Supplementary Material 1 of the Manuscript Entitled
Supplementary material 1 of the manuscript entitled:
HYPERTENSION IN CHILDREN AND ADOLESCENTS
ATTENDING A LIPID CLINIC
by
Francesco Martino1,MD, Paolo Emilio Puddu2,MD, FESC, FACC, Giuseppe Pannarale2,MD, Chiara Colantoni1,MD, Eliana Martino1,MD, Cristina Zanoni1, Francesco Barillà2,MD
1Lipid Research, Dipartimento di Pediatria e Neuropsichiatria Infantile;2Dipartimento di Scienze Cardiovascolari, Respiratorie, Nefrologiche, Anestesiologiche e Geriatriche, “Sapienza” Università di Roma, Rome, Italy
Please note that to interpret the following hypertension-corrected multiple correlation section (pages 2 to 8), the framed corresponding table from Italian acronyms to fully disclosed English significances, should be used.
SexEta
BMI
Ins
kg
h
cv_h
Vita
Fianc
Bracc
PAS
PAD
PASp
PADp
PASm
PADm
CT
HC
HDL
nHDL
TG
LDL
BMIp
BMIm
glicemia
Insp
Insm
Vitap
Fiancp
Braccp
Vitam
Fiancm
Braccm
Creatinina
N_ureico
Uricemia
pcr / Gender
Age
Body Mass Index
Insulin level
Weight
Height
Waist-hip ratio
Waist circumference
Hip circumference
Middle-upper arm circumference
Systolic Blood Pressure
Diastolic Blood Pressure
Systolic Blood Pressure of the fathers
Diastolic Blood Pressure of the fathers
Systolic Blood Pressure of the mothers
Diastolic Blood Pressure of the mothers
Total cholesterol
Hypercholesterolemic subjects
HDL cholesterol
Non-HDL cholesterol
Triglycerides
LDL cholesterol
Body Mass Index of the fathers
Body Mass Index of the mothers
Fasting blood glucose
Insulin level of the fathers
Insulin level of the mothers
Waist circumference of the fathers
Hip circumference of the fathers
Middle-upper arm circumference of the fathers
Waist circumference of the mothers
Hip circumference of the mothers
Middle-upper arm circumference of the mothers
Creatinine
Blood urea nitrogen (BUN)
Uric Acid
High sensitivity C-reactive protein (hsCRP)
Correlation Report
Page/Date/Time 1 2/26/2013 4:00:20 PM
Database
Controlled For: GroupHT1
Pearson Correlations Section (Pair-Wise Deletion)
Sex Eta BMI Ins kg h
Sex 1.000000 0.077460 0.076786 -0.092728 0.116133 0.079901
Eta 0.077460 1.000000 0.329086 0.408524 0.690838 0.861101
BMI 0.076786 0.329086 1.000000 0.590548 0.757246 0.379434
Ins -0.092728 0.408524 0.590548 1.000000 0.658304 0.471354
kg 0.116133 0.690838 0.757246 0.658304 1.000000 0.843581
h 0.079901 0.861101 0.379434 0.471354 0.843581 1.000000
cv_h 0.173931 -0.095859 0.694009 0.383186 0.377964 -0.041695
Vita 0.188406 0.503172 0.823426 0.627642 0.885930 0.640050
Fianc 0.074559 0.539564 0.796570 0.635241 0.895678 0.691644
Bracc 0.074787 0.514546 0.803860 0.624622 0.882686 0.665486
PAS 0.102624 0.318209 0.251194 0.232998 0.298775 0.271476
PAD -0.021261 0.092722 0.066554 0.117777 0.126955 0.112047
PASp -0.158792 0.032549 0.063699 0.140611 0.044350 0.026493
