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Ringworm Refers to Infections Caused by Several Fungi, Commonly Called

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Ringworm Refers to Infections Caused by Several Fungi, Commonly Called Ringworm Sarah McSweeney-Ryan, MD Megan Sandel, MD ingworm refers to infections caused by several fungi, commonly called tinea, that can grow on skin, hair, or nails. The descriptive name “ringworm” Rcomes from the characteristic rash that grows outward in the shape of a ring, with worm-like borders and normal skin in the middle. Each of these fungal infections is named for the most commonly reported skin disorder. Acne is the part of the body infected. The most common sites most common. Approximately one out of every five are: people will eventually develop a tinea infection. • tinea capitis, on the scalp; The site of tinea fungal infections varies widely • tinea corporis, on the body, excluding the among different age groups: groin, feet, hands, beard region, and scalp; • fungal infections of the scalp and skin • tinea pedis (“athlete’s foot”) and manus, on (tinea capitis or tinea corporis) are com- the feet and hands; mon in young children, while infections of • tinea unguium, under the nails; the feet and toes are not. Approximately Tinea Corporis. • tinea cruris (“jock itch”), on the groin area. 3-8% of children in the USA are infected This young boy has Infection of the scalp is especially troublesome, with tinea capitis. Some people are “car- an itchy ring-like rash as it may cause permanent hair loss when untreated. riers” of tinea capitis but are themselves involving the face and Ringworm infection of the nails can be difficult ear. The borders are not symptomatic. These “carriers” often clearly marked, to eradicate and can cause severe damage to the unknowingly infect and reinfect other the central area is fingernails and toenails. people in their homes and therefore pose a clear, and there is Tinea pedis is very common among homeless challenge to treatment; prominent scaling persons living in shelters and on the streets. A • fungal infection under the nails (tinea of the skin. Photo courtesy separate chapter has been devoted to this particular unguium) is more common in adult and of the CDC form of ringworm. For more information please see elderly populations; the Tinea Pedis chapter. • “athlete’s foot” (tinea pedis) is common in adolescents and adults and spreads easily Prevalence and Distribution within families and institutions; In the USA fungal infections are the second The Health Care of Homeless Persons - Part I - Ringworm 107 • sharing clothes and contact with infected (top) pets, including dogs, cats, and guinea Tinea Corporis. pigs, are additional ways that fungi can be This gentleman at McInnis House spread to the skin. complained of this Some types of fungal infections can spread from itchy rash of the one part of the body to another. Most people who chest. Note the have tinea cruris also have tinea pedis. Fungal infec- raised, clearly marked borders, along with tion of the toes can spread to the toenails, resulting the central area of in tinea unguium. clearing. Persons with ringworm are infectious for as long Photo by as the cultures of the lesions show the presence of James O’Connell MD fungi or as long as the skin lesions persist. (bottom) Tinea Corporis. Diagnosis This fungal infection Clinical involved the skin The term ringworm describes the appearance of of the upper arm and back, and the ring-shaped lesions with raised (worm-like) edges. appearance of these Ringworm typically refers to tinea corporis, the skin ring-like lesions with lesions. The raised borders are red, often with clear sharp borders and or normal appearing skin in the center of the “ring”. central clearing is The rash is often mildly itchy. again very typical of this infection. Scalp infection (tinea capitis) can be inflam- Photo by matory or non-inflammatory. Sore, boggy pustules Howard Koh MD and hair loss characterize inflammatory infections. • fungal infection of the groin (tinea cruris), Inflammation of the hair follicles causes the hair to commonly called “jock itch”, typically oc- break off and the scalp to become scaled and red. curs in young adult men, especially those The infection may spread locally, creating a larger who wear athletic equipment. circle of lost hair, or may be diffuse over the entire The prevalence of fungal infections has racial scalp. Non-inflammatory tinea capitis produces variations as well. Fungal infection on the scalp and little scaling, redness, or pustules. The hair shaft can head (tinea capitis) is more common in African- break at the scalp causing a “black dot” appearance. American children than in Caucasian children. Fungal infection of the hands and feet (tinea Fungal infections are more common in people manus and pedis) frequently involves the webbed with weak immune systems. Since fungal infections area between the fingers and the toes, where the skin can promote the growth of other bacteria on the may become red, cracked, and eroded. Dryness skin, clinicians