Anti-EFCAB6 polyclonal antibody (DPAB-DC2864) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description This encodes a which directly binds the oncogene DJ-1 and to form a ternary complex in cells. This binding protein recruits histone-deacetylase complexes in order to repress transcription activity of androgen receptor. This protein may also play a role in spermatogenesis and fertilization. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen Recombinant protein corresponding to amino acids of human EFCAB6. The sequence is QQSTEKAVAARDKLMDRHQDISKAFTKTDQSKTNYISICKMQEVLEECGCSLTEGELTHLLNSW GVSRHDNAINYLDFLRAVENSKSTGAQPKEKEESMPINFATLNPQEVVRKIQEVVESSQLALSTA FSALDKEDT

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Antigen affinity purification

Conjugate Unconjugated

Applications IHC-P,

Format Liquid

Size 100 μl

Buffer In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)

Preservative 0.02% Sodium Azide

Storage Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

GENE INFORMATION

Gene Name EFCAB6 EF-hand calcium binding domain 6 [ Homo sapiens (human) ]

Official Symbol EFCAB6

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Synonyms EFCAB6; EF-hand calcium binding domain 6; DJBP; HSCBCIP1; dJ185D5.1; EF-hand calcium- binding domain-containing protein 6; DJ-1-binding protein; CAP-binding protein complex- interacting protein 1;

Entrez Gene ID 64800

Protein Refseq NP_073622

UniProt ID Q5THR3

Chromosome Location 22q13.2

Pathway Androgen receptor signaling pathway;

Function calcium ion binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved