In the News July 31, 2014

From: MountSinaiNewsNow Subject: Mount Sinai In The News - July 31, 2014 Date: Thursday, July 31, 2014 11:48:08 AM

The New York Times – July 31 Bothered by a ‘Gummy Smile’ Gummy smiles occur for a variety of reasons, most commonly a short upper lip, excessive gum tissue or small teeth, all of which are genetic. “Botox goes directly into the lip tissue, so there’s almost no risk of digesting it,” said Peter Taub, MD, Professor of Surgery, Pediatrics, Medical Education, and Dentistry at the Icahn School of Medicine at Mount Sinai. -Dr. Peter Taub, Professor of Surgery, Pediatrics, Medical Education, Dentistry, Icahn School of Medicine at Mount Sinai Learn more: http://well.blogs.nytimes.com/2014/07/31/bothered-by-a-gummy-smile/?_php=true&_type=blogs&_r=0

New York Daily News – July 30 Why is there not yet a Cure for Ebola? In the age of modern medicine, scientists are feverishly working to find a cure for the deadly Ebola virus, which can kill up to 90 percent of those it infects. "When you're infected with a virus, your cells sense the presence of an infection and respond by making a variety of proteins designed to stop the virus from replicating," said Christopher F. Basler, PhD, Professor of Microbiology at the Icahn School of Medicine at Mount Sinai. -Dr. Christopher F. Basler, Professor, Microbiology, Icahn School of Medicine at Mount Sinai Learn more: http://www.nydailynews.com/life-style/health/cure-ebola-article-1.1885957

Samuel Waxman Cancer Research Foundation Collaborator News – July 2014 Our Scientists Discover How Mutated Enzymes Cause a Deadly Form of Liver Cancer The Samuel Waxman Cancer Research Foundation congratulates its collaborating liver cancer researcher Josep Maria Llovet, MD, Director of the Liver Cancer Program, Division of Medicine at the Icahn School of Medicine at Mount Sinai, whose benchmark findings on Intrahepatic cholangiocarcinoma were recently published in the leading science journal Nature. -Dr. Josep Maria Llovet, Director, Liver Cancer Program, Division of Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.waxmancancer.org/News-Resources/Collaborator-News/Liver-Cancer-Team-Nature-Article

CNN – July 31 Number of 9/11-Related Cancer Cases is Growing Cancer is plaguing a growing number of first responders and rescuers who worked at ground zero after the terrorist attack on the World Trade Center on September 11, 2001. There are at least 1,646 certified cancer cases that have been documented by Mount Sinai Selikoff Centers for Occupational Health. There are some additional 863 cancer cases among both fire and EMS personnel, according to FDNY, which keeps a separate database for its members. -The Mount Sinai Hospital Learn more: http://www.cnn.com/2014/07/30/health/911-cancer-increase/

NPR – July 29 Getting Hospice Care Shouldn't Have To Mean Giving Up – Michelle Andrews It's a painful dilemma for seriously ill Medicare patients: To receive the extra support, counseling and care provided by the program's hospice benefit, they have to agree to stop receiving curative treatment for their disease. "I think it's a recognition that this forced choice between palliative care and life-prolonging treatment is irrational," said Diane Meier, MD, Professor of Geriatrics and Palliative Medicine and Director of the Center to Advance Palliative Care at the Icahn School of Medicine at Mount Sinai. -Dr. Diane Meier, Professor, Geriatrics and Palliative Medicine, and Director, Center to Advance Palliative Care, Icahn School of Medicine at Mount Sinai Learn more: http://www.npr.org/blogs/health/2014/07/28/336120433/getting-hospice-care-shouldnt-have-to-mean-giving-up

Brooklyn Daily – July 30 Standing O is at it Again! – Joanna DelBuono GraceAnn-Lautato Weick, RN, has been named the Vice President of Patient Care Services and Chief Operating Officer at Mount Sinai Beth Israel Brooklyn. -GraceAnn-Lautato Weick, Vice President, Patient Care Services, Chief Operating Officer, Mount Sinai Beth Israel Brooklyn Learn more: http://www.brooklyndaily.com/stories/2014/31/all-standingo-main-2014-08-01-bd_2014_31.html

Med City News – July 30 Accelerator Opens an New York City Hub with $51 Million in Backing from Pfizer, J&J, Lilly to Build New Life Sciences Startups – Meghana Keshavan Seattle’s Accelerator Corp. is expanding into New York City with $51.1 million in capital – and plans to raise more – to scout out life sciences innovators and entrepreneurs to form new biotechs based in New York City. Thanks to Accelerator’s heavy focus on translational research, it will partner with a number of top-notch institutions including the Icahn School of Medicine at Mount Sinai. -Icahn School of Medicine at Mount Sinai Learn more: http://medcitynews.com/2014/07/accelerator-opens-nyc-hub-51-million-backing-pfizer-jj-lilly-build-new-life-sciences- startups/

National Institutes of Health – July 29 Autism Architecture: Unrolling the Genetic Blueprint – Francis Collins In a recent study, the Population-Based Autism Genetics and Environment Study (PAGES) team, led by Joseph D. Buxbaum, MD, Director of the Seaver Autism Center for Research and Treatment and Professor of Psychiatry, Neuroscience and Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai, tapped into the powerful research resource provided by Sweden’s universal health registry. This analysis found that people with strictly defined autism tend to share more of certain genetic variants than people without the disorder. -Dr. Joseph D. Buxbaum, Director of the Seaver Autism Center for Research and Treatment and Professor of Psychiatry, Neuroscience and Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai Learn more: http://directorsblog.nih.gov/2014/07/29/autism-architecture-unrolling-the-genetic-blueprint/

Everyday Health – July 24 Study Links Shift Work to Risk for Type 2 Diabetes Those whose shifts moved around through different periods of the day were especially likely to develop type 2 diabetes than those who worked normal office hours. "Growth hormone, known to elevate blood glucose when present in excess, peaks at 1 a.m.," said Gerald Bernstein, MD, Director of the Diabetes Management Program at Friedman Diabetes Institute at Mount Sinai Beth Israel. "Shift work also often makes it more difficult to schedule regular meals and exercise." -Dr. Gerald Bernstein, Director, Diabetes Management Program, Friedman Diabetes Institute, Mount Sinai Beth Israel Learn more: http://www.everydayhealth.com/news/study-links-shift-work-to-risk-for-type-2-diabetes/

Healthline News – July 30 Ancient Mummies Prove Heart Disease Is as Old as We Are – Nina Lincoff Researchers have found evidence of atherosclerosis in a number of ancient mummies from around the world. Atherosclerosis is hardening of the arteries that lead to the heart caused by a buildup of plaque. “When we dig deeper into the lifestyle of these ancient people, we find that they were exposed to the same risk factors as we are today,” said Jagat Narula, MD, PhD, Associate Dean for Global Affairs, and Professor of Medicine and Cardiology at the Icahn School of Medicine at Mount Sinai. -Dr. Jagat Narula, Associate Dean for Global Affairs, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai Learn more: http://www.healthline.com/health-news/ancient-mummies-reveal-heart-disease-clues-073014

Men’s Journal – July 2014 Statin-Free and Still Ticking: The New Guide to Heart Health In the past few years, three major research reviews have arrived at the same conclusion: Statins provide real benefits to those who already have heart disease, but for those whose only risk factor is high LDL, not so much. David H. Newman, MD, Director of Clinical Research in the Department of Emergency Medicine at Icahn School of Medicine at Mount Sinai, has crunched the numbers for 25,000 to 30,000 people with no known heart disease who have been on statins for five years. The drugs saved no lives, but they did help prevent nonfatal heart attacks in 1.6 percent of this group. -Dr. David H. Newman, Director of Clinical Research in the Department of Emergency Medicine, Associate Professor of Emergency Medicine, at Icahn School of Medicine at Mount Sinai Learn more: http://www.mensjournal.com/health-fitness/health/statin-free-and-still-ticking-the-new-guide-to-heart-health-20140730

Senior Journal – July 30 Medicare Experiment Could Signal Sea Change for Hospice Care – Michelle Andrews There’s a lot of confusion about how hospice care differs from palliative care. Maybe we should start by clearing up what those terms mean. “The short, quick elevator answer is that all hospice care is palliative care -- but not all palliative care is hospice. Palliative care is a team-based type of care focused on maximizing the quality of life for people and their caregivers at any stage of illness,” said Diane Meier, MD, Professor of Geriatrics and Palliative Medicine and Director of the Center to Advance Palliative Care at the Icahn School of Medicine at Mount Sinai. -Dr. Diane Meier, Professor, Geriatrics and Palliative Medicine, and Director, Center to Advance Palliative Care, Icahn School of Medicine at Mount Sinai Learn more: http://www.seniorjournal.com/NEWS/Eldercare/2014/20140730_Medicare_Experiment_Could_Signal_Sea_Change_for_Hospice_Care.htm

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: MountSinaiNewsNow Subject: Mount Sinai In The News - July 30, 2014 Date: Wednesday, July 30, 2014 10:56:00 AM

In the News July 30, 2014

USA Today – July 30 New Study Identifies Why Some Deal With Stress Better – Rachel Chason A new study reveals why some people handle stress better than others. Eric Nestler, MD, Profess and System Chair of Neuroscience, Director of the Friedman Brain Institute, Professor of Pharmacology, Systems Therapeutics and Psychiatry at Icahn School of Medicine at Mount Sinai, said Dzirasa's paper is the first to look at how different areas of the brain interact when exposed to stressful situations. "It provides insight into the kinds of changes we would like to institute to either treat depression, or make people resilient so they wouldn't get depressed in the first place," Nestler said. - Dr. Eric Nestler, Professor and System Chair of Neuroscience, Director of the Friedman Brain Institute, Professor of Pharmacology, Systems Therapeutics and Psychiatry at Icahn School of Medicine at Mount Sinai Learn More: http://www.usatoday.com/story/news/nation/2014/07/29/study-underlying-cause- stress/13321593/

ABCNews.com – July 30 This Week on “NY Med” Surgeons at Mount Sinai’s Roosevelt Hospital Must Operate on a Two- Year-Old Girl…. – Nicole Enberg This week, at Mount Sinai Roosevelt Hospital, ER resident Amy Caggiula can diagnose anything that walks in the door, whether she’s saving a woman in cardiac arrest or figuring out how to cut a cheap ring off a young lady’s badly mangled finger. Also at Roosevelt, Alejandro Berenstein is a world leader in his field and works with pediatric neurosurgeon Saadi Ghatan to help save the life of the two-year- old daughter of a coast guard officer to prevent a catastrophic cerebral event. Also featured is resident Craig Forleiter of Mount Sinai Roosevelt. -Dr. Alejandro Berenstein, Director, Hyman Newman Institute for Neurology and Neurosurgery, Mount Sinai Roosevelt -Dr. Saadi Ghatan, Director of Pediatric Neurosurgery, Mount Sinai Health System -Dr. Amy Caggiula, Emergency Room Resident, Mount Sinai Roosevelt -Dr. Craig Forleiter, Resident, Mount Sinai Roosevelt Learn More: http://abcnews.go.com/blogs/headlines/2014/07/this-week-on-ny-med-surgeons-at-mount- sinais-roosevelt-hospital-must-operate-on-a-two-year-old-girl-who-could-suffer-a-catastrophic- cerebral-event-at-any-minute-if-they-are-unable-to-alter-the/

Everyday Health – July 30 FDA Approves Real-Life ‘Robocop’ Device – Dr. Sanjay Gupta Errol Samuels’ life changed on a spring night in 2012. He was at an off-campus college party and a patio roof collapsed on his back, paralyzing him from the waist down. We were with him in New York’s Central Park when, for the first time since the accident, he was preparing to take a walk in the park. The key is the computer, which allows the motors to work in synch. Walking is a series of controlled falls, explains Allan Kozlowski, PhD, Samuels' physical therapist and Assistant Professor of Rehabilitation Medicine at Icahn School of Medicine. - Dr. Allan Kozlowski, Assistant Professor of Rehabilitation Medicine at Icahn School of Medicine Learn more: http://www.everydayhealth.com/news/fda-approves-real-life-robocop-device/

Everyday Health – July 30 5 Surprising Uses for Aspirin – Aleksandra Mencel The benefits of aspirin far exceed temporary relief from fever, aches, and pains. Most people know that it can protect you from a heart attack or stroke, if taken properly. Research suggests that it can reduce the risk of some cancers and Alzheimer’s disease. But aspirin has many other potential health, beauty, and personal benefits. Discover some of the amazing things that bottle in your medicine cabinet can do for you. It “helps remove excess oil and exfoliate dead cells on the skin's surface,” says Joshua Zeichner, MD, Director of Cosmetic and Clinical Research in Dermatology, Assistant Professor of Dermatology. - Dr. Joshua Zeichner, Director of Cosmetic Research, Assistant Professor of Dermatology at Icahn School of Medicine Learn More: http://www.everydayhealth.com/news/surprising-uses-for-aspirin/

ABC News – July 30 7 Odd Reasons You Bruise Easily – Nina Elias You don't remember bumping into anything. Yet somehow, you have a shin full of bruises and a whole lot of questions. There are plenty of reasons for easy bruising, the discoloration caused by a trauma that ruptured blood vessels just under the skin. Check out the surprising explanations behind your sore spots and learn which ones are harmless and which ones need attention. "This is incredibly common in the 60+ population," says Gary Goldenberg, MD, Medical Director of Dermatology Faculty Practice, Assistant Professor of Dermatology and Pathology at Icahn School of Medicine. "It takes a lot less trauma to create a bruise than it ever did before in your life." - Dr. Gary Goldenberg, Medical Director of Dermatology Faculty Practice, Assistant Professor of Dermatology and Pathology at Icahn School of Medicine Learn more: https://abcnews.go.com/Health/Wellness/odd-reasons-bruise-easily/story?id=24760983

Yahoo! News – July 30 What Are Your Nails Trying to Tell you? – Annie Tomlin They say that eyes are the window to the soul, but as it turns out, nails may give us a glimpse of our overall health. “Fingernails should be a healthy, pinkish color,” says Jeannette Graf, MD, a Clinical and Research Dermatologist and Assistant Clinical Professor of Dermatology at Icahn School of Medicine at Mount Sinai. - Dr. Jeannette Graf, Assistant Clinical Professor of Dermatology at Icahn School of Medicine at Mount Sinai. Learn More: https://www.yahoo.com/beauty/what-are-your-nails-trying-to-tell-you-93222453184.html

Bleacher Report – July 30 Best-Case, Worst-Case Scenarios for David Wilson Following ‘Neck Burner’ – Davie Siebert Earlier this year, New York Giants running back David Wilson underwent spinal fusion surgery to repair a herniated disc in his neck. Andrew Hecht, MD, Co-Chief of Spine Surgery, Director of the Spine Center, Associate Professor of Orthopedics and Neurosurgery at Icahn School of Medicine —recently told The Austin Chronicle's Alex Dunlap that approximately half of NFL players will suffer a stinger at some point in their careers. - Dr. Andrew Hecht, Co-Chief of Spine Surgery, Director of the Spine Center, Associate Professor of Orthopedics and Neurosurgery at Icahn School of Medicine Learn more: http://bleacherreport.com/articles/2145641-best-case-worst-case-injury-scenarios-for-david- wilson-following-neck-burner

Prevention – July 30

The Supplements That Could Slash Your Risk of Sun Damage – Caroline Praderio When it’s time to protect our skin from the sun, we usually work from the outside in: diligently applying (and reapplying) sunscreen, donning our cover-ups, and creating our own shady oasis beneath wide-brimmed hats. “These are small studies that help reinforce what we commonly advise our patients: Oral antioxidants help minimize UV damage to the skin,” says Joshua Zeichner, MD, Director of Cosmetic Research, Assistant Professor of Dermatology at Icahn School of Medicine. - Dr. Joshua Zeichner, Director of Cosmetic Research, Assistant Professor of Dermatology at Icahn School of Medicine Learn More: http://www.prevention.com/beauty/beauty/natural-supplements-could-slow-aging-and- reduce-skin-cancer-risk

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: MountSinaiNewsNow Subject: Mount Sinai In The News - July 29, 2014 Date: Tuesday, July 29, 2014 1:38:11 PM

In the News July 29, 2014

Kaiser Health News – July 29 Medicare Experiment Could Signal Sea Change for Hospice – Michelle Andrews Diane Meier, [MD], is the director of the Center to Advance Palliative Care, a national organization that aims to increase the number of palliative care programs in hospitals and elsewhere for patients with serious illnesses. Meier is also a professor of geriatrics and palliative medicine at the Icahn School of Medicine at Mount Sinai Hospital. We spoke about a recently launched pilot program under the health law that allows hospice patients participating in the pilot to continue to receive life-prolonging treatment. - Dr. Diane Meier, Professor of Geriatrics, Medicine, and Palliative Medicine at the Icahn School of Medicine Learn More: http://www.kaiserhealthnews.org/Stories/2014/July/29/Medicare-Experiment-Could-Signal-Sea- Change-For-Hospice.aspx

Web MD – July 29 Will 3-D Printing Revolutionize Medicine? – Sonya Collins Imagine an ink jet printer that, rather than spraying out ink in the shape of letters, sprays out a plastic or metal gel or powder in the shape of a tooth, finger, or a hip joint. A typical printer receives a document to print, while 3-D printers take their commands from an MRI or a CT scan of a body part. Also known as “additive manufacturing,” 3-D printing produces an object, layer by layer, from the ground up. “The first printed windpipe may not be too far off either,” says Faiz Bhora, MD, Co-Director of Mount Sinai Hospital’s Airway Center, Associate Profess or Cardiothoracic Surgery at Icahn School of Medicine. Bhora and his colleagues are building windpipes both with plastic and gel bases in hopes of helping patients born with defects or tumors that block their airways. - Dr. Faiz Bhora, Co-Director of Mount Sinai Hospital’s Airway Center, Associate Profess or Cardiothoracic Surgery at Icahn School of Medicine. Learn More: http://www.webmd.com/news/breaking-news/20140723/3d-printing?page=4

Medpage Today – July 29 Do Decision Aids Help Patients Make Difficult Choices? – Shara Yurkiewicz Decision aids designed to help patients make general healthcare choices, such as selecting a treatment location, provide some help, but condition-specific aids may provide the most useful information for patients and families. "It gives us a good survey of the landscape," said Amy Kelley, MD, Assistant Professor of Geriatrics and Palliative Medicine at Icahn School of Medicine at Mount Sinai Hospital. - Dr. Amy Kelley, Assistant Professor of Geriatrics and Palliative Medicine at Icahn School of Medicine at Mount Sinai Hospital Learn More: http://www.medpagetoday.com/PracticeManagement/Medicolegal/46974

Allure – July 29 What You Need to Know About Allergic Reactions to Hair Dye – Katie Jenna Rosenstein Last week, NCIS star Pauley Perrette was rushed to the hospital because of a severe reaction to hair dye. Fortunately, she was fine—she even documented her hospital visit on Twitter (and posted a pretty gruesome picture), urging her half a million followers to learn about the warning signs of a reaction to dye. While reactions like Perrette's are rare (about one in 250,000 people are allergic), they can be really serious. Here’s what you need to know. "Types of reactions are variable and range from redness and itching to severe swelling," says Joshua Zeichner, MD, Assistant Professor of Dermatology and the Director of Cosmetic and Clinical Research at Mount Sinai Hospital. - Dr. Joshua Zeichner, Assistant Professor of Dermatology and the Director of Cosmetic and Clinical Research Learn more: http://www.allure.com/beauty-trends/blogs/daily-beauty-reporter/2014/07/what-you-need- to-know-about-hair-dye-allergies.html

Food Poisoning Bulletin – July 29 Groups Urge Congress to Reject Enlist Duo Herbicide – Linda Larsen Consumer groups, scientists, and doctors are urging congress to pressure the Obama administration to reject an application for “Enlist Duo ™ which is a new toxic herbicide made of 2,4-D and glyphosate. Philip Landrigan, MD, Dean for Global Health, Professor and System Chair of Preventative Medicine, Professor of Pediatrics at Icahn School of Medicine at Mount Sinai Hospital said, “exposures to herbicides in early life can lead to disease in childhood or disease later on in adult life or even old age. Herbicide chemicals can also cross from mother to child during pregnancy and prenatal exposures that occur during the nine months of pregnant are especially dangerous.” - Dr. Philip Landrigan, Dean for Global Health, Professor and System Chair of Preventative Medicine, Professor of Pediatrics at Icahn School of Medicine at Mount Sinai Hospital Learn more: http://foodpoisoningbulletin.com/2014/groups-urge-congress-to-reject-enlist-duo- herbicide/

Punch – July 29 Why are monogamous women who are negative for HPV still given Pap smears? The annual Pap smear has been a cornerstone of women’s health for at least 60 years, and is credited with preventing millions of deaths from cervical cancer. “HPV never leaves your body,” said Laura Corio, MD, Assistant Clinical Professor of Obstetrics, Gynecology and Reproductive Science at Icahn School of Medicine at Mount Sinai Hospital. - Dr. Laura Corio, Assistant Clinical Professor of Obstetrics, Gynecology and Reproductive Science at Icahn School of Medicine at Mount Sinai Hospital. Learn more: http://www.punchng.com/health/science-world/health-and-fitness-news-131/

The Verge – July 29

Fears Can Be Inherited Through Smell – Arielle Duhaime-Ross According to a new study, published today in Proceedings of the National Academy of Sciences, the mechanism [for fear] might be scent — at least when the fear occurs in mice. "Those of us who have studied populations such as adult children of Holocaust survivors have seen evidence of, and have attempted to describe, this kind of transmission in the clinical arena," said Rachel Yehuda, PhD, Professor of Psychiatry and Neuroscience, is the Director of the Traumatic Stress Studies Division at Mount Sinai Hospital. - Dr. Rachel Yehuda, Professor of Psychiatry and Neuroscience, is the Director of the Traumatic Stress Studies Division at Mount Sinai Hospital Learn More: http://www.theverge.com/2014/7/28/5944797/fears-can-be-inherited-through-smell

Fox News – July 29 How to Get Rid of Stretch Marks (At Least Temporarily) – Stephanie Nolasco It’s been reported that 90 percent of women will get stretch marks — those thin, ropey white lines on your stomach, thighs or breasts — over their lifetimes. “Women can try using a self-tanner to camouflage the marks and even out their skin tone,” says Stafford Broumand, MD, Associate Clinical Professor of Surgery at the Icahn School of Medicine at Mount Sinai. - Dr. Stafford Broumand, MD, Associate Clinical Professor of Surgery at the Icahn School of Medicine at Mount Sinai Learn More: http://magazine.foxnews.com/style-beauty/how-get-rid-stretch-marks-at-least-temporarily

