Toxicological Profile for Barium and Barium Compounds
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Barium Chloride Dihydrate
NATIONAL TOXICOLOGY PROGRAM Technical Report Series No. 432 TOXICOLOGY AND CARCINOGENESIS STUDIES OF BARIUM CHLORIDE DIHYDRATE (CAS NO. 10326-27-9) IN F344/N RATS AND B6C3Fl MICE (DRINKING WATER STUDIES) U.S. DEPARTMENT OF HEALTE AND HUMAN SERVICES Public Health Service National Institutes of Health FOREWORD The National Toxicology Program (NTP) is made up of four charter agencies of the U.S. Department of Health and Human Services (DHHS): the National Cancer Institute (NCI), National Institutes of Health; the National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health; the National Center for Toxicological Research (NCTR), Food and Drug Administration; and the National Institute for Occupational Safety and Health (NIOSH), Centers for Disease Control. In July 1981, the Carcinogenesis Bioassay Testing Program, NCI, was transferred to the NIEHS. The NTP coordinates the relevant programs, staff, and resources from these Public Health Service agencies relating to basic and applied research and to biological assay development and validation. The NTP develops, evaluates, and disseminates scientific information about potentially toxic and hazardous chemicals. This knowledge is used for protecting the health of the American people and for the primary prevention of disease. The studies described in this Technical Report were performed under the direction of the NIEHS and were conducted in compliance with NTP laboratory health and safety requirements and must meet or exceed all applicable federal, state, and local health and safety regulations. Animal care and use were in accordance with the Public Health Service Policy on Humane Care and Useof Animals. The prechronic and chronic studies were conducted in compliancewith Food and Drug Administration(FDA) Good Laboratory Practice Regulations, and all aspects of the chronic studies were subjectedto retrospective quality assurance audits before being presented for public review. -
Barium Acetate
Barium acetate sc-202968 Material Safety Data Sheet Hazard Alert Code Key: EXTREME HIGH MODERATE LOW Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME Barium acetate STATEMENT OF HAZARDOUS NATURE CONSIDERED A HAZARDOUS SUBSTANCE ACCORDING TO OSHA 29 CFR 1910.1200. NFPA FLAMMABILITY1 HEALTH2 HAZARD INSTABILITY0 SUPPLIER Company: Santa Cruz Biotechnology, Inc. Address: 2145 Delaware Ave Santa Cruz, CA 95060 Telephone: 800.457.3801 or 831.457.3800 Emergency Tel: CHEMWATCH: From within the US and Canada: 877-715-9305 Emergency Tel: From outside the US and Canada: +800 2436 2255 (1-800-CHEMCALL) or call +613 9573 3112 PRODUCT USE Chemical reagent, acetates, mordant for printing fabrics, catalyst manufacturing, paint and varnish dryers, lubricating oil and grease additive. SYNONYMS C4-H6-O4-Ba, Ba(C2H3O2)2, "barium diacetate", "acetic acid barium salt", "octan barnaty" Section 2 - HAZARDS IDENTIFICATION CHEMWATCH HAZARD RATINGS Min Max Flammability: 1 Toxicity: 2 Body Contact: 2 Min/Nil=0 Low=1 Reactivity: 1 Moderate=2 High=3 Chronic: 2 Extreme=4 CANADIAN WHMIS SYMBOLS 1 of 12 EMERGENCY OVERVIEW RISK Harmful by inhalation and if swallowed. POTENTIAL HEALTH EFFECTS ACUTE HEALTH EFFECTS SWALLOWED ! Accidental ingestion of the material may be harmful; animal experiments indicate that ingestion of less than 150 gram may be fatal or may produce serious damage to the health of the individual. ! Ingestion of soluble barium compounds may result in ulceration of the mucous membranes of the gastrointestinal tract, tightness in the muscles of the face and neck, gastroenteritis, vomiting, diarrhea, muscular tremors and paralysis, anxiety, weakness, labored breathing, cardiac irregularity due to contractions of smooth striated and cardiac muscles (often violent and painful), slow irregular pulse, hypertension, convulsions and respiratory failure. -
