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MDM4
MDM4 (MDMX) and Its Transcript Variants
Expression of the P53 Inhibitors MDM2 and MDM4 As Outcome
Mir-661 Downregulates Both Mdm2 and Mdm4 to Activate P53
The P53 Pathway Is Altered in Most, If Not All, Tumours. in More Than Half Of
MDM4 Contributes to the Increased Risk of Glioma Susceptibility in Han
Anti-USP7 Antibody
Mdm2 and Mdmx RING Domains Play Distinct Roles in the Regulation of P53 Responses: a Comparative Study of Mdm2 and Mdmx RING Domains in U2OS Cells
Regulation of MDM4 (MDMX) Function by P76mdm2: a New Facet in the Control of P53 Activity
Intra Molecular Interactions in the Regulation of P53 Pathway
The P53–Mdm2 Interaction and the E3 Ligase Activity of Mdm2/Mdm4 Are Conserved from Lampreys to Humans
MDM4 Is an Essential Disease Driver Targeted by 1Q Gain in Burkitt
Structural Basis for High-Affinity Peptide Inhibition of P53 Interactions with MDM2 and MDMX
Original Article Mir-1205 Functions As a Tumor Suppressor by Disconnecting the Synergy Between KRAS and MDM4/E2F1 in Non-Small Cell Lung Cancer
Activation of the P53 Pathway by Small-Molecule- Induced MDM2 and MDMX Dimerization
Rare MDM4 Gene Amplification in Colorectal Cancer: the Principle of a Mutually Exclusive Relationship Between MDM Alteration and TP53 Inactivation Is Not Applicable
Alternative Splicing of Mdm4 in Human Melanoma
Zytolight ® SPEC MDM4/1P12 Dual Color Probe
Integrative Genomic Analysis of Mouse and Human Hepatocellular Carcinoma
Top View
Phenotype Informatics
Resistance Mechanisms to TP53-MDM2 Inhibition Identified by in Vivo Piggybac Transposon Mutagenesis − − Screen in an Arf / Mouse Model
Selective USP7 Inhibition Elicits Cancer Cell Killing Through a P53- Dependent Mechanism Nathan J
Maternal Snps in the P53 Pathway: Risk Factors for Trisomy 21?
Heterodimerization of Mdm2 and Mdm4 Is Critical for Regulating P53 Activity During Embryogenesis but Dispensable for P53 and Mdm2 Stability
Simultaneous Measurement of P53:Mdm2 and P53:Mdm4 Protein- Protein Interactions in Whole Cells Using Fuorescence Labelled Foci Y
MDM2 and MDM4 Are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors Thomas P
Role of Mdm4 in Drug Sensitivity of Breast Cancer Cells
A Genetic Variant of MDM4 Influences Regulation by Multiple Micrornas In
An Analysis of MDM4 Alternative Splicing and Effects Across Cancer Cell Lines
A Novel Therapeutic Strategy to Reactivate P53 in Hepatoblastoma Sarah E
CRISPR Enriches for Cells with Mutations in a P53-Related Interactome, And
Targeting the MDM2/MDM4 Interaction Interface As a Promising
Mdm2, but Not Mdm4, Protects Terminally Differentiated Smooth Muscle Cells from P53-Mediated Caspase-3- Independent Cell Death
Molecular Pathways: Targeting Mdm2 and Mdm4 in Cancer Therapy
Dual Inhibition of MDM2 and MDM4 in Virus-Positive Merkel Cell
Protein MDM4
Reciprocal Regulation of Mir-1205 and E2F1 Modulates Progression Of
White Shark Genome Reveals Ancient Elasmobranch Adaptations Associated with Wound Healing and the Maintenance of Genome Stability
Genome-Wide Association Study Identifies Zonisamide Responsive
Dying to Survive—The P53 Paradox
The RING Domain of Mdm2 Can Inhibit Cell Proliferation1
Activation of the P53-MDM4 Regulatory Axis Defines the Anti-Tumour
MDM4 As a Prognostic Factor for Patients with Gastric Cancer With
Regulation of PRMT5–MDM4 Axis Is Critical in the Response to CDK4/6 Inhibitors in Melanoma
Degradation of the Oncoprotein Mdmx in Neurodegenerative States: Evidence for a Pro-Survival Role of Mdmx in Neurons
Enhanced G1 Arrest and Apoptosis Via MDM4/MDM2 Double Knockdown and MEK Inhibition in Wild‑Type TP53 Colon and Gastric Cancer Cells with Aberrant KRAS Signaling
MDM4 Is Targeted by 1Q Gain and Drives Disease in Burkitt Lymphoma
The MDMX (MDM4) Oncoprotein As a Therapeutic Target and Determinant
Predicting Human Disease Mutations and Identifying Drug Targets from Mouse Gene Knockout Phenotyping Campaigns Robert Brommage1,*, David R
MDM2 and MDM4 Are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors
Advances in the Development Ubiquitin-Specific Peptidase (USP)
Dual Inhibition of MDM2 and MDM4 in Virus-Positive Merkel Cell
Targeting Mdm2 and Mdm4 in Cancer Therapy
Structure of the MDM2/MDMX RING Domain Heterodimer Reveals Dimerization Is Required for Their Ubiquitylation in Trans