should closely monitor the progress and fine white scaling on the palms of the hands of fungal infections in those who are immunocom- or bottom of the feet can also be evidence of fungal promised. infection. Due to the breakdown of the skin barrier, secondary bacterial infections of the feet may occur. Transmission This often leads to pain and swelling of the feet. Ringworm infection occurs most often through Nails infected with fungus (tinea unguium) will direct contact with an infected person, animal, or generally thicken, become brittle, ridged, and finally surface. Broken or irritated skin promotes transmis- split. Caseation produced by the infection causes a sion, as does warmth and humidity for some fungi. tan to brown discoloration of the nail plate. The Damp places such as bathroom floors, shower stalls, infection may make the nail very difficult to cut. and rugs often provide ideal opportunities for trans- “Jock itch” (tinea cruris) is characterized by the mission of the fungi that cause ringworm: scaling of skin and itchy, red irritation of the groin • walking barefoot on an infected surface and inner thighs that extends symmetrically to the can result in fungal infection of the feet front of the thighs. The rash usually spares the and toes; penis and scrotum. The appearance of the rash can • combs, hats, and barber’s instruments can be confused with candida (yeast) infections, which spread ringworm to the scalp and skin; typically have small “satellite” lesions outside the border of the rash. 108 The Health Care of Homeless Persons - Part I - Ringworm The Health Care of Homeless Persons - Part I - Ringworm 109 Tinea Versicolor. This chronic, asymptomatic fungal infection of the skin is marked by areas of hypopigmentation which become especially prominent during exposure to sunlight. Photo by Howard Koh MD cream, such as clotrimazole (LotriminTM 1% cream Laboratory or lotion), terbinafine (LamisilTM ), ketoconazole To confirm the diagnosis, a piece of hair, nail, (NizoralTM), or one of many others. These lotions or skin from an active border of the rash may or creams should be applied once or twice a day to be scraped or clipped off and examined under a the entire rash and at least 2 centimeters beyond the microscope. The specimen should first be dissolved borders of the rash for a minimum of four weeks. in potassium hydroxide preparation (KOH). Since Treatment should generally be continued for one microscopic exams are often negative, a culture week after resolution of rash. using a special medium (Sabouraud’s agar) may be Systemic antifungal therapy for tinea capitis or necessary. Fungi grow slowly so these results may other skin infection resistant to topical treatment is take weeks. typically with griseofulvin, once a day for 4-8 weeks Examination of the scalp with a Wood’s light or until 2 weeks after resolution of symptoms. to demonstrate fungal infection is of limited use. In adults, tinea capitis may be treated with oral Some fungi will appear bright green under such a terbinafine as a first line medication. There is some light. However, the fungus which most commonly evidence that oral terbinafine is a better first line causes tinea capitis in the USA does not fluoresce medication for children as well, though current under this light. recommendations are for the use of griseofulvin. Griseofulvin may cause headaches and gastro- Treatment intestinal disturbances and should always be taken Fungal infections are treated by two primary with fatty foods. Griseofulvin can also temporarily routes: topical or systemic medications. Topical interfere with normal liver enzymes, necessitating antifungal medication is appropriate initial treat- frequent tests to monitor liver function, especially ment for skin infections (tinea corporis, pedis, when treating refractory cases for prolonged periods manus, and cruris), unless the infection involves or using doses of 20 mg/kg or higher. an extensive area. Oral or systemic treatment with Nail infections (tinea unguium) are very diffi- antifungal medications is required for all infec- cult to treat and are frequently resistant to treatment tions involving the scalp or nails (tinea capitis and with oral griseofulvin. Improved cure rates have been unguium) and for fungal skin infections that do not seen with the use of oral terbinafine and itraconazole respond to topical treatment. for the treatment of fungal nail infection. Treat- Topical treatment is typically with an antifungal ment with terbinafine is for a minimum of 6 weeks, 108 The Health Care of Homeless Persons - Part I - Ringworm The Health Care of Homeless Persons - Part I - Ringworm 109 and treatment with itraconazole (SporanoxTM) is for Summary a minimum of 3 months. These medications may “Ringworm” refers to several diseases caused have side effects on the gastrointestinal system, espe- by fungi that can invade the skin, scalp, and nails. cially the liver. In resistant fungal nail infections, Depending on the location of the infection, mild to removal of the nail bed may be necessary.
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