MEDICAL RESEARCH FOUNDATION OLD NO.18, NEW NO.41, COLLEGE ROAD, CHENNAI 600 006

ANNUAL REPORT & ACCOUNTS 2015 - 2016

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To The Members of the Medical Research Foundation 29th August 2016

NOTICE

NOTICE IS HEREBY GIVEN TO THE MEMBERS OF THE MEDICAL RESEARCH FOUNDATION THAT THE 38TH ANNUAL GENERAL MEETING OF THE FOUNDATION WILL BE HELD ON SATURDAY, THE 24th SEPTEMBER 2016 AT 5.00 P.M. AT BOARD ROOM, 2ND FLOOR, KAMALNAYAN BAJAJ RESEARCH CENTRE BLOCK, NEW NO 41, OLD NO 18, COLLEGE ROAD, CHENNAI 600 006.

AGENDA 1. To consider and adopt the Audited Income and Expenditure Account for the year ended March 31, 2016 and the Balance Sheet as at that date together with the Report of the Auditors thereon.

2. To consider and adopt the Annual report of the Foundation for the year 2015-16.

3. To appoint Auditors and to fix their remuneration for the year ending 31st March 2017.

4. To elect Members to the Board of Management in the vacancies caused by the retirement of the following Members, who being eligible offer themselves for re-appointment

Sl. No Name Category of Membership 1 Mr. C. Ramakrishna Founder member 2 Dr. M. Saravanan Donor member 3 Mr. V. Govind Donor member 4 Mr. N. Ranganatha Gupta Donor member 5 Mr. Surendra M Mehta Donor member 6 Mr. N. Sugalchand Jain Donor member 7 Mr. R.C. Parekh Donor member 8 Dr. Usha Barwale Zehr Donor member 9 Mr. G. Ramachandran Donor member 10 Dr. S. S. Badrinath Honorary member 11 Dr. T. S. Surendran Honorary member 12 Dr. Lingam Gopal Honorary member

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Sl. No Name Category of Membership 13 Dr. K. S. Vasan Honorary member 14 Dr. Pramod S. Bhende Honorary member 15 Mr. N. D. J. Renganath Honorary member 16 Mr. Raju Barwale Patron member 17 Mr. Jagdish M. Chanrai Patron member 18 Ms. Prabhavathy Seethapathy Patron member

5. To elect Members to the Board of Management in the existing vacancy.

Kindly make it convenient to attend the meeting.

G. RAMACHANDRAN Honorary Secretary Encl: 1. Explanatory statement for Item 4 of the Agenda 2. Audited Accounts for the year ended March 31, 2016

Explanatory statement for Item 4 of the Agenda

Their term of appointment expires on 29th September 2016. As per 11(v) of the Bye-laws of the Foundation read with Section 15(5) of the Tamil Nadu Societies Registration Act 1975, they are eligible for reappointment to the Board of Management. They have offered themselves for reappointment.

As per bye laws of the Foundation 10(d) Mr. Raju Barwale being the nominee member of the M/s Keligavan Investment and Trading Private Limited is automatically entitled to be re-elected on completion of three years.

As per bye laws of the Foundation 10(d) Mr. Jagdish M. Chanrai being the nominee member of the M/s Jaslok Hospital and Research Center is automatically entitled to be re-elected on completion of three years.

G. RAMACHANDRAN Honorary Secretary

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SANKARA NETHRALAYA

MISSION STATEMENT QUALITY OBJECTIVES

The mission of Sankara Nethralaya is to To maintain the quality of ophthalmic provide Total Eye-care solutions of highest s e r v i c e s i n a c c o r d a n c e w i t h standards to all sections of community international standards. through a team of competent, committed and compassionate professionals in a patient- Effective utilization of infrastructure friendly environment. facilities including manpower.

Sankara Nethralaya is also committed to To ensure continued patients' create a CENTRE of Excellence for ophthalmic satisfaction. professionals for continuously updating their To ensure high level of staff satisfaction knowledge through Education, Training, and and motivation. carrying innovative India centric Research to benefit the entire ophthalmic community.

In all our undertakings we will be guided by the underlying philosophy of Sankara Nethralaya.

PHILOSOPHY QUALITY POLICY

Let the word Sankara of Sankara Nethralaya We pledge to meet the patients' requirements ever remind me and my associates His by offering expert ophthalmic care with Holiness' command that there be a missionary c om p a s s i on th rou g h a c om m i tte d Spirit in the project. professional team.

Let the word Nethralaya constantly remind We commit to achieve quality services me and my colleagues that the place of our through the Quality Management System work is an Alaya. Work will be our Worship while complying with all applicable which we shall do with sincerity, dedication regulatory requirements. and utmost Love.

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BOARD OF MANAGEMENT 2015 - 2016

President Dr. S. S. Badrinath

Honorary Secretary Mr. G. Ramachandran

Honorary Treasurer Mr. N. Sugalchand Jain Other Members of the Board

1. Mr. Ashok Kumar Mehta Member 2. Dr. Barwale B. R Member 3. Mr. Govind V Member 4. Mr. Jagdish M. Chanrai Member 5. Dr. Lingam Gopal Member 6. Mrs. Mallika Srinivasan Member 7. Mr. Mani S. Subramonian Member 8. Mrs. Nina B. H. Kothari Member 9. Mr. Parekh R. C Member 10. Ms. Prabhavathy Seethapathy Member 11. Dr. Pramod S. Bhende Member 12. Dr. Prema Padmanabhan Member 13. Mr. Ramakrishna C Member 14. Dr. Ramasami T Member 15. Mr. Rajaratnam S Member 16. Ms. Rajashree Birla Member 17. Mr. Raju Barwale Member 18. Mr. N. Ranganatha Gupta Member 19. Mr. Renganath N. D. J Member 20. Dr. Surendran T. S Member 21. Dr. Saravanan M Member 22. Mr. Surendra M. Mehta Member 23. Mr. Taraporevala B. S Member 24. Dr. Usha Zehr Barwale Member 25. Mr. Vaidyanathan V Member 26. Dr. Vasan K. S Member

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Managing Director : Dr. K. S. Vasan

Senior General Manager : Ms. Akila Ganesan

Deputy General Manager (Finance) : Ms. Susila Girisan

Auditors : M/s. S. Viswanathan, LLP Chartered Accountants, Chennai

Bankers : HDFC Bank Ltd., State Bank of India

Registered Office : Old No.18, New No.41, College Road, Chennai - 600 006. Locations of Sankara Nethralaya:

Tamil Nadu Andra Pradesh

Main Hospital Sri Srinivasa Sankara Nethralaya Old No.18, New No.41, College Road, Chennai-600006. Central Hospital, K.T. Road (Near TTD Administration Bldg.) Tirupathi 517 501. Jagadguru Kanchi Sri Chandrasekarendra Saraswathi Nethra Nilayam Sri City Sankara Nethralaya 21, Pycrofts Garden Road, Chennai 600 006. (A Unit of Medical Research Foundation, Chennai) Sri City Medical Care Center,305, North, 2nd street, Sector3, Dr. V. G. Appukutty Campus, Sri City, Varadaiahpalem Mandal, Elite School of Optometry & Chittoor Dist, AP - 517541. C.U. Shah Sankara Nethralaya No.8, GST Road, St. Thomas Mount, Chennai 600 016. West Bengal

Navasuja Sankara Nethralaya Aditya Birla Sankara Nethralaya No.73, VenkataKrishna Iyer Road, No.147, Barakhola, Mukundapur, E M Bypass, (Near Raja Annamalaipuram, Chennai 600028. Santhoshpur Connector Kolkata - 700 099.

Jaslok Community Ophthalmic Centre Sankara Nethralaya RSM Square 138, Rama Building ,Greams Road, Chennai 600 006. No.10, Raja Subodh Mallik Square Kolkata - 700013 Smt. T. K. Lakshmi Ammal and Smt. T.K. Sankara Nethralaya Lasik Centre Alamelu Ammal Sankara Nethralaya No 41, AJC Bose Road, Diamond Prestige Complex, New No 39. Old no. 19, 1st Main Road, Kolkata – 700 017. East Shenoy Nagar, Chennai 600 030.

The Sankara Nethralaya Academy - Vanagaram No 9, Vanagaram Road, Ayanambakkam, Chennai 600 095.

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ANNUAL REPORT FOR THE FINANCIAL YEAR 2015-16

I have great pleasure in presenting the 38th Annual Report of the Medical Research Foundation.

FINANCIAL PERFORMANCE

The financial performance of the Foundation for the year 2015-16 is summarized below:

(Rs in Lakhs)

Description 2015-16 2014-15

INCOME

Hospital Collections 15974 14460

Grants and Other Income 3248 1707

Total Income 19222 16167

EXPENDITURE 15651 14023

Surplus before Depreciation 3571 2144

Depreciation 1116 1149

Net Surplus 2474 1028

The Hospital Collection this year was higher by Rs.1514 lakhs compared to 2014-2015 with an increase of 10%. After meeting all the expenses including depreciation Net Income over Expenditure was Rs.2474 lakhs compared to the Net Income over Expenditure of Rs.1028 lakhs of 2014-15.

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CASH FLOW (Rs in Lakhs)

Description 2015-16 2014-15

Source

Cash flow from operations 2474 2144 Donations 1091 1945 NRTT Liability 446 Increase / Decrease In Current Liabilities 215 117 Total Sources 4226 4206

Applications Investment - Capital expenditure 379 245 Investment - Project (SNC&SNK) 2515 1654 Investment - Esoor Land - 671 Deferred credit towards Capex 189 170 Investment - RBI Bonds 144 147 Investment - Fixed Deposits 1638 ICICI Technology loan - Repayment 500 - NRTT Advance payments 107 - Increase/Decrease in Current Asset 392 (319) Total Applications 4226 4206 Total Applications 4206 6392 Donations Donations received during the year amounted to Rs.1091 lakhs. The corresponding figures for 2014-15 were Rs.1945 lakhs. Out of total Donations, donation received towards corpus during the year amounted to Rs. 136 lakhs, towards projects A Sivasilam Block Rs.280 lakhs and other donations during the year amounted to Rs. 675 lakhs. Fixed Assets Additions amount to Rs.379 lakhs which Equipments for updating of technology and replacements. Rs.2515 lakhs spent towards new project in SN Chennai and SN Kolkata. Investments Corpus fund Investments in RBI Bonds and Fixed Deposits as at 31st March 2016 is Rs.3815 lakhs compared to Rs. 3732 lakhs as at 31st March 2015.

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OPERATIONAL PERFORMANCE

DESCRIPTION NUMBERS YEAR 2015-16 2014-15

OUTPATIENT CONSULTATION 679965 651423

MAJOR OUTPATIENT PROCEDURE 97336 90662

SURGICAL PROCEDURE 55100 52935

Treatment of Poor Patients The number of free surgeries in the FY 2015-16 was 19107 against 18531in FY 2014-15. Number of free surgeries as a percentage of total surgeries done was 35%in the FY 2015-16 as well as in the FY 2014-15. The revenue foregone through free services and waiver / concessions amounts to Rs.3560 Lakhs. Last year the corresponding amount was Rs.3267 lakhs.

DEPARTMENT ACTIVITIES The Details of Corneal Transplant services during the period April 2015 – March 2016 are as follows: 1. Total Number of eyes Collected: 1251 numbers 2. Total Number of Corneal Transplant surgeries performed: 624 No's 3. Amount Received from Reliance Dhristi Project towards performance of free corneal transplant: Rs. 5,58,000 (Rs. Five Lakh and fifty eight Thousand only)

PRABHA ENDOWMENT Ms. Prabha, Chief Executive Officer and Managing Director of M/s Petro Star Corporation LLC,had donated Rs. 50 lakhs last year to create a Corpus for treatment of patients suffering from Ocular surface Disease. This corpus fund is being maintained as a separate fund named as “Prabha Endowment Fund.”This year 16 patients have been benefited through this endowment and an amount of Rs. 5.00 lakhs has been utilised towards treatment costs for the said patients.

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QUALITY INITIATIVES Sankara Nethralaya MAIN Campus: · All patient complaints are analyzed every week and taken up to the concerned Head of the Department · Staff of SN appreciated by the patient are acknowledged in the SN portal & an email is sent to respective staff appreciating the dedicated service · Latest 4th edition of NABH standards are under the process of implementation · NABH core team is formed to implement the new standards and training is under process · Quality indicators are revised and benchmarks are evaluated for few Departments

H T Parekh Campus: · Surveillance audit is expected in September · Latest 4th edition of NABH standards are under the process of implementation · Quality indicators are revised and benchmarks are evaluated for few Departments · NABH core team is formed to implement the new standards and training is under process · Quality indicators are revised and benchmarks are evaluated for few Departments

CU SHAH Sankara Nethralaya (CUSSN): · Implemented latest SHCO 2nd Ed Standards of NABH. · NABH final Assessment was conducted during March 2016.

Navasuja Sankara Nethralaya (NSN): · Implemented latest SHCO 2nd Ed Standards of NABH

IT & Systems IT is now a strategic part of the SN operations. Various initiatives had been launched to maximize the impact of IT for day to day operations and also for improved patient care. Newer modules had been developed to support MESU and Telemedicine. Billing services now include patients covered under CGHS Intelligent alerts built to track for special precaution patients to enable relevant support for surgery scheduling and related services Automated alerts through SMS for patients for various transactions and activities from HMS/ EMR Enabling patients to fill up personal details online for faster admission process Sustained enhancements to EMR to improve ease of use and functional enhancements. Enhancements to reporting capabilities for improved decision making

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From an IT infrastructure perspective continued to modernize the solution architecture which enables and guarantees better security & predictability of our digital assets.

The implementation of Ophthalmic EMR has been well accepted across the country. With new implementations at Lotus Eye Hospital and additions to Eye Q Hospitals now the total installations across the country is at 102 and many of them are the tier 2 and tier 3 towns / locations, which speaks volumes of the maturity of the processes and its universal acceptability across the users. FUND RAISING ACTIVITIES

V.G.P. Ravidas and fellow Rotarians present the proceeds of the 'Terry Fox Run' to Dr. Vikas Khetan towards supporting research in Retinoblastoma

A large gathering assembled at the IIT-Madras campus for the 'Terry Fox Run'

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Sankara Nethralaya employees create awareness on retinoblastoma at the Terry Fox Run The Terry Fox Foundation the Canada based body espousing the cause of its illustrious champion against cancer, Terrance Stanley Fox conducts the 'Terry fox Run- A Marathon of hope' the world over to raise funds for cancer research and treatment. This year the Terry Fox Run proceeds were handed over to Dr. S. S. Badrinath, Chairman Emeritus by Shri. V. G. P. Ravidas, President and Shri Badrinarayanan, Chairman, Rotary Club of Madras East. Expressing his sincere thanks Dr. S. S. Badrinath mentioned that researchers are hopeful of identifying critical biomarkers for early diagnosis of retinoblastoma. The House of GRT and its founder Shri G. Rajendran have been long time friends and supporters of Sankara Nethralaya. The leading jeweler joined hands with the local chapters of Lions Club, Rotary Club, Catholic Society of Canada and the Tiruvallur District Blindness Control Society and Sankara Nethralaya to conduct a comprehensive eye screening/surgical camp deploying the Mobile Eye Surgical Unit (MESU). A total of 796 local people were screened and high quality cataract removal surgery, followed by implantation of intra-ocular lens was carried out and vision was revived for 155 patients.

Delivering the Chief Guest's address during the valedictory function, Shri K.Veera Raghava Rao, IAS, Collector of Tiruvallur observed that he considered it an honour to be a part of such a noble initiative and thanked the organizers for the same.

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Mobile Eye Surgical Unit Camp at Tiruttani sponsored by the house of GRT Life and achievements of a long time friend of Sankara Nethralaya, dynamic SN OM Trustee Mr. Sam Kannappan and wife were chronicled into Houston's glorious history by Texas based 'The Foundation For India studies' (FIS) dedicated to the objective of highlighting and promoting India's contribution to the world in the field of languages, literature, arts, sciences, engineering, politics, economics and spirituality. Shri Sam Kannappan and his wife Shrimathi Kannappan among the most prominent, versatile and multifaceted early Indian settlers with a glorious record of contributing both to their motherland and their country of adoption and to fellow American Indians were interviewed as part of this project. We thank the following donors for their continuous support for our community service: S.No Title NAME 1 M/s Tafe Foundation 2 M/s Indian Coal Agency 3 M/s Prestige Foundation 4 M/s Krishna Antioxidants Pvt Ltd 5 M/s Sobha Developers Ltd 6 M/s Blue Cross Laboratories Ltd 7 M/s Sikkim Jansewa Pratisthan Pvt Ltd 8 M/s Indian Bank

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HUMAN RESOURCES DEVELOPMENT The Employee's strength as on 31st March 2016 was 1300 (31st March 2015 – 1225) Particulars As on 31.03.2016 As on 31.03.2015 Consultants * 133 116 Executives & Optometrists 413 389 Staff 754 720 TOTAL 1300 1225 *Includes Ophthalmologists, Physicians and Anesthetists

The Department of Human Resource believes in boosting the morale of the employees with its effective and competent organizational practices, thereby maximizing employee performance levels and efficiency in the Institution. Through its employee engagement and welfare programs, the department has constantly been motivating and enriching the employee's career progress. The employees are also encouraged to go for higher studies and increase their personal efficiency. Sankara Nethralaya has always believed in recognizing the performance of employees through its Recognition programs. The best Man & Woman employee of the year, the best Department and the Outstanding performers in each department are chosen and rewarded at the Independence Day celebrations held every year. Hard work and dedication of employees is also recognised by honouring the number of years of service in Sankara Nethralaya.

Shri. A.Padmanabhan, Head, Transport Department receives the 'Man of the Year' Award from Justice S.Jagadeesan

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Ms Sunita Sarkar Optometry Admin in-charge was awarded the 'Woman of the Year'2015-16 Mr. Padmanabhan A of Transport Department and Ms. Sunita Sarkar of Optometry Department, Sankara Nethralaya, Kolkata were adjudged the Man and Woman of the year 2015.

Dr. Sheila John, HOD Multimedia dept receives the 'Best Department' award with her colleagues

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The Multimedia Department was adjudged the Best Department of Sankara Nethralaya for the year 2015. The CU Shah Sankara Nethralaya team was chosen for a special award of recognition for exceptional performance in the year 2015. When devastating floods hit Chennai in December 2015, the Management of SN came forward to help the employees by rendering monetary assistance. Employee Satisfaction Surveys were conducted to understand employee morale and job satisfaction levels across all departments of SN.

Academically brilliant children of our employees were given merit awards on Republic Day occasion to further motivate them.

