IFMBE Proceedings

Volume 46

Series Editor Ratko Magjarevic

Deputy Editors Fatimah Binti Ibrahim Igor Lackovic´ Piotr Ładyzy˙ nski´ Emilio Sacristan Rock The International Federation for Medical and Biological Engineering, IFMBE, is a federation of national and transnational organizations representing internationally the interests of medical and biological engineering and sciences. The IFMBE is a non-profit organization fostering the creation, dissemination and application of medical and biological engineering knowledge and the management of technology for improved health and quality of life. Its activities include participation in the formulation of public policy and the dissemination of information through publications and forums. Within the field of medical, clinical, and biological engineering, IFMBE’s aims are to encourage research and the application of knowledge, and to disseminate information and promote collaboration. The objectives of the IFMBE are scientific, technological, literary, and educational.

The IFMBE is a WHO accredited NGO covering the full range of biomedical and clinical engineering, healthcare, healthcare technology and management. It is representing through its 60 member societies some 120.000 professionals involved in the various issues of improved health and health care delivery.

IFMBE Officers President: Ratko Magjarevic, Vice-President: James Goh Past-President: Herbert Voigt Treasurer: Marc Nyssen, Secretary-General: Shankhar M. Krishnan http://www.ifmbe.org

More information about this series at http://www.springer.com/series/7403 Vo Van Toi · Tran Ha Lien Phuong Editors

5th International Conference on Biomedical Engineering in Vietnam

ABC Editors Vo Va n Toi Tran Ha Lien Phuong Biomedical Engineering Department Biomedical Engineering Department International University International University Vietnam National Universities Vietnam National Universities Ho Chi Minh City Ho Chi Minh City Vietnam Vietnam

ISSN 1680-0737 ISSN 1433-9277 (electronic) ISBN 978-3-319-11775-1 ISBN 978-3-319-11776-8 (eBook) DOI 10.1007/978-3-319-11776-8

Library of Congress Control Number: 2014954484

Springer Cham Heidelberg New York Dordrecht London

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The IFMBE Proceedings is an Official Publication of the International Federation for Medical and Biological Engineering (IFMBE)

Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com) Preface

Welcome to the Fifth International Conference on the Development of Biomedical Engineering in Vietnam.

Vietnam is a rapidly developing, socially dynamic country, where interest in biomedical engineering activities has grown con- siderably in recent years. The leadership of the Vietnamese government, and of research and educational institutions, are well aware of the importance of this field for the development of the country and have instituted policies to promote its development. The political, economic and social environment within the country offers unique opportunities for the international community and this conference was intended to provide a vehicle for the sharing of experiences; development of support and collaboration networks for research; and exchange of ideas on how to improve the educational and entrepreneurial environment to better address the urgent needs of Vietnam. In January 2004, under the sponsorship of the U.S. National Science Foundation, Professor Vo Van Toi of the Biomedical Engineering Department of Tufts University, Medford Massachusetts USA, led a U.S. delegation that consisted of Biomedical Engineering professors from different universities in the United States, and visited several universities and research institutions in Vietnam to assess the state of development of this field. This delegation proposed a five year plan that was enthusiastically embraced by the international scientific communities to actively develop collaborations with Vietnam. Within this framework, in July 2005, the First International Conference on the Development of Biomedical Engineering in Vietnam was held in Ho Chi Minh City. From that conference a Consortium of Vietnam- International Universities was created to advise and assist the development of Biomedical Engineering in Vietnamese universities. In July 2007, the Second International Conference on the Development of Biomedical Engineering in Vietnam was held in Hanoi. During this event the Vietnamese Association of Biomedical Science and Engineering was endorsed by the Asia- Pacific International Molecular Biology Network (AIMBN), Biomedical Engineering Society Singapore (BESS), International Federation for Medical and Biological Engineering (IFMBE), Société Française de Génie Biologique et Médical (SFGBM) and IFMBE Asia-Pacific Working Group. In March 2009, International University (IU) established its Biomedical Engineering (BME) Department and the first accredited Engineer in BME degree in Vietnam (code: 52.42.02.04). IU is a member of Vietnam National Universities – Ho Chi Minh City (VNU-HCM), one of the two elite university networks in Vietnam, and is the first public university in Vietnam that teaches all courses in English. It was created as a new model to modernize the higher education in Vietnam. The BME Department at IU has since coordinated with its national and international counterparts to promote the activities of this field in Vietnam. In January 2010, the Third International Conference on the Development of Biomedical Engineering in Vietnam was organized by IU in Ho Chi Minh City. It reflected the steady growth of the activities in this field in Vietnam, and featured the contributions of researchers of 21 countries, including: Australia, Belgium, Canada, Denmark, France, India, Japan, Korea, Malaysia, New Zealand, Philippines, Poland, Russia, Singapore, Spain, Switzerland, Taiwan, Thailand, United Kingdom, the United States and Vietnam. The Conference was endorsed by the International Federation for Medical and Biological Engineer- ing (IFMBE). It also hosted the Clinical Engineering Workshop of the IFMBE Asia Pacific Working Group. The contributed papers were published in the IFMBE Proceedings Series by Springer (ISBN 978-3-642-12019-0). In January 2012, the Fourth International Conference on the Development of Biomedical Engineering in Vietnam was organized in Ho Chi Minh City as a Mega-conference. It was kicked off by the Regenerative Medicine Conference (Jan 8-10, 2012) with the theme “BUILDING A FACE” USING A REGENERATIVE MEDICINE APPROACH”, endorsed mainly by the Tissue Engineering and Regenerative Medicine International Society (TERMIS) and co-organized by Professor Stephen E. Feinberg, University of Michigan Health System, USA, Professor Anh Le, University of Southern California, USA and Professor Vo Van Toi, International University-VNU HCM, Vietnam. It was followed by the Computational Medicine Con- ference, endorsed mainly by the Computational Surgery International Network (COSINE) and the Computational Molecular Medicine of German National Funding Agency; and the General Biomedical Engineering Conference, endorsed mainly by the International Federation for Medical and Biological Engineering (IFMBE) (Jan 10-12) and co-organized by Professor Paolo Carloni, German Research School for Simulation Sciences GmbH, Germany, Professor Marc Garbey, University of Houston, VI Preface

