Memorias del Primer Congreso Internacional de Revista peruana de biología 27(1): 005 - 014 (2020) doi: http://dx.doi.org/10.15381/rpb.v27i1.17624 Biotecnología e innovación - ICBi 2018 ISSN-L 1561-0837; eISSN: 1727-9933 Universidad Nacional Mayor de San Marcos Meeting Report of the First International Congress of Biotechnology and innovation - ICBi 2018 Trabajos presentados al I Congreso Internacional de Biotecnología e innovación (ICBi), 9 - 12 de julio de 2018, Universidad Nacional Agraria La Molina, Lima, Perú. The First International Congress of Biotechnology and Innovation, Editoras: Ilanit Samolski held in Lima- Peru from July 9 to 12, 2018, was organized by the La- Maria Lucila Hernández-Macedo boratory of Mycology and Biotechnology “Marcel Gutiérrez-Correa” Gretty Katherina Villena (LMB-MGC) of La Molina National Agrarian University (UNALM). Organizing Committee Autores President: Gretty K. Villena, Ph.D. in Biological Sciences and Gretty K. Villena * Engineering, https://orcid.org/0000-0001-8123-3559 [email protected] https://orcid.org/0000-0001-8123-3559 Vice-President: Ilanit Samolski, Ph.D. in Biotechnology, Maria Lucila Hernández- Macedo https://orcid.org/0000-0002-1883-7795 [email protected] https://orcid.org/0000-0003-1050-9807 Secretary: Maria Lucila Hernández Macedo, Ph.D. in Cellular Ilanit Samolski and Structural Biology, https://orcid.org/0000-0003-1050- [email protected] 9807 https://orcid.org/0000-0002-1883-7795 Correspondencia Scientific Committee *Corresponding author Universidad Nacional Agraria La Molina *President, ICBi 2018 Laboratorio de Micología y Biotecnología "Marcel Ana Kitazono Sugahara, Ph.D. in Pharmaceutical Sciences and Gutiérrez-Correa" (LMB-MGC), Facultad de Ciencias, Biotechnology, https://orcid.org/0000-0002-6924-1799 Universidad Nacional Agraria La Molina, Lima 12, Perú. Tel: +511 6147800 – 463 Ernesto Ormeño Orrillo, Ph.D. in Sciences, https://orcid. Citación org/0000-0001-8210-2497 Villena GK, Hernández- Macedo ML, Samolski I. Gastón Zolla Benitez, Ph.D. in Plant Biology, https://orcid. 2020. Meeting Report of the First Interna- tional Congress of Biotechnology and Inno- org/0000-0002-0432-1050 vation - ICBi 2018. I Congreso Internacional Gustavo Gutiérrez Reynoso, Ph.D. in Animal Breeding and Ge- de Biotecnología e innovación (ICBi), Revista peruana de biología número especial 27(1): netics, https://orcid.org/0000-0002-1896-0048 005 - 014 (Marzo 2020). doi: http://dx.doi. Julio Solis Sarmiento, Ph D. in Plant, Environmental Manage- org/10.15381/rpb.v27i1.17624 ment and soil Sciences, https://orcid.org/0000-0001-5183- 6332 Patricia Gil Kodaka, Ph.D. in Agriculture and Fisheries Scien- ces, https://orcid.org/0000-0002-8448-7893 ​Raúl Blas Sevillano, Ph.D. in Biological Engineering and Agro- nomic Sciences, https://orcid.org/0000-0003-3378-4035 Rosa A. Espejo Joya, Ph.D. in Biology, https://orcid.org/0000- 0003-3436-7516 Rosana Sonia Chirinos Gallardo, Ph.D. in Biological Enginee- ring and Agronomic Sciences, https://orcid.org/0000-0002- 9045-7471 Universidad Nacional Mayor de San Marcos Pablo Ramírez Roca, Ph.D. in Sciences, https://orcid.org/0000- 0001-9309-7021 Ruth Hortensia García de La Guarda, Ph(c) in Biological Scien- ces, https://orcid.org/0000-0003-4801-5642

Journal home page: http://revistasinvestigacion.unmsm.edu.pe/index.php/rpb/index © Los autores. Este artículo es publicado por la Revista Peruana de Biología de la Facultad de Ciencias Biológicas, Universidad Nacional Mayor de San Marcos. Este es un artículo de acceso abierto, distribuido bajo los términos de la Licencia Creative Commons Atribución-NoComercial- CompartirIgual 4.0 Internacional.(http://creativecommons.org/licenses/by-nc-sa/4.0/), que permite el uso no comercial, distribución y reproducción en cualquier medio, siempre que la obra original sea debidamente citada. Para uso comercial, por favor póngase en contacto con revistaperuana. [email protected].