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: MountSinaiNewsNow Subject: Mount Sinai In The News - July 28, 2014 Date: Monday, July 28, 2014 2:39:25 PM

In the News July 28, 2014

Daily Mail – July 28 Cancer Cases Double Among 9/11 World Trade Center Rescuers in Just One Year – Pedro Oliveira Jr. The number of first responders suffering from cancer after inhaling 9/11 fumes has more than doubled since last year, according to a new report. Some 1,655 cops, city workers, volunteers and locals exposed to toxins from the collapse of the World Trade Center have been diagnosed with the deadly disease, according to Mount Sinai Hospital's World Trade Center Health Program, which tracks the health of 37,000 first responders. - The Mount Sinai Hospital Learn more: http://www.dailymail.co.uk/news/article-2707388/9-11-Legacy-Cancer-cases-DOUBLE- World-Trade-Center-rescuers.html?ITO=1490&ns_mchannel=rss&ns_campaign=1490 Additional Coverage: The Telegraph http://www.telegraph.co.uk/news/worldnews/northamerica/usa/10994227/911-death-toll-rises-as-cancer- cases-soar-among-emergency-workers.html TVZN http://tvnz.co.nz/world-news/over-2-500-ground-zero-workers-diagnosed-cancer-6039198 News Max http://www.newsmax.com/Newsfront/911-workers-cancers-growing/2014/07/27/id/585157/ International Business Times http://www.ibtimes.co.uk/cancer-hits-more-2500-ground-zero-workers-1458646

U.S. Department of Veterans Affairs – July 28 What Goes Awry in the Suicidal Brain? Studies Zero in on Faulty Protein Some researchers sift through databases to find clues on why people kill themselves. Are certain diagnoses the main culprits? How about bad childhood experiences? "Suicide is a complex phenomenon," says Stella Dracheva, PhD, Associate Professor of Psychiatry at Icahn School of Medicine at Mount Sinai. "Only by using a very sophisticated combination approach were we able to find associations between genetics, epigenetics, gene editing, and gene expression. We've been able to find some very good leads." - Dr. Stella Dracheva, Associate Professor of Psychiatry at Icahn School of Medicine at Mount Sinai Learn more: http://www.research.va.gov/currents/summer2014/summer2014-11.cfm

Statesman Journal – July 28

Losing Weight May Ease Hot Flashes – Kristen Fischer Slimming down may help ease the hot flashes that often accompany menopause, new research suggests. "Fat appears to function as an insulator, and interferes with heat dissipation," explained Dr. Taraneh Shirazian, MD, Assistant Professor of Obstetrics, Gynecology and Reproductive Science at the Icahn School of Medicine at Mount Sinai. - Dr. Taraneh Shirazian, Assistant Professor of Obstetrics, Gynecology and Reproductive Science at the Icahn School of Medicine at Mount Sinai Learn More: http://www.statesmanjournal.com/story/life/wellness/2014/07/27/losing-weight-may-ease- hot-flashes/13223731/

Financial Times – July 28 Hepatitis C Researchers Battle to ‘Nuke’ the Competition – Andrew Ward The answers lie in Idenix’s portfolio of experimental treatmens for hepatitis C, widening Merck’s arsenal in the battle for supremacy over one of the hottest areas of drug development. “If you have to have Hepatitis C, now is the time to have it,” says Douglas Dieterich, MD, Professor of Medicine and Liver Diseases at the Icahn School of Medicine, Director of Continuing Medical Education in the Department of Medicine at Mount Sinai. - Dr. Douglas Dieterich, Professor of Medicine and Liver Diseases at the Icahn School of Medicine, Director of Continuing Medical Education in the Department of Medicine at Mount Sinai Learn more: http://www.ft.com/cms/s/0/000b5084-fc84-11e3-86dc-00144feab7de.html#axzz38ljfrDci

Healio Cardiology – July 28 AHA Grant Will Help Promote CV Health for High-Risk Children Four US institutions have been named an American Heart Association Strategically Focused Prevention Research Network Center and received a $15 million grant to promote CV health among high-risk children and their caregivers. “We hope to better understand how the intersection of a child’s behavior, environment and genetics lead to heart disease, which will refine our future prevention techniques,” said Valentin Fuster, MD, PhD, Physician-in- chief at Mount Sinai Hospital and Chief of the Division of Cardiology, Professor of Medicine and Cardiology, Icahn School of Medicine at Mount Sinai. - Dr. Valentin Fuster, Physician-in-chief at Mount Sinai Hospital and Chief of the Division of Cardiology, Professor of Medicine and Cardiology, Icahn School of Medicine at Mount Sinai. Learn more: http://www.healio.com/cardiology/pediatric-cardiology/news/online/%7Bdcb0047f-97dc- 4bd7-bc77-33fc809c1761%7D/aha-grant-will-help-promote-cv-health-for-high-risk-children

New York Daily News – July 28 Dr. Kelly Cassano on Fighting High Blood Pressure – Katie Charles The Mount Sinai Medical Group doctor says that lifestyle modifications, like losing weight and exercising, can help correct hypertension. “Generally, we consider a patient to have hypertension when they’ve shown high blood pressure on average of a few readings on three separate visits,” says Kelly Cassano, DO, Senior Medical Director of West Park Medical Group. - Dr. Kelly Cassano, Senior Medical Director of West Park Medical Group Learn more: http://www.nydailynews.com/life-style/health/daily-checkup-sunday-july-27-high-blood- pressure-article-1.1878782

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: Younghans, Johanna Subject: Mount Sinai In The News - July 25, 2014 Date: Friday, July 25, 2014 2:49:01 PM

In the News July 25, 2014

Forbes – July 25

Stronger Genetic Basis For Schizophrenia, Landmark Study Finds – Robert Glatter Schizophrenia, now known to have a genetic basis, leads to a delusional state characterized by abnormal perceptions, including agitation, paranoia, as well as hearing voices, which can also lead to violent behavior. “Clozapine is the most distinct of currently approved drugs for schizophrenia,” said Kyle Lapidus, MD, Assistant Professor of Psychiatry and Neuroscience at the Icahn School of Medicine. -Dr. Kyle Lapidus, MD, Assistant Professor of Psychiatry and Neuroscience at the Icahn School of Medicine Learn More: http://www.forbes.com/sites/robertglatter/2014/07/25/stronger-genetic-basis-for- schizophrenia-landmark-study-finds/

Everyday Health – July 25 New Evidence for Protective Effects of Vitamin D on Your Heart – Paolo Boffetta, MD Although vitamin D is obtained from diet and dietary supplements, the main source of vitamin D is production in our skin under the influence of solar radiation. I recommend moderate sun exposure, in particular in the elderly. The amount of sun exposure depends on the type of skin (15-30 minutes are sufficient for a fair skinned person, while one or two hours are needed for dark skinned person) and on the latitude the person lives (more time is needed in Northern regions, in particular in winter). - Dr. Paolo Boffetta, Director of the Institute for Translational Epidemiology and Associate Director for Population Sciences of The Tisch Cancer Institute; Bluhdorn Professor of International Community Medicine; Director Institute for Translational Epidemiology; Professor Oncological Sciences, Medicine, Hematology and Medical Oncology, Preventive Medicine, The Mount Sinai Hospital Learn more: http://www.everydayhealth.com/columns/health-answers/protective-effects-of-vitamin-d- for-your-heart/

CBS News – July 25 Lawn Chemical Can Stay in Body for “Years, Even Decades” The pesticides you use on your lawn to get rid of weeds and insects are part of a $10 billion-a-year industry. But some doctors are becoming more concerned about your exposure to those chemicals. "I think the fact that they have been around for a long time engenders a false sense of security," said Philip J. Landrigan, MD, MSc, the Ethel H. Wise Professor of Preventive Medicine, Dean for Global Health; Professor and System Chair Preventive Medicine; Professor Pediatrics at the Icahn School of Medicine at Mount Sinai. - Dr. Philip J. Landrigan, MSc, the Ethel H. Wise Professor of Preventive Medicine, Dean for Global Health; Professor and System Chair Preventive Medicine; Professor Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: http://www.cbsnews.com/news/lawn-chemicals-can-stay-in-human-body-for-years-even- decades/

Scientific American – July 25 Heparin Does Not Reduce Pregnancy Complications, and May Create Some – Dina Maron For the past 20 years pregnant women with an increased risk of developing blood clots have often been prescribed a common blood thinner to prevent serious complications from the clots, including preeclampsia (high blood pressure in the mother), disruption of the placenta, low birth weight and loss of the fetus. “Based on our study and our synthesis of the literature, I think that now we should really put this medication back on the shelf and look at other [drugs],” said Keith Eddleman, MD, Director of Obstetrics and a senior member of the Division of Maternal-Fetal Medicine in the Department of OB/GYN and Reproductive Science, Professor of Obstetrics, Gynecology and Reproductive Science Genetics, and Genomic Sciences, Icahn School of Medicine at Mount Sinai. - Dr. Keith Eddleman, MD, Director of Obstetrics and a senior member of the Division of Maternal- Fetal Medicine in the Department of OB/GYN and Reproductive Science, Professor of Obstetrics, Gynecology and Reproductive Science Genetics, and Genomic Sciences, Icahn School of Medicine at Mount Sinai. Learn more: http://www.scientificamerican.com/article/heparin-does-not-reduce-pregnancy- complications-and-may-create-some/

News Nurse – July 25 Mount Sinai Celebrate Magnet Achievements Nurses at Mount Sinai Hospital facilities celebrated two Magnet recognition announcements on July 17. “Collaboration, caring, and excellence are personified by the Magnet model,” said Carol Porter, DNP, RN, FAAN, Edgar M. Cullman, Sr., Chair of the Department of Nursing, Chief Nursing Officer/ Senior Vice President, Associate Dean of Nursing Research and Education, Icahn School of Medicine at Mount Sinai. - Carol Porter, Edgar M. Cullman, Sr., Chair of the Department of Nursing, Chief Nursing Officer/ Senior Vice President, Associate Dean of Nursing Research and Education, Icahn School of Medicine at Mount Sinai. Learn more: http://news.nurse.com/article/20140721/NY02/140718007#.U9JK_4BdVt5

PBR – July 25 Neurotrope, Mount Sinai to develop Bryostatin-1 for NPC treatment Neurotrope Bioscience has entered into a license agreement with Icahn School of Medicine at Mount Sinai to use its information and data package for the development of Bryostatin-1 to treat Niemann-Pick Type C Disease (NPC). "The submission of our joint provisional patent application further supports our belief in the therapeutic potential of bryostatin as an effective therapy in Alzheimer's and other neurodegenerative diseases,” the joint statement noted. -Dr. Yiannis Ioannou Professor of Genetics and Genomic Sciences Icahn School of Medicine Learn More: http://drugdiscovery.pharmaceutical-business-review.com/news/neurotrope-mount-sinai- to-develop-bryostatin-1-for-npc-treatment-240714-4326482

Punch – July 25 Tattoo Therapy After Breast Cancer Little Vinnie’s Tattoos offers designs ranging from swordfish and skulls to intricate Japanese-style art. But women who have undergone treatment for breast cancer do not typically come for traditional ink. They flock here seeking one thing — a three-dimensional nipple tattoo by the owner, Vinnie Myers. Skin grafts can recreate the look of the original nipple, but the procedure isn’t popular because “most patients don’t want to have another surgery and another scar,” said Leo Keegan, MD, Assistant Clinical Professor of Surgery at the Icahn School of Medicine at Mount Sinai. - Dr. Leo Keegan, Assistant Clinical Professor of Surgery at the Icahn School of Medicine at Mount Sinai Learn more: http://www.punchng.com/health/science-world/health-and-fitness-news-129/

Time Warner Cable News / New York 1 – July 25 Optimizing Your Herbal Regime for Whole Health – Jill Urban Whether it’s brewed in tea or taken as a supplement, Chinese herbal medicine is becoming more mainstream. “In general, you have to have a purpose. Whether it’s to enhance your energy, to enhance your good immune system to not get sick very often or to increase your digestion system,” said Xiu Min Li, MD, Director of Integrative Medicine, Professor of Pediatrics Allergy and Immunology Icahn School of Medicine at Mount Sinai. - Dr. Xiu Min Li, Director of Integrative Medicine, Professor of Pediatrics Allergy and Immunology Icahn School of Medicine at Mount Sinai Learn More: http://www.ny1.com/content/212798/optimizing-your-herbal-regimen-for-whole-health/

ABC 7 – July 25 Survey: Use of HGH on the Rise in Teenagers – Dr. Sapna Parikh It’s a problem that’s commonly associated with pro sports, like baseball or cycling, but doping is becoming a bigger issue on amateur teams, too. “Now we have new reports, new data to show it’s real, so parents, guardians, teachers, coaches have to be more aware,” said Robert Gotlin, MD, Director of Sports Rehabilition at Mount Sinai Beth Israel, Associate Professor of Rehabilitation Medicine at Icahn School of Medicine. - Dr. Robert Gotlin, Director of Sports Rehabilition at Mount Sinai Beth Israel, Associate Professor of Rehabilitation Medicine at Icahn School of Medicine Learn More: http://7online.com/health/use-of-hgh-on-the-rise-in-teenagers/213326/ Additional coverage: http://www.myfoxny.com/story/26096370/survey-teenagers-ped-use-is-up

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

Johanna Younghans I Media Specialist I Press Office, The Mount Sinai Health System p: 212.241.5093 I c: 646.315.2181 I e: [email protected]

From: Younghans, Johanna Subject: Mount Sinai In The News - July 24, 2014 Date: Thursday, July 24, 2014 12:21:52 PM

In the News July 24, 2014

Becker's Hospital Review – July 24 100 Hospitals, Health Systems With Great Oncology Programs Mount Sinai Hospital, ranked nationally for cancer care by U.S. News & World Report for 2014-15, offers the most advanced treatments for patients with all types of cancer. The Tisch Cancer Institute was established at Mount Sinai Health System in 2007, and its Dubin Breast Center, which opened in 2011, offers cutting-edge breast health services. In 2013, Tisch's gastrointestinal medical oncologists received the Quality Oncology Practice Initiative certification by the American Society of Clinical Oncology. - The Mount Sinai Hospital -Tisch Cancer Institute -Dubin Breast Center http://www.beckershospitalreview.com/100-oncology-programs-to-know-2014/100-hospitals-and- health-systems-with-great-oncology-programs-2014.html

Bloomberg – July 24 Who Gets Saved? Hepatitis Cure at $84,000 Makes Doctors Choose – Simon Bennett and Robert Langreth Early this year, liver specialist Ken Flora and his colleagues sent letters to 1,300 patients announcing exciting news: powerful new drugs to cure the lethal hepatitis C virus were finally available. “The number of people at the brink of developing severe damage is at an all-time high, and that is what creates the urgency,” said Andrea Branch, PhD, Professor of Medicine and Liver Diseases, Associate Professor of Surgery, Icahn School of Medicine at Mount Sinai. - Dr. Andrea Branch, Professor of Medicine and Liver Diseases, Associate Professor of Surgery, Icahn School of Medicine at Mount Sinai Learn more: http://www.bloomberg.com/news/2014-07-23/doctors-dilemma-who-gets-costly-cure-for- deadly-virus.html Additional Coverage: Herald Net http://www.heraldnet.com/article/20140724/NEWS02/140729539/Costly-hepatitis-C-cure-is-dilemma- for-doctors

Nephrology News and Issues – July 24 Nobel Laureates to Deliver Lectures at Transplant Congress Transplant professionals from across the globe will gather in San Francisco beginning this weekend for the World Transplant Congress (WTC), where more than 700 speakers and presenters will showcase results from groundbreaking research and clinical trials focused on advancements in solid organ and tissue transplantation. Eric Schadt, PhD, the Jean C. and James W. Crystal Professor of Genomics at the Icahn School of Medicine at Mount Sinai, and Director of the Icahn Institute for Genomics and Multiscale Biology, will deliver his State-of-the-Art address on Monday, July 28, during the WTC meeting. - Dr. Eric Schadt, the Jean C. and James W. Crystal Professor of Genomics at the Icahn School of Medicine at Mount Sinai, and Director of the Icahn Institute for Genomics and Multiscale Biology Learn more: http://www.nephrologynews.com/articles/110344-nobel-laureates-to-deliver-lectures-at- transplant-congress

Daily Times – July 24 Fad Diets You Should Absolutely Never Try What is the biggest issue with extreme forms of veganism? Food prep – it’s totally impractical, said Christopher N Ochner, PhD, Director of Research Development and Administration at the Mount Sinai Adolescent Health Center, Assistant Professor Pediatrics, Adolescent Medicine, Psychiatry, Icahn School of Medicine at Mount Sinai. - Dr. Christopher N. Ochner, Director of Research Development and Administration at the Mount Sinai Adolescent Health Center, Assistant Professor Pediatrics, Adolescent Medicine, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.dailytimes.com.pk/entertainment/24-Jul-2014/fad-diets-you-should-absolutely- never-try Additional Coverage: Fox News http://www.foxnews.com/health/2014/07/24/7-fad-diets-shouldnt-try/

Detroit Free Press – July 24 New Drug to Prevent Alzheimer’s Disease Enters Trial – Jane Lerner A $140 million study by the National Institutes of Health and the pharmaceutical company Eli Lilly will test the medication, solanezumab, to see if it can prevent the ravages of Alzheimer’s, which include memory loss and decline in cognitive function. The trial is being conducted at the Icahn School of Medicine at Mount Sinai. -Icahn School of Medicine at Mount Sinai Learn more: http://www.freep.com/article/20140723/FEATURES08/307230084/Alzheimer-s-drug-trial- solanezumab

North Jersey – July 24 Millburn Township Residents on ‘Best Doctors in New York’ List Clifford Sales, MD, and Sabino Torre, MD, were listed as a best doctor for vascular surgery and a best doctor for interventional cardiology respectively on New York’s annual list of "Best Doctors in New York" for 2014. - Dr. Clifford Sales, Assistant Clincal Professor of Surgery, Icahn School of Medicine at Mount Sinai - Dr. Sabino Torre, Adjunct Assistant Professor of Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.northjersey.com/community-news/community-events-and- announcements/doctors-on-best-in-ny-list-1.1056443

Health Day – July 24 Acetaminophen May Not Help Against Back Pain, Study Contends Even though its use is often advised by doctors, the painkiller acetaminophen – best known as Tylenol – does not help treat lower back pain, according to a new Australian study. "While this is a fascinating study, it is only one study and shouldn't change clinical behavior," said Houman Danesh, MD, Director of Integrative Pain Management and Assistant Professor of Anesthesiology and Rehabilitation Medicine at the Icahn School of Medicine at Mount Sinai. -Dr. Houman Danesh, MD, Director of Integrative Pain Management and Assistant Professor of Anesthesiology and Rehabilitation Medicine at the Icahn School of Medicine at Mount Sinai. Learn More: http://consumer.healthday.com/bone-and-joint-information-4/pain-health-news- 520/acetaminophen-may-not-help-against-back-pain-study-contends-690055.html

Time Warner Cable News / New York 1 – July 24 Learning From the Art and Science of Chinese Medicine – Jill Urban From herbs to acupuncture, many forms of Chinese medicine are becoming mainstream in the Western world, but many people don't understand the philosophy or complex practice of Chinese medicine. "Traditional Chinese medicine sees a human body as a whole system, like a network," said Xiu Min Li, MD, Director of Integrative Medicine, Professor of Pediatrics Allergy and Immunology Icahn School of Medicine at Mount Sinai. "The idea is that you have a bio-psycho-type, like, you're made up in a certain way," said Houman Danesh MD, Director of Integrative Pain Management and Assistant Professor of Anesthesiology and Rehabilitation Medicine at the Icahn School of Medicine at Mount Sinai. -Dr. Houman Danesh, MD, Director of Integrative Pain Management and Assistant Professor of Anesthesiology and Rehabilitation Medicine, Icahn School of Medicine at Mount Sinai -Dr. Xiu Min Li, Director of Integrative Medicine, Professor of Pediatrics Allergy and Immunology, Icahn School of Medicine at Mount Sinai Learn More: http://brooklyn.ny1.com/content/lifestyles/healthy_living/212720/learning-from-the-art- and-science-of-chinese-medicine/

Brooklyn Daily – July 24 Standing O – Joanna DelBuono Jennifer Marti, MD, is an Assistant Professor of Surgery, Icahn School of Medicine at Mount Sinai, a board-certified surgeon specializing in endocrine and breast surgery, and a new staffer at Mount Sinai Beth Israel Brooklyn. -Dr. Jennifer Marti, Assistant Professor of Surgery, Icahn School of Medicine at Mount Sinai Learn more: http://www.brooklyndaily.com/stories/2014/30/all-standingo-main-2014-07- bd_2014_30.html

Health – July 23 Could Yogurt Help Lower Blood Pressure? A new study suggests that potential help in lowering high blood pressure might be as close as your refrigerator. "The degree of blood pressure-lowering was modest," said Merle Myerson, MD, Assistant Professor of Cardiology and Medicine at the Icahn school of Medicine at Mount Sinai. -Dr. Merle Myerson, Assistant Professor of Cardiology and Medicine at the Icahn school of Medicine at Mount Sinai Learn More: http://news.health.com/2014/07/22/could-probiotics-help-tame-high-blood-pressure/

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

Johanna Younghans I Media Specialist I Press Office, The Mount Sinai Health System p: 212.241.5093 I c: 646.315.2181 I e: [email protected]

From: MountSinaiNewsNow Subject: Mount Sinai In The News - July 23, 2014 Date: Wednesday, July 23, 2014 12:20:16 PM

In the News July 23, 2014

Time – July 23 Here’s What Happens When You Get a Rape Kit Exam – Charlotte Alter Getting a rape kit collected is no picnic. The process can last up to four hours, and involves getting poked, prodded, swabbed and photographed in exactly the places a rape victim would have been violated in an attack. Monica Pombo of the Crime Victims Treatment Center at Mount Sinai St. Luke’s contributed to this story. -Monica Pombo, Crime Victims Treatment Center at Mount Sinai St. Luke’s Learn more: http://time.com/3001467/heres-what-happens-when-you-get-a-rape-kit-exam/