USA and Professor Vo Van Toi, International University-VNU HCM, Vietnam. It featured the contributions of 435 scientists from 30 countries, including: Australia, Austria, Belgium, Canada, China, Finland, France, Germany, Hungary, India, Iran, Italy, Japan, Jordan, Korea, Malaysia, Netherlands, Pakistan, Poland, Russian Federation, Singapore, Spain, Switzerland, Tai- wan, Turkey, Ukraine, United Kingdom, United States, Uruguay and Viet Nam. The contributed papers were published in the IFMBE Proceedings Series by Springer (ISBN 978-3-642-32182-5). This Fifth International Conference on the Development of Biomedical Engineering in Vietnam (June 16-18, 2014) is a very special event. It officially opens the season for celebration of the 20th Anniversary of Vietnam National Universities – Ho Chi Minh City. It also marks the 10th Anniversary of International University and the 5th Anniversary of the Biomedical Engineering Department. This Conference features 199 papers of 508 authors and co-authors from 26 countries including Aus- tralia, Bangladesh, Belgium, Canada, China, Croatia, Czech Republic, Denmark, Finland, France, Germany, India, Israel, Italy, Japan, Korea, Malaysia, Norway, Singapore, Slovenia, Switzerland, Taiwan, Turkey, United Kingdom, USA and Vietnam. Al- most all Vietnamese institutions have their delegations. Besides Vietnam the 2 countries that have the most contributors are the USA and Australia. The plenary session features the lectures on the progress in different fields of Biomedical Engineering by distinguished keynote speakers such as Prof. Ratko Magjarevic, President of IFMBE; Dr. Robert A. Lieberman, Vice-President of International Society for Optics and Photonics SPIE; Prof. Vo-Dinh Tuan, Director of Fitzpatrick Institute for Photonics, Duke University, USA; Prof. Christian Griesinger, Director of Max Planck Institute for Biophysical Chemistry, Germany; Prof. Anja Boisen, Director of VKR Centre Of Excellence ‘NAMEC’, Denmark; Prof. Yin Xiao, Director of Australia-China Centre for Tissue Engineering and Regenerative Medicine, Queensland University of Technology, Australia; Prof. Yukio Nagasaki, Department of Materials Science and Medical Sciences, University of Tsukuba, Japan; and Prof. Fong-Chin Su, President of Taiwanese Society of Biomedical Engineering, Director, Medical Device Innovation Center, National Cheng Kung University, Taiwan. The contributed papers will continue to be published in the IFMBE Proceedings Series by Springer. The editors would like to thank the leadership and staff of VNU-HCM and IU, local and international sponsors, and the staff and students of Biomedical Engineering Department for their valuable support for the conference and their assistance in the editing and publication of the volume.

Editors Vo Va n To i Tran Ha Lien Phuong and Editorial Board Do Minh Thai Nguyen Duc Thang Nguyen Phuong Nam Nguyen Thanh Tam Nguyen Thi Hiep Nguyen Van Hoa Tran Truong Dinh Thao Tu Thi Tuyet Nga Organizing Institutions

Vietnam National Universities International University HCM City (VNU-HCM) of VNU-HCM

Honorary Chairs

Professor Phan Thanh Binh, President of Vietnam National Universities – HCM City Professor Ho Thanh Phong, Rector of International University VNU-HCM

Conference General Chair

Vo Van Toi, PhD Professor and Chair of Biomedical Engineering Department International University – Vietnam National Universities Quarter 6, Linh Trung, Thu Duc District, Ho Chi Minh City, Vietnam Tel: (84-8) - 37 24 42 70 Ext. 3237 Fax: (84-8) - 37 24 42 71 Email: [email protected] Website: www.hcmiu.edu.vn/bme VIII Organizing Institutions

Organizing Committee

Dang Van Phuoc, MD, PhD Professor, President of the School of Medicine Vietnam National Universities Ho Chi Minh City, Vietnam

Paolo Carloni, PhD Professor, Head of Laboratory Computational Biophysics German Research School for Simulation Sciences GmbH Jülich, Germany Hoang Dung, PhD Professor, Co-Director of Center for Molecular and Nanoarchitectures (MANAR), Vietnam National Universities Ho Chi Minh City, Vietnam

Marco Santello, PhD Professor, School of Biological and Health Systems Engineering Arizona State University, USA

Lawrence Trong-Huan Le, PhD Professor, Department of Radiology and Diagnostic Imaging University of Alberta, Edmonton, Canada

Fong-Chin Su, PhD President of Taiwanese Society of Biomedical Engineering, Director, Medical Device Innovation Center - a Global Center of Excellence, Ministry of Education, Distinguished Professor at National Cheng Kung University - Department of Biomedical Engineering, Taiwan

Nghiem Doan, PhD Oral Surgeon, Dental Sedationist & Specialist in Public Health Dentis- try, Queensland University of Technology, Australia

Vo Van Toi, PhD Professor and Chair of Biomedical Engineering Department International University Vietnam National Universities Ho Chi Minh City, Vietnam Organizing Institutions IX

