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Name and Designation NAME Dr. Chanderdeep Tandon Dean – Faculty of Biosciences & Biotechnology DESIGNATION Professor & Director – Amity Institute of Biotechnology, AUUP, Noida EMAIL ID [email protected] CONTACT NUMBER 0120-4392721 RESEARCH INTERESTS Proteomics, Medical Biotechnology, Management of Urolithiasis EDUCATIONAL QUALIFICATIONS: Name of College / University Degree Year Panjab University, Chandigarh B.Sc. (Hons.) (Biochemistry) 1989 Panjab University, Chandigarh M.Sc. (Hons.) (Biochemistry) 1990 Panjab University, Chandigarh Ph.D. 1998 EXPERIENCE (in chronological order): Total 20 Years Research & Teaching Designation Type of post held Name of the Institute Year (From – To) (teaching/ research) *Dean – Faculty of Biosciences & Biotechnology, Professor & Teaching, Research Amity Institute of Biotechnology, *Oct. 2018 – Till date Director & Administrative AUUP, Noida Oct. 2014 onwards Teaching & Jaypee University of Information Professor Research Technology, Waknaghat, Solan (H.P.) July 2010 – Sep 2014 Associate Teaching & Jaypee University of Information Professor Research Technology, Waknaghat, Solan (H.P.) July 2007 – July 2010 Assistant Teaching & Jaypee University of Information Professor Research Technology, Waknaghat, Solan (H.P.) July 2004 – July 2007 Teaching & Jaypee University of Information Senior Lecturer Research Technology, Waknaghat, Solan (H.P.) June 2003 – July 2004 Biology, University of Kansas Post-Doctoral Medical Center (KUMC), Kansas Fellow Research City, Kansas, USA 2000 - 2002 Faculty Deptt. of Biochemistry, Panjab (Adjunct) Teaching University , Chandigarh 1999 – 2000 Research Research Deptt. of Biochemistry, Panjab Associate University , Chandigarh 1998 – 1999 Awarded: 11 No. of Ph.D. students supervised Ongoing: 4 No. of Post-Doc One DST Inspire Faculty is working under my mentorship No. of M.Tech. Students supervised: 22 No. of B.Tech. Students supervised: 33 1. Singh A, Tandon S, Tandon C. An update on vascular calcification and potential therapeutics.Mol Biol Rep. 2021 Jan 4. doi: 10.1007/s11033-020-06086-y. Online ahead of print (Impact factor~ 2.19) https://rdcu.be/cc32I 2. Kumar D, Baligar P, Srivastav R, Narad P, Raj S, Tandon C, Tandon S. Stem Cell Based Preclinical Drug Development and Toxicity Prediction. Curr Pharm Des. 2020 Oct 18. doi: 10.2174/1381612826666201019104712. Epub ahead of print. PMID: 33076801. (Impact factor~ 2.2) 3. Shifa Narula, Simran Tandon, Dhruv Kumar, Swati Varshney, Khushboo Adlakha, Shantanu Sengupta, Shrawan Kumar Singh, Chanderdeep Tandon. Human Kidney Stone Matrix Proteins Alleviate Hyperoxaluria Induced Renal Stress by Targeting Cell-Crystal Interactions" Life Sciences 2020 Vol. 262, 1 December 2020, https://doi.org/10.1016/j.lfs.2020.118498 (Impact factor~ 3.65) 4. Sabiha Khan, Debadatta Nayak, Anil Khurana, Raj PUBLICATIONS Kumar Manchanda, Chanderdeep Tandon, Simran (75) Tandon In vitro assessment of homeopathic potencies of Hydrastis Canadensis on hormone dependent and independent breast cancer. Homeopathy 2020 Nov;109(4):198-206. doi: 10.1055/s-0040- 1709668. Epub 2020 Jul (Impact factor~1.52) 5. Kaushik, J., Tandon, S., Bhardwaj, R, Kaur T, Singla S. K., Kumar J, Tandon C Delving into the Antiurolithiatic Potential of Tribulus terrestris Extract Through –In Vivo Efficacy and Preclinical Safety Investigations in Wistar Rats. Scientific Reports (natureresearch) 9, 15969 (2019) doi:10.1038/s41598- 019-52398-w (Impact factor~4.01) 6. Rajpal Srivastav , Rakesh Sharma , Simran Tandon, Chanderdeep Tandon. Role of DHH Superfamily Proteins in Nucleic Acids Metabolism and Stress Tolerance in Prokaryotes and Eukaryotes. Int J Biol Macromol. 