DOCSLIB.ORG
  • Sign Up
  • Log In
  • Upload
  • Sign Up
  • Log In
  • Upload
  • Home
  • »  Tags
  • »  Synthetic lethality

Synthetic lethality

  • DNA Repair and Synthetic Lethality

    DNA Repair and Synthetic Lethality

  • The Tumor Therapy Landscape of Synthetic Lethality

    The Tumor Therapy Landscape of Synthetic Lethality

  • Mutational Signatures Are Markers of Drug Sensitivity of Cancer Cells

    Mutational Signatures Are Markers of Drug Sensitivity of Cancer Cells

  • Approaches to Identifying Synthetic Lethal Interactions in Cancer

    Approaches to Identifying Synthetic Lethal Interactions in Cancer

  • RAD51C-Deficient Cancer Cells Are Highly Sensitive to the PARP Inhibitor Olaparib

    RAD51C-Deficient Cancer Cells Are Highly Sensitive to the PARP Inhibitor Olaparib

  • Synthetic Lethal Screening in the Mammalian Central Nervous System Identifies Gpx6 As a Modulator of Huntington’S Disease

    Synthetic Lethal Screening in the Mammalian Central Nervous System Identifies Gpx6 As a Modulator of Huntington’S Disease

  • Prognosis, Biology, and Targeting of TP53 Dysregulation in Multiple Myeloma

    Prognosis, Biology, and Targeting of TP53 Dysregulation in Multiple Myeloma

  • Loss-Of-Function Genetic Screens As a Tool to Improve the Diagnosis and Treatment of Cancer

    Loss-Of-Function Genetic Screens As a Tool to Improve the Diagnosis and Treatment of Cancer

  • PALB2 Mutations and Breast-Cancer Risk Michele K

    PALB2 Mutations and Breast-Cancer Risk Michele K

  • Synthetic Lethality of a Cell-Penetrating Anti-RAD51 Antibody in PTEN-Deficient Melanoma and Glioma Cells

    Synthetic Lethality of a Cell-Penetrating Anti-RAD51 Antibody in PTEN-Deficient Melanoma and Glioma Cells

  • Genetic Screening Approaches to Cancer Driver Characterization and Synthetic Lethal Target Discovery

    Genetic Screening Approaches to Cancer Driver Characterization and Synthetic Lethal Target Discovery

  • ATM-Deficient Cancers Provide New Opportunities for Precision Oncology

    ATM-Deficient Cancers Provide New Opportunities for Precision Oncology

  • A Synthetic Lethal Screen Identifies ATR-Inhibition As a Novel Therapeutic Approach for POLD1 -Deficient Cancers

    A Synthetic Lethal Screen Identifies ATR-Inhibition As a Novel Therapeutic Approach for POLD1 -Deficient Cancers

  • Evolution of Cancer Genomics and Its Clinical Implications

    Evolution of Cancer Genomics and Its Clinical Implications

  • Oncogeneticsoncogenetics Clinical Genetics

    Oncogeneticsoncogenetics Clinical Genetics

  • ATM Mutations in Cancer: Therapeutic Implications Michael Choi, Thomas Kipps, and Razelle Kurzrock

    ATM Mutations in Cancer: Therapeutic Implications Michael Choi, Thomas Kipps, and Razelle Kurzrock

  • Synergistic Targeting and Resistance to PARP Inhibition in DNA Damage

    Synergistic Targeting and Resistance to PARP Inhibition in DNA Damage

  • Elaborating the Mechanism of PARP Synthetic Lethality Following ATM

    Elaborating the Mechanism of PARP Synthetic Lethality Following ATM

Top View
  • Regulation of DNA Damage Response and Homologous Recombination Repair by Microrna in Human Cells Exposed to Ionizing Radiation
  • CRISPR Screens in Synthetic Lethality and Combinatorial Therapies for Cancer
  • Drug Driven Synthetic Lethality: Bypassing Tumor Cell Genetics with a Combination of Dbait and PARP Inhibitors
  • RAD51-Mediated DNA Homologous Recombination Is Independent of PTEN Mutational Status
  • Synthetic Lethality-Mediated Precision Oncology Via the Tumor Transcriptome
  • Synthetic Lethality: Beating Cancer at Its Own Game Jane De Lartigue, Phd
  • ATM and ATR As Therapeutic Targets in Cancer
  • Breast Cancer Predisposition Genes and Synthetic Lethality
  • Exploiting Synthetic Lethal Vulnerabilities for Cancer Therapy
  • Compound F779-0434 Causes Synthetic Lethality in BRCA2-Deficient Cancer Cells by Disrupting RAD52– Cite This: RSC Adv.,2018,8, 18859 Ssdna Association†
  • CIP2A Is a Prime Synthetic-Lethal Target for BRCA-Mutated Cancers
  • Mir-509-3 Augments the Synthetic Lethality of Parpi by Regulating HR
  • ATM Loss Leads to Synthetic Lethality in BRCA1 BRCT Mutant Mice Associated with Exacerbated Defects in Homology-Directed Repair
  • Epigenetic Synthetic Lethality Approaches in Cancer Therapy Haoshen Yang, Wei Cui* and Lihui Wang*
  • ATM Signalling and Cancer
  • What's Next After PARP Inhibitors for BRCA Mutated Cancers?
  • Synthetic Lethality As an Engine for Cancer Drug Target Discovery
  • Inhibition of DNA Repair in Cancer Therapy: Toward a Multi-Target Approach


© 2024 Docslib.org    Feedback