005 Villena et al.

Pontificia Universidad Católica del Perú cation: i) Agricultural and Animal Biotechnology and ii) Industrial and Environmental Biotechnology. The third Alfredo Ibáñez Gabilondo, Ph.D. in Biology, section covered different Molecular Tools Applied to Bio- https://orcid.org/0000-0001-9206-1537 technology Innovation Fanny Lys Casado Peña, Ph.D. in Toxicology, in Biotechnology in the region. https://orcid.org/0000-0002-8791-626X and, finally, the fourth focused on The Congress not only sought to promote Biotechno- Universidad Peruana Cayetano Heredia logy and Innovation in Peru, but also to contribute to the Daniel Guerra Giraldez, Ph.D. in Biomedical interaction with researchers and innovators from other Sciences, https://orcid.org/0000-0002-2410- countries. Therefore, the four sections included diverse 722X conferences offered by about 50 scientists and specialists from 14 different countries (Appendix 1). Each section Universidad Católica Santa María was closed with a Round Table focused on discuss the Lena Gálvez Ranilla, Ph.D. in Food Sciences, Current Situation and Perspectives of the area in Peru. https://orcid.org/0000-0002-7261-3303 Participants University of Minnesota ICBi 2018 was attended by 150 registered partici- Federico Abel Ponce de León, Ph.D. in Genetics, pants from various countries such as Peru, Brazil, Chile https://orcid.org/0000-0001-8645-553X and Bolivia. Participants presented 37 Oral Communi- cations and 44 Posters which were grouped according Universidade Tiradentes Jorge Alberto López, Ph.D. in Sciences, https:// best oral communications and posters were awarded. orcid.org/0000-0003-1214-7619 to the first 3 sections (Supplementary material S1). The Theoretical-Practical Courses University of Erlangen-Nuremberg - Jorge L. Wong Dávila, Ph.D. in Biological Enginee- ses were offered before and after the Congress, with A total of five specialized theoretical-practical cour ring, https://orcid.org/0000-0001-9211-8652 approximately 20 participants per course: i) Analysis of Transcriptomic data: RNA-Seq, ii) Bioprospecting of Soil Evaluation Panel Microorganisms, iii) Applications of Raman – AFM Micros- Oral Communications: copy, iv) Gene Editing in Fungi and Yeasts: CRISPR-Cas9 and v) Metagenomics: Identifications of OTUs by Illumina Julio Solis, Maria Lucila Hernández-Macedo, Gretty K. Next Generation Sequencing Technology (Table 1). Villena, Dr. Ilanit Samolski, Yvette Ludeña, Milagros Chang. Financing and Sponsorship Posters: Most of the budget to carry out ICBi 2018 came from the registration fees of the participants. Support was - also received from 17 companies and an NGO, which had ge Alberto López. the opportunity to show their products and services on Patricia Gil-Kodaka, Marcelo da Costa Mendonҫa, Jor stands (Table 2). Scientific Program

- fferentThe biotechnologicalscientific program areas (Appendix according 1) was to dividedtheir appli into- four sections. The first two sections corresponded to di

Table 1. Specialized Courses offered by ICBi 2018 Duration Course Specialist Affiliation (days)

Analysis of Transcriptomic data: RNA-Seq 2 MSc. Hugo Valdivia BioScience App (Peru)

Dr. Doris Zuñiga, Dr. Marcia Toro, Dr. Er- Laboratory of Microbial Ecology and Bio- Bioprospecting of Soil Microorganisms 3 nesto Ormeño, Dr. Katty Ogata technology (LEMYB-UNALM)

Applications of Raman – AFM Microscopy 1 Dr. Fernando Vargas Witec (Germany)

Washington State University, Technical Gene Editing in Fungi and Yeasts: CRISPR-Cas9 2 Dr. John Wyrick , Dr. Jakob Blæsbjerb University of Denmark

Metagenomics: Identifications of OTUs by Illu- 5 Guillermo Trujillo GenLab del Perú mina Next Generation Sequencing Technology

006 Rev. peru. biol. 27(1): 006 - 025 (Marzo 2020) Memorias del Primer Congreso Internacional de Biotecnología e innovación - ICBi 2018

Dr. Victor Meza, Faculty of Sciences - Dean Sponsors Table 2. Dr. Cesar López, Biology Department, Director Company/NGO - Ades S.A.C. (Warem S.A.C.) rector Applikon Biotechnology Inc. MSc.Dr. Ivonne Segundo Salazar, Gamarra, Institutional Social Image Extension Office -and Di Baires S.A.C. Belomed S.R.L. Biosym E.I.R.L. Projection Office - Director Peruvian Society of and Molecular Biotechnology Latina S.R.L. Academic and Scientific Sponsors Biology (SPBBM) Corporación Vasot S.A.C.

® Peruvian National Council for Science (CON- Craneando CYTEC) Ecodes ONGD National Innovation Program for Competitive- J&B Lab S.A.C. ness and Productivity (INNÓVATE PERÚ) Kossodo S.A.C. Sponsoring companies La Ensenada S.R.L. Merck Peruana S.A. Nexo Equipamiento y Servicios S.A.C. ScientificSupport Committee Committee and Evaluation Panel Proyectos Pesacon S.A.C. Adriana Elvira Mansilla Tafur, Alonso Reyes Calde- Reactivos para Análisis S.A.C. rón, Ana Belén Amaya Chuyes, Antony Barrientos Sartorius AG Zevallos, Brandon Axl Gárate Reyes, César Huallpa WITec Pte. Ltd. Robles, Felipe Huanachín Carahuanco, Fernando Guerrero Zurita, Franchescca Crevani Oré, Jan- In addition, ICBi 2018 was supported by academic nireth Guerrero Arias, Jhonathan S. Benites Pa- - riente, Katherine R. Garcia Luquillas, Leslie Diana te and Faculty of Sciences of the UNALM, the Peruvian Velarde Apaza, Liliana Rocío Rengifo Urbietta, Lo- Societyand scientific of Biochemistry sponsors suchand asMolecular Research Biology, Vice-Rectora whose rena Elizabeth Menduiña Huasanga, Luisa López members participated in the selections of the works pre- Alvarado, María Lupe Román Horna, María Mary sented, and Revista Peruana de Biología, responsible for Pasmiño Pezo, Mario David Cueva Távara, Meri- preparing a Special Number dedicated to the Congress. yim J. Carrasco, Miki Gonzáles Uscamayta, Mishell Landa Flores, Paola Finetti Casanova, Raquel Álva- Acknowledgment rez Ccoscco, Renzo Meza Florez, Teresa Damaris Organizing Committee wants to thank to. Rebaza Cárdenas, Yvette Ludeña Hinojosa. La Molina National Agrarian University authorities Luis Enrique Moyano, from i design Perú, for his great work on the web page: www.icbiperu.com Dr. Enrique Flores, Rector Dr. Carmen Velezmoro, Research Vice-Rector Dr. Jorge Alarcón Academic Vice-Rector

