CURRICULUM VITAE Kay Redfield Jamison, Ph.D. Correspondence To
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Treatment, Adherence, and Disability in Bipolar Disorder
Petri Arvilommi Treatment, Adherence, and Disability in Bipolar Disorder ACADEMIC DISSERTATION To be presented with the permission of the Faculty of Medicine, University of Helsinki, for public examination at the HUCH Psychiatry Centre, Christian Sibelius Auditorium, Välskärinkatu 12, on 10th June 2016, at 12 noon. Department of Psychiatry University of Helsinki Helsinki, Finland Helsinki 2016 Supervisors Professor Erkki Isometsä, M.D., Ph.D. Department of Psychiatry, Faculty of Medicine University of Helsinki Helsinki, Finland and Docent Kirsi Suominen, M.D., Ph.D. Department of Mental Health and Substance Abuse, City of Helsinki, Social Services and Health Care Helsinki, Finland Reviewers Professor Jyrki Korkeila, M.D., Ph.D. Faculty of Medicine, University of Turku, Turku, Finland and Associate professor Olli Kampman, M.D., Ph.D. School of Medicine, University of Tampere Seinäjoki Hospital District, Department of Psychiatry Tampere, Finland Opponent Professor Esa Leinonen, M.D., Ph.D. School of Medicine, University of Tampere Dissertationes Scholae Doctoralis Ad Sanitatem Investigandam Universitatis Helsinkiensis ISBN 978-951-51-2205-6 (pbk.) ISBN 978-951-51-2206-3 (PDF) ISSN 2342-3161 (print) ISSN 2342-317X (online) http://ethesis.helsinki.fi T a m p e r e , F i n l a n d “The endless questioning finally ended. My psychiatrist looked at me, there was no uncertainty in his voice. “Manic-depressive illness.” I admired his bluntness. I wished him locusts on his lands and a pox upon his house. Silent, unbelievable rage. I smiled pleasantly. He smiled back. The war had just begun.” Kay Redfield Jamison “An Unquiet Mind” (1995) Abstract Petri Arvilommi. -
Bipolar Disorder
Bipolar Disorder D E P A R T M E N T O F H E A L T H A N D H U M A N S E R V I C E S P U B L I C H E A L T H S E R V I C E N A T I O N A L I N S T I T U T E S O F H E A L T H National Institute of Mental Health ipolar disorder, also known as manic- depressive illness, is a brain disorder that causes unusual shifts in a person�s mood, energy, and ability to function. Different from the normal ups and downs that everyone goes through, the symptoms of bipolar disorder are severe. They can result in damaged relationships, poor job or school performance, and even suicide. But there is good news: bipolar disorder can be treated, and people with this illness can lead full and productive lives. More than 2 million American adults,1 or about 1 percent of the population age 18 and older in any given year,2 have bipolar disorder. Bipolar disorder typically develops in late adolescence or early adulthood. However, some people have their first symptoms during childhood, and some develop them late in life. It is often not recognized as an illness, and people may suffer for years before it is properly diagnosed and treated. Like diabetes or heart disease, bipolar disorder is a long-term illness that must be carefully managed throughout a person�s life. -
Obituary Johan Schioldann
Obituary Johan Schioldann To cite this version: Johan Schioldann. Obituary. History of Psychiatry, SAGE Publications, 2006, 17 (2), pp.247-252. 10.1177/0957154X06061602. hal-00570850 HAL Id: hal-00570850 https://hal.archives-ouvertes.fr/hal-00570850 Submitted on 1 Mar 2011 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. HPY 17(2) Schou obituary 2/5/06 09:21 Page 1 History of Psychiatry, 17(2): 247–252 Copyright © 2006 SAGE Publications (London, Thousand Oaks, CA and New Delhi) www.sagepublications.com [200606] DOI: 10.1177/0957154X06061602 Obituary Mogens Abelin Schou (1918–2005) – half a century with lithium JOHAN SCHIOLDANN* Mogens Schou, the most prominent of the pioneers of modern lithium therapy, passed away on 29 September 2005. He was 86 years old. A couple of days before, he had returned home from an IGSLI (International Group for the Study of Lithium-Treated Patients) meeting in Poland. He succumbed to pneumonia, having managed to finish a last manuscript just hours before. Schou was born in Copenhagen in 1918. His father, Hans Jacob Schou, an influential figure in Danish psychiatry, adopted the notion of a biological basis of affective disorders from his countryman, Carl Lange, one of the early era lithium pioneers (Schioldann, 2001), and established a research laboratory to study the possible biochemical and physiological changes in manic-depressive illness (Schou, 2005). -