Scientific Committee

Ali Zulf Teesside University’s Graduate Research School UK Anders Wolff Department of Micro and Nanotechnology, Technical University of Denmark (DTU-nanotech), Denmark Anja Boisen Head of Nano section, Department of Micro and nanotechnology, Technical University of Denmark, Denmark Akihiro Kishimura Kyushu University, Japan Asha Shekaran Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, USA Atsushi Maruyama Tokyo Institute of Technology, Japan Brian Lau Department of Biomedical Engineering, Duke University, USA Bengang Xing Nanyang Technological University, Singapore Chang Young-Tae National University of Singapore, Singapore Christian Langton Institute of Health & Biomedical Innovation, Queensland University of Technology, Australia Christophe Moser Microengineering department, EPFL, Switzerland Christian Griesinger Max Planck Institute for Biophysical Chemistry, Germany Dang Duong Bang Laboratory of Applied Micro and nanotechnology (LAMINATE), Diagnostics Engineering, Division of Food Microbiology, National Food Institute, Technical University of Denmark David Leavesley Queensland University of Technology, Australia Dominique Pioletti Director of the Laboratory of Biomechanical Orthopedics, EPFL, Switzerland Fong-Chin Su Taiwanese Society of Biomedical Engineering, Medical Device Innovation Center, National Cheng Kung University, Taiwan Glen S.Kwon University of Wisconsin, Madison, USA Giuseppe Legname Neurobiology Sector, SISSA, Trieste, Italy Hoang Anh Dao Falculty of Odontostomatology, Hue University of Medicine and Pharmacy, Vietnam Hoang Dung Vietnam National Universities, Ho Chi Minh City, Vietnam Janez Plavec Slovenian NMR Centre, National Institute of Chemistry, Slovenia Jae-Seung Lee Korea University, Korea Jonathan Kaufman CyberLogic, Inc., USA Kang Lifeng Department of Pharmacy, National University of Singapore, Singapore Kazunari Akiyoshi Kyoto University, Japan Kazuo Nagasawa Tokyo University of Agriculture & Technology, Japan Keith Blackwood Institute of Health & Biomedical Innovation, Queensland University of Technology, Australia Le Thi Ly International University, VNU-HCMC, Vietnam Luiz E. Bertassoni Faculty of Dentistry, University of Sydney, Australia Lawrence Trong-Huan Le University of Alberta, Canada Marco Santello School of Biological and Health Systems Engineering, Arizona State University, USA Maria Laura Bolognesi Dipartimento di Farmacia e Biotecnologie, Italy Masayuki Yamato Tokyo Women’s Medical University, Japan Mia Woodruff Queensland University of Technology, Australia X Organizing Institutions

Michael Canva Directeur de Recherches au CNRS, Laboratoire Charles Fabry de l’Institut d’Optique Campus Polytechnique, France Michinao Hashimoto Singapore University of Technology and Design Naoki Sugimoto Konan University, Japan Nguyen Vu Hieu University of Paris, France Nguyen Thi Hiep International University, VNU-HCMC, Vietnam Nguyen Thi Hue International University, VNU-HCMC, Vietnam Nguyen Duc Thang International University, VNU-HCMC, Vietnam Nguyen Hoang Khue Tu International University, VNU-HCMC, Vietnam Nguyen Thanh Hai HCMC University of Technical Education, Vietnam Nghiem Doan Institute of Health & Biomedical Innovation, Queensland University of Technology, Australia Nikos Stergiopulos Laboratory of Hemodynamics and Cardiovascular Technology, Swiss Federal Institute of Technology, EFPL, Switzerland Anh Hoang Harvard Medical School, Massachusetts General Hospital, USA Phan Anh Tuan Nanyang Technological University, Singapore Paolo Carloni German Research School for Simulation Sciences GmbH and Institute for Advanced Simulation (IAS), Germany Phuoc Long Truong Nanobiotechnology Lab Department of Chemical and Biological Engineering Korea University, South Korea Ratko Magjarevic President, IFMBE (International Federation for Medical and Biological Engineering) Robert A. Lieberman President, Intelligent Optical Systems, Inc. Sara Richter University of Padua, Italy Shawn Tan Institute of Materials Research and Engineering, A*STAR, Singapore Stefano Sensi University of California, USA Takao Aoyagi MANA Coordinator, Nano-Bio Field, MANA, National Institute for Materials Science, Japan Thanh D Nguyen Massachusetts Institute of Technology Tram Dang Institute of Medical Biology, A*STAR, Singapore, School of Chemical & Biomedical Engineering, Nanyang Technology University, Singapore Tran Quang Hung Department of Micro and Nanotechnology, Technical University of Denmark (DTU-nanotech), Denmark Tran Ha Lien Phuong International University, VNU-HCMC, Vietnam Tran Truong Dinh Thao International University, VNU-HCMC, Vietnam Uyen Minh Le Department of Pharmaceutical Sciences, College of Pharmacy, Sullivan University, USA Vincent Pizziconi School of Biological and Health Systems Engineering, Arizona State University, USA Vo-Dinh Tuan Director, Fitzpatrick Institute for Photonics R. Eugene and Susie E. Goodson Distinguished Professor of Biomedical Engineering Duke University, USA Vo Van Toi International University, VNU-HCMC, Vietnam Xu Chenjie School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore Organizing Institutions XI

Xuewei Liu Nanyang Technological University, Singapore Yin Xiao Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Australia Yukio Nagasaki University of Tsukuba, Japan Yutaka Ikeda Department of Materials Science, University of Tsukuba, Japan Zhang Jun Physics and Applied Physics Division, School of Physical and Mathematical Science, Nanyang Technology University, Singapore Zhibin Du Institute of Health & Biomedical Innovation, Queensland University of Technology, Australia