Barium, Inorganic Water-Soluble Compounds
Barium, inorganic water-soluble compounds Evaluation of health hazards and proposal of health based quality criteria for soil and drinking water Environmental Project No. 1516, 2013 Title: Author: Barium, inorganic water-soluble compounds. Elsa Nielsen Evaluation of health hazards and proposal of Ole Ladefoged health based quality criteria for soil and drinking Division of Toxicology and Risk Assessment water National Food Institute, Technical University of Denmark Published by: The Danish Environmental Protection Agency Strandgade 29 1401 Copenhagen K Denmark www.mst.dk/english Year: ISBN no. Authored in 2006 978-87-93026-71-1 Published in 2013 Disclaimer: When the occasion arises, the Danish Environmental Protection Agency will publish reports and papers concerning research and development projects within the environmental sector, financed by study grants provided by the Danish Environmental Protection Agency. It should be noted that such publications do not necessarily reflect the position or opinion of the Danish Environmental Protection Agency. However, publication does indicate that, in the opinion of the Danish Environmental Protection Agency, the content represents an important contribution to the debate surrounding Danish environmental policy. Sources must be acknowledged. Content CONTENT 2 PREFACE 5 1 GENERAL DESCRIPTION 6 1.1 IDENTITY 6 1.2 PHYSICAL / CHEMICAL PROPERTIES 6 1.3 PRODUCTION AND USE 7 1.4 ENVIRONMENTAL OCCURRENCE 7 1.4.1 Air 7 1.4.2 Water 7 1.4.3 Soil 8 1.4.4 Foodstuffs 8 1.5 ENVIRONMENTAL FATE 8 1.5.1 Air 8 1.5.2 -
Transport of Dangerous Goods
ST/SG/AC.10/1/Rev.16 (Vol.I) Recommendations on the TRANSPORT OF DANGEROUS GOODS Model Regulations Volume I Sixteenth revised edition UNITED NATIONS New York and Geneva, 2009 NOTE The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the Secretariat of the United Nations concerning the legal status of any country, territory, city or area, or of its authorities, or concerning the delimitation of its frontiers or boundaries. ST/SG/AC.10/1/Rev.16 (Vol.I) Copyright © United Nations, 2009 All rights reserved. No part of this publication may, for sales purposes, be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, electrostatic, magnetic tape, mechanical, photocopying or otherwise, without prior permission in writing from the United Nations. UNITED NATIONS Sales No. E.09.VIII.2 ISBN 978-92-1-139136-7 (complete set of two volumes) ISSN 1014-5753 Volumes I and II not to be sold separately FOREWORD The Recommendations on the Transport of Dangerous Goods are addressed to governments and to the international organizations concerned with safety in the transport of dangerous goods. The first version, prepared by the United Nations Economic and Social Council's Committee of Experts on the Transport of Dangerous Goods, was published in 1956 (ST/ECA/43-E/CN.2/170). In response to developments in technology and the changing needs of users, they have been regularly amended and updated at succeeding sessions of the Committee of Experts pursuant to Resolution 645 G (XXIII) of 26 April 1957 of the Economic and Social Council and subsequent resolutions. -
Cool Reaction the Endothermic Reaction Between SCIENTIFIC Barium Hydroxide and Ammonium Thiocyanate
