RESUME Dr K. A. Aravinda Kumar M.Sc., Ph.D
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RESUME Dr K. A. Aravinda kumar M.Sc., Ph.D. E-mail: [email protected] D.O.B: 20/08/1982 Present address: 3-54, Sri Balaji Nilayam, Chilakapalem, Etcherla post, Srikakulam District, Andhra Pradesh, India, PIN: 532402 Mobile No: 9797676763, 8074532506. Objective Ph.D. graduate with research background in synthetic organic and medicinal chemistry, Teaching experience in CHEMISTRY under graduate and M.Sc levels and have good chemistry knowledge. Teaching & Research Experience: 9/07/18 to till date Associate Professor of the department of Humanities and Basic sciences Pragati Engineering College (Atonomus). ADB road, Surampalem, Near Peddapuram, E.G. Dt., A.P. 24/10/2017 to : Associate Professor of the department of Humanities and Basic sciences, Sri 31/05/18 Venkateswara College of Engineering and Technology,Etcherla, Srikakulam district. (Ratified Faculty as Assistant Professor by JNTUK). 2006 – 2007 Lecturer, G. B. R Degree college, Anaparthi, E.G.District, A.P 2007 - 2009 : Senior Chemist, GVK BIO Sciences, Uppal, Hyderabad, Telangana, India 2009 - 2011 : Junior Research Fellow, Medicinal Chemistry Division, Indian Institute of Integrative Medicine, Council of Scientific and Industrial Research (CSIR), Canal road, Jammu-180001, INDIA 2011- 2014 : Senior Research Fellow, Medicinal Chemistry Division, Indian Institute of Integrative Medicine, Council of Scientific and Industrial Research (CSIR), Canal road, Jammu-180001, INDIA 2014- 2016 : Senior Project Fellow, Medicinal Chemistry Division, Indian Institute of Integrative Medicine, Council of Scientific and Industrial Research (CSIR), Canal road, Jammu-180001, INDIA Education: 2009 - 2017 : Ph.D. in organic Chemistry, Thesis work done at Medicinal Chemistry Division, CSIR-IIIM, Canal road, Jammu, India. Registered with Acharya Nagarjuna University. Supervisor: Dr. Ram A Vishwakarma (Director, IIIM-Jammu) Dissertation: 'Liphagal Analogs As Anticancer Agents and Inhibitors of PI3K Signaling Pathway And Development of New Synthetic Methods' 2003 – 2005 : M.Sc (Organic Chemistry), Department of Chemistry, Andhra University, Vishakapatnam 60.0%. 2000 – 2003 : B.Sc (M.P.C.), Acharya Nagarjuna University. 69.5% List of Publications (International Journals) : 11 1. Aravinda Kumar, K. A.; Venkateswarlu, V.; Vishwakarma, R. A.; Sawant, S. D., A Metal-Free Approach to Carboxylic Acids by Oxidation of Alkyl, Aryl, or Heteroaryl Alkyl Ketones or Arylalkynes. Synthesis., 2015,41, 3161-3168. (Impact factor: 2.689) 2. Aravinda Kumar, K. A.; Venkateswarlu, V.; Gupta, S.; Singh, D.; Vishwakarma, R. A.; Sawant, S. D., DMSO/I2 mediated C-C bond cleavage of [small alpha]-ketoaldehydes followed by C-O bond formation: a metal-free approach for one-pot esterification. Org. Biomol. Chem.., 2015,13, 7973-7978. (Impact factor: 3.564) 3. Venkateswarlu, V.; Pathania, A. S.; Aravinda Kumar, K. A.; Mahajan, P.; Nargotra, A.; Vishwakarma, R. A.; Malik, F. A.; Sawant, S. D., 4-(N-phenyl-N’-substituted benzenesulfonyl)-6-(4- hydroxyphenyl)quinolines as Inhibitors of Mammalian Target of Rapamycin. Bioorg. Med. Chem., 2015, 23, 4237-4247. (Impact factor: 2.793) 4. Jain, S. K.; Aravinda Kumar, K. A.; Bharate, S. B.; Vishwakarma, R. A., Facile access to amides and hydroxamic acids directly from nitroarenes. Org. Biomol. Chem. ,2014, 12, 6465-6469. (Impact factor: 3.564) 5. Venkateswarlu, V.; Aravinda Kumar, K. A.; Balgotra, S.; Reddy, G. L.; Srinivas, M.; Vishwakarma, R. A.; Sawant, S. D., C-H Oxygenation and N-Trifluoroacylation of Arylamines Under Metal-Free Conditions: A