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schedule at a glance Andrology Lab Workshop 7:00 a.m. -6:00 p.m. Registration "Sperm Motility: A Hands-On Workshop" Location: Regency Main Desk Saturday, April 8, 2006 8:00 a.m. -9:00 a.m. AUA LECTURE Regulation of Prostate Development Postgraduate Course and Morphogenesis: "Issues in Male Sexual Health: From Benchwork to Bedside" Relationship to Prostate Carcinoma Saturday, April 8, 2006 Gail S. Prins, PhD University of Illinois at Chicago (Introducedby ArthurL. Burnett, MD) ASA 31sT ANNUAL MEETING Supported in part by an unrestricted "Contemporary Dimensions of educational grant from the American Urological Association Education and Male Reproductive Physiology and Health" Research Inc. Saturday, April 8 -Tuesday, April 11, 2006 9:00 a.m. -9:15 a.m. Distinguished Service Award *Location: Regency Ballroom CD, Gold Level, West To wer (unless otherwise noted) 9:15 a.m. -10:45 a.m. SY MPOSIUMI- SEXCH ROMOSOMES ANDS PERMATOGENESIS FRIDAY, APRIL 7, 2006 Co-chairs: Robert D. Oates, MD and Kirk Lo, MD 2:00 p.m. - 6:00 p.m. Registration The Cost of Palindromes in the Location: Regency Main Desk Human Y Chromosome Julian Lange, Graduate Student 4:00 p.m. -11 :00 p.m. Executive Council Meeting Whitehead Institute fo r Biomedical Location: To ronto Research SATURDAY, APRIL 8, 2006 Male Genes Out of X: Phenomena and Mechanisms 7:00 a.m. -7:00 p.m. Registration Manyuan Long, PhD Location: Regency Main Desk University of Chicago Why and How is the "Extra X" in 47, 4:00 p.m. -9:30 p.m. Exhibit Hall Open Location: Regency Foyer XXY Males So Harmful Ronald Swerdloff, MD Harbor-UCLA Medical Center 6:00 p.m. -6:10 p.m. Welcome and Opening Remarks President: Sally Perreault Darney, PhD 10:45 a.m. -12:30 p.m. Poster Session I US EnvironmentalProtection Agency Location: Regency AB Supported in part by an unrestricted Local Arrangements Chairs: educational grant from Mentor, Corp. Dale Buchanan Hales, PhD 12:30 p.m. -2:00 p.m. Lunch (on your own) University of Illinois at Chicago Susan M. Ta rchala, BS, TS 12:30 p.m. -2:00 p.m. Women in Andrology Luncheon and Rush Medical Center Discussion (not included in registration fe e; Program Chair: RobertD. Oates, MD tickets required) Boston University School of Medicine Location: Toronto 6:10 p.m. -6:30 p.m. Distinguished Andrologist Award 2:00 p.m. -3:30 p.m. Concurrent Oral Sessions I and II: Basic Biology of Sperm Function Moderators: Te rry Tu rner, PhD and 6:30 p.m. -7:30 p.m. ASA KEY NOTE LECTU RE T. Prabhakara Reddi, PhD The Future of Assisted Reproductive Location: Regency CD Technologies: Directions from Primates? Gerald Schatten, PhD A Potpourri of Intriguing Topics University of Pittsburgh School of Moderators: Janice Bailey, PhD and Medicine Alan B. Diekman, PhD (Introducedby Sally PerreaultDamey, PhD) Location: Acapulco Supported in part by an unrestricted educational grant from Serano, Inc. 3:30 p.m. -4:00 p.m. Refreshment Break Location: Regency Foyer 7:30 p.m. - 9:30 p.m. Welcome Reception Location: Plaza Ballroom, Green Level, 4:00 p.m. -4:45 p.m. LECTURE East Tower The Scientific Foundation for PDE5 Inhibitor Use in the Preservation of SUNDAY, APRIL 9, 2006 Erectile Function for the Prostate Cancer Patient 7:00 a.m. -8:00 a.m. Past President's Breakfast John P. Mulhall, MD Location: Hong Kong New Yo rk Presbyterian Hospital (Introduced by Wayne J.G. Hellstrom, MD) 7:00 a.m. -4:00 p.m. Exhibit Hall Open Location: Regency Foyer Supported in part by an unrestricted educational grant from Pfizer *Locations subjects to change SC edule at a glance 4:45 p.m. -5:30 p.m. LECTURE 12:30 p.m. -2:00 p.m. Editorial Board Luncheon Preimplantation Genetics: The Location: Hong Kong Technology, The Medicine and the Bioethics 2:00 p.m. -3:30 p.m. SYMPOSIUM Ill-ENDOCRINE ISSUES IN Mark R. Hughes, MD, PhD MALE REPRODUCTIVE FA ILURE Genesis Genetics Institute Co-chairs: Paul S. Cooke, PhD and (Introduced by Kenneth P. Roberts, PhD) Jon Pryor, MD 6:30 p.m. -8:30 p.m. Trainee Forum and Mixer Idiopathic Hypogonadotropic (All Trainee Travel Awards will be Hypogonadism: distributed and celebrated at this An Update on Genetic Etiolog ies event) Stephanie B. Seminara, MD Location: Toronto Massachusetts General Hospital MONDAY, APRIL 10, 2006 Strategies for Stimulating Androgen 7:00 a.m. -4:30 p.m. Exhibit Hall Open Production in Aging Men and Men Location: Regency Foyer with Secondary Hypogonadism Alvin M. Matsumoto, MD 7:00 a.m. -6:00 p.m. Registration University of Washington School of Location: Regency Main Desk Medicine 8:00 a.m. -9:00 a.m. WOMEN IN ANPROLOGY LECTURE On Genes and Infertility: Environmental Anti-Androgens: Unbiased Discovery Strategies Altered Development and Function of