Product datasheet Anti-CLDN3 Antibody Catalog Number: A04393-1

BOSTER BIOLOGICAL TECHNOLOGY Special NO.1, International Enterprise Center, 2nd Guanshan Road, Wuhan, China

Web: www.boster.com.cn Phone: +86 27 67845390 Fax: +86 27 67845390 Email: [email protected]

Basic Information Product Name Anti-CLDN3 Antibody Name CLDN3 Source Rabbit Species Reactivity Human, Mouse, Rat Tested Application WB Contents Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Immunogen Synthesized peptide derived from the C-terminal region of human -3. at AA rangle: 140-220 Purification Immunogen affinity purified Observed MW 23KD Dilution Ratios Western blot: 1:500-2000

Storage 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing

Background Information Claudin 3, also known as CLDN3, is a which in humans is encoded by the CLDN3 gene. Tight junctions represent one mode of cell-to- in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low- affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.

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FOR RESEARCH USE ONLY. NOT FOR DIAGNOSTIC AND CLINICAL USE. 1 Product datasheet Anti-CLDN3 Antibody Catalog Number: A04393-1

BOSTER BIOLOGICAL TECHNOLOGY Special NO.1, International Enterprise Center, 2nd Guanshan Road, Wuhan, China

Web: www.boster.com.cn Phone: +86 27 67845390 Fax: +86 27 67845390 Email: [email protected]

Selected Validation Data

Western Blot (WB) analysis of specific cells using Claudin-3 Polyclonal antibody.

FOR RESEARCH USE ONLY. NOT FOR DIAGNOSTIC AND CLINICAL USE. 2

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