Cool Reaction The Endothermic Reaction Between SCIENTIFIC Barium Hydroxide and Ammonium Thiocyanate Introduction Many reactions produce heat, in fact when people think of chemical reactions, heat production is often expected. However, endothermic reactions, reactions which consume heat, can be just as exciting. One of the most striking examples of this is when the solids barium hydroxide and ammonium thiocyanate are mixed together in a beaker. Materials Ammonium thiocyanate, NH4SCN, 10 g Stirring rod Barium hydroxide octahydrate, Ba(OH)28H2O, 20 g Thermometer graduated to at least –30 °C Erlenmeyer flask, small, with stopper, or a 50-mL beaker Safety Precautions Barium salts are toxic by ingestion. Ammonium thiocyanate is also toxic by ingestion. Use caution when handling the beaker or flask. Use tongs if available. The temperatures involved are cold enough to freeze skin. Ammonia vapor is very irritating to eyes and the respiratory tract. Do not allow students to inhale this gas. Wear chemical splash goggles, chemical-resistant gloves, and a chemical-resistant apron. Please review current Material Safety Data Sheets for additional safety, handling, and disposal information. Procedure 1. Transfer 20 g of barium hydroxide and 10 g of ammonium thiocyanate to a flask and mix with a glass or plastic stirring rod. 2. In less than two minutes the solids become liquid. A thermometer placed in the mixture shows the temperature falling far below freezing. An ammonia odor is evident to all who are near the flask. 3. Place the flask in a small puddle of water and your students will clearly see just how cool this reaction is; the water will freeze the flask to the counter top. -
Writing Total and Net Ionic Equations
WRITING TOTAL AND NET IONIC EQUATIONS http://www.csun.edu/~hcchm001/FreshChemHandouts.html 1. Write the overall equation including the correct designations for the physical state of the substances (s, l, g, aq). Balance this equation. Most of these kinds of equations are double displacement reactions: AX + BY 6 AY + BX 2. For the total ionic equations, write strong electrolytes in solution in the form of aqueous ions. (a) Strong acids. The common strong acids and their aqueous ions are: HI Hydroiodic acid H+-(aq) + I (aq) HBr Hydrobromic acid H+-(aq) + Br (aq) HCl Hydrochloric acid H+-(aq) + Cl (aq) +- HNO33Nitric acid H (aq) + NO (aq) +- HClO44Perchloric acid H (aq) + ClO (aq) +-2 H24SO Sulfuric acid 2 H (aq) + SO4(aq) (b) Strong bases. Strong bases are the hydroxides of the alkali (Group IA) and alkaline earth (Group IIA) metals ions which are sufficiently soluble. The common strong bases and their aqueous ions are: LiOH Lithium hydroxide Li+-(aq) + OH (aq) NaOH Sodium hydroxide Na+-(aq) + OH (aq) KOH Potassium hydroxide K+-(aq) + OH (aq) +2 - Sr(OH)2Strontium hydroxide Sr (aq) + 2 OH (aq) +2 - Ba(OH)2 Barium hydroxide Ba (aq) + 2 OH (aq) (c) Soluble salts. Determinations of the solubility of a salt may be made by reference to SOLUBILITIES OF IONIC COMPOUNDS. Soluble salts are written as their aqueous ions: NaCl(aq) Sodium chloride Na+-(aq) + Cl (aq) +-2 K24SO (aq) Potassium sulfate 2 K (aq) + SO4(aq) +-2 Li23CO (aq) Lithium carbonate 2 Li (aq) + CO3(aq) +-3 Na34PO (aq) Sodium phosphate 3 Na (aq) + PO4(aq) +-2 (NH42) SO4(aq) Ammonium sulfate 2 NH4(aq) + SO4 (aq) 3. -
RFC: IRIS Barium and Compounds Substance File