PADp -0.026634 0.031399 0.083220 0.087887 0.087267 0.080910
PASm -0.073577 -0.017566 0.032769 0.034677 0.011288 0.019573
PADm -0.046016 0.048735 0.040767 0.029280 0.047622 0.067975
CT -0.190990 -0.097923 -0.100621 -0.114697 -0.205249 -0.184654
HC -0.099541 -0.078366 -0.016613 -0.083841 -0.124180 -0.160786
HDL -0.066033 -0.094036 -0.300156 -0.290222 -0.305274 -0.174634
nHDL -0.171764 -0.068507 -0.004218 -0.021660 -0.108424 -0.130066
TG 0.006232 0.107616 0.340373 0.338803 0.281492 0.141566
LDL -0.167093 -0.091241 -0.064176 -0.079841 -0.161500 -0.159619
BMIp -0.025234 0.031647 0.339857 0.216762 0.231143 0.065541
BMIm 0.003336 -0.004355 0.288267 0.165597 0.202862 0.045246
glicemia 0.109976 0.153730 0.201035 0.177834 0.183538 0.133526
Insp 0.034720 0.139741 0.322216 0.265642 0.362397 0.206977
Insm 0.112712 0.007258 0.144884 0.062540 0.114405 0.048540
Vitap -0.042710 0.043898 0.261274 0.200531 0.194006 0.075983
Fiancp -0.038808 0.012723 0.155953 0.047758 0.063870 -0.000768
Braccp 0.019429 0.069125 0.157149 0.173968 0.149668 0.072619
Vitam -0.011343 -0.030777 0.280004 0.211330 0.192611 0.030466
Fiancm -0.019051 -0.041695 0.207955 0.092140 0.114000 0.002375
Braccm 0.036608 -0.028994 0.128263 0.065465 0.078723 -0.004962
Creatinina -0.025938 0.083354 0.057896 0.040684 0.114036 0.115711
N_ureico -0.122313 0.001515 0.010298 0.025139 0.018425 0.018582
Uricemia -0.080362 -0.017026 0.031626 0.003284 0.014466 -0.001761
pcr 0.022458 -0.056677 0.155275 0.072354 0.039485 -0.060574
Cronbachs Alpha = 0.030471 Standardized Cronbachs Alpha = 0.808706
Correlation Report
Page/Date/Time 2 2/26/2013 4:00:20 PM
Database
Controlled For: GroupHT1
Pearson Correlations Section (Pair-Wise Deletion)
cv_h Vita Fianc Bracc PAS PAD
Sex 0.173931 0.188406 0.074559 0.074787 0.102624 -0.021261
Eta -0.095859 0.503172 0.539564 0.514546 0.318209 0.092722
BMI 0.694009 0.823426 0.796570 0.803860 0.251194 0.066554
Ins 0.383186 0.627642 0.635241 0.624622 0.232998 0.117777
kg 0.377964 0.885930 0.895678 0.882686 0.298775 0.126955
h -0.041695 0.640050 0.691644 0.665486 0.271476 0.112047
cv_h 1.000000 0.705293 0.623301 0.614839 0.103951 0.044748
Vita 0.705293 1.000000 0.933864 0.914097 0.249828 0.110385
Fianc 0.623301 0.933864 1.000000 0.924570 0.243037 0.089112
Bracc 0.614839 0.914097 0.924570 1.000000 0.236178 0.086227
PAS 0.103951 0.249828 0.243037 0.236178 1.000000 0.433302
PAD 0.044748 0.110385 0.089112 0.086227 0.433302 1.000000
PASp 0.020246 0.016340 0.032589 0.032767 0.012493 0.074231
PADp 0.041019 0.072126 0.088782 0.082571 0.042277 0.203428
PASm 0.029733 0.023794 0.048940 0.062617 -0.034136 -0.083739
PADm 0.015819 0.043984 0.044044 0.065824 -0.024513 0.008093
CT -0.098826 -0.176053 -0.205660 -0.149576 0.023625 0.052681
HC -0.015785 -0.104880 -0.139881 -0.091882 0.109874 0.089539
HDL -0.315132 -0.370640 -0.338394 -0.334137 -0.058352 -0.041832