Rev. peru. biol. 27(1): 007 - 025 (March 2020) 007 Villena et al.

Appendix 1

Academic and Scientific Sponsors:

Revista Peruana de Sociedad Peruana de Bioquímica y Biología Molecular Biología & Biotechnology VICERRECTORADO DE INVESTIGACIÓN

Sponsors:

Agricultural Biotechnology BIOTECNOLOGY Animal Biotechnology LATINA S.R.L Industrial Biotechnology Environmental Biotechnology Molecular tools Innovation in Biotechnology

PROGRAMME ICBi 2018

With the support of:

PROGRAMME 17:15 - 18:00 Homage Round Table “Marcel Gutiérrez Correa and Biotechnology in Peru” Main Auditorium of UNALM Dr. Ernesto Bustamante Dr. David Campos, Universidad Nacional Agraria La Molina Monday, July 9 Dr. José Luis Bauer, Universidad Peruana Cayetano Heredia Dr. Gianangelo Nava 9:00 - 10:00 Registration 18:00 Official Ceremony of Inauguration by the authorities of UNALM 10:00 - 10:30 Welcoming words from the President of Organizing Committee Words from the Rector, Dr. Enrique Flores Mariazza Dr. Gretty Villena Cultural act and welcoming cocktail

Section I: Agricultural and Animal Biotechnology Tuesday, july 10

10:30 - 11:15 Keynote Conference “Genome editing in crop improvement” Dr. Paul Chavarriaga Section II: Industrial and Environmental Biotechnology Centro Internacional de Agricultura Tropical (CIAT), Colombia 11:15 - 11:35 Coffee break 9:30 - 10:15 Keynote Conference “Challenges in the implementation of agro-industry by-products 11:35 - 12:05 “Use of genomics in animal breeding and improvement” based bio-refineries” Dr. Mario Poli Dr. José Texeira Instituto Nacional de Tecnología Agropecuaria (INTA), Argentina Univeridade do Minho (UMinho), Portugal 12:05 - 12:35 “Evaluation and regulation of genetically modified organisms in Latin America. 10:15 - 10:45 “Wastewater treatment and value-added compounds production” Considerations” Dr. Mario Kato Dr. Eduardo Menéndez, Spain 12:35 - 13:30 Lunch Universidade Federal de Pernambuco (UFPE), Brazil 13:30 - 14:00 “Biotechnological advanaces in animal reproduction and genetic improvement” 10:45 - 11:20 “Ureide as a novel target to improve abiotic stress resistance in plants” Dr. William Vivanco Dr. Christopher D. Todd Universidad Nacional Agraria La Molina (UNALM), Peru University of Saskatchewan (Usask), Canada 14:00 - 14:30 “Genomics of phytopathogenic viruses” 11:20 - 11:40 Coffee break Dr. Jan Kreuze Centro Internacional de la Papa (CIP), Peru 11:40 - 12:10 “Use of macroalgae for bioremediation and its biotechnology uses” 14:30 - 15:00 “Biotechnological tools for Fusarium wilt study” Dr. Loretto Contreras Dr. Mauricio Luna Universidad Andrés Bello (UNAB), Chile Universidad Veracruzana (UV), Mexico 12:10 - 13:00 Round Table: Current situation and perspectives of industrial and environmetal 15:00 - 15:45 Round Table: Current situation and perspectives of agricultural and animal biotechnology biotechnology in Peru in Peru Dr. Gustavo Gutiérrez, Universidad Nacional Agraria La Molina (UNALM) Dr. Patricia Gil, Universidad Nacional Agraria La Molina (UNALM) Dra. Martha Valdivia, Universidad Nacional Mayor de San Marcos (UNMSM) Dr. David Campos, Universidad Nacional Agraria La Molina (UNALM) Dr. César López, Universidad Nacional Agraria La Molina (UNALM) Dr. Pablo Ramírez, Universidad Nacional Mayor de San Marcos (UNMSM) Dr. William Roca, Asociación Peruana para el Desarrollo de la Biotecnología (PeruBiotec) Dr. Víctor Meza, Universidad Nacional Agraria La Molina (UNALM) 15:45 - 16:05 Coffee break 13:00 - 14:00 Lunch 14:00 - 14:45 Keynote Conference of Intellectual Property “Patents: managment and administration in Section II: Industrial and Environmental Biotechnology biotechnological products” Mg. Stephany Soto 16:05 - 16:35 Keynote Conference “Biorefineries based on microalgae for bioactive compounds production” MERTZ, Peru Dr. Roberto T. Abdala 14:45 - 16:00 Oral Presentations: Universidad de Málaga (UMA), España Agricultural and Animal Biotechnology, Auxiliary Room 1 16:35 - 17:15 “Bioethanol: the brazilian experience” Industrial and Environmental Biotechnology, Main Auditorium Dr. Carlos Alberto Labate Molecular Tools Applied to Biotechnology, Auxiliary Room 3 Universidade de São Paulo (USP), Brazil

