BOOK REVIEWS 343 The literature references are not grouped but appear at the end of each of the 384 sections. The book abounds with useful summaries and tables. While certain subjects, such as antibody-dependent cell-mediated cytotoxicity, are explained in great detail, others (suppressor T-cells, for example) receive comparatively short shrift. And although much of the material is timely, the section on drug-induced hemolytic anemias is more than ten years out of date. While the Compendium ofImmunology appears to be a useful book for research- ers and students interested in immunology, it would benefit greatly from a thorough editing job.

RAPHAEL ZAHLER Medical Student Yale University School of Medicine

PRINCIPAL DRUGS. AN ALPHABETICAL GUIDE. 6th Ed. By S.J. Hopkins. Salem, New Hampshire, and London, Faber & Faber, 1980. 164 pp. $4.50. Paperbound. The British have the great gift of synopsis. Another example of this skill is this small, pocket-sized dictionary of drugs by S.J. Hopkins. First published in 1958, this sixth edition describes itself as a "fconcise guide to most of the drugs in current use." It is targeted to nurses and other professionals deluged by redundant proprietary and chemical descriptors of new therapeutic agents. The subtitle reveals the organization of its corpus, but in addition a second section provides the proprietary synonyms of 1,100 drug names as well as their "main action." A typical item reads: "Doxepin: An antidepressant of the imipramine type, but with additional tranquillising properties. Used in the treatment of depression accompanied by anxiety. Dose 30 to 300 mg daily." In the United States the Physician's Desk Reference (Medical Economics Co.) has become the premier reference for practical therapeutic information. Its prolix and seemingly redundant detail about drug indications, contraindications, adverse reactions, dose, etc., are contained in some 2,000 pages of microprint. In contrast, Hopkins' dictionary is a clear but exceedingly terse lexicon of drug nomenclature. However, one does not master a language simply by resort to a pocket conversational phrase book. The pithiness of the definitions, while providing conciseness, leaves much to the imagination. Such Spartan clarity unfortunately connotes that most drugs do few things and at fixed doses. Therefore, the question arises: Of what use is this little dictionary? It must have two uses: (1) as a rapid translator of trade names; (2) as an indicator of the principal action of unfamiliar compounds. Any more serious inquiries require a good pharmacology text, or perhaps the "PDR," as a resource. Perhaps this guide might bail out student doctors and nurses drowning in a sea of jargon. One last admonition is that this is a British publication and, as such, trade names and phrasing indigenous to Britain weakens its utility in American hospitals. I could find few genuine errors, except the feeling that a Latin master would not translate pro re nata as "occasionally." Yet as a small portable "crib" on the panoply of modern drugs this book is useful.

DONALD KAY RIKER Department of Pharmacology Yale University School of Medicine