nHDL 0.002478 -0.057621 -0.098062 -0.042715 0.042893 0.066927
TG 0.345149 0.377664 0.344644 0.324278 0.039979 0.001352
LDL -0.004321 -0.119758 -0.133654 -0.077172 0.048427 0.082768
BMIp 0.286064 0.273231 0.269716 0.267468 0.079075 0.044688
BMIm 0.307138 0.287930 0.293773 0.273375 0.102268 -0.097255
glicemia 0.058820 0.160546 0.166879 0.143451 0.099855 -0.160008
Insp 0.158778 0.293987 0.268393 0.295572 0.114982 0.026327
Insm 0.155656 0.146996 0.153732 0.160493 0.138272 0.048003
Vitap 0.205273 0.218749 0.208499 0.191919 0.060128 0.011751
Fiancp 0.092355 0.066750 0.075926 0.064276 0.020306 0.002779
Braccp 0.183320 0.205698 0.187482 0.152674 0.069431 -0.052847
Vitam 0.322277 0.288668 0.276042 0.255336 0.085162 -0.039316
Fiancm 0.183345 0.158191 0.178542 0.187393 0.081457 0.026491
Braccm 0.200108 0.155801 0.154530 0.133491 0.050083 -0.110585
Creatinina -0.017222 0.063525 0.076187 0.066843 0.001793 -0.000971
N_ureico -0.028044 -0.004883 0.015422 0.049644 -0.014354 0.050603
Uricemia 0.016582 0.009766 0.018389 0.054760 0.053085 0.113152
pcr 0.160999 0.084855 0.066999 0.094400 0.054305 -0.046967
Cronbachs Alpha = 0.030471 Standardized Cronbachs Alpha = 0.808706
Correlation Report
Page/Date/Time 3 2/26/2013 4:00:20 PM
Database
Controlled For: GroupHT1
Pearson Correlations Section (Pair-Wise Deletion)
PASp PADp PASm PADm CT HC
Sex -0.158792 -0.026634 -0.073577 -0.046016 -0.190990 -0.099541
Eta 0.032549 0.031399 -0.017566 0.048735 -0.097923 -0.078366
BMI 0.063699 0.083220 0.032769 0.040767 -0.100621 -0.016613
Ins 0.140611 0.087887 0.034677 0.029280 -0.114697 -0.083841
kg 0.044350 0.087267 0.011288 0.047622 -0.205249 -0.124180
h 0.026493 0.080910 0.019573 0.067975 -0.184654 -0.160786
cv_h 0.020246 0.041019 0.029733 0.015819 -0.098826 -0.015785
Vita 0.016340 0.072126 0.023794 0.043984 -0.176053 -0.104880
Fianc 0.032589 0.088782 0.048940 0.044044 -0.205660 -0.139881
Bracc 0.032767 0.082571 0.062617 0.065824 -0.149576 -0.091882
PAS 0.012493 0.042277 -0.034136 -0.024513 0.023625 0.109874
PAD 0.074231 0.203428 -0.083739 0.008093 0.052681 0.089539
PASp 1.000000 0.630725 0.095643 0.085584 -0.001349 -0.042122
PADp 0.630725 1.000000 0.113172 0.204257 -0.049321 -0.061154
PASm 0.095643 0.113172 1.000000 0.586766 0.051270 0.015978
PADm 0.085584 0.204257 0.586766 1.000000 0.042994 -0.005806
CT -0.001349 -0.049321 0.051270 0.042994 1.000000 0.746306
HC -0.042122 -0.061154 0.015978 -0.005806 0.746306 1.000000
HDL -0.023456 -0.070864 -0.048441 -0.112797 0.197013 0.189220
nHDL 0.006270 -0.026837 0.067638 0.080215 0.947837 0.693678
TG -0.058560 -0.030620 0.051158 0.172476 0.086319 0.068040
LDL 0.035606 -0.002395 0.067658 0.063917 0.941032 0.692473
BMIp 0.240184 0.148243 0.129374 0.108570 -0.099512 -0.053922
BMIm 0.029953 0.057784 0.210825 0.092991 -0.051100 -0.056441
glicemia 0.013529 -0.026441 0.062802 0.089534 -0.020846 0.039339
