H2O ol hydrate (see Data

OH Sheet)

227622-73-3 CH3

WITEGA Laboratorien Berlin-Adlershof GmbH page 32 of 87 Nitroimidazoles NM020 15N Secnidazole-13C2, 1-(2-Methyl-5-nitro- 10 mg 15N2 imidazol-2-13C-1,3-15N - 13C 2 25 mg O2N 13 15 CH 1-yl)-propan-2-ol N 3 OH -

CH3 NM021 15N Ornidazole-13C2, 1-(3-Chlor-2-hydroxypro- 10 mg 13 13 15N2 pyl)-2-methyl- C-5-nitro- C 13 15 25 mg O2N 13CH imidazole-2- C-1,3- N 15N 3 2 OH - Cl NM022 N Nimorazole-D8 4-[2-(5-Nitro imidazol-1- 10 mg yl) ethyl] morpholine-D8 O2N N

D D N D D

D D O - D D NM019 N Nimorazole 4-[2-(5-Nitro-imidazol-1- 50 mg yl)-ethyl]-morpholine O N 100 mg 2 N

N 6506-37-2 O

WITEGA Laboratorien Berlin-Adlershof GmbH page 33 of 87

NSAIDs Order Formula Name Chemical Name Offer No. CAS Number

NS001 CF3 Flunixin-D3 2-(2-Methyl-D3-3- 50 mg trifluoro-methyl- CD3 100 mg phenylamino)-nicotinic

acid NH O

N OH

1015856-60-6 NS002 O O Meloxicam-D3 4-Hydroxy-2-methyl-D3- 50 mg S CD 1,1-dioxo-1,2-dihydro- N 3 100 mg H 16-benzo[e]-[1,2]- N S thiazin-3-carboxylic acid- (5-methyl-thiazol-2-yl)- OH O N 942047-63-4 amide NS049 Tenoxicam-D3 4-Hydroxy-2-methyl-D - 10 mg N O OH 3 1,1-dioxo-1,2-dihydro- 25 mg S 1λ6-thieno[2,3-e][1,2]thia- N H zine-3-carboxylic acid N pyridin-2-ylamide D3C S O O - NS036 Tenoxicam 4-Hydroxy-2-methyl-1,1- 50 mg N O OH 6 dioxo-1,2-dihydro-1λ - 100 mg S thieno[2,3-e][1,2]thiazine N H -3-carboxylic acid N S pyridin-2-ylamide O O 59804-37-4 NS043 HO 5-Hydroxytenoxicam 4-Hydroxy-2-methyl-N- 10 mg N O OH (5-hydroxy-pyridin-2-yl)- 25 mg S N 2H-thieno[2,3-e]-1,2- H N thiazine-3-carboxamide H3C S 1,1-dioxide O O 93739-45-8

NS048 N O OH Piroxicam-D3 4-Hydroxy-2-methyl-D3- 25 mg 1,1-dioxo-1,2-dihydro- 50 mg 1λ6-benzo[e][1,2]thia- N 100 mg H zine-3-carboxylic acid N D3C S pyridin-2-yl-amide O O 942047-64-5 NS045 Piroxicam 4-Hydroxy-2-methyl-1,1- 50 mg N O OH 6 dioxo-1,2-dihydro-1λ - 100 mg N benzo[e][1,2]thiazine-3- H N carboxylic acid pyridin-2- H3C S yl-amide O O 36322-90-4 NS044 HO 5-Hydroxypiroxicam 4-Hydroxy-2-methyl-1,1- 10 mg N O OH 6 dioxo-1,2-dihydro-1λ - 25 mg N benzo[e][1,2]thiazine-3- H N carboxylic acid (5-hydro- H3C S xy-pyridin-2-yl)-amide O O 77459-78-0

WITEGA Laboratorien Berlin-Adlershof GmbH page 34 of 87 NSAIDs

NS038 CF3 5-Hydroxyflunixin-D3 5-Hydroxy-2-(2-methyl- 10 mg D -3-trifluoromethyl- CD3 3 25 mg phenylamino)-nicotinic

acid NH O

N OH

1185088-54-3 OH

NS015 CF3 5-Hydroxyflunixin 5-Hydroxy-2-(2-methyl-3- 10 mg

CH3 trifluoromethyl- 25 mg phenylamino)-nicotinic

acid NH COOH N

75369-61-8 OH O NS051 CH Firocoxib 3-Cyclopropylmethoxy-4- 50 mg S 3 (4-methanesulfonyl- O 100 mg phenyl)-5,5-dimethyl-5H-

furan-2-one

CH O 3

CH3 O 189954-96-9 O O NS003 CH Firocoxib-D6 3-Cyclopropylmethoxy-4- 50 mg S 3 O (4-methanesulfonyl- 100 mg phenyl)-5,5-dimethyl-D - 6 5H-furan-2-one

CD O 3 CD O 3 O 1353853-37-8 NS052 O Rofecoxib 4-(4-Methanesulfonyl- 50 mg O phenyl)-3-phenyl-5H- H3C S 100 mg furan-2-one

162011-90-7 O O NS035 O O Etoricoxib 5-Chloro-3-(4-methane- 50 mg S sulfonyl-phenyl)-6’- CH 100 mg 3 methyl-[2,3’]bipyridinyl Cl

N 202409-33-4 N CH 3

WITEGA Laboratorien Berlin-Adlershof GmbH page 35 of 87 NSAIDs

NS033 F3C 2,5-Dimethyl-celecoxib 4-[5-(2,5-Dimethyl- 100 mg H3C DMC phenyl)-3-trifluormethyl- N 1H-pyrazole-1-yl] N benzensulfonamide

CH 3 457639-26-8 SO NH 2 2 NS047 O O Deracoxib 4-[3-Difluoromethyl-5-(3- 50 mg S F fluoro-4-methoxy- H2N N 100 mg N phenyl)-pyrazol-1- F yl]benzenesulfonamide

H C 169590-41-4 3 O F NS046 O O Deracoxib-D3 4-[3-Difluoromethyl-5-(3- 50 mg S F fluoro-4-methoxy-D3- H2N N 100 mg N phenyl)-pyrazol-1- F yl]benzenesulfonamide

D C - 3 O F

H O NS039 N Parecoxib 4-(5-Methyl-3-phenyl- 50 mg Me S isoxazol-4-yl)-N-propio- 100 mg O O Me nyl-benzenesulfonamide

O N 198470-84-7

H O NS040 N Parecoxib-D3 4-(5-Methyl-D3-3-phenyl- 50 mg H C S 3 isoxazol-4-yl)-N-propio- 100 mg CD O O 3 nyl-benzenesulfonamide

O N -

NS041 O Valdecoxib 4-(5-Methyl-3-phenyl- 50 mg H2N S isoxazol-4-yl)-benzene- 100 mg O CH 3 sulfonamide

O N

181695-72-7 O NS042 H N Valdecoxib-D3 4-(5-Methyl-D3-3-phenyl- 50 mg 2 S isoxazol-4-yl)-benzene- CD 100 mg O 3 sulfonamide

O N

1219794-90-7

WITEGA Laboratorien Berlin-Adlershof GmbH page 36 of 87 NSAIDs O NS004 H2N 4-Aminoantipyrine-D3 4-Amino-1-methyl-5- 50 mg AA-D3 methyl-D3-2-phenyl-1,2- 100 mg dihydro-pyrazol-3-one N D3C N 68229-55-0 CH 3

NS016 H2N O 4-Aminoantipyrine 4-Amino-1,5-dimethyl-2- 50 mg phenyl-1,2-dihydro- 100 mg N pyrazol-3-one H3C N 83-07-8 CH3

NS057 HO O 4-Hydroxyantipyrine- 4-Hydroxy-1-methyl-D3- 50 mg D3 5-methyl-2-phenyl-1,2- 100 mg N dihydro-pyrazol-3-one H3C N 65566-65-6 CD3

NS054 H3C H 4-Acetamidoantipyrine N-(1,5-Dimethyl-3-oxo-2- 50 mg N O phenyl-2,3-dihydro-1H- 100 mg O pyrazol-4-yl)-acetamide N H C 3 N 83-15-8 CH3

NS059 H3C H 4-Acetamidoantipy- N-(1-Methyl-D3-5- 25 mg N O rine-D3 methyl-3-oxo-2-phenyl- 50 mg O 2,3-dihydro-1H-pyrazol- N 4-yl)-acetamide H3C N - CD3

NS058 OHC NH O 4-Formylaminoanti- N-(1-Methyl-D3-5-methyl- 50 mg pyrine-D3 (FAA-D3) 3-oxo-2-phenyl-2,3- 100 mg N dihydro-1H-pyrazol-yl)- H3C N formamide - CD3 NS017 OHC NH O 4-Formylaminoanti- N-(1,5-Dimethyl-3-oxo-2- 50 mg pyrine phenyl-2,3-dihydro-1H- 100 mg N FAA pyrazol-4-yl) formamide H3C N

CH 3 1672-58-8

NS031 Isopropylaminoanti- 4-Isopropyl-D6-amino- 25 mg pyrine-D6 1,5-dimethyl-2-phenyl- 50 mg 1,2-dihydro-pyrazol-3- IPAA-D6 one O N CH Ramifenazon-D6 N 3

D3C

NH CH3 D3C 1330180-51-2 NS005 Isopropylaminoanti- 4-Isopropylamino-1,5- 50 mg pyrine dimethyl-2-phenyl-1,2- 100 mg IPAA dihydro-pyrazol-3-one Ramifenazon O N CH N 3

H3C

N CH3 H C H 3615-24-5 3

WITEGA Laboratorien Berlin-Adlershof GmbH page 37 of 87 NSAIDs

D H NS006 + O 4-Methylaminoantipy- 1,5-Dimethyl-4-methyl- 50 mg D N H O O2N NO2 rine-D3 picrate D3-amino-2-phenyl-1,2- D 100 mg N dihydro-pyrazol-3-one H C 3 N picric acid salt CH NO - 3 2

NS037 D H 4-Methylaminoantipy- 1,5-Dimethyl-4-methyl- 50 mg + N H O - rine-D3 hydrogen D -amino-2-phenyl-1,2- D HSO4 3 100 mg D sulfate dihydro-pyrazol-3-one N hydrogen sulfate H C 3 N - CH 3 NS020 4-Methylaminoantipy- (1,5-Dimethyl-3-oxo-2- 50 mg - H3C NH2 O HSO 4 rine hydrogen sulfate phenyl-2,3-dihydro-H- 100 mg pyrazol-4-yl)-methyl- N H C ammonium; hydrogen 3 N - sulfate CH3 NS007 H 4-Dimethyl-D6- (1,5-Dimethyl-3-oxo-2- 50 mg CD3 O D3C N O O2N NO2 aminoantipyrine- phenyl-2,3-dihydro-1H- 100 mg N picrate pyrazol-4-yl)-dimethyl- H3C N (Aminophenazone-D6 D6-ammonium picrate CH3 NO2 picrate) -

NS019 CH3 4-Dimethylamino- 4-Dimethylamino-1,5- 50 mg H C N O 3 antipyrine dimethyl-2-phenyl-1,2- 100 mg (Aminophenazone) dihydro-pyrazol-3-one N H C 3 N CH 58-15-1 3

NS056 CH3 1,5-Dimethyl-1,2-dihy- 1,5-Dimethyl-1,2-dihy- 50 mg dro-pyrazol-3-one dro-pyrazol-3-one 100 mg N CH3 O N 3201-28-3 H

NS008 CH3 O CH3 AMDOPH 2-(N’-Acetyl-N’-methyl-N- 50 mg H C N N phenyl-hydrazino)-N,N- 100 mg 3 N CH 3 dimethyl-2-oxo-

O O acetamide

519-65-3 NS009 H O Tolfenamic acid-13C6 2-(3-Chloro-2-methyl- 10 mg H 13C 13 13 13 phenylamino)- C - C C OH 6 25 mg benzoic acid 13C 13C H 13C NH

H CH3 1420043-61-3 Cl NS065 Mefenamic acid 2-(2,3-Dimethylphenyl- 10 mg amino) benzoic acid 100 mg

61-68-7

WITEGA Laboratorien Berlin-Adlershof GmbH page 38 of 87 NSAIDs NS025 H O Mefenamic acid-13C6 2-(2,3-Dimethyl-phenyl- 10 mg H 13 13 C amino)- C6-benzoic acid 13C 13C OH 25 mg 13 C 13C H 13C NH

H CH3

CH 1325559-19-0 3 NS026 H O Flufenamic acid-13C6 2-(3-Trifluoromethyl- 10 mg 13 H 13C phenylamino)- C - 13 13 6 25 mg C C OH benzoic acid 13C 13C H 13 C NH H

CF 1325559-30-5 3 NS027 H O Meclofenamic acid- 2-(2,6-Dichloro-3-methyl- 10 mg H 13C 13 13C 13C OH 13C6 phenylamino)- C6- 25 mg 13C 13C benzoic acid H 13C NH Cl H Cl - CH 3 NS028 COOH Niflumic acid-13C6 2-(3-Trifluoromethyl- 10 mg 13 phenyl- C6-amino)- 25 mg N NH nicotinic acid 13 H13 C 13 H C C 13 13 C 13 C H C CF3 1325559-33-8 H NS063 Carprofen 2-(6-Chloro-9H-carbazol- 10 mg 2-yl)-propionic acid 100 mg

53716-49-7

NS010 Cl Carprofen-D3 2-(6-Chloro-9H-carba- 25 mg zol-2-yl)-propionic acid- 50 mg CD3 D 3 N COOH 1173019-42-5 H NS011 D Ketoprofen-D3 2-(3-Benzoyl-phenyl)- 50 mg D D O propionic acid-D3 100 mg COOH 159490-55-8