October 29, 2002 Information Quality Guidelines Staff Mail Code 28221T U.S. EPA 1200 Pennsylvania Ave., N.W. Washington, DC, 20460 Subject: Request for Correction of the IRIS Barium and Compounds substance file - Information disseminated by EPA that does not comply with EPA or OMB Information Quality Guidelines Dear Madam or Sir; Chemical Products Corporation (CPC), a Georgia corporation which produces Barium and Strontium chemicals at its Cartersville, Georgia facility, hereby submits this Request for Correction (RFC) concerning EPA’s Integrated Risk Information System Barium and Compounds Substance File (IRIS Ba File). The influential information contained in this file fails to comply with the OMB “Guidelines for Ensuring and Maximizing the Quality, Objectivity, Utility, and Integrity of Information Disseminated by Federal Agencies”. The information disseminated in EPA’s IRIS Barium and Compounds file directly contradicts the information published by EPA in the January 3, 1997 Federal Register and, therefore, cannot represent an EPA consensus position. The IRIS Ba File was revised in 1998 and 1999, yet it contains no mention of the toxicological evaluation conducted by EPA’s Office of Pollution, Pesticides, and Toxic Substances reported in 62 FR 366-372 (No. 2, January 3, 1997). There is no explanation of how a radically different interpretation of the same data could be justified. The NOAEL employed to calculate the Oral Reference Dose in the IRIS Ba File is 0.21 mg/kg/day; there is no LOAEL associated with this NOAEL. The NOAEL reported in 62 FR 366-372 is 70 mg/kg/day in rats and 165 mg/kg/day in mice; these values are taken from a National Toxicology Program technical report and are associated with a LOAEL of 180 mg/kg/day. -
Acetal (POM) Chemical Compatibility Chart From
ver 31-Mar-2020 Acetal (POM) Chemical Compatibility Chart Chemical Chemical Acetaldehyde A Ammonium Acetate C Acetamide A Ammonium Bifluoride D Acetate Solvents A Ammonium Carbonate D Acetic Acid D Ammonium Caseinate D Acetic Acid, 20% C Ammonium Chloride, 10% B Acetic Acid, 80% D Ammonium Hydroxide D Acetic Acid, Glacial D Ammonium Nitrate, 10% A Acetic Anhydride D Ammonium Oxalate B Acetone A Ammonium Persulfate D Acetyl Chloride, dry D Ammonium Phosphate, Dibasic B Acetylene A Ammonium Phosphate, Monobasic B Alcohols: Amyl A Ammonium Phosphate, Tribasic B Alcohols: Benzyl A Ammonium Sulfate B Alcohols: Butyl A Ammonium Sulfite D Alcohols: Diacetone A Ammonium Thiosulfate B Alcohols: Ethyl A Amyl Acetate B Alcohols: Hexyl A Amyl Alcohol A Alcohols: Isobutyl A Amyl Chloride A Alcohols: Isopropyl A Aniline A Alcohols: Methyl A Aniline Oil D Alcohols: Octyl A Anise Oil D Alcohols: Propyl (1-Propanol) A Antifreeze D Aluminum chloride, 20% C Aqua Regia (80% HCl, 20% HNO3) D Aluminum Fluoride C Aromatic Hydrocarbons A Aluminum Hydroxide A Arsenic Acid D Aluminum Nitrate B Asphalt B Aluminum Potassium Sulfate, 10% C Barium Carbonate A Aluminum Potassium Sulfate, 100% C Barium Chloride A Aluminum Sulfate, 10% B Barium Cyanide B Alums C Barium Hydroxide D Amines D Barium Nitrate B Ammonia, 10% (Ammonium Hydroxide) C Barium Sulfate B Ammonia, 10% D Barium Sulfide A Ammonia, anhydrous D Bay Oil D Ammonia, liquid D Beer A Ammonia Nitrate C Beet Sugar Liquids B Key to General Chemical Resistance – All data is based on ambient or room temperature conditions, about 64°F (18°C) to 73°F (23°C) A = Excellent C = Fair - Moderate Effect, not recommended B= Good - Minor Effect, slight corrosion or discoloration D = Severe Effect, not recommended for ANY use It is the sole responsibility of the system designer and user to select products suitable for their specific application requirements and to ensure proper installation, operation, and maintenance of these products. -
MS32-Chun-Red
