SFRR-I 2021 20Th Biennial Meeting of SFRR International
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Online Congress Scientific 15–18 March 2021 Program 20th Biennial Meeting of SFRR International SFRR-I 2021 sfrri2021.com Agenda Monday Scientific 15 March 2021 Program Time (CET) Channel 1 Channel 2 08.45 – 09.00 Opening Ceremony Giovanni E. Man, Juan Sastre & José Viña 09.00 – 11.00 Symposium 1 Relevance of Oxygen Levels for Stem Cell Redox Biology and Regenerative Medicine Chairs: Giovanni E. Mann King’s British Heart Foundation Centre of Excellence, Faculty of Life Sciences & Medicine, King’s College London, London, UK José Viña Freshage Research Group Department of Physiology. University of Valencia, Spain Cellular redox signaling under physiological normoxia and ischemia- reperfusion Giovanni E. Mann King’s British Heart Foundation Centre of Excellence, Faculty of Life Sciences & Medicine, King’s College London, London, UK Transcriptomic and proteomic characterization of human cardiac progenitor cells Maria J. Sebastião Animal Cell Technology Unit, iBET Instituto de Biologia Experimental e Tecnológica, Portugal Relevance of oxygen concentration in stem cell culture for regenerative medicine Consuelo Borras Freshage Research Group- Department of Physiology, Faculty of Medicine, University of Valencia, Valencia, Spain Do hypoxia mimetic agents’ provide fidelity in replication of engineered oxygen control measures in human mesenchymal stem cell isolation and culture? Nicholas R. Forsyth School of Pharmacy and Bioengineering, Keele University Break 30 min Agenda Monday Scientific 15 March 2021 Program Time (CET) Channel 1 Channel 2 11.30 – 12.30 Trevor Slater Award Lecture Chairs: Daniela Caporossi University of Rome Foro Italico. Rome. Italy José Viña Freshage Research Group Department of Physiology. University of Valencia. Spain A redox-centred view of skeletal muscle responses to exercise and ageing Malcolm Jackson Institute of Ageing and Chronic Disease, University of Liverpool, UK 12.30 – 13.30 Oral Comunications 1 Narrated Communications Chairs: Nesrin Kartal-Özer Chairs: Corinne Spickett Department of Biochemistry. Biosciences Research Group. Faculty of Medicine. Marmara Aston University. UK University. Istanbul. Turkey Osamu Handa Lars Oliver-Klotz Department of Gastroenterology Institute of Nutritional Sciences. and Hepatology. Kyoto Prefectural Jena. Germany University of Medicine OP1 – OP4 Discussion Session 1 NC1 – NC11 Break 1 hour 14.30 – 16.00 Narrated Communications Narrated Communications Chairs: Pablo Evelson Chairs: Patricia Oteiza Universidad de Buenos Aires. University of California Davis. Davis. Facultad de Farmacia y USA Bioquímica. Departamento de Química Analítica y Fisicoquímica. Francisco Laurindo Cátedra de Química General Vascular Biology Laboratory. e Inorgánica. Buenos Aires. University of São Paulo Argentina. CONICET - Universidad de Buenos Aires. Instituto de Bioquímica y Medicina Molecular Discussion Session 3 (IBIMOL). Buenos Aires. Argentina. NC30 – NC44 Christian González Departamento de Biología. University of Chile Discussion Session 2 NC12 – NC29 Agenda Monday Scientific 15 March 2021 Program Time (CET) Channel 1 Channel 2 16.00 – 18.00 Symposium 2 Symposium 3 Precision Redox and Mitochondrial Revising Redox Biology: New insights from Quality in Aging Selenium Chair: Chang Chen Chairs: Xingen Lei Institute of Biophysics, Chinese Cornell University, USA Academy of Sciences, Beijing, China Yongping Bao University of East Anglia, UK Redox-stress response capacity decline and ER reductive stress in aging New functions of selenoproteins: beyond Chang Chen redox reactivity Institute of Biophysics, Chinese Academy Xingen Lei of Sciences, Beijing, China Cornell University, USA Relative importance of human and mouse Mitochondrial H2O2: new insights from selenoproteins imaging Vadim Gladyshev Vsevolod Belousov Brigham and Women’s Hospital, Harvard Department of Metabolism and Redox Medical School, Boston, USA Biology, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russia The molecular underpinnings of selenium in ferroptosis Mitochondrial transport and energy Marcus Conrad homeostasis in neuronal degeneration Institute of Developmental Genetics, and regeneration Helmholtz Zentrum München, Germany Zu-Hang Sheng Synaptic Function Section, NINDS, NIH, USA The selenoprotein thioredoxin reductase 1 (TrxR1, TXNRD1) as a main regulator of growth Age and sex determine the effectiveness factor responses of redox adaptive homeostasis Elias Arnér Kelvin J. A. Davies Department of Medical Biochemistry and Leonard Davis School of Gerontology Biophysics (MBB). Karolinska Institutet, of the Ethel Percy Andrus Gerontology Stockholm, Sweden Center, University of Southern California, Los Angeles, USA 