DOCSLIB.ORG

Department of Clinical Physiology, Nuclear Medicine &

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Department of Clinical Physiology, Nuclear Medicine & Department of Clinical Physiology, Nuclear Medicine & PET Annual Report 2019 Rigshospitalet · University of Copenhagen Contents Preface ......................................................................................................................................2 Mission and objectives ...............................................................................................................4 Organisation and staff 2019.......................................................................................................6 Highlights 2019 .......................................................................................................................10 Clinical physiology and nuclear medicine ................................................................................12 PET/CT ..................................................................................................................................14 Artificial intelligence ...............................................................................................................16 Cardiac investigations .............................................................................................................18 Imaging of angiogenesis .........................................................................................................20 Pediatric Nuclear Medicine ......................................................................................................22 Rigshospitalet Children’s Hospital ..................................................................................................................24 King Frederik V founded Rigshospitalet in 1757. Today it has app. 1,250 beds and 12,000 Education ................................................................................................................................26 employees. Research at Rigshospitalet is published in more than 2,000 peer review papers Agfa RIS/PACS ........................................................................................................................28 per year, including >200 higher academic theses (PhD and Doctor of Medical Science). Neuro PET ...............................................................................................................................30 Rigshospitalet is part of The Capital Region of Denmark and is a Copenhagen University MR imaging of muscle function ...............................................................................................32 Hospital. PET/MR ..................................................................................................................................34 Nuclear medicine technologists, radiographers and lab technicians .........................................36 University of Copenhagen Medical secretaries ..................................................................................................................40 The University of Copenhagen was founded in 1479. The Faculty of Health and Medical Cyclotron Section ....................................................................................................................42 Sciences has 10,000 students, including medicine and bioengineering in collaboration with Radiochemistry Section ...........................................................................................................44 The Technical University of Denmark, DTU. The University of Copenhagen is member of Academic and other activities ..................................................................................................48 IARU, the International Alliance of Research Universities and LERU, League of the European Equipment 2019 ......................................................................................................................53 Research Universities. www.ku.dk Studies 2019 ...........................................................................................................................54 Finance ...................................................................................................................................57 Publications .............................................................................................................................58 Podcasts ..................................................................................................................................67 Cluster for Molecular Imaging .................................................................................................68 Research .................................................................................................................................72 Collaboration with The National Hospital of the Faroe Islands .................................................78 Neurobiology Research Unit ....................................................................................................80 Bioengineer in Medicine and Technology ................................................................................82 Preface In 2019 we received a generous donation from the do research as an interdisciplinary effort and all 2019 was a year with many celebrations; Linda M. Thank you very much to Bettina Lundgren for 10 John and Birthe Meyer Foundation of 43,7 mio. groups are involved: Nuclear medicine physicians, Kragh, our Chief Nuclear Medicine Technologist good years as our center director. Bettina Lundgren DKK for a new PET/MRI scanner and research radiologists, physicists, bioengineers, mathema- celebrated her 40 years anniversary as nuclear got a new prestigious job and left the