Text19/12/2008 MATERIAL SAFETY DATA SHEET PRODUCT / MATERIAL: GLAZE MANUFACTURER / DISTRIBUTOR: LAGUNA CLAY COMPANY ADDRESS: 14400 Lomitas Avenue, City of Industry, CA 91746 PHONE / FAX / EMAIL: (626) 330-0631 / (626) 333-7694 / [email protected] SECTION I - PRODUCT INFORMATION TRADE NAME: MS32 SYNONYM: CHUN RED CHEMICAL FAMILY: Ceramic Blend SECTION II - HAZARDOUS INGREDIENTS Maximum OSHA PEL NIOSH REL ACGIH TLV INGREDIENT NAMEPercent CAS NUMBER TWA: (mg/m3) TWA: (mg/m3) TWA: (mg/m3) Barium or Barium Compounds5 7440-39-3 0.5 0.5 0.5 Calcium Carbonate7 1317-65-3 5 5 10 Lithium Carbonate1 554-13-2 Silica, Crystalline (Quartz)20 14808-60-7 10 mg/m3 / 0.05 0.05 %SiO2 + 2 Silicon Carbide1 409-21-2 15 10 Tin or Tin Compounds2 7440-31-5 2 2 Zinc or Zinc Compounds4 7440-66-6 5 5 5 SECTION III - PHYSICAL DATA BOILING POINT (°F) Not Applicable VAPOR PRESSURE Not Applicable VAPOR DENSITY Not Applicable SOLUBILITY IN WATER Insoluble SPECIFIC GRAVITY 1.7 – 3.7 PERCENT VOLATILE BY WEIGHT 0 EVAPORATION RATE 0 APPEARANCE AND ODOR Color varies between moist and dry state; no odor. SECTION IV - FIRE AND EXPLOSION HAZARD DATA FLASH POINT Not Flammable EXTINGUISHING MEDIA Water UNUSUAL FIRE OR EXPLOSION HAZARDS None SPECIAL FIRE FIGHTING PROCEDURES None SECTION V - REACTIVITY DATA STABILITY FACTOR Product is stable. INCOMPATIBILITY None HAZARDOUS DECOMPOSITION PRODUCTS None. Hazardous polymerization will not occur. CONDITIONS TO AVOID Inhalation of dust. Text10MS32 Text10Page 1 of 3 Text19/12/2008 MATERIAL SAFETY DATA SHEET SECTION VI - HEALTH HAZARD DATA Barium or Barium Compounds Chronic Toxicity: Chronic overexposure may lead to varying degress of paralysis of the extremities. -
Chemical Resistance of NYCAST Materials
Chemical Resistance of NYCAST Materials Distributed by: Chemical Temp.0C conc.% rating Chemical Temp.0C conc.% rating ACETALDEHYDE 23 40 A BARIUM HYDROXIDE 23 100 G ACETAMIDE 23 50 G BARIUM NITRATE 23 100 G ACETC ACID 100 2 G BARIUM SULFATE 23 15 G ACETIC ACID 100 10 P BARIUM SULFIDE 23 100 G ACETIC ACID 23 2 G BEER 23 100 G ACETIC ACID 23 10 P BEET LIQUIDS 23 100 H ACETICANHYDRIDE 23 100 P BENZALDEHYDE 23 100 P ACETONE 23 100 G BENZALDEHYDE 23 0.3 G ACETONITRILE 23 100 G BENZENE 23 100 G ACETYL CHLORIDE 23 100 P BENZOIC ACID 23 100 P ACETYLENE 23 100 G BENZYL ALCOHOL 23 100 Q ACRYLONITRILE 23 100 G BENZVL CHLORIDE 23 100 G ALLYLALCOHOL 23 100 A BORAX 23 SAT G ALLYL CHLORIDE 23 100 G BORIC ACID 23 10 A ALUM 23 SAT A BRANDY 23 100 G ALUMINUM CHLORIDE 23 10 G BROMINE 23 100 Q ALUMINUM FLUORIDE 23 100 G BROMINE 23 10 Q ALUMINUM HYDROXIDE 23 100 G BUTANE 23 100 G ALUMINUM POTASSIUMSULPHATE 23 10 P BUTANOL 23 100 G ALUMINUM SULFATE 50 10 G BUTTER 23 100 G AMMONIA 23 10 G BUTIER MILK 23 100 G AMMONIA 100 10 G BUTYL ACETATE 23 100 G AMMONIUM ACETATE 23 100 G BUTYLENE 23 100 A AMMONIUM CARBONATE 23 100 G BUTYLENE GLYCOL 23 100 G AMMONIUM CHLORIDE 23 10 G BUTYRIC ACID 23 100 A AMMONIUM CHLORIDE 23 37 G CALCIUM BISULFIDE 23 100 G AMMONIUM FLUORIDE 23 100 G CALCIUM BISULFITE 50 100 G AMMONIUM HYDROXIDE 23 40 G CALCIUM CARBONATE 23 100 G AMMONIUM NITRATE 23 100 G CALCIUM CHLORIDE 23 SAT Q AMMONIUM PERSULFATE 23 100 Q CALCIUM CHLORIDE 100 SAT P AMMONIUM PHOSPHATE 23 100 G CALCIUM HYDROXIDE 50 100 G AMMONIUM SULPHATE 23 100 G CALCIUM HYPOCHLORITE 23 -
Federal Law and Vertebrate Pest Control