2019 Apr 15; 127:66-75. doi: 10.1016/j.ijbiomac.2018.12.123. (Impact factor~5.16) 7. Mittal, A.,Tandon, S.,Singla, S.K.,Tandon, C. Modulation of lithiatic injury to renal epithelial cells by aqueous extract of Terminalia arjuna. Journal of Herbal Medicine (2018) 63– 70 https://doi.org/10.1016/j.hermed.2018.01.003:13 (Impact factor~1.6) 8. Narula S, Tandon C, Tandon S (2018). Role of matrix metalloproteinases in degenerative kidney disorders. Curr Med Chem, 25, 1-12. (I.F.- 3.21) 9. Narula S, Tandon S, Baligar P, Singh SK, Tandon C (2017). Human kidney stone matrix: Latent potential to restrain COM induced cytotoxicity and inflammatory response. Chem Biol Interact. 278: 114-122. (I.F~3.26) 10. Kaushik J, Tandon S, Gupta V, Nayyar J, Singla SK, Tandon C (2017). Response surface methodology based extraction of Tribulus terrestris leads to an upsurge of antilithiatic potential by inhibition of calcium oxalate crystallization processes. PLoS One. 2017 Aug 28; 12(8):e0183218.doi:10.1371/journal.pone.01832 18. (Impact factor~2.8) 11. Bhardwaj R, Tandon C, Dhawan DK, Kaur T (2017). Effect of endoplasmic reticulum stress inhibition on hyperoxaluria-induced oxidative stress: influence on cellular ROS sources. World J. Urol. 2017 Aug 24. doi: 10.1007/s00345-017-2083-8. (Impact factor~2.14) 12. Bhardwaj R, Bhardwaj A, Tandon C, Dhawan DK, Bijarnia RK, Kaur T (2017). Implication of hyperoxaluria on osteopontin and ER stress mediated apoptosis in renal tissue of rats. Exp Mol Pathol. 102(3):384-390 (I.F. 2.638) 13. Mittal A, Tandon S, Singla SK, Tandon C (2017). Cytoprotective and anti-apoptotic role of Terminalia arjuna on oxalate injured renal epithelial cells. Cytotechnology, doi: 10.1007/s10616-017-0065-8. (I.F. 1.9) PUBLICATIONS 14. Kumar V, Chauhan RS and Tandon C (2017). Biosynthesis (75) and therapeutic implications of Iridoid glycosides from Picrorhiza genus: the road ahead. J. Plant Biochem. Biotechnol. Volume 26 [Indexed in PubMed ‘MEDLINE’, SCOPUS etc] 15. Mittal A, Tandon S, Singla SK, Tandon C (2016). Mechanistic Insights into the Antilithiatic Proteins from Terminalia arjuna: A Proteomic Approach in Urolithiasis. Plos One, 11 (9): e0162600. (I.F. 2.8) 16. Narula S, Tandon S, Singh SK, Tandon C (2016). Kidney stone matrix proteins ameliorate calcium oxalate monohydrate induced apoptotic injury to renal epithelial cells. Life Sciences, 164(2016): 23-30. (I.F. 2.95) 17. Sharma M, Sud A, Kaur T, Tandon C, Singla SK (2016). N- acetyl cysteine with Apocynin prevents hyperoxaluria induced mitochondrial protein perturbations in nephrolithiasis. Free Radical Research, 50(9): 1032-44. (I.F. 2.9) 18. Kumar V, Shitiz K, Chauhan RS, Sood H, Tandon C (2016). Tracking dynamics of enzyme activities and their gene expression in Picrorhiza kurroa with respect to picroside accumulation. Journal of Plant Biochemistry and Biotechnology, 25(2):125-132 (I.F. 1.35) 19. Kumar V, Chauhan RS and Tandon C (2016). Biosynthesis and therapeutic implications of Iridoid glycosides from Picrorhiza genus: the road ahead. Journal of Plant Biochemistry and Biotechnology, 26(1): 1-13. (I.F. 1.35) 20. Mittal A, Tandon S, Singla SK and Tandon C (2016). In vitro inhibition of calcium oxalate crystallization and crystal adherence to renal tubular epithelial cells by Terminalia arjuna. Urolithiasis, 44(2): 117-25. (I.F. 1.5) 21. Mittal A, Tandon S, Singla SK, Tandon C (2015). In vitro studies reveal antiurolithic effect of Terminalia arjuna using quantitative morphological information from computerized microscopy. International Brazilian Journal of Urology, 41(5): 935-44. (I.F. 0.95). 