CBS News – July 23 Autism Risk Linked to Common Gene Variants – Robert Preidt Most of the genetic risk for autism appears to come from common gene variants rather than spontaneous gene mutations, according to a new study. "Genetic variation likely accounts for roughly 60 percent of the liability for autism, with common variants comprising the bulk of its genetic architecture," said Joseph D. Buxbaum, MD, Director of the Seaver Autism Center for Research and Treatment and Professor of Psychiatry, Neuroscience and Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai. -Dr. Joseph D. Buxbaum, Director of the Seaver Autism Center for Research and Treatment and Professor of Psychiatry, Neuroscience and Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai Learn more: http://www.cbsnews.com/news/autism-risk-linked-to-common-gene-variants/ Additional Coverage: Scientific American http://www.scientificamerican.com/article/common-mutations-account-for-bulk-of-autism-risk/ CNN http://thechart.blogs.cnn.com/2014/07/22/genetics-play-a-bigger-role-than-environmental-causes-for- autism/?iref=allsearch

Nature – July 23 Gene-Hunt Gain for Mental Health – Sara Reardon Researchers seeking to unpick the complex genetic basis of mental disorders such as schizophrenia have taken a huge step towards their goal. A paper published in Nature this week ties 108 genetic locations to schizophrenia — most for the first time. The encouraging results come on the same day as a US$650- million donation to expand research into psychiatric conditions. “It’s a stunning confirmation that there are many, many genetic factors” said Pamela Sklar, MD, PhD, Professor, Psychiatry, Neuroscience, Genetics and Genomic Sciences Icahn School of Medicine at Mount Sinai. “And because these variants are so rare, a larger sample size will be necessary to determine the truly important ones,” said Joseph D. Buxbaum, MD, Director of the Seaver Autism Center for Research and Treatment and Professor of Psychiatry, Neuroscience and Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai. -Dr. Joseph D. Buxbaum, Director of the Seaver Autism Center for Research and Treatment and Professor of Psychiatry, Neuroscience and Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai -Dr. Pamela Sklar, Professor, Psychiatry, Neuroscience, Genetics and Genomic Sciences Icahn School of Medicine at Mount Sinai Learn more: http://www.nature.com/news/gene-hunt-gain-for-mental-health-1.15602

Healio – July 23 ACG Updates Guidelines for Management of Benign Anorectal Disorders – Adam Leitenberger One major point of recent guidelines [for management of benign anorectal disorders] is really nicely outlined in the algorithm for evaluation and management of defecatory disorders (DD). It basically says to document DD with anorectal manometry plus balloon expulsion test (BET), and at that point if patients undergo biofeedback and show improvement you can just follow them clinically. -Dr. Gina Sam, Director, Mount Sinai Gastrointestinal Motility Center, Assistant Professor of Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.healio.com/gastroenterology/therapeutics- diagnostics/news/online/%7B04192188-d5da-404e-9aea-7d21f738469d%7D/acg-updates-guidelines-for- management-of-benign-anorectal-disorders?page=1&Filter

Brides – July 23 Say Goodbye to Sun Damage Before your Wedding – Amanda First Turns out, the retinol creams you use on your face work just as well on your chest. Every time you apply, make sure not to neglect your neck and décolleté. “Ever laid out on the beach, slathered with SPF, and still come home with a sunburn on your chest? You're not alone,” said Angela Lamb, MD, Assistant Professor of Dermatology at the Icahn School of Medicine at Mount Sinai. -Dr. Angela Lamb, Assistant Professor of Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://www.brides.com/blogs/aisle-say/2014/07/fix-sun-damage-on-chest-before- wedding.html

Refinery 29 – July 23 What Really Works to Treat Acne – Annie Tomlin Sometimes, when we’re glaring at an out-of-nowhere bump on our nose, we have to wonder whether anything will ever send acne packing for good. And, of the purported "cures" out there, which ones actually lead to the clear complexion we’ve always dreamed of — and which are just a bunch of hokum? “There are effective [antibiotics], especially oral antibiotics,” said Joshua Zeichner, MD, Associate Professor of Dermatology, Icahn School of Medicine at Mount Sinai. “The goal is to treat [with oral antibiotics] along with topicals and benzoyl peroxide, which helps minimize the development of resistance.” -Dr. Joshua Zeichner, Associate Professor of Dermatology, Icahn School of Medicine at Mount Sinai Learn More: http://www.refinery29.com/best-acne-treatment#slide-1

Medpage Today – July 23 FDA Issues Reformed Consent Guidance – Joyce Freiden The FDA recently issued an updated guidance document on obtaining informed consent for clinical trials, but little has changed that would affect enrollment, according to one expert. "It was never a requirement at all that people be informed what happened, so this is a big change and a very positive change," said Rosamond Rhodes, PhD, Director of Bioethics Education, Professor of Medical Education, Icahn School of Medicine at Mount Sinai. -Dr. Rosamond Rhodes, Director of Bioethics Education, Professor of Medical Education, Icahn School of Medicine at Mount Sinai Learn More: http://www.medpagetoday.com/PublicHealthPolicy/ClinicalTrials/46888

Pharmacy Choice – July 23 Novartis Announces NEJM Publication of Two Pivotal Phase III Secukinumab Studies Demonstrating Statistically Significant Skin Clearance in Psoriasis Novartis announces NEJM publication of two pivotal Phase III secukinumab studies demonstrating statistically significant skin clearance in psoriasis patients. "These data add to our growing understanding of psoriasis and the key role the IL-17 pathway plays in the pathophysiology of the disease," said Mark G. Lebwohl, MD, Sol Kest, Chair of the Department of Dermatology at the Icahn School of Medicine at Mount Sinai. -Dr. Mark G. Lebwohl, Sol Kest, Chair of the Department of Dermatology at the Icahn School of Medicine at Mount Sinai. Learn more: http://www.pharmacychoice.com/news/article.cfm?Article_ID=1233274

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: MountSinaiNewsNow Subject: Mount Sinai In The News - July 22, 2014 Date: Tuesday, July 22, 2014 1:52:41 PM

In the News July 22, 2014

The New York Times – July 22 Credibility Among Gay Men Gives Leverage to New York City’s New Chief of H.I.V. Prevention – Anemona Hartocollis At the height of a meningitis outbreak last year among gay and bisexual men in New York City, Demetre Daskalakis, Senior Faculty of Medicine and Infectious Diseases, Icahn School of Medicine at Mount Sinai, spent late nights and early mornings in the city’s sex clubs and bathhouses. There, he would strip off his leather jacket and, in his muscle T-shirt, talk the men around him into letting him inject them with meningitis vaccines. “Life with H.I.V. or risk of H.I.V. — my personal perspective is that that’s scary enough,” said Dr. Daskalakis. -Dr. Demetre Daskalakis, Senior Faculty of Medicine and Infectious Diseases, Icahn School of Medicine at Mount Sinai Learn more: http://www.nytimes.com/2014/07/22/nyregion/credibility-among-gay-men-gives-leverage-to-new-york-citys-new-chief- of-hiv-prevention.html?_r=0

Yahoo – July 22 IBS Breakthrough: Immune Cell's Role in Digestive Tract Could Lead to New Treatments – Mary-Ann Russon Researchers from several US universities have discovered a link between an immune system cell called a "macrophage" that helps to fight infections, and the contractions of the colon that push digested food through the digestive tract. The Mount Sinai Hospital attributed to the research. -The Mount Sinai Hospital Learn more: https://uk.news.yahoo.com/ibs-breakthrough-immune-cells-role-digestive-tract-could-140430992.html

Healio Cardiology Today – July 22 Myocardial Damage After TAVR Decreased LV Function After transcatheter aortic valve replacement, detection of late enhancement, a measure of myocardial injury, by cardiac MRI was common and associated with a significant decrease in left ventricular function at discharge, new data concluded. “After transcatheter aortic valve replacement, detection of late enhancement, a measure of myocardial injury, by cardiac MRI was common and associated with a significant decrease in left ventricular function at discharge, new data concluded,” said Geroge Dangas, MD, Professor of Cardiology, Medicine, Surgery, and Javier Sanz, MD, Associate Professor Cardiology, Medicine, Radiology at the Icahn School of Medicine at Mount Sinai. -Dr. Geroge Dangas, Professor of Cardiology, Medicine, Surgery, Icahn School of Medicine at Mount Sinai -Dr. Javier Sanz, Associate Professor Cardiology, Medicine, Radiology, Icahn School of Medicine at Mount Sinai Learn more: http://www.healio.com/cardiology/intervention/news/online/%7B86beb235-b34c-48a1-bda4- 2ad7a2430602%7D/myocardial-damage-after-tavr-decreased-lv-function

Medpage Today – July 21 HPS2-THRIVE: Game (Mostly) Over for Niacin – Crystal Phend Publication of the landmark HPS2-THRIVE trial findings affirmed no benefit and worrisome adverse events from adding extended- release niacin to statin therapy, but many physicians weren't ready to concede failure of the purported HDL mechanism. "The use of niacin has been limited for high-risk patients with high LDL cholesterol levels and/or high lipoprotein(a) levels who have not adequately responded to high-intensity statin therapy in the absence or combination with either ezetimibe or colesevelam [WelChol],” said Robert Rosenson, MD Professor of Medicine, Cardiology, Director of Cardiometabolic Disorders at The Mount Sinai Hospital. -Dr. Robert Rosenson, Professor of Medicine, Cardiology, Director of Cardiometabolic Disorders, The Mount Sinai Hospital Learn more: http://www.medpagetoday.com/Cardiology/Prevention/46834

Med City News – July 22 Who Made the Cut for New York Digital Health Accelerator? New York Digital Health Accelerator has picked seven health IT startups and growth-stage companies for its four month program. The hopes for the accelerator companies is that they are as effective in in surmounting healthcare challenges as they are in building jobs. Noom develops health and wellness apps around nutrition. Last year it secured a two-year NIH grant to study the effectiveness of an app to track binge eaters to gain insights into their behavior. The study is being led by Tom Hildebrandt, PhD, Associate Professor of Psychiatry at the Icahn School of Medicine at Mount Sinai. -Dr. Thomas B. Hildebrandt, Associate Professor Psychiatry Icahn School of Medicine at Mount Sinai Hospital Learn More: http://medcitynews.com/2014/07/made-cut-new-yorks-digital-health-accelerator/#ixzz38CaSpz1o

Fox News – July 22 A New and Yummy Supplement to Prenatal Vitamins – Lindsay Carlton When you’re pregnant or trying to conceive, prenatal vitamins can be your best friend – and sometimes your worst enemy. “Folic acid is really important, because studies have shown that taking enough folic acid can reduce a very important fetal malformation or birth defect called spina bifida or neural tube defect that can also affect the brain as well,” said Joanne Stone, MD, Professor of Obstetrics, Gynecology, Reproductive Science at Icahn School of Medicine at Mount Sinai. -Dr. Joanne Stone, Professor of Obstetrics, Gynecology, Reproductive Science at Icahn School of Medicine at Mount Sinai Learn more: http://www.foxnews.com/health/2014/07/21/new-and-yummy-supplement-to-prenatal-vitamins/

Medpage Today – July 22 Newman's Notes: Inside the Ondansetron Black Box – Elbert Chu Ondansetron (trade name Zofran) has been around for about two decades now and there's been a whole lot of talk recently about a black box warning that the FDA put on it. "Listen, if there is a black box warning and anything goes wrong, we're going to be held responsible for that," said David H. Newman, MD, Director of Clinical Research in the Department of Emergency Medicine at Icahn School of Medicine at Mount Sinai. -Dr. David H. Newman, Director of Clinical Research in the Department of Emergency Medicine, Associate Professor of Emergency Medicine, at Icahn School of Medicine at Mount Sinai Learn more: http://www.medpagetoday.com/EmergencyMedicine/EmergencyMedicine/46851

Women’s Health – July 22 Nine Eating Habits That Are Derailing Your Weight-Loss Efforts – Aleisha Fetters The occasional dietary splurge isn't what really thwarts most women's weight-loss efforts. It's the so-called "healthy" weight-loss strategies we use, convinced they'll help us cut calories, slim down, and get healthier—only to see our scales stay put. Just keep an eye out for these habits — and then nix them accordingly. "Gluten-free pasta made with whole grains — i.e., whole grain brown rice, quinoa, etc. — are absolutely fine alternatives to regular pasta," said Jaclyn London, RN, MS, CDN, Senior Clinical Dietitian at The Mount Sinai Hospital. -Jaclyn London, Senior Clinical Dietitian, The Mount Sinai Hospital Learn more: http://www.womenshealthmag.com/weight-loss/eating-habits-derailing-weight-loss

Women’s Health – July 22 Four Spice That Can Help You Lose Weight – Jenna Birch While research suggests that pretty much all herbs and spices are beneficial for dropping pounds (since the added flavor can help you feel more satisfied with low-cal foods), certain ones are particularly helpful to add to your pantry when you're on a mission to slim down. "The key is that all the ones we talk about for weight loss or maintenance have anti-inflammatory properties and a flavor profile that may help limit overall calorie intake," said Jaclyn London, RN, MS, CDN, Senior Clinical Dietitian at The Mount Sinai Hospital. -Jaclyn London, Senior Clinical Dietitian, The Mount Sinai Hospital Learn more: http://www.womenshealthmag.com/weight-loss/spices-that-help-lose-weight

Health Day – July 22 Could Probiotics Tame High Blood Pressure? A new study suggests that potential help in lowering high blood pressure might be as close as your refrigerator. "The degree of blood pressure-lowering was modest," said Merle Myerson, MD, Assistant Professor of Cardiology and Medicine at the Icahn school of Medicine at Mount Sinai. -Dr. Merle Myerson, Assistant Professor of Cardiology and Medicine at the Icahn school of Medicine at Mount Sinai. Learn more: http://consumer.healthday.com/cardiovascular-health-information-20/high-blood-pressure-health-news-358/could- probiotics-help-tame-high-blood-pressure-689840.html Additional Coverage: Philly.com: http://www.philly.com/philly/health/hearthealth/HealthDay689840_20140721_Could_Probiotics_Help_Tame_High_Blood_Pressure_.html Doctor’s Lounge: http://www.doctorslounge.com/index.php/news/hd/48288 Web MD: http://www.webmd.com/hypertension-high-blood-pressure/news/20140721/could-probiotics-help-tame-high-blood-pressure

Life Script – July 22 How to Handle Ulcerative Colitis Flare – Dana Gottesman If you have ulcerative colitis, you’re probably all too familiar with the disease’s cycle of remission and flares. “Keeping a dietary log is one of the most effective tools for pinpointing troublesome foods,” said Laura Manning, RD, CDN, a Clinical Dietitian in the division of Gastroenterology at The Mount Sinai Hospital. “To get relief, try stress-reduction practices, such as yoga. Or do a walking meditation in your local park. These help relieve symptoms by reducing stress hormones (such as cortisol), muscle tension and the perception of pain and discomfort in your body,” said Anne M. Fatone, PhD, a Psychologist at The Mount Sinai Hospital, and Assistant Clinical Professor at the Icahn School of Medicine at Mount Sinai. -Dr. Anne M. Fatone, PhD, Psychologist, The Mount Sinai Hospital, Assistant Clinical Professor, Icahn School of Medicine at Mount Sinai -Laura Manning, a Clinical Dietitian in the division of Gastroenterology, The Mount Sinai Hospital Learn more: http://www.lifescript.com/health/centers/ulcerative_colitis/articles/how_to_handle_an_ulcerative_colitis_flare.aspx

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: MountSinaiNewsNow Subject: Mount Sinai In The News - July 21, 2014 Date: Monday, July 21, 2014 12:16:44 PM

In the News July 21, 2014

HealthDay – July 21 Common Gene Variants Account for Most Genetic Risk for Autism A recent study has proved that 60 percent of the risk for developing autism is caused by genetics and a major portion of that risk is caused by inherited variant genes that are common in the population and present in individuals without the disorder. Joseph D. Buxbaum, MD, Director of the Seaver Autism Center for Research and Treatment and Professor of Psychiatry, Neuroscience and Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai, said that they have shown very clearly that inherited common variants comprise the bulk of the risk that sets up susceptibility to autism and while there are families that can be genetically loaded for autism risk, additional rare genetic factors are required to actually produce the disorder in a particular family member. -Dr. Josepsh Buxbaum, Professor Psychiatry, Neuroscience, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai. Learn more: http://consumer.healthday.com/cognitive-health-information-26/autism-news-51/gene- mutations-autism-nature-genetics-carnegie-mellon-nimh-releases-689927.html Additional Coverage: Science Codex: http://www.sciencecodex.com/common_gene_variants_account_for_most_genetic_risk_for_autism- 137863 News-Medical: http://www.news-medical.net/news/20140721/Study-Genetics-plays-major-role-in- development-of-autism.aspx ANI News: http://www.aninews.in/newsdetail9/story176546/-039-common-039-rare-genetic-factors- responsible-for-developing-autism-study.html CBS 19 (Texas): http://www.cbs19.tv/story/26067950/health-alert-hiv-rates-declining

WNBC-TV – July 19 Vitamin D Benefits – Chris Glorioso Dr. Paolo Boffetta, Director of the Institute for Translational Epidemiology and Associate Director for Population Sciences of the Tisch Cancer Institute, joins Chris Glorioso to talk about the health benefits of vitamin D. -Dr. Paolo Boffetta, Director, Institute of Translational Epidemiology, Professor, Oncological Sciences, Medicine, Hematology and Medical Oncology, Preventive Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.domain-b.com/technology/Health_Medicine/20140709_treatment.html

Medpage Today – July 21 Resuscitation in the ED: Beyond the ABCs – Reuben Strayer, MD Approaching a critically ill patient can be nerve-racking, and when your nerves are racked it can be hard to remember what to do. However, when you remember what to do, your nerves get less racked. So, I'm going to present a top-down approach to resuscitation that uses an expanded ABC's mnemonic to jog your memory and unrack your nerves. -Dr. Reuben Strayer, Assistant Clinical Professor of Emergency Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.medpagetoday.com/EmergencyMedicine/EmergencyMedicine/46846

Medpage Today – July 21 HPS2-THRIVE: Game (Mostly) Over for Niacin – Crystal Phend Publication of the landmark HPS2-THRIVE trial findings affirmed no benefit and worrisome adverse events from adding extended-release niacin to statin therapy, but many physicians weren't ready to concede failure of the purported HDL mechanism. "The use of niacin has been limited for high-risk patients with high LDL cholesterol levels and/or high lipoprotein(a) levels who have not adequately responded to high-intensity statin therapy in the absence or combination with either ezetimibe or colesevelam [WelChol],” said Robert Rosenson, MD Professor of Medicine, Cardiology, Director of Cardiometabolic Disorders at The Mount Sinai Hospital. -Dr. Robert Rosenson, Professor of Medicine, Cardiology, Director of Cardiometabolic Disorders, The Mount Sinai Hospital Learn more: http://www.medpagetoday.com/Cardiology/Prevention/46834

Haaretz – July 21 Tendency to PTSD Could Be Inherited, Scientists Say – Josie Glausiusz A recently-published study on children of Holocaust survivors, conducted by neuroscientist Rachel Yehuda, MD, Director of the Traumatic Stress Studies Division at the Icahn School of Medicine at Mount Sinai, indicates that predisposition may be transmitted via epigenetic means. "Epigenetic" refers to the control of genes – they are turned on and off by the binding of chemicals secreted by the body, which change with circumstance. -Dr. Rachel Yehuda, Director of the Traumatic Stress Studies Division, Professor of Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: http://www.haaretz.com/life/health-fitness/.premium-1.606334

Maclean’s – July 21 The Little Girl Who May Hold the Secret to Aging – Kate Lunau Brooke Greenberg, who lived near Baltimore with her family, resembled an infant when she was a preteen. The Greenbergs formed a new alliance with Eric Schadt, PhD, Director of the Icahn Institute for Genomics and Multiscale Biology at The Mount Sinai Hospital. When Greenberg’s father first told Dr. Schadt that his daughter, then 19, resembled a toddler, “I was a little skeptical,” said Dr. Schadt. “It seemed hard to believe.” His team has created a line of stem cells from Brooke’s skin, and are using them to grow liver cells, fat cells, neurons, and other building blocks of her body, to study the impact of each mutation, and how it may relate to aging and disease. -Dr. Eric Schadt, Director of the Icahn Institute for Genomics and Multiscale Biology, Professor and Systems Chair of Genetics and Genomic Studies Learn more: http://www.macleans.ca/society/health/the-little-girl-who-may-hold-the-secret-to-aging/

Fox News (from Women’s Health) – July 21 Woman Eats Dog Food for 30 Days to Prove it’s Healthier than Human Food – Brettan Hawkins Dorothy Hunter, owner of the Paw's Natural Pet Emporium chain, is eating only dog, cat, and bird food for a total of 30 days to promote ingredient awareness – with foods for both humans and animals. “Someone eating pet foods also runs the significant risk of contracting food borne illness from eating foods not intended for the human gut,” said Jaclyn London, RN, MS, CDN, Senior Clinical Dietitian at Mount Sinai Hospital. -Jaclyn London, RN, MS, CDN, Senior Clinical Dietitian at Mount Sinai Hospital Learn more: http://www.foxnews.com/health/2014/07/21/woman-eats-dog-food-for-30-days-to-prove- it-healthier-than-most-human-foods/

Gothamist – July 21 New York Women Under Medicaid Can Now Get IUDs Immediately After Giving Birth – Lauren Evans New York women insured by Medicaid will now have the option of receiving an intrauterine device or contraceptive implant immediately following childbirth, sparing them the additional step of booking an inconvenient follow-up appointment, Health Commissioner Dr. Mary Bassett announced yesterday. Laura MacIsaac, MD, Associate Professor of Obstetrics, Gynecology and Reproductive Science, who heads the Family Planning Division of Mount Sinai Beth Israel, said as a provider, she's been frustrated by the bureaucratic red tape that's come between her and her ability to provide her patients with the reproductive care they want. -Dr. Laura MacIsaac, Associate Professor Obstetrics, Gynecology and Reproductive Science, Family Planning Division Learn more: http://gothamist.com/2014/07/18/new_york_women_covered_by.php Additional Coverage NYC.gov: http://www.nyc.gov/html/doh/html/pr2014/pr021-14.shtml