University of Nebraska - Lincoln DigitalCommons@University of Nebraska - Lincoln Proceedings of the 1st Vertebrate Pest Vertebrate Pest Conference Proceedings Conference (1962) collection February 1962 FEDERAL LAW AND VERTEBRATE PEST CONTROL Justus C. Ward Director, Pesticides Regulation Division, Agricultural Research Service, U.S. Department of Agriculture Follow this and additional works at: https://digitalcommons.unl.edu/vpcone Part of the Environmental Health and Protection Commons Ward, Justus C., "FEDERAL LAW AND VERTEBRATE PEST CONTROL" (1962). Proceedings of the 1st Vertebrate Pest Conference (1962). 25. https://digitalcommons.unl.edu/vpcone/25 This Article is brought to you for free and open access by the Vertebrate Pest Conference Proceedings collection at DigitalCommons@University of Nebraska - Lincoln. It has been accepted for inclusion in Proceedings of the 1st Vertebrate Pest Conference (1962) by an authorized administrator of DigitalCommons@University of Nebraska - Lincoln. FEDERAL LAW AND VERTEBRATE PEST CONTROL By: Justus C. Ward, Director, Pesticides Regulation Division, Agricultural Research Service, U.S. Department of Agriculture Presented at the Vertebrate Pest Control Conference, Sacramento, California, February 6 and 7, 1 962 Shortly after the passage of the Federal Insecticide Act of 1910> mammal control specialists in the Bureau of Biological Survey began to consider a similar law to cover the chemicals with which they were concerned. Work on the project went slowly a nd spasmodically, but reached the point of having a Federal Rodenticide Act available for study and possible revision in 1928. At this time, the mammal control chemicals in use were limited to strychnine -- alkaloid and sulphate -arsenic, barium carbonate, th allium sulphate, phosphorus, s odium and calcium cyanide, carbon disulphide, and red squill. -
An Approach to Interpreting Restrictive Spirometric Pattern Results In
Med Lav 2016; 107, 6: 419-436 An approach to interpreting restrictive spirometric pattern results in occupational settings Federica Tafuro, Massimo Corradi Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy KEY WORDS Diagnostic algorithm; FEV1; FVC; FEV6; FEV1/FVC; interpretative criteria; lung function testing; occupa- tional exposure PAROLE CHIAVE Algoritmi diagnostici; FEV1; FVC; FEV6; FEV1/FVC; criteri interpretativi; test di funzionalità polmonare; esposizione occupazionale SUMMARY Objectives: The aim of this review is to provide an updated overview of definition, epidemiology, diagnostic algo- rithm and occupational exposures related to abnormal restrictive spirometrical pattern (RSP) in order to improve the correct interpretation of spirometry test results by occupational healthcare providers. Methods: A review of the scien- tific English literature of the last 25 years was carried out with MEDLINE and related keywords [(restricti* AND spirometr*) AND occupational]. The first step analysis covered 40 studies and the second step the reference list. Results are presented in four major aims and subquestions. Results: A spirometrical pattern of reduced VC (Vital Capacity), together with a normal FEV1 (Forced Expiratory Volume in 1 Second)/VC ratio, is suggestive, though not diagnostic of restrictive ventilatory defect (RVD). The prevalence of RSP is high in some studies, comparable to obstructive pat- tern, and could be associated to chronic medical conditions (diabetes, congestive heart failure, obesity, hypertension) as well as to increased risk of mortality and lung cancer. In order to predict true restrictive defect [TLC-(Total Lung Capacity) <LLN (Lower Limit of Normality) gold-standard for diagnosing restrictive lung diseases (RLD)] from spirometrical data, mathematical models have been developed, but more studies in occupational setting are necessary to clarify the accuracy of such approaches in health surveillance programmes.