To engage employees, Sankara Nethralaya organized the 20th In-House Cricket match for Dipankar Chatterjee cup which saw huge participation from the employees' side. The SN family celebrated the Foundation Day, Republic Day, Sports Day & the International Women's Day with all joy and enthusiasm. Doctor's Day was also celebrated with great fervour and to mark their special day, gifts were distributed to all the doctors at SN.

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Awards and Recognition to our President & Chairman Emeritus Dr. S. S. Badrinath

Dr. S. S. Badrinath was honored with an Award for completing Platinum Anniversary -75 years of his glorious life, “Celebration Retina - Celebration Life 2015" at a Conference held at the Sahara Star Mumbai and Aditya Jyot Eye Hospital in Mumbai between from 15th to 17th of May 2015 Dr. S. S. Badrinath received IIRSI Gold Medal at ITC Grand Chola, Chennai on 4th July 2015

Dr. S. S. Badrinath received Ambassador Goodwill Award by Lions International held in Chennai on 8th November 2015

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Sankara Nethralaya's service at Tirupati through Sri Srinivasa Sankara Nethralaya The Sri Srinivasa Sankara Nethralaya (SSSN) which was established in the year 2009 by Sri Srinivasa Sankara Nethralaya Trust by Tirumala Tirupati Devastanam (TTD). This centre has screened more than 11124 new patients and has performed 1659 cataract surgeries during the financial year 2015 - 16. (FY 2014 -15: 10941 new patients and 2210 surgeries). The Tulsi Trust is also playing a major role in mobilizing patients for free cataract surgeries at SSSN. Sankara Nethralaya is also exploring the possibilities of expanding the services offered at SSSN in the near future, with support from TTD.

ABOUT OTHER CENTRES OF SANKARA NETHRALAYA 1. Project at Rajarhat, Kolkata: Construction work at our Rajarhat project is at closing stages and we expect the building to be complete in all aspects and expected to be fully operational from December 2016. We hope with this additional facility in place, we would be able to meet the ever growing demand for our services in the eastern region.

2. Aditya Birla Sankara Nethralaya, Kolkata: Aditya Birla Sankara Nethralaya has more strides in reaching out the remotest corners of West Bengal through its community outreach programmes and the team at ABSN is putting their best to meet the ever growing demand for our services. This centre has screened more than 77309 new patients and has performed 10170 surgeries during the financial year 2015 -16. (FY 2014 - 15: 76842 new patients and 9678 surgeries). With regard to community surgeries, the center has performed 3300 free surgeries for FY 2015-16 against 3285 surgeries during FY 2014-15.

3. Sankara Nethralaya, Rameshwaram: The services offered by Sankara Nethralaya's center Rameshwaram has been discontinued since 31.01.2016 due to poor patronage and other reasons.

4. Sankara Nethralaya, Sricity: Sri City has come forward to lease 10 acres of land at a nominal rate of lease rent each year, to Sankara Nethralaya, to set up an eye hospital and research centre. The first tranche of 5 acres was registered on 19th February 2016

Sankara Nethralaya has reached its milestone when it opened its branch at Sricity, and integrated business township situated 65 KM North of Chennai on the Kolkata National Highway. This center was formally inaugurated on 14th April 2013. This center has provided services to more than 5368 patients and has performed more than 180 cataract surgeries during the financial year 2015-16.

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CSR supporters in FY 2015-16 The funding support received towards education, during previous year, from Glaxo Smith Kline Pharmaceuticals Ltd., Mumbai, will be used for the same set of students in this year also. Besides, we also received CSR funding support to our community services from the following Corporates: 1. Sancotrans Pvt Ltd, Chennai 2. Kuehne+Nagel Pvt Ltd, Chennai 3. BHEL, Chennai 4. HPCL LPG bottling plant, Gummudipoondi, Chennai 5. Zrii trust, Chennai 6. TVS Sundaram Industries Ltd., Maraimalainagar, Chennai 7. Nadi Airtech, Madhavaram, Chennai 8. FDC (Pixel) India, Mumbai 9. Amec foster wheeler India Pvt Ltd., Tharamani, Chennai 10. TVS Upasana Ltd. (subsidiary of TVS Sundram fasteners), Chennai 11. Kishinchand Chellaram Foundation, Mumbai 12. MRF Tyres, Chennai 13. Technova Imaging Systems Pvt Ltd., Mumbai 14. Computer Age Management Service Private Limited, Chennai 15. The Peerless General Finance & Investment Company Limited, Kolkata 16. Voltas Limited, Mumbai 17. Clearcorp Dealing Systems ( India) Ltd, Mumbai 18. Housing Development Finance Corporation Ltd, Mumbai 19. Universal Comfort Products Limited, Mumbai

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CONCLUSION The Foundation has recorded one of its peak performances with the net surplus increasing by 2 ½ times and the total income by 20%. The year also saw completion of the Sri. A. Sivasailam block in Chennai and commencing regular operation. The hospital at Rajarhat is almost ready and likely to come into operation soon. Another large project at Thane has also been conceived and Government of Maharashtra/Thane Municipal Corporation has allotted the land on a token lease rent for establishment of a State of Art Eye Care / Academic Centre. Preparations are underway to prepare the blueprint for the hospital and get the approval of the Thane Municipal Corporation. The building of the buses and other vehicles for the Mobile Eye Surgery Unit Project at Jharkhand, supported by the Navajbai Ratan Tata Trust, is progressing as per schedule. The launch of this project is scheduled for July 2016.

Sankara Nethralaya is continuously reinforcing its position as a premier institution in quality eye care. As emphasized by the Founder Visionary, Dr. S. S. Badrinath, Nethralaya is growing on all the 4 focus areas of Ophthalmic Care, Free Treatment to poor patients and Teaching, Training and Fundamental Research. VRF also has performed creditably during the year with more publications to their credit in premier journals and getting into lot of collaborative joint research programmes with premier organizations in India and abroad.

The SN Academy will play a significant role in the coming years and will turn out significant number of qualified personnel in the cause of Eye Care Delivery System in addition to being a revenue earner for Sankara Nethralaya.

NABH final audit of CU Shah Sankara Nethralaya, Chennai took place in March 2016. The auditors found no major non-conformities and have recommended for NABH Accreditation. The certificate is expected to be received in July 2016. Both the Main Campus and JKCN campus in Chennai are already NABH Accredited. Threats & Concerns Over the last few years, the Institution faced continuous threats of competition in the anterior segment and due to consistent efforts now the situation is slowly improving and the capacity utilization of our State of Art facilities are also improving. The compensation package of employees and consultants were also revised to encourage them to continue the good work and to be on par with the opportunities available elsewhere. Sankara Nethralaya's standards of eye care delivery have been accredited with a NABH certification and international recognition. Under the above scenario of severe competition, we have managed to update with newer equipments& techniques and increased the expend for research & training.

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New Projects On invitation from the Municipal Commission, Thane, Maharashtra, Dr. S. S. Badrinath visited Thane. The Municipal Commission has come forward to lease 2 acres of land in Thane for building Sankara Nethralaya Eye Hospital including a teaching and training centre. During his visit, the Memorandum of Understanding for leasing of the land has been signed. Our team headed by our Advisor Projects, Lt. Col. Raghavan and working on the building plan and will be sending the plan for approval to the Thane Municipal Commission

The buses and vehicles for the Mobile Eye Surgery Project, Jharkhand, is under construction. This project is being supported by the Navajbai Ratan Tata Trust. Doctors and paramedical staff have been recruited for the project and are currently undergoing training at Chennai. Tata Steel, Jamshedpur is helping Sankara Nethralaya will setting up a base hospital / office in Jamshedpur and will also be supporting in identifying the camp locations. The project is expected to be inaugurated in July 2016. Human Relations The Founder, Dr. S. S. Badrinath and Dr. Vasanthi Badrinath are the real force behind this great Institution, continuously guiding and monitoring the progress of the Institution in every sphere. Their concerted actions in the continuous development of Consultants and their professional management style with succession plans have started yielding results. The Vice Chairman, Dr. T. S. Surendran, Medical Directors/Senior Consultants Dr. Prema Padmanabhan, Dr. Tarun Sharma, Dr. Pramod Bhende and Dr. L. Vijaya, Dr. J. Biswas all share a common vision as that of the Founder, Dr. S. S. Badrinath, which helps to continue the successful functioning of the Organization. Quality administrative support is provided by Dr. K. S. Vasan, ably assisted by Ms. Akila Ganesan, Senior General Manager and Ms. Susila Girisan, DGM – Finance. Mr. V. Vaidyanathan, Board Member continues to render his expert guidance to ensure the smooth functioning of the organization. Our entire para medical and administrative staffs are an important link between the patients and the institution. They ensure the smooth functioning of the Organization. Regular training classes are being held to some of these groups. I record with gratitude the support of the dedicated Board of Management who despite their other priorities have always come forward to advise the Institution whenever needed even at very short notices. Our auditors, since the beginning of this institution, M/s S. Viswanathan, LLP are carrying out their assignment as a service to a non-for-profit organization for a token compensation. I record with appreciation the personal involvement of the partners Mr. C. N. Ramachandran and Mr. Chella Srinivasan. The internal auditors Mr. S. A. Bhatt are also very dedicated in their service to us. I thank them for their personal involvement in our case.

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SWAN, the women auxiliary wing of our organization is continuing their good service to Sankara Nethralaya. Their contributions to the welfare of indigent patients treated at Nethralaya are praiseworthy. I salute these dedicated ladies guided by Ms. Surekha Ben, Mrs. Appukutty, Mrs. Haridas and many more.

Our bankers, HDFC and SBI, are very considerate in taking up our requests and delivering their service very promptly to us. I thank them for their support.

Lions club collaborate with us in a continuous manner on various sight-related projects. Lions International recognizes our dedicated service to the poor in a very satisfactory manner. Lion M. V. Raghunathan himself a very great donor , Lion G. V. Raman a great motivator, the ever present Lion S. N. Hari Narayanan are all part of us.

I thank them on behalf of our entire organization for their help in taking care of our indigent patients. Mission for Vision Trust, Tulsi Trust, Shridi Sai Trust, Singhvi Trust are all committing funds continuously, supporting the free services rendered by us.

I wish the foundation the very best with the everlasting blessings of His Holiness the Paramacharya of Kanchi Kamakoti Peetam, who with his divine prophecy found a unique human being in Dr. S. S. Badrinath to establish and successfully run this unique organization known world-over.

G.RAMACHANDRAN Honorary Secretary

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ACADEMICS Number of people trained by Sankara Nethralaya in Ophthalmology so far are: A total of 1823 Ophthalmologists trained in vision subspecialties after completion of their Post Graduation DO : 95

DNB : 169

B.S. Optometry : 581

M Phil Optometry : 106

MSMLT : 96

Ph. D (Ophthalmology)*

Microbiology, Biochemistry : 45

Genetics, Pathology and Optometry) :

FRCS Edinburgh : 47

* Ph.D from BITS University – 34, The Tamilnadu Dr.M.G.R. Medical University –5, Ph.D. Sastra University- 4 & Deakin University, Australia - 2 Other Programs in Academics Total No of Students completed their Program

Ophthalmology Fellowship Programme 36

Cataract Fellowship 31

DO 4

DNB 8

B.S Optometry 29

M.Phil Optometry 11

Ph D 8

FRCS 1

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THE SANKARA NETHRALAYA ACADEMY (Performance Highlights of 2015-16)

In Pursuit of Enlightening As visualized by our beloved founder Dr. S. S. Badrinath, TSNA endeavours to offer thriving and wholesome education, in the domain of Allied Health Sciences for the average students. Courses with good career scope alone are identified and offered at affordable cost. Having students from all walks of the society, we reach out to all over India. Comprehensive Education Apart from academic curriculum, TSNA also organizes job oriented skill training programs. Enabling the students trained in soft skills and communication skills, TSNA boast to have near 100% placement record for all courses. After all, as Greek Philosopher Socrates said, education is the kindling of a flame and not just filling of a vessel. Courses Offered in 2015-16 Under Graduate Courses Post Graduate Courses

BSc (Medical Lab Technology) MSc (Medical Lab Technology) BSc (Ophthalmic Dispensing) Masters in Optometry BSc (OD) with FBDO MBA (Hospital & Healthcare Management) BBA (Hospital & Healthcare Management) Master of Hospital Administration Diploma Courses

Diploma in Ophthalmic Nursing Assistant Diploma in Operation Theatre & Anaesthesia Technician Diploma in Refraction & Dispensing

Other Programs Continuing Optometry Education Fellowships in Optometry Clinical Optometry Contact Lens Binocular Vision /Vision Therapy Low Vision Essilor Retail Sales Training Flexible Learning Programs Certificate Course in Hospital Management Certificate Course in Healthcare Quality Management Certificate Course in Hospital Infection Control Certificate in Optical Retail Management PG Program in Optical Retail Management

24 MEDICAL RESEARCH FOUNDATION

University Affiliations & Collaborations Tamil Nadu Dr.MGR Medical University, Chennai Periyar University, Salem Hindustan University, Chennai Industry Collaborations Association of British Dispensing Opticians, UK Titan Eye Plus, Hosur Essilor, Chennai ACME Consulting, Chennai Association of Healthcare Providers (India), New Delhi Healthcare Sector Skill Council, New Delhi International Federation of Infection Control, UK Education with Compassion Pursuing passion for compassion, fee waivers and scholarships are offered on merit cum need basis. Around 40 students were given scholarships worth around rupees Ten lakhs, with the support of donors like GlaxoSmithKline, Sathya Sai Trust, Tulsi Trust etc.

Titan Optical Sales Skill Training With a budget of Rs. 25 lakhs funded by Titan Eye Plus, TSNA organized four batches of Skill Development programs in Optical Retail Sales, covering around 250 students, most of whom were placed.

25 MEDICAL RESEARCH FOUNDATION

Academic Excellence 100% pass and placement in BSc (MLT) and MBA Campus interview conducted by Tattva Home Healthcare Ltd. for MBA students MBA students won university ranks & medals BSc (OD) students won first & second places in inter collegiate competition held by Science City, Chennai (Govt. Of Tamil Nadu) Hindustan University declared three projects of final year MBA students were outstanding and recommended to publish in Healthcare Executive Journal

The Sankara Nethralaya Academy Campus Programs Highlights 49 students enrolled in FBDO and 9 students successfully completed the PQE exams in their first attempt for which they were given ABDO gold badges in appreciation of the same. 7 students successfully completed their Grand FQE exams in the academic year 2015-16 32 students enrolled in Fellowship programs and 12 in Certificate programs in Clinical Optometry, Contact Lens, Binocular Vision / Vision Therapy and Low Vision Two batches of Continuing Optometry Education were conducted on Basic Binocular Vision and Basics of Low Vision Care, with around 105 participants

26 MEDICAL RESEARCH FOUNDATION

Extra-curricular Activities BSc (MLT) and MSc (MLT) students volunteered during Blood Donation camps organized by Voluntary Health Services, Chennai. Students & staff organized distribution of free food packets around the college premises during floods in December 2015. Students and staff organized free eye screening camps in college premises monthly once on Sundays for general public.

Miscellaneous TSNA Organized career counselling for UG & PG courses at various locations in Tamil Nadu (Salem, Pondicherry, Arakkonam and Chennai) and Kerala (Kottayam, Allepey, Palakkad and Kozhikode) Optometry faculty Mr Sathish Kumar was a guest faculty in the Continuing Medical Education program conducted by Regional Institute of Ophthalmology in Trivandrum & Chennai. Head of Department of Optometry Dr. Anuja R Singh was the Chief guest at T. S. Narayansami College Sports day function in March 2016. Head of Department of Optometry Dr. Anuja R Singh was the Chief guest at T. S. Narayansami College Sports day function in March 2016.

27 MEDICAL RESEARCH FOUNDATION

VIDYASAGAR INSTITUTE OF BIOMEDICAL TECHNOLOGY & SCIENCE (VIBS) VIBS was established on 25th October 2006 to promote research including fundamental research and foster biomedical technology and science in Basic Medical Sciences. EDUCATIONAL ACTIVITY OF VIBS I Ph.D PROGRAM: NUMBER OF Ph.D AWARDEES: - (July 2015 – June 2016) = 9 (BITS PILANI- 6, SASTRA University, Thanjavur- 2, Deakin University - 1) Number of candidates obtained Ph.D from BITS, PILANI = 6 S.No. Candidates Name Title Supervisor External Date of Examiner Viva-Voce Examination

1. Dr. Vinita kumari “Association Study , Dr. S. Sripriya, Prof. Dwaipayan 8th (ID No: 2007PHXF427) Analysis for Genetic Associate Professor Bharadwaj, January (SN ONGC Department and Environmental (SN ONGC Dept of from Jawaharlal 2016 of Genetics & Interaction of Genetics & Nehru University, Molecular Variants in Molecular New Delhi Candidate Genes biology) biology) for Inflammation (ICAM-1, CFH) and Neuroprotection (PEDF, EPO) in Type 2 Diabetic Retinopathy Patients from South India”

2. Dr.M.K. Janani ''A Clinico - Dr.J.Malathi BITS Pilani. 11th (ID No: 2010PHXF041P) Molecular Associate Professor Prof. Rajesh January (L & T Microbiology Biological and of L & T Microbiology Kannangai from 2016 Research Centre) Genotypic Study Research Centre Department of on Epstein - & Professor Sanjeev Clinical Virology, Barr virus in Kumar from Biological Microbiology, Chennai Population” Sciences department, Christian Medical BITS Pilani. College (CMC),

3. Dr. M. Bharath Selvi “Biochemical Dr.K.N.Sulochana Prof.Rajaguru, 24th May (ID No: 2009PHXF020P) mechanisms of (Supervisor, Anna University, 2016 (R.S.Mehta Jain Homocysteine R.S.Mehta Jain Trichy Department of and its role in Department of Biochemistry & Retinal Vascular Biochemistry & Diseases” Cell Biology) Cell Biology)

4. Dr.Vimalin Jeyalatha “Prevention of Dr.J.Malathi Dr.Debashish Das, 30th May (ID No: 2010PHXF444P) Corneal Limbal Associate Professor Chief Scientist 2016 (L & T Microbiology Epithelial Cell Death of L & T Microbiology from Narayana Research Centre) during Collagen Cross Research Centre & Nethralaya, Stem linking and the Co-supervisor Cell Research Pathogenic Prof. Suman kapur, Laboratory, Bangalore Mechanisms Involved Dean, Research and in Progression of Consultancy Division, Keratoconus” Professor, Biological Sciences Department.