hospital end on artificial intelligence. It was an overwhelming ticians and IT experts, radiochemists, nuclear medicine technologist at Rigshospitalet, and she of August 2019. Vice Director Lene Ørnstrup Chris- gift, and we are honored, grateful and privileged. medicine technologists, radiographers and many was praised by all of us as a unique and wonderful tensen were then both acting director and vice We would like to express our most sincere thank others. leader. She also received the prestigious award director with two jobs for more than half a year. you. It will be implemented in 2020 in new prem- from the hospital: “Årets bioanalytiker 2019”, or Thank you for all your work and the helpful collab- ises in the Finsen building. It will be a major step In 2018 we reported problems with the newly in English: “This year’s technologist 2019”. oration. Thank you to the Department of Radiol- forward for our department and most important implemented Agfa RIS/PACS ICT system for ogy, Head of Department Ilse Vejborg and Chief for our patients and research. We got our first new picture archiving and patient reporting. Unfor- In 2019 Professor Andreas Kjær obtained the pres- Radiographer Johnny Madelung. We appreciate digital PET/CT in Summer 2019, also donated tunately, it has been an uphill struggle also in tigious Lundbeck Foundation Professorship and the positive collaboration very much. by the John and Birthe Meyer Foundation. It is 2019, as the problems continued with defect received a Knighthood for his impressive contribu- a whole new world for both patients and staff. performance, stability and speech; the essentials tions in research and innovation. The department From November 2019 Head of Department, Profes- Thank you very much to the John and Birthe of a well-functioning ICT system in a diagnostic would like to congratulate Andreas Kjær with sor Liselotte Højgaard was also acting head of Meyer Foundation for all the generosity. imaging department. Thank you to everyone for these major achievements. Department of Pathology until March 2020. It has patience and very long hours all year round due to been quite a job to try and help the Department of The department had another busy year with a the dysfunctional system. We would like to express Kate Pedersen Staff Technologist in PET cele- Pathology, who were in a crisis situation. I would higher than ever number of patient investiga- a sincere thank you to all for the stamina, securing brated her 40 years anniversary in Spring 2019, like to express a warm thank you to each and every tions, 196,889 and 176 peer review publications. patient reports in time without any waiting list. and we said thank you for her great efforts for the one at the Department of Pathology for welcoming Research is a key activity and focus area of our department throughout many years. She retired me so warmly and helping remedy the problems. department, and we have a comprehensive CAAI, Clinically Applied Artificial Intelligence, is Fall 2019 and Maria Pejtersen is the new Staff research program directed towards innovative our new research group with young people devel- Technologist in PET. A warm welcome. Maria Our aim is to deliver the best patient treatment and solutions to solve unmet clinical needs in our oping artificial intelligence for better imaging Pejtersen has initiated a close collaboration with the best research and education. Thank you to all patients. We adjust our research program to be with improved image quality and lower radiation our section in Glostrup and KF to assure the best staff members, collaborators and international clinically relevant and timely, and we have special dose – already now applied in our routine clinical use of our competences and scanners. colleagues for making this possible. focus on implementation of personalized or studies. This is very important for patients and for precision medicine in collaboration with Rigshos-
Load more

Recommended publications
  • Long-Term Follow-Up of Thyroid Incidentalomas Visualized with 18F
    diagnostics Article Long-Term Follow-Up of Thyroid Incidentalomas Visualized with 18F-Fluorodeoxyglucose Positron Emission Tomography—Impact of Thyroid Scintigraphy in the Diagnostic Work-Up Kirsten Korsholm 1,*, Michala Reichkendler 1, Louise Alslev 1, Åse Krogh Rasmussen 2 and Peter Oturai 1 1 Department of Clinical Physiology, Nuclear Medicine and PET, Copenhagen University Hospital, Rigshospitalet, DK-2100 Copenhagen, Denmark; [email protected] (M.R.); [email protected] (L.A.); [email protected] (P.O.) 2 Department of Endocrinology, Copenhagen University Hospital, Rigshospitalet, DK-2100 Copenhagen, Denmark; [email protected] * Correspondence: [email protected] Abstract: Our objective was to evaluate the frequency of malignancy in incidental thyroidal uptake on 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in a cohort of Danish patients, and furthermore to evaluate the impact of thyroid scinti-graphy in the diagnostic work-up. All whole-body PET/CT reports from 1 January 2010 to 31 December 2013 Citation: Korsholm, K.; were retrospectively reviewed and further analyzed if visually increased thyroidal FDG uptake was Reichkendler, M.; Alslev, L.; reported. Patient electronic files were searched for further thyroid evaluation. Of 13,195 18F-FDG- Rasmussen, Å.K.; Oturai, P. PET/CT scans in 9114 patients, 312 PET/CT reports mentioned incidental thyroid FDG-uptake, and Long-Term Follow-Up of Thyroid 279 patients were included in the study (3.1%). The thyroid was further investigated in 137 patients Incidentalomas Visualized with 18F-Fluorodeoxyglucose Positron (49%), and 75 patients underwent thyroid scintigraphy. A total of 57 patients had a thyroid biopsy Emission Tomography—Impact of and 21 proceeded to surgery.