New York Daily News – July 21 Daily Checkup: Sarcomas are Tumors of the Connective Tissues of the Body – Katie Charles July is sarcoma awareness month. Sarcoma is a tumor of the tissues that hold us together — bone, muscles, and other things that aren’t organs,” said Robert G. Maki, MD, PhD, Professor Pediatrics, Hematology, Oncology, Orthopaedics, Steven Ravitch Chair in Pediatric Hematology-Oncology. -Dr. Robert G. Maki, MD, PhD, Professor, Pediatrics, Hematology, Oncology, Orthopaedics, Steven Ravitch Chair in Pediatric Hematology-Oncology Learn more: http://www.nydailynews.com/life-style/health/daily-checkup-july-20-sarcomas-article- 1.1866225

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: MountSinaiNewsNow Subject: Mount Sinai In The News - July 18, 2014 Date: Friday, July 18, 2014 1:21:35 PM

In the News July 18, 2014

Crain’s Health Pulse – July 18 At A Glance: Who's News Mantu Gupta, MD, is now Chairman of Urology at Mount Sinai Roosevelt and Mount Sinai St. Luke's, and will lead the Endourology and Stone Diseases Program across The Mount Sinai Health System. He had been Associate Professor, Director of Endourology and Director of the Kidney Stone Center at Columbia University Medical Center. -Dr. Mantu Gupta, Director, Kidney Stone Center of Mount Sinai, Chair, Urology, Mount Sinai St. Luke's, Mount Sinai Roosevelt Learn more (Subscription required): http://www.crainsnewyork.com/article/20140718/PULSE/140719859/contract-deal- with-1199-and-ifh

Reuters – July 18 Healthy Living May Slow Early Dementia – Andrew Seaman A program that emphasizes healthy eating, brain and social engagement, physical activity and heart health may slow dementia among people at risk for Alzheimer’s disease, said a new preliminary report. "I think the evidence is that this delays onset for people who don’t have it,” said Sam Gandy, PhD, Professor of Neurology and Psychiatry, and Associate Director of the Mount Sinai Alzheimer’s Disease Research Center at the Icahn School of Medicine at Mount Sinai. -Dr. Sam Gandy, Professor of Neurology and Psychiatry, Associate Director, Mount Sinai Alzheimer’s Disease Research Center, Icahn School of Medicine at Mount Sinai Learn more: http://www.reuters.com/article/2014/07/17/us-alzheimers-prevention-trial-idUSKBN0FM2P820140717 Additional Coverage: WHTC: http://whtc.com/news/articles/2014/jul/17/healthy-living-may-slow-early-dementia-study/

ABC News – July 18 Seven Fad Diets You Shouldn’t Try Any weight-loss expert would agree that boosting your veggie and fruit intake while reducing the amount of junk you eat is a safe and effective way to lose weight, but this diet bans foods that have been cooked or processed in any way. “The biggest issue with this extreme form of veganism? Food prep — it's totally impractical,” said Christopher Ochner, PhD, Assistant Professor Pediatrics, Adolescent Medicine, Assistant Professor Psychiatry, at the Icahn School of Medicine at Mount Sinai. -Dr. Christopher Ochner, Assistant Professor Pediatrics, Adolescent Medicine, Assistant Professor Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://abcnews.go.com/Health/Wellness/fad-diets/story?id=24603959#1

Medpage Today – July 18 Acne App Takes Telemedicine to New Level – Parker Brown Using the PocketDerm app, patients send in pictures of their acne and receive a diagnosis from a licensed dermatologist. Prescriptions come through the mail. "I just think it's a very simplistic way to treat a medical condition, and they can't offer the broad scope of things. What if the patient needs laser treatment for it? What if there's a hormonal issue that's causing the problem?" said Cameron K. Rokhsar, MD, FAAD, FAACS, Assistant Clinical Professor Dermatology at The Mount Sinai Hospital. "I don't see any specific reasons for holding on to a traditional view of how medicine has been practiced, so I think experiments should be tried to see if they work," said Rosamond Rhodes, MD, Director of Bioethics Education at The Mount Sinai Hospital. -Dr. Cameron K. Rokhsar, Assistant Clinical Professor Dermatology, The Mount Sinai Hospital -Dr. Rosamond Rhodes, Director of Bioethics Education, The Mount Sinai Hospital Learn more: http://www.medpagetoday.com/Dermatology/GeneralDermatology/46799

News-Medical – July 18 Large Proportion of PLHA in US are not Sufficiently Engaged in Care and not Taking ART - Regular attendance at HIV primary care visits and high adherence to antiretroviral therapy (ART) are vital for people living with HIV/AIDS (PLHA), as these health behaviors lead to lowered rates of morbidity and mortality, increased quality of life, and reducing the risk of HIV transmission to others. "Yet to achieve the goals of the National HIV/AIDS Strategy (NHAS), PLHA must attend regular health care appointments, initiate ART in a timely fashion, and remain on ART with high adherence through their lives," said Nadim Salomon, MD, Attending, Department of Medicine, Professor of Medicine, Mount Sinai Beth Israel. -Dr. Nadim Salomon, Attending, Department of Medicine, Professor of Medicine, Mount Sinai Beth Israel Learn more: http://www.news-medical.net/news/20140718/Large-proportion-of-PLHA-in-US-are-not-sufficiently- engaged-in-care-and-not-taking-ART.aspx Additional Coverage: Infection Control Today: http://www.infectioncontroltoday.com/news/2014/07/researchers-seek-out-persons-with-hiv- who-dont-take-medication-are-not-engaged-in-their-healthcare.aspx Science Daily: http://www.sciencedaily.com/releases/2014/07/140717095112.htm Medical Xpress: http://medicalxpress.com/news/2014-07-efforts-persons-hivaids-medication-engaged.html Health Canal: http://www.healthcanal.com/infections/hiv-and-aids/53210-nyu-researchers-expand-efforts-to-seek- out-persons-with-hiv-aids-who-are-not-taking-medication-and-not-engaged-in-care.html Science Newsline: http://www.sciencenewsline.com/articles/2014071716150021.html Science Codex: http://www.sciencecodex.com/nyu_research_on_persons_w_hivaids_not_taking_medication_and_not_engaged_in_care- 137698

The Huffington Post – July 18 How to Improve Your Cholesterol and Cut Your Risk for Heart Disease – Laura Manning, MPH, RD, CDN Do you know your cholesterol levels? If not, you should. According to the Centers for Disease Control, high LDL ("bad") cholesterol is a key risk factor for heart disease, the leading cause of death for men and women in the United States. -Laura Manning, MPH, RD, CDN, Clinical Nutrition Coordinator, Department of Gastroenterology, Faculty Practice Associates, The Mount Sinai Hospital Learn More: http://www.huffingtonpost.com/mount-sinai-health-system/how-to-improve-your-chole_b_5592112.html

Naked Scientists – July 18 Gene Testing Issues Thanks to advances in technology, a day when we might each have our own personal genome at our fingertips is coming ever closer. “Genetic testing really ranges from single genetic tests for gene variants that we really know quite a lot about - a good example of that would be the BRCA1 and 2 gene variants that were strongly associated with risk of breast cancer - then you have other genetic tests for single gene variants which really, we use for research purposes where you're looking at single gene variants associated with a very slightly increased risk of a common complex disease like heart disease, lung cancer, that kind of thing,” said Saskia C. Sanderson, Adjunct Assistant Professor Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai. -Saskia C. Sanderson, Adjunct Assistant Professor Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai. Learn more: http://www.thenakedscientists.com/HTML/content/interviews/interview/1000790/

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: MountSinaiNewsNow Subject: Mount Sinai In The News - July 17, 2014 Date: Thursday, July 17, 2014 2:39:56 PM

In the News July 17, 2014

New York Times – July 17 Roche Reports Mixed Results in Trial of an Alzheimer’s Drug – Andrew Pollack Roche, the pharmaceutical company, on Wednesday reported mixed results in its latest trial of an Alzheimer’s drug. It said that while the drug did not slow progression of the disease over all, at the highest doses it did seem to delay a decline in mental ability in patients with mild cases of Alzheimer’s. “Long story short, we are still a long way from anything that could be approvable as therapy,” said Sam Gandy, PhD, Professor of Neurology and Psychiatry, and Associate Director of the Mount Sinai Alzheimer’s Disease Research Center at the Icahn School of Medicine at Mount Sinai. -Dr. Sam Gandy, Professor of Neurology and Psychiatry, Associate Director, Mount Sinai Alzheimer’s Disease Research Center, Icahn School of Medicine at Mount Sinai Learn more: http://www.nytimes.com/2014/07/17/business/roche-reports-mixed-results-in-trial-of-an- alzheimers-drug.html

Forbes – July 17 Hard Evidence We Can Slow Alzheimer’s By Exercising the Mind and Body – Matthew Herper Alzheimer’s disease is one of the most feared diagnoses among patients. It destroys people’s minds, their personalities, and the very essence of who they are. And once the disease has been diagnosed, there is nothing modern medicine can do to stop it. “For the past few years, physical exercise has been as good or better than anything that we can recommend for people with or at risk for cognitive decline. Would that we had a pill as good as that but we do not,” said Samuel Gandy, MD, PhD, Professor of Alzheimer's Disease Research, Professor of Neurology and Psychiatry, Associate Director of Alzheimer's Disease Research Center, and Chairman Emeritus of the National Medical and Scientific Advisory Council of the Alzheimer's Association. -Dr. Samuel Gandy, Professor of Alzheimer's Disease Research, Professor of Neurology and Psychiatry, Associate Director of Alzheimer's Disease Research Center, and Chairman Emeritus of the National Medical and Scientific Advisory Council of the Alzheimer's Association. Learn more: http://www.forbes.com/sites/matthewherper/2014/07/14/finally-hard-evidence-that- exercising-the-body-and-mind-can-slow-dementia/

Clinical Psychiatry News – July 17 ADHD Drug Works by Stimulating Brain’s Motivation-Reward System – Whitney McKnight Activity in the regions of the brain associated with motivation and reward correlated with clinical improvements in attention-deficit/hyperactivity disorder symptoms in adults given lisdexamfetamine dimesylate, the results of an imaging study have shown. "What we saw is that Vyvanse (lisdexamfetamine dimesylate) increases activity in the caudate and anterior cingulate, which then seems to show that the medication increases sensitivity to reward," said Stephanie Duhoux, PhD, Postdoctoral Fellow Psychiatry at the Icahn School of Medicine at Mount Sinai, in an interview about her poster presentation at a meeting of the American Society of Clinical Psychopharmacology -Dr. Stephanie Duhoux, Postdoctoral Fellow Psychiatry at the Icahn School of Medicine at Mount Sinai Learn more: http://www.clinicalpsychiatrynews.com/home/article/adhd-drug-works-by-stimulating- brains-motivation-reward-system/f6c8aa8a50a8d913d5cdb185afcd0393.html

Dermatology Times – July 17 Secukinumab Found Effective in Treating Psoriasis – Bill Gillette The results of two large phase 3 clinical trials suggest that the drug secukinumab (Novartis) is a remarkably effective treatment for moderate-to-severe plaque psoriasis. “Secukinumab achieves levels of clearing not reported in the past — even in patients who failed other biologics and systemic therapies. It is a breakthrough in the treatment of psoriasis,” said Mark G. Lebwohl, MD, Sol and Clara Kest Professor of Dermatology and Chair of the Kimberly and Eric J. Waldman Department of Dermatology at the Icahn School of Medicine at Mount Sinai. -Dr. Mark G. Lebwohl, Sol and Clara Kest Professor, Dermatology, Chair, Kimberly and Eric J. Waldman Department of Dermatology, Icahn School of Medicine at Mount Sinai Learn More: http://dermatologytimes.modernmedicine.com/dermatology-times/news/secukinumab- found-effective-treating-psoriasis?contextCategoryId=116

Oncology Nurse Advisor – July 17 Radiation-Induced Toxicity Risk in Prostate Cancer Predicted by Variations in Key Gene – Kathy Boltz, PhD Key genetic variants may affect how cancer patients respond to radiation treatments, according to a new study. The research team found that variations in the TANC1 gene are associated with a greater risk for radiation-driven side effects in prostate cancer patients, which include incontinence, impotence, and diarrhea. "Our findings, which were replicated in two additional patient groups, represent a significant step towards developing personalized treatment plans for prostate cancer patients," said Barry S. Rosenstein, PhD, Professor, Radiation Oncology, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, and lead investigatory on the study. -Dr. Barry S. Rosenstein, Professor, Radiation Oncology, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai Learn more: http://www.oncologynurseadvisor.com/radiation-induced-toxicity-risk-in-prostate-cancer- predicted-by-variations-in-key-gene/article/361114/

Time Warner Cable News / New York 1 – July 17 New York Hospitals Ranked High Nationally The Mount Sinai Hospital rated among best in the country on U.S. News and World Report’s Best Hospitals list. The hospital was ranked 16th on the national list from the publication. -The Mount Sinai Hospital Learn more: http://www.ny1.com/content/news/212278/city-hospitals-rank-highly-on-u-s--news--- world-report-list/ Additional Coverage: CBS News: http://www.cbsnews.com/news/u-s-news-and-world-report-ranks-best-hospitals/ Buffalo Business First: http://www.bizjournals.com/buffalo/news/2014/07/16/rpci-buff-general-named-among-top- hospitals.html News Medical: http://www.news-medical.net/news/20140716/Mount-Sinai-Hospital-earns-top-rankings-on-the-US- News-World-Reports-Best-Hospitals-Honor-Roll.aspx

Frequency – July 17 How to Regulate Blood Sugar – Jeffrey Mechanick, MD To help reduce the risk of serious health problems, Average Blood Sugar Level (A1C) over 2 – 3 months, should be 6.5 percent or less. Nearly half the people with diabetes are not at this goal. -Jeffrey Mechanick, MD, Clinical Professor of Medicine, Endocrinology, Diabetes and Bone Disease Learn more: http://www.frequency.com/video/aace-immediate-past-president-dr-jeffrey/181483735/-/5- 2803

Canarsie Courier – July 17 Flatbush Resident is Valedictorian of Phillips Beth Israel School of Nursing Rochel Kasirer, a resident of Flatbush, is cumma cum laude and valedictorian of the Class of 2014 of the Phillips Beth Israel School of Nursing. -Phillips Beth Israel School of Nursing [No web link available]

Cardiology Today – July 17 Groundbreaking Clinical Results for CoreValve May Transform Treatment of Aortic Stenosis At the American College of Cardiology Scientific Sessions in March, researchers reported for the first time that transcatheter aortic valve replacement was superior at 1 year to surgical aortic valve replacement in a patient population. “This was the first suggestion that there is a population of patients that could be treated with a [TAVR] device who might actually do better than patients treated with conventional surgery. That’s very provocative,” said David H. Adams, MD, Professor and System Chair Cardiothoracic Surgery, who presented the data at the ACC Scientific Sessions. -Dr. David Adams, Professor, Chair, Cardiothoracic Surgery, The Mount Sinai Hospital Learn more: http://www.healio.com/cardiology/intervention/news/print/cardiology-today/%7B2297b2fd- 4402-4e49-b41c-3087a3384d03%7D/groundbreaking-clinical-results-for-corevalve-may-transform- treatment-of-aortic-stenosis?page=0&Filter

MedPage Today – July 16 Acne App Takes Telemedicine to New Level – Parker Brown Using the PocketDerm app, patients send in pictures of their acne and receive a diagnosis from a licensed dermatologist. Prescriptions come through the mail. "I just think it's a very simplistic way to treat a medical condition, and they can't offer the broad scope of things,” said Cameron Rokshar, MD, Assistant Professor of Dermatology at The Mount Sinai Hospital. “What if the patient needs laser treatment for it? What if there's a hormonal issue that's causing the problem?" -Dr. Cameron Rokshar, Assistant Professor, Dermatology, The Mount Sinai Hospital Learn more: http://www.medpagetoday.com/Dermatology/GeneralDermatology/46799

HealthDay – July 17 Potassium Supplements May Help Some Heart Failure Patients Potassium supplements might boost the survival of heart failure patients who are already taking diuretic drugs, a new study suggests. "This study emphasizes the need for potassium supplementation with use of higher-dose loop diuretics," said Ajith Nair, MD, Assistant Professor of Medicine and Cardiology at The Mount Sinai Hospital. -Dr. Ajith Nair, Assistant Professor, Medicine and Cardiology, The Mount Sinai Hospital Learn more: http://consumer.healthday.com/circulatory-system-information-7/heart-failure-news- 753/potassium-supplements-may-help-some-patients-with-heart-failure-689792.html

Women’s Health – July 17 Eight Summer Skin-Care Mistakes You're Probably Making – Alison Goldman If you're not careful, the summer can mean sunburns and irritated tan lines. You know to avoid tanning beds, to wear lip balm with SPF, and reapply sunscreen regularly — but you might be making seasonal skin-care errors you're not even aware of. For example, "Shaving shouldn't be the first thing that you do [in the shower]," said Joshua Zeichner, MD, Director of Cosmetic and Clinical Research and Assistant Professor of Dermatology at The Mount Sinai Hospital. -Joshua Zeichner, MD, Director of Cosmetic and Clinical Research, Assistant Professor, Dermatology, The Mount Sinai Hospital Learn more: http://www.womenshealthmag.com/beauty/summer-skin-care

CBS Pittsburg – July 17 Cancer Patients Choosing Hypnosis Over Counseling – Maria Simbra Dealing with cancer is difficult both physically and emotionally, especially when the treatments start, but some cancer patients are now using a new tool to help them get through it. “They learned the skills that they needed to help themselves feel better over time and hopefully, improve their quality of life,” said Guy Montgomery, PhD, Director of the Integrative Behavioral Medicine Program and Associate Professor in the Department of Oncological Sciences, Division of Cancer Prevention and Control at The Mount Sinai Hospital. -Dr. Guy Montgomery, Director of the Integrative Behavioral Medicine Program and Associate Professor in the Department of Oncological Sciences, Division of Cancer Prevention and Control Learn more: http://pittsburgh.cbslocal.com/2014/07/16/cancer-patients-choosing-hypnosis-over- counseling/

The Jewish Voice – July 17 Losing Weight May Ease Hot Flashes, Study Finds – Kristen Fischer Slimming down may help ease the hot flashes that often accompany menopause, new research suggests. "Hot flashes can be debilitating for more than 50 percent of menopausal women," said Taraneh Shirazian, MD, Faculty, Department of Obstetrics, Gynecology and Reproductive Sciences, and Assistant Professor of Obstetrics, Gynecology and Reproductive Science. -Dr. Taraneh Shirazian, MD, Faculty, Department of Obstetrics, Gynecology and Reproductive Sciences, Assistant Professor Obstetrics, Gynecology and Reproductive Science Learn more: http://www.jewishvoiceny.com/index.php? option=com_content&view=article&id=7915:losing-weight-may-ease-hot-flashes-study-finds

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: MountSinaiNewsNow Subject: Mount Sinai In The News - July 16, 2014 Date: Wednesday, July 16, 2014 2:38:25 PM

In the News July 16, 2014

Crain’s New York Business – July 15 New York Hospitals Ranked High Nationally – Mark Fahey U.S. News and World Report Tuesday released its latest Best Hospitals rankings, with three New York hospitals among the 17 hospitals that made it onto the national Honor Roll by excelling in six or more specialties. The Mount Sinai Hospital ranked 16th on the national list, and 10th on the national list for cardiac care and heart surgery. -The Mount Sinai Hospital Learn more: http://www.crainsnewyork.com/article/20140715/HEALTH_CARE/140719941/new-york- hospitals-ranked-high-nationally

NBC New York Nightly News – July 16 U.S. News and World Report Best Hospitals U.S. News and World Report is out with its annual list of the nation’s top hospitals and several local facilities made the cut. Locally, The Mount Sinai Hospital ranked 16th on the national list. The publication bases the rankings largely on data on hospital performance such as patient survival rates, and resources. WPIX 11 also provided coverage of Mount Sinai’s inclusion in the rankings. -The Mount Sinai Hospital [No web link available]

Becker’s Hospital Review – July 16 500 People to Know in Healthcare Kumar Chatani is Senior Vice President of IT and Chief Information Officer of the Mount Sinai Health System. Mr. Chatani brings more than 30 years of IT experience to his role. Prior to his current position, he served as senior vice president of IT and CIO of The Mount Sinai Medical System. -Kumar Chatani, Senior Vice President, IT, Chief Information Officer, Mount Sinai Health System Learn more: http://www.beckershospitalreview.com/lists/500-people-to-know-in-healthcare.html

The Huffington Post – July 15 Immigration and Dying 9/11 Ground Zero Workers – Ryan Campbell A Mount Sinai report has found that 70 percent of the almost 10,000 Ground Zero workers surveyed had new or worsened respiratory illness symptoms since 9/11. Many of the illnesses associated with the breathing of the debris (such as various forms of cancer) will not manifest for over a decade. -The Mount Sinai Hospital Learn more: http://www.huffingtonpost.com/ryan-campbell/immigration-and-dying-911-ground-zero- workers_b_5588410.html

Health Leaders Media – July 15 Personalized Medicine Meets EHR Integration at Mt. Sinai – Scott Mace At The Mount Sinai Health System, a combination of personalized medicine, natural language processing, and clever integration with electronic health record software is allowing clinicians to adjust medication selection and dosages based on patients' genomic differences. The clever integration, invented at Mount Sinai, is the Clinical Implementation of Personalized Medicine through Electronic Health Records and Genomics platform, or CLIPMERGE for short. Heading up development of CLIPMERGE was Omri Gottesman, MD, Assistant Professor of Medicine (General Internal Medicine) at The Mount Sinai Hospital, focused on the translation and implementation of genomic and data-driven medicine into clinical practice. -Dr. Omri Gottesman, Assistant Professor, Medicine, General Internal Medicine, The Mount Sinai Hospital Learn more: http://www.healthleadersmedia.com/content/TEC-306371/Personalized-Medicine-Meets- EHR-Integration-at-Mt-Sinai##

The New York Post – July 15 Ancient Practice of Acupuncture Being Used for Modern Health Problems While acupuncture may be best known as a treatment for chronic pain, headaches and anxiety, practitioners are now using it to help alleviate the side effects of chemotherapy. Arya Nielsen, PhD, Director, Acupuncture Fellowship, Center for Health and Healing at Mount Sinai Beth Israel, has found that many trials show it helped patients with chemotherapy-induced vomiting and nausea. Dr. Nielsen said soldiers suffering from post-traumatic stress disorder (PTSD) are also helped by a combination acupuncture and cognitive behavioral therapy. -Dr. Arya Nielsen, Director, Acupuncture Fellowship, Center for Health and Healing at Mount Sinai Beth Israel [No web link available]