28 MEDICAL RESEARCH FOUNDATION

S.No. Candidates Name Title Supervisor External Date of Examiner Viva-Voce Examination

5. Dr. Srilatha Jasty “To identify and Dr. S. Krishnakumar Prof Rama 30th (ID No: 2008PHXF019P) characterize the Professor & HOD of S. Verma May 2016 (L & T Ocular retinal stem/progenitor L & T Ocular from IIT Pathology properties of human pathology, Nano Madras. Department) iris pigment epithelial Biotechnology & cells (IE) and ciliary Stem Cell epithelial cells Departments (CE) in-vitro."

6. Mr. Bhuvanasundar “Structure - Functional Dr. K. N. Sulochana Prof Survo 30th (ID No: 2010PHXF445P) Characterization of (Supervisor, Chatterjee, June 2016 (R.S.Mehta Jain Human Lysyl Oxidase R.S. Mehta Jain Research Department of through Molecular Department of Scientist, Biochemistry & Cloning, Expression Biochemistry & AU-KBC and In Silico Studies” Cell Biology) Cell Biology) Research Centre, Chennai.

No. of Candidates obtained Ph.D from SASTRA University , Thanjavur =2 S.No. Candidates Name Title Supervisor Date of 23 Viva-Voce Examination

7. Dr.C.Sathya priya, "Homozygosity mapping Dr. S. Sripriya, 22nd (ID No: PH 257) based genetic analysis Associate Professor January 2016 (SN ONGC Department of autosomal recessive (SN ONGC Department of Genetics & families affected by of Genetics & Molecular biology) Bardet-Biedl syndrome Molecular biology) in Indian population”

8. Dr. A.R. Rajalakshmy, “Molecular Immunology Dr. H. N. Madhavan, 15th (ID No: PH 533) of Ocular Manifestations (Senior Professor & February 2016 (L & T Microbiology and Neuroinvasion of Director of Research Centre) Hepatitis C Virus: L & T Microbiology Immune Response Research Centre) Against Virus and Viral Antigens” No. of Candidates obtained Ph.D from DEAKIN University , Australia = 1 Date of S.No. Candidates Name Title Supervisor Viva-Voce Examination

6. Dr. Sushma Kalmodia “Peptide conjugated Dr. Wenrong Yang, 10th (Department of nano-particles Head, Deakin University, September Nano Biotechnology) mediated therapy Australia & 2015 for eye diseases” Co-Supervisor : Dr. S. Krishna Kumar, Professor & HOD of L & T Ocular Pathology

29 MEDICAL RESEARCH FOUNDATION

NO. OF CANDIDATES SUBMITTED Ph.D FINAL THESIS & AWAITING FINAL VIVA VOCE -3 (BITS, PILANI -2 & TN Dr.MGR Medical University-1) (I) BITS, PILANI: (N = 2) S.No Candidate Name Title Supervisor Date of submission

1. Ms. Shabna A. “In vitro evaluation of the Dr. H. N. Madhavan 18th July (ID No:2010PHXF443P) scope of an indigenously (Senior Professor & 2016 (L & T Microbiology produced Poly hydroxy alkanoate Director of L & T Research Centre) based co-polymer developed Microbiology Research from Pseudomonas MNNG-S in Centre) cell culture and virology"

2. Ms. S. Vidhya “Understanding the role of Dr. K. N. Sulochana 25th adiponectin in pdr; design (ID No: 2010PHXF039P) and development of (Supervisor, R.S.Mehta July 2016 (R.S.Mehta Jain therapeutic molecules” Jain Department of Department of Biochemistry & Biochemistry & Cell Biology) Cell Biology)

(ii) The TN Dr.MGR Medical University: ( N=1)

3. Mr. M. Arun “Design and development of Dr. K. N. Sulochana 21st modulators for Lysyl (ID No: EXII (1) 28210/2011) oxidaser to regulate (Supervisor, R.S.Mehta July 2016 (R.S.Mehta Jain Ocular Angiogenesis” Jain Department of Department of Biochemistry & Biochemistry & Cell Biology) Cell Biology)

NO. OF CANDIDATES SUBMITTED Ph.D FINAL THESIS & AWAITING FINAL VIVA ( N=1) Date of Final submission S.No Candidate Name Title Supervisor of Ph.D. Final thesis SASTRA UNIVERSITY, THANJAVUR : (N =1) 1. Ms. Sasirekha Krishnan An approach to the current Dr. S. Krishna Kumar, 26th (ID No: 09-371/2009) challenges and concepts (Professor & HOD March 2014 (Stem Cell Laboratory) in corneal / limbal of Stem cell biology) Stemcell transplantation (LSCT) procedure for ocular surface reconstruction

2) DRAFT THESIS SUBMISSION : 1 (I) BITS, PILANI: 1 1. Ms. S. Srilekha Genetic Analysis of Dr. N. Soumittra 6th June 2016 (ID No: 2011PHXF427P) Consanguineous with South Associate Professor, (SN ONGC Department Indian families with Leber (SN ONGC Department of Genetics & Congenital Amaurosis and of Genetics & Molecular Biology Retinitis Pigmentosa using Molecular biology) Homozygosity Mapping

30 MEDICAL RESEARCH FOUNDATION

SYNOPSIS SUBMITTED : 1 (ii) THE TAMILNADU Dr. M.G.R. MEDICAL UNIVERSITY, CHENNAI: = 1 S.No Candidate Name Title Supervisor Date of submission

1. Mr. R. Saravanan Identification, molecular Dr.K.N.Sulochana, Submitted Ph.D. (ID No: EXII (1) 28209/2011) cloning and characterization Professor, (R.S.Mehta Synopsis on (R.S.Mehta Jain of differentially expressed Jain Department of 30th March 2015 Department of proteins in the serum of Biochemistry & (Final thesis to be Biochemistry & patients with Eales' disease. Cell Biology) submitted by Cell Biology) January 2017)

III.Total No. of Candidates undergoing Ph.D programme under 5 different Universities (4 Indian + 1 International (Deakin University, Australia): 28

S.No BASIC MEDICAL BITS, SASTRA The Tamilnadu ANNA DEAKIN SCIENCES Pilani University, Dr.M.G.R.Medical University University, DEPARTMENTS,VRF (3) Thanjavur University, Chennai, Australia KNBIRVO BLOCK (N = 28 ) (19) Chennai ( 2 ) ( 2 ) ( 2 ) 1. L & T. Ocular 1 3 - - - Pathology Dept (N=4) 2. Nano Biotechnology - - - 1 2 Department (N=3) 3. SN ONGC Department 2 2 - - - of Genetics & Molecular Biology (N=4) 4. Core Laboratory (N=1) - - - 1 - 5. R.S. Mehta Jain - 10 2 - - Department of Biochemistry and Cell Biology (N=12) 6. Centre for - 3 - - - Bioinformatics (N=3) 7. L & T. Microbiology - 1 - - - Research Centre (N=1) IV. MASTER OF SCIENCE (MS BY RESEARCH) PROGRAMME: NO. OF CANDIDATES SUBMITTED MS FINAL THESIS & AWAITING FINAL VIVA (N=1)

S.No Candidate Name Title Supervisor Date of submission

6. Ms. Sivapriya S Study of identification Dr.S.Ashok kumar 24th (ID No: 1323528702 of biomarkers for (Supervisor), June 2016 (L & T Ocular Age related Anna University, Chennai Pathology macular Dr. J.Narayanan Department) degeneration. (Co-Supervisor) Senior Scientist, Nano Biotechnology Department

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V. OTHER EDUCATIONAL ACTIVITIES CONDUCTED AT VIBS Short term Research Projects for PG students in Biological sciences : 21 students underwent VIBS – Short term projects from “December 2015- April 2016” in the 5 Basic Medical Sciences departments, as part of their academic programme from 5 Engineering Colleges & 2 Arts &Science Colleges.

S.No. Basic Medical Sciences Department No. of students (21) 1. L & T Microbiology Research Centre 3 2. R.S. Mehta Jain Department of Biochemistry & Cell Biology 4 3. Centre for Bioinformatics 3 4. SN ONGC Department of Genetics & Molecular biology 3 5. Department of L & T Ocular Pathology 2 6. Department of Nano Biotechnology 4 7. Department of Core Laboratory 2

VI. One month Hands-on Summer Training Programme in Biomedical laboratory sciences for Postgraduate Science students of Arts & Science Colleges: 9 Post graduate students from 6 Arts and Engineering Colleges & 1 Research Institution underwent Hands on Summer Training programme from “11th May to 31st May 2016” in the following 3 Basic Medical Sciences departments. S.No. Basic Medical Sciences Department No. of students (13) 1. L & T Microbiology Research Centre 4 2. R.S.Mehta Jain Department of Biochemistry & Cell Biology 3 3. SN ONGC Department of Genetics & Molecular biology 2 VII. BITS Practice School I (PS - I) programme for II Year Engineering Graduate students for 7 Weeks (23rd May 2016 – 16th July 2016): PS – I training is provided every year during summer holidays from May to July in the Basic Medical sciences departments. During (23rd MAY-2016 – 16th JULY-2016), 10 BITS students have undergone this training programme. S.No. Basic Medical Sciences Department No. of students (10) 1. L & T Microbiology Research Centre 2 2. R.S. Mehta Department of Biochemistry & Cell Biology 3 3. SN ONGC Department of Genetics & Molecular biology 2 4. L & T Ocular Pathology Department 1 5. Hospital Infection Control16.Vitreo-Retinal Department 1 6. Vitreo-Retinal Department 1

32 MEDICAL RESEARCH FOUNDATION

VIII. Specific Training programs on specialized/advanced Techniques such as PCR/PCR RFLP, RT- PCR, ELISA, HPLC etc. In the year 2015 – 2016, 25 students underwent Special Training programme in the Basic Medical Sciences departments from 12 Arts & Sciences & Engineering Colleges.

S.No. Basic Medical Sciences Department No. of students (26)

1. Stem cell (3), Nano Biotechnology(5), L &T Ocular Pathology Department (7) 15 2. SN ONGC Department of Genetics & Molecular biology 4 3. R.S.Mehta Jain Department of Biochemistry &Cell Biology 1 4. Centre for Bioinformatics 4 5. L & T Microbiology Research Centre 1

TRAINING & DEVELOPMENT The Training and Development Department provides internal and external training to its employees. Training programs are conducted to To enhance the technical and soft skills of employees To keep the employees updated of the latest developments in their respective field Employee Motivation Training sessions are conducted regularly as part of NABH compliance that include- conducted- SN's Vision, Mission and Philosophy Basic Life Support (BLS) Fire Safety Patient Rights and Responsibility Employee Rights and Responsibility Patient/Employee Rights & Responsibilities Service Standards & Standing Orders Classes on Leadership skills, Body and mind healing techniques and sound therapy, Tax planning, Awareness on Breast Cancer, Yoga & Meditation sessions for our staffs were conducted by insightful trainers across all centers of Sankara Nethralaya. To enhance the computer skills of staff, SN in collaboration with DG Vaishnava College had organized a one year Certificate course on “Diploma in Computer Application”. Total number of training programs conducted from April 2015 to March 2016: Technical program: 290 Soft skills program: 183 Language program: 135 Orientation program: 11

33 MEDICAL RESEARCH FOUNDATION

34 MEDICAL RESEARCH FOUNDATION

Training department conducts a five day orientation program for all new employees which orients them on the following:

Day 1 : Introduction, SN Overview, HR(Welfare Measures and Standing Orders) & Finance Day 2 : NABH Awareness, Fire & Safety, DPS (Patient Rights and Responsibilities) & Eye Bank Day 3 : Overview of the facilities & Anatomy of eye Day 4 : Branch Hospital Visit Day 5 : Individual Analysis session & Self Improvement Sessions

BASIC LIFE SUPPORT (BLS) Session had been organised for-

Nursing & Operation Theatre: 85 Nos,

DPS: 51 Nos,

Eye bank & lab: 6 nos

Mesu staffs: 6

Stores staff: 12

ACLS Course had been organized for 13 CONSULTANTS

BLS & ACLS Course had been organized for 36 POSGRADUATES & FELLOWS.

Apart from these, training department also sends staff for External Training programs to upgrade themselves on the recent advancements.

A new department namely Teaching and Training Department was formed with the primary objective to improve performance levels across the organization by using the metrics of Rubrics.

35 MEDICAL RESEARCH FOUNDATION

Independent Auditor's Report To the Members of MEDICAL RESEARCH FOUNDATION for the year ended 31st March 2016. Medical Research Foundation Report on the Financial Statements We have audited the accompanying financial Statements of MEDICAL RESEARCH FOUNDATION which comprises the Balance Sheet as at 31 March, 2016, and the Income and Expenditure account for the year then ended, and a summary of significant accounting policies and other explanatory information. Management's Responsibility for the Financial Statements Management is responsible for the preparation and presentation of these financial statements that give a true and fair view of the financial position, financial performance of the trust in accordance with the Accounting Standards. This responsibility includes the maintenance of adequate accounting records in accordance with the provisions of the Act for safeguarding the assets of the trust and for preventing and detecting frauds and other irregularities; selection and application of appropriate accounting policies; making judgements and estimates that are reasonable and prudent; and design, implementation and maintenance of adequate internal financial controls, that were operating effectively for ensuring the accuracy and completeness of the accounting records, relevant to the preparation and presentation of the financial statements that give a true and fair view and are free from material misstatement, whether due to fraud or error. Auditor's Responsibility Our responsibility is to express an opinion on these financial statements based on our audit.We conducted our audit in accordance with the Standards on Auditing issued by the Institute of Chartered Accountants of India (ICAI) .Those Standards require that we comply with ethical requirements and plan and perform the audit to obtain reasonable assurance about whether the financial statements are free from material misstatement. An audit involves performing procedures to obtain audit evidence about the amounts and the disclosures in the financial statements. The procedures selected depend on the auditor's judgment, including the assessment of the risks of material misstatement of the financial statements, whether due to fraud or error. In making those risk assessments, the auditor considers internal control relevant to the Trust's preparation and fair presentation of the financial statements in order to design audit procedures that are appropriate in the circumstances but not for the purpose of expressing an opinion on whether the trust has in place an adequate internal controls system over financial reporting and operating effectiveness of such controls.An audit also includes evaluating the appropriateness of the accounting policies used and the reasonableness of the accounting estimates made by the management, as well as evaluating the overall presentation of the financial statements. We believe that the audit evidence we have obtained is sufficient and appropriate to provide a basis for our audit opinion. Opinion In our opinion and to the best of our information and according to the explanations given to us, the financial statements give the information required by the Act in the manner so required and give a true and fair view in conformity with the accounting principles generally accepted in India. a) In the case of the Balance Sheet, of the state of affairs of the Trust as at March 31, 2016 b) In the case of Income and expenditure account , of the Excess of Income over expenditure for the year ended on that date; For M/s. S.VISWANATHAN, LLP Chartered Accountants Regn No: 004770S / S200025 Chella K. Srinivasan Place: Chennai Partner Date : 06.08.2016 Membership No: .023305

36 MEDICAL RESEARCH FOUNDATION BALANCE SHEET AS AT 31st MARCH 2016 AS AT 31.03.16 AS AT 31.03.15

PARTICULARS SCHEDULE Rs. Rs. Rs. Rs.

LIABILITIES CORPUS FUND DONATION u/s 35AC As per Last B/S 249853312 235118311 Add: Donations received during the year- Corpus 13623251 14700001 Add: Donations received during the year: SN Mahema Devadoss Endowment Fund 0 263476563 35000 249853312

SIR RATAN TATA TRUST CORPUS FUND SRTT CORPUS FUND 62765816 62018816 MRF CORPUS FUND 52031507 114797323 51403507 113422323

GENERAL FUND I 1758800653 1412393137 EARMARKED FUNDS II 57698989 62214787 NON CURRENT LIABILITIES ICICI TermLoan (TI-Project) 300000000 350000000 Gratuity Liability 53528359 48258940 Leave Encashment Liability 38926569 392454928 15708843 413967783

Current Liabilities & Provisions III 223191287 201650473

Grant Advance - H T Parekh Foundation 10000000 10000000

Navajbai Ratan Tata Trust 44684261 -

TOTAL LIABILITIES 2865104003 2463501816

ASSETS FIXED ASSETS IV Gross Block As on 31.03.2016 2332671602 2239417934 Depreciation 1335891613 1226226764 Net Block 996779988 1013191170 Fixed Assets not put in use 233165885 151349152 Capital Work in Progress 466935360 215465826 Net Fixed Assets as on 31.03.2016 1696881233 1380006148

Investments V 381419852 373156822

Current Assets VI 786802919 710338846 TOTAL ASSETS 2865104003 2463501816

We declare that the particulars furnished above are true and correct to the best of our knowledge and belief. Examined and found correct as per the books maintained by Medical Research Foundation (Regd.) Chennai.

SUGALCHAND JAIN N. M/S. S. VISWANATHAN, LLP RAMACHANDRAN G Chartered Accountants Hony. Treasurer 17, Bishop Wallers Avenue (west) C I T Colony, Mylapore, Chennai 4 Hony. Secretary DATED : 06.08.2016 CHELLA K. SRINIVASAN Partner Membership No: .023305 37 MEDICAL RESEARCH FOUNDATION

INCOME AND EXPENDITURE ACCOUNT FOR THE YEAR ENDED 31.03.2016 31.03.2016 31.03.2015

PARTICULARS Rs. Rs.

INCOME SCHEDULE

Hospital Collections 1597421575 1445984068 Donations for meeting Running Cost 159007081 76158587 Grants 12001594 9111985 Interest 55679875 47281689 Other Income 98063891 38190752

TOTAL 1922174016 1616727082

EXPENDITURE

Salaries, Wages & Employee Benefits VII 641940168 567328620 Hospital Expenses VIII 753257441 692470377 Administration Expenses IX 166489102 139022070 Interest X 3384247 3500000

TOTAL 1565070958 1402321068

Surplus before Depreciation 357103058 214406014

DEPRECIATION 109664850 111581569

INCOME OVER EXPENDITURE 247438208 102824445

We declare that the particulars furnished above are true and correct to the best of our knowledge and belief.

SUGALCHAND JAIN N. RAMACHANDRAN G Hony. Treasurer Hony. Secretary

Examined and found correct as per the books maintained by Medical Research Foundation (Regd.) Chennai.

M/S. S. VISWANATHAN LLP Chartered Accountants 17, Bishop Wallers Avenue (west) C I T Colony, Mylapore, Chennai 4 Dated: 06.08.2016

38 MEDICAL RESEARCH FOUNDATION

SCHEDULES TO BALANCE SHEET AS AT 31st MARCH 2016 AS AT 31.03.16 AS AT 31.03.15

PARTICULARS Rs. Rs. Rs. Rs.