    [Show full text]
  • Reference Values for Lung Function Tests in Men: Regression Equations with Smoking Variables
    Upsala J Med Sci 91: 299-310, 1986 Reference Values for Lung Function Tests in Men: Regression Equations with Smoking Variables Hans Hedenstrom, Per Malmberg and Hrafn V. Fridriksson The Department of Clinical Physiology, University Hospital, Uppsala, Sweden, The Research Department, National Board of Occupational Safety and Health, Solna, Sweden, and the Ministry of Health and Social Security, Reykjavik, Iceland ABSTRACT Prediction formulas for static and dynamic spirometry, gas distribution, static lung mechanics and the transfer test were derived from measurements in healthy men. The measurements included total lung capacity, residual volume, airways resistance, static elastic recoil pressure of the lung, static compliance, closing volume, slope of the alveolar plateau (phase 1111, flow-volume variables (including mean transit time) during breathing of air or a helium/oxygen mixture, and conventional spirometric indices. The results from 146 smokers and 124 never-smokers were evaluated separately and combined. For all lung function tests a single regression equation was obtained. The prediction formulas included time-re1 ated smoking variables and were Val id for both smokers and never-smokers. For many lung function tests, a nonlinear age coefficient resulted in a significant reduction in variance compared with.. simple linear models. Heavy tobacco smoking influenced most lung function tests less than ageing from 20 to 70 years, but for airways resistance, transfer factor and phase 111 the opposite was found. INTRODUCTION In research on occupational factors, which may influence pulmonary function, many different lung function tests may be employed in research of early signs of functional impairment. Confounding factors such as age, body size and tobacco smoking must be controlled.
    [Show full text]
  • Standardised Lung Function Testing
    Thorax: first published as 10.1136/thx.39.12.881 on 1 December 1984. Downloaded from Thorax 1984;39:881-886 Editorial Standardised lung function testing Quality control is an essential ingredient of all clini- Bulletin (Clinical Respiratory Physiology).2 The cal laboratory work and it has been difficult to authors, who are all notable experts in this field, achieve in clinical respiratory physiology. Tests of have tackled all of the problems of standardisation respiratory function call for the active cooperation and produced a series of recommendations which of an untrained individual who has to perform quite are required reading for everyone who is concerned complex manoeuvres on request. To reach the posi- with the organisation of a clinical respiratory tion where different laboratories would produce the laboratory. The recommendations are concerned same result on the same patient, a number of condi- firstly with the performance of the tests and secondly tions have to be met. First, the respiratory man- with the provision of reference values. oeuvres requested must be identical. Secondly, the As the lack of accepted standards has been a apparatus must respond in the same way to the same major problem for epidemiologists concerned with stimulus. Thirdly, the results have to be calculated in lung disease, the National Heart and Lung Institute a standard way and expressed in conventional units. (NHLI) in the United States also embarked on an Finally, the reference or normal values have to be epidemiology standardisation project, eventually agreed between the laboratories, if estimates of the published in full in 1978.3 This document was con- likelihood of normality are to be provided.
    [Show full text]
  • Strategic Review of Cardiac Physiology Services in England: Final Report
    STRATEGIC REVIEW OF CARDIAC PHYSIOLOGY SERVICES IN ENGLAND: FINAL REPORT Strategic Review of Cardiac Physiology Services in England Page 1 Final Report: 12/05/2015 CONTENTS Page Foreword 3 Summary of recommendations 4 Background 7 Purpose of the Review 8 Working arrangements and governance 8 Delivering a service model for the future 8 Delivering a cardiac physiology service to quality standards 16 Developing a cardiac physiology workforce for the future 18 Commissioning for quality 20 Appendix 1: 23 Cardiac physiology services in summary Appendix 2: 27 Working arrangements and governance Appendix 3: 28 Award in Practical Electrocardiography (APECG) Appendix 4: 29 Proposed possible key performance indicators Appendix 5: 30 Current status of standards development across a range of cardiac physiology investigations Appendix 6: 32 Current training, accreditation and standards Appendix 7: 33 National Review of Cardiac Physiology Services - Modelling the Future Workforce References 34 Glossary 36 Acknowledgements 38 Strategic Review of Cardiac Physiology Services in England Page 2 Final Report: 12/05/2015 FOREWORD In 2013, the Department of Health published the Cardiovascular Outcomes Strategy, a call to action to the health and care systems, which set out ten key actions to deliver for patients with cardiovascular disease improvements in their health outcomes. Cardiac physiology services are key to delivering the improved treatment and care, which is the ambition of the Outcomes Strategy. This Strategic Review of Cardiac Physiology Services was set up to make recommendations to NHS England, Health Education England and across the health and care system about the innovations in service delivery, models of care and workforce configuration which are needed to transform patients’ experience of cardiovascular disease care.