22. Kumar V, Sharma N, Shitiz K, Singh TR, Tandon C, Sood H, Chauhan RS (2015). An insight into conflux of metabolic traffic leading to picroside-I biosynthesis by tracking molecular time course changes in a medicinal herb, Picrorhiza kurroa. Plant Cell, Tissue and Organ Culture, 123(2): 435- 441. (I.F. 2.3). 23. Kumar V, Kumar V, Chauhan RS, Sood H and TandonC(2014) Cost effective quantification of picrosides in Picrorhizakurroa by employing response surface methodology using HPLC-UV. J Plant BiochemBiotechnol. DOI 10.1007/s/13562-014-0285-3. (Impact Factor 1.094) 24. Sud A, Chauhan RS and TandonC(2014) Mass Spectrometric Analysis of Differentially Expressed Proteins in an Endangered Medicinal Herb, Picrorhizakurroa. Biomed Res Int. 2014: 326405. (Impact Factor 2.706) 25. Arora S, Tandon C and Tandon S (2014)Evaluation of the cytotoxic effects of CAM therapies: An in vitro study in normal kidney cell lines. The Sci.World J. 2014: 452892. (Impact Factor 1.219) 26. Aggarwal A, Singla SK and TandonC (2014). Urolithiasis: Phytotherapy as an adjunct therapy. Indian J Exp Biol. 52: PUBLICATIONS 103-111. (Impact Factor 0.753) (75) 27. Aggarwal KP, Narula S, Kakkar M and TandonC (2013). Nephrolithiasis: Molecular Mechanism of Renal Stone Formation and the Critical Role Played by Modulators. Biomed Res Int. 2013: 292953. (Impact Factor 2.706) 28. Aggarwal KP, Tandon S, Naik PK, Singh SK and Tandon C(2013) Peeping into Human Renal Calcium Oxalate Stone Matrix: Characterization of Novel Proteins Involved in the Intricate Mechanism of Urolithiasis. PLoSONE. 8(7): e69916.(Impact Factor 3.534) 29. Sud A, Chauhan RS and TandonC(2013) Identification of imperative enzymes by differential protein expression in Picrorhizakurroa under metabolite accumulating and non- accumulating conditions. Protein PeptLett. 20(7): 826-835. (Impact Factor 1.735) 30. Aggarwal KP, Tandon S, Singh SK and TandonC(2013)2D map of proteins from human renal stone matrix and evaluation of their effect on oxalate induced renal tubular epithelial cell injury.IntBraz J Urol. 39(1):128-36. (Impact Factor 0.956) 31. Aggarwal KP, Tandon S, Naik PK, Singh SK and TandonC(2013) Novel Antilithiatic Cationic Proteins from Human Calcium Oxalate Renal Stone Matrix identified by MALDI-TOF-MS endowed with cytoprotective potential: An Insight into Molecular Mechanism of Urolithiasis. ClinChimActa. 415: 181-190. (Impact Factor 2.764) 32. Aggarwal A, Tandon S, Singla SK andTandonC(2012) A novel antilithiatic protein from Tribulusterrestrishavingcytoprotectivepotency.Prot einPeptLett. 19(8): 812-819.(Impact Factor 1.735) 33. Tayal S, Bandopadhy P, Aggarwal A, Tandon S and TandonC(2012)Cytoprotective role of the aqueous extract of Terminaliachebula on renal epithelial cells. IntBraz J Urol. 38(2): 204-214. (Impact Factor 0.956) 34. Aggarwal A, Singla SK, Gandhi M and TandonC(2012)Preventive and curative effects of Achyranthesaspera Linn. extract in experimentally induced nephrolithiasis. Indian J Exp Biol. 50: 201-208. (Impact Factor 0.753) 35.
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