NS012 H3C COOH Vedaprofen 2-(4-Cyclohexyl- 50 mg naphthalen-1-yl)- 100 mg propionic acid

71109-09-6

WITEGA Laboratorien Berlin-Adlershof GmbH page 39 of 87 NSAIDs NS013 D Vedaprofen-D3 2-(4-Cyclohexyl- 50 mg D COOH naphthalen-1-yl)- 100 mg D propionic acid-D 3

1185054-34-5 CH NS034 3 (±)-Naproxen-D3 2-(6-Methoxy-D3- 25 mg naphthalen-2-yl)- D COOH 50 mg D propionic acid 958293-79-3 D O NS014 Na+ -OOC Cl Diclofenac-13C6-Na [2-(2,6-Dichloro-phenyl- 25 mg 13 H H hydrate (see Data amino)-phenyl- C6] 13C N 50 mg 13C 13C Sheet) acetic acid sodium salt 13 13 C C Cl hydrate (see Data Sheet) H 13C H x mole H2O H 1261393-73-0 (anhydrous) NS018 HOOC Hydroxydiclofenac [2-(2,6-Dichloro-4- 10 mg Cl H hydroxy-phenylamino)- 25 mg N phenyl] acetic acid 100 mg 64118-84-9 Cl OH NS032 OH 1-Hydroxyibuprofen 2-[4-(1-Hydroxy-2- 25 mg methyl-propyl)-phenyl]- CH3 50 mg O propionic acid

CH HO 3 CH 53949-53-4 3

NS021 H3C 2-Hydroxyibuprofen 2-[4-(2-Hydroxy-2- 25 mg HO methyl-propyl)-phenyl]- 50 mg CH3 COOH propionic acid

CH 3 51146-55-5

NS029 HO 3-Hydroxyibuprofen 2-[4-(3-Hydroxy-2- 25 mg methyl-propyl)-phenyl]- CH COOH 50 mg 3 propionic acid

CH 3 53949-54-5 NS022 HOOC Carboxyibuprofen 3-[4-(1-Carboxy-ethyl)- 25 mg phenyl]-2-methyl- CH COOH 50 mg 3 propionic acid

CH 3 15935-54-3 NS064 Phenylbutazone 4-Butyl-1,2-diphenyl- 10 mg pyrazolidine-3,5-dione 100 mg

50-33-9

WITEGA Laboratorien Berlin-Adlershof GmbH page 40 of 87 NSAIDs

NS030 CH3 Phenylbutazone- 4-Butyl-1,2-diphenyl- 25 mg 13 13C12 C12-pyrazolidine-3,5- 50 mg dione O O H H H 13C N N 13C H 13C 13C 13C 13C 13C 13C 13C 13C H 13C H H 13C H H H 1325559-13-4 CH NS024 3 Oxyphenbutazone- 4-Butyl-1-(4-hydroxy- 25 mg 13 13C6 phenyl)-2-phenyl- C6- 50 mg O O pyrazolidine-3,5-dione

N N H 13C 13C 13 H 13C C H 13 13 C C - H H HO

NS050 O Paracetamol-D3 4-Acetyl-D3-aminophenol 50 mg CD3 100 mg HO NH 60902-28-5 NS053 H Paracetamol glucuro- 1-O-(4-Acetamido- 25 mg N CH3 K OOC O nide potassium salt phenyl)-β-D-glucopyra- 50 mg HO O HO O nuronic acid potassium OH salt - NS060 Ibuprofen-D3 2-(4-Isobutyl phenyl)- 10 mg 3,3,3-trideutero propionic 25 mg acid 121662-14-4

NS061 Flurbiprofen-D3 2-(2-Fluoro biphenyl-4- 50 mg yl)-3,3,3-trideutero 100 mg propionic acid 1185133-81-6

NS062 Fenbufen-D9 4-(Biphenyl-4-yl-D9)-4- 10 mg oxobutanoic acid 25 mg

1189940-96-2

WITEGA Laboratorien Berlin-Adlershof GmbH page 41 of 87

Pesticides Order Formula Name Chemical Name Offer No. CAS Number PS025 O O Fensulfothion-PO-sul- Diethyl-(4-methylsulfonyl 20 mg S fone phenyl) phosphate H3C O O CH3 P O O CH3 6132-17-8 PS187 Fensulfothion-sulfone O,O’-Diethyl-O’’-[4- 20 mg (methylsulfonyl)phenyl] phosphorothioate

14255-72-2 PS026 O O Fenthion-sulfone O,O-Dimethyl-O-(3- 20 mg S methyl-4-methylsulfonyl H3C S O phenyl) thiophosphate P CH3 H3C O O CH3 3761-42-0 PS027 O Fenthion-sulfoxide O,O-Dimethyl-O-(3- 20 mg S methyl-4-methylsulfinyl H3C S phenyl) thiophosphate O P CH3 H C O 3 O H3C 3761-41-9 PS136 O Fenthion-oxon Dimethyl-(3-methyl-4- 20 mg O CH3 H3C P methylthio phenyl) phos- O O CH3 phate S H3C 6552-12-1 PS078 O Fenthion-oxon-sulf- Dimethyl-(3-methyl-4- 20 mg O CH3 H3C P oxide methylsulfinyl phenyl) O O CH3 phosphate H C S 3 O 6552-13-2 PS079 O Fenthion-oxon-sulfone Dimethyl-(3-methyl-4- 20 mg O CH3 H3C P methylsulfonyl phenyl) O O O phosphate S H3C CH O 3 14086-35-2 PS087 O Fensulfothion-oxon Diethyl-(4-methylsulfinyl 20 mg S O phenyl) phosphate O CH3 H3C P O O 6552-21-2 CH3 PS188 Propaphos O,O’-Dipropyl-O’’-(4- 20 mg methylthiophenyl) phosphate

7292-16-2

WITEGA Laboratorien Berlin-Adlershof GmbH page 42 of 87 Pesticides

PS117 D CD3 Parathion-D10 O,O’-Diethyl-D10-O’’-(4- 20 mg NO nitrophenyl) thiophos- D 2 phate S O P O O D 350820-04-1 D D3C PS041 O Malaoxon S-(1,2-Diethoxy carbo- 20 mg nyl)ethyl-O,O’-dimethyl O O CH3 thiophosphate H3C O P O CH3 S H3C O O 1634-78-2

PS068 O D D Malathion-D10 S-[1,2-Bis(ethoxycarbo- 20 mg nyl-D5)ethyl]-O,O’-dime- S O CD3 thyl dithiophosphate H3C O P O CD3 S H3C O 347841-48-9 O D D

PS086 O Malathion diacid-D6 2-(Dimethoxy-D6-thio- 20 mg phosphoryl sulfanyl) S OH D3C O succinic acid P OH S D3C O O 1346601-20-4 PS085 O Malathion diacid Dimethoxy thiophospho- 20 mg rylsulfanyl-succinic acid S OH H C O 3 P OH S H3C O O 1190-28-9 PS100 O O Chlorthiophos-sulfone O-(2,5-Dichloro-4-me- 20 mg S Cl thylsulfonylphenyl)-O,O- H3C S O CH3 diethyl thiophosphate P Cl O O CH 3 25900-20-3 PS101 O Chlorthiophos- O-(2,5-Dichloro-4-me- 20 mg S Cl sulfoxide thylsulfinyl phenyl)-O,O- H3C S diethyl thiophosphate O CH3 P Cl O O CH3 29185-21-5 PS097 O O Acephate-D3 O,S-Dimethyl-N-acetyl- 20 mg O CH3 P D3-phosphoramido- D C N S CH thioate 3 3 H -

PS170 H3C O O Isofenphos-oxon 2-{[Ethoxy-(propan-2-yl- 20 mg O CH3 (Oxyisofenphos) amino)phosphoryl]oxy}b CH3 O P enzoic acid propan-2-yl N CH3 ester O H 31120-85-1 H3C

WITEGA Laboratorien Berlin-Adlershof GmbH page 43 of 87 Pesticides PS195 Butamifos O-Ethyl-O’-(2-nitro-5- 20 mg methylphenyl)-N-but-2-yl phosphoramidothioate

36335-67-8

PS172 Fenamiphos-sulfoxide Ethyl (3-methyl-4-methyl- 20 mg sulfinyl phenyl) isopro- pylphosphoramidat

31972-43-7

PS171 Fenamiphos-sulfone Ethyl (3-methyl-4-methyl- 20 mg sulfonyl phenyl) isopro- pylphosphoramidat

31972-44-8

PS153 H3C O Heptenophos 7-Chlorobicyclo[3.2.0]- 20 mg O P O hepta-2,6-dien-6-yl dimethyl phosphate O H3C 23560-59-0 Cl

PS081 CH3 2-Diethylamino-6-hy- 2-Diethylamino-4-hydro- 20 mg droxy-4-methylpyrimi- xy-6-methylpyrimidine N dine (DEAMPY)

HO N N CH3 (Metabolite of Pirimiphos-methyl) CH3 42487-72-9

PS092 CH3 2-Diethylamino-D10-6- 2-Diethylamino-D10-4- 20 mg hydroxy-4-methylpyri- hydroxy-6-methyl pyrimi- N D D midine (DEAMPY- dine D10) HO N N CD3 D (Metabolite of Pirimi- CD3 phos-methyl) D

PS084 CH3 Pirimiphos-methyl-D6 O-(2-Diethylamino-6- 20 mg D3C methyl pyrimidin-4-yl)- N O’,O’’-dimethyl-D - S O 6 P thiophosphate O O N N CH3 CD 3 CH 3 -

PS133 D D O Ethephon-D4 2-Chloroethyl-D4-phos- 20 mg OH P phonic acid Cl OH

D D 1020719-29-2

PS071 CH3 Trifloxystrobin acid (E)-2-Methoxyimino-2- 20 mg

O CF3 (CGA 321113) [(E)-1-(3-trifluoromethyl- N phenyl) ethylidenamino- O oxymethyl] phenylacetic H3C N COOH 252913-85-2 acid

WITEGA Laboratorien Berlin-Adlershof GmbH page 44 of 87 Pesticides 15 PS143 CF3 15N Fipronil-13C4,15N2 5-Amino- N-1-(2,6- 10 mg O S 13C dichloro-4-trifluoromethyl 13 13 phenyl)-4-trifluormethyl C C sulfinyl-1H-pyrazole- 13C N H 15N 13 2 N C3-3-carbonitrile- 13C,15N Cl Cl

- CF3

PS142 CF3 N Fipronil 5-Amino-1-(2,6-dichloro- 20 mg O S 4-trifluoromethyl phenyl)- 4-trifluormethyl sulfinyl-

N H N 1H-pyrazole-3- 2 N carbonitrile Cl Cl

120068-37-3 CF3 PS168 Fipronil-sulfone 5-Amino-1-(2,6-dichloro- 20 mg 4-trifluoromethyl phenyl)- 4-trifluoromethylsulfonyl-

1H-pyrazole-3- carbonitrile

120068-36-2

PS072 CF3 N Fipronil-sulfide 5-Amino-1-(2,6-dichloro- 20 mg S 4-trifluoromethyl phenyl)- 4-trifluoromethylsulfanyl-

N 1H-pyrazole-3- H N 2 N carbonitrile Cl Cl

120067-83-6 CF3

PS073 CF3 O Fipronil-carboxamide 5-Amino-1-(2,6-dichloro- 20 mg S O NH2 4-trifluoromethyl phenyl)- 4-trifluoromethane-

N sulfinyl-1H-pyrazole-3- H N 2 N carboxylic acid amide Cl Cl

205650-69-7 CF3 PS183 Fipronil-desulfinyl 5-Amino-1-(2,6-dichloro- 20 mg 4-trifluoromethyl phenyl)- 4-trifluoromethyl-1H-

pyrazole-3-carbonitrile

205650-65-3

WITEGA Laboratorien Berlin-Adlershof GmbH page 45 of 87 Pesticides PS165 Pyriprole 1-[2,6-Dichloro-4- 20 mg (trifluoromethyl)phenyl]- 4-[(difluoromethyl)thio]-5-

[(pyridine-2- ylmethyl)amino]-1H- pyrazole-3-carbonitrile

394730-71-3

PS091 CF3 O 4-(Trifluoromethyl)- 4-(Trifluoromethyl) pyri- 20 mg nicotinic acid (TFNA) dine-3-carboxylic acid OH (metabolite of flonic- amid) N 158063-66-2

PS095 CF3 O 4-(Trifluoromethyl)- N-(4-Trifluoromethyl pyri- 20 mg OH nicotinoyl glycine dine-3-yl carbonyl) N (TFNG) glycine H O N 207502-65-6

PS119 CH3 (E)-Metominostrobin (E)-2-Methoxyimino-N- 20 mg HN methyl-2-(2-phenoxy CH3 N phenyl) acetamide O O O 133408-50-1

PS107 H3C CH3 (Z)-Metominostrobin (Z)-2-Methoxyimino-N- 20 mg O HN methyl-2-(2-phenoxy N phenyl) acetamide O O 133408-51-2

PS177 Pyrametostrobin N-[2-((1,4-Dimethyl-3- 20 mg phenyl-1H-pyrazol-5- yl)oxymethyl)-phenyl]-N-

methoxycarbamic acid methyl ester 915410-70-7 PS179 Pyraclostrobin N-[2-((1-(4-Chlorphenyl)- 20 mg 1H-pyrazol-3-yl)oxymethyl)phenyl]-N-methoxy

carbamic acid methyl ester

175013-18-0 PS118 O Spiromesifen 4-Hydroxy-3-(2,4,6-tri- 20 mg O CH3 Metabolite M01 methyl phenyl)-1-oxa spiro[4.4]non-3-en-2-one OH 148476-30-6 H3C CH3