SCHEDULE 1

GENERAL FUND As per Last B/S 1412393137 1189483964 Add: Donations received during the year 98969307 120084729 Add: Excess of Income Over Expenditure 247438208 102824445 Total General Fund 1758800653 1412393137 SCHEDULE II

EARMARKED FUNDS Sir Ratan Tata - Phase III 30657 29464 SN Mahema Devadoss Endowment Fund 1266373 1285323 Sri Ramdoss Bhavani Nethralaya Endowment 100000 100000 Dhingra Family Trust - Fund 1000000 1000000 Trent Ltd 1500000 1500000 Titan Industries Ltd 1477959 5000000 GlaxoSmithkline Pharmaceuticals Limited 2324000 3300000 Infosys Foundation 50000000 50000000 Total Earmarked Funds 57698989 62214787

SCHEDULE III

CURRENT LIABILITIES & PROVISIONS Sundry Creditors - Suppliers 115886237 91673821 Sundry Creditors - Bills payable 11846878 4007920 Sundry Creditors - (Deferred Payment) 41412935 60272760 Salary Payable 9118399 5728109 Security Deposit - Employees - 72683 Security Deposit - Contractors 9091923 2903407 Security Deposit - Others 20000000 20000000 Contingency Fund 1817165 1552025 Provision for VAT Liability 10540187 10540187 Others 3477563 4899560 Total Current Liabilities & Provisions 223191287 201650473

39 MEDICAL RESEARCH FOUNDATION

SCHEDULES TO BALANCE SHEET AS AT 31st MARCH 2016 AS AT 31.03.16 AS AT 31.03.15

PARTICULARS Rs. Rs. Rs. Rs.

SCHEDULE V

Investments SRTT Corpus 55000000 55000000 SRTT Corpus - Interest 7765816 62765816 7018816 62018816

MRF Corpus 45000000 45000000 MRF Corpus - Interest 7031507 52031507 6403507 51403507

Corpus Fund-PS Foundation 5000000 5000000

SN Mahema Devadoss Endowment Fund 5060000 5060000

Other Corpus Investments 256562529 249674499

Total Investments 381419852 373156822

SCHEDULE VI

CURRENT ASSETS Cash & Bank Balances Cash & Cheques on Hand 3797927 2197276 Bank Balances - in Savings Account 30943372 35799588 - in Fixed Deposits 471104291 505845590 318929989 356926853

Loans & Advances 96118368 209868137 Deposits 12461543 12097865 Inventories 23055604 19562183 Sundry Debtors 52868301 51664304 TDS Receivable 31276651 12490867 Interest Receivable 45322279 32407577 Prepaid Expenses 19854583 15321060 Total Current Assets 786802919 710338846

40 Rs. 98761 53214 342662 4029543 5460425 as at 22492493 29799172 22151495 10733965 260040549 264518930 268000683 109058097 996779988 466935360 233165885 31.03.16 1696881233 Rs. BLOCK Schedule - IV TION 76021 NET 342662 109735 3515339 5215505 as at 26461756 25955733 21336416 11453724 260040549 278440980 276886445 103356304 215465826 151349152 31.03.15 1013191170 1380006148 - - Rs. 342615 237678 as at 1105047 62889681 13785393 51607978 31708331 18993386 31.03.16 224630602 688950314 107094615 134545974 1335891614 0 0 10974 22807 otal 679978 T 3969263 6346334 3619355 3180851 1223725 2015-16 13922049 65352211 11337303 109664850 TION THE Deletion FOR YEAR 2015-16 584906 584906 Rs. DEPRECIA THE 10974 22806 679978 RESEARCH FOUNDA 3969263 6346334 3619355 2595945 1223725 FOR 13922049 65352211 11337303 Depreciation 109079943 YEAR 2015-16 - - Rs. ill T 342615 226704 1082241 31.03.15 58920418 13105415 47988623 28527480 17769661 210708553 623598103 100748281 123208671 1226226764 Rs. MEDICAL 685277 336439 as at 1158261 85382174 17814936 73759473 42442296 24453810 31.03.16 260040549 489149532 956950997 136893787 243604071 466935360 233165885 2332671602 2239417934 - - Rs. 23166 17880 167009 160518 203888 1002875 6645483 1463203 1732547 1125289 6503636 Deletions 19045494 18454587 ASSETS Rs. Deletions ear 2015-16 During the 590906 590906 148368 Y - - FIXED Rs. ransfer not put in use Rs.4193278/- capitalised during the year 2015-16 T as at 23166 17880 167009 160518 203888 Deletions 1002875 6645483 1463203 1732547 1125289 5912730 31.03.2015 18454587 18306219 0 0 0 0 0 - Asset Rs. 2015-16 1194182 4434434 3052000 1468640 Additions 56466449 10189773 17039096 93844574 81816733 170668796 251469534 GROSS BLOCK Rs. 352668 8827675 3283634 3052000 1131040 2nd Half 13183679 14044750 43875446 92176155 14171462 ADDITIONS 161184465 Rs. 841514 337600 1362098 1150800 2994346 1st Half 43282770 49969128 78492641 90285069 67645271 ADDITIONS Rs. aluation 685277 359605 as at 1176141 87114721 16781272 69528927 45893932 22985170 01.04.15 261043424 495795015 901947751 126871023 227690264 215465826 151349152 2257872521 2087203725 Cost V rogress" % 5% 20% 15% 20% 15% 15% 10% 10% 20% 30% 20% ork in P IN USE TIONS TY Y PUT ALLA Assets not put in use Rs.14044373/- capitalised & MARCH, 2016 INST ear Y BOOKS WORK-IN-PROGRESS including Capital W Y ARE & MACHINER ASSETS NOT - 31ST AL AL EQUIPMENTS AL OT OT revious DESCRIPTION LAND LEASEHOLD PROPER BUILDING EQUIPMENTS & INSTRUMENTS PLANT EDP OFFICE EQUIPMENTS FURNITURE & FIXTURES ELECTRICAL LIBRAR VEHICLE MESS / CANTEEN EQUIPMENTS SOFTW T P CAPIT FIXED "T Note: Fixed

41 MEDICAL RESEARCH FOUNDATION

SCHEDULES TO INCOME AND EXPENDITURE ACCOUNT

PARTICULARS 31.03.2016 31.03.2015

Rs. Rs. SCHEDULE - VII

SALARIES, WAGES & EMPLOYEE BENEFITS Salaries & Wages 447527467 395205292 Contribution to Provident Fund 18395252 17610065 Staff Welfare Expenses 77515408 70573659 Contribution to Superannuation Fund 8208457 7933234 Professional Fees 90293584 76006370 641940168 567328620

SCHEDULE - VIII

HOSPITAL EXPENSES Drugs & Consumables 472501207 429326984 Power, Fuel & Water 74154884 67061665 Repairs & Maintenance 118214859 99574973 Insurance 2820991 2310532 Lab Expenses 24240359 21574496 Rent, Rates & Taxes 61325141 72621727 753257441 692470377

SCHEDULE - IX

ADMINISTRATION EXPENSES Information Techonology Expenses 18057369 18344521 Academic Expenses 38760864 31896455 Communication Expenses 5785213 6017918 Printing & Stationery 10077322 11037085 Vehicle Expenses 8546206 9026743 Security Services 18709762 16030169 Camp Expenses 5818523 5179105 Travelling and Conveyance 4414480 4325951 Books & Perodicals 2836107 2517555 Publicity Expenses 3059481 5601434 Conference 33178477 12042695 Loss On Sale Of Assets 32399 10121 Subscription/Membership 619286 752254 Function Expenses 5455624 5459255 Legal & Audit Fees 789592 1073919 Bank Charges 5548194 4576271 Management Consultancy Expenses 1868585 2948691 Miscellaneous Expenses 2931618 2181928 166489102 139022070

SCHEDULE - X INTEREST Interest on ICICI Term Loan 3384247 3500000 3384247 3500000

42 MEDICAL RESEARCH FOUNDATION

SUB SCHEDULES TO BALANCE SHEET AS AT 31st MARCH 2016 AS AT 31.03.2016 AS AT 31.03.15

PARTICULARS Rs. Rs. Rs. Rs.

1. CASH AND BANK BALANCES

Cash and Cheques on hand 3797927 2197276 Bank Balances (i) Savings Bank Account Andhra Bank 570865 544976 Indian Overseas Bank - College Road 3757776 3761005 State Bank of India - Guindy 4871291 101648 State Bank Of India - Nungambakkam 1617801 2323552 State Bank Of Mauritius -Cathedral Road 85045 145362 HDFC Bank - Mount Road 114136 109695 HDFC Bank - Nungambakkam 3295495 14539152 HDFC Bank - Corpus-Nungambakkam 1001624 2285482 HDFC Bank - Malleshwaram - 343 HDFC Bank - Kolkata 2189190 4185822 HDFC Bank - CA-Nungambakkam 1934594 375066 ICICI Bank - Nungambakkam 483116 568939 Development Credit Bank Ltd - Nungambakkam 507004 1686181 HDFC Bank - SRTT MRF-Nungambakkam 30657 29464 State Bank Of India - Tada 1248245 307320 IOB-Mahema Devadoss Endowment Fund-SN-College Road 2454433 2316988 Citi Bank - Alwarpet 105254 90254 City Union Bank - Purasawalkam 298496 870073 IDBI Bank Ltd - Greams Raod 1320412 959323 State Bank of India - Mukundapur 1068657 598943 HDFC Bank - Nungambakkam - NRTT 3989281 30943372 - 35799588

(ii) Fixed Deposits 376104291 253929989 (iii) Fixed Deposit - HTP Foundation 10000000 10000000 (iv) Fixed Deposit - Infosys Foundation 50000000 50000000 (v) Fixed Deposit - Voltas 5000000 5000000 (vi) Fixed Deposit - NRTT 30000000 471104291 - 318929989

505845590 356926853 2. LOANS & ADVANCES Employees' - Loan 11060872 10615445 Advance for Purchases/Contracts 49615933 167133216 Rent Advance 27545517 24611773 Others 7896047 96118368 7507703 209868137

3. DEPOSITS T.N.E.B 10895997 10660987 Telephone 272270 274552 Others 1293276 12461543 1162326 12097865

43 MEDICAL RESEARCH FOUNDATION

NOTES FORMING PART OF ACCOUNTS FOR THE FINANCIAL YEAR ENDED 31.03.2016

I. ACCOUNTING POLICIES

1. The Foundation follows mercantile system of accounting and recognizes Income and Expenditure on accrual basis. 2. Financial Statements are prepared under historical cost convention. 3. The Fixed Assets of the Foundation are valued at cost less depreciation. 4. Inventories have been valued at Cost. 5. The Foundation's contribution to various schemes of retirement benefits such as Provident Fund and Superannuation Fund are charged to the Income and Expenditure Account every year. 6. The expenditure on unavailed leave of employees allowed to be encashed by them as per rules of the foundation. 7. Gratuity and Leave Encashment provision have been created on the basis of actuarial valuation. 8. Donation and Grants received towards Capital Purchases are accounted under Capital Fund. 9. Donations received for Community Services accounted under Income Statement.

II. Schedules I to VI of the Balance Sheet and Schedules VII to X of the Income and Expenditure Account form an integral part of the Balance Sheet.

III. Previous year figures have been regrouped wherever necessary to conform to current year's classification.

IV. Statutory Audit fees Rs.85875/-

SUGALCHAND JAIN N. RAMACHANDRAN G Hony. Treasurer Hony. Secretary

CHELLA K. SRINIVASAN Partner M/S. S VISWANATHAN LLP Dated : 06.08.2016 Membership No: .023305 Chartered Accountants

44 MEDICAL RESEARCH FOUNDATION

HONOURS & AWARDS Ms. Moutushy Mitra was awarded the Ph.D degree at Sastra University, Thanjavur on 13th April 2015, for her thesis entitled, “To investigate the effect of Tiam (T Lymphoma invasion and metastasis suppressor) siRNA on tumor cell survival proliferation in retinoblastoma” Mr. K. Gopinath was awarded the Ph.D at Sastra University, Thanjavur on 20th March 2015 for the thesis entitled “Role of the endocannabinoid system in retinal Muller glial innate immunity”. Ms. Jaisy Samuel, was awarded the Ph.D at Deakin University , Australia on 9th December 2014 for the thesis entitled “Targeting the sodium iodide symporter (NIS) and apoptotic genes in extrathyroidal tumors“ Ms. Nithya Subramanian was awarded the Ph.D degree at Deakin University, Australia on 21st April 2015 for the thesis entitled, “Molecular Insights and ligonucleotide Based Targeted Gene Therapy against Cancer” Dr. K Padma Lakshmi won the “Divya Chaturvedi Gold Medal award” for her outstanding performance on the paper “Sub-speciality of Uveitis and Inflammatory Diseases”, in the DNB examinations held in April 2015. Dr. L. Dhanurekha was awarded Ph.D degree at BITS Pilani on 16th May 2015 for the thesis entitled, Phenotypic and Genotypic methods for Rapid Detection and Drug (First and Second line) Resistance of Tuberculosis” Dr. Iyer Gomathy Narayanan was awarded the Ph.D degree at BITS Pilani 18th May 2015 for the thesis entitled, “Design & Development of small molecule inhibitors Targeting Copper Transporter1 in Copper Mediated Angiogenesis” Dr S S Badrinath was honored with an Award for completing Platinum Anniversary -75 years of his glorious life, “Celebration Retina - Celebration Life 2015´ at a Conference held at the Sahara Star Mumbai and Aditya Jyot Eye Hospital in Mumbai between from 15th to 17th of May 2015. Dr. T. S. Surendran and Dr. Tarun Sharma gave a speech on blindness at a book release function held at Rashtrapati Bhavan. The President of India, Shri. Pranab Mukherjee released “Yogikasparsh” - a yoga manual in Braille written by Mrs. Nivedita Joshi. Ms. V. Nalini was awarded Ph.D degree at BITS Pilani on 26th June 2015 for the thesis entitled, “Experimental Evaluation of Molecular Targets for the Clinical management of Ocular Cancers (Retinoblastoma and Uveal Melanoma)”. Dr S. S. Badrinath was presented a Gold Medal for his contribution to ophthalmology, by the Minister for Health and Family Welfare, Dr C Vijaya Baskar at the Annual Convention Inaugural Meeting of the Indian Intraocular Implant and Refractive Society, India (IIRSI) at ITC Grand Chola, Chennai on 4th July 2015. Ms S. Srilekha received the Travel Fellowship for attending the 22nd Annual Meeting of Indian Eye Research Group (IERG) ARVO Conference held at L.V.Prasad Eye Institute (LVPEI) Hyderabad from 25th to 26th July 2015. Dr Vathsalya Vijay received the “Best Paper Award” for “Combined Radiological and Surgical Intervention for Peri-orbital AV Malformation” at the Curbside Clinix CME held at Narayana Nethralaya, Bangalore, on 9th August 2015 Dr. J Biswas was elected as the President of the Inflammation Society of India on 22nd August 2015 at the annual meeting held in ChanRe Rheumatology and Immunology Center and Research, Bangalore.

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The Terry Fox Foundation at IIT Madras conducted the “Terry Fox Run – A Marathon of Hope” on 23rd August 2015 to raise funds for cancer research and Vision Research Foundation was chosen as the beneficiary of its assistance for the year 2015. Dr. J. Biswas received Prof. E. T. Selvam Oration Award at Regional Institute of Ophthalmology & Government Ophthalmic Hospital, Chennai on 23rd September 2015. Mr R. N. Naresh Kumar and Ms. Gayathree K attended the 3rd International Conference in Angiogenesis: Techniques and Therapeutics held at Sastra University, Thanjavur on 23rd and 24th September 2015. Ms. Gayathree received the Best Poster Award for “Hyperglycemia induces early growth response-1 (EGR1) in human diabetic retina mediating abnormal vascular changes in diabetic retinopathy” and Mr R. N. Naresh Kumar's paper entitled “Lysyl oxidase propeptide (LOX-PP) inhibits VEGF mediated angiogenesis by down-regulating FAK signalling” was selected for oral presentation under the Young scientist category and he received a shield. Ms. M. K. Janani & Ms. M. Vimalin Jayalatha participated in the IAMM Conference in Clinical Microbiology ARISE – 2015 held at SRM University, Chennai, on the 28th September 2015. Ms. Janani won the First Prize for poster presentation entitled “Novel Immune Regulatory Pathway Associated with Epstein Barr Virus (EBV) and the Recombinant EBV Protein Mediated Inflammation in Retinal Pigment” and Ms. M. Vimalin Jayalatha won the second Prize for poster presentation entitled “Response of Retinal Pigment Epithelial Cells towards Leptospiral recurrent Uveitis Antigens”. Dr. Smitha Praveen received the highly prestigious 'Smt. Pushpa Rani Pattanayek Award' for excellence in community services for the year 2014- 15 at the Annual Conference of the Association of Community Ophthalmologists of India (ACOIN) on 31st October 2015 at Lucknow. Mr. Ravikant Danda received the Travel Fellowship from Department of Biotechnology, Government of India and attended the 14th Human Proteome Organization World Congress HUPO Conference held at Vancouver, Canada from 27th September to 1st October 2015. Dr S S Badrinath was honoured with “Ambassador of Goodwill”, by the International Association of Lions Clubs, for his dedicated service to society on the 8th November 2015 at the Taj Connemara Hotel, Chennai. Dr Lingam Gopal was honored with the Life Time Achievement Award, in Khoo Tek Puat Hospital of Singapore. Dr. Nivedita Chatterjee was awarded the Australia Award Fellowship 2015 by the Department of Foreign Affairs and Trade, Government of Australia. She availed the fellowship at the University of Melbourne, Melbourne, Australia at the Department of Optometry and Vision Sciences from 2nd October to 17th November, 2015. Mr. N. Murugan, received the “Best Poster in Bacteriology” for the poster entitled “Development and Application of Set of Multiplex PCR for rapid diagnosis of drug resistant genes among clinical isolates of Pseudomonas aeruginosa” presented (Oral Presentation) at the 39th National Conference of the IAMM held at JIPMER, Puducherry from 27th to 29th November 2015. Ms. A. R. Rajalakshmy received the Young Woman Scientist Award in memory of Smt. Sreerangamma N. Narayan and Smt. Radhamani N. Anantha for the year 2015 at the 27th Graduation Ceremony of Sankara Nethralaya held at Sri. V.D. Swami Auditorium, on 28th November 2015. Ms. Ferdina Marie Sharmila received the Ph.D degree for her thesis entitled “Gene Mapping of Ocular Quantitative Traits” on 28th November 2015 at BITS, Pilani.

