Datasheet Version: 1.0.0 Revision date: 05 Nov 2020
Inhibitor of Growth Protein 3 (ING3) Antibody Catalogue No.:abx004471
Western blot analysis of extracts of various cell lines, using ING3 antibody (abx004471) at 1/1000 dilution.
Immunofluorescence analysis of A549 cells using ING3 antibody (abx004471). Blue: DAPI for nuclear staining.
ING3 Antibody is a Rabbit Polyclonal antibody against ING3. The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.
Target: ING3
Clonality: Polyclonal
Reactivity: Human, Mouse, Rat
Tested Applications:ForWB, IF/ICC Reference Only
Host: Rabbit
Recommended dilutions: WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation: Unconjugated
Immunogen: Recombinant protein of human ING3.
v1.0.0 Abbexa Ltd, Cambridge, UK · Phone: +44 1223 755950 · Fax: +44 1223 755951 1 Abbexa LLC, Houston, TX, USA · Phone: +1 832 327 7413 www.abbexa.com · Email: [email protected] Datasheet Version: 1.0.0 Revision date: 05 Nov 2020
Isotype: IgG
Form: Liquid
Purification: Affinity purified.
Storage: Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC: Q9NXR8 (UniProt, ExPASy)
Gene Symbol: ING3
GeneID: 54556
String: 9606.ENSP00000320566
Molecular Weight: Calculated MW: 11 kDa, 46 kDa Observed MW: 50 kDa
Buffer: PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration: > 1 mg/ml
Note: This product is for research use only.
For Reference Only
v1.0.0 Abbexa Ltd, Cambridge, UK · Phone: +44 1223 755950 · Fax: +44 1223 755951 2 Abbexa LLC, Houston, TX, USA · Phone: +1 832 327 7413 www.abbexa.com · Email: [email protected]