Mother Nature Network – July 15 The Surprising Secrets of 'Sex in the Wild' – Gerri Miller ‘Sex in the Wild’ is an entertaining, educational, explicit and scientifically stimulating look at how animals reproduce, airing on four successive Wednesdays on PBS beginning July 16. “I feel it is our responsibility, as scientists, to educate the public about science. TV documentaries are the perfect medium to do outreach science teaching, and PBS is the perfect channel as it is focused on delivering educational content,” said Joy S. Reidenberg, Professor in the Center for Anatomy and Functional Morphology at the Icahn School of Medicine at Mount Sinai, who is co-host of the program. -Dr. Joy S. Reidenberg, Professor, Center for Anatomy and Functional Morphology, Medical Education, Icahn School of Medicine at Mount Sinai Learn more: http://www.mnn.com/earth-matters/animals/stories/the-surprising-secrets-of-sex-in-the- wild

MedPage Today – July 15 Pregnancy Loss Linked to Later Heart Disease – Crystal Phend Miscarriages and stillbirths might be a marker for women at higher risk of developing heart disease later in life, an observational study suggested. “Physicians should now include stillbirth or miscarriage on their list of items to ask about in screening for cardiovascular disease,” said Roxana Mehran, MD, Professor of Medicine, Health Evidence and Policy, and Director of Interventional Cardiovascular Research and Clinical Trials at the Icahn School of Medicine at Mount Sinai, who was not involved in the study. -Dr. Roxana Mehran, Professor of Medicine, Evidence and Health Policy, Director of Interventional Cardiovascular Research and Clinical Trials, Icahn School of Medicine at Mount Sinai Learn more: http://www.medpagetoday.com/Cardiology/Prevention/46787

Refinery 29 – July 15 Will One Cookie Ruin Your Diet? – K. Aleisha Fetters Reintroducing even a little wheat into an otherwise wheat-free diet can lead to everything from gas, bloating, diarrhea, and abdominal pain to depression, anxiety, and anger. And, symptoms can persist for days to weeks after re-exposure. “The fear that a small splurge will turn into a complete fail is nothing new,” said Christopher Ochner, PhD, Assistant Professor of Pediatrics, Adolescent Medicine, and Psychiatry at the Icahn School of Medicine at Mount Sinai, and Director of Research Training and Development at the Mount Sinai Adolescent Health Center. But, as far as he’s concerned, it’s your mindset — not what’s lurking in your cookie — that determines when diets derail. -Dr. Christopher Ochner, Assistant Professor, Pediatrics, Adolescent Medicine, Psychiatry, Icahn School of Medicine at Mount Sinai, Director, Research Training and Development, Mount Sinai Adolescent Health Center Learn more: http://www.refinery29.com/paleo-diet#page-1

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: MountSinaiNewsNow Subject: Mount Sinai In The News - July 15, 2014 Date: Tuesday, July 15, 2014 3:26:22 PM

In the News July 14-15, 2014

New York Daily News – July 15 One Mother's Triumph: Having a Baby Late in Life – Heidi Evans According to a study by the Centers for Disease Control, there were 7,157 babies born to women 45-49 years old, and 600 babies born to women 50-54 years old in 2012. Advancements in fertility, harvesting eggs, and in vitro fertilization (IVF) make it possible. And obstetricians who specialize in high-risk pregnancies, like Joanne Stone, MD, Professor of Obstetrics, Gynecology, Reproductive Medicine, Director of the Maternal Fetal Medicine Fellowship, Perinatal Ultrasound, and Division Director of Maternal Fetal Medicine at the Icahn School of Medicine at Mount Sinai, make it safe. “Everything went great, she did amazing,” said Dr. Stone, who watched over Karen Moulding’s pregnancy for 39 weeks with frequent ultrasounds to follow fetal growth and assess fetal well-being. On May 13, Moulding delivered a healthy 5 lb. 4 oz. baby girl by Cesarean section. -Dr. Joanne Stone, Professor, Obstetrics, Gynecology Reproductive Medicine, Director, Maternal Fetal Medicine Fellowship, Perinatal Ultrasound, Division Director, Maternal Fetal Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.nydailynews.com/life-style/health/mother-triumph-article-1.1862028

New York Daily News – July 15 If You're Sick, City is the Place to be as New York's Hospitals Offer Array of Elite Medical Options, According to 2014-15 Rankings Released by U.S. News and World Report – Heidi Evans Three Manhattan hospitals were among the top 17 medical centers of more than 4,700 in the nation — making New York the only city in the country that can make such a boast, according to the 2014-15 rankings released Tuesday by U.S. News and World Report. The Mount Sinai Hospital is ranked third in the New York area. -The Mount Sinai Hospital Learn more: http://m.nydailynews.com/life-style/health/best-medical-care-new-york-elite-medical- options-article-1.1864824

Health Canal – July 14 Key Gene Variations Predict Patients’ Risk for Radiotherapy Side Effects Key genetic variants may affect how cancer patients respond to radiation treatments, according to a study, involving researchers at The University of Manchester, published recently in the journal Nature Genetics. The research team, which saw scientists from The Mount Sinai Hospital, found that variations in the TANC1 gene were associated with a greater risk of side effects after radiotherapy for prostate cancer. -The Mount Sinai Hospital Learn more: http://www.healthcanal.com/genetics-birth-defects/53017-key-gene-variations-predict- patients%E2%80%99-risk-for-radiotherapy-side-effects.html

Newsmax – July 10 New Psoriasis Drug Delivers Dramatic Results A new psoriasis drug delivered dramatic results in two clinical trials, perhaps heralding an effective new treatment for patients with the chronic skin disease. "Over a quarter of patients have not a dot of psoriasis left," said study co-author Mark G. Lebwohl, MD, Sol and Clara Kest Professor of Dermatology and Chair of the Kimberly and Eric J. Waldman Department of Dermatology at the Icahn School of Medicine at Mount Sinai. -Dr. Mark G. Lebwohl, Sol and Clara Kest Professor, Dermatology, Chair, Kimberly and Eric J. Waldman Department of Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://www.newsmax.com/Health-News/secukinumab-psoriasis-drug- skin/2014/07/10/id/581819/ Additional coverage: MSN Healthy Living: http://healthyliving.msn.com/health-wellness/new-psoriasis-drug-shows- promise-in-trials-1

News Observer – July 13 Science Briefs: Cancer Research, Eating Insects, and a New Mystery of the Universe Two genetic mutations in liver cells may drive tumor formation in intrahepatic cholangiocarcinoma (iCCA), the second most common form of liver cancer, according to research published in the July issue of the journal Nature. A team led by the Icahn School of Medicine at Mount Sinai and Harvard Medical School has discovered a link between the presence of two mutant proteins, IDH1 and IDH2, and cancer. “iCCA is resistant to standard treatments like chemotherapy and radiation,” said Josep Maria Llovet, MD, Director of the Liver Cancer Program, Division of Medicine at the Icahn School of Medicine at Mount Sinai, and an author of the report. “Understanding the molecular mechanism of the disease is the key to finding a treatment that works.” -Dr. Josep Maria Llovet, Director, Liver Cancer Program, Division of Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.newsobserver.com/2014/07/13/3991874/science-briefs.html

Forbes – July 11 How Long Should You Get Health Screenings? Women and men who’ve been screened for cancers and other conditions for decades sometimes resist stopping, even though they’ve reached the age where the harms — including anxiety over a falsely positive test — might outweigh the benefits. “The issue really differs by cancer,” said Albert Siu, MD, Professor and Chair, Geriatrics and Palliative Medicine and Professor of Health Evidence and Policy, Medicine and General Internal Medicine at the Icahn School of Medicine at Mount Sinai. He agrees that screening low-risk women past age 65 for cervical cancer “is of no benefit. There’s nothing to be gained.” -Dr. Albert Siu, Ellen and Howard C. Katz Chairman’s Chair, Brookdale Department of Geriatrics and Palliative Care, Icahn School of Medicine at Mount Sinai Learn more: http://www.forbes.com/sites/nextavenue/2014/07/11/how-long-should-aging-boomers-get- health-screenings/ Additional coverage: Next Avenue: http://www.nextavenue.org/article/2014-07/how-long-should-you-get-health-screenings

The Wall Street Journal – July 11 Yankees Mull Their Future Without Tanaka – Daniel Barbarisi Even though the Yankees have announced a six-week timetable for Masahiro Tanaka's return, the news that he will attempt to avoid reconstructive surgery on his elbow has left both Tanaka and the Yankees in limbo. Michael Hausman, MD, Professor and Interim Chair of Orthopaedics at The Mount Sinai Hospital, said the success of plasma therapy is a long shot. "There are anecdotal reports of success, but the evidence actually substantiating its efficacy is pretty slim," -Dr. Michael Hausman, Professor, Interim Chair, Orthopaedics, The Mount Sinai Hospital Learn more: http://online.wsj.com/articles/yankees-mull-their-future-without-tanaka-1405126519

YES Network – July 2014 2014 AHA Wall Street Run and Heart Walk from Running David Reich, MD, President of The Mount Sinai Hospital, and Horace W. Goldsmith Professor and Chair of Anesthesiology at The Mount Sinai Hospital, and Barbara Murphy, MD, Dean for Clinical Integration and Population Health, and Professor and Chair of Medicine and Nephrology at the Icahn School of Medicine at Mount Sinai, discussed the importance of all New Yorkers walking 30-minutes daily to remain heart healthy with the Running show on the YES Network for its broadcast report about the 2014 AHA Wall Street Run and Heart Walk. Nearly 300 Mount Sinai Health System employees participated in the June 18 event, helping to raise more than $30,000 to support the AHA’s future research initiatives. -Dr. David Reich, President, The Mount Sinai Hospital, Horace W. Goldsmith Professor, Chair, Anesthesiology, The Mount Sinai Hospital Learn more: https://www.youtube.com/watch?v=hzVWTmlfxvk

WCBS-TV – July 11 Five Tests to Save Your Life – Alice Gainer We take tests at the doctor’s office all the time, but there are actually a number of tests you can do at home that could help identify a serious illness like dementia or a future potential disability. Martin Goldstein, Medical Director of the Mount Sinai Cognitive Center at The Mount Sinai Hospital, said there is validity to some of these at-home tests to help detect early signs of several diseases. “They’re easy to do, quick, and patients can even do them in their own home,” said Dr. Goldstein. -Dr. Martin Goldstein, Medical Director of the Mount Sinai Cognitive Center, Mount Sinai Hospital Learn more: http://newyork.cbslocal.com/2014/07/11/seen-at-11-five-tests-to-save-your-life/

Reuters – July 10 Stress, Depression Raise Stroke Risk – Andrew Seaman A new study suggests that people who suffer from high levels of stress, hostility or depression may be more likely to have strokes. According to the Centers for Disease Control, more than 795,000 people in the U.S. have strokes every year. “We know the traditional risk factors for strokes but that chronic stress, depression, etc. has never been discussed as something modifiable,” says Carolyn Brockington, director of the Stroke Center at Mount Sinai St. Luke’s. She says prevention is key and it is worth it for patients and doctors to discuss chronic stress and other negative emotions. “People should also realize despite the prevention strategies, people do have strokes,” adding that people should seek help immediately if they believe they’re having a stroke. -Dr. Carolyn Brockington, Director, The Stroke Center, Mount Sinai Roosevelt and Mount Sinai St. Luke’s Learn more: http://www.philly.com/philly/health/Negative_emotions_raise_stroke_risk.html

HealthDay – July 14 iPads Can Trigger Nickel Allergies in Kids When an 11-year-old boy in San Diego developed a nasty skin allergy, doctors traced it to the nickel in his family's iPad. They also found a quick and easy solution – cover the iPad's metal surfaces with a form-fitting case. Gary Goldenberg, MD, Medical Director of the Dermatology Faculty Practice at The Mount Sinai Hospital, and Assistant Professor of Dermatology and Pathology at the Icahn School of Medicine at Mount Sinai, said that "nickel allergy is one of the most common allergies seen in dermatology. It may cause acute reactions, with itching, crusting and redness, as well as a chronic dermatitis with scaling and redness.” -Dr. Gary Goldenberg, Medical Director, Dermatology Faculty Practice, The Mount Sinai Hospital, Assistant Professor, Dermatology, Pathology, Icahn School of Medicine at Mount Sinai Learn more: http://consumer.healthday.com/respiratory-and-allergy-information-2/misc-allergy-news- 17/ipads-can-trigger-nickel-allergies-in-kids-689674.html

Nurse.com – July 14 Meet the 2014 NY/NJ GEM Award Winners – Tracey Boyd Janet Mackin, RN, EdD, Dean, Phillips Beth Israel School of Nursing, has been named a GEM Award winner in the Education and Mentorship category. She is well-known for student advocacy and passion and for providing an environment where both graduate and undergraduate students and faculty can thrive. -Janet Mackin, Dean, Phillips Beth Israel School of Nursing, Mount Sinai Beth Israel Learn more: http://news.nurse.com/article/20140714/NY01/140711003#.U8S7CLFhP1B

Medscape Multispecialty – July 14 Steroids in Advanced Cancer Don't Help Pain But Boost QOL – Roxanne Nelson For patients with advanced cancer, the addition of methylprednisolone to opioid therapy did not help control pain, but it did boost quality of life, according to results from a small randomized trial. This study "is a welcome addition to the science of palliative medicine, suggesting significant improvements in fatigue, appetite, and satisfaction with care after a week of corticosteroid therapy among advanced cancer patients already receiving opioid therapy for pain," said Diane Meier, MD, Professor of Geriatrics and Palliative Medicine and Director of the Center to Advance Palliative Care at the Icahn School of Medicine at Mount Sinai, who was not involved in the study. -Dr. Diane Meier, Professor, Geriatrics and Palliative Medicine, and Director, Center to Advance Palliative Care, Icahn School of Medicine at Mount Sinai Learn more: http://www.medscape.com/viewarticle/828140

Tech Times – July 11 Obesity, Sleep Loss Associated with Teens’ Excessive ‘Screen-Time’, CDC Says – Rebecca Kaplan A study of 12- to 15-year-olds found that of obese teens, 20 percent kept their screen time to under two hours a day, compared to 31 percent of their peers with a healthy body weight. "It's important to try to establish children's habits early in life," said Angela Diaz, MD, Professor of Pediatrics, Adolescent Medicine and Preventive Medicine at the Icahn School of Medicine at Mount Sinai and Director of the Mount Sinai Adolescent Health Center. "Try to create an environment where kids have choices other than TV and computers." -Dr. Angela Diaz, Professor, Pediatrics, Adolescent Medicine and Preventive Medicine, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Adolescent Health Center Learn more: http://www.techtimes.com/articles/10165/20140711/obesity-sleep-loss-associated-with- teens-excessive-screen-time-cdc-says.htm

MedPage Today – July 13 Movie Plagues Not Entirely Claptrap – Michael Smith It's a recurring theme in movies – a plague threatens to kill us all and a few brave souls work tirelessly to prevent doom. "Fortunately," said Talia Swartz, MD, PhD, Assistant Professor of Medicine (Infectious Diseases) at the Icahn School of Medicine at Mount Sinai, "the notion of a scourge that could instantly wipe out humanity is not a likely event." -Dr. Talia Swartz, Assistant Professor, Medicine, Infectious Diseases, Icahn School of Medicine at Mount Sinai Learn more: http://www.medpagetoday.com/InfectiousDisease/GeneralInfectiousDisease/46735

MedPage Today – July 14 Striking a Nerve: 'Aware of How Much We Don't Know' – John Gever Last weekend, the American Academy of Neurology sponsored its first-ever conference devoted to concussions in sports. Among the attendees was Joshua Cohen, MD, Neurologist at the Headache Institute at Mount Sinai Roosevelt Hospital, who live-tweeted from the meeting in his @MyHeadacheDoc persona. -Dr. Joshua Cohen, Neurologist, The Headache Institute, Mount Sinai Roosevelt Learn more: http://www.medpagetoday.com/Neurology/HeadTrauma/46764

Healthline – July 14 Large Study Shows Organic Foods Are Safer, Healthier than Nonorganic – Julia Haskins In an effort to clear up the confusion, a new major study provides solid evidence for choosing organic over conventionally grown foods. “If you can afford to buy that stuff of course I would say to buy it, but it goes back to the individual person and knowing whether to prioritize,” said Kelly Hogan, RD, Clinical Dietician at The Mount Sinai Hospital. -Kelly Hogan, RD, Clinical Dietician, The Mount Sinai Hospital Learn more: http://www.healthline.com/health-news/organic-foods-healthier-than-nonorganic-071414

Healthline – July 14 Young People Ignore Summer Skin Cancer Risk at Their Peril – Sandra Levy Summer is a time to relax and enjoy the outdoors. But it's also a time when you are exposed to more sun and have an increased risk of skin cancer. Knowing how to protect yourself from the sun's harmful UV rays is crucial. “There’s a clear correlation between melanoma and tanning beds. It’s one of the main reasons melanoma is the number one skin cancer in women in their 20s,” said Hooman Khorasani, MD, Chief of Division of Mohs, Reconstructive, and Cosmetic Surgery, and Dermatology at the Icahn School of Medicine at Mount Sinai. -Dr. Hooman Khorasani, Chief of Division of Mohs, Reconstructive, and Cosmetic Surgery, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://www.healthline.com/health-news/young-people-ignore-skin-cancer-risk-071414

Allure – July 14 Top Dermatologists React to the Lululemon Bag Controversy – Catherine O’Neill For a lifestyle brand that outfits runners, yogis, and alfresco fitness enthusiasts, Lululemon left a lot of people shaking their heads at the brand's new shopping bags. "Despite publicity about the harmful effects of some sunscreen ingredients on the skin, there is no substantial supporting data. The currently available sunscreens are safe and effective and prevent not only premature aging of the skin but also skin cancers,” said Joshua Zeichner, MD, Assistant Professor of Dermatology and Director of Cosmetic and Clinical Research at The Mount Sinai Hospital. -Dr. Joshua Zeichner, Assistant Professor, Dermatology, Director, Cosmetic and Clinical Research, The Mount Sinai Hospital Learn more: http://www.allure.com/beauty-trends/blogs/daily-beauty-reporter/2014/07/dermatologists- react-to-lululemon.html Additional coverage: MSN Healthy Living: http://healthyliving.msn.com/health-wellness/skin/top-dermatologists-react-to- the-lululemon-bag-controversy

Beauty World News – July 14 Rosacea Triggers, Treatment, Acne and Redness: Skin Care and Makeup Tips from a Medical Pro – Kim West What you think is a major breakout could actually be diagnosed as rosacea, a skin condition that affects over 16 million Americans. "Even though the exact cause of rosacea is still unknown, the basic process involves the inflammation of the servacious glands," said Bruce Katz, MD, Clinical Professor of Dermatology at The Mount Sinai Hospital. "Some triggers of rosacea include extremes in weather, exercise, and hot beverages. Pretty much anything that causes the blood vessels to dilate." -Dr. Bruce E. Katz, Clinical Professor, Dermatology, The Mount Sinai Hospital Learn more: http://www.beautyworldnews.com/articles/10387/20140714/rosacea-triggers-acne-redness- skin-care-makeup-tips-from-a-medical-pro-facial-redness-pimples-zits-bad-acne-chronic-rosacea- treatment-cures-cream-triggers-skin-care-tips-dermatologist.htm

EmpowHer – July 14 Nipple Tattoos are Reconstructing Areolas for Mastectomy Patients – Michele Blacksberg Having breast cancer surgery can greatly affect a woman’s sense of herself. Nipple-sparing surgery is available to some women but not for those who have large tumors or tumors that are close to the nipple. Skin grafts to create a new nipple are less popular since “most patients don’t want to have another surgery and another scar,” said Leo Keegan, MD, Assistant Clinical Professor of Surgery at the Icahn School of Medicine at Mount Sinai. -Dr. Leo Keegan, Assistant Clinical Professor, Surgery, Icahn School of Medicine at Mount Sinai Learn more: http://www.empowher.com/cancer/content/nipple-tattoos-are-reconstructing-areolas- mastectomy-patients

MSN Healthy Living (from HealthDay) – July 10 Losing Weight May Ease Hot Flashes, Study Finds – Kristen Fischer Slimming down may help ease the hot flashes that often accompany menopause, new research suggests. “Hot flashes can be debilitating for more than 50 percent of menopausal women,” said Taraneh Shirazian, MD, Director of Global Women’s Health and Assistant Professor of Obstetrics, Gynecology and Reproductive Science at The Mount Sinai Hospital. About one-third of menopausal women experience more than 10 hot flashes a day, and she added that hot flashes are more common in obese women. -Dr. Taraneh Shirazian, Director, Global Women’s Health, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, The Mount Sinai Hospital Learn more: http://healthyliving.msn.com/health-wellness/women/losing-weight-may-ease-hot-flashes- study-finds-1

New York Daily News – July 13 Daily Checkup: New Medications Offer Hepatitis Patients a Much Better Chance at Cure – Katie Charles Globally, hepatitis ranks as the eighth most common cause of death — but the newest medications offer more and more patients the possibility of not just treatment, but a cure. “Hepatitis is a general term for inflammation of the liver, which can be caused by a variety of things: alcohol, drugs, and viruses,” said Douglas Dieterich, MD, Professor of Medicine (Liver Diseases) at the Icahn School of Medicine at Mount Sinai. “The exciting new development is that just about every patient with hepatitis C is a candidate for the latest generation of drugs, which offer treatment and cure with almost no side effects.” -Dr. Douglas Dieterich, Professor, Medicine, Liver Diseases, Icahn School of Medicine at Mount Sinai Learn more: http://www.nydailynews.com/life-style/health/daily-checkup-lowdown-hepatitis-article- 1.1857630

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: MountSinaiNewsNow Subject: Mount Sinai In The News - July 11, 2014 Date: Friday, July 11, 2014 12:40:54 PM

In the News July 11, 2014

WNYC & The New York Times / The Takeaway – July 9 Crystal Miller: 28 Years Old and Battling Breast Cancer Over the past 30 years, researchers have found a widening survival divide between black and white women diagnosed with breast cancer in the United States. Crystal Miller is a nurse at The Mount Sinai Hospital, and does data management and research on cancer for a living. Being informed and aware enabled her to find the lump in her breast herself, prior to the age that women generally begin receiving mammograms. -Crystal Miller, RN, BSN, MPD-RC Data Monitor, The Mount Sinai Hospital Learn more: http://www.thetakeaway.org/story/under-her-skin-meet-crystal-miller/