Local Organizing Committee (LOC) & Secretary

Prof. Phan Thanh Binh Vietnam National Universities, Ho Chi Minh City, Honorary Chair Prof. Ho Thanh Phong International University-VNU-HCM, Honorary Chair Prof. Hoang Dung Vietnam National Universities, Ho Chi Minh City, Co-Organizer Prof. Vo Van Toi International University-VNU-HCM, Conference General Chair Dr. Nguyen Hong Quang International University- VNU-HCM, LOC Co-Chair Dr. Tran Ha Lien Phuong International University-VNU-HCM, LOC Chair Dr. Nguyen Trong Nam International University-VNU-HCM, External and Public Relations Chair Dr. Nguyen Duc Thang International University-VNU-HCM, Poster, Sponsorship and Exhibition coordinator Dr. Tran Truong Dinh Thao International University-VNU-HCM, General coordinator Dr. Nguyen Thi Hiep International University-VNU-HCM, Volunteer coordinator Ms. Hoang Van International University-VNU-HCM, Facility manager Ms. Tran Thi Thanh Lich International University-VNU-HCM, Financial manager Mr. Dong Quang Vinh International University-VNU-HCM, Research and development coordinator Ms. Nguyen Anh Dao International University-VNU-HCM, Conference design consultant Mr. Nguyen Thanh Tam International University-VNU-HCM, Website manager Mr. Nguyen Phuong Nam International University-VNU-HCM, Poster and Exhibition coordinator Mr. Nguyen Van Hoa International University-VNU-HCM, Proceedings editing team Mr. Do Minh Thai International University-VNU-HCM, Facility coordinator Ms. Tu Thi Tuyet Nga International University-VNU-HCM, Conference Secretary XII Organizing Institutions

Acknowledgements

We would like to express our deepest appreciation to the following sponsors:

Table of Contents

Development of Individual Plasmonic Nanosensors for Clinical Diagnosis ...... 1 Phuoc Long Truong and Sang Jun Sim

YALES2BIO: A Computational Fluid Dynamics Software Dedicated to the Prediction of Blood Flows in Biomedical Devices ...... 7 S. Mendez, C. Chnafa, E. Gibaud, J. Sigüenza, V. Moureau, and F. Nicoud

Numerical and Experimental Mixing Studies in a Split and Recombine Micromixer with Ellipse-Like Micropillars .... 11 Nhut Tran-Minh, Erik Andrew Johannessen, and Frank Karlsen

Multiplex DNA Biosensor for Viral Infection Diagnosis Using SERS Molecular Sentinel-on-Chip ...... 15 Hoan T. Ngo, Hsin-Neng Wang, Thomas Burke, Christopher Woods, Geoffrey S. Ginsburg, and Tuan Vo-Dinh

Whispering Gallery Mode Biosensing – A Detailed Study on ZnO Microspheres ...... 21 Ngo Huynh Buu Trong, Paul Ching-Hang Chien, Yu-Da Chen, Shang-Hsuan Wu, Fu-Chen Hsiao, Linh-Nam Nguyen, and Yia-Chung Chang

Ultrasonic Assessment of the Radius ...... 25 J.J. Kaufman, G.M. Luo, F. Rosete, M. Bucovsky, E.M. Stein, E. Shane, and R.S. Siffert

High-Resolution Imaging of Dispersive Ultrasonic Guided Waves in Human Long Bones Using Regularized Radon Transforms ...... 28 Tho N.H.T. Tran, Lawrence H. Le, and Mauricio D. Sacchi

Adaptive Noise Cancellation in the Intercept Time-Slowness Domain for Eliminating Ultrasonic Crosstalk in a Transducer Array ...... 32 K.C.T. Nguyen, Lawrence H. Le, Mauricio D. Sacchi, L.Q. Huynh, and E. Lou

Simulation of Ultrasound Propagation in Long Bone with Depth-Varying Porosity ...... 36 Vu-Hieu Nguyen and Salah Naili

Frequency Independence of Ultrasound Transit Time Spectroscopy ...... 39 M.-L. Wille and C.M. Langton

In Vitro Ultrasonic Assessment of the Biomechanical Quality of the Interface Surrounding a Dental Implant ...... 43 R. Vayron and G. Haiat

Silicon-Based Fabrication of Biodegradable Polymer for Controlled Drug-Delivery ...... 47 Thanh D. Nguyen, Robert S. Langer, and Ana Jaklenec

Advancement in Gemcitabine Delivery for Cancer Treatment ...... 51 Uyen Minh Le

Multifunctional Drug Nanosystems: A Summary of Recent Researches at IMS/VAST ...... 55 X.P. Nguyen, T.T. TMai, P.T. Ha, H.N. Pham, H.N. Luu, H.M. Do, D.L. Tran, H.N. Nguyen, L.T. Nguyen, A.S. Ho, and T.M.N. Hoang

Preparation, Characterization and Antibacterial Curcumin Encapsulated Chitosan-PAA Silver Nanocomposite Films ... 58 N.V. Cuong, P.N.N. Han, N.K. Hoang, and N.N.L. Giang XIV Table of Contents

Monitoring through Tissue the De-gelation of Alginate Gels by Different De-gelling Agents ...... 62 K.V.T. Nguyen and J.N. Anker

Use of Super Paramagnetic Iron-Oxide Nanoparticles in the Treatment of Atherosclerosis ...... 67 S. Chandramouli, S. Sanjana, and S. Swathi