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Ms. N. N. Srikrupa received Swarnalatha Punshi Best Researcher Award in Basic Science for the year 2015 at the 27th Graduation Ceremony of Sankara Nethralaya held at Sri V.D. Swami Auditorium on 28th November 2015. Dr. Rajeswari Mahadevan was honored the “Asia Pacific Regional President” of the International Association of Contact Lens Educators, an educational association dedicated to raising the standard of contact lens education and promoting the safe use of contact lenses worldwide. Ms. Jameel Rizwana H and Ms. Rashima A received the “Endeavour Executive Fellowship Merit Award 2016” from the Department of Education & Training, Australian Government. Dr. Sanjana Suresh Rao, PG Student, won the Dr. S. Kanthimathynathan Endowment Gold Medal Award for Neuro-Ophthalmology. Dr. A V Sai Jyothi received the Prof S Krishnamoorthy Rao Gold Medal for the year 2015, for the Best Outgoing PhD Student at the 27th Graduation ceremony of Sankara Nethralaya on 28th November2015. Dr. V. Umashankar received the Early Career Research Award grant under Young Scientist Scheme – 2015 from Science & Engineering Research Board, Department of Science & Technology, Govt. of India. Dr. V. Umashankar has been selected as Member, Board of Studies for Bioinformatics, University of Madras, for the year 2016. Ms. Vinita kumari was awarded Ph.D degree at BITS Pilani on 8th January 2016 for the thesis entitled, “Association Study, Analysis for Genetic and Environmental Interaction of Variants in Candidate Genes for Inflammation (ICAM-1, CFH) and Neuroprotection (PEDF, EPO) in Type 2 Diabetic Retinopathy Patients from South India” Ms. M.K. Janani was awarded Ph.D degree at BITS, Pilani on 11th January 2016 for the thesis entitled “A Clinico - Molecular Biological and Genotypic Study on Epstein - Barr virus in Chennai Population”. Ms. C. Sathyapriya was awarded Ph.D degree at Sastra University, Thanjavur on 22nd January 2016 for the thesis entitled, “Homozygosity mapping based genetic analysis of autosomal recessive families affected by Bardet-Biedl syndrome in Indian population” Ms. A R Rajalakshmy, was awarded Ph.D degree at Sastra University, Thanjavur on 15th February 2016 for the thesis entitled, “Molecular Immunology of Ocular Manifestations and Neuroinvasion of Hepatitis C Virus: Immune Response Against Virus and Viral Antigens”. Dr Pukraj Rishi received the Best Paper Award for the paper entitled “Intra-arterial chemotherapy in eyes with retinoblastoma” at the AIOS conference held at Kolkata from 24th to 28th February 2016. Dr T. S. Surendran was conferred the highly prestigious 'Fellowship of the Royal college of Surgeons' (FRCS), the world's highest professional qualification for Surgeons, by the Royal College of Surgeons of Edinburgh in March 2016.

47 MEDICAL RESEARCH FOUNDATION

RESEARCH PUBLICATIONS PUBLISHED: R. Roy, D. Das, S. Kumar, and A. Mukherjee, “Postcataract surgery endophthalmitis caused by acinetobacter lwoffii.,” Middle East Afr. J. Ophthalmol., vol. 22, no. 2, pp. 253–4, 2015. Mukherjee, A. Desai, S. Krishnakumar, and J. Biswas, “A Giant Apocrine Hidrocystoma Presenting as Lacrimal Gland Mass.,” Orbit, vol. 34, no. 6, pp. 342–4, 2015. S. Sivasankar, R. Lavanya, P. Brindha, and N. Angayarkanni, “Aqueous and alcoholic extracts of Triphala and their active compounds chebulagic acid and chebulinic acid prevented epithelial to mesenchymal transition in retinal pigment epithelial cells, by inhibiting SMAD-3 phosphorylation.,” PLoS One, vol. 10, no. 3, p. e0120512, 2015. M. Bipasha and P. Devi, “Lipoid proteinosis: A rare entity,” Indian J. Ophthalmol., vol. 63, no. 8, p. 680, 2015. M. Kazi, V. Sharma, S. Kumar, and P. Bhende, “Indications and outcomes of scleral buckle removal in a tertiary eye care center in South India,” Oman J. Ophthalmol., vol. 8, no. 3, p. 171, 2015. S. John, M. Premila, M. Javed, G. Vikas, and A. Wagholikar, “A Pilot Study to Improve Access to Eye Care Services for Patients in Rural India by Implementing Community Ophthalmology through Innovative Telehealth Technology.,” Stud. Health Technol. Inform., vol. 214, pp. 139–45, 2015. John, V. Umashankar, S. Krishnakumar, and P. R. Deepa, “Comparative Modeling and Molecular Dynamics Simulation of Substrate Binding in Human Fatty Acid Synthase: Enoyl Reductase and β-Ketoacyl Reductase Catalytic Domains.,” Genomics Inform., vol. 13, no. 1, pp. 15–24,2015. G. Iyer, B. Srinivasan, E. Rishi, P. Rishi, S. Agarwal, and N. Subramanian, “Large lamellar corneoscleral grafts: tectonic role in initial management of severe ocular chemical injuries.,” Eur. J. Ophthalmol., vol. 26, no. 1, pp. 12–7, 2015. S. I. Shaikh, J. Biswas, and P. Rishi, “Nodular syphilitic scleritis masquerading as an ocular tumor.,” J. Ophthalmic Inflamm. Infect., vol. 5, p. 8, 2015. Archayeeta Rakshit, Kalpa Negiloni, Sumita Agarkar, Jameel Rizwana H. “Improvement and Sustainability of Visual Functions with Action Videogame Play in an Adult with Amblyopia: A Case Report.,” Int. J. Heal. Sci. Res., vol. 5, no. 11, pp. 464–467, 2015. T. Das, R. Raman, K. Ramasamy, and P. K. Rani, “Telemedicine in diabetic retinopathy: current status and future directions.,” Middle East Afr. J. Ophthalmol., vol. 22, no. 2, pp. 174–8, 2015. Gondchawar, J. Biswas, S. Murali, and L. Eawaran, “A case of herpes simplex keratouveitis diagnosed by real time polymerase chain reaction,” Indian J. Ophthalmol., vol. 63, no. 11, p. 854, 2015. Bharathi Devi SR, Coral K, Sulochanan KN, and Angayarkanni N, “Free Amino Acids Glycine and Glutami Acid Inhibit Angiogenesis Induced by AGE in Bovine Retinal Endothelial Cells,” J. Glycomics Lipidomics, vol. 05, no. 02, 2015. S. Ganesh and A. Kaduskar, “Optic nerve head granuloma as a primary manifestation of ocular sarcoidosis - A tertiary uveitis clinic experience,” Oman J. Ophthalmol., vol. 8, no. 3, p. 157, 2015. M. K. Janani, J. Malathi, A. Appaswamy, N. R. Singha, and H. N. Madhavan, “A hospital based pilot study on Epstein-Barr virus in suspected infectious mononucleosis pediatric patients in India,” J. Infect. Dev. Ctries., vol. 9, no. 10, pp. 1133–1138, Oct. 2015.

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S. Kalmodia, S. Vandhana, B. R. Tejaswini Rama, B. Jayashree, T. Sreenivasan Seethalakshmi, V. Umashankar, W. Yang, C. J. Barrow, S. Krishnakumar, and S. V Elchuri, “Bio-conjugation of antioxidant peptide on surface-modified gold nanoparticles: a novel approach to enhance the radical scavenging property in cancer cell.,” Cancer Nanotechnol., vol. 7, p. 1. H. N. Madhavan, R. Bagyalakshmi, P. Aarthi, C. Ashok, A. Prakash, M. Sowmiya, B. Ninan, and M. Revathy, “A Study in Neonatal Sepsis Using Polymerase Chain Reaction-Based DNA Sequencing to Detect the Aetiological Agent in the Peripheral Blood of the Neonates with Sepsis,” Int.J.Curr.Microbiol.App.Sci, vol. 4, no. 9, pp. 415–427, 2015. J. Malathi, M. Janani, N. Murugan, and M. Hn, “Draft Genome Sequence Of Human Herpes Virus-4 Vrf_Ebv_01, An Epstein Barr Virus Obtained From A Pediatric Post Transplant Lymphoproliferative Disorder (Ptld) Patient,” Int. J. Pharm. Pharm. Sci., vol. 7, no. 9, pp. 513–514, 2015. G. Mathur, D. Ratra, S. S. Bhuibhar, and R. Roy, “Clinical Outcomes of Retinal Detachment Surgery following Cytomegalovirus Retinitis in Patients on Highly Active Anti-retroviral Therapy for Acquired Immune Deficiency Syndrome.,” Ocul. Immunol. Inflamm., vol. 23, no. 5, pp. 400–4, 2015. B. Mukherjee, “A Stitch in Time…,” Ophthal. Plast. Reconstr. Surg., vol. 31, no. 6, pp. 492–494, 2015. N. Murugan, J. Malathi, V. Umashankar, and Madhavan HN, “First Complete Genome Sequence Of Ocular Isolate Carrying Blavim-2 Mediated Multi-Drug-Resistant(Mdr) Pseudomonas Aeruginosa Vrfpa04 From India And Two Draft Genome Sequence Of Ocular Isolates Pseudomonas Aeruginosa Vrfpa03 And Vrfpa05 Harboring Novel Bla,” Int. J. Pharm. Pharm. Sci., vol. 7, no. 12, pp. 291–292, 2015. N. Murugan, J. Malathi, K. L. Therese, and H. N. Madhavan, “Antimicrobial Susceptibility And Prevalence Of Extended Spectrum Betalactamase (Esbl) And Metallo Betalactamase (Mbl) And Its Co-Existence Among Pseudomonas Aeruginosa Recovered From Ocular Infections,” Int. J. Pharm. Pharm. Sci., vol. 7, no. 5, pp. 147–151, 2015. N. Murugan, J. Malathi, V. Umashankar, and H. N. Madhavan, “Draft genome sequence of blaVeb-1, blaoxa-10 producing multi-drug resistant (MDR) Pseudomonas aeruginosa strain VRFPA09 recovered from bloodstream infection.,” Braz. J. Microbiol., vol. 46, no. 3, pp. 639–40, 2015. N. Murugan, J. Malathi, K. L. Therese, and H. N. Madhavan, “Evaluation Of A Method For Detection Of Both Metallo Betalactamase (Mbl) And Efflux Production Using Carbonyl Cyanide 3- Chlorophenylhydrazone (Cccp)±Combination Method Among Pseudomonas Aeruginosa Isolated From Clinical Specimens,” Int. J. Pharm. Pharm. Sci., vol. 8, no. 8, pp. 185–189, 2015. S. Neriyanuri, R. Raman, P. Rishi, K. Govindasamy, V. Ramprasad, and T. Sharma, “Prenatal genetic diagnosis of retinoblastoma – clinical correlates on follow-up,” Indian J. Ophthalmol., vol. 63, no. 9, p. 741, 2015. Rajalakshmy, J. Malathi, H. Madhavan, and J. Samuel, “Mebiolgel, a thermoreversible polymer as a scaffold for three dimensional culture of Huh7 cell line with improved hepatocyte differentiation marker expression and HCV replication,” Indian J. Med. Microbiol., vol. 33, no. 4, p. 554, 2015. R. Raman, K. Santhanam, L. Gella, B. Pal, and T. Sharma, “Morphological and functional outcomes following modified early treatment diabetic retinopathy study laser in diabetic macular edema,” Oman J. Ophthalmol., vol. 8, no. 2, p. 92, 2015. K. Saurabh, K. Sarkar, R. Roy, and P. Majumder, “Personal and practice profile of male and female ophthalmologists in India,” Indian J. Ophthalmol., vol. 63, no. 6, p. 482, 2015. T. Sharma, R. Raman, D. Damkondwar, and S. Neriyanuri, “Microperimetry biofeedback training in a patient with bilateral myopic macular degeneration with central scotoma,” Indian J. Ophthalmol., vol. 63, no. 6, p. 534, 2015.

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Sowmiya M, Malathi J, Swarnali S, Priya JP, Therese KL, Madhavan HN. A study on the characterization of Propionibacterium acnes isolated from ocular clinical specimens. Indian J Med Res. 2015 Oct;142(4):438- 49. doi: 10.4103/0971-5916.169209. S. Sreenivasan and S. Krishnakumar, “Synergistic Effect of Curcumin in Combination with Anticancer Agents in Human Retinoblastoma Cancer Cell Lines.,” Curr. Eye Res., vol. 40, no. 11, pp. 1153–65, 2015. N. Subramanian, J. R. Kanwar, P. K. Athalya, N. Janakiraman, V. Khetan, R. K. Kanwar, S. Eluchuri, and S. Krishnakumar, “EpCAM aptamer mediated cancer cell specific delivery of EpCAM siRNA using polymeric nanocomplex.,” J. Biomed. Sci., vol. 22, p. 4, 2015. M. S. Alam, N. Subramanian, K. Koka, and K. Subramanian, “Orbital angioleiomyoma: A rare orbital neoplasm.,” Orbit, vol. 35, no. 2, pp. 113–6, 2016. Thirumudi, U. Vetrivel, M. B, K. L. Therese, and H. N. Madhavan, “Insights on drug targeting of toxoplasma Gondii host invasion proteins: A review,” vol. 8, no. 3, pp. 52–57, 2015. N. Venkatesan, P. R. Deepa, V. Khetan, and S. Krishnakumar, “Computational and in vitro Investigation of miRNA-Gene Regulations in Retinoblastoma Pathogenesis: miRNA Mimics Strategy.,” Bioinform. Biol. Insights, vol. 9, pp. 89–101, 2015. Rajeswari Mahadevan,Rajni Rajan, Sheeba Swarna, And Prafulla Kuthe, “SiHy Prescribing Trends.” Contact Lens Spectrum Article Date: 4/1/2015. Beta M, Krishnakumar S, Elchuri SV, Salim B, Narayanan J. “A comparative fluorescent beacon-based method for serum microRNA quantification. Anal Sci. 2015;31(3):231-5. doi: 10.2116/analsci.31.231. N. Subramanian, J. R. Kanwar, B. Akilandeswari, R. K. Kanwar, V. Khetan, and S. Krishnakumar, “Chimeric nucleolin aptamer with survivin DNAzyme for cancer cell targeted delivery.,” Chem. Commun. (Camb)., vol. 51, no. 32, pp. 6940–3, Apr. 2015. Kaviarasan K, Jithu M, Arif Mulla M, Sharma T, Sivasankar S, Das UN, Angayarkanni N. “Low blood and vitreal BDNF, LXA4 and altered Th1/Th2 cytokine balance are potential risk factors for diabetic retinopathy”. Metabolism. 2015 Sep;64(9):958-66. doi: 10.1016/j.metabol.2015.04.005. Epub 2015 May 1. M. K. Parthasarathy and M. Bhende, “Effect of ocular magnification on macular measurements made using spectral domain optical coherence tomography.,” Indian J. Ophthalmol., vol. 63, no. 5, pp. 427–31, May 2015. N. Singh, S. Krishnakumar, R. K. Kanwar, C. H. A. Cheung, and J. R. Kanwar, “Clinical aspects for survivin: a crucial molecule for targeting drug-resistant cancers.,” Drug Discov. Today, vol. 20, no. 5, pp. 578–87, May 2015. V. V. Jaichandran, R. Raman, L. Gella, and T. Sharma, “Local Anesthetic Agents for Vitreoretinal Surgery,” Ophthalmology, vol. 122, no. 5, pp. 1030–1033, May 2015. L. Gella, R. Raman, V. Kulothungan, S. S. S. Pal, S. Ganesan, T. Sharma R. Raman, S. S. S. Pal, G. Laxmi, and M. Gupta, et. al “Impairment of Colour Vision in Diabetes with No Retinopathy: Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetics Study (SNDREAMS- II, Report 3),” PLoS One, vol. 10, no. 6, p. e0129391, Jun. 2015. L. Vijaya, R. Asokan, M. Panday, N. S. Choudhari, S. Ve Ramesh, L. Velumuri, and R. George, “Six-Year Incidence and Baseline Risk Factors for Pseudoexfoliation in a South Indian Population,” Ophthalmology, vol. 122, no. 6, pp. 1158–1164, Jun. 2015.

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D. Bhavsar, K. Subramanian, S. Sethuraman, and U. M. Krishnan, “Management of retinoblastoma: opportunities and challenges.,” Drug Deliv., pp. 1–9, Jul. 2015. Z. Li, R. R. Allingham, M. Nakano, L. Jia, Y. Chen, Y. Ikeda, B. Mani, L.-J. Chen, C. Kee, D. F. Garway- Heath, S. Sripriya, et.al , “A common variant near TGFBR3 is associated with primary open angle glaucoma.,” Hum. Mol. Genet., vol. 24, no. 13, pp. 3880–92, Jul. 2015. S. Srilekha, T. Arokiasamy, N. N. Srikrupa, V. Umashankar, S. Meenakshi, P. Sen, S. Kapur, N. Soumittra, Y. Chinchore, A. Mitra, et.al , “Homozygosity Mapping in Leber Congenital Amaurosis and Autosomal Recessive Retinitis Pigmentosa in South Indian Families,” PLoS One, vol. 10, no. 7, p. e0131679, Jul. 2015. L. Gella, R. Raman, S. S. Pal, S. Ganesan, and T. Sharma, “Fixation characteristics among subjects with diabetes: SN-DREAMS II, Report No. 5.,” Can. J. Ophthalmol., vol. 50, no. 4, pp. 302–9, Aug. 2015. L. Gella, R. Raman, S. S. Pal, S. Ganesan, and T. Sharma, “Incidence, Progression, and Associated Risk Factors of Posterior Vitreous Detachment in Type 2 Diabetes Mellitus: Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetic Study (SN-DREAMS II, Report No. 7).,” Semin. Ophthalmol., pp. 1–7, Aug. 2015. Rishi, P. Rishi, B. Appukuttan, J. Walinjkar, J. Biswas, and T. Sharma, “Sympathetic ophthalmitis following vitreoretinal surgery: Does antecedent trauma make a difference?,” Indian J. Ophthalmol., vol. 63, no. 9, pp. 692–8, Sep. 2015. K. Kaviarasan, M. Jithu, M. Arif Mulla, T. Sharma, S. Sivasankar, U. N. Das, and N. Angayarkanni, “Low blood and vitreal BDNF, LXA4 and altered Th1/Th2 cytokine balance are potential risk factors for diabetic retinopathy.,” Metabolism., vol. 64, no. 9, pp. 958–66, Sep. 2015. N. G. Maremanda, K. Roy, R. K. Kanwar, V. Shyamsundar, V. Ramshankar, A. Krishnamurthy, S. Krishnakumar, and J. R. Kanwar, “Quick chip assay using locked nucleic acid modified epithelial cell adhesion molecule and nucleolin aptamers for the capture of circulating tumor cells.,” Biomicrofluidics, vol. 9, no. 5, p. 054110, Sep. 2015. B. Mukherjee, J. Kadaskar, O. Priyadarshini, S. Krishnakumar, and J. Biswas, “Angiolymphoid Hyperplasia with Eosinophilia of the Orbit and Adnexa.,” Ocul. Oncol. Pathol., vol. 2, no. 1, pp. 40–7, Sep. 2015. Lakshmipathy D1, Kulandai LT2, Ramasubban G1, Hajib Narahari Rao M1, Rathinam S3, Narasimhan M4. “Nested reverse transcriptase-polymerase chain reactions targeting the messenger RNA of icl2, hspx, and rRNAP1 genes to detect viable Mycobacterium tuberculosis directly from clinical specimens. Int J Mycobacteriol. 2015 Dec;4(4):312-7. doi: 10.1016/j.ijmyco.2015.09.005. Epub 2015 Oct 1. Aditya Verma, Jyotirmay Biswas, Dhanurekha Lakshmipathy, Lily Therese Kulandai Gayathri Ramasubban. “Detection of Mycobacterium tuberculosis with nested polymerase chain reaction analysis in enucleated eye ball in Eales' disease”. Int Ophthalmol 2015 DOI 10.1007/s10792-015-0144-9. J. Samuel, N. Singh, J. R. Kanwar, S. Krishnakumar, and R. K. Kanwar, “Upregulation of sodium iodide symporter (NIS) protein expression by an innate immunity component: Promising potential for targeting radiosensitive retinoblastoma.,” Exp. Eye Res., vol. 139, pp. 108–14, Oct. 2015 S. Palla, J. Biswas, and C. K. Nagesha, “Efficacy of Ozurdex implant in treatment of noninfectious intermediate uveitis.,” Indian J. Ophthalmol., vol. 63, no. 10, pp. 767–70, Oct. 2015. Shrirao N, Mukherjee B, Krishnakumar S, Biswas J. Cholesterol granuloma: a case series & review of literature. Graefes Arch Clin Exp Ophthalmol. 2015 Oct 6.