WITEGA Laboratorien Berlin-Adlershof GmbH page 46 of 87 Pesticides PS125 O O Dicamba-methylester 3,6-Dichloro-2-methoxy- 20 mg H C 3 benzoesäure methyl- Cl O ester CH3

Cl 6597-78-0 PS126 Cl O Dicamba-D3 3,6-Dichloro-2-methoxy- 20 mg D3-benzoic acid OH

CD3 O Cl 349553-95-3

PS094 D D Imazalil-D5 1-[2-Allyloxy-D5-2-(2,4- 20 mg dichloro phenyl) ethyl]- D 1H-imidazole D D O N N Cl

Cl 1398065-91-2 PS128 Cl t-Butylhydroxy-tebuco- 5-(4-Chloro-phenyl)-2,2- 20 mg H3C CH3 nazol dimethyl-3-[1,2,4]triazol- OH 1-yl-methyl]-pentane-1,3- diol OH N N N 212267-64-6

PS075 D O Cl Cl Folpet-D4 N-(Trichloromethyl- 20 mg D Cl thio)phthalimide-D4 N S D - D O PS110 D D O Captan-D6 2-Trichloromethyl-sulfa- 20 mg D nyl-3a,4,7,7a-tetrahydro- N S isoindole-1,3-dione-D6 Cl D Cl D D O Cl 1330190-00-5

PS043 CCl3 Methoxychlor-D14 1,1,1-Trichloro-2,2-bis(4- 20 mg D D methoxy phenyl-D7) D D ethane

D3C CD3 O DD O D D -

PS044 D D DDT-D8 1,1,1-Trichloro-2,2-bis- 20 mg Cl D D Cl (4-chloro phenyl-D4) ethane

D D D D CCl3 -

WITEGA Laboratorien Berlin-Adlershof GmbH page 47 of 87 Pesticides

PS007 Cl Atrazine-D5 6-Chlor-N-ethyl-D5-N'- 20 mg isopropyl-[1,3,5]triazine- CH3 N N D 2,4-diamine D H3C N N N CD3 163165-75-1 H H

PS139 Cl Atrazine-desisopropyl- 6-Chloro-N-ethyl-D5- 20 mg D5 1,3,5-triazine-2,4-dia- N N D D mine H2N N N CD3 1189961-78-1 H PS135 Cl Atrazine-D7 6-Chloro-N-ethyl-N'-iso- 20 mg propyl-D7-[1,3,5]triazine- CD3 N N 2,4-diamin D D3C N N N CH3 - H H

PS 140 Cl Atrazine-desethyl-D7 6-Chloro-N-isopropyl-D7- 20 mg 1,3,5-triazine-2,4-diamin N N CD3 D H2N N N CD3 H 1216649-31-8 PS047 Cl Trietazine-D5 2-Chloro-4-diethylamino- 20 mg 6-ethyl-D5-amino-1,3,5- N N D triazine D H3C N N N CD3 H H3C 1397243-73-0

PS048 Cl Propazine-D7 2-Chloro-4-(isopropyl-D7- 20 mg amino)-6-(isopropyl- CH3 N N CD3 amino)-1,3,5-triazine D H3C N N N CD3 - H H PS056 Cl Simazine-D10 6-Chloro-N,N'-diethyl- 20 mg D10-1,3,5-triazine-2,4- D N N D diamine D D D3C N N N CD3 220621-39-6 H H

PS049 H3C Secbumeton-D5 2-(sec-Butylamino)-4- 20 mg O (ethyl-D5-amino)-6-meth- CH3 N N D oxy-1,3,5-triazine D H3C N N N CD3 - H H

PS050 H3C Prometryn-D7 2-(Isopropyl-D -amino)- 20 mg S 7 4-(isopropylamino)-6- methylthio-1,3,5-triazine CH3 N N CD3 D

H3C N N N CD3 H H - H PS070 H Cyprodinil-13C6 (4-Cyclopropyl-6-methyl- 20 mg H 13C N N pyrimidin-2-yl)phenyl- 13C 13C 13 C6-amine 13C 13C N H 13C H H CH3 1773496-63-1

WITEGA Laboratorien Berlin-Adlershof GmbH page 48 of 87 Pesticides

PS080 D D D D Trifluralin-D14 N,N-Di(n-propyl-D7)-2,6- 20 mg D3C CD3 dinitro-4-trifluoromethyl- N aniline D D D D O N NO 2 2

347841-79-6 CF3 PS042 D DEET-D10 N,N-(Diethyl-D )-3-me- 20 mg D CD 10 3 thyl benzamide D O N D

CD3

CH3 1215576-01-4 PS053 H D D Triforine-D8 N,N'-(2,2,2,2',2',2'-Hexa- 20 mg D D NH CCl3 chloro-1,1'-piperazin-D8- O N N O 1,4-diyl-diethyl)-bis-

Cl3C HN formamide D D 948595-12-8 D D H PS055 Nabam-D4 hydrate (2-Dithiocarboxyamino- 20 mg (see Data Sheet) ethyl-D4)-dithiocarbamic acid disodium salt

hydrate (see Data Sheet) x mole H2O - PS157 EBDC-Dimethyl Dimethyl-N,N’-ethylene- 20 mg bis(dithiocarbamate) 20721-48-6

PS158 EBDC-Dimethyl-D6 Dimethyl-D6-N,N’-ethy- 20 mg lenebis(dithiocarbamate) -

S PS162 H PBDC-Dimethyl Dimethyl-N,N’-propy- 20 mg S N CH3 lenebis(dithiocarbamate) H3C N S H 80555-60-8 S CH3 S PS163 H PBDC-Dimethyl-D6 Dimethyl-D6-N,N’-propy- 20 mg S N CD3 lenebis(dithiocarbamate) D3C N S H - S CH3

PS062 NaDMDTC-D6 Dimethyl-D6-dithiocarb- 20 mg dihydrate (see Data amic acid sodium salt Sheet) hydrate (see Data Sheet) - x mole H2O

PS059 O CD3 Bentazon-D7 3-Isopropyl-D7-2,2-dioxo- 20 mg D 2,3-dihydro-1H-26- N CD 3 benzo[1,2,6]thiadiazin-4- S O N one O H 131842-77-8

WITEGA Laboratorien Berlin-Adlershof GmbH page 49 of 87 Pesticides

PS104 O Metsulfuron-methyl-D3 2-[[(4-Methoxy-D3-6- 20 mg CH3 methyl-1,3,5-triazin-2-yl)- O H aminocarbonyl]aminosul- NH N N O S CD fonyl]benzoic acid methyl 3 ester O O O N N

CH3 - PS089 I- Monoquat iodide 1-Methyl-4-(pyrid-4- 20 mg yl)pyridinium iodide H3C N+ N 38873-01-7

PS090 Monoquat-D3 iodide 1-Methyl-D3-4-(pyrid-4- 20 mg D3C N+ N - yl)pyridinium iodide I 22884-38-4 PS093 Paraquat-D6 diiodide 4,4´-Bipyridinium-1,1´- 20 mg D3C N+ N+ CD3 dimethyl-D -diiodide - 6 I - I - PS098 O Paraquat monopyri- 1,1´-Dimethyl-2´-oxo- 20 mg I done iodide 1´,2´-dihydro-[4,4´] H3C N N CH3 bipyridinyl-1-ium iodide

35022-71-0 O PS099 I Paraquat monopyri- 1-Methyl-D3-1’-methyl-2’- 20 mg done-D3 iodide oxo-1´,2´-dihydro- H3C N N CD3 [4,4’]bipyridinyl-1-ium iodide - PS102 O Paraquat dipyridone 1,1´-Dimethyl-4,4´-bipy- 20 mg ridyl-2,2´-dione H C N N CH 3 3 O 35022-68-5

PS103 O Paraquat dipyridone- 1,1´-Dimethyl-D6-4,4´-bi- 20 mg D6 pyridyl-2,2´-dione D3C N N CD3 - O PS010 O Desmethyl-formamido- 2-Methylformamido-5,6- 20 mg pirimicarb dimethylpyrimidin-4-yl H3C N H dimethylcarbamate

N N O

CH3 H3C O N CH3 CH3 27218-04-8

PS011 H3C Desmethyl-pirimicarb Dimethyl carbamic acid- 20 mg NH 5,6-dimethyl-2-methyl- amino pyrimidin-4-yl N N O ester CH3 H3C O N 30614-22-3 CH3 CH3

WITEGA Laboratorien Berlin-Adlershof GmbH page 50 of 87 Pesticides

PS054 CH3 Pirimicarb-D6 Dimethyl-D6-carbamic 20 mg H3C acid (2-dimethylamino- N 5,6-dimethyl pyrimidin-4-

CH3 yl) ester O N N CD3 CH3 O N CD3 1015854-66-6

PS058 CH3 Carbofuran-D3 2,2-Dimethyl-7-methyl- 20 mg D3-carbamoyloxy-2,3- O CH3 dihydro-benzofuran H N O D3C 1007459-98-4 O PS151 Carbofuran 2,3-Dihydro-2,2-dime- 20 mg CH3 CH thyl-7-benzofuranol N- O 3 methylcarbamate H N O H3C O 1563-66-2 PS152 OH Carbofuran-3-hydroxy (2,2-Dimethyl-3-hydroxy- 20 mg

CH3 2,3-dihydro-7-benzofuranol) N-methyl carbamate O CH3 H N O H3C 16655-82-6 O PS115 O Ethofumesate-2-keto Methansulfonic acid-3,3- 20 mg O H3C O dimethyl-2-oxo-2,3-dihy- S dro-benzofuran-5-yl O O CH3 ester H3C 26244-33-7 PS156 Ethofumesate-D5 Methansulfonic acid-3,3- 20 mg dimethyl-2-ethoxy-D5- 2,3-dihydro-benzofuran-

5-yl 160858-11-7

PS112 O CD3 Isoproturon-D6 N’-(4-Isopropylphenyl)- 20 mg H3C N N,N-dimethyl-D6-urea NH CD3 1007461-76-8 H3C PS051 O Monuron-D6 N-(4-Chlorophenyl)- 20 mg CD3 N’,N’-di(methyl-D3) urea HN N

CD3

Cl 217488-65-8 CD PS052 H 3 Diuron-D6 N-(3,4-Dichlorphenyl)- 20 mg N N N‘,N‘-di(methyl-(D3) urea CD3 O Cl Cl 1007536-67-5

WITEGA Laboratorien Berlin-Adlershof GmbH page 51 of 87 Pesticides PS196 Dymron N-(4-Methylphenyl)-N'- 20 mg (1-methyl-1- phenylethyl)urea

42609-52-9

PS149 H H Thidiazuron 1-Phenyl-3-[1,2,3]thiadi- 20 mg N N S azol-5-yl-urea N O 51707-55-2 N PS150 H Thidiazuron-13C6 1-Phenyl-13C -3- 20 mg H H 6 H 13C N N S [1,2,3]thiadiazol-5-yl- 13C 13C urea N 13 13 C C O N H 13C H H -

PS064 O Carbaryl-D3 1-Naphthol-N-methyl-D3- 20 mg CD3 carbamate O N H

1433961-56-8

PS069 O O Phenmedipham-D3 3-Methoxy-D3-carbonyl- 20 mg CD3 aminophenyl-N-(3-me- H3C N O N O thylphenyl) carbamate H H -

PS077 CD3 Linuron-D6 N'-(3,4-Dichlorophenyl)- 20 mg O H N-methoxy-D3-N-methyl- N N D -urea CD3 3 O Cl Cl 1219804-76-8 PS181 Chloromethiuron N-(4-Chloro-2-methyl- 20 mg phenyl)-N’,N’-dimethyl thiourea

28217-97-2 PS182 Chloromethiuron-D6 N-(4-Chloro-2-methyl- 20 mg phenyl)-N’,N’-dimethyl- D - thiourea 6 -

PS012 N Desnitro imidacloprid 1-(2-Chloropyridin-5-yl- 20 mg HCl hydrochloride methyl)-2-iminoimida- NH zolidine hydrochloride Cl N HN 127202-53-3 PS176 Desnitro-olefin imida- 1-(6-Chloropyridin-3-yl 20 mg cloprid methyl)-1H-imidazol-2-yl 187022-17-9 amin D PS074 D Imidacloprid-D4 1-(6-Chloro pyridin-3-yl 20 mg D N methyl)-2-nitroamino- 4,5-dihydro-1H-imidazol- N D Cl N D4 HN NO2 1015855-75-0

WITEGA Laboratorien Berlin-Adlershof GmbH page 52 of 87 Pesticides

PS082 N Imidacloprid-olefin 1-[(6-Chloropyridin-3- 20 mg yl)methyl]-N-nitro-1H- N imidazol-2-amine Cl N HN NO2 115086-54-9 PS180 4,5-Dihydroxyimida- 1-[(6-Chloropyridin-3- 20 mg cloprid yl)methyl]-4,5-dihydro-2- (nitroamino)-1H- imidazole-4,5-diol

155802-65-6 PS121 O H Fenamidone (S)-5-Methyl-5-phenyl-3- 20 mg N H3C N Metabolite phenylamino imidazolidine-2,4-dione N H O 332855-88-6 PS198 Chlozolinate Ethyl 3-(3,5-dichlorophe- 20 mg nyl)-5-methyl-2,4-dioxo- 5-oxazolidinecarboxylate

84332-86-5

PS017 O Dimethachlor-Metabo- 2-[(2-Hydroxy-acetyl)-(2- 20 mg O OH lite SYN 530561 methoxy-ethyl)-amino]-3- H3C N methyl benzoic acid HOOC CH3