008 Rev. peru. biol. 27(1): 008 - 025 (Marzo 2020) Memorias del Primer Congreso Internacional de Biotecnología e innovación - ICBi 2018

16:00 - 16:20 Coffee break 15:40 - 16:10 “Single nucleic molecule real-time sequencing (SMRT) to characterize specific transcripts 16:20 - 18:10 Oral Presentations: and alleles of alternative mRNA splicing” Agricultural and Animal Biotechnology, Auxiliary Room 1 Dr. Abel Ponce de León Industrial and Environmental Biotechnology, Main Auditorium University of Minnesota (UMN), USA Molecular Tools Applied to Biotechnology, Auxiliary Room 3 16:10 - 16:25 Coffee break

Wednesday, july 11 Section IV: Innovation in Biotechnology

Section III: Molecular Tools Applied to Biotechnology 16:25 - 17:05 Keynote Conference “The interface research and commercial production of entomopathogenic fungi for the biological control of pests” 09:30 - 10:15 Keynote Conference “New tools for multiplexed immunofluorescence: More colors and Dr. Marcelo da Costa more dimensions, faster and easier” Universidade Tiradentes (UNIT), Brazil 17:05 - 17:35 “Development of molecular tools by in vitro evolution technologies” Dr. Stephen Kron Dr. Pohl Milón University of Chicago (UCHI), USA Biodynamols, Peru 10:15 - 10:45 “Gene edition & yeasts” 17:35 - 18:35 Official posters exhibition* Dr. John Wyrick External environment Washington State University (WSU), USA Agricultural and Animal Biotechnology (BAA) 10:45 - 11:05 Coffee break Industrial and Environmetal Biotechnology (BIA) 11:05 - 11:35 “Characterization of (Meta)genomes structure and dynamics using high-throughput Molecular Tools Applied to Biotechnology (HMB) chromosome conformation capture data” * Posters can be displayed from the first day of the Congress Dr. Martial Marbouty Centre National de la Recherche Scientifique (CNRS), France Thursday, july 12 11:35 - 12:05 “Utilization of CRISPR-Cas9 for elucidating secondary metabolism in filamentous fungi” Dr. Jakob Blæsbjerg Section IV: Innovation in Biotechnology Technical University of Denmark (DTU), Denmark 12:05 - 12:35 Keynote Conference “Whole genome sequencing in genetic medicine” 09:00 - 09:45 Keynote Conference “Platforms for biosimilars production” Dr. Elizabeth McNally Dr. Irina Mathov Northwestern University (NU), USA Sartorius, Argentina 12:35 - 13:40 Lunch 09:45 - 10:15 “Strategies for the diagnosis and prevention of avian diseases through biotechnological 13:40 - 14:10 “Correlative microscopy AFM-RAMAN in biological applications” tools” Dr. Fernando Vargas Dr. Manolo Fernández WITec, Germany Farvet, Peru 14:10 - 14:40 “Enzymatic degradation of pesticides, Degradación enzimática de pesticidas: from 10:15 - 10:45 “Scale up and optimization of bio-processes” microbiology to nanotechnology” Dr. Edgar Javier Arias Ramírez Dr. Rafael Vázquez-Duhalt Eppendorf, USA Universidad Nacional Autónoma de México (UNAM), Mexico 10:45 - 11:15 “Use of NGS and genomic indicators to certify aquaculture origin of fan shells” 14:40- 15:40 Round Table: Current situation and perspectives of the use of molecular tools applied to Dr. Mónica Santa María Biotechnology in Peru BioAl, Peru Dr. Mirko Zimic, Universidad Peruana Cayetano Heredia (UPCH) 11:15 - 11:30 Coffee break Dra. Fanny Casado, Pontificia Universidad Católica del Perú (PUCP) Dr. Alfredo Ibáñez, Pontificia Universidad Católica del Perú (PUCP)

11:30 - 12:00 “Application of enzymatic processes for the use of by-products of the fishing industry” Mg. Fernando Miranda del Solar Austral Group S.A.A., Peru 12:00 - 12:30 “Current applications of molecular markers: an opportunity for the development of knowledge and technologies in local genetic resources” Dr. Luis Eduardo Morillo Instituto Nacional de Investigaciones Agropecuarias (INIAP), Ecuador 12:30 - 13:15 “Advancing with confidence steps within protein separation processes” Dr. Carlos Bravo BioRad 13:15 - 14:15 Lunch 14:15 - 15:00 “A purification strategy for clinical grade monoclonal antibodies using hydrophobic cation exchange chromatography” Dr. Erik Victor Verona BioRad 15:00 - 15:30 “Obtaining chitin biopolymers from enzymatic microbial hydrolysis of shrimp residues” Dra. Susana Sirvas Instituto Tecnológico de la Producción (ITP), Peru 15:30 - 16:00 “Viruses in banana crops in Peru and use of IC-PCR in a participatory strategy for the production of quality seeds” Mg. Jorge Tenorio Universidad Privada Telesup, Peru 16:00 - 16:30 “Omics technologies for the study of plant-associated microbiote” Biol. Carlos Enrique Condemarín Biotecoop, Peru 16:30 - 17:00 “Industrial cultivation os spirulina: the I + D role” Biol. Biotech. Gregory Guerra Alimenta Algae, Peru 17:00 - 17:30 Round Table: Current situation and perspectives of biotechnological innovation in Peru Dr. Pohl Milón, Biodynamols Mg. Gonzalo Villarán Córdova, Instituto Tecnológico del Perú (ITP) Mg. Erich Inguil, Innóvate Perú 17:30 - 18:00 Closing Ceremony Awards to the best works Closing toast Closing Dinner

Rev. peru. biol. 27(1): 009 - 025 (March 2020) 009 Villena et al.