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Gondchawar, J. Biswas, S. Murali, andL. M. P. Eawaran, “A case of herpes simplex keratouveitis diagnosed by real time polymerase chain reaction.,” Indian J. Ophthalmol., vol. 63, no. 11, pp. 854–5, Nov. 2015. M. K. Janani, J. Malathi, M. Rela, M. Farouk, J. Padmapriya, and H. N. Madhavan, “Genotypic Detection of Epstein Barr Virus in Pediatric Transplant Recipients From India.,” Indian Pediatr., vol. 52, no. 11, pp. 946–50, Nov. 2015. M. Sangeetha, P. R. Deepa, P. Rishi, V. Khetan, and S. Krishnakumar, “Global gene deregulations in FASN silenced retinoblastoma cancer cells: molecular and clinico-pathological correlations.,” J. Cell. Biochem., vol. 116, no. 11, pp. 2676–94, Nov. 2015. Pandey, S. Balekudaru, R. George, V. Lingam, and M. Panday, “Surgical Management of Glaucoma in Sturge-Weber Syndrome.” Glaucoma: Open Access Received date: September 15, 2015; Accepted date: October 31, 2015; Published date: November 10, 2015 H. Sharma, S. Sudharshan, L. Therese, M. Agarwal, and J. Biswas, “Candida albicans scleral abscess in a HIV-positive patient and its successful resolution with antifungal therapy-a first case report.,” J. Ophthalmic Inflamm. Infect., vol. 6, no. 1, p. 24, Dec. 2015. S. Ambika, M. Balasubramanian, L. Theresa, A. Veeraputhiran, and D. Arjundas, “Aquaporin 4 antibody [NMO Ab] status in patients with severe optic neuritis in India.,” Int. Ophthalmol., vol. 35, no. 6, pp. 801–6, Dec. 2015. D. Lakshmipathy, L. T. Kulandai, G. Ramasubban, M. Hajib Narahari Rao, S. Rathinam, and M. Narasimhan, “Nested reverse transcriptase-polymerase chain reactions targeting the messenger RNA of icl2, hspx, and rRNAP1 genes to detect viable Mycobacterium tuberculosis directly from clinical specimens.,” Int. J. mycobacteriology, vol. 4, no. 4, pp. 312–7, Dec. 2015. B. Mukherjee, O. Priyadarshini, S. Ramasubramanian, and S. Agarkar, “Iatrogenic Injury to Medial Rectus After Endoscopic Sinus Surgery.,” Indian J. Otolaryngol. Head Neck Surg., vol. 67, no. 4, pp. 394–402, Dec. 2015. Murugan N, Malathi J, Umashankar V, Madhavan HN. “Resistome and pathogenomics of multidrug resistant (MDR) Pseudomonas aeruginosa VRFPA03, VRFPA05 recovered from alkaline chemical keratitis and post-operative endophthalmitis patient”. Gene. 2016 Mar 1;578(1):105-11. doi: 10.1016/j.gene.2015.12.022. Epub 2015 Dec 10. J. J. González-López, A. Lavric, P. Dutta Majumder, N. Bansal, J. Biswas, C. Pavesio, and R. Agrawal, “Bilateral Posterior Scleritis: Analysis of 18 Cases from a Large Cohort of Posterior Scleritis.,” Ocul. Immunol. Inflamm., vol. 24, no. 1, pp. 16–23, 2016. Lavric, J. J. Gonzalez-Lopez, P. D. Majumder, N. Bansal, J. Biswas, C. Pavesio, and R. Agrawal, “Posterior Scleritis: Analysis of Epidemiology, Clinical Factors, and Risk of Recurrence in a Cohort of 114 Patients.,” Ocul. Immunol. Inflamm., vol. 24, no. 1, pp. 6–15, 2016. G. Narayanan, R. Saravanan, M. Bharathselvi, J. Biswas, and K. N. Sulochana, “Localization of Human Copper Transporter 1 in the Eye and its Role in Eales Disease.,” Ocul. Immunol. Inflamm., pp. 1–6, Jan. 2016. Kanwar JR, Kamalapuram SK, Krishnakumar S, Kanwar RK. Multimodal iron oxide (Fe(3)O(4))- “ saturated lactoferrin nanocapsules as nanotheranostics for real-time imaging and breast cancer therapy of claudin-low, triple-negative” (ER(-)/PR(-)/HER2(-)). Nanomedicine (Lond). 2016 Jan 20.

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Kalmodia S, Vandhana S, Tejaswini Rama BR, Jayashree B, Sreenivasan Seethalakshmi T, Umashankar V, Yang W, Barrow CJ, Krishnakumar S, Elchuri SV.'Bio-conjugation of antioxidant peptide on surface- modified gold nanoparticles: a novel approach to enhance the radical scavenging property in cancer cell'. Cancer Nanotechnol. 2016;7:1. Epub 2016 Feb 9. N. Shrirao, B. Mukherjee, S. Krishnakumar, and J. Biswas, “Cholesterol granuloma: a case series & review of literature.,” Graefe's Arch. Clin. Exp. Ophthalmol. Albr. von Graefes Arch. für Klin. und Exp. Ophthalmol., vol. 254, no. 1, pp. 185–8, Jan. 2016. E. Rishi, M. V Govindarajan, J. Biswas, M. Agarwal, S. Sudharshan, and P. Rishi, “Syphilitic uveitis as the presenting feature of HIV.,” Indian J. Ophthalmol., vol. 64, no. 2, pp. 149–50, Feb. 2016. N. Venkatesan, J. Kanwar, P. R. Deepa, V. Khetan, T. M. Crowley, R. Raguraman, G. Sugneswari, P. Rishi, V. Natarajan, J. Biswas, and S. Krishnakumar, “Clinico-Pathological Association of Delineated miRNAs in Uveal Melanoma with Monosomy 3/Disomy 3 Chromosomal Aberrations.,” PLoS One, vol. 11, no. 1, p. e0146128, 2016. V. Gopakumar, Nivedita Chatterjee, Sowmya Parameswaran, Subramanian Nirmala , Subramanian Krishnakumar, “In vitro transdifferentiation of human skin keratinocytes to corneal epithelial cells” Cytotherapy, 2016; 18: 673–685 T. Das, A. Aurora, J. Chhablani, A. Giridhar, A. Kumar, R. Raman, M. Nagpal, R. Narayanan, S. Natarajan, K. Ramasamay, M. Tyagi, and L. Verma, “Evidence-based review of diabetic macular edema management: Consensus statement on Indian treatment guidelines,” Indian J. Ophthalmol., vol. 64, no. 1, p. 14, 2016. L. Gella, R. Raman, and T. Sharma, “Quantitative spectral domain optical coherence tomography thickness parameters in type II diabetes,” Oman J. Ophthalmol., vol. 9, no. 1, p. 32, 2016. P. Patil-Chhablani, S. Murthy, and M. Swaminathan, “Ophthalmic profile and systemic features of pediatric facial nerve palsy,” J. Eye Sci., vol. 1, no. 1, 2016. R. Raman, L. Gella, S. Srinivasan, and T. Sharma, “Diabetic retinopathy: An epidemic at home and around the world,” Indian J. Ophthalmol., vol. 64, no. 1, p. 69, 2016. Bindu Salim, Swapna Merlin David, Madhu Beta, Janakiraman Narayanan, Subramanian Krishnakumar and Thalakkotur Lazar Mathew “PMMA Platform Based Micro Fluidic Mixer for the Detection of MicroRNA- 18a from Retinoblastoma Serum”, Journal of Analytical & Bio-analytical Techniques, 2015, Vol:6, Issue 4, 1000258. N. Subramanian, B. Akilandeswari, A. Bhutra, M. Alameen, U. Vetrivel, V. Khetan, R. K. Kanwar, J. R. Kanwar, S. Krishnakumar, et. al “Targeting CD44, ABCG2 and CD133 markers using aptamers: in silico analysis of CD133 extracellular domain 2 and its aptamer,” RSC Adv., vol. 6, no. 38, pp. 32115–32123, 2016. N. Shrirao, B. Mukherjee, S. Krishnakumar, and J. Biswas, “Cholesterol granuloma: a case series & review of literature.,” Graefe's Arch. Clin. Exp. Ophthalmol. Albr. von Graefes Arch. für Klin. und Exp. Ophthalmol., vol. 254, no. 1, pp. 185–8, Jan. 2016. G. Narayanan, R. Saravanan, M. Bharathselvi, J. Biswas, and K. N. Sulochana, “Localization of Human Copper Transporter 1 in the Eye and its Role in Eales Disease,” Ocul. Immunol. Inflamm., pp. 1–6, Jan. 2016. P. K. Athyala, J. R. Kanwar, M. Alameen, R. K. Kanwar, S. Krishnakumar, J. Watson, U. Vetrivel, and J. Narayanan, “Probing the biophysical interaction between Neocarzinostatin toxin and EpCAM RNA aptamer.,” Biochem. Biophys. Res. Commun., vol. 469, no. 2, pp. 257–62, Jan. 2016.

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Vimalin Jeyalatha, Malathi Jambulingam, Madhavan N Hajib. Stepwise Protocol for Cytospin-enhanced Smearing for Scraped Corneal Epithelial Cells. Applied Immunohistochemistry Molecular Morphology.2016;24:71-7 R. Roy and K. Saurabh, “Bilateral acute ophthalmic artery occlusion in a case of giant cell arteritis.,” Indian J. Med. Res., vol. 143, no. 1, pp. 116–7, Jan. 2016. P. K. Shah, S. Sripriya, V. Narendran, and A. J. Pandian, “Prenatal genetic diagnosis of retinoblastoma and report of RB1 gene mutation from India,” Ophthalmic Genet., pp. 1–4, Feb. 2016. E. Rishi, M. V Govindarajan, J. Biswas, M. Agarwal, S. Sudharshan, and P. Rishi, “Syphilitic uveitis as the presenting feature of HIV.,” Indian J. Ophthalmol., vol. 64, no. 2, pp. 149–50, Feb. 2016. Neha Goel, Atul Kumar, Mahesh P Shanmugam, Muna Bhende, Raja Narayanan, Hidetaka Matsumoto, “Thinking Beyond Wet Age-Related Macular Degeneration,” Delhi J. Ophthalmol., vol. 26, no. 3, pp. 210–217, Mar. 2016. N. Murugan, J. Malathi, V. Umashankar, and H. N. Madhavan, “Resistome and pathogenomics of multidrug resistant (MDR) Pseudomonas aeruginosa VRFPA03, VRFPA05 recovered from alkaline chemical keratitis and post-operative endophthalmitis patient.,” Gene, vol. 578, no. 1, pp. 105–11, Mar. 2016. BOOK PUBLISHED: “Uveitis: An Update” Biswas J, Parthopratim Dutta Majumder, by Springer, 2015. “Diabetic Retinopathy Management Manual 2015” Taraprasad Das, Rajiv Raman, R Rajalakshmi, Padmaja K Rani, by National Programme for Control of Blindness. CHAPTERS IN BOOKS PUBLISHED: Angayarkanni N, K. Coral, SR. Bharathidevi, “Toxicology” in Dr.Santhanam'S Text book of occupational optometry , First Edition, Sankara Nethralaya , 2015 pp 219-39 Tarun Sharma, Rajiv Raman “Microincision Vitrectomy Surgery: The Answer to Manage Complications of Proliferative Diabetic Retinopathy” in Diabetes Clinical Case Series - 1”, by Jaypee Brothers Meenakshi S, Srikanth R “Ophthalmology” in Partha's Management Protocols in Pediatric and Adolescent Practice by Jaypee Brothers. COMPLETED PROJECTS: To train and develop infrastructure for Molecular Ophthalmic Pathology and Rapid Diagnosis of Ocular Infections in an Ophthalmic Institute in Assam [Dr H N Madhavan] Application of next generation sequencing technique to determine the whole genome sequence of laboratory isolates of Enterococccus feaclias, Pseudomonas aeruginosa, Bacillus cereus (Both sensitive and resistant strains) and application of bioinformatics approach to identify the vulnerable area of drug targets in the genome [Dr J Malathi] Investigating the therapeutic potential of Lysyl Oxidase propeptide in angiogenesis and tumorogenesis [Dr K Coral] Contact lens wear induced changes in Keratoconus patients at the level of redox status inflammatory cytokines and collagen cross linking [Dr N Angayarkanni] Anti angiogenic potential of the plant derived polyphenols, Elagic, Gallic, Chebulagic and Chebulinic acids: an in vitro study in retinal endothelial cells [Dr N Angayarkanni]

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Molecular modelling and docking simulation studies of functional domains of Toxoplasma gondii RON4, RON2 & RON5 to understand the moving junction complex formation towards design of novel peptide and chemical inhibitors and validation through pilot “in vitro” studies [Dr V Umashankar] Development of modulators of ornithine decarboxylase (ODC) for the therapeutic application in retinoblastoma [Dr V Umashankar] Regulation of SNARE exocytotic machinery under physiological and pathological conditions of diabetes and obesity [Dr C Subbulakshmi] Biomarkers pattern discovery of graded changes in the opacity of human lens in age-onset cataract: a proteomic approach [Dr Ananthkumar Badrinath] Molecular genetic analysis of ocular developmental anomalies in Indian population [Dr S. Sripriya] To investigate the cross-talk between oxidative stress and cellular methylation processes and dissect the functional role of epigenetically silenced gene in RB [Dr J Biswas] To validate a panel of differentially expressed miRNAs from RB serum profile and correlate clinicopathologically [Dr S Krishnakumar] To investigate the role of tumor microenvironment in RB progression [Dr S Krishnakumar] Locked nucleic acid modified aptamer-siRNA Chimeric conjugates for improved chemosensitivity and eradication of cancer stem cells [Dr S Krishnakumar] Identification of potential molecular inhibitors of all catalytic domains of Fatty Acid Synthase (FASN) at the enzyme activity and gene expression level [Dr V Umashankar] CR -5265 2-Week dispensing cross-over evaluation of marketed silicone hydrogel contact lenses in an Indian population [Dr M Rajeswari]

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ONGOING PROJECTS Multicenter Phase II Study for International Intraocular Retinoblastoma Classification Groups B, C & D tumuors Treated with Carboplatin - Etoposide, Vincristine, and Cyclosporine - Focal Therapy Multimodality Protocol [Dr Vikas Khetan] Study to observe the effectiveness and safety of Lucentis through individualized patient treatment and Associated outcomes [Dr Tarun Sharma] A 12-month, phase III, randomized, visual acuity assessor-masked, multicenter study assessing the efficacy and safety of ranibizumab 0.5mg in treat and extend regimen compared to monthly regimen, in patients with neovascular age-related macular degeneration [Dr Muna Bhende] A 12-month, phase III, randomized, double-masked, multicenter, active-controlled study to evaluate the efficacy and safety of two individualized regimens of 0.5 mg ranibizumab vs. verteporfin PDT in patients with visual impairment due to choroidal neovascularization secondary to pathologic myopia (Brilliance) [Dr Tarun Sharma] A Prospective, open label study to evaluate the Intraocular Pressure lowering effect of 0.15% w/v Forskolin solution in patients with Ocular hypertension or mild open angle glaucoma [Dr Ronnie Jacob George] Normative data collection for Oculomotor functions using eye tracking technology in accordance with conventional method [Dr Ronnie Jacob George] A Multi-Center Controlled, Safety and Efficacy Study of a Fluocinolone Acetonide Intravitreal (FAI) Insert in Subjects with Chronic Non-Infectious Uveitis Affecting the Posterior Segment of the Eye [Dr J Biswas] CR:5201 Echo Ionic Silicone Hydrogel 6-month Extended Wear Investigation [Dr M Rajeswari] A Phase 2/3, Randomized, Double-Masked, Sham controlled Trial of QPI-1007 Delivered by Single or Multi- Dose intra vitreal injection(s) to subjects with Acute No-Arteric Anterior Ischemic Optic Neuropathy (NAION) [Dr S Ambika] A multi-center, open-label, observational study to evaluate the efficacy and safety of intravitreal injections (IVI) of Ranibizumab in patients with visual impairment due to Diabetic Macular Edema(DME) [Dr Mohammad Arif Mulla] Development of Low Cost Sweep VEP system [Dr Ronnie Jacob George] Effect of riboflavin / UVA in treating patients with infectious keratitis: A pilot study on human subjects [Dr Prema Padmanabhan] An in-vitro study to understand the effect of different concentrations of lignocaine on the fibroblasts growth. [Dr H N Madhavan] Development of Anti-Fibrotic agents for potential use in the Glaucoma filtration surgery to prevent scar formation in cultured human scleral Chondrocytes and Tenons Fibroblast [Dr K Coral] Peripheral Blood Gene expression profiling in Eales Disease [Dr K Coral] Understanding the effect of Adiponectin mediated signaling pathways on retinal degeneration using human retinal explant culture for designing efficient neuroprotective agent [Dr C Subbulakshmi] Regulation of Lysyl oxidase expression in lens epithelial cells and trabecular endothelium [Dr N Angayarkanni]