Forbes – July 10 FDA Places Clinical Hold On Phase 3 Trial of Novel Anticoagulant – Larry Husten Regado Biosciences announced today that the FDA had placed a “clinical hold” on patient enrollment and dosing in the REGULATE-PCI trial, which is testing the Revolixys anticoagulation system. REGULATE-PCI is a phase 3 trial comparing Revolixys to bivalirudin in 13,000 patients undergoing PCI. Roxana Mehran, MD, Professor of Medicine, Health Evidence and Policy, and Director of Interventional Cardiovascular Research and Clinical Trials at the Icahn School of Medicine at Mount Sinai, is one of the principle investigators of the trial. -Dr. Roxana Mehran, Professor of Medicine, Evidence and Health Policy, Director of Interventional Cardiovascular Research and Clinical Trials, Icahn School of Medicine at Mount Sinai Learn more: http://www.forbes.com/sites/larryhusten/2014/07/10/fda-places-clinical-hold-on-phase-3- trial-of-novel-anticoagulant/

ASCO Post – July 10 The More Things Change, the More They Stay the Same – James F. Holland, MD The ASCO Annual Meeting in June confirmed — and expanded — the excitement of the oncology community about molecular medicine and its future. With all this new hype and high hope for cancer cures, patients who are diagnosed today have higher expectations. As a result, doctor-patient communication has become an even more important part of treatment that cannot be replaced by a computer screen. -Dr. James F. Holland, Professor, Medicine, Hematology and Medical Oncology, Oncological Sciences, Neoplastic Diseases, Icahn School of Medicine at Mount Sinai Learn more: http://www.ascopost.com/issues/july-10,-2014/the-more-things-change,-the-more-they- stay-the-same.aspx

ASCO Post – July 10 Raja Flores, MD Named Chair of New Thoracic Surgery Department The Mount Sinai Health System has created a new academic Department of Thoracic Surgery at the Icahn School of Medicine at Mount Sinai. Raja M. Flores, MD, is the Founding Chairman of the Department for the Mount Sinai Health System. Dr. Flores, the Steven and Ann Ames Professor in Thoracic Surgery, will lead an established team of thoracic surgeons, as well as a broader coalition of newly recruited physicians and scientists, across the Health System. The Department will provide clinical care, conduct research, and offer educational activities focused on acquired and congenital diseases of the thoracic cavity, including the lungs, esophagus, and chest wall. -Dr. Raja M. Flores, Founding Chairman, Thoracic Surgery Department, Icahn School of Medicine at Mount Sinai http://www.ascopost.com/issues/july-10,-2014/raja-flores,-md,-named-chair-of-new-thoracic-surgery- department-at-mount-sinai.aspx

My Fox New York – July 10 Autism Study Seeks Brain Tissue Donations – Dan Bowens The numbers are staggering: 1 in 68 kids are now diagnosed with autism. But researchers at The Mount Sinai Hospital are hoping to unlock the mystery behind the disorder. A lab called Autism BrainNet is collecting brains for study, and Patrick Hof, Vice-Chair of the Fishberg Department of Neuroscience, Friedman Brain Institute, and Seaver Autism Center, and Professor of Neuroscience, Ophthalmology, and Geriatrics and Palliative Care at the Icahn School of Medicine at Mount Sinai, will lead a team at Mount Sinai that will contribute to the lab’s work. He said that dissecting the structure of a brain can help unlock some autism features like repetitive behaviors and difficulties in social settings. -Dr. Patrick Hof, Vice-Chair, Fishberg Department of Neuroscience, Friedman Brain Institute, Seaver Autism Center, Professor, Neuroscience, Ophthalmology, Geriatrics and Palliative Care, Icahn School of Medicine at Mount Sinai Learn more: http://www.myfoxny.com/story/25992430/autism-study-seeks-brain-tissue-donations

Brooklyn Daily – July 10 Standing O is at it Again! – Joanna DelBuono Michael Mattia, PT, DPT, MS, MHA, is the new president-elect of the New York Physical Therapy Association. In addition, Dr. Mattia is the Director of Rehabilitation Therapies at Mount Sinai Beth Israel Brooklyn. -Dr. Michael Mattia, Director, Rehabilitation Therapies, Mount Sinai Beth Israel Brooklyn Learn more: http://www.brooklyndaily.com/stories/2014/28/all-standingo-main-2014-07-11- bd_2014_28.html

Real Simple – July 2014 This is Only a Medical Test When it comes to medical testing, many adults are too nervous to show up. In a 2012 study published in the Journal of Health Communication, about half of the people surveyed said that they had not wanted to hear health information at some point in the past and 30 percent said they had avoided it. The timing and effectiveness of the mammogram is still debated. “You’ll also ease discomfort by scheduling your test right before or during your period, when breasts tend to be tender,” said Laurie Margolies, MD, Associate Professor of Radiology at The Mount Sinai Hospital. -Dr. Laurie Margolies, Associate Professor, Radiology, The Mount Sinai Hospital [No web link available]

HealthDay – July 10 Losing Weight May Ease Hot Flashes, Study Finds – Kristen Fischer Slimming down may help ease the hot flashes that often accompany menopause, new research suggests. “Hot flashes can be debilitating for more than 50 percent of menopausal women,” said Taraneh Shirazian, MD, Director of Global Women’s Health and Assistant Professor of Obstetrics, Gynecology and Reproductive Science at The Mount Sinai Hospital. About one-third of menopausal women experience more than 10 hot flashes a day, and she added that hot flashes are more common in obese women. -Dr. Taraneh Shirazian, Director, Global Women’s Health, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, The Mount Sinai Hospital Learn more: http://consumer.healthday.com/vitamins-and-nutrition-information-27/dieting-to-lose- weight-health-news-195/losing-excess-weight-may-help-ease-hot-flashes-689649.html

Red Orbit – July 10 People Increasingly Drawn To YouTube for Skin Cancer Information – Brett Smith While YouTube might be a popular destination for viral videos and sports highlight reels, it’s also useful for raising awareness of skin cancer and prevention techniques, according to a news report in the Dermatology Online Journal. Mount Sinai Health System, which sent dermatologists to the Aspen Ideas Festival, said the festival made for the ideal screening location, given its given high altitude, thinner atmosphere, and higher levels of UV radiation. “Skin cancer is the most common form of cancer in the world, but also one of the most preventable and treatable forms,” said Mark G. Lebwohl, MD, Sol and Clara Kest Professor of Dermatology and Chair of the Kimberly and Eric J. Waldman Department of Dermatology at the Icahn School of Medicine at Mount Sinai. -Dr. Mark G. Lebwohl, Sol and Clara Kest Professor, Dermatology, Chair, Kimberly and Eric J. Waldman Department of Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://www.redorbit.com/news/health/1113188830/youtube-successful-skin-awareness-tool- 07101/

News-Medical – July 11 Palliative Care Delivered Early during Hospitalization can Cut Costs for Critically Ill Patients Palliative care delivered early during hospitalization can help cut costs for critically ill patients, finds a new study in Health Services Research. Palliative care is a "fairly new medical specialty that has proven to substantially improve patient outcomes when it's delivered alongside routine treatments," said R. Sean Morrison, MD, Professor of Geriatrics and Palliative Medicine, Co-Director of the Patty and Jay Baker National Palliative Care Center, and Director of the Lilian and Benjamin Hertzberg Palliative Care Institute at The Mount Sinai Hospital. -Dr. R. Sean Morrison, Professor, Geriatrics and Palliative Medicine, Co-Director, Patty and Jay Baker National Palliative Care Center, Director of the Lilian and Benjamin Hertzberg Palliative Care Institute, The Mount Sinai Hospital Learn more: http://www.news-medical.net/news/20140711/Palliative-care-delivered-early-during- hospitalization-can-cut-costs-for-critically-ill-patients.aspx

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: MountSinaiNewsNow Subject: Mount Sinai In The News - July 10, 2014 Date: Thursday, July 10, 2014 1:03:14 PM

In the News July 10, 2014

The New York Times – July 9 In Small Trials, Two Drugs Go Far in Soothing Symptoms of Eczema and Psoriasis New drugs that block highly specific parts of the immune system are showing remarkable promise in treating two maddening skin diseases, eczema and psoriasis, according to papers published Wednesday in a leading medical journal. For psoriasis, a drug being developed by Novartis proved to be highly effective in late-stage clinical trials in clearing the skin of the characteristic patchy red plaques, according to another paper also published in the medical journal. “This is a very small part of the immune system that is hit and it appears from the results that it is the part of the immune system you have to hit to get rid of psoriasis,” said Mark G. Lebwohl, MD, Sol and Clara Kest Professor of Dermatology and Chair of the Kimberly and Eric J. Waldman Department of Dermatology at the Icahn School of Medicine at Mount Sinai, and an author of the paper. -Dr. Mark G. Lebwohl, Sol and Clara Kest Professor, Dermatology, Chair, Kimberly and Eric J. Waldman Department of Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://www.nytimes.com/2014/07/10/business/drugs-show-promise-in-treating-eczema- and-psoriasis-in-trials.html?_r=0 Additional coverage: HealthDay: http://consumer.healthday.com/diseases-and-conditions-information-37/misc-diseases-and- conditions-news-203/new-psoriasis-drug-shows-promise-in-trials-689622.html MedPage Today: http://www.medpagetoday.com/Dermatology/Psoriasis/46691 Healthline: http://www.healthline.com/health-news/new-psoriasis-drug-effective-two-clinical-trials- 070914

Counsel and Heal – July 10 Study Hints a Treatment for Liver Cancer through Gene Mutation – Kamal Nayan Two genetic mutations in liver cells may drive tumor formation in intrahepatic cholangiocarcinoma (iCCA), the second most common form of liver cancer, according to a new study. "iCCA is resistant to standard treatments like chemotherapy and radiation," said Josep Maria Llovet, MD, Director of the Liver Cancer Program, Division of Medicine at the Icahn School of Medicine at Mount Sinai, and contributing author. "Understanding the molecular mechanism of the disease is the key to finding a treatment that works." -Dr. Josep Maria Llovet, Director, Liver Cancer Program, Division of Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.counselheal.com/articles/10395/20140709/study-hints-treatment-liver-cancer- through-gene-mutation.htm Additional coverage: Domain-B: http://www.domain-b.com/technology/Health_Medicine/20140709_treatment.html Med India: http://www.medindia.net/news/gene-mutation-may-help-drive-formation-of-tumors-in- liver-cancer-138500-1.htm New Kerala: http://www.newkerala.com/news/2014/fullnews-78973.html News-Medical: http://www.news-medical.net/news/20140708/Genetic-mutations-in-liver-cells-may- drive-tumor-formation-in-intrahepatic-cholangiocarcinoma.aspx Knoxville Times: http://www.knoxvilletimes.com/index.php/sid/223617479/scat/2411cd3571b4f088 Science Daily: http://www.sciencedaily.com/releases/2014/07/140708131704.htm Science World Report: http://www.scienceworldreport.com/articles/15927/20140710/genetic-mutatation- liver-cell-key-reason-cancer.htm Bionity: http://www.bionity.com/en/news/149079/gene-mutation-may-lead-to-treatment-for-liver- cancer.html?u3o70e00qnm0q000icqc0uby13=

Everyday Health – July 9 Managing Sensory Symptoms of Multiple Sclerosis – Chris Iliades Some of the most distressing and even frightening symptoms of multiple sclerosis are sensory disturbances – sensations that can run the gamut from numbness to tingling to burning pain. They're also common. “People with MS experience three basic types of sensory symptoms,” said Fred Lublin, MD, Professor of Neurology at the Icahn School of Medicine at Mount Sinai, and Director of the Corinne Goldsmith Dickinson Center for Multiple Sclerosis at The Mount Sinai Health System. "Loss of sensation causes numbness, abnormal sensation can cause tingling, painful sensation feels like burning," he says. -Dr. Fred Lublin, Professor, Neurology, Icahn School of Medicine at Mount Sinai, Director, Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Mount Sinai Health System Learn more: http://www.everydayhealth.com/news/managing-sensory-symptoms-multiple-sclerosis/

Medical Express – July 7 Task Force: Healthy Adults don’t need Routine Carotid Artery Screening The U.S. Preventive Services Task Force says routine screening for carotid artery stenosis should is not advised for healthy adults. The final recommendation from the influential panel of health experts said it sees potential downsides, including unnecessary follow-up testing and surgeries that could cause serious harms, including stroke, cardiac events or death. "In an era of widely available medical testing, it is becoming increasingly clear that more tests do not always add up to better patient health," said Abigail Chen, MD, an Internist at Mount Sinai Beth Israel. -Dr. Abigail Chen, Department of Internal Medicine, Mount Sinai Beth Israel Learn more: http://medicalxpress.com/news/2014-07-experts-routine-screening-narrowed-neck.html

Examiner – July 9 Jessica Alba and Jessica Biel stay Sleek with CrossFit and Paleo Low Carb Diet – Joanne Eglash CrossFit and a low-carb diet, especially a Paleo-style one are preferred by both Jessica Alba and Jessica Biel. “Most people could probably afford to eat fewer refined grains and carbs,” said Rebecca Solomon, MS, RD, Director of Clinical Nutrition at Mount Sinai Beth Israel. However, she feels that foods excluded from a Paleo diet "are some of the healthiest foods around. Why can’t we have dairy? You could actually lose nutrients eating this way," she warned. -Rebecca Solomon, MS, RD, CDN, Director of Clinical Nutrition, Mount Sinai Beth Israel Learn more: http://www.examiner.com/article/jessica-alba-and-jessica-biel-stay-sleek-with-crossfit-and- paleo-low-carb-diet

Media Health Leaders – July 9 Hospitals Hop on World Cup Bandwagon – Marianne Aiello With the world's eyes on the soccer competition in Brazil, healthcare organizations are jumping at the chance to use the tournament's momentum to promote their services and positive population health messages. Some hospitals and health systems have taken it a step further, opening World Cup viewing parties to the community in an effort to reach potential patients. The Mount Sinai Hospital tweeted an invite to community members to stop by its facility to watch the game on July 1 and receive a free skin cancer screening while they're at it. -The Mount Sinai Hospital Learn more: http://www.healthleadersmedia.com/content/MAR-306220/Hospitals-Hop-on-World-Cup- Bandwagon

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: MountSinaiNewsNow Subject: Mount Sinai In The News - July 9, 2014 Date: Wednesday, July 09, 2014 2:20:41 PM

In the News July 9, 2014

CBS News – July 8 Over-Scheduling Kids may be Detrimental to their Development – Barbara Bronson Gray A new study suggests that kids may need a little more latitude with their free time instead of having their days packed with lessons, sports and structured activities. Caroline Martinez, MD, Assistant Clinical Professor of Pediatrics at the Icahn School of Medicine at Mount Sinai, said that executive function includes a broad range of thinking skills that include planning, problem-solving, making decisions and regulating thoughts and actions. -Dr. Caroline Martinez, Assistant Clinical Professor, Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: http://www.cbsnews.com/news/over-scheduling-kids-may-be-detrimental-to-their- development/

CBS News – July 7 First Patient Takes ReWalk Robotic Exoskeleton Home An autoimmune disease left retired U.S. Army sergeant Theresa Hannigan paralyzed three years ago, but now she can stand up and walk again, as the first patient in the country to use the wearable robotic exoskeleton ReWalk at home. Hannigan and 13 other patients have learned to use the system, studied at The Mount Sinai Hospital and the James J. Peters VA Medical Center. "Almost all the subjects have lost fat," said one of the project researchers, Ann Spungen, MD, an Associate Professor of Medicine, Teaching Assistant of Rehabilitation Medicine at The Mount Sinai Hospital. "We have also had improvements in patient-reported pain and quality of life." -Dr. Ann Spungen, Associate Professor, Medicine, Teaching Assistant, Rehabilitation Medicine, The Mount Sinai Hospital Learn more: http://www.cbsnews.com/news/first-patient-takes-rewalk-robotic-exoskeleton-home/

Care Diary – July 8 Caregiver and Physician Conversation with Jeffrey Levine, MD – Margery Pabst How can positive images help people in this country, particularly those who are ill and those who care for them? Jeffrey Levine, MD, a Geriatrician in the Department of Medicine at Mount Sinai Beth Israel, and professional photographer, has amassed what he calls a visual encyclopedia of aging. Dr. Levine said he photographs hands, feet, eyes, wrinkles, different parts of the body and different diseases related to aging, and shares them online and in person, in part to help change the public’s perception of older people. -Dr. Jeffrey Levine, Geriatrician, Department of Medicine, Mount Sinai Beth Israel Learn more: http://www.ecarediary.com/CPCRadioShow.aspx

HealthDay – July 8 Kids Still Getting Too Much 'Screen Time': CDC U.S. teenagers are still spending hours in front of the TV and computer every day – despite years of expert advice that kids' "screen time" should be limited, a new government study finds. "It's important to try to establish children's habits early in life," said Angela Diaz, MD, Professor of Pediatrics, Adolescent Medicine and Preventive Medicine at the Icahn School of Medicine at Mount Sinai and Director of the Mount Sinai Adolescent Health Center. "Try to create an environment where kids have choices other than TV and computers." -Dr. Angela Diaz, Professor, Pediatrics, Adolescent Medicine and Preventive Medicine, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Adolescent Health Center Learn more: http://consumer.healthday.com/kids-health-information-23/adolescents-and-teen-health- news-719/u-s-kids-still-getting-too-much-screen-time-cdc-689571.html

Genome Web – July 7 Natera, Mount Sinai Partner on Genetic Carrier Screening Test Natera and the Mount Sinai Genetic Testing Laboratory today announced a partnership to offer Natera's genetic carrier screening test. The Mount Sinai Genetic Testing Laboratory is part of the Icahn School of Medicine at Mount Sinai and offers screening tests for more than 100 disorders. Genetic screening is performed to determine whether an individual is a carrier for certain recessive genetic disorders. -Icahn School of Medicine at Mount Sinai Learn more (Subscription required): http://www.genomeweb.com//sequencing/natera-mt-sinai-partner- genetic-carrier-screening-test

Woman’s Day – July 7 Your Healthiest Summer Ever – Betsy Stephens When you're between rest stops on a road trip, you end up "holding it" more than you normally would. This might not seem like a big deal, but the longer urine sits in your bladder, the more likely it is to pick up bacteria and cause an infection, according to Taraneh Shirazian, MD, Director of Global Women’s Health and Assistant Professor of Obstetrics, Gynecology and Reproductive Science at The Mount Sinai Hospital. Additionally, according to Debra Wattenberg, MD, Associate Professor of Dermatology at The Mount Sinai Hospital, if you start to feel a little pressure or burning when you urinate, try heading off a full-blown infection by taking over-the-counter cranberry tablets twice a day. -Dr. Taraneh Shirazian, Director, Global Women’s Health, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, The Mount Sinai Hospital -Dr. Debra Wattenberg, Associate Professor, Dermatology, The Mount Sinai Hospital Learn more: http://www.womansday.com/health-fitness/conditions-diseases/healthiest-summer

Philly.com – July 8 Seven ‘Healthy’ Foods that are making you Fat – Kelly O’Shea Some so-called healthy ingredients can do some real damage on your waistline if you overuse them. For example, two tablespoons of coconut oil contain about 200 calories and 16 grams of artery-clogging saturated fat. According to Jaclyn London, MS, RD, CDN, Senior Clinical Dietician at The Mount Sinai Hospital, that’s 80 percent of your recommended daily value of fats. -Jaclyn London, MS, RD, CDN, Senior Clinical Dietitian, The Mount Sinai Hospital Learn more: http://www.philly.com/philly/blogs/goal-getter-nutrition/7-healthy-foods-that-are-making- you-fat.html

Voice of America – July 8 How Effective are Those Fake World Cup Injuries? – Adam Phillips Anyone watching soccer's World Cup is familiar with the head-knocking, pushing, elbowing and even biting that occurs on the field — and how players on the receiving end of those maneuvers sometimes react in dramatic, seemingly exaggerated ways. "It’s like a boxer who may hug his opponent to buy some breathing time or goes down on a punch and waits until just before the count of 10 to get up so they can have some breathing time,” said Harris Stratyner, MD, Associate Clinical Professor of Psychiatry at The Mount Sinai Hospital. -Dr. Harris Stratyner, Associate Clinical Professor, Psychiatry, The Mount Sinai Hospital Learn more: http://www.voanews.com/content/world-cup-injuries-real-or-faked/1953580.html

Health Data Management – July 8 At Mount Sinai, Patient Itineraries Ease Worries – Joseph Goedert The Mount Sinai Hospital is using iPads in five nursing units to enable patients to access educational materials and entertainment options, as well as see their itinerary of procedures. “Patients like to know when tests are being done and blood is being drawn,” said Carol Porter, RN, Senior Vice President and Chief Nursing Officer of The Mount Sinai Hospital. “Patients completing a built-in short questionnaire gave the tablets 4.75 out of 5.0 stars,” said Michael DeCarlo, Director of Innovation and Analytics at The Mount Sinai Hospital. -Carol Porter, Senior Vice President, Chief Nursing Officer, The Mount Sinai Hospital -Michael DeCarlo, Director, Innovation and Analytics, The Mount Sinai Hospital Learn more: http://www.healthdatamanagement.com/news/at-mount-sinai-patient-itineraries-ease- worries-48380-1.html Additional coverage: Mobi Health News: http://mobihealthnews.com/34693/mt-sinai-offers-ipads-to-patients-to-track-their- stay/

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: MountSinaiNewsNow Subject: Mount Sinai In The News - July 8, 2014 Date: Tuesday, July 08, 2014 11:10:33 AM

In the News July 8, 2014

The Washington Post – July 7 What to know before you Spray your Lawn with Pesticides – Amanda Mascarelli Though the goal may be to make these green spaces more pleasant places to play — fewer bugs, fewer weeds — spraying pesticides may not be as safe as you assume. Most people are “not aware of the hazards that the unthinking use of pesticides poses to their children,” said Philip Landrigan, MD, Dean for Global Health, Chair and Ethel H. Wise Professor in the Department of Preventive Medicine at the Icahn School of Medicine at Mount Sinai, Director of the Children’s Environmental Health Center at The Mount Sinai Hospital. Pesticides include herbicides to kill weeds and insecticides such as those sprayed to manage cockroaches and other pests. -Dr. Philip Landrigan, Dean for Global Health, Chair and Ethel H. Wise Professor, Department of Preventive Medicine, Icahn School of Medicine at Mount Sinai, Director, Children’s Environmental Health Center, The Mount Sinai Hospital Learn more: http://www.washingtonpost.com/national/health-science/what-to-know-before-you-spray- your-lawn-with-pesticides/2014/07/07/77d719a2-f63c-11e3-a606-946fd632f9f1_story.html

