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Advances in Heart Disease Prevention and Rehabilitation

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Advances in Heart Disease Prevention and Rehabilitation 8th Annual Advances in Heart Disease Prevention and Rehabilitation Helping Patients Help Themselves Saturday, March 5, 2016 Detroit Marriott Troy • Troy, Michigan INTRODUCTION Recent studies have shown that arterial inflammation plays a key role in the development and progression of atherosclerosis, that acute myocardial infarctions often evolve from mild-to-moderate coronary artery stenoses, that patients who experience a fatal coronary event invariably had antecedent exposure to one or more major coronary risk factors (i.e., hypercholesterolemia, hypertension, cigarette smoking, diabetes, obesity), that angiographic findings may vastly underestimate underlying atherosclerotic coronary artery disease, and that aggressive medical management may represent a safe and effective alternative to many elective coronary revascularization procedures. Moreover, cardiorespiratory fitness appears to be one of the strongest prognostic markers in persons with and without heart disease. Collectively, these data highlight the value of lifestyle modification and contemporary pharmacotherapies in the prevention of initial and recurrent cardiovascular events. Several mechanisms may contribute to improved clinical outcomes, including partial (albeit small) anatomic regression of coronary artery stenoses, a reduced incidence of coronary inflammation, platelet aggregation, and plaque rupture, and enhanced coronary artery vasomotor function. Conference registrants will be provided the latest information on heart disease prevention and rehabilitation by a nationally distinguished faculty to “help patients help themselves.” Target audience This one-day conference will provide cardiologists, internists, physician assistants, cardiac nursing personnel, and associated allied health professionals (e.g., physiologists, physical and occupational therapists, cardiac rehabilitation personnel, dietitians, recreational directors, public health professionals, health care administrators) with an overview of recent advances in the primary and secondary prevention of cardiovascular disease. CME accreditation and credit designation William Beaumont Hospital is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. William Beaumont Hospital designates this live activity for a maximum of 6.0 AMA PRA Category 1 Credit(s)TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Non-physician professionals should check with their individual credentialing bodies to confirm that participation in this CME activity will be approved for credit. CME credits can be used to meet the continuing education requirements needed for Michigan physician assistant and nursing relicensure without limitation. Disclosure All planning committee members and speakers have been asked to disclose any significant relationships they may have with commercial companies within the past 12 months that are relevant to their presentation. The presence or absence of relationships as well as off-label discussion of products will be disclosed at the time of the conference. Acknowledgement This conference will be partially supported by educational grants and display fees from commercial supporters. OBJECTIVES By attending this conference, attendees should improve their ability to: • Clarify the role of psychosocial factors in health • Summarize the most recent, and ongoing, and disease, with specific reference to bona fide epidemiologic studies on the appropriate mind-body interventions beyond cardioprotective “dose” of physical activity for health and heart medications and coronary revascularization disease prevention. procedures. • Delineate the causes of physical inactivity that are • Identify the potential impact of lifestyle modification associated with contemporary technologic advances and drug therapy on cardiovascular risk reduction, and our increasingly hypokinetic lifestyles, and with specific reference to hypercholesterolemia, suggest strategies/interventions to combat the hypertension, cigarette smoking, physical inactivity, associated consequences. diabetes and obesity. • Review an interesting case study pertaining to a • Explain the role of aspirin in the primary prevention patient with cardiovascular disease, including the of major adverse cardiac events, including the diagnostic evaluations employed, the treatment patient subsets most likely to benefit from this approach, and related outcomes. prophylactic therapy. • Understand the importance of defining, predicting, • Describe the key components of a cardioprotective promoting and favorably impacting cardiovascular diet, including the restriction of saturated fat health, rather