Effect of pH on the Synthesis of Fucoidan-coated Magnetic Iron Oxide Nanoparticles for Biomedical Applications .... 71 Khanh Nghia Tran, Phuong Ha-Lien Tran, Toi Van Vo, and Thao Truong-Dinh Tran

A Novel Non-invasive System for Acquiring Jugular Venous Pulse Waveforms ...... 75 Tam Nguyen, Anh Dinh, Francis M. Bui, and Toi Vo

Remote Monitoring of Cardiac Rhythm Management Devices in Vietnam The Role of the Biomedical Engineer ...... 79 Tran Thong

Inspired Sinewave Technique: A Novel Technology to Measure Cardiopulmonary Function ...... 83 Phi Anh Phan, Cathy Zhang, Daniel Geer, Clive Hahn, and Andrew Farmery

Wireless Sensor Network for Real Time Healthcare Monitoring: Network Design and Performance Evaluation Simulation ...... 87 Minh-Thanh Vo, T.T. Thanh Nghi, Van-Su Tran, Linh Mai, and Chi-Thong Le

Estimation of Guidewire Inclination Angle for 3D Reconstruction ...... 92 T. Petkovic ´ and S. Lonˇcari´c

Intelligent Heart Rate Variability Processing System ...... 96 Hoang ChuDuc, Thuan NguyenDuc, Kien NguyenPhan, and Ha NguyenThai

Analysis of Sleep Macro - and Microstructure ...... 100 Le Quoc Khai, Nguyen Thi Minh Huong, and Huynh Quang Linh

Design System to Remotely Monitor Patients with Parkinson’s Disease ...... 104 Hai Tuyen Nguyen, Cao Cuong Vu, Van Quyet Phan, Viet Dung Nguyen, and The Dung Nguyen

Implementation of Telemedicine ECG System Based on Bluetooth Android Device ...... 108 Hung Ngoc Do, Minh-Thanh Vo, Tinh Duy Ho, and Thanh-Tam Nguyen

On Designing a System to Supervise Patients’ Vital Signs through Wireless Sensor Network ...... 113 N.T. Dung, P.T. Nghia, D.Q. Long, N.H. Tuyen, N.V. Dung, and N.T. Ha

FPGA Implementation for Cardiac Excitation-Conduction Simulation Based on FitzHugh-Nagumo Model ...... 117 Nur Atiqah Adon, Mohamad Hairol Jabbar, and Farhanahani Mahmud

Determination of the Neutral Axis in Total Ankle Replacement ...... 121 Ha Vo, Barry Tuvel, Bich Nguyen, and Trung Le

Improving Electrospun Fibre Stacking with Direct Writing for Developing Scaffolds for Tissue Engineering for Non-load Bearing Bone ...... 125 K.A. Blackwood, N. Ristovski, S. Liao, N. Bock, J. Ren, G.T.S. Kirby, M.M. Stevens, R. Steck, and M.A. Woodruff

A Comprehensive Evaluation of Flapless Dental Implant Treatment in Posterior Maxilla and the Conservative Regeneration of Bone in Osteoporotic Rats ...... 129 N. Doan, Z. Du, J. Xiao, W. Xia, R. Crawford, P. Reher, S. Ivanovski, F. Yan, J. Chen, and Y. Xiao Table of Contents XV

A Measure of Clinical Outcomes in Dental Implant Surgery Flapless Surgery versus Flap Technique in Posterior Maxilla of Post Menopause Women ...... 133 M. Nguyen, N. Doan, Z. Du, P. Reher, and Y. Xiao

An Analysis of Exosomes from Keratinocytes and Fibroblasts ...... 137 Uyen Thi Trang Than, Dominic Guanzon, Lucas Wager, Kerry J. Manton, Brett Hollier, and David Leavesley

Oral Health Problems among Adult Patients at Commune Health Centres in Central Vietnam: Prevalence and Care Seeking Behaviour ...... 142 Hoang Anh Dao, Peter Hill, Ngo Hien, and Nguyen Toai

Treatment Outcomes of Periapical Lesions in Permanent Incisors Treated with Calcium Hydroxide ...... 147 Thai Van Nguyen and Thao Quy Le

The Primary Results of the N2/Ar Micro-plasma Exposure on Second Degree Wound Healing ...... 151 Minh-Hien Ngo, Pei-Lin Shao, and Jiunn-Der Liao

Novel Approaches to Diagnosis and Therapy in Neurodegenerative Diseases ...... 155 Giuseppe Legname

A Reliable Semi-automatic Program to Measure the Vertebral Rotation Using the Center of Lamina for Adolescent Idiopathic Scoliosis ...... 159 W. Chen, E. Lou, and Lawrence H. Le

Investigation of the Optimal Freehand Three-Dimensional Ultrasound Configuration to Image Scoliosis: An In-vitro Study ...... 163 Q.N. Vo, E. Lou, Lawrence H. Le, and L.Q. Huynh

Assessment of Curve Flexibility by Ultrasonic Imaging – A Pilot Study ...... 167 R. Zheng, E. Lou, Lawrence H. Le, D. Hedden, J. Mahood, and M. Moreau

Prefrontal fNIRS Neuroimaging during a Sleep Induction Task Using Perception of a Red Light through Closed Eyes to Fight Insomnia: A Pilot Study ...... 171 P.A. Grounauer and B. Métraux

Orthogonal Digital Radiographs - A Novel Template for a Paediatric Femur Finite Element Model Development ...... 175 D.S. Angadi, D.E.T. Shepherd, R. Vadivelu, and T.G. Barrett

EEG Signal Analysis and Artifact Removal by Wavelet Transform ...... 179 Pham Phuc Ngoc, Vu Duy Hai, Nguyen Chi Bach, and Pham Van Binh