‗DEFINED NOT by TIME, but by MOOD': FIRST-PERSON NARRATIVES of BIPOLAR DISORDER by CHRISTINE ANDREA MUERI Submitted in Parti
‗DEFINED NOT BY TIME, BUT BY MOOD‘: FIRST-PERSON NARRATIVES OF BIPOLAR DISORDER by CHRISTINE ANDREA MUERI Submitted in partial fulfillment of the requirements For the degree of Doctor of Philosophy Dissertation Adviser: Dr. Kimberly Emmons Department of English CASE WESTERN RESERVE UNIVERSITY August 2011 2 CASE WESTERN RESERVE UNIVERSITY SCHOOL OF GRADUATE STUDIES We hereby approve the thesis/dissertation of Christine Andrea Mueri candidate for the Doctor of Philosophy degree *. (signed) Kimberly K. Emmons (chair of the committee) Kurt Koenigsberger Todd Oakley Jonathan Sadowsky May 20, 2011 *We also certify that written approval has been obtained for any proprietary material contained therein. 3 I dedicate this dissertation to Isabelle, Genevieve, and Little Man for their encouragement, unconditional love, and constant companionship, without which none of this would have been achieved. To Angie, Levi, and my parents: some small piece of this belongs to you as well. 4 Table of Contents Dedication 3 List of tables 5 List of figures 6 Acknowledgements 7 Abstract 8 Chapter 1: Introduction 9 Chapter 2: The Bipolar Story 28 Chapter 3: The Lay of the Bipolar Land 64 Chapter 4: Containing the Chaos 103 Chapter 5: Incorporating Order 136 Chapter 6: Conclusion 173 Appendix 1 191 Works Cited 194 5 List of Tables 1. Diagnostic Criteria for Manic and Depressive Episodes 28 2. Therapeutic Approaches for Treating Bipolar Disorder 30 3. List of chapters from table of contents 134 6 List of Figures 1. Bipolar narratives published by year, 2000-2010 20 2. Graph from Gene Leboy, Bipolar Expeditions 132 7 Acknowledgements I gratefully acknowledge my advisor, Kimberly Emmons, for her ongoing guidance and infinite patience. -
Kay Redfield Jamison
The Rhoda and Bernard Sarnat International Prize in Mental Health 2015 Honoree Kay Redfield Jamison, PhD Dalio Family Professor in Mood Disorders and Professor of Psychiatry, Johns Hopkins University School of Medicine Co-Director, Johns Hopkins Mood Disorders Center The 2015 Rhoda and Bernard Sarnat International Prize in Mental Health is awarded to Kay Jamison for her profound insights into affective disorders and suicide that have not only advanced the field, but also transformed public understanding. Her work combines cutting-edge research with deeply humanistic and often personal narratives—an approach that has cut through stigma to become a cornerstone of the field and a beacon for sufferers of mood disorders. Dr. Jamison is the co-author of Manic-Depressive Illness, the standard medical textbook in the field, and has written more than 125 scientific and clinical articles about mood disorders, suicide, creativity, and lithium. However, her greatest impact may lie in her works of narrative nonfiction, which probe links between creativity and mental illness, trace the natural history of affective disorders, and explore the suicidal mind. An Unquiet Mind: A Memoir of Moods and Madness, which chronicles Dr. Jamison’s own experience with manic-depressive illness, marked a major milestone in combating stigma in the psychiatric profession. It remained on the New York Times best-seller list for 5 months and has been translated into 25 languages. Johns Hopkins Hospital, where Dr. Jamison co-directs the Mood Disorders Center, praises the book on its website as a kind of “bibliotherapy” that does “what pills can’t: It lets patients read for themselves how destructive not taking their medicine can be, it tells of the healing power of structure, psychotherapy and a social network. -
A Nation of Maniacs: Understanding Commodified Mania Through Bipolar Narratives Alexandra Marino