Convenient Approach to 2-Aminophenols and N-Trifluoroacyl-ortho-aminophenols. Chem. Eur. J., 2014, 20 (22), 6641-6645. (Impact factor: 5.317) 6. Singh, P. P.; Thatikonda, T.; Aravinda Kumar, K. A.; Sawant, S. D.; Singh, B.; Sharma, A. K.; Sharma, P. R.; Singh, D.; Vishwakarma, R. A., Cu–Mn Spinel Oxide Catalyzed Regioselective Halogenation of Phenols and N-Heteroarenes. J. Org. Chem., 2012, 77 (13), 5823-5828. (Impact factor: 4.849) 7. Sawant, S. D.; Hudwekar, A. D.; Aravinda Kumar, K. A.; Venkateswarlu, V.; Singh, P. P.; Vishwakarma, R. A., Ligand- and base-free synthesis of phenols by rapid oxidation of arylboronic acids using iron(III) oxide. Tetrahedron Lett., 2014, 55 , 811-814. (Impact factor: 2.379) 8. Sawant, S. D.; Srinivas, M.; Aravinda Kumar, K. A.; Lakshma Reddy, G.; Singh, P. P.; Singh, B.; Sharma, A. K.; Sharma, P. R.; Vishwakarma, R. A., Ligand-free C–N bond formation in aqueous medium using a reusable Cu–Mn bimetallic catalyst. Tetrahedron Lett. 2013, 54 (39), 5351-5354. (Impact factor: 2.379) 9. Venkateswarlu, V.; Balgotra, S.; Aravinda Kumar, K. A.; Vishwakarma, R. A.; Sawant, S. D., Metal- Free Chemoselective ortho-C(sp2)–F Bond Hydroxylation and N-Trifluoroacylation of Fluoroarylamines for Domino Synthesis of 2-(N-Trifluoroacyl)aminophenols. Synlett., 2015, 26 (09), 1258-1262. (Impact factor: 2.323) 10. Srinivas, M.; Hudwekar, A. D.; Venkateswarlu, V.; Lakshma Reddy, G.; Aravinda Kumar, K. A.; Vishwakarma, R. A.; Sawant, S. D., A metal-free approach for transamidation of amides with amines in aqueous media. Tetrahedron Lett., 2013, 56 (33), 4775-4779. (Impact factor: 2.379) 11. Venkateswarlu, V.; Kour, J.; Aravinda Kumar, K. A.; Verma, P. K., Reddy, G. L., Hussain, Y.: Sawant, S. D. Direct N-heterocyclization of hydrazines to access styrylated pyrozoles: synthesis of 1,3,5-trisubstituted pyrazoles and dihydropyrazoles. RSC Acv., 2018, 8(47), 26523-26527. (Impact factor: 3.049) Patent: 1. Ram A Vishwakarma, Sanghapal Damodhar Sawant, Kolluru Anjaneya Aravinda Kumar, Mudududdla Ramesh, Qazi Asif Khurshid, Hussain Aashiq, Chanauria Nayan, Boronic acid analogs of liphagal as selective PI3K inhibitors. International publication number WO 2013/140417 A4. Conferences attended / Poster presented 1. Conference attended “Chemical Research Society North Zone Meeting” at University of Jammu, Jammu, India (Nov-2011). 2. Attended and Poster presented at DBT Sponsored National Symposium on Bioinformatics: Challenges in the post-genomic era.(2012) 3. Paper presented in an Internationa Conference “ICRISEM-2018” at Sri Venkateswara College of Engineering and Technology, Etcherla, Srikakulam, Andhra Pradesh. Fellowships and Awards • Best patent award at Indian Institute of Integrative Medicine, Council of Scientific and Industrial Research (CSIR), Canal road, Jammu-180001 in 2013 • Qualified CSIR-UGC-NET-JRF-2007 exam conducted by Council of Scientific and Industrial Research, India in 2007 (in Chemical Sciences). Research expertise/Skills • Reactions performed in laboratory: Grignard, Wittig, BuLi, Suzuki, Heck, Sonagashira, Chan-lam couplings, etc. • Expertise in handling of air and moisture sensitive reactions,Hydrogenation reactions, autoclave reactions • Development of SAR around the target molecule • Purification of compounds through column, Flash, Preparative HPLC/ TLC • Characterization of compounds through 1H, 13C, 2D-NMR spectroscopy and Mass spectrometry • Hand on experience with HPLC (Shimadzu, Labsolutions software) IR (Perkin elmer), Microwave synthesizer (CEM) instruments. • Computer skills such as Ms-Office, chemdraw, scifinder, reaxys and endnote reference manager. .