Appendix 2

PROGRAMA DE PRESENTACIONES ORALES Martes 10 de Julio 14:4519:30 hrs Horario Expositor Código Título Genomic and proteomic identification of lactic acid 17:15 – Lourdes Vás- OBAA54 bacteria isolated from the feces of the sajino (Pecari Sección I: Biotecnología Agrícola y Animal 17:30 quez Rojas tajacu) and metagenomic characterization Lugar: Sala Auxiliar 1– Auditorio Principal de la UNALM Metabolic Profile of avocado Persea( americana) cv. 17:30 – Félix Terán Horario Expositor Código Título OBAA63 Hass at physiological maturity from two harvest 17:45 Hilares Metagenomic characterization of the intestinal micro- seasons 14:45 – Fredy Fabian OBAA02 biome and feces of the piglet (Sus scrofa) and probiotic Karla Lucia 15:00 Domínguez 17:45 – Evaluation of the Newcastle Disease Virus–Specific T evaluation of lactic acid strains identified molecularly Álvarez OBAA66 18:00 Proliferation in Vaccinated Chickens Potato Genes Candidates for Resistance to Fernández 15:00 – German De OBAA03 Globodera pallida, identified with ARNseq in the 18:00 – Response to the inoculation of Andean Tarwi with 15:15 La Cruz Nataly Taco OBAA98 radicular transcriptome 18:15 strains of Bradyrhizobium isolated from a wild lupine Joao Adhe- 15:15 – Viruses detection in arracacha (Arracacia xanthorrhiza) mir De Souza OBAA04 Sección II: Biotecnología Industrial y Ambiental 15:30 using Next Generation Sequencing Pacheco Lugar: Auditorio Principal de la UNALM Molecular identification of the microbiota associated Horario Expositor Código Título 15:30 – Karina Zapata OBAA05 with blood and gonads of the brown shell Anadara Culturedependent and independent analysis of 15:45 Vidaurre 14:45 – Rosita Castillo tuberculosa OBIA15 bacterial community of an area contaminated and no 15:00 Rogel 15:45 – Oscar Gómez Time of conservation under refrigeration of gelified contaminated with petroleum in Nieva, Amazonas OBAA06 16:00 Quispe semen of alpaca (Vicugna pacos) Optimization of the environmental parameters of the 15:00 – Augusto Casti- Ana Luz OBIA16 fermentation ofKluyveromyces marxianus NRRLY 16:00 – GCMS analysis of Sanky (Corryocactus brevistylus 15:15 llo Calderón Nolberto OBAA07 7571 for the production of inulinase 16:45 BRITTON & ROSE), a endemic cactus from Peru. Sucahuamani Emilio Fredy 15:15 – Evaluation of physicochemical and microbiological Victor Antibiotic resistance of Salmonella sp, Escherichia coli in Yábar OBIA17 16:15 – 15:30 characteristics of tocosh during fermentation Carhuapoma OBAA08 babies of alpacas (Vicugna pacus) with and without Villanueva 16:30 De la Cruz enteropathies diarrheal Physicochemical characterization and application of 15:30 – Joselyn Matías Araya OBIA18 biochar as copper bioadsorbent generated from the Isolation and molecular characterization of sulphate 15:45 16:30 – Marilyn kelp Macrocystis pyrifera OBAA09 oxidant bacteria present in the blood of the bivalve mo- 16:45 Zavala 15:45 – Santiago Studies on the Microbial Degradation of Cyanide. A llusk Anadara tuberculosa (Sowerby 1833) "black shell" OBIA19 Arellano 16:00 Justo Arévalo Functional, Structural, and Bioinformatic approach. Preliminary results on implementation of CRISPR/Cas9 16S rRNA Next Generation Sequencing analysis 16:45 – Yoel Zegarra 16:00 – Verónica Edith OBAA14 system for WSSV receptordirected mutagenesis in OBIA20 shows microbial community associated with the gen- 17:00 Bermúdez 16:45 Liza Trujillo Litopenaeus vannamei shrimp spermatids eration of acid mine drainage in a gold mine, Peru. Effect of the inoculation of quinoapromoting bacteria in Victor Hugo Evaluation of a bioremediation system for heavy 17:00 – Juan Pauro 16:15 – OBAA48 controlled conditions isolated from Peruvian highland Sarmiento OBIA21 metals based in fungal biomass from Santuario 17:15 Roque 16:30 soils Casavilca Nacional del Ampay