orienting / 1 A Nation of Maniacs: Understanding Commodified Mania Through Bipolar Narratives Alexandra Marino Excerpt “How could one, should one, recapture that intensity…the glorious moods of dancing all night and into the morning, the gliding through starfields and dancing along the rings of Saturn, the zany manic enthusiasms? How can one ever bring back the long summer days of passion, the remembrance of lilacs, ecstasy, and gin fizzes that spilled down over a garden wall, and the peals of riotous laughter that lasted until the sun came up or the police arrived?” — Jamison, 211 This quote epitomizes the conflicted feelings Dr. Kay Redfield Jamison has towards her exhilarating and transcendental manic episodes. In her autobiography An Unquiet Mind: A Memoir of Moods and Madness, Jamison chronicles her battle with the cyclical highs and lows of bipolar disorder, a disease that for her is simultaneously lethal and life-affirming. Her manic highs are characterized by hypersexuality, fluidity of ideas, exuberance, extreme confidence, and hyperactivity (128). In contrast, when she cycles into depression after a manic episode, a desolate fog encapsulates her mind, bringing thoughts of suicide (39). Even as a professor of psychiatry who understands firsthand the ramifications of depression, she battles against taking the very same medications she urges her own patients to take. She fears that these mood stabilizers would eradicate the sweeping majesty of her mania, as depicted above (92). After years of resisting consistent treatment, she finally decides to stay on her medication, realizing that a life with less dramatic fluctuations in moods is preferable over no life at all. -
The International College of Neuropsychopharmacology (CINP
King’s Research Portal DOI: 10.1093/ijnp/pyw091 Document Version Publisher's PDF, also known as Version of record Link to publication record in King's Research Portal Citation for published version (APA): Fountoulakis, K. N., Young, A., Yatham, L., Grunze, H., Vieta, E., Blier, P., ... Kasper, S. (2016). The International College of Neuropsychopharmacology (CINP) Treatment Guidelines for Bipolar Disorder in Adults (CINP-BD-2017), Part 1: Background and Methods of the Development of Guidelines. International Journal of Neuropsychopharmacology . DOI: 10.1093/ijnp/pyw091 Citing this paper Please note that where the full-text provided on King's Research Portal is the Author Accepted Manuscript or Post-Print version this may differ from the final Published version. If citing, it is advised that you check and use the publisher's definitive version for pagination, volume/issue, and date of publication details. And where the final published version is provided on the Research Portal, if citing you are again advised to check the publisher's website for any subsequent corrections. General rights Copyright and moral rights for the publications made accessible in the Research Portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognize and abide by the legal requirements associated with these rights. •Users may download and print one copy of any publication from the Research Portal for the purpose of private study or research. •You may not further distribute the material or use it for any profit-making activity or commercial gain •You may freely distribute the URL identifying the publication in the Research Portal Take down policy If you believe that this document breaches copyright please contact [email protected] providing details, and we will remove access to the work immediately and investigate your claim. -
Mood Stabilizers in Psychiatric Disorders and Mechanisms Learnt from in Vitro Model Systems