New York Times – July 6 Letter to the Editor: A Timely Diagnosis – Merle Myerson, MD The NBA should be commended for diagnosing Marfan Syndrome in Isaiah Austin at the NBA Combine and potentially saving his life. Perhaps more remarkable was that he had gone that far without a diagnosis. The American Heart Association has had recommendations in place since 2007 for the screening of athletes before they participate in competitive sports. There are 12 elements, and two include Marfan syndrome. One is a family history, and the other is “physical stigmata,” including arm span, height ratio, joint hypermobility, and facial and hand features. -Dr. Merle Myerson, Director, Cardiovascular Disease Prevention and Pre-Exercise Heart Screening Program, Mount Sinai St. Luke’s and Mount Sinai Roosevelt Learn more: http://www.nytimes.com/2014/07/06/sports/letters-to-the-editor.html?emc=eta1&_r=0

The New York Times – July 7 Woman in Custody After Leaving Baby on Subway Platform – Emma G. Fitzsimmons The subway train doors opened at the Columbus Circle station around noon on Monday, and a woman stepped out onto the platform pushing a stroller with a 6- or 7-month-old girl inside. Moments later, the police said, she stepped back into the train alone. The baby was unharmed and in stable condition at Mount Sinai St. Luke’s-Roosevelt on Monday night. -Mount Sinai Roosevelt Learn more: http://www.nytimes.com/2014/07/08/nyregion/baby-girl-is-abandoned-on-columbus-circle- subway-platform.html?_r=0 Additional coverage: WABC-TV: http://7online.com/news/baby-girl-found-abandoned-on-nyc-subway-platform/164990/ Gothamist: http://gothamist.com/2014/07/07/baby_abandoned_at_columbus_circles.php AM New York: http://www.amny.com/news/baby-abandoned-at-columbus-circle-subway-station- 1.8709640 CBS 2 New York: http://newyork.cbslocal.com/2014/07/07/baby-found-abandoned-at-columbus-circle- subway-station/

HealthDay – July 8 Kids on Tight Schedules May Lose Out A new study suggests that kids may need a little more latitude with their free time instead of having their days packed with lessons, sports and structured activities. Caroline Martinez, MD, Assistant Clinical Professor of Pediatrics at the Icahn School of Medicine at Mount Sinai, said that executive function includes a broad range of thinking skills that include planning, problem-solving, making decisions and regulating thoughts and actions. -Dr. Caroline Martinez, Assistant Clinical Professor, Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: http://consumer.healthday.com/kids-health-information-23/child-development-news- 124/do-highly-structured-days-hamper-development-of-kids-thinking-skills-689203.html

Healthline – July 7 More Teens Are Lighting Up Hookahs, Says Study – Sandra Levy American youth are giving thumbs down to smoking cigarettes, but their use of smoking hookah is climbing, suggesting more education is needed to inform the public about the health dangers of this alternative form of smoking. Andrew Ting, MD, Assistant Professor of Pediatrics, and Pulmonary, Critical Care and Sleep Medicine at the Icahn School of Medicine at Mount Sinai, said, “Pediatric lung specialists will always be worried when children and teenagers are inhaling substances of unknown provenance. Besides possibly triggering asthma attacks, the potential toxicity of these unregulated plant materials is of major concern.” -Dr. Andrew Ting, Assistant Professor, Pediatrics, Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.healthline.com/health-news/more-teens-smoking-hookah-070714

Yahoo! – July 3 Five High-Tech Cooking Gadgets – Amir Khan With a few kitchen gadgets, you can turn your kitchen into a healthy eating paradise that will not only help you trim your waistline, but also cut down on the money you would spend eating out. "There are a ton of resources on the Internet for slow cooker recipes," said Rebecca Solomon, MS, RD, Director of Clinical Nutrition at Mount Sinai Beth Israel. "It's one of the easiest ways to fit eating healthy into your busy schedule." -Rebecca Solomon, MS, RD, CDN, Director of Clinical Nutrition, Mount Sinai Beth Israel Learn more: http://news.yahoo.com/5-high-tech-cooking-gadgets-184339552.html

Real Simple – July 2014 Beauty with Brains – Rough Patch? Keratosis Pilaris creates pimply, sandpapery areas on the back of the arm. However, these areas can be smoothed over with a surprising hybrid skin-care strategy. “Excess keratin ends up getting trapped inside hair follicles and forming hard plugs that become raised and rough to the touch. These inflame the surrounding skin, which then turns red,” said Joshua Zeichner, MD, Assistant Professor of Dermatology and Director of Cosmetic and Clinical Research at The Mount Sinai Hospital. A super-rich body cream with lanolin, glycerin, or petroleum jelly, like Curel Ultra Healing Lotion, can help calm KP. -Dr. Joshua Zeichner, Assistant Professor, Dermatology, Director, Cosmetic and Clinical Research, The Mount Sinai Hospital [No web link available]

Drugs.com – July 8 Experts Reject Routine Screening for Narrowed Neck Arteries Routine screening for a narrowing of the neck arteries should not be done in healthy adults, according to a recommendation from the U.S. Preventive Services Task Force. Abigail Chen, MD, an Internist at Mount Sinai Beth Israel said, "As primary care doctors, we have a responsibility to our patients to recommend testing which has been shown to be helpful and not harmful. Our goal is not to do every test on every patient, but rather the right test for the right patient." The final recommendation was published in the July 7 online edition of the journal Annals of Internal Medicine. -Dr. Abigail Chen, Department of Internal Medicine, Mount Sinai Beth Israel Learn more: http://www.drugs.com/news/experts-reject-routine-screening-narrowed-neck-arteries- 52268.html

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: MountSinaiNewsNow Subject: Mount Sinai In The News - July 7, 2014 Date: Monday, July 07, 2014 1:27:57 PM

In the News July 7, 2014

The New York Times – July 3 Think Like a Doctor: Sugar-Free Solved! – Lisa Sanders A middle-aged woman who suddenly began to have episodes of confusion caused by low blood sugar had an insulinoma, an insulin-producing tumor of the pancreas. Ronald Tamler, MD, Associate Professor of Medicine, Endocrinology, Diabetes and Bone Disease, and Clinical Director of the Mount Sinai Diabetes Center at the Mount Sinai Health System, suspected that her first endocrinologist had been right, that the patient had an insulin-producing tumor. The doctor ordered an endoscopic ultrasound of the pancreas, which can pick up very small growths. They found a one-centimeter tumor, and it was removed a couple of weeks later. -Dr. Ronald Tamler, Associate Professor, Medicine, Endocrinology, Diabetes, Bone Disease, Clinical Director, Mount Sinai Diabetes Center, Mount Sinai Health System Learn more: http://well.blogs.nytimes.com/2014/07/03/think-like-a-doctor-sugar-free-solved/

Time Warner Cable News / New York 1 – July 4 Doctors Advise Patients to Trust Their Gut with Stomach Upset – Jill Urban If your regular upset stomach becomes irregular, though, it could be a sign of a problem. “Everybody has a pattern, the way they eat, their bowels, if I can be so frank," said James Marion, MD, Senior Faculty of Medicine (Gastroenterology). "And if it changes, if there has been any change in that pattern or, more seriously, if you've lost your appetite, there's been abdominal pain where before you didn't have abdominal pain, you have to pay attention to that." -Dr. James Marion, Senior Faculty, Medicine, Gastroenterology, Icahn School of Medicine at Mount Sinai Learn more: http://manhattan.ny1.com/content/lifestyles/211654/doctors-advise-patients-to-trust-their- gut-with-stomach-upset/

New York Daily News – July 7 Experts Look at the Facts Behind Diets Used by Stars Like Shailene Woodley, Pippa Middleton and Matt McConaughey With the Paleo Diet, meat, fish, eggs and poultry (ideally organic and grass-fed) are fair game, along with fruit (preferably berries), veggies (except nightshades, such as tomatoes and eggplants) and nuts (except for peanuts). “Most people could probably afford to eat fewer refined grains and carbs,” said Rebecca Solomon, MS, RD, Director of Clinical Nutrition at Mount Sinai Beth Israel. “But why can’t we have tomatoes? Those are some of the healthiest foods around. Why can’t we have dairy? You could actually lose nutrients eating this way.” -Rebecca Solomon, MS, RD, CDN, Director of Clinical Nutrition, Mount Sinai Beth Israel Learn more: http://www.nydailynews.com/life-style/eats/celeb-diets-experts-eye-science-behind-hype- article-1.1853896

Medscape Multispecialty – July 4 HEAT-PPCI in Print: 'It's Pretty Bloody Detailed' – Shelley Wood The HEAT-PPCI trial that caused such a sensation earlier this year is now published in The Lancet accompanied by two editorials and a comprehensive online appendix that should put to rest the many questions raised about this ground-breaking and controversial study in recent months. Roxana Mehran, MD, Professor of Medicine, Health Evidence and Policy, and Director of Interventional Cardiovascular Research and Clinical Trials at the Icahn School of Medicine at Mount Sinai, who was not involved in the study, said further trials should be done to verify the HEAT-PPCI trial findings, but that these could still be conducted with a more traditional prerandomization consent process. -Dr. Roxana Mehran, Professor of Medicine, Evidence and Health Policy, Director of Interventional Cardiovascular Research and Clinical Trials, Icahn School of Medicine at Mount Sinai Learn more: http://www.medscape.com/viewarticle/827877?src=rss

Medscape Multispecialty – July 4 HEAT-PPCI in Print: 'It's Pretty Bloody Detailed' – Shelley Wood A large phase 3 randomized trial testing a new "controllable" antithrombotic has been paused by the data safety and monitoring board (DSMB) for an unplanned review, the trial sponsor announced this week. Roxana Mehran, MD, Professor of Medicine, Health Evidence and Policy, and Director of Interventional Cardiovascular Research and Clinical Trials at the Icahn School of Medicine at Mount Sinai, who was not involved in the study, pointed out that mild-to-moderate allergic reactions were seen in the phase 2 clinical study of REG1, called RADAR. -Dr. Roxana Mehran, Professor of Medicine, Evidence and Health Policy, Director of Interventional Cardiovascular Research and Clinical Trials, Icahn School of Medicine at Mount Sinai Learn more: http://www.medscape.com/viewarticle/827873

HealthDay – July 2 Insulin Pumps May Outperform Daily Injections for Type 2 Diabetes: Study Insulin pumps provide better blood sugar control for adults with diabetes than multiple daily insulin injections, according to a new study. Gerald Bernstein, MD, Director of the Diabetes Management Program at the Friedman Diabetes Institute at Mount Sinai Beth Israel, believes that insulin pumps may be the future of diabetes care, but hurdles remain. Because of insurance-related "inhibitors in our health care system," use of the devices "has not become common practice in the U.S.," said Dr. Bernstein. -Dr. Gerald Bernstein, Director, Diabetes Management Program, Friedman Diabetes Institute, Mount Sinai Beth Israel Learn more: http://consumer.healthday.com/diabetes-information-10/misc-diabetes-news-181/insulin- pumps-may-outperform-daily-injections-for-type-2-diabetics-study-689432.html

MSN Healthy Living (from Women’s Health) – July 2014 14 Foods Nutritionists Never Eat – Robin Hilmantel Nutritionists may advise against eating processed and/or canned meat or cheese. "Processed and/or canned meat or cheese – particularly those that are made with additional thickeners, preservatives, sugar, or a high content of preservatives,” said Jaclyn London, MS, RD, CDN, Senior Clinical Dietician at The Mount Sinai Hospital. “Animal products (and food products in general) that have to sit on a shelf inherently require a decent amount of processing to protect against microbial growth and contamination.” -Jaclyn London, MS, RD, CDN, Senior Clinical Dietitian, The Mount Sinai Hospital Learn more: http://healthyliving.msn.com/nutrition/14-foods-nutritionists-never-eat

Women’s Health – July 4 How Bad Your Worst Beauty Habit Actually Is – Alison Goldman Quitting your beauty vice is a lot easier said than done. The thing is, though, some are bigger issues than others. "Makeup can clog the pores, leading to pimples. And it actually can cause irritation of the skin, leading to eczema,” said Joshua Zeichner, MD, Assistant Professor of Dermatology and Director of Cosmetic and Clinical Research at The Mount Sinai Hospital, in regards to falling asleep with makeup on. -Dr. Joshua Zeichner, Assistant Professor, Dermatology, Director, Cosmetic and Clinical Research, The Mount Sinai Hospital Learn more: http://www.womenshealthmag.com/beauty/bad-beauty-habits

University World News – July 4 Scientists Face Access Backlash over Facebook Research – Paul Voosen By manipulating the news feeds of thousands of Facebook users, without their knowing consent, researchers working with the goliath of social media found that they could spur a significant, if small, effect on people’s behavior in the world beyond bits. “The main consequence is that academics will be wary of collaborating with Facebook," said Michelle N. Meyer, MD, Assistant Professor of Bioethics at Icahn School of Medicine at Mount Sinai. Facebook, she added, "will not have an incentive to collaborate with researchers motivated by publications.” -Dr. Michelle N. Meyer, Assistant Professor, Bioethics, Icahn School of Medicine at Mount Sinai Learn more: http://www.universityworldnews.com/article.php?story=20140703084911339

New York Daily News – July 6 Daily Checkup: Summer's the Time for a Rise in Swimmer's Ear – Katie Charles Pool parties and beach vacations bring with them a summertime scourge: swimmer’s ear. “Summer is the peak season for swimmer’s ear, which is an inflammation of the skin of the ear canal,” said Eric Smouha, MD, Associate Professor of Otolaryngology at the Icahn School of Medicine at Mount Sinai. “Basically, it’s caused by water in the ear canal, because where there’s entrapped water, there’s inevitably bacteria, which can cause an incredibly painful infection because there’s not much room to accommodate the swelling.” Some 2.4 million cases of swimmer’s ear were diagnosed in this country in 2007 alone. -Dr. Eric Smouha, Associate Professor, Otolaryngology, Director, Otology and Neurology, Icahn School of Medicine at Mount Sinai Learn more: http://www.nydailynews.com/life-style/health/daily-checkup-summer-time-rise-swimmer- ear-article-1.1849595

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: MountSinaiNewsNow Subject: Mount Sinai In The News - July 3, 2014 Date: Thursday, July 03, 2014 12:40:14 PM

In the News July 3, 2014

Forbes – July 2 Drive-Thru Health Care: How McDonald's Inspired an Urgent Care Gold Rush The key is that the 10,000 urgent care clinics across the country, handling 160 million visits annually, are an appealing medical model wrapped up in a proven consumer-driven business plan. Kenneth Davis, MD, CEO and President of the Mount Sinai Health System, wants the Mount Sinai Health System’s clinics to act as feeders into his system’s broader network of services. “We need patients to get connected in some way that provides follow-up and continuity of care, rather than just episodic,” said Dr. Davis. “[Urgent care] is no way to prevent disease or maximize outcomes.” -Dr. Kenneth L. Davis, CEO and President, Mount Sinai Health System Learn more: http://www.forbes.com/sites/briansolomon/2014/07/02/drive-thru-health-care-how- mcdonalds-inspired-an-urgent-care-gold-rush/

Forbes – July 2 Why Thousands of Men Like JPMorgan CEO Jamie Dimon Are Getting Throat Cancer – Matthew Herper Last night, Jamie Dimon, the chief executive of banking giant JPMorgan, told employees that he is being treated for throat cancer. It’s very possible that Dimon has been swept up, along with thousands of other men, by an increasingly common disease: throat cancer caused by infection with the human papilloma virus, or HPV. “It wouldn’t be unusual,” said Eric Genden, MD, Professor and Chief of Otolaryngology/Head and Neck Surgery, and Immunobiology, and Chief of the Division of Head and Neck Oncology at The Mount Sinai Hospital. -Dr. Eric Genden, Professor and Chair, Otolaryngology/Head and Neck Surgery, Immunobiology, Chief, Division, Head and Neck Oncology, The Mount Sinai Hospital Learn more: http://www.forbes.com/sites/matthewherper/2014/07/02/why-thousands-of-men-like-j-p- morgan-ceo-jamie-dimon-are-getting-throat-cancer/

Medscape Multispecialty – July 2 Dr. Fuster Takes the Reins at JACC – Tricia Ward Valentin Fuster, MD, PhD, who describes the findings as "extraordinary," is Director of Mount Sinai Heart, the Zena and Michael A. Wiener Cardiovascular Institute and the Marie-Josée and Henry R. Kravis Center for Cardiovascular Health at The Mount Sinai Hospital, is the new Editor-in-Chief of the Journal of the American College of Cardiology (JACC), and the July 8 issue marks the first under his regime. “I'd like to give the young people the same chance to express themselves in the journal that I have as editor, or that the ACC leaders have,” said Dr. Fuster. “And every four weeks there will be an international page by a world-recognized expert so that we can have crossover and learn what is going on in different venues.” -Dr. Valentin Fuster, Director of Mount Sinai Heart, the Zena and Michael A. Wiener Cardiovascular Institute and the Marie-Josée and Henry R. Kravis Center for Cardiovascular Health, The Mount Sinai Hospital Learn more: http://www.medscape.com/viewarticle/827642

Ekathimerini – July 3 Through the prism of Greeks and Greek-Americans with interesting work lives, the ‘Greeks Gone West’ segment from Ekathimerini aims to improve the understanding of U.S. society and to show possibilities during a time, in Greece, when life seems full of limitations and frustrations. “Truth is, I’ve always had interested in the gay, lesbian, bisexual, transgender community from the perspective of health,” said Demetre Daskalakis, MD, Senior Faculty of Medicine, and Infectious Diseases, and Medical Director of Ambulatory HIV Services at The Mount Sinai Hospital. “It all worked out in the direction that the community that I was the most interested in also became the center of my career. The goal is to get the level of HIV cases down below epidemic levels in New York in the next few years.” -Dr. Demetre Daskalakis, Senior Faculty, Medicine, Infectious Diseases, Medical Director, Ambulatory HIV Services, The Mount Sinai Hospital Learn more: http://www.ekathimerini.com/4dcgi/_w_articles_wsite6_1_03/07/2014_541071

Queens Gazette – July 2 Mount Sinai Queens Honors Physicians for Dedication More than 60 physicians were honored at Mount Sinai Queens Annual Physician Longevity Awards on June 17. “Physicians do so much for our community and for our hospital that often goes unacknowledged,” said Brian Radbill, MD, FACP, Chief Medical Officer and Vice President of Medical Affairs at Mount Sinai Queens and emcee for the celebration. Caryn A. Schwab, Executive Director of Mount Sinai Queens presented an award to Roberto C. Granato for 50 years of service, beginning in 1964. “This year we lose our very elegant physician to retirement. We wish him well on his next journey,” said Schwab. -Dr. Brian Radbill, Chief Medical Officer, Vice President, Medical Affairs, Mount Sinai Queens -Caryn A. Schwab, Executive Director, Mount Sinai Queens Learn more: http://www.qgazette.com/news/2014-07- 02/Features/Mount_Sinai_Queens_Honors_Physicians_For_Dedicatio.html

Healthline – July 2 Gene Marker Predicts Celiac Disease Risk in Young Children – Kristen Fischer A new study finds that more than one quarter of children with two copies of a high-risk gene variant develop celiac disease autoimmunity (CDA) by the age of five. CDA is a precursor to celiac disease. Nearly 90 percent of people with full-blown celiac disease have at least one copy of this high-risk gene. "I think further studies on the environmental risk factors will give us more information on how to prevent celiac disease in the patients who have an increased genetic risk," said Gina Sam, MD, Assistant Professor of Medicine and Gastroenterology at The Mount Sinai Hospital. -Dr. Gina Sam, Assistant Professor, Medicine, Gastroenterology, The Mount Sinai Hospital Learn more: http://www.healthline.com/health-news/gene-predicts-celiac-risk-070214

WCBS TV – July 1 Is Smoke from a Charcoal Grill Dangerous? While effects of second-hand cigarette smoke have been studied extensively and deemed dangerous, less is known about the impact of charcoal smoke. Still, the anti-grill movement is being bolstered by medical data which shows charcoal smoke includes coal dust, lime stone and borax. Robert Foronjy, MD, Department of Pulmonary Medicine and Critical Care, Mount Sinai St. Luke’s and Mount Sinai Roosevelt, said, “When you burn anything you’re releasing particles, those particles when they are breathed into the lung are irritants and they can cause broncho-spasms, cough and over the long-term they can cause diseases like emphysema and chronic bronchitis.” -Dr. Robert Foronjy, Department of Pulmonary Medicine and Critical Care, Mount Sinai St. Luke’s and Mount Sinai Roosevelt Learn more: http://newyork.cbslocal.com/2014/07/01/brooklyn-resident-calls-for-end-to-charcoal- grilling-in-prospect-park/

Medscape Multispecialty – July 2 Insulin-Pump Therapy Benefits Some with Type 2 Diabetes – Miriam E. Tucker Insulin-pump treatment can be effective for patients with type 2 diabetes in whom multiple daily injections do not provide adequate glycemic control, a new study finds. Zachary T. Bloomgarden, Clinical Professor of Medicine, Endocrinology, Diabetes and Bone Disease at the Icahn School of Medicine at Mount Sinai, said, "It is an interesting study of a very specific and clinically very important subset of patients with diabetes, those who are not able to achieve good glycemic control despite treatment including multiple doses of insulin.” -Dr. Zachary T. Bloomgarden, Clinical Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: http://www.medscape.com/viewarticle/827748

Health – July 2 What You Need to Know About Pelvic Exams – Amanda Gardner The ACP says that some parts of the pelvic exam (palpitating the ovaries, for example), aren’t all that helpful, rarely detecting important diseases or saving lives, and that they’re uncomfortable and cost extra. “I feel that [the ACP guidelines] are based on limited data and that annual pelvic exams do offer benefits so they shouldn’t be discontinued as routine exams,” said Taraneh Shirazian, MD, Director of Global Women’s Health and Assistant Professor of Obstetrics, Gynecology and Reproductive Science at The Mount Sinai Hospital. -Dr. Taraneh Shirazian, Director, Global Women’s Health, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, The Mount Sinai Hospital Learn more: http://news.health.com/2014/07/02/what-you-need-to-know-about-pelvic-exams/