Horario Expositor Código Título Horario Expositor Código Título Effect of cellulolytic action in the extraction of red drop Carlos Proteomic analysis of the cyanotrophic strain 19:30 Norma 16:30 – OBIA99 chilli carotenoids (Capsicum baccatum), Oxapampa Enrique OBIA23 Alcaligenes faecalis after its exposure to cyanide by 19:45 Gamarra 16:45 province – Peru Cubas Zúñiga MALDI TOF / TOF 16:45 – Francis More Genomic and proteomic characterization of native OBIA24 Sección III: Herramientas Moleculares Aplicadas a la Biotecnología 17:00 Calero coastal bacteria degrading petroleum hydrocabons Lugar: Sala Auxiliar 2– Auditorio Principal de la UNALM Evaluation of Chenopodium album L. (Liccha) 17:00 – Susan Sofía Horario Expositor Código Título OBIA51 phytoremediation capacity in contaminated water 17:15 Flores Calla 14:45 – María Fenanda Genetic diversity and population structure ofPersea with lead and cadmium OHMB28 15:00 Dávila Pulido Americana Mill. at northwestern Mexico Ariadna Biotechnological treatment for the deinking of 17:15 – 15:00 – Jesús Mireya Bioinformatic analysis of polyphenoloxidase coding Zatyuri Zúñiga OBIA57 printed office paper with thermostable from OHMB29 17:30 15:15 Higuera Rubio genes in avocado (Persea americana Mill). Llanos Geobacillus thermoparaffinivorans CB13 Rosalva Bioinformatic analysis of orthologs sequences to Roberto 15:15 – 17:30 – Bioprospecting of thermophilic bacteria for the bio- Carolina Valdez OHMB30 HMGR, VTE1 and VTE5 in avocado Castellanos OBIA58 15:30 17:45 technological production of thermostable enzymes Agramón (Persea americana) genes Cabrera Juan Pablo Identification of SNP molecular markers associated to Maribel Bioremediation of organic effluents from the food 15:30 – Valenzuela OHMB31 grain yield, oil and protein content for the 17:45 – Marleny industry, through a mixed system composed of a uasb 15:45 OBIA68 Apodaca development of corn hybrids in México. 18:00 Ángeles bioreactor packed with anaerobic bacteria and an Influence of vaginal birth on the content of lactic acid 15:45 – Elizabeth Llanos airlift bioreactor packed with filamentous fungi OHMB40 bacteria with probiotic potential in meconium of human Biodegradation of petroleum hydrocarbons using un- 16:00 Paitán Anticona 18:00 Mirko David neonates OBIA69 defined microbial ecosystems in submerged systems, 16:00 – Mónica Criollo Design and evaluation of DNA vaccines against the Tila 18:15 Lino Navarro OHMB43 evaluation by means of a Factorial design 16:45 Joaquín pia Lake Virus (TiLV) in Oreochromis niloticusfrom Peru Carmen Identification of cellolulolityc and xylanolytic 18:15 16:15 – OMICs; applications in pathogen diagnostic of aquatic Tamariz OBIA70 thermotolerant bacteria from Chancos hot spring and Benoit Diringer OHMB44 18:30 16:30 species cultivated in Peru. Ángeles their ability to degrade agriculture waste 16:30 – Wilfredo Evan- Difference in Long Range Communication of the Sec- Evaluation of the Hydraulic Residence Time in a MBBR OHMB56 18:30 Jimmy Capia 16:45 gelista Falcón ond PDZ domain of Protein Tyrosine Phosphatase OBIA80 bioreactor for the treatment of effluents from the Diana Pao- Metagenomic analysis of genes that code for the phe- 18:45 López 16:45 – tanning industry la López OHMB60 notype of resistance to betalactam antibiotics in a 17:00 18:45 Evaluation of mine tailings as a source of sustainable Velandia Colombian natural park Hugo Jiménez OBIA83 19:00 energy through Microbial Fuel Cells Specific allele PCR and RFLP as molecular techniques 17:00 – José Miguel 19:00 Leslie Velarde Tolerance of lignolytic basidiomycetes to chlorpyrifos OHMB71 for the diagnosis of anticonvulsant resistance in OBIA88 17:15 Carpio Carpio 19:15 Apaza and metamidophos in conditions in vitro epileptic patients Identification and characterization of cellulases from Grupos bacterianos asociados a la descomposición mi- 19:15 Norma 17:15 – Gladys OBIA97 Aspergillus niger ATCC1064 obtained in three OHMB93 crobiana de anchoveta peruana (Engraulis ringens) iden- 19:30 Gamarra 17:30 Ccahuantico fermentation systems tificados por metagenómica dirigida al gen 16S rRNA

010 Rev. peru. biol. 27(1): 010 - 025 (Marzo 2020) Memorias del Primer Congreso Internacional de Biotecnología e innovación - ICBi 2018

PROGRAMA DE PRESENTACIONES DE PÓSTERES Miércoles 11 de Julio 17:3518:35 hrs Sección II: Biotecnología Industrial y Ambiental

