MDM4 Is an Essential Disease Driver Targeted by 1Q Gain in Burkitt
bioRxiv preprint doi: https://doi.org/10.1101/289363; this version posted April 9, 2018. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. All rights reserved. No reuse allowed without permission. MDM4 is an essential disease driver targeted by 1q gain in Burkitt lymphoma Jennifer Hüllein1,2, Mikołaj Słabicki1*, Maciej Rosolowski3, Alexander Jethwa1,2, Stefan Habringer4, Katarzyna Tomska1, Roma Kurilov5, Junyan Lu6, Sebastian Scheinost1, Rabea Wagener7,8, Zhiqin Huang9, Marina Lukas1, Olena Yavorska6, Hanne Helferich10, René Scholtysik11, Kyle Bonneau12, Donato Tedesco12, Ralf Küppers11, Wolfram Klapper13, Christiane Pott14, Stephan Stilgenbauer10, Birgit Burkhardt15, Markus Löffler3, Lorenz Trümper16, Michael Hummel17, Benedikt Brors5, Marc Zapatka9, Reiner Siebert7,8, MMML consortium, Ulrich Keller4, Wolfgang Huber6, Markus Kreuz3, and Thorsten Zenz1,18,19** 1Molecular Therapy in Hematology and Oncology & Department of Translational Oncology, NCT and DKFZ, Heidelberg, Germany 2Faculty of Biosciences, Heidelberg University, Heidelberg, Germany 3Department for Statistics and Epidemiology, Institute for Medical Informatics, Leipzig, Germany 4III. Medical Department of Hematology and Medical Oncology, Technical University of Munich, Germany 5Division of Applied Bioinformatics, DKFZ, Heidelberg, Germany 6European Molecular Biology Laboratory (EMBL), Heidelberg, Germany 7Institute of Human Genetics, Ulm University & Ulm University Medical Center, Germany 8Institute of Human Genetics, University
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