Allure – July 1 The Top 14 Summer Beauty Buzzkills: Solved – Ramona Emerson For those who went outside on your lunch break, and are now hot and have a red face, “Reduce the flush by sucking on an ice cube or holding a cold water bottle against your neck. This stimulates a receptor at the back of the throat to constrict the blood vessels in the face,” said Joshua Zeichner, MD, Assistant Professor of Dermatology and Director of Cosmetic and Clinical Research at The Mount Sinai Hospital. -Dr. Joshua Zeichner, Assistant Professor, Dermatology, Director, Cosmetic and Clinical Research, The Mount Sinai Hospital Learn more: http://www.allure.com/beauty-trends/how-to/2014/summer-beauty-problems-solutions

KFOR (Oklahoma City) – July 2 Trending Story: You’d be Surprised by Some of the Strange Things Doctors Hear Inspired by a topic on Reddit, CNN reached out to health care providers, seeking stories of patients armed with surprising medical misinformation. “Many people think fiber cures constipation,” said Neville Bamji, MD, a Clinical Instructor of Medicine and Gastroenterology at The Mount Sinai Hospital. “It can help with minor constipation, but it isn’t meant to be a cure.” -Dr. Neville Bamji, Clinical Instructor, Medicine, Gastroenterology, The Mount Sinai Hospital Learn more: http://kfor.com/2014/07/02/trending-story-youd-be-surprised-by-some-of-the-strange- things-doctors-hear-we-certainly-were/

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: MountSinaiNewsNow Subject: Mount Sinai In The News - July 2, 2014 Date: Wednesday, July 02, 2014 2:54:12 PM

In the News July 2, 2014

Futurity.com – July 1 Herpes Blamed for Rise in HIV among Some Drug Users HIV infection among heterosexual people who take drugs without injecting them has doubled during the last two decades in New York City, and researchers say herpes may be behind the increase. “Heterosexual intercourse is usually not very efficient for transmitting HIV, but the efficiency of heterosexual transmission nearly triples in the presence of herpes simplex virus type 2,” said the study’s lead author, Don Des Jarlais, PhD, Professor of Psychiatry and Preventive Medicine at Mount Sinai Beth Israel. The study was funded by The National Institutes of Health, and appears in the journal PLOS ONE. -Dr. Don Des Jarlais, Director, Research, Baron Edmond de Rothschild Chemical Dependency Institute, Mount Sinai Beth Israel Learn more: http://www.futurity.org/herpes-hiv-drug-users-725512/

The Washington Post – July 1 Pelvic Exams No Longer Recommended For Well-Woman Visits – Jenny Gold The American College of Physicians announced a major change to their screening guidelines Monday evening: Healthy women should no longer receive pelvic exams during their annual well-woman visits. “Honestly, it concerns me,” said Taraneh Shirazian, MD, Director of Global Women’s Health and Assistant Professor of Obstetrics, Gynecology and Reproductive Science at The Mount Sinai Hospital. “We’ve had changes to the mammogram recommendations, the Pap smear, and now the pelvic exam. All of it means that women may opt not to visit their gynecologist as often.” -Dr. Taraneh Shirazian, Director, Global Women’s Health, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, The Mount Sinai Hospital Learn more: http://www.washingtonpost.com/national/health-science/pelvic-exams-no-longer- recommended-for-well-woman-visits/2014/07/01/5175ae8e-0124-11e4-9a6a-955ebcaa3334_story.html Additional coverage: The Today Show: http://www.today.com/klgandhoda/new-pelvic-exam-guidelines-what-you-need- know-1D79871721 CBS This Morning: http://www.cbsnews.com/videos/medical-group-says-most-women-can-skip-pelvic- exams/

Prevention – July 1 Should You Skip Your Yearly Pelvic Exam? – Alexandra Sifferlin A pelvic exam for women who are not pregnant and do not have symptoms of cancer may be unnecessary, says the American College of Physicians (ACP) in a controversial new set of guidelines published Monday in the Annals of Internal Medicine. The ACP, which reviewed studies on the harms and benefits of pelvic exams, said the procedure does not detect disease as well as previously thought; it doesn’t reduce mortality; and it leads to many false positives, resulting in unnecessary testing and anxiety. “I think in the obstetrics and gynecology world, everyone will laugh at this and think this is the silliest thing they have ever heard,” said David Fishman, MD, Director of the National Ovarian Cancer Early Detection Program, and Professor of Obstetrics, Gynecology and Reproductive Medicine at The Mount Sinai Hospital. -Dr. David Fishman, Director, National Ovarian Cancer Early Detection Program, Professor, Obstetrics, Gynecology and Reproductive Medicine, The Mount Sinai Hospital Learn more: http://www.prevention.com/health/health-concerns/new-recommendation-annual-pelvic- exams

WCBS TV – July 1 Dr. Max Gomez: Summer Kidney Stones Regarding things people worry about during the summer months, kidney stones are near the bottom of the list. “Part of that has to do with dehydration,” said Mantu Gupta, MD, Director of the Kidney Stone Center of Mount Sinai, and Chair of Urology at Mount Sinai St. Luke’s and Mount Sinai Roosevelt. “Urine becomes more concentrated, and when urine is more concentrated, the more likely crystals will form and join together to form kidney stones.” -Dr. Mantu Gupta, Director, Kidney Stone Center of Mount Sinai, Chair, Urology, Mount Sinai St. Luke's, Mount Sinai Roosevelt Learn more: http://newyork.cbslocal.com/video/10322331-dr-max-gomez-summer-kidney-stones/

MedPage Today – July 1 Pelvic Exams: Comments from Clinicians – Charles Bankhead In a new clinical guideline released Monday, the American College of Physicians recommended against routine pelvic exams for average-risk, asymptomatic women. “It hasn’t been proven to be of any benefit,” said Aida Vega, MD, Director of the Mount Sinai Doctors Faculty Practice Associates of The Mount Sinai Hospital. “We would like to schedule appointments with women, just to discuss other important areas in their health, such as smoking, cessation, blood pressure monitoring, body-mass index (BMI), or weight.” -Dr. Aida Vega, Director, Mount Sinai Doctors Faculty Practice Associates, The Mount Sinai Hospital Learn more: http://www.medpagetoday.com/OBGYN/GeneralOBGYN/46568

MedPage Today – July 1 Bone Marrow Tx Promising in Adult Sickle Cell – Crystal Phend Bone marrow transplantation with reduced intensity, nonmyeloablative conditioning cured many adults with severe sickle cell disease, updated results from a pilot study affirmed. "It still works as a cure, because the patient only needs to make a little bit of donor blood to be functionally cured," said Jeffrey Glassberg, MD, Director of Sickle Cell Disease Research, and Assistant Professor of Medicine, Emergency Medicine, Hematology and Medical Oncology at The Mount Sinai Hospital. -Dr. Jeffrey Glassberg, Director, Sickle Cell Disease Research, Assistant Professor, Medicine, Emergency Medicine, Hematology and Medical Oncology, The Mount Sinai Hospital Learn more: http://www.medpagetoday.com/HematologyOncology/Hematology/46580

Healthline – July 1 One Third of Knee Replacements for Arthritis May Be Unnecessary – Kristen Fischer A new study calls for better and more modern ways to evaluate patients before total knee replacement surgery. Under current guidelines, many patients may be receiving the procedure when it could be avoided. “Regardless of the instrument used, it is intuitive that if the patient answers ‘none or mild’ on all items relating to pain and function, the surgeon should re-evaluate his indication for surgery,” said Steven Harwin, MD, Chief of Adult Reconstruction and Total Joint Replacement at Mount Sinai Beth Israel. “In my practice, the typical patient indicated for joint replacement of either the hip or knee has an average pain score of over seven out of 10, and 90 percent have functional limitations that include walking, standing, and bending.” -Dr. Steven Harwin, Chief, Adult Reconstruction and Total Joint Replacement, Mount Sinai Beth Israel Learn more: http://www.healthline.com/health-news/one-third-knee-replacements-unnecessary-070114

Business to Community – July 2 Big Data: A New Type of Marketing ROI – Dan Newman The powerful trend of Big Data further laments itself into community building efforts as industries like Higher Education and Health Care embrace its powers to wield more tailored environments for students and patients. One great example of this is how The Mount Sinai Hospital is using Big Data to predict disease, reduce patient visits and improve the keeping of electronic medical records. The improved patient experience will likely contribute to more loyalty among patients and improved recognition of the hospital for their innovative approach to healthcare. -The Mount Sinai Hospital Learn more: http://www.business2community.com/big-data/big-data-new-type-marketing-roi- 0932871#!7gF7H

HealthDay – July 2 Glaucoma Can Affect Babies, Too – Amy Norton When Olivia Goree noticed something just "wasn't right" about her six-week-old son's eyes, she trusted her instincts and took him to the doctor. What she never expected was the diagnosis: glaucoma. "The cornea gets so big, there can end up being 'breaks' in the back of the cornea," said Tamiesha Frempong, MD, Assistant Professor of Ophthalmology at The Mount Sinai Hospital. “The cornea is the normally clear outer layer of the eye. In an infant with congenital glaucoma, it starts to take on a hazy appearance.” -Dr. Tamiesha Frempong, Assistant Professor, Ophthalmology, The Mount Sinai Hospital Learn more: http://consumer.healthday.com/senior-citizen-information-31/glaucoma-news-335/vision- robbing-glaucoma-can-affect-babies-too-689243.html

Psych Central – July 1 Alcohol Disorders More Likely to Push Women Off Career Ladder – Rick Nauert A new study reviewed the relationship between occupation and alcohol use disorders (AUDs) in workers during early adulthood to middle age, and the news for women in particular should give pause. The study suggests that declining occupational trajectory is a consequence of AUD development, rather than a predictor. However, the link between AUDs and occupation appears to be “complex and reinforcing,” said John D. Meyer, MD, MPH, Senior Faculty of Preventive Medicine at the Icahn School of Medicine at Mount Sinai. -Dr. John D. Meyer, Senior Faculty, Preventive Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://psychcentral.com/news/2014/07/02/alcohol-disorders-more-likely-to-push-women- off-career-ladder/71992.html

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: MountSinaiNewsNow Subject: Mount Sinai In The News - July 1, 2014 Date: Tuesday, July 01, 2014 1:46:11 PM

In the News July 1, 2014

The Daily Beast – July 1 The Genetic Heroes That Could Cure the Sick – Carrie Arnold One person in 20,000 is predicted to be a ‘genetic hero’—someone who should have a disease, but due to rare mutations or lifestyle, doesn’t. Now, the Resilience Project is making it easier than ever to find them, and hopefully find treatment for the sick in the process. Scientists Stephen Friend of Sage Biosciences and Eric Schadt, PhD, Director of the Institute for Genomics and Multiscale Biology, Chairman of the Department of Genetics and Genomics Sciences, and the Jean C. and James W. Crystal Professor of Genomics at the Icahn School of Medicine at Mount Sinai, and Co-Investigator of the Resilience Project, described their new endeavor called the Resilience Project last month in the journal Science, which seeks to find individuals carrying genes that should normally lead to severe disease but have no signs of illness. “The human genetics community is focused on disease. We want to turn it around and identify people who should be sick but aren’t,” said Dr. Schadt. “However they manage to resist disease could yield new treatments.” -Dr. Eric Schadt, Director of the Institute for Genomics and Multiscale Biology, Chairman of the Department of Genetics and Genomics Sciences and the Jean C. and James W. Crystal Professor of Genomics, Icahn School of Medicine at Mount Sinai Learn more: http://www.thedailybeast.com/articles/2014/07/01/the-genetic-heroes-that-could-cure-the- sick.html

The Wall Street Journal – June 30 Routine Pelvic Exam Isn't Helpful, Report Says – Angela Chen Healthy women don't need regular pelvic exams, says the American College of Physicians, in a new set of guidelines released Monday. The guidelines were published in the Annals of Internal Medicine. The physicians group represents internists, who specialize in diagnosing and treating adult diseases. "This recommendation, in my mind, would unfortunately compromise women's health care by suggesting that a thorough gynecologic exam is not required,” said David Fishman, MD, Director of the National Ovarian Cancer Early Detection Program, and Professor of Obstetrics, Gynecology and Reproductive Medicine at The Mount Sinai Hospital. "The exam may not be 100 percent sensitive, and it may not be able to pick up cancer of the ovary, but it gives us a baseline idea of health and is one piece of what we can easily offer women that can help with education and counseling," said Taraneh Shirazian, MD, Director of Global Women’s Health and Assistant Professor of Obstetrics, Gynecology and Reproductive Science at The Mount Sinai Hospital. -Dr. David Fishman, Director, National Ovarian Cancer Early Detection Program, Professor, Obstetrics, Gynecology and Reproductive Medicine, The Mount Sinai Hospital -Dr. Taraneh Shirazian, Director, Global Women’s Health, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, The Mount Sinai Hospital Learn more: http://online.wsj.com/articles/regular-pelvic-exam-isnt-helpful-report-says-1404163414 New York Daily News: http://www.nydailynews.com/life-style/health/doctor-group-urges- gynecological-pelvic-exams-article-1.1849891

CBS News – June 30 Doctors' Group Says Annual Pelvic Exams Unnecessary for Healthy Women – Jessica Firger The American College of Physicians (ACP) is challenging the need for annual pelvic exams. On Monday the group published a new set of guidelines that recommends against annual pelvic exams for healthy, non-pregnant women. The systematic review and recommended physician guidelines were published today in Annals of Internal Medicine. "For me, I'm a gynecologist so I've examined thousands of women. I've picked up very early findings in my patients, early fibroids, early cysts. Some of the patients were asymptomatic, some of the patients did have symptoms but didn't realize that those symptoms were linked with their uterus or ovaries,” said Taraneh Shirazian, MD, Director of Global Women’s Health and Assistant Professor of Obstetrics, Gynecology and Reproductive Science at The Mount Sinai Hospital. -Dr. Taraneh Shirazian, Director, Global Women’s Health, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, The Mount Sinai Hospital Learn more: http://www.cbsnews.com/news/doctors-group-says-annual-pelvic-exams-unnecessary-for- healthy-women/ Additional coverage: NBC News: http://www.nbcnews.com/id/55547781 CBS 2 New York: http://newyork.cbslocal.com/2014/06/30/dr-max-gomez-medical-group-issues-new- guidance-on-pelvic-exams/ USA Today: http://www.usatoday.com/story/news/nation/2014/06/30/pelvic-exam- recommendation/11783369/ Shape: http://www.shape.com/blogs/shape-your-life/regular-pelvic-exams-not-necessary-all-women- group-says WTHR (Indiana): http://www.wthr.com/story/25908285/2014/06/30/new-study-recommends-against- annual-pelvic-exams-for-women Local 8 (Tennessee): http://www.local8now.com/home/headlines/Pelvic-exams-might-be-265307121.html The Week: http://theweek.com/speedreads/index/264038/speedreads-doctors-group-says-healthy- women-dont-need-regular-pelvic-exams The Guardian Liberty Voice: http://guardianlv.com/2014/06/new-recommendations-state-most-women- do-not-need-yearly-pelvic-exams/ WKRZ (Cincinnati): http://www.local12.com/news/features/top-stories/stories/american-college- physicians-says-most-women-dont-need-pelvic-exams-13845.shtml

Time – June 30 Skip the Pelvic Exam, Says the American College of Physicians – Alexandra Sifferlin A pelvic exam for women who are not pregnant and do not have symptoms of cancer may be unnecessary, says the American College of Physicians (ACP) in a controversial new set of guidelines published Monday in the Annals of Internal Medicine. But their guidelines are not being met with widespread praise. “I think in the obstetrics and gynecology world, everyone will laugh at this and think this is the silliest thing they have ever heard,” said David Fishman, MD, Director of the National Ovarian Cancer Early Detection Program, and Professor of Obstetrics, Gynecology and Reproductive Medicine at The Mount Sinai Hospital. -Dr. David Fishman, Director, National Ovarian Cancer Early Detection Program, Professor, Obstetrics, Gynecology and Reproductive Medicine, The Mount Sinai Hospital Learn more: http://time.com/2941289/skip-the-pelvic-exam-says-the-american-college-of-physicians/ Additional coverage: Utah People’s Post: http://www.utahpeoplespost.com/2014/07/routine-pelvic-exams/ Healthline: http://www.healthline.com/health-news/fewer-pelvic-exams-necessary-acp-063014 ModVive: http://www.modvive.com/2014/06/30/yearly-pelvic-exams-harm-good-study-says/

Yahoo! (from Agence France-Presse) – June 30 Pelvic Exam not Needed for All Women: US Doctors' Group – Kerry Sheridan A manual pelvic examination in which gynecologists use their hands to feel around for potentially cancerous masses is not needed for most women, the American College of Physicians (ACP) said Monday. "It is an important study to question what we do. It is not enough data in my view to completely change your practice," said Laura MacIsaac, MD, Associate Professor of Obstetrics, Gynecology and Reproductive Science at the Icahn School of Medicine at Mount Sinai. The systematic review and recommended physician guidelines were published today in Annals of Internal Medicine. -Dr. Laura MacIsaac, Associate Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://news.yahoo.com/pelvic-exam-not-needed-women-us-doctors-group-214342665.html Additional coverage: Yahoo! (United Kingdom): https://uk.news.yahoo.com/pelvic-exam-not-needed-women-us-doctors- group-204342190.html Times Live (Johannesburg): http://www.timeslive.co.za/lifestyle/2014/07/01/risks-outweigh-benefits-of- pelvic-exam-for-women-say-doctors-group News Daily: http://www.newsdaily.com/article/81d218381a665f8e61a543d87b598c17/pelvic-exam-not- needed-for-all-women-us-doctors-group

Becker’s Hospital Review – June 30 50 Top-Grossing Nonprofit Hospitals | 2014 – Heather Punke Becker’s Hospital Review listed the 50 top-grossing nonprofit hospitals in the United States for 2014 based on gross revenue, according to CMS cost report data analyzed by American Hospital Directory. Data are for short term acute-care hospitals, critical access hospitals and children's hospitals. The Mount Sinai Hospital was included on the list. -The Mount Sinai Hospital Learn more: http://www.beckershospitalreview.com/lists/50-top-grossing-nonprofit-hospitals-2014.html

MedPage Today – June 30 CardioBreak: Sex and Heart Problems, World Cup Heart Attack – Todd Neale Mount Sinai Heart has created a Center for Medical Devices, which has the goal "to advance the field of cardiovascular medicine and accelerate the delivery of promising medical devices to cardiac patients." Mount Sinai also announced publication of a free downloadable issue of Scientific American focused on promoting cardiovascular health worldwide. -The Mount Sinai Hospital Learn more: http://www.medpagetoday.com/Cardiology/Prevention/46558

Laboratory Design – May 20 Mount Sinai Hess Center for Science and Medicine Conceived as a place of discovery and healing, Mount Sinai’s Hess Center is a translational research building shaped by its dual mission and thematically linked program. The 420,000-square-foot building unites scientists, clinicians and educators, fostering interaction and multidisciplinary collaboration. -The Mount Sinai Hospital Learn more: http://www.labdesignnews.com/news/2014/05/mount-sinai-hess-center-science-and- medicine

TCTMD – June 30 Some Long-term Drop-Off in Favorable Outcomes Seen in Early CoreValve Series In high-surgical-risk patients with severe aortic stenosis who survived to 3 years after transcatheter aortic valve replacement (TAVR) with the CoreValve prosthesis, improvements in hemodynamics and symptoms were largely maintained, according to a study to be published in the American Journal of Cardiology. Compared with the U.S. CoreValve Pivotal trial, for which David Adams, MD, Professor and Chair of Cardiothoracic Surgery at The Mount Sinai Hospital, was co-principal investigator, "there were many more patients who had residual aortic insufficiency," he said. "[The current study also] had many more patients that were [NYHA] class III and IV after TAVR.” -Dr. David Adams, Professor, Chair, Cardiothoracic Surgery, The Mount Sinai Hospital Learn more: http://www.tctmd.com/show.aspx?id=124724

Refinery 29 – June 30 FDA Issues Health Warning for Anti-Acne Products – Kristin Booker The U.S. Food and Drug Administration recently issued a warning that “certain over-the-counter (OTC) topical acne products can cause rare but serious and potentially life-threatening allergic reactions or severe irritation,” which are described as “hypersensitivity reactions such as throat tightness; difficulty breathing; feeling faint; or swelling of the eyes, face, lips, or tongue” as well as any development of hives and/or itching. “If you look at the data, the range of ages of those reporting reactions was 11 to 78, which is a big range of patients. You have to think about how you use the products at different ages,” said Jeanette Graf, MD, Assistant Clinical Professor of Dermatology at the Icahn School of Medicine at Mount Sinai. -Dr. Jeannette Graf, Assistant Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://www.refinery29.com/2014/06/70456/fda-acne-products-allergic-warning

Daily Digest News – June 30 Potential Substitute for Wheelchairs Gains FDA Approval – Vinitra Nathan The U.S. Food and Drug Administration recently approved the home use of the ReWalk robot exoskeleton. The device acts as a “wearable robot”, by assisting paraplegics to walk upright and be mobile. According to Allan Kozlowski, PhD, Assistant Professor of Rehabilitation Medicine at the Icahn School of Medicine at Mount Sinai, and head of the Exoskeleton-Assisted Walking Program at The Mount Sinai Hospital, patients using ReWalk experience better circulation, increased oxygen intake, pain relief, improved bowel function, and increased psychological benefits that come from being able to stand upright and look people in the eye. -Dr. Allan Kozlowski, Assistant Professor, Rehabilitation Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://dailydigestnews.com/2014/06/potential-substitute-for-wheelchairs-gains-fda- approval/

Western Queens Gazette – July 2014 Long Island City Summit Holds First Ever Gathering The first Long Island City Summit opened at the Museum of the Moving Image last week on Tuesday morning. At the summit, Caryn Schwab, Executive Director of Mount Sinai Queens in Astoria said that hospitals are now less a matter of beds than outpatient care and that MSQ’s new, six-story facility was built for the necessities of the 21st century, which include expanding the primary care base. -Caryn A. Schwab, Executive Director, Mount Sinai Queens Learn more: http://www.qgazette.com/news/2014-07- 02/Features/Long_Island_City_Summit_Holds_First_Ever_Gathering.html

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