Sección I: Biotecnología Agrícola y Animal Expositor Código Título Potential application of commercial Corina Berrocal PBIA022 preparations for the production of Expositor Código Título isomaltooligosaccharides from maltose Quantitative variation of characters associated to ploidy Gean Ciprian Mayara Isolation and Identification of Mangrove Bacteria PBAA010 level in androgenic plants of aguaymanto PBIA026 Salcedo Almeida Lustosa Sediment with Potential Biodegradation of Petroleum (Physalis peruviana L.) Francisco Bioactive compounds from Porphyra CHF and Pyropia PBIA027 Analysis of genetic variability of Suri populations Castañeda orbicularis during natural dessiccation cycle Damaris Esquén PBAA011 (Pterocnemia pennata) in three rescue centers from Puno Bayona Joyce Mamani Chemical study of the seaweed Caulerpa filiformis and Lambayeque using microsatellite markers PBIA041 Hilasaca (chlorophyta) as a potential source of bioactive principles Susan Linares Identification of reference genes from RNAseq data in PBAA012 Synthesis of cellulose nanofibers from lignocellulosic Huapaya Lupinus mutabilis Sweet Diego Batista PBIA042 materials from industrial waste Andrea Cuba A fast and costeffective methodology for Purification of Molecular characterization of bacteria associated with the PBIA045 Natalí Ríos Castro PBAA013 microalgae Isochrysis galbana and Chaetoceros gracilis, Portocarrero cyanidedegrading enzyme from Bacillus pumillus used in the culture of the mollusk Argopecten purpuratus Miguel Montero A Cyanide Bacterial Biosensor based on Genomic editing PBIA046 Orozco of Cyn operon from Bacillus pumilus Rosalinda Arévalo Fertilization of Pijuayo with Esgoto Sludge and Potentially PBAA049 Daladier Miguel Bioelectricity from cellulolítics microbes in cell of Pinedo Toxic elements in the edible part PBIA047 Castillo Cotrina microbial fuel Jean Piere Mutagenesis at the Nterminal end of the Cry1Ab toxin of Luis David Pabón Phylogenetic and Sequencebased Analysis of PBAA050 PBIA052 Quiliche Duran Bacillus thuringiensis var. Kurstaki Rodriguez Prokaryotic Cyanide Dihydratases (CynD) Prospecting of Mangrove Bacteria with Organochlorine Carlos Eduardo "In vitro" culture of meristems of four varieties of Dianthus Jorge A. López PBIA053 PBAA062 Compound Remediation Potential caryophylus Villanueva Aguilar L. "standard carnation Judith Soledad Efficiency of biodegradation of ammonia by an isolated PBIA061 microbial consortium in a bioreactor type: Runoff filter Jesús Martín Optimization of culture medium for the production of Yangali Vicente PBAA064 Daniela Thaís A low molecular weight protein induced as a function of Guerra López biomass of Avibacterium paragallinarum PBIA065 Zapata Sifuentes cyanide concentration in a Bacillus licheniformis strain Jhakelin Gloria Postthawing quality of spermatogonial stem cells (SSC) of Design of a production medium with waste agroindustri- PBAA067 Jessi Claudio Reyes Vasquez alpaca (Vicugna pacos) proliferated in vitro PBIA074 als optimizing the capacity of mineralization of calcium Fonseca by Bacillus pseudofirmus Development of downstream purification processes of Ricardo David Tarazona Design of an artificial bioproduction microfluidic system PBAA072 recombinant glycoprotein G obtained from insect cells: PBIA075 Montesinos Jurado for protein synthesis a proof of concept Mixed culture of Aspergillus niger and Trichoderma Franchescca Silvia Agüero Bradyrhizobium sp. with high potential for phosphorus PBIA077 reesei for the production of cellulases by Surface PBAA094 Crevani Aguilar solubilization in Lupinus ass ballianus c.p Smith "jera" Adhesion Fermentation with Bolaina Blanca residues

Expositor Código Título Sección III: Herramientas Moleculares Aplicadas a la Biotecnología Influence of CO on the biomass production and total María Zadith 2 PBIA079 accumulation in four Amazonian microalgae Expositor Código Título Casuso Wong species Joshelin Huanca Plasmid library construction through in vivo cloning in Assesement of microbial diversity of the Rainbow PHMB032 Raquel Álvarez PBIA081 Juarez the yeast Saccharomyces cerevisiae Mountain in Pitumarca Peru: a preliminary report Katherin Aptamerbased biosensors for the direct detection of Assesment of biomass in mixed fungal biofilm cultures of PHMB033 Alonso Reyes PBIA082 Aspergillus niger and Trichoderma reesei through quanti- Peñaranda infectious microorganisms fication of genomic DNA content Luis Gutiérrez Genetic screening for proteins that confer resistance to Identification of candidate genes neutralalkaline PHMB034 Damaris Rebaza PBIA084 Mesias UV radiation or oxidants in Saccharomyces cerevisiae cellulases from Aspergillus fumigatus LMB35Aa Omar Melo Characterization of Aedes aegypti cultivable microbiota Screening of components for a cellulase production me- PHMB035 Brandon Gárate PBIA085 dia for Aspergillus fumigatus in a deepwell plates as a Calero by tandem mass spectrometry proteotyping submerged fermentation system An in vitro assay to identify NAD+, FAD or CoA as compo- Evaluation of different variables in the production of Raquel Merino PHMB036 Paola Finetti PBIA086 lignolytic enzymes from Guazuma sp. residues with nents of the capping structures of RNA Trametes polyzona LMBTM5 Comparison of the photoprotective effects of Comparison of the production of coloured pigments by Sandy Mansilla PHMB037 commercial sunscreens using yeast cells survivability to Liliana Rengifo PBIA087 filamentous fungi in submerged fermentation and UV irradiation surface adhesion fermentation Sodium Alginate from the kelps Macrocystis pyrifera, Identification of small peptides targeting pknG from Ana Belén Amaya PBIA089 Macrocystis integrifolia and Sargassum sp. Victor Zegarra PHMB038 Mycobacterium tuberculosis by structural and (Phaeophyceae) combinatorial biology approaches Fernando Cellulases production by Trametes polyzona on orange Ana Elena PBIA090 PHMB039 Aptamers as inhibitors of bacterial protein synthesis Guerrero waste as substrate Sánchez Katherine Garcia Gene expression analysis of cellulases in mixed fungal Cristian Genetic diversity and structure of creole goat Capra PBIA091 PHMB055 Luquillas biofilms of Trichoderma reesei and Aspergillus niger Bustamante hircus from Lima and Piura using microsatellites Production of fermentable sugars from lignocellulosic Michella Lorena Menduiña PBIA092 In silico analysis of P344R mutation in SLC17A5 explain residues with Aspergillus niger Alessandra PHMB073 defects in lysosomal transport of sialic acid Brescia Reátegui Obtaining bioethanol by enzymatic digestion of Asper- gillus niger and Bacillus subtilis in sugarcane bagasse, Influence of nitrate in the expression levels of the Acetyl Segundo Levi Meriyim Carrasco PBIA095 malt bagasse and mixture of these, in fermentation sys- PHMB076 CoA Carboxylase gene and total lipids production in Estela Moreno tems with Saccharomyces cerevisiae and Zymomonas oleaginous microalgae from the Peruvian Amazon mobilis Advances in the selection of Frost Tolerant Genotypes in Cosmeceutical Potential and Biactive Compounds of Joel Flores PHMB078 Iliana Chang PBIA096 Peruvian potato landraces (Solanum sp.) Comercial Algal Extracts of PSW SA