Detection of Activities Daily Living and Falls Using Combination Accelerometer and Gyroscope ...... 184 Quoc T. Huynh, Uyen D. Nguyen, Kieu Trung Liem, and Binh Q. Tran

Using Near-Infrared Technique for Vein Imaging ...... 190 Tran Van Tien, Pham T.H. Mien, Pham T. Dung, and Huynh Quang Linh

Ribs Suppression in Chest X-Ray Images by Using ICA Method ...... 194 Hieu Xuan Nguyen and Tin Thanh Dang

Ultrasound Ovary Image Classification Using Kσ-Classifier ...... 198 B.S. Usha and S. Sandya XVI Table of Contents

FPGA-in-the-Loop Simulation of Cardiac Excitation Modeling towards Real-Time Simulation ...... 203 Norliza Othman, Mohamad Hairol Jabbar, Abd Kadir Mahamad, and Farhanahani Mahmud

G-Quadruplexes in the Human Immunodeficiency Virus-1 and Herpes Simplex Virus-1: New Targets for Antiviral Activity by Small Molecules ...... 207 Rosalba Perrone, Sara Artusi, Elena Butovskaya, Matteo Nadai, Christophe Pannecouque, and Sara N. Richter

Cell Specific Imaging Probe Development and Biomedical Applications ...... 211 Nam-Young Kang and Young-Tae Chang

A Case Study on Expression of Single-Chain Variable Fragment of Anti-HER2 Antibody by Using Recombinant Baculovirus in Silkworms ...... 215 T.M.H. Nguyen, T.V.A. Nguyen, T.H. Le, T.H. La, T.T.B. Nguyen, and Q.H. Le

DNA Hypermethylation Signatures for Detection of Breast Cancer in Vietnamese Population ...... 219 T.K. Phuong, L.D. Thuan, D.T.P. Thao, and L.H.A. Thuy

Interaction between XG and HPC in Blended-HPC/H2O/H3PO4 Tertiary System...... 223 S.P. Rwei, T.A. Nguyen, and H.W. Wu

The Time Based Study of Cell Morphology Using Atomic Force Microscopy ...... 227 Wan Ibtisam Wan Omar and Chin Fhong Soon

The Effects of Enzyme to the Dissociation of Cells in Monolayer and 3D Microtissue on the Liquid Crystal Substrate ...... 231 Kok Tung Thong, Chin Fhong Soon, and Kian Sek Tee

Microscale Tribological Response of Human Osteoarthritic Articular Cartilage under the Boundary Lubrication of Hyaluronic Acid ...... 235 Cong-Truyen Duong and Duc-Nam Nguyen

Single Cell Traction Force Mapping Software ...... 239 Chin Fhong Soon, Kian Sek Tee, Mansour Youseffi, and Morgan Denyer

Growth of Rutile Phased Titanium Dioxide (TiO2) Nanoflowers for HeLa Cells Treatment ...... 243 N.S. Khalid, W.S. WanZaki, and M.K. Ahmad

Cystatin C Versus Creatinine in Evaluating Glomerular Filtration Rate in Renal Transplant Recipients with Proteinuria ...... 247 Tran Thai Thanh Tam, Hoang Khac Chuan, Du Thi Ngoc Thu, Nguyen Thi Thai Ha, Thai Minh Sam, Nguyen Thi Le, and Tran Ngoc Sinh

Genetic Mutation Types Detected in 25 Blood Samples of KHMER Patient with Beta-thalassemia in Bac Lieu Province ...... 253 Pham Thi Ngoc Nga and Nguyen Trung Kien

Using Realtime Rt-Pcr and Sequencing Assays to Define Viral Load, Types and Subtypes of Hepatitis C Virus at Cantho Center General Hospital ...... 257 Cao Thi Tai Nguyen, Tran Ngoc Dung, and Nguyen Thi Huynh Nga

Role of the Fifth Copper Binding Site in Prion Conversion ...... 261 Thao Phuong Mai and Giuseppe Legname Table of Contents XVII

The Electrocardiographic Characteristics of Chronic Obstructive Pulmonary Outpatients ...... 266 Dang Huynh Anh Thu and Le Thi Tuyet Lan

The Correlation between Peripheral Nerve Conduction Study Parametersand Level of Urinary Albumin Excretionin Diabetic Patients ...... 270 Tran Vu Hoang Duong, Le Quoc Tuan, and Nguyen Thi Le

New Practical Approachs to Estimation of Glomerular Filtration Rate in Adult: A Review ...... 274 Le Quoc Tuan, Vo Thi Thien Huong, and Nguyen Thi Le

Testosterone – The Vital Hormone of Men: A Review...... 278 Tran Ngoc Thanh and Pham Dinh Luu

Roles of Testosterone in Men with Type 2 Diabetes: A Review ...... 281 Tran Ngoc Thanh and Pham Dinh Luu

Investigating Chronic Obstructive Pulmonary Disease (COPD) in Vietnamese Patients Using Impulse Oscillometry (IOS) ...... 285 T.X. Tan, V. Van Toi, Truong Quang Dang Khoa, H.D.H. Hanh, T.T.K. Thu, and L.T.T. Lan

Finite-Difference Time-Domain Simulations of Ultrasound Backscattered Waves in Cancellous Bone ...... 289 A. Hosokawa

Investigation of Solid Dispersion Methods to Improve the Dissolution Rate of Curcumin ...... 293 Kiet Anh Tran, Thao Truong-Dinh Tran, Toi Van Vo, Thanh Van Tran, and Phuong Ha-Lien Tran