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Corneal Endothelial Function in Health and Disease [Dr Prema Padmanabhan] CTR1 (Copper transporter 1) as a therapeutic target for angiogenesis; understanding its cellular and molecular signaling in retinal angiogenesis [Dr S R Bharathi Devi] Development of therapeutic molecules for diabetic retinopathy from studies on structure/function relationship of PON2 by cloning [Dr S R Bharathi Devi] To elucidate the role of cystathionine beta synthase enzyme and hydrogen sulphide in retinal cells exposed to thiol compounds [Dr S R Bharathi Devi] Insilco drug target identification in Chlamydial species through systems biology and molecular modelling approaches pertaining to the development of potential drug molecules [Dr V Umashankar] Design and development of novel Anti-Angiogenic molecules by targeting polysaccharide binding domain of Carbonic Anhydrase IX through structural bioinformatics methods and studies on cell culture models [Dr V Umashankar] Intervention of ciliopathy genes in the molecular pathology of BBS in Indian population [Dr S Sripriya] Whole exome sequencing in Leber congenital amarousis (LCA) to identify novel gene(s) [Dr N Soumittra] Proteomics based identification and Validation of urinary Biomarkers for Age-related Macular Degeneration and development of sensor [Dr J Biswas] miRNA in Retinoblastoma progression, biomarkers and novel Aptamer-miRNA therapeutics [Dr S Krishnakumar] Differentiation and characterisation of dental pulp cells to corneal epithelial cells [Dr S. Krishnakumar] Use of Aptamer to increase the efficacy of HMGA2 targeted therapy in Retinoblastoma [Dr S Krishnakumar] Exosomal microRNA as biomarkers of early and late stage Retinoblastoma. [Dr S Krishnakumar] Proteomics and phosphoproteomics by mass spectrometry and flow cytometry in Retinoblastoma [Dr Sailaja Elchuri] To Engineer a Aptamer-siRNA chimeric conjugates for targeting epithelial cancers [Dr Sailaja Elchuri] miRNA clusters in retinal cytokine producing glia which control inflammation during HIV 1 Tat exposure: Implications for immune recovery uveitis. [Dr Nivedita Chatterjee] Investigating the effects of HIV- 1 proteins in retinal blood brain barrier degeneration [Dr Nivedita Chatterjee] Identification of Ocular Inflammatory mediators in Steven Johnsons Syndrome. [Dr Srividya. G] Deciphering the role of LIN28B in retinoblastoma [Dr S. Krishnakumar] Study on the efficacy of Ataluren to promote premature termination codon read-through in RDH12 (c.38C>A) nonsense mutation [Dr Sowmya Parameswaran]

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PARTICIPATION IN THE CONFERENCE Dr J Biswas and Dr Vikas Khetan participated in the 30th Asia-Pacific Academy of Ophthalmology Congress at China from 1st to 4th April 2015. Dr Biswas made presentations on “Live intraocular parasites causing uveitis”, “Eales' disease” and “Clinic pathological correlations in lid & lesions” and Dr Vikas Khetan gave a presentation on “Adult onset retinoblastoma” Dr Srikanth R participated in the Strabismus and Pediatric Ophthalmological Society of India – midterm conference held at Ludhiana on 5th April 2015 and gave presentations on “Small Angle strabismus”, “Ametropic Amblopia”. Dr Pukhraj Rishi, Dr Meena Lakshmipathy and Dr Shweta S Agarwal attended the Delhi Ophthalmology Society Annual Conference, New Delhi from 10th to 12th April 2015. Dr Pukhraj Rishi made a presentation on “Newer advances in treatment of intraocular tumors; Dr Meena Lakshmipathy delivered a guest lecture on “Bacterial Keratitis” and Dr Shweta S Agarwal gave a guest lecture on “Vernal Conjunctivitis”. Dr V Umashankar delivered an invited talk on “Ophthalmic Research and Bioinformatics” at The Second INAE-NATF Workshop on “Technology and Health-Care” at National Institute of Advanced Studies (NIAS), IISc Campus, Bangalore conducted from 15th to17th April 2015. Dr Muna Bhende participated in the Vitromacular Interface Problems II, Bengaluru, on 26th April 2015 and made a presentation on “Management of recurrent macular hole” Dr Rajiv Raman attended the Annual Meeting of the Association for Research in Vision and Ophthalmology, Denver, USA, from 3rd to 7th May, 2015 and made a poster presentation on “Genotype- Phenotype correlation in X-linked Retinoschisis” Dr Biswas J attended the Granulomatous Uveitis Workshop at Philippines, from 15th to 17th May 2015 and made a presentation on “Multifocal Serpiginoid Choroiditis” Dr Muna Bhende and Dr Pramod Bhende attended the “Celebrate Retina Celebrate Life” meet at Aditya Jyot Eye Hospital Pvt. Ltd, Mumbai, from 15th to 17th May 2015. Dr Muna Bhende made a presentation on “Swept Source OCT” and Dr Pramod Bhende made presentations on “Vitrectomy for myopic fovealschisis” and “Lens sparing vitrectomy for ROP”. Dr Sripriya Krishnamurthy and Dr Ronnie George attended the World Glaucoma Congress at Hong Kong, from 06th to 09th June 2015. Dr Sripriya Krishnamoorthy gave a presentation on “Incidence of secondary ocular hypertension following nucleus drop in cataract surgery in a training centre” and Dr Ronnie George made presentations on “Anterior segment dysgenesis”, “Lesser form population based study in India”, “Progress of glaucoma from India” and “Mechanical laser in malignant glaucoma”. Dr Pukhraj Rishi attended the International Society of Ocular Oncology Meeting held at Paris, France from 15th to 19th June 2015, and gave poster presentations on “Intra-arterial chemotherapy for retinoblastoma: first year results from India” and “Presentation of posteriorly-located, medium-sized choroiodal melanoma with extraocular extension in a 42-year-old Asian Indian lady” and oral presentation on “Intravitreal chemotherapy for recurrent or refractory vitreous seeds in eyes with retinoblastoma” Dr Vikas Khetan, Dr Trupti Sudhir Patil participated in the Telangana Ophthalmic Society Meeting at Karimnagar, on 21st June 2015. Dr Vikas Khetan made a presentation on “Management of Intraocular Retinoblastoma Group A to C Classification”; DrTrupti Sudhir Patil on “Intraocular pressure measurement post refractive surgery and its correlation to amount of corneal tissue ablated ” Dr Amala Elizabeth George participated in the Bangalore Ophthalmic Society Meeting at Bangalore, on 22nd June 2015 and gave a presentation on “Decoding Uveitis Workup”.

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Dr N Soumittra delivered an invited talk entitled, “Molecular Profiling of Leber Congetinal Amaurosis on an Indian cohort” in the CME on Impact of Genetics in Medicine held at the Centre for Medical Genetics, Chennai on 4th July 2015. Dr K Lily Therese has been nominated as a team member for approving “BSL3 laboratory upgradation” for Bacteriology Department, National Institute for Research in Tuberculosis Centre (NIRT), Chennai on 8th July 2015. The Department of Cornea of Sankara Nethralaya organized the 2nd meeting of Ocular Surface & Keratoprothesis (OSKON) 2015 from 10th to 12th July 2015. The focus was on the ocular surface disorders and keratoprosthesis. International and national experts shared their experiences in their areas of expertise and avenues for further research were identified. The meeting received a very warm response with the number of participants being around 250. Dr T S Surendran, Dr Bipasha Mukherjee, Dr Kavitha Kalaivani, Dr Sumita Agarkar, Dr Pukhraj Rishi, Dr Parveen Sen and Dr Mona Kurana participated in the Annual Meeting of Tamil Nadu Ophthalmic Association at Madurai from 24th to 26th July 2015. Dr Surendran made presentations on “Coping with complications and re-surgeries”; “Managing an institution” and “Use of Botulinium toxin a injection for strabismus”; Dr Bipasha Mukherjee on “Vascular lesions of the orbit”, “Orbital trauma” and “Vascular lesions of the orbit”; Dr Kavitha Kalaivani on “The perpetual dilemma”, “Uveitic cataracts in children” & “Traumatic cataract”; Dr Sumita Agarkar gave presentations on “Pediatric cataracts with associated lenticular anomalies” & “Difficult scenario in concomitant strabismus”; Dr Pukhraj Rishi on “Fundus Auto fluorescence - Ebony & Ivory truths”; DrParveen Sen on “Electrophysiology - The telling undercurrents” and Dr Mona Kurana on “Medical Therapy for Glaucoma-Practical Tips”. Dr Krishnakumar S, Dr Angayarkanni N, Dr S Sripriya and Mr Ravikanth Danda attended the Indian Eye Research Group (IERG) ARVO Conference at L.V. Prasad Eye Institute (LVPEI), Hyderabad from 25th to 26th July 2015. Dr S Krishnakumar gave a lecture on 'Aptamer chimera targeting EpCAM'; Dr Angayarkanni delivered an invited talk on “Low levels of BDNF in Diabetic retinopathy” and made poster presentations on “The effect of phyto-compounds on the mesenchymal changes in RPE” and “Brain derived neurotrophic factor and its relevance in diabetic retinopathy” and. Dr Sripriya delivered an invited talk on “Targeted next generation sequencing in ocular developmental anomalies”. Dr Pramod S Bhende and Dr Chetan Rao participated in the Asia Pacific Vitreoretina Society Meeting from 31st July to 2nd August 2015. Dr Pramod Bhende made a presentation on “ROP-Laser treatment – Tricks and pitfalls”, Poster presentations on “Vitrectomy for myopic tractional maculopathy (MTM) – intraopertive findings, functional and anatomical outcome” and “Displaced trans-scleral fixated intraocular lens – Re-fixation, anatomical and functional outcome”; Dr Chetan Rao made a poster presentation on “Combined sclera suture fixated intra-ocular lens and parsplana vitrectomy for ocular trauma- A study of functional and anatomical outcome”, and a paper presentation on “Structural and functional characterization of Benign Flecked retina on multimodal imaging”. Dr S Krishnakumar gave a keynote address on “Current Trends in Translational Medicine” at the Indo US Meet held at Sathyabama University, Chennai, on 1st August, 2015. Dr Prema Padmanabhan participated in the BMJ Class, from 3rd to 4th August 2015 at West Bengal and made presentations on “Keratoconus – A familiar Stranger” and “Fuchs Endothelial Dystrophy – A fresh perspective on an old disease”. Dr Tarun Sharma attended the BMJ Master class in Ophthalmology 2015 on 6th August 2015 at Pune and gave a presentation on “Macula Potpourri”. Dr N Angayarkanni delivered a guest lecture on “RPE in health and Diseases” in the first Annual Advanced Lecture Series in Ocular Pharmacology held at Siddaganga Institute of Technology (SIT), Tumkur, Karnataka along with our cornea team on 8th August 2015.

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Dr Muna P Bhende and Dr Pukhraj Rishi participated in the 9th Indian AMD Congress at New Delhi on 8th & 9th August 2015. Dr Pukhraj Rishi gave a présentation on 'An interesting case of a choroidal cleft'. Dr Vathsalya Vijay participated in the Curbside Clinix CME held at Narayana Nethralaya, Bangalore, on 9th August 2015 and gave a paper presentation on “Combined Radiological and Surgical Intervention for Peri-orbital AV Malformation”. Dr N Angayarkanni delivered a guest lecture on “Basic science into clinical practice” in ESO's International Vision Science and Optometry Conference (EIVOC) held at Confluence Banquets and Resorts, Mamallapuram on 15th August 2015. Dr Rajiv Raman attended the International Laser Society meet at Indore, on 21st August 2015 and gave presentations on “Lasers for Diabetic macular edema”, “Micropulse laser” and “NAVILAS”. Dr J Narayanan attended the workshop organized by NPMASS Display Cum Demo Exhibition held at Bangalore on 22nd August 2015. Dr K Lily Therese and other Sankara Nethralaya faculty attended the CME programme “Cataract Catalyst” conducted at Hayatt Regency, Chennai on 23rd August 2015. Dr Rajiv Raman participated in the Indore Ophthalmic Association Retina Update meet on 23rd August 2015 and made presentations on “DME management guidelines” and “Preferred practice pattern in intravitreal injections”. Dr Tarun Sharma attended the ARVO Conference Diabetic Retinopathy – Battling the Global Epidemic from 27th to 28th August 2015 Dr Sumita Agarkar and Dr Rajiv Raman participated in the Focus Annual Meeting of Bombay Ophthalmologists' Association at Mumbai on 30th August 2015. Presentations on “Evaluation of special children” and “Factors affecting surgical outcomes” by Dr Sumita Agarkar and “Diabetic macular edema & treatment guidelines” by Dr Rajiv Raman were made. Dr Sumita Agarkar participated in the 3rd World Congress of Paediatric Ophthalmology and Strabismus at Barcelona, Spain, from 3rd to 8th September2015, and gave presentations on “Surgery in myasthenia gravis” and “Effect of lens sparing vitrectomy on myopia children after cataract surgery”. Dr Prema Padmanabhan and Dr Sudhir R R participated in the EuCornea Conference at Spain from 4th to 5th September 2015. Dr Prema Padmanabhan gave a presentation on “Corneal Collagen Cross-linking (CXL) comparison of response in pediatric and adult keratoconic patients” and made a poster presentation on “Co-existing keratoconus and Fuchs Endothelial corneal dystrophy (FECD): Challenges in diagnosis and management”. Dr Sudhir made a poster presentation on “Changes in corneal thickness after dilatation”, and presented a paper entitled “Long term results of collagen cross linking (CXL) for progressive keratoconus in pediatric age group”. Dr Prema Padmanabhan and Dr Sudhir R R attended the European Society of Cataract & Refractive Surgeons Meet at Spain from 5th to 9th September 2015. Dr Prema Padmanabhan made poster presentations on “Collagen Cross Linking (CXL) for progressive keratoconus: long term results and the impact of cone location and magnitude” and “Diagnostic characteristics of post-LASIK keratectasia: a proposed scoring system” and Dr Sudhir R R made presentations on “Fish-mouth compression suture in the management of corneal burn due to Phacoemulsification” and “Collagen cross linking: comparison of results using iso-osmolar and hypo-osmolar 0.1% riboflavin solution for the treatment of progressive keratoconus”. Dr Sumita Agarkar participated in the Andhra Pradesh Ophthalmic Society Meeting at Tirupati on 12th September 2015 and gave a presentation on “Management of esotropia in Children”.

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Dr Muna P Bhende participated in the 15th EURETINA Congress in France, from 14th to 22nd September 2015 and made presentations on “Residual pockets of SRF after retinal reattachment - a case series” and “Pediatric giant retinal tears: Management outcomes” Dr Prema Padmanabhan participated in the Phaco-Refractive Meet at Bangalore on 19th & 20th September 2015, and made presentations on “Refractive Cataract Surgery”, “Tackling astigmatism during cataract surgery: Role of Toric IOL” Dr J Biswas attended the RIO GOH and delivered the Prof. E. T. Selvam Endowment Lecture on “Can ophthalmic pathology be interesting?” on 23rd September, 2015. Dr S Krishnakumar and Ms. Gayathree K participated in the International Angiogenesis Conference at SASTRA University, Thanjavur from 23rd to 25th September, 2015. Dr Krishnakumar delivered a lecture on 'Epcam and Angiogenesis in Retinoblastoma' and Ms. Gayathree presented a poster entitled “Hyperglycemia induces early growth response-1 (EGR1) in human diabetic retina mediating abnormal vascular changes in diabetic retinopathy“. Dr Dhanashree Ratra attended the Phacoret Conference at Puttaparthi, from 24th to 25th September, 2015 and presented papers entiled “Scleral fixated IOLs”, “Management of dislocated IOLs” and “Management of Supra-choroidal hemorrhage”. Dr Sudha K Genesh attended the 13th International Ocular Inflammation Society & Foster Ocular Immunology Society Meeting at San Francisco, USA from 24th to 27th September 2015. She was the Chair person and Moderator for the symposium on “Ocular TB in an endemic Country” and made a presentation on “Clinical manifestations of Ocular TB in endemic country”; gave a guest lecture on "Cataract surgery in pediatric uveitis” in the symposium of Pediatric Uveitis”. Dr S Sripriya and Dr Soumittra attended the Expert group meeting as a part of Asian Eye Genetics Consortium held at AIIMS, New Delhi on 26th September 2015. Dr J Malathi, Ms. M K Janani and Ms. M Vimalin Jeyalatha participated in the IAMM Conference in Clinical Microbiology ARISE – 2015 held at SRM University, Chennai from 28th & 29th September 2015. Dr Malathi delivered an invited lecture on “Next generation sequencing in diagnosis and research”; Ms. Janani made a poster presentation on “Novel Immune Regulatory Pathway Associated with Epstein Barr Virus (EBV) and the Recombinant EBV Protein Mediated Inflammation in Retinal Pigment Epithelium (ARPE-19)” and Ms. Vimalin Jeyalatha on “Response of Retinal Pigment Epithelial Cells towards Leptospiral recurrent Uveitis Antigens”. Mr. Ravikanth Danda received 'Travel fellowship grant' from DBT Government of India for attending HUPO Conference held at Vancouver, Canada from 27th September 2015 to 1st October 2015. Dr Priya Delampady attended the XXV Silver Jubilee Annual Conference of the Glaucoma Society of India, Mumbai from 2nd to 4th October 2015 and made a poster presentation on “Correlation of defect depth and defect pattern of Central Visual Fields with mGCC of OCT”. Dr Shantha B, Dr Ronnie George, and Dr Vineet Ratra participated in the Annual Meeting of Glaucoma Society of India 2015 at Mumbai, from 2nd to 4th October 2015. Dr Shantha made presentations on “The classical trabeculectomy technique”, “Easier & safer management of tube complications”, “Using the CIGTS study findings in clinical practice” and “Role of perimetry in the early diagnosis of glaucoma: FDP/SWAP flicker-defined-form perimetry”; Dr Ronnie George on “Very high IOP 7 painful blind eye what to do?”, “Taking charge and creating a plan”, “Framing research question”, “Epidemiology of angle closure disease in India”, “Imaging and its potential as a screening tool for angle closure”, “Management for early postoperative hypotony”, “How I was finding from the OHTS/EGPS study in treating ocular hypertension”, and “Eye tracking in perimetry”. Dr Vineet Ratra gave a presentation on “Cataract with POAG controlled with monotherapy combined surgery”.