MaryAnn Handel, PhD the Male Reproductive Tract Th e Jackson Laboratory Vickie S. Wilson, PhD (Introduced by Janice P. Evans, PhD) US Environmental ProtectionAgency Supported in part by an unrestricted Supported in part by an unrestricted educational grant from Schering Germany II educational grant from Solvay Ber/ex USA 3:30 p.m. -4:00 p.m. Refreshment Break 9:00 a.m. -9:15 a.m. Yo ung Andrologist Award Location: Regency Foyer 9:15 a.m. -10:45 a.m. SYMPOSIUMII - CONTRACEPTION - 4:00 p.m. -4:45 p.m. BEYONDABSTINENCE LECTURE Embryonic Germ Cells and Nuclear Co-chairs: Erwin Goldberg, MD and Reprogramming Patricia L. Morris, PhD Niels Geijsen, PhD Eppin: An Effective Ta rget for Male Massachusetts General Hospital Contraception (Introduced by Robert S. Viger, PhD) Michael G. O'Rand, PhD University of North Carolina at Chapel Hill 4:45 p.m. -5:30 p.m. LECTURE Steroidogenic Factor 1 in Gonadal Te stis Specific Gene Products: Development and Function Targets for Contraceptive Keith L. Parker, MD, PhD Developments University of Te xas Southwestern Erwin Goldberg, PhD Medical Center NorthwesternUniversity (I ntroduced by Te rry T. Turner, PhD) Identification and Development of Supported in part by an unrestricted educational grant from Quest Diagnostics Novel Targets for Male Contraception Daniel S. Johnston, PhD 5:30 p.m. ASA Business Meeting, Wyeth Research Outstanding Trainee Investigator and Supported in part by an unrestricted Trainee Merit Awa rds educational grant from Wyeth Research 10:45 a.m. -12:30 p.m. Poster Session II 7:00 p.m. -11 :DO p.m. Annual Banquet Location: Regency AB (not included in registration fe e; tickets required) Supported in part by an unrestricted educational grant from Mentor, Corp. Location: Th e Mid-America Club 12:30 p.m. -2:00 p.m. Lunch (on your own) TUESDAY, APRIL 11,2006 12:30 p.m. -2:00 p.m. Inaugural Mentoring Luncheon Sponsored by the Minority Affairs and 7:00 a.m. -8:00 a.m. 2007 Program Committee Meeting Trainee Affa irs Committees: Location: Atlanta Career Development Patricia A. Martin-Deleon, PhD 7:30 a.m. -11 :DO a.m. Registration University of Delaware Location: Regency Main Desk Barry T. Hinton, PhD University of Virginia Location: To ronto (not included in registration; tickets require d; limited seating available) 2 schedule at a lance 8:00 a.m. -9:30 a.m. SYMPOSIUM IV - NEW DEVELOPMENTS IN SEX DETERMINATION AND TESTIS DIFFERENTIATION Co-Chair: Ajay Nangia, MD and Mark Sigman, MD Sex Chromosomes and Sex Hormones at Odds in Creating Neural Sex Differences Geert J. De Vries, PhD University of Massachusetts Homeobox Genes and Male Reproduction Miles F. Wilkinson, PhD University of Te xas, MD Anderson Cancer Center Role of Vascular Endothelial Growth Factor in Testis Morphogenesis Andrea Cupp, PhD University of Nebraska 9:30 a.m. -9:45 a.m. Break Location: Regency Foyer 9:45 a.m. -10:45 a.m. INTERNATIONAL LECTU RE Molecular Mechanisms Regulating Sperm Function; From Proteomics to table of contents Peroxidation John Robert Aitken, ScD, FRSE University of Newcastle Schedule at a Glance (Introduced by Patricia S. Cuasnicu, MD) President's Welcome 4 Supported in part by an unrestricted educational grant from the ASA Education Past Presidents 4 Endowment Fund ASA Officers 5 10:45 a.m. -12:00 p.m. SY MPOSIUM V-VALUE OF BASIC SCIENCEFO R ADVANCING CLINICAL General Information 6 PRACTICE AND PUBLICHEAL TH Co-chairs: Robert Brannigan, MD and Events & Activities 8 Rex Hess, PhD Message from the Program Chair 9 Sertoli Cell Toxicants: Theory and Practice ASA Lectureship Award . 10 Kim Boekelheide, MD, PhD Brown University Distinguished Andrologist Award 11 Tracking Distal Control Elements of Distinguished Service Award 12 FSHR by Comparative Genomics and Transgenic Analysis Yo ung Andrologist Award 13 Leslie Lynn Heckert, PhD University of Kansas Medical Center Outstanding Trainee Investigator Award. 13 Thanks to Donors & Sponsors 14 Course Objectives & CME Credit Information 15 Schedule of Events 17 Poster Session I 22 Poster Session II . 26 Index of Abstract Authors . 30 Abstracts 34 3 president's welcome It is with great personal pleasure that I welcome you to the 31 •1 Annual Meeting of the American Society of Andrology in the exciting city of Chicago. We are in a huge city but also in an intimate and informal setting where we can enjoy sharing science and interacting with friends and colleagues. Since 1979, when I attended my first ASA meeting in New Orleans as a graduate student, I have consistently enjoyed the diverse ASA programs where the basic and clinical sciences join hands. Our 2006 meeting begins on Saturday, April 8, with two educational opportunities: The Postgraduate Course and the Andrology Laboratory Workshop.