Implementation of CYP2D6 Copy-Number Imputation Panel and Frequency of Key
medRxiv preprint doi: https://doi.org/10.1101/2020.11.13.20227058; this version posted November 16, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission. Implementation of CYP2D6 copy-number imputation panel and frequency of key pharmacogenetic variants in Finnish individuals with a psychotic disorder K. Häkkinen1,2*, JI. Kiiski3,4, M. Lähteenvuo1,2*, T. Jukuri2*,5, K. Suokas2*,6, J. Niemi-Pynttäri2*,7, T. Kieseppä2*,8,9, T. Männynsalo2*,7, A. Wegelius2*,8,9, W. Haaki2*,10, K. Lahdensuo2*,11, R. Kajanne2, MA. Kaunisto2, A. Tuulio-Henriksson12, O. Kampman6,13, J. Hietala10, J. Veijola5,14, J. Lönnqvist9,15, E. Isometsä8, T. Paunio8,9,15, J. Suvisaari9, E. Kalso16, M. Niemi3,4,17, J. Tiihonen1,18,19, M. Daly2,20,21, A. Palotie2,20,21, AV. Ahola-Olli2,20,21 1Department of Forensic Psychiatry, Niuvanniemi Hospital, University of Eastern Finland, FI- 70240 Kuopio, Finland 2Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, FI-00014 Helsinki, Finland, *years 2016-2018 3Department of Clinical Pharmacology, University of Helsinki, FI-00014 Helsinki, Finland 4Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, FI-00014 Helsinki, Finland 5Department of Psychiatry, University of Oulu, FI-90014 Oulu, Finland 6Tampere University, FI-33014 Tampere, Finland 7Social Services and Health Care Sector, City
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