Insp 0.114822 0.071432 -0.074621 0.053261 -0.106798 -0.076821
Insm 0.002566 0.088864 0.053720 -0.018099 -0.018075 -0.030038
Vitap 0.210321 0.160563 0.095811 0.129410 -0.120169 -0.063015
Fiancp 0.089069 0.060391 0.046212 0.109050 -0.052788 -0.000943
Braccp 0.124269 0.139234 0.039863 0.055303 -0.041275 -0.003327
Vitam -0.054984 0.048409 0.042924 0.010793 -0.038860 0.011771
Fiancm -0.048050 0.011604 0.084410 0.012109 -0.025437 0.017844
Braccm -0.006462 0.020901 0.073915 0.003907 -0.010177 0.059625
Creatinina -0.056350 0.006431 0.136534 0.116763 -0.086789 -0.115678
N_ureico 0.031005 0.093739 -0.074356 -0.044916 0.033399 -0.012238
Uricemia 0.069554 0.140649 0.014024 -0.021319 0.029193 0.035195
pcr 0.055561 0.048124 0.041125 -0.010039 0.050185 0.045257
Cronbachs Alpha = 0.030471 Standardized Cronbachs Alpha = 0.808706
Correlation Report
Page/Date/Time 4 2/26/2013 4:00:20 PM
Database
Controlled For: GroupHT1
Pearson Correlations Section (Pair-Wise Deletion)
HDL nHDL TG LDL BMIp BMIm
Sex -0.066033 -0.171764 0.006232 -0.167093 -0.025234 0.003336
Eta -0.094036 -0.068507 0.107616 -0.091241 0.031647 -0.004355
BMI -0.300156 -0.004218 0.340373 -0.064176 0.339857 0.288267
Ins -0.290222 -0.021660 0.338803 -0.079841 0.216762 0.165597
kg -0.305274 -0.108424 0.281492 -0.161500 0.231143 0.202862
h -0.174634 -0.130066 0.141566 -0.159619 0.065541 0.045246
cv_h -0.315132 0.002478 0.345149 -0.004321 0.286064 0.307138
Vita -0.370640 -0.057621 0.377664 -0.119758 0.273231 0.287930
Fianc -0.338394 -0.098062 0.344644 -0.133654 0.269716 0.293773
Bracc -0.334137 -0.042715 0.324278 -0.077172 0.267468 0.273375
PAS -0.058352 0.042893 0.039979 0.048427 0.079075 0.102268
PAD -0.041832 0.066927 0.001352 0.082768 0.044688 -0.097255
PASp -0.023456 0.006270 -0.058560 0.035606 0.240184 0.029953
PADp -0.070864 -0.026837 -0.030620 -0.002395 0.148243 0.057784
PASm -0.048441 0.067638 0.051158 0.067658 0.129374 0.210825
PADm -0.112797 0.080215 0.172476 0.063917 0.108570 0.092991
CT 0.197013 0.947837 0.086319 0.941032 -0.099512 -0.051100
HC 0.189220 0.693678 0.068040 0.692473 -0.053922 -0.056441
HDL 1.000000 -0.125771 -0.441407 -0.044094 -0.074199 -0.171644
nHDL -0.125771 1.000000 0.230878 0.966578 -0.076567 0.004117
TG -0.441407 0.230878 1.000000 0.039794 -0.008716 0.123184
LDL -0.044094 0.966578 0.039794 1.000000 -0.070853 -0.017343
BMIp -0.074199 -0.076567 -0.008716 -0.070853 1.000000 0.332003
BMIm -0.171644 0.004117 0.123184 -0.017343 0.332003 1.000000
glicemia 0.010126 -0.024397 0.141898 -0.069307 0.143550 0.113546
Insp -0.173167 -0.051754 0.118606 -0.085794 0.348681 0.203474
Insm -0.030036 -0.008504 0.020756 -0.005647 0.164570 0.100295
Vitap -0.072125 -0.098136 -0.005456 -0.097943 0.826294 0.232482
Fiancp 0.015520 -0.058452 -0.089435 -0.037305 0.606791 0.075666
Braccp -0.105695 -0.007401 0.176871 -0.042762 0.372043 0.250512