1138220-18-4

PS028 O CH3 Metolachlor Metabolite (±)-2-[(2-Ethyl-6-methyl- 20 mg CGA 357704 phenyl) oxalyl amino] HOOC N COOH (racemate) propionic acid H3C CH3 -

PS029 Na+ S-Metolachlor Metabo- Sodium [(2-ethyl-6-me- 20 mg O O lite CGA 368208 thylphenyl) carbamoyl] -O S methane sulfonate NH O CH3 H3C 1173021-76-5

PS030 CH3 Metolachlor Metabolite (±)-2-[(2-Ethyl-6-methyl- 20 mg CGA 50267 phenyl) amino] propionic HN COOH (racemate) acid H3C CH3

82508-02-9 PS034 O S-Metolachlor Metabo- N-(2-Ethyl-6-methyl 20 mg lite CGA 50720 phenyl) oxamic acid HOOC NH

CH3 H3C 152019-74-4

WITEGA Laboratorien Berlin-Adlershof GmbH page 53 of 87 Pesticides PS035 O S-Metolachlor Metabo- N-(2-Ethyl-6-methylphe- 20 mg OH lite CGA 37735 nyl)-2-hydroxy acet- HN amide H3C CH3 948595-12-8

PS186 Metolachlor OA 2-[(2-Ethyl-6-methylphe- 20 mg nyl)(2-methoxy-1-methylethyl)amino]-2-oxoacetic

acid

152019-73-3

PS184 Metalaxyl-D6 N-(2,6-Dimethyl-D6- 20 mg phenyl)-N-(methoxyacetyl)-DL-alanine

methylester

PS045 O CH3 Metalaxyl Metabolite (±)-N-(2-Carboxy-6-me- 20 mg O CGA 108906 thylphenyl)-N-(meth- H C N COOH 3 oxyacetyl) alanine HOOC CH3

104390-56-9

PS046 O CH3 Metalaxyl Metabolite (±)-N-(2,6-Dimethyl-phe- 20 mg O CGA 62826 nyl)-N-(2-methoxyace- H C N COOH 3 tyl) alanine H3C CH3 87764-37-2

PS108 O O (S,S)-Metalaxyl Meta- (S)-2-[(2,6-Dimethyl- 20 mg O CH3 s bolite CGA 226048 phenyl)-2-methoxyacetyl H3C amino] propionic acid- CH s O CH3 3 (S)-1-methoxycarbonyl N CH3 O ethyl ester

O CH3 - PS109 O O (R,S)-Metalaxyl Meta- (R)-2-[(2,6-Dimethyl- 20 mg O CH 3 bolite CGA 226048 phenyl)-2-methoxyacetyl S H3C amino] propionic acid- CH R O CH3 3 (S)-1-methoxycarbonyl N CH3 O ethyl ester

O CH3 - PS134 O O Metalaxyl Metabolite 4-Methoxy-5-methyl-5H- 20 mg S CGA 363736 1,2-oxathiole-2,2-dioxide O

H3C O CH3 -

PS063 CD3 O Mecoprop-D6 2-(4-Chloro-2-methyl-D3- 20 mg D O phenoxy-D3) propanoic OH acid

CH3 Cl D - D

WITEGA Laboratorien Berlin-Adlershof GmbH page 54 of 87 Pesticides PS057 O Alachlor-D13 2-Chloro-2′,6′-diethyl-N- 20 mg H3C Cl (methoxymethyl)acetani- O N lide-D D D D D 13 D3C CD3 D D D 1015856-63-9 PS083 Cl Dichlorprop-butotyl 2-(2,4-Dichloro phenoxy) 20 mg propionic acid-2-butoxy- ethyl ester H3C O O Cl O O CH 3 53404-31-2 PS088 Cl Dichlorprop-iso-octyl 2-(2,4-Dichloro phenoxy) 20 mg propionic acid-(1-methyl CH3 heptyl) ester

H3C O Cl O O CH3 -

PS096 CD3 O Propachlor-D7 N-Isopropyl-D -N-phenyl- 20 mg D 7 Cl chloroacetamide D3C N

PS105 CH3 O Propachlor-2-hydroxy 2-Hydroxy-N-isopropyl- 20 mg OH N-phenyl-acetamide H3C N

42404-06-8 PS065 Cl O Prochloraz Metabolite 1-Propyl-1-[2-[2,4,6-tri- 20 mg O BTS 44595 chloro phenoxy]ethyl]- N NH 2 urea Cl Cl CH3 139520-94-8 PS066 Cl Prochloraz Metabolite N-Propyl-N-[2-(2,4,6-tri- 20 mg

O CH3 BTS 40348 chloro phenoxy)ethyl]- N amine H Cl Cl 67747-01-7 O PS006 H3C CH3 Aldicarb-sulfoxide 2-Methyl-2-(methylsulfi- 20 mg H3C N CH3 nyl)propanal-O-(methyl- N O S H amino carbonyl)oxime O 1646-87-3 PS175 Aldicarb-sulfone 2-Methyl-2-(methylsul- 20 mg (Aldoxycarb) fonyl)propanal-O-(me- thylamino carbonyl)oxime 1646-88-4

WITEGA Laboratorien Berlin-Adlershof GmbH page 55 of 87 Pesticides PS031 O Methiocarb-D3 3,5-Dimethyl-4-(methyl- 20 mg thio)phenyl-N-methyl-D3- CD3 O N carbamate H

H3C CH3 S 1581694-94-1 H3C PS032 O Methiocarb-sulfoxide Methyl carbamic acid-4- 20 mg CH3 methanesulfinyl-3,5-di- O N methyl phenylester H

H3C CH3 S 2635-10-1 O CH3 PS169 Methiocarb sulfone Methyl carbamic acid-4- 20 mg methanesulfonyl-3,5-dimethyl phenylester

2179-25-1

PS185 3,4,5-Trimethacarb (3,4,5-Trimethylphenyl) 20 mg N-methylcarbamate

2686-99-9 PS111 S Propylene thiourea 4-Methyl-imidazolidine-2- 20 mg thione HN NH

H3C 2122-19-2 PS114 Benalaxyl-M N-(2,6-Dimethylphenyl)- 20 mg N-(phenylacetyl)-D-ala- O O CH nine methyl ester 3 O

H3C N

CH3 CH3 98243-83-5

PS120 Thiacloprid-amid [3-(6-Chloro pyrid-3-yl 20 mg Cl methyl)thiazolidin-2- ylidene]urea N N N S 676228-91-4 O NH2 PS154 Clothianidin-D3 (E)-1-(2-Chloro-5- 20 mg thiazolylmethyl)-3- (methyl-D )-2- 3 nitroguanidine 1262776-24-8 WITEGA Laboratorien Berlin-Adlershof GmbH page 56 of 87 Pesticides PS155 Thiamethoxam-D3 3-(2-Chloro-5- 20 mg thiazolylmethyl)tetrahydro-5-methyl-D -N-nitro- 3 4H-1,3,5-oxadiazin-4- 1294048-82-0 imine

PS190 Dinotefuran-D3 (RS)-N-Methyl-D3-N′- 20 mg nitro-N″-[(tetrahydro-3- furanyl)methyl]guanidine

- PS189 Dinotefuran (RS)-N-Methyl-N′-nitro- 20 mg N″-[(tetrahydro-3- furanyl)methyl]guanidine

165252-70-0 PS192 Dinotefuran UF (R,S)-N-Methyl-N'- 20 mg [(tetrahydro-3- furanyl)methyl]urea

457614-34-5 PS197 Dinotefuran DN- (RS)-N-Methyl-N′-nitro- 20 mg picrate N″-[(tetrahydro-3- furanyl)methyl]guani- dinium picrate - PS130 O Fentrazamide 1-(2-Chlorophenyl)-1,4- 20 mg NH Metabolite dihydrotetrazol-5-one N N N 98377-35-6 Cl PS138 Cl Chlorbenside sulfoxide (4-Chlorobenzyl)-(4´- 20 mg chlorophenyl) sulfoxide S O Cl 7047-28-1 PS009 Cl Chlorbenside sulfone (4-Chlorobenzyl)-(4´- 20 mg chlorophenyl) sulfone S O O Cl 7082-99-7 PS116 O Cloquintocet [(5-Chloro-8-quinolinyl)- 20 mg oxy]acetic acid Cl O OH

N 88349-88-6

PS145 H3C CH3 H3C CH3 Amitraz-D3 N´-(2,4-Dimethylphenyl)- 10 mg N-[[(2,4-dimethylphenyl)- N N N imino]methyl]-N-methyl-

CD3 D3-methanimidamide -

PS144 H3C CH3 H3C CH3 Amitraz N´-(2,4-Dimethylphenyl)- 20 mg N-[[(2,4-dimethylphenyl)- N N N imino]methyl]-N-methyl-

CH3 methanimidamide 33089-61-1

WITEGA Laboratorien Berlin-Adlershof GmbH page 57 of 87 Pesticides

PS148 H3C Diethylamino ethyl 2-(Diethylamino) ethyl 100 mg O hexanoate hexanoate N O CH3 CH3 10369-83-2 PS164 Afoxolaner 4-[5-[3-Chloro-5- 20 mg (trifluoromethyl)phenyl]- 5-trifluoromethyl-4,5-

dihydroisoxazol-3-yl]-N-

[2-oxo-2-[(2,2,2- trifluoroethyl)amino]e- 1093861-60-9 thyl]-1-naphthalencarb- oxamide PS166 Lotilaner (S)-5-[5-(3,4,5- 20 mg Trichlorophenyl)-5- trifluoromethyl-4,5-

dihydroisoxazol-3-yl]-3- methylthiophene-2- carboxylic acid [(2,2,2- 1369852-71-0 trifluoroethyl carbamoyl) methyl] amide PS167 Sarolaner (S)-1-[5´-(5-(3,5- 20 mg Dichloro-4-fluorophenyl)- 5-trifluoromethyl-4,5-

dihydroisoxazol-3-yl)- 3´H-spiro[acetidine-3,1´- 1398609-39-6 isobenzofuran]-1-yl]-2- (methylsulfonyl)ethanone PS178 Chloridazon-desphe- 5-Amino-4-chloro-2H- 20 mg nyl pyridazin-3-one

6339-19-1 PS003 2,4-DXPD N,N’-Bis(2,4-dimethyl- 20 mg phenyl)-p-phenylen- diamine

76154-76-2 PS191 Phorate-oxon O,O’-Diethyl-S- 20 mg (ethylthiomethyl) phosphorothioate 2600-69-3

PS193 Phorate-oxon- O,O’-Diethyl-S- 20 mg sulfoxide (ethylsulfinylmethyl) phosporothioate 2588-05-8 PS194 Phorate-oxon-sulfon O,O’-Diethyl-S- 20 mg (ethylsulfonylmethyl) phosphorothioate 2588-06-9

WITEGA Laboratorien Berlin-Adlershof GmbH page 58 of 87 Steroids Order Formula Name Chemical Name Offer No. CAS Number HO ST001 H C Methyltestosterone-D3 17β-hydroxy-17-methyl- 10 mg 3 CD3 D3-4-androsten-3-one H C H 3 H H O 96425-03-5 ST013 Methyltestosterone 17β-Hydroxy-17-methyl- 10 mg androst-4-en-3-one 100 mg

58-18-4

ST012 Methandienone-D3 17β-Hydroxy-17-methyl- 10 mg D3-androsta-1,4-dien-3- one

869287-60-5

ST017 Medroxyprogesterone 17α-Hydroxy-6α-methyl- 10 mg 4-pregnene-3,20-dione 100 mg

520-85-4

ST002 Medroxyprogesterone- 17α-Hydroxy-6α-methyl- 5 mg D3 D3-4-pregnene-3,20- dione

162462-69-3

O ST003 H3C 17α-Acetoxyprogeste- 17α-Acetoxy-D3-4- 10 mg

CH3 rone-D3 pregnene-3,20-dione O CD3

CH H 3 O

H H O - ST020 Testosterone 17β-Hydroxy androst-4- 10 mg en-3-one 100 mg

58-22-0

ST004 HO Testosterone- 17β-Hydroxy-4- 10 mg H3C D 16,16,17-D3 androsten-3-one- D H3C H 16,16,17-D3 D H H O 77546-39-5

WITEGA Laboratorien Berlin-Adlershof GmbH page 59 of 87 Steroids ST021 Testosterone- 17β-(1-Oxopropoxy) 10 mg 16,16,17-D3 propiona- androst-4-en-3-one- te 16,16,17-D3

876054-54-5

ST005 O Testosterone- 17β -(1-Oxo-3-phenyl- 10 mg 16,16,17-D3-3-phenyl prop-oxy) androst-4-en- O H C 3 D propionate 3-one-16,16,17-D3 D H3C H D 876054-55-6 H H O ST018 Nortestosterone 17β-Hydroxy-4-estren-3- 10 mg (Nandrolone) one 100 mg

434-22-0 ST006 HO Nortestosterone-D3 17β-Hydroxy-4-estren-3- 10 mg H3C D (Nandrolone-D3) one-16,16,17-D D 3 H D H H O 120813-22-1 ST019 Trenbolone 17β-Hydroxyestra- 10 mg 4,9,11-trien-3-one 100 mg

10161-33-8

ST007 HO Trenbolone-D3 17β-Hydroxyestra- 10 mg H3C D 4,9,11-trien-3-one- D H 16,16,17-D3 D H O 2026642-62-4 ST008 H 17α-Nortestosterone 17α-Hydroxy-4-estren-3- 10 mg H3C OH (17α-Nandrolone) one H