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Dr Rajiv Raman participated in the CCDR Cycle National Expert Curriculum Review Meet on 9th October 2015 and made a presentation on “Developing Curriculum for DR training”. Dr Tarun Sharma Participated in the North Zone Ophthalmic Society Meet at Haryana from 9th to 11th October 2015 and gave a presentation on “Is it Wet AMD?” Dr H N Madhavan participated in the CME programme on 10th October 2015 held at Nichi-in Centre for Regenerative Medicine, Mylapore and gave an invited lecture on “Mebiol Gel, A thermo reversible polymer as a scaffold for three dimensional culture of Huh7 cell line with improved hepatocyte differentiation marker expression and HCV replication”. Dr Nivedita Chatterjee attended the Conference on “Addiction: latest research and the impact of addiction on our lives” at Florey Institute of Neuroscience and Mental Health, Melbourne, Australia on 22nd October, 2015. Dr Nivedita Chatterjee gave an invited lecture on “Modulating innate immunity in the retina; an in vitro model” at University of Melbourne, Department of Optometry and Vision science” on 22nd October, 2015. Dr Dhanashree Ratra participated in the Cataract Kaleidoscope - Golden Jubilee celebrations of Regional Institute of Ophthalmology, from 23rd to 25th October, 2015 at Sitapur and made presentations on “Management of Cataract and diabetic retinopathy” and “Cataract in Vitrectomized eyes- surgical pearls”. Dr J Biswas, Dr Sudha K. Ganesh, Dr S Sudharshan and Dr Parveen Sen attended the Uveitis Society of India meeting at Puducherry from 23rd to 25th October 2015. Dr Biswas gave presentations on “A case presentation of granulomatous anterior uveitis with discussion” and “Retinal vasculitis in Indian scenario”; Dr Sudha K. Ganesh on “Management of Herpetic anterior uveitis: Drug of choice and duration of treatment” and “Special considerations in pediatric uveitis cataracts”; Dr S.Sudharshan on “Uveitis cataract surgery in HIV” and Dr Parveen Sen on “Dislocated IOL in Uveitis surgical management options”. Dr Nivedita Chatterjee gave an invited lecture on “Alleviating HIV Tat induced inflammation: implications for endocannabinoids as therapeutics” at Deakin University, Australia, on 27th October, 2015. Dr J Malathi delivered an invited lecture entitled “Detection of uncultivable and unidentifiable microbes” during National Symposium on Molecular Techniques in Diagnosis & Research at Central Inter- Disciplinary Research Facility (CIDRF), MGMCRI Campus, Puducherry on 31st October 2015. Mr. Purushothaman particpated in the Histotechnology CME Programme at Adyar Cancer Institute on 31st October, 2015. Dr Mohd Shahid Alam and Dr Kirthi Koka attended the Ocular Trauma Society of India Conference, Guwahati on 31st October 2015. Dr Mohd Shahid Alam made a presentation on “Functional & anatomical results of canalicular tear repair with monocanalicular intubation” and Dr Kirthi Koka on “Luck by Chance: Sino–orbital foreign body, an uninvited foreigner”. Dr J. Biswas attended the AIDS Conference at Mumbai from 29th October to 1st November, 2015. Dr Bipasha Mukherjee, Dr Nirmala Subramanian, and Dr Swakshyar Saumya Pal participated in the Ocular Trauma Society of India Meet at Guwahati, from 31st October to 1st November 2015. Dr Bipasha Mukherjee made a presentation on “Evaluation of Post operative Visual Loss” and “Chemical & Thermal injuries of the orbit & adnexa”, Dr Nirmala Subramanian on “Various aspects of lid and adenexa repair post molten metal injury” and Dr Pal on “Size does matter - a challenging case of an intraocular glass foreign body”.

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Dr Prema Padmanabhan participated in the Cornea Connect by Aravind Hospital, Coimbatore from 31st October to 1st November 2015 and made presentations on “Contact Lenses – do they still play a role?”, “Can corneal endothelium re-grow?” and “Have my indications changed?” The first meeting on “Formulation of PCV Guidelines for India” was conducted at Kochi from 7th to 8th November 2015 and it was attended by Dr Muna P Bhende. Dr Muna P Bhende participated in the Annual Meeting of Ophthalmic Society of West Bengal, Kolkata, from 14th to 15th November 2015 and made presentations on “Current Management of PCV” and “Panelist: Challenging cases- Medical Retina”. Dr Angayarkanni attended the 42nd National Conference of the Association of Clinical Biochemists of India at PGIMER, Chandigarh, from 25th to 28th November 2015 and delivered an invited talk on “Serum PONase activity in relation to Lipid profile and PON1 gene variants in Age Related Macular Degeneration”. Dr K Lily Therese and Mr. N Murugan attended 39th Microcon – 2015 - National Conference of the Indian Association of Medical Microbiologists at Department of Microbiology JIPMER, Puducherry from 27th to 29th November 2015. Mr. Murugan presented a poster entitled “Development and application of Set of Multiplex PCRs for rapid diagnosis of drug resistant genes among clinical isolates of Pseudomonas aeruginosa”. Dr S R Bharathi Devi presented a poster titled on “Paraoxonase 2 Down regulates ER stress and inhibits the CML induced inflammatory response in macrovascular endothelial cell” in the 14th FAOBMB congress and 84th Annual meeting of SBC(I) at Centre for Cellular and Molecular Biology at Hyderabad from 27th to 30th Nov 2015. Dr Geetha Iyer, Dr Sudhir R R and Dr Meena Lakshmipathy participated in the Keracon 2015 – 3rd National Meeting of Cornea Society of India at Kolkata, from 11th to 13th December2015. Dr Geetha Iyer gave presentations on “Ocular chemical injuries – A stepwise approach to visual recovery” and “Spurious eye drops/Chemical injuries – case study”; Dr Sudhir on “Panelist: Biostatistics Basics” and Dr Meena Lakshmipathy on “Role of AC tap”. Dr T S Surendran attended the Strabismus & Pediatric Ophthalmological Society of India Conference at Coimbatore on 12th December 2015 and chaired the “Basics of Strabismus” session. Dr Angayarkanni participated in the Center for Bio-separation Technology Meet at Vellore Institute of Technology, Vellore, on 8th January 2016 and gave a guest lecture on “Serum Paraoxonase activity in relation to lipid profile and PON1 gene variants in age-related macular degeneration”. The Department of Neuro-ophthalmology of Sankara Nethralaya organized an international conference, SYNAPSE 2k16 - Symposium in Neuro Ophthalmology : Afferents Plus Efferents on 9th & 10th January 2016. The conference was attended by nearly 300 delegates. Dr Geetha Iyer attended the 1st International Stevens Johnson Syndrome Symposium at Japan, from January 23rd to 24th 2016 and gave a guest lecture on “Ocular Sequelae of SJS - Our understanding over 25 years”. Dr Vinata Muralidharan, Dr Parveen Sen, Dr Shantha B, Dr Bipasha Mukherjee, Dr Ambika S, Dr Amala Elizabeth George, and Dr Rama Rajagopal participated in the World Ophthalmology Congress at Mexico, from February 5th to 9th, 2016. Dr Vinata Muralidharan made a poster presentation on “Outcome of vitreous surgery for complications of proliferative diabetic retinopathy in type I diabetes in subjects aged 30 years”; Dr Parveen Sen on “Outcomes of pediatric scleral fixated posterior chamber intraocular lens implantation in a tertiary eye care centre in India” and Dr Shantha on “Prevalence, incidence and risk factors for the development of elevated intraocular pressure following penetrating keratoplasty”. Dr Bipasha Mukherjee made poster presentations on “Wegener's granulomatosis with solitary eyelid

63 MEDICAL RESEARCH FOUNDATION involvement manifesting as acquired ptosis” & “Rare but beware- malignancies of the lacrimal sac”; Dr Ambika on “Clinical features and treatment outcome of Pediatric Ocular Myasthenia Gravis (POMG) in an ophthalmic institution”; Dr Amala Elizabeth George on “Viral anterior Uveitis”; Dr Rama Rajagopal on “Combined corneal and posterior segment infections – etiology, role of Landers keratoprosthesis and outcome” and “Surgical excision in conjunctival squamous cell carcinoma (SCC) - clinical profile, risk factors and surgical outcome”. Ms. M Vimalin Jeyalatha attended the training programme entitled “Optimisation techniques for Western blot & Immunohistochemistry” conducted at the Indian Institute of Technology, Chennai on 25th February 2016. Dr Biswas J, Dr T S Surendran, Dr Ekta Rishi, Dr Sudha K Ganesh, Dr Meenakshi S, Dr Jaydeep Avinash Walinjkar, Dr Jaya Prakash, Dr Veena Baskaran, Dr Bipasha Mukherjee, Dr R R Sudhir, Dr Suchitra Pradeep, Dr Rajiv Raman, Dr B Shantha, Dr Amala E George, Dr Srikanth R, and Dr Sumita Agarkar attended the 74th Annual Conference of All India Ophthalmological Society at Kolkata from 24th to 28th February 2016. Dr Biswas made presentations on “Update in tubercular uveitis”, “Balancing academics and clinics”, “Inflammatory venous occlusions”, “Leadership in ophthalmology in private institution” and “Safety and efficacy of mycophenolate mofetil in intermediate uveitis; Dr Surendran on “Synoptophore”, “Orthoptic examination” , “Refraction errors in children”, “Diplopia charting” and “IC: Pearls in refractive errors in children”; Dr Ekta Rishi on “Role of PCR in Mycobacterium tuberculosis endophthalmitis; Dr Sudha Ganesh on “Updates on infections uveitis viral retinopathy” and Dr Meenakshi on “Evaluation of squint”. Dr Jaydeep Avinash Walinjkar made poster presentations on “Short-term changes in choroidal thickness after bevacizumab for neovascular AMD measured by SS-OCT”, “CNVM complicating the management of circumscribed choroidal haemangioma (CCH) – A rare phenomenon”, “Analysis of choroidal thickness in eyes with DME treated with focal laser using SS-OCT” & “Chorioretinal atrophy after successful macular hole surgery in a case of atypical RP”; Dr Jaya Prakash made poster presentations on “Outcome of pars plana vitrecotmy for complicated uvieitis in children and young adults” & “Clinical profile and outcomes of uveitis in young patients undergoing para plana vitrectomy” and Dr Veena Baskaran on “Atypical CSR”. Dr Bipasha Mukherjee gave a poster presentation on “Lacrimal sac sarcoidosis mimicking dacryocystitis” and a paper presentation on “Epidemiological study on benign lesions of the eyelids”; Dr Sudhir made paper presentations on “Pterygium surgery and amniotic membrane transplant”, “ Biostatistics in Ophthalmology”, “How to set up a paperless hospital” & “Need for EMR in ophthalmology”; Dr Suchitra Pradeep made a paper presentation on “Update on treatment of infectious uveitis”; Dr Rajiv Raman on “Comparison of FFA and OCT findings in various stages of parafoveal telangiectasia”, “Acute endophthalmitis following intravitreal Anti VEGF and triamcinolone acetonide injections”, “Qualitative and quantitative study of choroid in Vogt Koyanagi Harada's disease by Swept source OCT” and “Eylea in AMD”. Dr B Shantha made poster presentations on “Prevalence, incidence and risk factors for the development of elevated intraocular pressure following penetrating keratoplasty”, “IC: Surgical management of glaucoma in uveitic eyes”, “IC: Surgical management of uveitis” & “IC: A multidisciplinary approach”; Dr Amala George made a paper presentation on “Viral anterior uveitis”; Dr Srikanth made poster presentations on “Teacher's in ophthalmology programme” & “Practice pattern of NLD obstruction messaging technique among practitioners”; Dr Sumita Agarkar made paper presentations on “IC: controversies in pediatric cataracts” & “Intraocular lens in uveitis cataract within the consensus” and Dr Vikas Khetan made a presentation on “Enucleation after chemotherapy”. Dr B Shantha attended the Sri Lanka Ophthalmology Society Meeting at Colombo, from 12th to 13th March 2016 and made presentations on “Anterior segment imaging in glaucoma” and ”Diagnostic dilemmas in POAG”.

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The SN ONGC Department of Genetics and Molecular Biology organized the 41st Indian Society of Human Genetics Annual Meeting & International Conference (ISHG 2016), at Sri Mutha Venkata Subba Rao Concert Hall, Harrington Road, Chennai, from 3rd to 5th March 2016. The conference was attended by nearly 400 delegates. Prof. Bainsbridge, Vitreo-retinal Surgeon from UK, Dr Myles Axton, Chief Editor, Nature Genetics Journal, USA, Dr Sowmya Swaminathan, Director General, Indian Council of Medical Research and other distinguished scientists from many National and International institutes participated in the conference. Dr J Narayanan attended National workshop on “Protein Engineering and Design” held at IISER, Mohali between 15th and 19th March 2016. Dr Biswas J, Dr Sudha K Ganesh, and Dr Bhaskar Srinivasan participated in the 31st Congress of the Asia- Pacific Academy of Ophthalmology (APAO), Taipei, from 24th to 27th March 2016. Dr Biswas J gave presentations on “Tubercular uveitis”, “Tubercular vasculitis”, and “Biopsy pathology of uveitis”; Dr Sudha Ganesh on “Management of cataract in Uveitis eye” and Dr Bhaskar Srinivasan on “Devastating Ocular Surface Diseases”.

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DISTINGUISHED VISITORS His Excellency, Dr. K. Rosaiah, Governor of Tamil Nadu visited our Foundation on 7th April 2015 to inaugurate Lions Diabetic Retinopathy Skills Transfer Training Programme. Lion Robert “Bob”E.corlew, Second Vice President, Lions Clubs International visited our foundation on April 07, 2015. Dr. P. Prasannaraj, Additional Secretary from Medical Council of India, New Delhi, visited the research laboratories on 16th April 2015. Dr. Arvind from Massachusetts Institute of Technology (MIT), Boston, USA visited the Genetics Lab on 17th April, 2015. Dr. Vieal Shah, Unipath Laboratory from Ahmadabad visited the L & T Microbiology Research Centre on 23rd April 2015. Dr. Narendra Nayar, A J Institute of Medical Science visited the L & T Microbiology Research Centre on 25th April 2015. Mr. Kyungsoo Kim, Consul General of the Republic of Korea visited our foundation on 20th May 2015. Mr. Harjinder Singh Lallie, Senior Teaching Fellow (Cyber Security), Course leader for Msc Cyber Security & Management, University of Warwick, UK, visited our foundation on 4th June 2015 and gave a talk on “Cyber Security – Threats, challenges in Healthcare and Medical devices”. Dr. Arup Das, Chief Ophthalmology Regents Professor, University of New Mexico School of Medicine, USA visited our foundation on 12th June 2015 and gave a talk on “ Diabetic Retinopathy”. Dr. Sharath Patil and Mr. Jagadesh Sastri from Lions Club team from Nasik visited the Genetics Lab on 15th June 2015 Mr. Gaoussou M, Minister of Transport, Cote d`lvoire, Mr Sainy Tiemele, Tiemele, Ambassador of Cote d`Ivoire at India, visited our foundation on 1st July 2015 Dr. S. V. Eswaran, Emeritus Scientist, Council of Scientific and Industrial Research, visited the research laboratories on 4th July 2015. Dr Daniel B Rootman, Doheny Eye Center UCLA – Pasadena, California visited our foundation on 14th July 2015 and gave a talk on “Assessment of thyroid eye disease & Orbital vascular disease” Dr. G.V.S.Murthy, Dr. Raghupathy and his team from Indian Institute of Public Health at Bangalore visited the research laboratories on 15th July 2015. Dr. Bibhaskar, Consultant & Head, Department of Genetics, Madras Medical Mission, Chennai visited the Genetics Lab on 15th July 2015 Ms Khadija Hatim Yusufali Instructor for blind & visually impaired, Canada visited our foundation on 20th July 2015 and gave a talk on “White reflex in a child” Dr. Jagat Kanwar from Deakin University, Australia visited the Ocular Pathology Lab on 5th August 2015. Mr. Craig Mcfarlane, Director of Educational and Professional Services, Essilor Amera, visited our foundation on 7th August, 2015. Mr. Jagdish Mithu Chanrai, Founder – Mission for Vision visited our foundation on 10th August 2015.

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Dr Rowan Candy, Associate Professor, Indiana University School of Optometry, USA visited our foundation on 19th August 2015 and gave a talk on “How do babies see”. Dr. James Armitage, Head and Dr. Richa Verma, Lecturer, Vision Sciences, from Deakin University, Australia visited our research laboratories on 12th August 2015. Ms. Judith Fox, sister of Terry Fox visited our foundation on 22nd August 2015. Mr. Stanley Gomes, Senior Trade Commissioner from Indo – Canadian High Commission from Canada, with his wife, visited the Pathology laboratory on 25th August, 2015 Dr. Akhilesh Pandey, Professor, Johns Hopkins University School of Medicine, USA and Dr Harsha Gowda, Scientist, Institute of Bioinformatics, Bangalore visited the research Laboratories 8th September 2015 Dr. UN Das and Mrs. UN Das visited the Biochemistry Lab on 29th September 2015. Dr. Jacob VV, Scientist, Department of Science and Technology (DST), from New Delhi visited the Biochemistry Lab on 12th October 2015. Dr. R K Shukla, Department of Zoology, St Xavier's College, Ranchi, Jharkhand, visited the Biochemistry Lab on 24th October 2015. Prof Narasing A Rao, Ophthalmic Pathology Laboratory & Uveitis Service, USC Eye Institute, USA visited our foundation and gave a talk on “Retinal Vasculitis” on 27th October 2015. Dr Gaurav K. Shah, M.D., Prof. of Clinical Ophthalmology & Visual Sciences, Director of Vitreo retinal Fellowship Program, Washington University School of Medicine, visited our foundation on 7th January 2016 and gave a lecture on “Retinal Detachment and Challenges & Update on Ocular Imaging” Prof. Luis Afonso, Director in International Research Training, Deakin University, Australia, visited our research laboratories and interacted with Scientists on 18th February 2016. Dr. Myles Axton Chief Editor, Nature Genetics, from New York visited our foundation on 2nd March 2016. Prof. James Bainbridge Professor of Retinal Studies, from UCL Institute of Ophthalmology, UK visited our foundation on 5th March 2016. Dr. Aksai Anand, Editor, Annals of Neurosciences from PGIMER, Chandigarh visited the L & T Microbiology Research Centre on 5th March 2016. Mr. A K Gayan, Ministry of Health and Quality of Lfe of the Rebulic of Mauritius visited our foundation on 15th March 2016. Dr. Neetu Mundra from Sir H.N.Reliance Foundation Hospital from Mumbai visited our foundation.

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