International Journal of Molecular Sciences Review Mood Stabilizers in Psychiatric Disorders and Mechanisms Learnt from In Vitro Model Systems Ritu Nayak, Idan Rosh, Irina Kustanovich and Shani Stern * Sagol Department of Neurobiology, University of Haifa, Haifa 3498838, Israel; [email protected] (R.N.); [email protected] (I.R.); [email protected] (I.K.) * Correspondence: [email protected] Abstract: Bipolar disorder (BD) and schizophrenia are psychiatric disorders that manifest unusual mental, behavioral, and emotional patterns leading to suffering and disability. These disorders span heterogeneous conditions with variable heredity and elusive pathophysiology. Mood stabilizers such as lithium and valproic acid (VPA) have been shown to be effective in BD and, to some extent in schizophrenia. This review highlights the efficacy of lithium and VPA treatment in several randomized, controlled human trials conducted in patients suffering from BD and schizophrenia. Furthermore, we also address the importance of using induced pluripotent stem cells (iPSCs) as a disease model for mirroring the disease’s phenotypes. In BD, iPSC-derived neurons enabled finding an endophenotype of hyperexcitability with increased hyperpolarizations. Some of the disease phenotypes were significantly alleviated by lithium treatment. VPA studies have also reported rescuing the Wnt/β-catenin pathway and reducing activity. Another significant contribution of iPSC models can be attributed to studying the molecular etiologies of schizophrenia such as abnormal differentiation of patient-derived neural stem cells, decreased neuronal connectivity and neurite Citation: Nayak, R.; Rosh, I.; number, impaired synaptic function, and altered gene expression patterns. Overall, despite significant Kustanovich, I.; Stern, S. Mood advances using these novel models, much more work remains to fully understand the mechanisms Stabilizers in Psychiatric Disorders by which these disorders affect the patients’ brains. -
Mental Notes
HEALTH / By Jane Marion Pictured: sity School of Medi- derstanding Suicide, Exuberance, and a Doctors in the cine—is their struggle 1,262-page tome that is considered the House: Kay with bipolar illness definitive textbook on bipolar disorder). Redfield Jamison at home with (also known as manic- Associate professor of psychiatry at Thomas Traill. depression), a mood Yale School of Medicine Thomas Sty- disorder characterized ron, whose father, the late literary titan by episodes of severe depression and mania. William Styron, was a close friend of Although this enigmatic illness (suffered Jamison’s, has high praise for her. by more than 10 million people in the United “She is an absolute giant in the field of States alone, according to the National Al- psychiatry as someone who has been able liance on Mental Illness) was first classified to combine top-notch academic work dating back to the time of Hippocrates, it with this incredible personal story, which has lately found its way into the mainstream, has been such a huge service to people thanks to the success of the feature film Sil- who suffer from mental illness,” he says. ver Linings Playbook and Showtime’s wildly Her students are starry-eyed, too. popular Homeland, whose producer once “When medical residents come to look contacted Jamison to advise on an episode. at Hopkins, they say, ‘If I’m here, do I Of course, to Jamison, the disease is actually get to work with Dr. Jamison?’” nothing new: She is one of the most widely says Dr. Karen Swartz, associate profes- regarded experts on mood disorders in the sor of psychiatry and behavioral sciences world and has spent the greater part of her at Hopkins. -
Los Angeles Bibliography
A HISTORICAL BIBLIOGRAPHY OF THE BUILT ENVIRONMENT IN THE LOS ANGELES METROPOLITAN AREA Compiled by Richard Longstreth 1998, revised 16 May 2018 This listing focuses on historical studies, with an emphasis is on scholarly work published during the past thirty years. I have also included a section on popular pictorial histories due to the wealth of information they afford. To keep the scope manageable, the geographic area covered is primarily limited to Los Angeles and Orange counties, except in cases where a community, such as Santa Barbara; a building, such as the Mission Inn; or an architect, such as Irving Gill, are of transcendent importance to the region. Thanks go to Kenneth Breisch, Dora Crouch, Thomas Hines, Greg Hise, Gail Ostergren, and Martin Schiesl for adding to the list. Additions, corrections, and updates are welcome. Please send them to me at [email protected]. G E N E R A