Vitam -0.131746 0.003523 0.115608 -0.018862 0.221186 0.741521
Fiancm -0.022032 -0.018563 -0.039930 -0.012133 0.226547 0.543679
Braccm -0.041815 0.003292 0.060664 -0.009202 0.108393 0.422965
Creatinina -0.035167 -0.076376 0.072212 -0.088441 -0.033064 -0.008037
N_ureico -0.028980 0.043253 -0.024371 0.045915 0.018357 0.015087
Uricemia -0.041033 0.042887 0.006179 0.043722 0.027917 -0.006816
pcr -0.144479 0.097765 0.023771 0.098360 0.126679 0.100814
Cronbachs Alpha = 0.030471 Standardized Cronbachs Alpha = 0.808706
Correlation Report
Page/Date/Time 5 2/26/2013 4:00:20 PM
Database
Controlled For: GroupHT1
Pearson Correlations Section (Pair-Wise Deletion)
glicemia Insp Insm Vitap Fiancp Braccp
Sex 0.109976 0.034720 0.112712 -0.042710 -0.038808 0.019429
Eta 0.153730 0.139741 0.007258 0.043898 0.012723 0.069125
BMI 0.201035 0.322216 0.144884 0.261274 0.155953 0.157149
Ins 0.177834 0.265642 0.062540 0.200531 0.047758 0.173968
kg 0.183538 0.362397 0.114405 0.194006 0.063870 0.149668
h 0.133526 0.206977 0.048540 0.075983 -0.000768 0.072619
cv_h 0.058820 0.158778 0.155656 0.205273 0.092355 0.183320
Vita 0.160546 0.293987 0.146996 0.218749 0.066750 0.205698
Fianc 0.166879 0.268393 0.153732 0.208499 0.075926 0.187482
Bracc 0.143451 0.295572 0.160493 0.191919 0.064276 0.152674
PAS 0.099855 0.114982 0.138272 0.060128 0.020306 0.069431
PAD -0.160008 0.026327 0.048003 0.011751 0.002779 -0.052847
PASp 0.013529 0.114822 0.002566 0.210321 0.089069 0.124269
PADp -0.026441 0.071432 0.088864 0.160563 0.060391 0.139234
PASm 0.062802 -0.074621 0.053720 0.095811 0.046212 0.039863
PADm 0.089534 0.053261 -0.018099 0.129410 0.109050 0.055303
CT -0.020846 -0.106798 -0.018075 -0.120169 -0.052788 -0.041275
HC 0.039339 -0.076821 -0.030038 -0.063015 -0.000943 -0.003327
HDL 0.010126 -0.173167 -0.030036 -0.072125 0.015520 -0.105695
nHDL -0.024397 -0.051754 -0.008504 -0.098136 -0.058452 -0.007401
TG 0.141898 0.118606 0.020756 -0.005456 -0.089435 0.176871
LDL -0.069307 -0.085794 -0.005647 -0.097943 -0.037305 -0.042762
BMIp 0.143550 0.348681 0.164570 0.826294 0.606791 0.372043
BMIm 0.113546 0.203474 0.100295 0.232482 0.075666 0.250512
glicemia 1.000000 0.180464 0.168407 0.137192 0.044430 0.112503
Insp 0.180464 1.000000 0.160730 0.317127 0.207108 0.110209
Insm 0.168407 0.160730 1.000000 0.053793 -0.008991 0.023209
Vitap 0.137192 0.317127 0.053793 1.000000 0.735886 0.302096
Fiancp 0.044430 0.207108 -0.008991 0.735886 1.000000 -0.111144
Braccp 0.112503 0.110209 0.023209 0.302096 -0.111144 1.000000
Vitam 0.166120 0.130090 0.090381 0.189386 0.024460 0.249203
Fiancm 0.144205 0.130422 0.087998 0.281131 0.405990 -0.294208
Braccm -0.038253 0.040211 0.047060 0.101211 0.016534 0.168312
Creatinina 0.058882 0.034111 -0.028208 0.002382 -0.117294 0.041190
N_ureico -0.221679 0.003475 -0.061646 -0.005058 0.037735 0.011601