    [Show full text]
  • Standardisation of Spirometry
    Eur Respir J 2005; 26: 319–338 DOI: 10.1183/09031936.05.00034805 CopyrightßERS Journals Ltd 2005 SERIES ‘‘ATS/ERS TASK FORCE: STANDARDISATION OF LUNG FUNCTION TESTING’’ Edited by V. Brusasco, R. Crapo and G. Viegi Number 2 in this Series Standardisation of spirometry M.R. Miller, J. Hankinson, V. Brusasco, F. Burgos, R. Casaburi, A. Coates, R. Crapo, P. Enright, C.P.M. van der Grinten, P. Gustafsson, R. Jensen, D.C. Johnson, N. MacIntyre, R. McKay, D. Navajas, O.F. Pedersen, R. Pellegrino, G. Viegi and J. Wanger CONTENTS AFFILIATIONS Background ............................................................... 320 For affiliations, please see Acknowledgements section FEV1 and FVC manoeuvre .................................................... 321 Definitions . 321 CORRESPONDENCE Equipment . 321 V. Brusasco Requirements . 321 Internal Medicine University of Genoa Display . 321 V.le Benedetto XV, 6 Validation . 322 I-16132 Genova Quality control . 322 Italy Quality control for volume-measuring devices . 322 Fax: 39 103537690 E-mail: [email protected] Quality control for flow-measuring devices . 323 Test procedure . 323 Received: Within-manoeuvre evaluation . 324 March 23 2005 Start of test criteria. 324 Accepted after revision: April 05 2005 End of test criteria . 324 Additional criteria . 324 Summary of acceptable blow criteria . 325 Between-manoeuvre evaluation . 325 Manoeuvre repeatability . 325 Maximum number of manoeuvres . 326 Test result selection . 326 Other derived indices . 326 FEVt .................................................................. 326 Standardisation of FEV1 for expired volume, FEV1/FVC and FEV1/VC.................... 326 FEF25–75% .............................................................. 326 PEF.................................................................. 326 Maximal expiratory flow–volume loops . 326 Definitions. 326 Equipment . 327 Test procedure . 327 Within- and between-manoeuvre evaluation . 327 Flow–volume loop examples. 327 Reversibility testing . 327 Method .