Dissolution Enhancement of Curcumin by Solid Dispersion with Polyethylene Glycol 6000 and Hydroxypropyl Methylcellulose ...... 298 Tuong Ngoc-Gia Nguyen, Phuong Ha-Lien Tran, Toi Van Vo, Thanh Van Tran, and Thao Truong-Dinh Tran

Improvement of Gliclazide Dissolution Rate Using In Situ Micronization Technique ...... 302 Nguyen Thanh Nhan and Tran Van Thanh

Research and Preparation of Solid Dispersion of Itraconazole in Hydroxypropyl-Beta-Cyclodextrin ...... 306 Tran Van-Thanh, Pham Vu Quang Vinh, and Huynh Van-Hoa

A Potential Application of Vietnamese Rice in Pharmaceutical Industry as a Sustained Release Agent ...... 311 Vuong Duy Ngo, Thao Truong-Dinh Tran, Toi Van Vo, and Phuong Ha-Lien Tran

Use of Microwave Method for Controlling Drug Release of Modified Sprouted Rice Starch ...... 314 Thinh Duc Luu, Nam Hoang Phan, Thao Truong-Dinh Tran, Toi Van Vo, and Phuong Ha-Lien Tran

Fabrication of In Situ Cross-Linking Polyvinyl Phosphonic Acid - Chitosan Hydrogel for Wound Applications ...... 317 Le Quoc Tuan, Dang Hoang Phuc, Vo Van Toi, and Thi-Hiep Nguyen

Development of a New Injectable PVA–Ag NPs/ Chitosan Hydrogel for Wound Dressing Application ...... 321 Xuan-Truong Nguyen, Vo Van Toi, and Thi-Hiep Nguyen

Investigation of the Silk Fiber Extraction Process from the Vietnam Natural Bombyx Mori Silkworm Cocoon ...... 325 Thu-Hien Luong, Thao-Nhi Ngoc Dang, Oanh Pham Thi Ngoc, Thanh-Ha Dinh-Thuy, Thi-Hiep Nguyen, Vo Van Toi, Hoang Thuy Duong, and Hoang Le Son

Fabrication of Hyaluronan – Chitosan – Polyvinyl Phosphonic Acid Hydrogel for Bioglue Applications ...... 329 Dang Hoang Phuc, Thi-Hiep Nguyen, Vo Van Toi, and Phan Van Tien XVIII Table of Contents

Investigation of the Synthetic Process of Nano-Hydroxyapatite (Hap) Using Microwave and Ultrasound ...... 332 Tran Thi Tuong Van, Bui Ngoc Thao Tram, Vo Van Toi, and Thi-Hiep Nguyen

Synthesis and Characterization of Hydroxyapatite Biomaterials from Bio Wastes ...... 336 Bui Ngoc Thao Tram, Thi-Hiep Nguyen, and Vo Van Toi

Modified DNA Extraction Method for the Detection of Aspergillus Flavus and Aspergillus Parasiticus in Dried Foods...... 339 Pham Tuong Vi, Huynh Le Thao Trinh, and Nguyen Thi Hue

DEMM: A Meta-Algorithm to Predict the pKa of Ionizable Amino Acids in Proteins ...... 343 T.B. Nguyen, K.P. Tan, and M.S. Madhusudhan

A Threshold Algorithm in a Fall Alert System for Elderly People ...... 347 Pham Ty Phu, Nguyen Thanh Hai, and Nguyen Thanh Tam

Comparative Study on Human A-Glucosidase ...... 351 Q. Ong and L. Le

Development of Non-Invasion Method for Prognosis and Early Diagnosis of Cervical Cancer in Vietnamese Patients BasedonDNAMethylationSpecificPCR...... 355 T.K. Phuong, L.D. Thuan, and L.H.A. Thuy

Antifungal Activity of Conyza Canadensis ((L.) Cronquist) Collected in Northern Viet Nam ...... 359 N.B. Phuong, N.T.T. Lien, and N.T.T. Hoai

Antimicrobial Activity of Senna alata (l.), Rhinacanthus nasutus and Chromolaena odorata (l.) Collected in Southern Vietnam ...... 362 Thuong L.H. Pham, Trung T. Trinh, and Hoai T.T. Nguyen

Evaluation of the Optimal Multiplex PCR Method for the Detection of Aspergillus Flavus and Aspergillus Parasiticus on Dried Peanut...... 367 Nghia T. Le, Trinh Huynh, and Hue T. Nguyen

Evaluation of the Optimal Multiplex PCR Method for the Detection of Aspergillus Flavus and Aspergillus Parasiticus on Dried Corn ...... 371 Tu T. Ly, Trinh Huynh, and Hue T. Nguyen fNIRS-Based Wavelet Thresholds for Motor Area Determination ...... 376 Dao.V. Ha, Hai T. Nguyen, Cuong.Q. Ngo, Mai T. Tran, and Toi Van Vo

Determining the Size of a Solid Tumor ...... 381 Tran Thi Quynh Nhu, Nguyen Thanh Hai, Ngo Thanh Dong, and Nguyen Tan Nhu

2D Complex Shear Modulus Imaging in Gaussian Noise ...... 385 Nguyen Thi Anh-Dao, Tran Duc-Tan, and Nguyen Linh-Trung

Evaluation of Frontal and Visual Cortices on Mental Working Tasks Using Functional Near Infrared Spectroscopy .... 389 Pham Thanh Thao, Nguyen Duc Thang, and Vo Van Toi

Differentiation of Hemodynamic Responses of the Brain with Typing and Writing ...... 395 Vo Nhut Tuan, Nguyen Duc Thang, Vo Van Toi, Tran Le Giang, Nguyen Huynh Minh Tam, and Dinh Dong Luong Table of Contents XIX