H H 20708-81-0 O ST009 OH 17β-Estradiol-D3 Estra-1,3,5(10)-trien- 10 mg CH3 D D 3,17β-diol-16,16,17-D3 20 mg H D

H H 79037-37-9 HO ST010 17β-Boldenone-D3 17β-Hydroxy-androsta- 10 mg 1,4-dien-3-one-16,16,17- D 3 1224710-35-3

WITEGA Laboratorien Berlin-Adlershof GmbH page 60 of 87 Steroids ST016 17β-Boldenone 17β-Hydroxy-androsta- 10 mg 1,4-dien-3-one 100 mg

846-48-0

ST015 17-O-Methylboldeno- 17β-Methoxy-D3-andros- 10 mg ne-D3 ta-1,4-dien-3-one 20 mg

ST014 17-O-Methylboldeno- 17β-Methoxy-androsta- 20 mg ne 1,4-dien-3-one

20401-12-1

ST011 Hydrocortisone 21- 21-(3-Carboxy-1-oxo- 100 mg hemisuccinate propoxy)-11ß,17-dihydroxy-pregn-4-ene- 3,20-dione

2203-97-6

ST022 Testosterone-16,16, 17β-(1-Oxo-4-methyl- 10 mg 17-D3-isocaproate pentyloxy) androst-4-en- 3-one-16,16,17-D3

ST023 Testosterone-16,16, 17β-(1-Oxodecyloxy) 10 mg 17-D3-decanoate androst-4-en-3-one- 16,16,17-D3

876054-57-8

WITEGA Laboratorien Berlin-Adlershof GmbH page 61 of 87

Sulfonamides Order Formula Name Chemical Name Offer No. CAS Number

SA001 NH2 Sulfadimethoxine-D6 4-Amino-N-(2,6-dimeth- 50 mg oxy-D6-pyrimidin-4-yl)- 100 mg benzenesulfonamide

S O HN O

D3C CD3 73068-02-7 O N O Me SA015 O Sulfadimethoxine- 4-Amino-N-[2,6-dimeth- 25 mg 13C6 oxy-pyrimidin-4-yl]- 50 mg H 13 O O N N benzene- C6- H 13 C S Me sulfonamide 13C 13C N O H 13C 13C 13 H2N C H 1334378-48-1 H

SA002 NH2 Sulfadoxine-D3 4-Amino-N-(5-methoxy- 50 mg 6-methoxy-D3-pyrimidin- 100 mg 4-yl)-benzenesulfon-

amide O S HN O O H C N 3 1262770-70-6 D3C O N NH SA003 2 Sulfamethoxypyrida- 4-Amino-N-(6-methoxy- 25 mg zine-D3 D3-pyridazin-3-yl)-ben- 50 mg zenesulfonamide

O S HN O N N

D O D 1172846-03-5 D O SA004 H O O N Sulfamethoxazole- 4-Amino-N-(5-methyl- 25 mg CH H 13C S 3 13C6 isoxazol-3-yl)-benzene- 50 mg 13C 13C N 13 H C6-sulfonamide 13 13 C C 13 H2N C H H 1196157-90-0 SA005 H N Sulfathiazole-13C6 4-Amino-N-thiazol-2-yl- 25 mg O O 13 13 benzene- C -sulfon- H C S 6 50 mg 13C 13C N S amide H 13C 13C 13 H2N C H 1196157-72-8 H

WITEGA Laboratorien Berlin-Adlershof GmbH page 62 of 87 Sulfonamides 13 SA006 H O O Sulfanilamide-13C6 4-Amino-benzene- C6- 25 mg H 13C S sulfonamide 50 mg 13C 13C NH 2 13C 13C 13 H2N C H H 1196157-89-7 SA026 H O O O Sulfacetamide-13C6 N-Acetyl-4-amino- 25 mg 13 H 13C S benzene- C6-sulfon- 50 mg 13C 13C N CH3 amide H 13C 13C 13 H2N C H H - SA017 O O O Sulfacetamide N-(4-Aminobenzenesul- 50 mg S fonyl)acetamide N CH3 H H2N 144-80-9 SA018 O O H 4-Acetylsulfanilamide- 4-Acetylaminobenzene- 25 mg S 13C H 13C6 13C6-sulfonamide H N 50 mg 2 13C 13C O

13 13 C C H 13C N CH3 H 1655498-04-6 H SA030 Diacetylsulfanilamide- N-Acetyl-4-acetamido 25 mg 13 13C6 benzene- C6-sulfon- 50 mg amide

- SA007 Sulfamerazine-13C6 4-Amino-N-(4-methyl- 25 mg H O O N 13 pyrimidin-2-yl)-benzene- H C 13 50 mg 13 13 S C C N N CH3 C6-sulfonamide H 13C 13C 13 H2N C H H 1196157-80-8 SA008 Sulfadiazine-13C6 4-Amino-N-pyrimidin-2- 25 mg H O O N 13 yl-benzene- C6-sulfon- 13 50 mg H C S amide 13C 13C N N H 13C 13C 13 H2N C H 1189426-16-1 H CH SA009 3 Sulfadimidine-13C6 4-Amino-N-(4,6- 25 mg dimethyl-pyrimidin-2-yl)- H N Sulfamethazine-13C6 50 mg O O benzene-13C -sulfon- H 13C 6 13 13 S C C N N CH3 amide H 13C 13C H N 13 2 C H 77643-91-5 H SA027 CH3 Acetylsulfadimidine 4-Acetylamino-N-(4,6- 50 mg

N dimethyl-pyrimidin-2-yl)- O O benzene-sulfonamide S O N N CH3 H H3C N H 100-90-3

WITEGA Laboratorien Berlin-Adlershof GmbH page 63 of 87 Sulfonamides SA010 N Cl Sulfachloropyridazine- 4-Amino-N-(6-chloro- 25 mg H O O N 13C 13C6 pyridazin-3-yl)-benzene- 50 mg H13 13 S 13 C C N C6-sulfonamide H 13C 13C 13 H2N C H H -

SA011 H N Sulfapyridine-13C6 4-Amino-N-pyridin-2-yl- 25 mg O O 13 13 H C S benzene- C6-sulfon- 50 mg 13C 13C N amide H 13C 13C 13 H2N C H 1228182-45-3 H SA012 N Sulfaquinoxaline-13C6 4-Amino-N-quinoxalin-2- 25 mg H O O 13 13 yl-benzene- C6- H C S 50 mg 13C 13C N N sulfonamide H 13C 13C 13 H2N C H 1202864-52-5 H

SA013 CH3 Sulfamethizole-13C6 4-Amino-N-(5-methyl- 25 mg [1,3,4]thiadiazol-2-yl)- H O O S 50 mg N benzenesulfonamide- H 13C 13 13 13 S C C C N N 6 H 13C 13C 13 H2N C H 1334378-92-5 H SA014 H N Sulfisoxazole-13C6 4-Amino-N-(3,4- 25 mg O O O 13 H C CH3 dimethyl-isoxazol-5-yl) S (Sulfafurazole-13C6) 13 50 mg 13C 13C N benzene- C - 6 13 13 H C C CH3 sulfonamide H2N 13C H H 1334378-46-9 SA016 O2N Sulfanitran-13C6 N-[4-[[(4-Nitrophenyl)a- 25 mg O H O mino]sulfonyl]phenyl- S 13C H 50 mg N 13 13C 13C C6]acetamide H O 13C 13C H 13C N CH3 1353867-79-4 H H SA029 Sulfanitran N-[4-[[(4-Nitrophenyl) 100 mg amino] sulfonyl]phenyl] acetamide

122-16-7 SA019 N Sulfachloropyrazine- 4-Amino-N-(6-chloro- 25 mg H O O 13C6 pyrazin-2-yl)-benzene- 13 13 50 mg H 13 C 13 S C6-sulfonamide C C NH N Cl 13 13 C 13 C H2N C H 1416711-61-9 H

SA020 H Sulfaphenazole-13C6 4-Amino-N-(2-phenyl- 25 mg O O 13 N 2H-pyrazol-3-yl)-benze- H C S 13 50 mg 13 13 N ne- C -sulfonamide C C NH 6 13 13 C 13 C H N C H 2 1420043-53-3 H

WITEGA Laboratorien Berlin-Adlershof GmbH page 64 of 87 Sulfonamides

SA021 CH3 Sulfapyrazole-13C6 4-Amino-N-(5-methyl-2- 25 mg H O O phenyl-2H-pyrazol-3-yl)- 50 mg 13 13 H C S N benzene- C -sulfon- 13 13 6 C C N N amide H 13C 13C 13 H2N C H 1420043-51-1 H

SA022 H Sulfamonomethoxine- 4-Amino-N-(6-methoxy- 25 mg O O N N H 13 13C6 hydrate (see pyrimidin-4-yl)-benzene- C S CH 50 mg 13C 13C 3 13 N O Data Sheet) C6-sulfonamide hydrate H 13C 13C 13 (see Data Sheet) H2N C H x mole H O H 2 1416768-32-5 (anhydrous) SA028 Sulfamonomethoxine 4-Amino-N-(6-methoxy 50 mg O O N N pyrimidin-4-yl) benzene S CH3 N O sulfonamide H

H2N 1220-83-3

SA023 H O O H Dapsone-13C12 4,4’-Diaminodiphenyl- 25 mg H 13C 13C H 13 13 13 S 13 13 C -sulfone C C C C 12 50 mg 13C 13C 13C 13C 13 13 1632119-29-9 H2N C H H C NH2 H H

SA024 O CH3 Sulfaethoxypyridazine- 4-Amino-N-(6-ethoxy-py- 10 mg H O O 13C6 ridazin-3-yl)-benzene- H 13C S N 13 20 mg 13C 13C N N C6-sulfonamide H 13C 13C 13 H2N C H - H

WITEGA Laboratorien Berlin-Adlershof GmbH page 65 of 87

Tranquilizer Order Formula Name Chemical Name Offer No. CAS Number

S TR012 Acepromazine-D6 1-[10-(3-Dimethyl-D6- 50 mg COOH maleate amino-propyl)-10H- CH3 100 mg N phenothiazin-2-yl]- O ethanone maleate COOH

CD3 N 1331655-50-5 CD3 TR011 S Acepromazine 1-[10-(3-Dimethylamino- 50 mg hydrochloride propyl)-10H-phenothia- 100 mg CH3 N zin-2-yl]-ethanone H C O hydrochloride 3 N HCl CH 3 973-12-6 TR022 S Acepromazine 1-[10-(3-Dimethylamino- 50 mg COOH maleate propyl)-10H-phenothia- CH3 100 mg N zin-2-yl]-ethanone O maleate COOH

CH3 N 3598-37-6 CH3 D D TR002 Azaperol-D4 1-(4-Fluoro-phenyl-D4)-4- 25 mg OH N F N N (4-pyridin-2-yl-piperazin- 50 mg 1-yl)-butan-1-ol - D D TR008 OH N Azaperol 1-(4-Fluoro-phenyl)-4-(4- 50 mg F N N pyridin-2-yl-piperazin-1- 100 mg yl)-butan-1-ol 2804-05-9

D D TR003 Azaperone-D4 1-(4-Fluoro-phenyl-D4)-4- 25 mg O N F N N (4-pyridin-2-yl-piperazin- 50 mg 1-yl)-butan-1-one 1173021-72-1 D D TR009 O N Azaperone 1-(4-Fluoro-phenyl)-4-(4- 50 mg F N N pyridin-2-yl-piperazin-1- 100 mg yl)-butan-1-one 1649-18-9

H TR004 N Carazolol-D7 1-(9H-Carbazol-4-yloxy)- 25 mg 3-isopropyl-D7-amino- 50 mg propan-2-ol

O D D HO D N H D D 1173021-02-7 D D

WITEGA Laboratorien Berlin-Adlershof GmbH page 66 of 87 Tranquilizer

H TR005 N Carazolol 1-(9H-Carbazol-4-yloxy)- 50 mg 3-isopropyl-amino- 100 mg propan-2-ol

HO CH N 3 H CH 57775-29-8 3 TR006 S Chlorpromazine-D6 [3-(2-chloro- 50 mg hydrochloride phenothiazin-10-yl)- 100 mg N Cl propyl]-dimethyl-D6- CD H Cl 3 amine hydrochloride N 1228182-46-4 CD 3 TR029 7-Hydroxy chlorprom- 2-Chloro-10-[3-(dimethyl- 25 mg azine-D6 D6-amino)propyl]-7- hydroxy phenothiazine

TR026 S OH 7-Hydroxy chlorprom- 2-Chloro-10-[3-(dimethyl- 50 mg azine amino)propyl]-7-hydroxy 100 mg Cl N phenothiazine

CH3 N CH3 2095-62-7

S TR007 Propionylpromazine- 1-[10-(3-Dimethyl-D6- 50 mg D6 hydrochloride amino-propyl)-10H- 100 mg D N CH D 3 phenothiazin-2-yl]- O propan-1-one D N HCl hydrochloride D D D 1262770-67-1 TR010 D Xylazine-D6 (5,6-Dihydro-4H- 25 mg D D [1,3]thiazin-2-yl)-(2,6- 50 mg H S dimethyl-D -phenyl)- N 6 amine N D 1228182-53-3 D D TR013 S Triflupromazine-D6- 2-Trifluoromethyl-10-[3- 50 mg hydrochloride (dimethyl-D6-amino)- 100 mg N CF3 propyl]-10H-phenothiazine hydrochloride HCl

CD3 N 1416711-36-8 CD3 TR014 S Prothipendyl-D6- (3-Benzo[b]pyrido[2,3- 50 mg O OH oxalate e][1,4]thiazin-10-yl- 100 mg N N propyl)-dimethyl-D6- O OH amine oxalate