    [Show full text]
  • Cardiovascular Physiology
    BioMed Research International Cardiovascular Physiology Guest Editors: Karim Bendjelid, Bruno Levy, and Alain Broccard Cardiovascular Physiology BioMed Research International Cardiovascular Physiology Guest Editors: Karim Bendjelid, Bruno Levy, and Alain Broccard Copyright © 2015 Hindawi Publishing Corporation. All rights reserved. This is a special issue published in “BioMed Research International.” All articles are open access articles distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Contents Intensive Care Medicine Science: An Art Based on Applied Physiology?,KarimBendjelid,BrunoLevy, and Alain Broccard Volume 2015, Article ID 479134, 2 pages Patient-Specific Simulation of Coronary Artery Pressure Measurements: An In Vivo Three-Dimensional Validation Study in Humans, Panagiotis K. Siogkas, Michail I. Papafaklis, Antonis I. Sakellarios, Kostas A. Stefanou, Christos V. Bourantas, Lambros S. Athanasiou, Themis P. Exarchos, Katerina K. Naka, Lampros K. Michalis, Oberdan Parodi, and Dimitrios I. Fotiadis Volume 2015, Article ID 628416, 11 pages Spaceflight Affects Postnatal Development of the Aortic Wall in Rats, Shin-ichiro Katsuda, Masao Yamasaki, Hidefumi Waki, Masao Miyake, Hirotaka O-ishi, Kiyoaki Katahira, Tadanori Nagayama, Yukako Miyamoto, Masamitsu Hasegawa, Haruyuki Wago, Toshiyasu Okouchi, and Tsuyoshi Shimizu Volume 2014, Article ID 490428, 10 pages Angiotensin Converting Enzyme Inhibition Reduces
    [Show full text]
  • Reorganisation of Cardiac Physiological Services: a Position Statement
    Reorganisation of Cardiac Physiological Services: A Position Statement The career structure for healthcare science and the organisation of the profession has been extensively reconfigured in recent years. This has led to confusion and concern amongst those working in cardiac physiology. This paper represents the agreed position of the British Cardiovascular Society, British Society of Echocardiography, British Heart Rhythm Society and the Society for Cardiological Science and Technology (Henceforward referred to as the joint societies). The re‐organisation has three main work‐streams. Modernising scientific careers The formation of the Academy for Healthcare Science IQIPS process for departmental accreditation The joint societies welcome the focus on cardiac clinical science and the opportunities to create a more structured career for the profession, the potential for state registration and the focus on the quality of delivery that is so important to good patient care. Modernising Scientific Careers Modernising scientific careers (MSC) creates a clear distinction between the roles of healthcare practitioner, served by a practitioner training program (PTP) and clinical scientist, served by a scientist training program (STP). Roles that require advanced highly specialised scientific skill and are independently performed, analysed, interpreted and reported need “scientific” expertise and should be undertaken by scientists, typical examples in cardiology would include echocardiography, cardiac rhythm management device implantation and follow up, and cardiac electrophysiology. A clinical scientist will either have completed the STP program, or be working in an independent capacity in a highly specialised role, having also achieved certain specific academic attainments. For those in existing roles that map to a scientist role (as laid out in the Academy for Healthcare Science (AHCS) equivalence criteria), state registration through the academy is recommended.
    [Show full text]
  • Physicians by Categories
    OECD Health Statistics 2021 Definitions, Sources and Methods Physicians by categories Three main categories and eight sub-categories selected for the common module: Generalist medical practitioners (ISCO-08 code: 2211) General practitioners Other generalist (non-specialist) medical practitioners Specialist medical practitioners (ISCO-08 code: 2212) General paediatricians Obstetricians and gynaecologists Psychiatrists Medical group of specialists Surgical group of specialists Other specialists not elsewhere classified Medical doctors not further defined (ISCO-08 code: 2210) The breakdown by categories should be provided for practising physicians where possible. (If not possible, the data can