than simply preventing initial and and cholesterol, avoidance of trans fats and recurrent cardiovascular events. salt restriction. • Describe the proven benefits of research-based • Summarize recent guidelines regarding the medical therapy on coronary artery disease, and our management of cholesterol and lipoprotein failure to consistently deliver it. metabolism, especially LDL and HDL cholesterol, • Highlight recent advances and innovations in as these subfractions relate directly and inversely to cardiovascular medicine including hypothermic atherosclerosis and vascular diseases, respectively. treatment strategies for hospitalized patients who • Identify high risk and cardioprotective levels of have experienced sudden cardiac death. physical activity and cardiorespiratory fitness • Clarify the risks and benefits of non-culprit (metabolic equivalents, METs) for patients with revascularization in patients with acute and without cardiovascular disease, with specific coronary syndrome. reference to health outcomes associated with varied doses of exercise (i.e., moderate, vigorous, extreme). • Review the profound negative impact of cigarette smoking on cardiovascular and all-cause mortality, • Discuss novel pharmacologic treatments (e.g., with specific reference to the deleterious effects of PCSK9 Inhibitors) and their mechanisms of action for secondhand smoke and the benefits of communities patients with elevated LDL cholesterol, despite statin adopting a smoke-free environment to rapidly improve therapy or in patients who are statin intolerant. the cardiovascular health of its citizens. • Examine the interpretation and implications of • Identify new interventions and technologic advances several recent epidemiologic studies linking to prevent acute cardiovascular events, include stroke increased mortality or heart disease rates in and transient ischemic attacks. population subsets participating in high or extreme levels of physical activity. • Review the evidence that obesity as a cardiovascular disease risk factor cannot be accurately assessed with the commonly used body mass index. Rather, it is the inner visceral/ectopic fat that appears to negatively impact health outcomes. FACULTY Director Beaumont faculty Barry A. Franklin, Ph.D. Steven Almany, M.D. Director, Preventive Cardiology and Rehabilitation Director, Catheterization Laboratory Beaumont Hospital – Royal Oak Associate Professor, Department Professor, Department of Internal Medicine of Internal Medicine Oakland University William Beaumont School of Medicine OUWB School of Medicine Guest faculty Abhay Neil Bilolikar, M.D. Clinical Cardiologist Eric R. Bates, M.D. Assistant Professor, Department Professor of Internal Medicine of Internal Medicine University of Michigan OUWB School of Medicine Ann Arbor, Michigan Kavitha Chinnaiyan, M.D. Director, Cardiovascular Imaging Education Associate Professor, Department of Internal Medicine Jean-Pierre Després, Ph.D. OUWB School of Medicine Professor, Department of Kinesiology Faculty of Medicine, Université Laval Simon R. Dixon, MBChB Director of Research, Cardiology Chair, Department of Cardiovascular Medicine Québec Heart and Lung Institute Professor, Department of Internal Medicine Quebec, Canada OUWB School of Medicine Harold Z. Friedman, M.D. Raymond Gibbons, M.D. Medical Director, Preventive Cardiology Arthur M. and Gladys D. Gray and Rehabilitation Professor of Medicine Associate Professor, Department Mayo Clinic of Internal Medicine Rochester, Minnesota OUWB School of Medicine Abdul R. Halabi, M.D. Interventional Cardiologist I-Min Lee, M.D., ScD Assistant Professor, Department Professor of Medicine, Harvard of Internal Medicine Medical School OUWB School of Medicine Professor of Epidemiology, Harvard T.H. Steven B.H. Timmis, M.D. Chan School of Public Health Director, Coronary Care Unit Brigham and Women’s Hospital Assistant Professor, Department Boston, Massachusetts of Internal Medicine William C. Roberts, M.D. OUWB School of Medicine Executive Director, Baylor Heart and Justin E. Trivax, M.D. Vascular Institute Interventional Cardiologist Dean, A. Webb Roberts Center for Assistant Professor, Department Continuing Medical Education of Baylor of Internal Medicine Health Care System, Baylor Scott & White OUWB School of Medicine Editor in Chief, The American Journal of Cardiology and Baylor University Medical Center Proceedings Dallas, Texas SCHEDULE OF EVENTS 7:15-7:50 a.m. Registration and Continental Breakfast 7:50-8 a.m. Welcome and Opening Remarks Barry A. Franklin, Ph.D. 8-8:35 a.m. Physical Activity and Health: How Little is Too Little, and How Much is Too Much? I-Min Lee, M.D., ScD 8:35-9:10 a.m. Recent Advances in Cardiovascular Medicine Simon Dixon, MBChB 9:10-9:45 a.m. Visceral Obesity and Cardiovascular
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