CD3 N - CD3 WITEGA Laboratorien Berlin-Adlershof GmbH page 67 of 87 Tranquilizer

O CD3 TR015 O Reserpine-D9 (3β,16β,17α,18β,20α)- 10 mg N H O 11,17-Dimethoxy-18- 25 mg H3C O CD3 O N H [[3,4,5-tri(methoxy-D3)- H H O O O CH3 D3C benzoyl]oxy]yohimban- O 16-carboxylic acid H3C 84759-11-5 methylester

S TR016 O Alimemazine-D6 Dimethyl-D6-(2-methyl-3- 50 mg maleate phenothiazin-10-yl-pro- 100 mg N OH pyl)-amine maleate OH Trimeprazine-D6 CH3 maleate O CD3 N - CD3 S TR017 Promazine-D6 Dimethyl-D6-(3-phenothi- 50 mg hydrochloride azin-10-yl-propyl)-amine 100 mg N HCl hydrochloride

CD3 N 1246819-33-9 CD3 TR018 S Promethazine-D6 10-[2-(Dimethylamino- 50 mg hydrochloride D6)propyl]phenothiazine 100 mg N HCl hydrochloride CH3 1189947-02-1 N D3C CD3 TR019 S Chlorprothixene-D6 (Z)-2-Chloro-N,N-dime- 25 mg 9,8 thyl-D6-thioxanthen-Δ 50 mg Cl propylamine

CD3 N 1246912-83-3 CD3 TR020 S (±)-Levomepromazine- [3-(2-Methoxy-pheno- 50 mg D6 maleate thiazin-10-yl)-2-methyl- CH3 100 mg N O COOH (±)-Methotrimeprazine- propyl]-dimethylamine-D6 CH 3 D6 maleate maleate COOH CD3 N CD3 - TR024 S (±)-O-Desmethyl-levo- [3-(2-Hydroxypheno- 25 mg mepromazine-D6 thiazin-10-yl)-2-methyl- 50 mg N OH propyl]dimethylamine-D6 CH3

CD3 N - CD3 CD TR023 3 Methapyrilene-D6 N,N-Dimethyl-D6-N`-(2- 25 mg N CD3 fumarate pyridyl)-N`-(2-thienyl- 50 mg HOOC methyl)-1,2-ethan- N N diamine fumarate COOH

S 1613439-61-4 TR027 Detomidine 5-(2,3-Dimethylbenzyl)- 20 mg H CH3 hydrochloride 1H-imidazol N HCl hydrochloride CH3 N 90038-01-0

WITEGA Laboratorien Berlin-Adlershof GmbH page 68 of 87 Tranquilizer TR028 H H Haloperidol-13C6 4-[4-(4-Chlorophenyl)-4- 10 mg 13C 13C O 13 13 hydroxy-1-piperidinyl]-1- F C C 13 25 mg 13 13 (4-fluorophenyl- C ) C C OH 6 H H N Cl butan-1-one -

WITEGA Laboratorien Berlin-Adlershof GmbH page 69 of 87

Plasticizers (Phthalate) Order Formula Name Chemical Name Offer No. CAS Number PS137 D O Mono-2-ethylhexyl Mono-2-ethylhexyl 20 mg D phthalate-D4 phthalate-D4 O CH 3 OH D CH3 D O 1276197-22-8

PS008 CH3 Di-(2-ethylhexyl) Bis(2-ethylhexyl) phtha- 20 mg phthalate-D4 late-D4 D O CH3

D O O D

D O CH3 93951-87-2 CH3

PS013 Dibenzyl phthalate-D4 Dibenzyl phthalate-D4 20 mg

D O

O D

D O

1015854-62-2

PS014 D O Dicyclohexyl phthala- Dicyclohexyl phthalate- 20 mg te-D4 D4 D O

O D

D O 358731-25-6

PS015 D O Diethyl phthalate-D4 Diethyl phthalate-D4 20 mg D O CH3

O CH3 D D O 93952-12-6

PS016 H3C CH3 Di-iso-butyl phthalate- Diisobutyl phthalate-D 20 mg D O 4 D4 D O O D

D O H3C CH3 358730-88-8

PS020 D O Di-n-butyl phthalate- Di-n-butyl phthalate-D4 20 mg D D4 O CH 3 O CH3 D D O 93952-11-5

WITEGA Laboratorien Berlin-Adlershof GmbH page 70 of 87 Plasticizers (Phthalate)

PS021 D O Di-n-hexyl phthalate- Di-n-hexyl phthalate-D4 20 mg D D4 O CH 3 O CH3 D D O 1015854-55-3

D O PS022 Di-n-octyl phthalate- Di-n-octyl phthalate-D4 20 mg D D4 O CH3

O CH3 D D O 93952-13-7

PS023 D O Di-n-pentyl phthalate- Di-n-pentyl phthalate-D4 20 mg D CH3 D4 O

O D CH3 D O 358730-89-9

PS141 D O Benzylbutyl phthalate- Benzyl butyl phthalate-D4 20 mg D D4 O CH 3 O D D O 93951-88-3

PS146 D O CH3 CH3 Bis(3,5,5-trimethyl- Bis(3,5,5-trimethylhexyl) 20 mg CH3 D hexyl) phthalate-D4 phthalate-D4 O CH 3 Diisononyl phthalate O CH3 D CH3 D O CH3 CH3 -

PS147 O CH3 CH3 Bis(3,5,5-trimethyl- Bis-(3,5,5-trimethylhexyl) 20 mg CH 3 hexyl) phthalate phthalate O CH 3 Diisononyl phthalate O CH3

CH3 O CH3 CH3 - PS159 O Bis(2-ethoxyethyl) Bis(2-ethoxyethyl) phtha- 20 mg

O CH3 phthalate late O

O O CH3 O 605-54-9

PS160 H3C CH3 Bis(4-methylpentyl) Bis(4-methylpentyl) 20 mg O phthalate phthalate O O

O H3C CH3 259139-51-0

PS161 O CH3 CH3 Bis(4-methylpent-2- Bis(4-methylpent-2- 20 mg yl)phthalate yl)phthalate O CH 3 O CH 3 84-63-9 O CH3 CH3 WITEGA Laboratorien Berlin-Adlershof GmbH page 71 of 87

Other Products Order Formula Name Chemical Name Offer No. CAS Number 1,3-Bis(4-nitrophenyl)- OP001 D D BNPH-D8 50 mg DNC-D8 urea-D8 O2N D D 100 mg NO2 O 4,4´-Dinitrocarbanilide-D8

D N N D H H 1156508-87-0 D D H H 1,3-Bis(4-nitrophenyl- OP057 BNPH-13C12 13 25 mg 13 13 C6)-urea O2N C H H C NO2 13C 13C O 13C 13C DNC-13C12 13C 13C 13C 13C H 13C N N 13C H H H - H H

OP092 D D D D Imidocarb-D8-2HCl 1,3-Bis[3-(4,5-dihydro- 25 mg 1H-imidazol-D -2-yl)- D D D D hydrate (see Data 8 50 mg H2N N N NH2 Sheet) phenyl]-urea dihydrochloride hydrate Cl Cl O (see Data Sheet)

N N H H - x mole H2O OP093 Imidocarb-2HCl 1,3-Bis[3-(4,5-dihydro- 50 mg H2N N N NH2 1H-imidazol-2-yl)- hydrate (see Data 100 mg phenyl]-urea Cl Cl Sheet) O dihydrochloride hydrate

(see Data Sheet) N N H H 5318-76-3 x mole H2O (anhydrous) OP002 OH OH threo-m-Chloramphe- 2,2-Dichloro-N- 25 mg 1 nicol [(1RS,2RS)-2-hydroxy-1- 50 mg 2 Cl hydroxymethyl-2-(3-nitro-

HN phenyl) ethyl] acetamide Cl (mixture of enantiomers) NO2 O (1RS, 2RS) 138125-72-1 OP003 OH OH erythro-m-Chloram- 2,2-Dichloro-N- 25 mg 1 phenicol [(1RS,2SR)-2-hydroxy-1- 50 mg 2 Cl hydroxymethyl-2-(3-nitro-

HN phenyl) ethyl] acetamide Cl (mixture of enantiomers) NO2 O (1RS, 2SR) 138125-71-0 OP027 D HO D OH threo-Chloramphe- 2,2-Dichloro-N- 10 mg [(1RS,2RS)-2-deutero-2- D 1 nicol-D5 20 mg hydroxy-1-hydroxy- 2 Cl methyl-2-(4-nitrophenyl- HN O2N D Cl D4) ethyl] acetamide D O (mixture of enantiomers) - (1RS, 2RS)

WITEGA Laboratorien Berlin-Adlershof GmbH page 72 of 87 Other Products

OP028 D HO D OH erythro-Chloramphe- 2,2-Dichloro-N- 10 mg [(1RS,2SR)-2-deutero-2- D 1 nicol-D5 20 mg hydroxy-1-hydroxy- 2 Cl methyl-2-(4-nitrophenyl- HN O2N D Cl D4) ethyl] acetamide D O (mixture of enantiomers) - (1RS, 2SR) OP073 Dextramycin 2,2-Dichloro-N-[(1S,2S)- 50 mg 2-hydroxy-1-hydroxy- 100 mg methyl-2-(4-nitrophenyl) ethyl] acetamid 134-90-7

OP164 Florfenicol 2,2-Dichloro-N-[(1S,2R)- 10 mg 2-hydroxy-1-fluorome-

thyl-2-(4-methylsulfonylphenyl) ethyl] acetamide

73231-34-2

2,2-Dichloro-N- OP165 Florfenicol-D4 (mixture 5 mg [(1RS,2SR)-1,2-dideu- of enantiomers) 10 mg tero-2-hydroxy-1-fluoro-

methyl-D2-2-(4-methylsulfonylphenyl) ethyl] acetamide (mixture of - enantiomers)

OP079 Florfenicol amine (1R,2S)-2-Amino-3- 50 mg fluoro-1-(4-methane- 100 mg sulfonylphenyl) propan- 1-ol 76639-93-5

(1RS,2SR)-2-Amino-3- OP163 Florfenicol amine-D4 5 mg fluoro-1-(4-methane- trifluoroacetate 10 mg (mixture of enantio- sulfonylphenyl)-1,2,3,3- mers) tetradeutero-propan-1-ol trifluoroacetate (mixture

of enantiomers) - OP159 threo-Thiamphenicol- 2,2-Dichloro-N- 5 mg D4 [(1RS,2RS)-1,2- 10 mg dideutero-2-hydroxy-1- (Thiamphenicol-D4) hydroxymethyl-D2-2-(4- methylsulfonylphenyl) ethyl] acetamide (mixture - of enantiomers)

OP160 erythro-Thiampheni- 2,2-Dichloro-N- 5 mg [(1RS,2SR)-1,2- col-D4 10 mg dideutero-2-hydroxy-1- (epi-Thiamphenicol- hydroxymethyl-D -2-(4- D4) 2 methylsulfonylphenyl) ethyl] acetamide (mixture of enantiomers) - WITEGA Laboratorien Berlin-Adlershof GmbH page 73 of 87 Other Products OP161 Thiamphenicol 2,2-Dichloro-N-[(1R,2R)- 10 mg 2-hydroxy-1-

hydroxymethyl-2-(4- methylsulfonylphenyl) ethyl] acetamide

15318-45-3

OP011 HO Sudan-I-D5 1-Phenyl-D5-azo- 50 mg D D naphthalen-2-ol 100 mg N

D N

D D 752211-63-5

OP077 CH3 Sudan-II-D6 1-(2,4-Dimethyl-phenyl- 25 mg azo)-naphthalene-D6-2-ol 50 mg

CH3 N D N D OH

D D 1014689-15-6 D D OP012 D Sudan-IV-D6 1-(2-Methyl-4-o-tolylazo- 25 mg HO D phenylazo)-naphthalen- 50 mg N D D6-2-ol N N N D D D 1014689-18-9

H N 13 OP146 2 Chrysoidine-13C6 4-Phenyl- C6-azo-1,3- 10 mg H H (Chrysoidine G/Y- phenylenediamine 13 25 mg C 13 C N NH2 H 13 13C6; Solvent Orange C 13C N 3-13C6) 13C 13C - H H

Me N NMe OP022 2 2 Malachite green-D5 Bis-(4-dimethylamino- 25 mg picrate phenyl)-phenyl-D5- + O 50 mg C O N NO carbenium picrate D D 2 2

D D 1258668-21-1 NO D 2 OP152 Malachite green-D5 Bis (4-dimethylamino- 25 mg tetrafluoroborate phenyl) phenyl-D5- 50 mg carbenium tetrafluoroborate

WITEGA Laboratorien Berlin-Adlershof GmbH page 74 of 87 Other Products

Me N NMe OP015 2 2 Leucomalachite Bis-(4-dimethylamino- 50 mg D green-D6 (LMG-D6) phenyl)-phenyl-D5- 100 mg methane-D1 D D

D D 1173021-13-0 D

Me N NMe OP017 2 2 Leucomalachite Bis-(4-dimethylamino- 50 mg H green-D5 (LMG-D5) phenyl)-phenyl-D5- 100 mg methane D D

D D 947601-82-3 D

H C CH OP045 3 N 3 Crystal violet-D6 4,4’-Bis-(dimethylamino- 25 mg hydrate (see Data phenyl)-4”-dimethyl- 50 mg Sheet) amino-D6-phenyltritylium - chloride hydrate (see Cl x mole H2O Data Sheet) +