Rev. peru. biol. 27(1): 011 - 025 (March 2020) 011 Villena et al.

Appendix 3

Welcome to the First International Congress of Biotech- nology and Innovation, July 9 - 12, 2018 by Gretty K. Villena, President of ICBi Dear colleagues, young researchers and students It is an honor for us to welcome you to the I International Congress of Biotechnology and Innovation, ICBi 2018, organized by the National Agrarian University La Molina (UNALM) and the Laboratory of Mycology and Biotech- nology "Marcel Gutiérrez-Correa" (LMB). As a country, in recent years Peru has experienced positive economic

and innovation begin to be noticed. Certainly, the investment in Science and Technologychanges, further is not development yet comparable and the with first that efforts of other to boost Latin scientific American research coun- tries. However, we are aware that as researchers we also have a social and - ntry. Many young scientists have returned to the country and many others havemoral been commitment trained here, to the and scientific the expectations and economic for contributing development effectively of the cou to the country are enormous. The research carried out in recent years in the country is translating into innovations and ventures. We must not stop this initial advance. As a University, we have managed to prioritize research efforts and impro- ve installed capacity and infrastructure in Biotechnology. Nowadays, UNALM has modern Biotechnology Laboratories and this gives us a unique opportu- nity to join efforts in developing basic and applied Biotechnology research as development instruments and effective contribution to the productive sector. In this context, following the example and joining the efforts of our pro- fessors and mentors, we have decided to organize the First edition of the In- ternational Congress of Biotechnology and Innovation, ICBi 2018. It is time to promote Biotechnology and Innovation in Peru, it is time to promote more Welcoming words from the President of strongly the interaction between researchers and innovators in Latin Ameri- Organizing Committee Dr. Gretty Villena ca and other countries of the world. It is time to encourage new generations of researchers and students to be actively involved in the different areas of biotechnology. Also, it is a very special occasion to, through this event, pay tribute to who was a tireless researcher and promoter of Biotechnology in Peru, Dr. Marcel Gutiérrez Correa, professor at UNALM. We are motivated by the next inaugu- ration of the new building of the Laboratory of Mycology and Biotechnology that he founded, and that he could not see concluded. The LMB will be named after him and will be our best legacy. - tions of Agricultural and Animal Biotechnology, Industrial and Environmental BiotechnologyThe scientific as program well as the of ICBisection 2018 of isMolecular organized Tools in conferences used in Biotechnolo in the sec- gy. We have also included the innovation section to publicize the experiences of technological development in biotechnology in the region. The organization of this event could not be possible without the support of committed people and institutions. We appreciate the academic sponsor- ship of UNALM, the Vice-Rectorate for Research and the Faculty of Science of UNALM. CONCYTEC and Innovate who help us with networking the ICBi 2028. To the Peruvian Society of Biochemistry and for their

supportTo the in Revista the Scientific Peruana Committee. de Biología, for the academic support and endor- sement in the edition and publication of the Book of abstracts of the Congress.

012 Rev. peru. biol. 27(1): 012 - 025 (Marzo 2020) Memorias del Primer Congreso Internacional de Biotecnología e innovación - ICBi 2018

To the companies that have supported us to make this effort viable. I personally thank the Organizing Committee, the Vice President and the Secretary of the Organizing Committee of the ICBi 2018 and the Support Com- mittee for their commitment and unswerving effort in organizing this event. To our Latin American and foreign guests, we will have the pleasure of re- ceiving you in our historic capital, surrounded by archeological sites, with its colonial architecture declared a World Heritage Site by UNESCO, and its very well recognized gastronomy. Thank you very much to all of you for the effort in preparing your lectures, posters and oral presentations and for making this event a reality. Finally, we hope that this initiative will be replicated in our country or abroad and that ICBI 2021 is a reality. We will work hard on that goal. Thank you

Gretty K. Villena, Ph.D President, ICBi 2018 Lima, Peru

Rev. peru. biol. 27(1): 013 - 025 (March 2020) 013 Villena et al.

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