be reported for professionally active physicians or physicians licensed to practise). Notes: - The following criteria are proposed in order to avoid double counting of doctors who have more than one specialty: 1) the predominant (main) area of practice of doctors; or 2) the last specialty for which doctors have received registration. - The number should be at the end of the calendar year. Generalist medical practitioners (ISCO-08 code: 2211) Generalist medical practitioners do not limit their practice to certain disease categories or methods of treatment, and may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families and communities. Inclusion - General practitioners - District medical doctors - therapists - Family medical practitioners - Primary health care physicians - Medical doctors
    [Show full text]
  • ANATOMY and PHYSIOLOGY a Listing of Materials Available at the Justice Institute Library
    ANATOMY AND PHYSIOLOGY A listing of materials available at the Justice Institute Library GENERAL BOOKS 100 Case Studies in Pathophysiology by Harold J. Bruyere, Jr. Philadelphia, PA: Lippincott Williams & Wilkins. (RB 113 B79 2009) A N Anatomy & Physiology by Kevin T. Patton and Gary A. Thibodeau. St. Louis, MO: Elsevier/Mosby. (QP 34.5 T49 2016) A T Anatomy & Physiology for the Prehospital Provider by Bob Elling and Kirsten M. Elling. Burlington, MA: Jones & Bartlett Learning. (QM 23.2 E415 2015) O M The Anatomy and Physiology Learning System by Edith Applegate. St. Louis, MO: Y Saunders/Elsevier. (QP 34.5 A67 2010) Anatomy & Physiology Made Incredibly Easy! Philadelphia, PA: Wolters Kluwer Health. A (QM 23.2 A53 2013) N The Anatomy Coloring Book by Wynn Kapit and Lawrence M. Elson. San Francisco, CA: Pearson. D (QM 25 K36 2013) Anatomy of the Human Body by Henry Gray. Philadelphia, PA: Lea & Febiger. (QM 23.3 G73 1985) P H Atlas of Human Anatomy by Frank H. Netter. Philadelphia, PA: Elsevier. (QM 25 N46 2019) Y An Atlas to Human Anatomy by Dennis Strete and Christopher H. Creek. Boston, MA: WCB/McGraw- S Hill. (QM 25 S767 2000) I O Barr’s The Human Nervous System: An Anatomical Viewpoint by John A. Kiernan and Nagalingam Rajakumar. Philadelphia, PA: Wolters Kluwer/Lippincott Williams & Wilkins. (QM 451 B27 2014) L O Berne & Levy Principles of Physiology edited by Matthew N. Levy, Bruce M. Koeppen, and Bruce A. Stanton. Philadelphia, PA: Elsevier Mosby. (QP 34.5 P744 2006) G Y Cardiopulmonary Anatomy & Physiology: Essentials of Respiratory Care by Terry Des Jardins.
    [Show full text]
  • ARTP Statement on Pulmonary Function Testing 2020
    Guidelines BMJ Open Resp Res: first published as 10.1136/bmjresp-2020-000575 on 5 July 2020. Downloaded from ARTP statement on pulmonary function testing 2020 Karl Peter Sylvester,1,2 Nigel Clayton,3 Ian Cliff,4 Michael Hepple,4 Adrian Kendrick,5 Jane Kirkby,6 Martin Miller,7 Alan Moore,8 Gerrard Francis Rafferty,9 Liam O'Reilly,10 Joanna Shakespeare,10 Laurie Smith ,6,11 Trefor Watts,12 Martyn Bucknall,13 Keith Butterfield14 To cite: Sylvester KP, ABSTRACT UK. These recommendations set out the Clayton N, Cliff I, et al. ARTP The Association for Respiratory Technology & Physiology requirements and considerations that need statement on pulmonary (ARTP) last produced a statement on the performance to be made in terms of environmental and function testing 2020. of lung function testing in 1994. At that time the focus patient factors that may influence both the BMJ Open Resp Res was on a practical statement for people working in lung 2020; :e000575. doi:10.1136/ performance and interpretation of lung 7 function laboratories. Since that time there have been bmjresp-2020-000575 many technological advances and alterations to best function tests. They also incorporate proce- practice in the measurement and interpretation of lung dures to ensure quality assured diagnostic Received 6 February 2020 function assessments. In light of these advances an update investigations that include those associated Revised 11 February 2020 was warranted. ARTP, therefore, have provided within Accepted 14 February 2020 with equipment, the healthcare professional this document, where available, the most up-to- da te and conducting the assessments and the results evidence-based recommendations for the most common achieved by the subject.