H C CD 3 N N 3 CH CD 3 3 1266676-01-0

OP046 CH3 Leuco crystal violet-D6 Bis-(4-dimethylamino- 25 mg H C N 3 phenyl)-4-dimethyl- 50 mg amino-D -phenyl- 6 methane CD3 N CD 3

H3C N 1173023-92-1 CH 3 OP112 H3C CH3 Brilliant green-D5 Bis-(4-diethylamino- 10 mg hydrogen sulfate phenyl)-phenyl-D - H3C N N CH3 5 25 mg hydrate (see Data carbenium hydrogen C Sheet) sulfate hydrate (see Data HSO - D D 4 Sheet) x mole H2O D D D -

OP113 H3C CH3 Brilliant green Bis-(4-diethylamino- 25 mg hydrogen sulfate phenyl)-phenyl- H3C N N CH3 hydrate (see Data carbenium hydrogen C Sheet) sulfate hydrate (see Data HSO - 4 Sheet) x mole H O 2 -

NH OP147 Auramine-D12 4,4´-Dimethyl-D6-amino 10 mg benzophenone imine 25 mg

D3C CD3 N N 1815617-39-0 CD3 CD3

WITEGA Laboratorien Berlin-Adlershof GmbH page 75 of 87 Other Products

CH OP019 3 Toltrazuril-D3 1-Methyl-D3-3-[3-methyl- 25 mg O F O D 4-(4-trifluoromethyl- 50 mg F D sulfanyl-phenoxy)- F S N N D phenyl]-[1,3,5]triazinane- O N O 1353867-75-0 2,4,6-trione H

CH OP030 3 Toltrazuril 1-Methyl-3-[3-methyl-4- 50 mg O F O (4-trifluoromethyl- F 100 mg CH3 sulfanyl-phenoxy)- F S N N phenyl]-[1,3,5]triazinane- O N O 69004-03-1 2,4,6-trione H CH OP031 3 Toltrazuril sulfoxide 1-Methyl-3-[3-methyl-4- 50 mg O F O (4-trifluoromethane- F 100 mg CH3 sulfinyl-phenoxy)- F S N N phenyl]-[1,3,5]triazinane- O O N O 69004-15-5 2,4,6-trione H CH OP095 3 Toltrazuril sulfone-D3 1-Methyl-D3-3-[3-methyl- 10 mg O F O D Ponazuril-D3 4-(4-trifluoromethane- 25 mg F D sulfonyl-phenoxy)- F S N N D O O phenyl]-[1,3,5]triazinane- O N O 1346602-48-9 2,4,6-trione H CH OP032 3 Toltrazuril sulfone 1-Methyl-3-[3-methyl-4- 50 mg O F O (4-trifluoromethane- F Ponazuril 100 mg CH3 sulfonyl-phenoxy)- F S N N O O phenyl]-[1,3,5]triazinane- O N O 69004-04-2 2,4,6-trione H OP115 H Diclazuril-methyl 2-(4-Chlorophenyl)-2- 10 mg O N O [2,6-dichloro-4-(3,5- 20 mg dioxo-4,5-dihydro-3H- Cl N N 1,2,4-triazin-2-yl)phe- H3C NC nyl]propionitrile Cl

103337-71-9 Cl OP020 D O QCA-D4 Quinoxaline-2-carboxylic 25 mg D N acid-D4 50 mg OH

D N - D

OP123 CD3 QCA-methylester-D3 Quinoxaline-2-carboxylic 25 mg O acid methylester-D3 N 50 mg O N - OP033 O QCA-Methyl ester Quinoxaline-2-carboxylic 50 mg N CH acid methyl ester 100 mg O 3

N 1865-11-8 OP173 MQCA 3-Methylquinoxaline-2- 10 mg carboxylic acid 25 mg 74003-63-7

WITEGA Laboratorien Berlin-Adlershof GmbH page 76 of 87 Other Products OP174 MQCA-13C6 3-Methylquinoxaline- 10 mg 13 C6-2-carboxylic acid 20 mg

OP081 Olaquindox-D4 3-Methyl-quinoxaline-2- 10 mg O O D D + carboxylic acid (2-hydro- 25 mg N OH xyethyl-D )-amide 1,4- N 4 H dioxide D D + N CH 3 1189487-82-8 O

OP158 O O Olaquindox 3-Methyl-quinoxaline-2- 100 mg carboxylic acid (2-hydro- N OH xyethyl)-amide 1,4- N H dioxide

N CH3 23696-28-8 O OP155 Mequindox-13C6 2-Acetyl-3-methylquinox- 10 mg 13 aline- C6-1,4-dioxide 20 mg

- OP114 O- O Mequindox 2-Acetyl-3-methylquinox- 10 mg + N aline-1,4-dioxide 25 mg CH3

+ N CH3 - O 13297-17-1 OP156 Desoxy-Mequindox- 2-Acetyl-3-methylquinox- 10 mg 13 13C6 aline- C6 25 mg

- OP151 O Desoxy-Mequindox 2-Acetyl-3-methylquinox- 25 mg N aline 50 mg CH3

N CH3 22059-64-9 OP177 Quinoceton-13C6 1-(3-Methyl-1,4-dioxido- 10 mg 2-quinoxalinyl)-3-phenyl- 20 mg 13C -prop-2-en-1-one 6 -

OP168 Quinoceton 1-(3-Methyl-1,4-dioxido- 10 mg 2-quinoxalinyl)-3-phenyl- 25 mg 2-propen-1-one

81810-66-4

WITEGA Laboratorien Berlin-Adlershof GmbH page 77 of 87 Other Products OP178 Bisdesoxyquinoceton- 1-(3-Methyl-2-quinox- 10 mg 13 13C6 alinyl)-3-phenyl- C6- 20 mg prop-2-en-1-one

- OP176 Bisdesoxyquinoceton 1-(3-Methyl-2-quinox- 10 mg alinyl)-3-phenyl-2- 25 mg propen-1-one

80109-63-3

O- OP149 H Carbadox-D3 (Quinoxalin-2-yl methyle- 10 mg N+ N O ne)hydrazinecarboxylic 20 mg N CD3 acid methyl-D ester 1,4- 3 O dioxide N+ 1185240-06-5 - O OP086 H Desoxycarbadox N’-[1-Quinoxalin-2-yl- 50 mg N N O meth-(E)-ylidene]- N CH3 100 mg hydrazinecarboxylic acid O 55456-55-8 N methylester

OP087 H Desoxycarbadox-D3 N’-[1-Quinoxalin-2-yl- 25 mg N N O meth-(E)-ylidene]- N CD3 50 mg hydrazinecarboxylic acid O 1448350-02-4 N methyl-D3-ester

OP089 O- 4-Desoxycarbadox N’-[1-(1-Oxy-quinoxalin- 25 mg H N+ N O 2-yl)-methylidene]-hydra- 50 mg N CH zinecarboxylic acid 3 O methyl ester N 118828-84-5 OP090 H 1-Desoxycarbadox N’-[1-(4-Oxy-quinoxalin- 25 mg N N O 2-yl)-methylidene]-hydra- N CH3 50 mg zinecarboxylic acid O N+ methyl ester 118828-83-4 O- OP169 Cyadox 2-Cyano acetic acid-2- 10 mg [(1,4-dioxido-2-quinox- 25 mg alinyl)methylene]hydra-

zide 65884-46-0

OP170 Cyadox-13C6 2-Cyano acetic acid-2- 10 mg [(1,4-dioxido-2-quinox- 20 mg alinyl-13C )methyle- 6 ne]hydrazide -

OP026 O CD3 2-Isopropyl-D7- 2-Isopropyl-D7- 50 mg D thioxanthen-9-one thioxanthen-9-one 100 mg CD 3 Isopropylthioxanthon- S D7 (ITX-D7) 1173019-24-3

WITEGA Laboratorien Berlin-Adlershof GmbH page 78 of 87 Other Products

OP036 CH3 Acetamiprid-N- N-Cyano-N’-[(6-chloro- 50 mg desmethyl pyridin-3-yl)methyl]- N N CN 100 mg H acetamidine Cl N 190604-92-3

OP037 NH HCl Robenidine-D8 1,3-Bis[(4-chloroben- 25 mg N N hydrochloride zylidene)amino]guani- N N 50 mg H H dine-D8 hydrochloride D D D D

D D D D 1173097-77-2 Cl Cl OP039 O Atenolol-D7 2-[4-(2-Hydroxy-3-iso- 25 mg NH propyl-D7-aminoprop- 50 mg 2 oxy)-phenyl]-acetamide

OH H O N CD3 D 1202864-50-3 CD 3

D3C OP108 D Metoprolol-D7 1-Isopropylamino-D7-3- 25 mg O N CD3 hemitartrate [p-(β-methoxyethyl)- 50 mg H OH phenoxy]-propan-2-ol OH (+)-hemitartrate salt 0.5 HOOC - COOH OH O H3C OP049 Penbutolol 1-tert-Butylamino-3-(2- 25 mg HCl hydrochloride cyclopentylphenoxy)- 50 mg OH propan-2-ol H O N CH hydrochloride 3 CH CH 3 3 28163-36-2 tert OP080 HCl Penbutolol-D9 1- -Butylamino-D9-3- 10 mg hydrochloride (2-cyclopentylphenoxy)- 25 mg OH propan-2-ol H O N CD hydrochloride 3 CD CD 3 1346605-01-3 3 OH OP126 H Sotalol-D7 hydrochlo- N-[4-[1-Hydroxy-2- 10 mg D ride (isopropyl-D -amino)- N CD 7 25 mg 3 ethyl]phenyl]methanesul- O O S CD3 fonamide hydrochloride H3C N 1398065-65-0 H HCl OH OP125 H Sotalol hydrochloride N-[4-[1-Hydroxy-2- 25 mg N CH3 (isopropylamino)ethyl]- 50 mg O O phenyl]methanesulfon-

S CH3 amide hydrochloride H3C N 959-24-0 H HCl

WITEGA Laboratorien Berlin-Adlershof GmbH page 79 of 87 Other Products OP041 Benzylpenicilline-D7 (2S-(2,5,6))-3,3- 50 mg N-ethylpiperidinium Dimethyl-7-oxo-6- + 100 mg N D salt D D H phenylacetyl-D7-amino- D O Penicillin G-D7 salt 4-thia-1-aza- CH3 H bicyclo[3.2.0]heptane-2- HN CH S 3 D D carboxylate 1-ethyl- CH 3 D N piperidinium O O O 1217445-37-8

OP044 NH2 Arprinocid 9-(2-Chloro-6-fluoro- 25 mg benzyl)-9H-purin-6- N 50 mg N ylamine F 100 mg N N

55779-18-5 Cl

OP105 O NH2 Zoalene-D5 2-Methyl-3,5-dinitrobenz- 25 mg D (Dinitolmide-D5) amide-D D D 5 50 mg D

O2N NO2 D 1596379-06-4

OP055 O NH2 3-ANOT 3-Amino-2-methyl-5- 25 mg nitro-benzamide 50 mg CH3

O N NH 3572-44-9 2 2

OP056 O NH2 5-ANOT 5-Amino-2-methyl-3- 25 mg nitro-benzamide 50 mg CH3

H N NO 90223-31-7 2 2

OP061 NH2 Melamine-13C3 [1,3,5]Triazine-2,4,6- 10 mg 13 13 C triamine-2,4,6- C3 25 mg N N 50 mg 13C 13C H N N NH 1173022-88-2 2 2 OP062 OH Cyanuric acid-13C3 [1,3,5]Triazine-2,4,6-triol- 10 mg 13C 2,4,6-13C N N 3 25 mg 13C 13C 50 mg HO N OH 201996-37-4 OP097 Cl 6-Chloro-2,4-diamino- 6-Chloro-[1,3,5]triazine- 10 mg 13 13 C 1,3,5-triazine-13C3 C3-2,4-diamine 25 mg N N

13C 13C 50 mg H2N N NH2 1216850-33-7

OP098 NH2 Ammelide-13C3 6-Amino-[1,3,5]triazine- 10 mg 13 13 C C3-2,4-diol 25 mg N N 50 mg 13C 13C HO N OH 1173021-81-2

WITEGA Laboratorien Berlin-Adlershof GmbH page 80 of 87 Other Products OP120 Cyromazine-13C3 N-Cyclopropyl-1,3,5-tria- 10 mg 13 HN zin- C3-2,4,6-triamin 20 mg 13C N N

13C 13C H2N N NH2 1808990-94-4

OP064 H2N N Baquiloprim-D6 5-(8-Dimethylamino-D6- 10 mg 7-methyl-quinolin-5- 25 mg N ylmethyl)-pyrimidine-2,4-

diamine NH2

H3C N D N D D D 1228182-50-0 D D

OP069 H2N N NH2 Baquiloprim 5-(8-Dimethylamino-7- 25 mg methyl-quinolin-5- 50 mg N ylmethyl)-pyrimidine-2,4-

diamine

H3C N N 102280-35-3 H3C CH3 OP067 CH3 GW 501516 {2-Methyl-4-[4-methyl-2- 50 mg N CH3 S (4-trifluoromethyl- 100 mg S COOH O phenyl)-thiazol-5- F3C ylmethylsulfanyl]- 317318-70-0 phenoxy}-acetic acid

13 13 OP068 CH3 GW 501516-13C4 {2-Methyl-4-[4- C- 25 mg N 13C CH3 S 13C methyl-2-(4- 13C 50 mg S COOH F3C H H O trifluoromethyl-phenyl)- 13 13 4,5- C2-thiazol-5-yl- C- - methylsulfanyl]- phenoxy}-acetic acid

OP070 NH2 Trimethoprim-D9 5-(3,4,5-Trimethoxy-D9- 25 mg O benzyl)-pyrimidine-2,4- 50 mg N CD3 diamine