L H I S T O R I E S A N D U R B A N I S M Abu-Lughod, Janet, New York, Chicago, Los Angeles: America's Global Cities, Minneapolis: University of Minnesota Press, 1999 Adler, Sy, "The Transformation of the Pacific Electric Railway: Bradford Snell, Roger Rabbit, and the Politics of Transportation in Los Angeles," Urban Affairs Quarterly 27 (September 1991): 51-86 Akimoto, Fukuo, “Charles H. Cheney of California,” Planning Perspectives 18 (July 2003): 253-75 Allen, James P., and Eugene Turner, The Ethnic Quilt: Population Diversity in Southern California Northridge: Center for Geographical Studies, California State University, Northridge, 1997 Avila, Eric, “The Folklore of the Freeway: Space, Culture, and Identity in Postwar Los Angeles,” Aztlan 23 (spring 1998): 15-31 _________, Popular Culture in the Age of White Flight: Fear and Fantasy in Suburban Los Angeles, Berkeley: University of California Pres, 2004 Axelrod, Jeremiah B. -
Melancholia and Mania: the Historical Contributions of Aretaeus of Cappadocia and Emil Kraepelin
University of Calgary PRISM: University of Calgary's Digital Repository Graduate Studies The Vault: Electronic Theses and Dissertations 2020-04-27 Melancholia and Mania: The Historical Contributions of Aretaeus of Cappadocia and Emil Kraepelin Marlier, Krystal Marlier, K. (2020). Melancholia and Mania: The Historical Contributions of Aretaeus of Cappadocia and Emil Kraepelin ( Unpublished master's thesis). University of Calgary, Calgary, AB. http://hdl.handle.net/1880/111923 master thesis University of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission. Downloaded from PRISM: https://prism.ucalgary.ca UNIVERSITY OF CALGARY Melancholia and Mania: The Historical Contributions of Aretaeus of Cappadocia and Emil Kraepelin by Krystal Marlier A THESIS SUBMITTED TO THE FACULTY OF GRADUATE STUDIES IN PARTIAL FULFILMENT OF THE REQUIREMENTS FOR THE DEGREE OF MASTER OF ARTS GRADUATE PROGRAM IN GREEK AND ROMAN STUDIES CALGARY, ALBERTA APRIL, 2020 © Krystal Marlier 2020 Abstract Two millennia ago, Aretaeus of Cappadocia, a physician from the first to second century CE, first presented a modern portrayal of the relationship between μανίη (mania) and μελαγχολίη (melancholia). His understanding is reflective of the nineteenth-century German clinician, Emil Kraepelin. I propose that Kraepelin and Aretaeus possess more similarities than differences. They were homologous in research techniques and nosology, with one significant difference in aetiology. Presently, Aretaeus’ classification remains recognized in psychiatry, though with a slight deviation in understanding and under different psychiatric labels. -
Mogens Schou
Aalborg Universitet Mogens Schou (1918-2005) a scientist, a doctor and a lithium champion Rybakowski, Janusz K; Vinberg, Maj; Kessing, Lars V; Malhi, Gin S; Selo, Marylou; Licht, Rasmus W Published in: Bipolar Disorders DOI (link to publication from Publisher): 10.1111/bdi.12739 Publication date: 2018 Document Version Accepted author manuscript, peer reviewed version Link to publication from Aalborg University Citation for published version (APA): Rybakowski, J. K., Vinberg, M., Kessing, L. V., Malhi, G. S., Selo, M., & Licht, R. W. (2018). Mogens Schou (1918-2005): a scientist, a doctor and a lithium champion. Bipolar Disorders, 20(8), 680-682. https://doi.org/10.1111/bdi.12739 General rights Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights. ? Users may download and print one copy of any publication from the public portal for the purpose of private study or research. ? You may not further distribute the material or use it for any profit-making activity or commercial gain ? You may freely distribute the URL identifying the publication in the public portal ? Take down policy If you believe that this document breaches copyright please contact us at [email protected] providing details, and we will remove access to the work immediately and investigate your claim. Downloaded from vbn.aau.dk on: September 23, 2021 DR. JANUSZ RYBAKOWSKI (Orcid ID : 0000-0003-0577-0381) Article type : Editorial Mogens Schou (1918-2005): a scientist, a doctor and a lithium champion.