18.00 – 18.30 SFRR-I Executive Committee Meeting Agenda Tuesday Scientific 16 March 2021 Program Time (CET) Channel 1 Channel 2 09.00 – 11.00 Symposium 4 Role of Redox-active Metals for the Prevention and Treatment of Cancer in the Era of Precision Medicine Chairs: Shinya Toyokuni Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, Japan Des R. Richardson Pathology and Bosch Institute, University of Sydney, Australasia Role of ferroptosis in carcinogenesis and tumor biology Shinya Toyokuni Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, Japan Targeting cellular signalling to inhibit tumour cell metastasis and growth: The iron and NDRG1 connection Des R. Richardson Pathology and Bosch Institute, University of Sydney, Australasia Anticancer platinum and gold compounds with thiol-targeting mechanisms of action Chun-Nam Lok Department of Chemistry and Chemical Biology Center, The University of Hong Kong, Hong Kong Nanochelator of iron for improved iron removal efficacy in various disease models Guangjun Nie National Center for Nanoscience and Technology, China Break 30 min Agenda Tuesday Scientific 16 March 2021 Program Time (CET) Channel 1 Channel 2 11.30 – 12.30 Oral Comunications 2 Oral Comunications 3 Chairs: María Monsalve Chairs: Tilman Grune Institute of Biomedical Research Department of Physiological “Alberto Sols”. CSIC-UAM. Madrid. Chemistry and Cellular Spain Biochemistry. Faculty of Chemistry. University of Vienna Fabio Virgili Centro Ricerche Alimenti e Clare L. Hawkins Nutrizione. Consiglio Nazionale Department of Biomedical per la Ricerca e Sperimentazione Sciences. University of in Agricoltura e l’Economia Copenhagen. Copenhagen. Agraria. Roma Denmark OP5 – OP8 OP9 – OP12 Break 1 hour 13.30 – 15.00 Narrated Communications Narrated Communications Chairs: Giuseppe Valacchi Chairs: Henry Forman Dep.t of Neuroscience and Leonard Davis School of Rehabilitation. University of Gerontology. Los Angeles. CA Ferrara. Ferrara. Italy. Joao Laranjinha Florian Gruber Center for Neurosciences and Department of Dermatology. Cell Biology. Faculty of Pharmacy. Medical University of Vienna University of Coimbra. Portugal Discussion Session 4 Discussion Session 5 NC45 – NC63 NC64 – NC81 15.00 – 16.00 Keynote Lecture I A mitochondrial etiology of complex diseases Douglas Wallace The Center for Mitochondrial and Epigenomic Medicine at Children’s Hospital of Philadelphia, Philadelphia, USA Agenda Tuesday Scientific 16 March 2021 Program Time (CET) Channel 1 Channel 2 16.00 – 18.00 Symposium 5 Symposium 6 Redox Regulation of the Epigenetic Nutrition and redox signaling Landscape Chairs: Cesar Fraga Chair: Frederick Domann Fisicoquímica, Facultad University of Iowa, USA de Farmaciay Bioquímica, Universidad de Buenos Aires (UBA); and Instituto de Epigenetics, the third pillar of nitric oxide Bioquímicay Medicina Molecular signalling (IBIMOL), UBA-CONICET, Buenos Douglas Thomas Aires, Argentina. Pharmaceutical Sciences, University of Illinois at Chicago, USA José Viña Freshage Research Group Redox-dependent regulation of Department of Physiology. chromatin methylation University of Valencia, Spain Alison Brewer Department of Cardiology, King’s College London, UK Relevance and bioactivity of flavonoids as regulators of redox signalling Regulation of labile Fe(II) and further DNA/ Cesar Fraga histone demethylation by cAMP signaling Fisicoquímica, Facultad de Farmaciay Gaofeng Wang Bioquímica, Universidad de Buenos Aires Department of Human Genetics, (UBA); and Instituto de Bioquímicay University of Miami Miller School of Medicina Molecular (IBIMOL), UBA-CONICET, Medicine, USA Buenos Aires, Argentina. Maternal exposure to a mitochondrial Exercise as an antioxidant supplement to toxicant results in life-long alterations in promote healthy ageing and delay frailty the epigenetic landscape of the offspring José Viña Janine Santos Freshage Research Group Department of National Institutes of Health, USA Physiology. University of Valencia, Spain Ketogenic diets, nutrient signaling and mitochondria Jon Ramsey Veterinary Medicine Department of Molecular Biosciences, University of California, USA Zinc and redox signaling: impact on brain development and function Patricia Oteiza Departments of Nutrition and of Environmental Toxicology, University of California, Davis, USA Agenda Wednesday Scientific 17 March 2021 Program Time (CET) Channel 1 Channel 2 09.00 – 11.00 Symposium 7 Symposium 8 Redox regulation: Thiols, novel roles and Regulation of Redox Signaling by Nrf2 in novel thiols Health and Disease Chair: Ivan Gout Chair: Young-Joon Surh Department of Structural and Tumor Microenvironment Global Molecular Biology, University Core Research Center, Seoul College London, UK National University, Korea Ergothioneine, a thiol/thione antioxidant