    [Show full text]
  • Positron Emission Tomography: Molecular Imaging of Biological Processes - Juhani Knuuti, Heikki Minn, and Juha Rinne
    PHYSIOLOGY AND MAINTENANCE – Vol. I – Positron Emission Tomography: Molecular Imaging of Biological Processes - Juhani Knuuti, Heikki Minn, and Juha Rinne POSITRON EMISSION TOMOGRAPHY: MOLECULAR IMAGING OF BIOLOGICAL PROCESSES Juhani Knuuti, Heikki Minn, and Juha Rinne Turku University Central Hospital, Finland Keywords: functional imaging, positron emission tomography, metabolism, brain receptors, cancer, genes Contents 1. Introduction: Principles of PET 2. Radiochemistry 3. Drug Development, Radiolabeled Drugs, and PET 3.1. Pharmacodynamic Studies 3.2. Pharmacokinetic Studies 4. Brain Receptors and Neurotransmission 5. Perfusion Imaging 6. Metabolic Imaging 6.1. Glucose Metabolism 6.2. Free Fatty Acid (FFA) Metabolism 6.3. Oxidative Metabolism 7. Clinical Applications of PET 7.1. PET in Oncology 7.2. Metabolic Imaging 7.3. PET in Brain Diseases 8. Imaging Gene Expression in vivo using PET Glossary Bibliography Biographical Sketches Summary Positron emission tomography (PET) is an unsurpassed method for imaging human biochemical and physiological processes in vivo. Unlimited numbers of natural substrates,UNESCO substrate analogs, and drugs –can beEOLSS labeled for use with PET. This labeling does not change their chemical or biological properties. Minute amounts of biologically active compounds are labeled with positron emitting radionuclides and then administered to SAMPLEthe subjects. CHAPTERS The temporal and spatial distribution of these tracers within the body is measured with PET. PET combined with tracer kinetic models measures blood flow, membrane transport, metabolism, ligand receptor interactions, and, recently, also gene expression, noninvasively and quantitatively, in humans. PET has also been used extensively to study cellular metabolism in the brain, heart, and malignant tumors. 1. Introduction: Principles of PET ©Encyclopedia of Life Support Systems (EOLSS) PHYSIOLOGY AND MAINTENANCE – Vol.
    [Show full text]
  • PATHFINDER on PHYSIOLOGY Guide on the Literature and Resources of the Library
    PATHFINDER ON PHYSIOLOGY Guide on the literature and resources of the library Prepared by Anna Rita L. Alomo, Head Librarian, Health Sciences Library OUTLINE Scope Note 1 Books 1 Online Articles 5 Electronic Resources 7 Scope Note: Sources on the normal functions of the different organ systems of the body, the pathophysiologic mechanisms of diseases usually seen in the community and the physiologic principles involved in the treatment of diseases. Books: Adler's physiology of the eye. (2011). London ; New York : Saunders/Elsevier. [RE67 .Ad59 2011] Anatomy & physiology : an incredibly visual! pocket guide. (2010). Philadelphia, Pa.: Wolters Kluwer Health/Lippincott Williams &Wilkins. [QM25 .An16 2010] Anatomy & physiology made incredibly easy!. (2009). Philadelphia : Wolters Kluwer Health/Lippincott Williams &Wilkins. [QP41 .An16 2009] Anderson, P. D. (2009). Human anatomy and physiology coloring workbook and study guide. Boston: Jones and Bartlett. [QM30 .An24 2009] Applegate, E. J. (2011). The anatomy and physiology learning system. St. Louis, Mo.: Saunders/Elsevier. [QP34.5 .Ap52 2011] Applied basic science for basic surgical training. (2008). New York : Churchill Livingstone. [RD31.5 .Ap58 2008] Atlas of pathophysiology / Anatomical Chart Co. (2010). Philadelphia : Wolters Kluwer Health/Lippincott Williams &Wilkins. [RB113 .At65 2010] ~ 1 ~ Beachey, W. (2013). Respiratory care anatomy and physiology : foundations for clinical practice. St.Louis, Mo. ; London : Mosby. [QP121 .B353 2013] Berne & Levy physiology. (2010). Philadelphia, PA : Mosby/Elsevier. [QP34.5 .B457 2010] Braun, C. A. (2011). Pathophysiology : a clinical approach. Philadelphia : Wolters Kluwer/Lippincott Williams & Wilkins Health. [RB113 .B738p 2011] Braun, C. A.(2011). Study guide for Pathophysiology : a clinical approach. Philadelphia, PA : Wolters Kluwer/Lippincott Williams & Wilkins.
    [Show full text]