The Relation between a Three-Day Sitting Meditation Fasting and the Participant’s Psychophysiological Condition: Through Nonlinear Chaos Analysis of Pulse Waves ...... 399 T. Futaba

Construction of Phantom Mimic Vessel for Study of Human Vessel Conditions in Deep Vein Thrombosis (DVT) ...... 402 N. Ibrahim, W.N. Wan Zakaria, N. Aziz, and M.K. Abdullah

Medical Image Contour Based Context-Aware in Contourlet Domain ...... 405 Nguyen Thanh Binh

Nonrigid Point Set Registration-Based 3-D Human Pose Tracking from Depth Data ...... 409 Dong-Luong Dinh, Nguyen Duc Thang, Sungyoung Lee, and Tae-Seong Kim

Kinematics of High-Heeled Running Gait with Consideration for Experience of Wearers ...... 414 Y.Q. Song, F.L. Li, J.S. Li, and Y.D. Gu

MFCC-DTW Algorithm for Speech Recognition in an Intelligent Wheelchair ...... 417 Le Hoang Linh, Nguyen Thanh Hai, Ngo Van Thuyen, Tran Thanh Mai, and Vo Van Toi

Lower Limb Kinematics Study on Female Latin Shoes of Different Height Heels ...... 422 S.R. Shao, X.X. Gao, Y. Zhang, Q.C. Mei, and Y.D. Gu

Ideal Cross-Point Regions of Prediction Errors from LOCO-I Algorithm Applied to Lossless Image Compression ..... 426 Tin T. Dang and Canh Xuan Huynh

Applying the Image Compression Algorithm of ICRICM to a Plugin Integrated into MIPAV Software ...... 430 Tin T. Dang and Khoa Anh Tran

Software Design for Training and Supporting Knowledge of Ventilators for Clinical Engineers ...... 434 Nguyen Nhan Thien and Huynh Quang Linh

Design of Electrotherapy Equipment Using Wireless Communication ...... 437 Nguyen Tuan Anh and Huynh Quang Linh

Experimental Determination of the Loss of Total Endoprosthesis Polyethylene Cup Using Holographic Interferometry ...... 440 M. Houfek and L. Houfek

The Applications of Control System Approach in Biomedical Engineering Research ...... 444 Huynh Luong Nghia and Nguyen Van Trung

Study of Vessel Conditions for Deep Vein Thrombosis (DVT) Diagnosis According to Body Mass Index ...... 447 W.N. Wan Zakaria, N. Ibrahim, N. Mat Harun, Razali Tomari, and M.K. Abdullah

Tensile Stress Analyses of the Hip Joint Endoprosthesis Ceramic Head with Real Shape Deviations ...... 450 V. F u is

Review and Development of Tetraplegic-Musculoskeletal FES-Elbow Joint Extension Control Strategies ...... 454 N.H.M. Nasir, M.K.I. Ahmad, B.S.K.K Ibrahim, and F. Sherwani

Integrated Biomedical Waste Management for Small Scale Healthcare Units in India ...... 458 Prasad Balachandran XX Table of Contents

Simultaneous Detection of Two Viroids Infecting Grapevines in Taiwan by Multiplex RT-PCR ...... 461 Nguyen Phuc Thien and Chu-Hui Chiang

Theoretical Investigation on Antioxidant Activity of Phenolic Compounds Extracted from Artocarpus Altilis ...... 464 Nguyen Minh Thong and Pham Cam Nam

An EEG-Controlled Wheelchair Using Eye Movements ...... 470 Hue T. Tran, Hai T. Nguyen, Hieu V. Phan, V. Van Toi, Thuyen V. Ngo, and Cao Bui-Thu

Application of Fluorescence Photography in the Evaluation of Acne ...... 474 Pham Thi Hai Mien, Tran Van Tien, Vu Thanh Huy, and Huynh Quang Linh

Digital Morphology Comparisons between Models of Conventional Intraoral Casting and Digital Rapid Prototyping ... 478 Rong-Fu Kuo, Shing-Jye Chen, Tung-Yiu Wong, Bo-Cheng Lu, and Zheng-Han Huang

Human Activity Recognition and Monitoring Using Smartphones ...... 481 Vu Ngoc Thanh Sang, Nguyen Duc Thang, Vo Van Toi, Nguyen Duc Hoang, and Truong Quang Dang Khoa

Evaluation of Hemodynamic Responses to Visual Tasks Using Functional Near Infrared Spectroscopy ...... 486 Tran Le Giang, Nguyen Duc Thang, Vo Van Toi, Nguyen Huynh Minh Tam, Dinh Dong Luong, and Truong Quang Dang Khoa

Investigation the Stability of Oblique Fracture Fixation of Long Bone Using Different Screw Angle ...... 491 Bich Nguyen, Trung Le, and Ha Van Vo

F-Scan Analysis of Prosthetic Fittings through Mercer on Mission Vietnam ...... 495 Emily Brett, Matthew Yin, Ha Van Vo, Edward O’Brien, Loren Sumner, and Philip McCreanor

Biomechanical Evaluation of Hybrid Bicortical and Unicortical Screw and Bone Plate Fixation in Humeral Mid-Shaft Fractures: A Study on Cadaveric Bone ...... 499 Trung Le, Benjamin McDeed, and Ha Van Vo

Novel Design of a Prosthetic Foot Using Spring Mechanism ...... 503 Awab Umar Khan and Ha Van Vo

Development and Characterization of Porous Calcium Phosphate Cement Using α-Tricalcium Phosphate Bead ...... 507 Pham Trung Kien, Tsuru Kanji, and Kunio Ishikawa

Author Index ...... 511

Keyword Index ...... 515