H2N N O O CD3 1189460-62-5 D3C

OP157 Diaveridine-D6 5-(3,4-Dimethoxy-D6- 25 mg benzyl)-2,4-pyrimidine- 50 mg diamine

OP071 D 2’,4’-Formoxylidide-D6 N-(2,4-Dimethyl-D - 25 mg D D 6 H phenyl)-formamide 50 mg H N

O D D - D

WITEGA Laboratorien Berlin-Adlershof GmbH page 81 of 87 Other Products OP072 CH Dichloroisoeverninic 3,5-Dichloro-4-hydroxy- 25 mg O O 3 acid 2-methoxy-6-methyl- 50 mg Cl benzoic acid HO

H C OH 3 4101-80-8 Cl OP074 COOH Dichloroisoeverninic 3,5-Dichloro-4-hydroxy- 25 mg

D3C O acid-D6 2-methoxy-D3-6-methyl- 50 mg CD 3 D3-benzoic acid Cl Cl OH - OP082 H O OH Halofuginone-13C6 DL-trans-7-Bromo-6- 10 mg Cl 13C hydrobromide chloro-3-[3-(3-hydroxy- 13C 13C N 20 mg piperidin-2-yl)-2-oxo- 13C 13C O HN Br 13C N propyl]-3H-quinazoline- 13 H HBr 4-one- C6 hydrobromide - OP078 O OH Halofuginone hydro- DL-trans-7-Bromo-6- 10 mg Cl N bromide chloro-3-[3-(3-hydroxy- 25 mg O HN piperidin-2-yl)-2-oxo- Br N propyl]-3H-quinazolin-4- 64924-67-0 HBr one hydrobromide OP083 D D Ethopabate-D5 Methyl 4-(acetylamino)- 50 mg D O O 2-ethoxy-D5-benzoate 100 mg D H C D 3 O O

N CH H 3 -

O D D OP084 D D Palmitic acid glycidyl- Hexadecanoic acid 10 mg O D ester-D5 oxiranylmethyl-D ester O 5 25 mg 1794941-80-2

O D D OP085 D Stearic acid glycidyl- Octadecanoic acid 10 mg O D O D ester-D5 oxiranylmethyl-D5 ester 25 mg 1346598-19-3

OP088 H2N N NH2 Descyclopropyldicy- 2,4,6-Triamino-pyrimidi- 25 mg clanil ne-5-carbonitrile N 50 mg CN NH2 465531-97-9

15 15 15 OP091 H2 N N NH2 Descyclopropyldicy- 2,4,6-Triamino- N3- 10 mg clanil-15N3 pyrimidine-5-carbonitrile N 25 mg CN 15 NH2 -

13 OP094 D3 C CH3 Griseofulvin-13CD3 [7-Chloro-6-methoxy-4- 10 mg O O O 13 (methoxy- C,D3)- 25 mg benzofuran-3-on]-2-

O spiro-1´-(2´-methoxy-6´- H3C O O 1329612-29-4 methyl-cyclohex-2´-en- H C 4´-one) Cl 3 OP150 NH Dicyandiamide 1-Cyano-guanidine 100 mg C C N H2N N H 461-58-5

WITEGA Laboratorien Berlin-Adlershof GmbH page 82 of 87 Other Products 13 15 15 Dicyandiamide- C2, N2 OP096 NH 15 Dicyandiamide- 13 15 10 mg 13 13 N 1-Cyano- C, N-guanidi- 13C2,15N2 13 15 25 mg C C ne- C, N H2N N - H 50 mg OP166 Metformin hydrochlo- 1,1-Dimethylbiguanide 10 mg ride hydrochloride

1115-70-4

OP167 Metformin-D6 hydro- 1,1-Dimethyl-D6-biguani- 10 mg de hydrochloride chloride 25 mg

1185166-01-1 F 13 OP099 Diflubenzuron-13C6 1-(4-Chloro-phenyl- C6)- 10 mg O H H 3-(2,6-difluoro-benzoyl)- 25 mg O 13 13 urea HN C C F HN 13C 13C Cl 13C 13C 1581694-97-4 H H OP101 O 2-Methyl-4-isothiazo- 2-Methyl-isothiazolin-3- 50 mg lin-3-one one hydrochloride H C 100 mg 3 N hydrochloride S HCl 26172-54-3

OP102 O 2-Methyl-D3-4-isothia- 2-Methyl-D3-isothiazolin- 25 mg zolin-3-one 3-one hydrochloride D C 50 mg 3 N hydrochloride S HCl 1329509-49-0 OP162 4,5-Dichloro-2-methyl- 4,5-Dichloro-2-methyl-4- 10 mg 4-isothiazolin-3-one isothiazolin-3-one

26542-23-4 OP103 HO Retronecine (1R,7aR)-7-Hydroxy- 10 mg HO H methyl-2,3,5,7a-tetra- 25 mg hydro-1H-pyrrolizin-1-ol

N 480-85-3 OP104 Cl Ketamine-D3 2-(2-Chlorophenyl)-2- 10 mg O hydrochloride (methyl-D3-amino)-cyclo- 25 mg hexanone hydrochloride HN 1073254-49-5 CD 3 HCl OP106 OH Glucosylisomaltol 1-[3-(α-D-Glucopyrano- 50 mg O syloxy)-2-furanyl]-1- 100 mg HO O ethanone HO CH3 OH 3-O-α-D-Glucopyrano- O O syloxy-2-furyl methyl 85559-61-1 ketone

OP107 CD3 Propranolol-D7 1-Isopropylamino-D7-3- 25 mg D hydrochloride (naphthalen-1-yl-oxy)- 50 mg O N CD3 propan-2-ol hydrochlo- H OH ride

HCl -

WITEGA Laboratorien Berlin-Adlershof GmbH page 83 of 87 Other Products OP109 HO O 3-Phenoxy-13C6- 3-Phenoxy-13C -benzoic 25 mg H 6 benzoic acid acid 50 mg H 13C H 13C 13C (Permethrin metabo- 13C 13C lite) 13 O C H H 1793055-05-6

OP148 D3C CD3 trans-Permethric acid- (1RS,3SR)-3-(2,2-Di- 10 mg Cl D6 (metabolite of Per- chlorovinyl)-2,2-dimethyl- 25 mg OH 3 1 methrin trans-DCCA- D6-cyclopropane Cl D6, Cypermethrin, carboxylic acid (mixture O (1RS, 3SR) Cyfluthrin) of enantiomers) - 13 OP110 H O Acrylamide-1,2,3- Acrylamide-1,2,3- C3 5 mg 13C 13C 13C3 10 mg 13 H C NH2 287399-26-2 H

OP111 O (±)-Nicotine-D3 1-(Methyl-D3)-2-(3-pyri- 25 mg salicylate dyl)-pyrrolidine salicylate 50 mg N OH salt CD 3 N OH 1173021-00-5

OP116 S Methimazole-D3 1-Methyl-D3-3H-imida- 10 mg D C zole-2-thione 25 mg 3 N NH 1160932-07-9 OP124 S 2-Thiouracil-13C,15N2 2-Thioxo-2,3-dihydro-1H- 10 mg 13 13 15 C15 pyrimidin-4-one-2- C- 20 mg H N NH 1,3-15N - 2 O OP117 S 6-Phenyl-2-thiouracil- 6-Phenyl-2-thioxo-2,3- 10 mg 13 15 C15 13C,15N2 dihydropyrimidin-4(1H)- H N NH 13 15 20 mg one- C, N2 O - OP118 S 6-Propyl-2-thiouracil- 6-Propyl-2-thioxo-tetra- 10 mg H 13C 15 15 H 13C,15N2 hydropyrimidin-4-one- N N 13 15 20 mg C, N2 H3C O - OP119 S 6-Methyl-2-thiouracil- 6-Methyl-2-thioxo-tetrahy- 10 mg 13 13 15 H C H 13C,15N2 dropyrimidin-4-one- C, N2 15N 15N 20 mg

H3C O - OP121 CH3 Ethoxyquin-HCl 6-Ethoxy-1,2-dihydro- 50 mg O 2,2,4-trimethyl quinoline 100 mg hydrochloride

CH3

HN HCl 3659-01-6 H3C CH3

WITEGA Laboratorien Berlin-Adlershof GmbH page 84 of 87 Other Products

CD OP122 3 Ethoxyquin-D5-HCl 6-Ethoxy-D5-1,2-dihydro- 10 mg D O 2,2,4-trimethyl quinoline 25 mg D hydrochloride

CH3

HN HCl - H3C CH3

OP144 CH3 Ethoxyquin-Dimer 6,6’-Diethoxy-2,2,2’,2’, 10 mg

O 4,4’-hexamethyl-2H-1’,2’- 25 mg dihydro-1,8’-biquinoline

H3C CH3 CH3 N

HN H3C H3C CH3

CH3 74681-77-9

OP127 CH3 4-(3,6-Dimethylhept-3- 4-(3,6-Dimethylhept-3- 20 mg CH 3 yl)phenol yl)phenol H C CH 3 3

OH 142731-63-3

OP128 CH3 4-(3,6-Dimethylhept-3- 4-(3,6-Dimethylhept-3- 10 mg CH3 13 yl)phenol-13C6 yl)phenol- C6 H C CH 3 3 H 13C H 13C 13C 13C 13C H 13C H OH 1173020-38-6 OP129 D D Rhodamine B-D20 [9-(2-Carboxyphenyl)-6- 10 mg D3C D D CD3 Cl diethyl-D10-amino-3- 25 mg D C N O N CD 3 3 xanthenylidene]-diethyl- D D D -ammonium chloride D D 10

COOH

D OP130 Mephenytoin-D8 (±)-5-Ethyl-3-methyl-D3- 25 mg D D 5-phenyl-D5-imidazoli- CH 50 mg 3 dine-2,4-dione

D NH D O O N - CD3 D OP131 Nirvanol-D5 (±)-5-Ethyl-5-phenyl-D5- 25 mg D D imidazolidine-2,4-dione 50 mg CH3

D NH

D O O N H 119458-27-4

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CH OP132 3 H D D Lidocaine-D10 2-(Diethyl-D10-amino)-N- 25 mg N (2,6-dimethylphenyl) N CD 50 mg 3 acetamide O CH3 D CD3 D 851528-09-1

OP134 CD3 2,4,6-Trichloroanisole- 2,4,6-Trichloroanisole-D 20 mg O 5 D5 Cl Cl

D D

Cl 352439-08-8 OP135 HO D 3-MCPD-D5 3-Chloropropane-1,2- 20 mg HO Cl diole-D5 D D D D 342611-01-2 OP136 O Adapalene-D3 6-(3-Adamantan-1-yl-4- 20 mg methoxy-D -phenyl) OH 3 naphthalene-2-carboxylic

acid

D3C O

1276433-89-6

OP137 CH3 Disperse Yellow 3-D3 N-[4-(2-Hydroxy-5- 20 mg metyhl phenyl azo)phe- N nyl]acetamide-D3 HN N D3C HO O 947601-96-9

D OP138 Etofenprox-D5 2-[(4-Ethoxy-D5-phenyl)- 20 mg O D D 2-methyl propyl]-3-phen- O D D oxy-benzyl ether O H3C CH3 -

OP139 O CH3 2-Isopropyl-thioxan- 2-Isopropyl-thioxanthen- 20 mg then-9-one 9-one CH 3 S 5495-84-1 OP140 O 4-Isopropylthioxan- 4-Isopropyl-thioxanthen- 20 mg then-9-one 9-one

H3C CH3 83846-86-0 OP141 H DTPD N,N’-Di-p-tolyl-p-pheny- 20 mg N CH3 lene-diamine

H3C N H 620-91-7

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OP142 HO Disperse Red 1-D3 2-{Ethyl-D3-[4-(4-nitrophe- 20 mg nylazo)-phenyl]-amino}- N N ethanol

D3C N NO2 947601-97-0

H OP143 O OH Pimaricin (Natamycin) (8E,14E,16E,18E,20E)(1R, 50 mg O OH 3S,5R,7R,12R,22R,24S,25 100 mg R,26S)-22-(3-Amino-3,6- H3C O H OH O OH didesoxy-β-D-mannopy- O ranosyloxy)-1,3,26- trihydroxy-12-methyl-10- O O oxo-6,11,28-trioxatri-

cyclo[22.3.1.05,7]octacosa- HO OH 8,14,16,18,20-pentaene-25- NH 2 carboxylic acid 7681-93-8

O OP145 N 2-Acetamido-5-nitro- N-(5-Nitro-2-thiazolyl) 20 mg thiazole acetamide O N 2 S N H 140-40-9 OP133 O Estragol-N-Acetylcys- (E)-N-Acetyl-S-[3-(4- 5 mg 13 CH2 13C S 13CH OH tein-13C3,15N methoxy phenyl) allyl]-L- 13 15 10 mg cysteine- C3, N H3C 15 O NH - O

OP153 HO H3C Hexestrol meso-3,4-Bis(4-hydroxy- 100 mg phenyl)hexan

84-16-2 CH3 OH

OP154 HO D3C Hexestrol-D6 meso-3,4-Bis(4-hydroxy- 10 mg phenyl)hexan- 25 mg 1,1,1,6,6,6-D 6 103244-14-0 CD3 OH OP075 Amitraz Metabolite N-(2,4-Dimethyl-phenyl)- 50 mg BTS 27271 N’-methyl-formamidine 100 mg

33089-74-6 OP076 Amitraz Metabolite-D3 N-(2,4-Dimethyl-phenyl)- 50 mg BTS 27271 N’-methyl-D3-form- 100 mg amidine 1255517-75-9

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