Uricemia -0.147481 -0.027787 -0.038108 0.002920 0.014362 0.018412
pcr 0.188429 0.109138 0.063992 0.103573 -0.007414 0.045652
Cronbachs Alpha = 0.030471 Standardized Cronbachs Alpha = 0.808706
Correlation Report
Page/Date/Time 6 2/26/2013 4:00:20 PM
Database
Controlled For: GroupHT1
Pearson Correlations Section (Pair-Wise Deletion)
Vitam Fiancm Braccm Creatinina N_ureico Uricemia
Sex -0.011343 -0.019051 0.036608 -0.025938 -0.122313 -0.080362
Eta -0.030777 -0.041695 -0.028994 0.083354 0.001515 -0.017026
BMI 0.280004 0.207955 0.128263 0.057896 0.010298 0.031626
Ins 0.211330 0.092140 0.065465 0.040684 0.025139 0.003284
kg 0.192611 0.114000 0.078723 0.114036 0.018425 0.014466
h 0.030466 0.002375 -0.004962 0.115711 0.018582 -0.001761
cv_h 0.322277 0.183345 0.200108 -0.017222 -0.028044 0.016582
Vita 0.288668 0.158191 0.155801 0.063525 -0.004883 0.009766
Fianc 0.276042 0.178542 0.154530 0.076187 0.015422 0.018389
Bracc 0.255336 0.187393 0.133491 0.066843 0.049644 0.054760
PAS 0.085162 0.081457 0.050083 0.001793 -0.014354 0.053085
PAD -0.039316 0.026491 -0.110585 -0.000971 0.050603 0.113152
PASp -0.054984 -0.048050 -0.006462 -0.056350 0.031005 0.069554
PADp 0.048409 0.011604 0.020901 0.006431 0.093739 0.140649
PASm 0.042924 0.084410 0.073915 0.136534 -0.074356 0.014024
PADm 0.010793 0.012109 0.003907 0.116763 -0.044916 -0.021319
CT -0.038860 -0.025437 -0.010177 -0.086789 0.033399 0.029193
HC 0.011771 0.017844 0.059625 -0.115678 -0.012238 0.035195
HDL -0.131746 -0.022032 -0.041815 -0.035167 -0.028980 -0.041033
nHDL 0.003523 -0.018563 0.003292 -0.076376 0.043253 0.042887
TG 0.115608 -0.039930 0.060664 0.072212 -0.024371 0.006179
LDL -0.018862 -0.012133 -0.009202 -0.088441 0.045915 0.043722
BMIp 0.221186 0.226547 0.108393 -0.033064 0.018357 0.027917
BMIm 0.741521 0.543679 0.422965 -0.008037 0.015087 -0.006816
glicemia 0.166120 0.144205 -0.038253 0.058882 -0.221679 -0.147481
Insp 0.130090 0.130422 0.040211 0.034111 0.003475 -0.027787
Insm 0.090381 0.087998 0.047060 -0.028208 -0.061646 -0.038108
Vitap 0.189386 0.281131 0.101211 0.002382 -0.005058 0.002920
Fiancp 0.024460 0.405990 0.016534 -0.117294 0.037735 0.014362
Braccp 0.249203 -0.294208 0.168312 0.041190 0.011601 0.018412
Vitam 1.000000 0.590047 0.401064 -0.035936 0.021062 -0.002221
Fiancm 0.590047 1.000000 0.289072 -0.100407 -0.006203 0.000808
Braccm 0.401064 0.289072 1.000000 -0.123682 -0.011046 -0.039252
Creatinina -0.035936 -0.100407 -0.123682 1.000000 -0.051205 0.046388
N_ureico 0.021062 -0.006203 -0.011046 -0.051205 1.000000 0.545930
Uricemia -0.002221 0.000808 -0.039252 0.046388 0.545930 1.000000
pcr 0.081120 0.030485 -0.039732 0.018435 -0.001377 -0.075539
Cronbachs Alpha = 0.030471 Standardized Cronbachs Alpha = 0.808706
Correlation Report
Page/Date/Time 7 2/26/2013 4:00:21 PM
Database
Controlled For: GroupHT1
Pearson Correlations Section (Pair-Wise Deletion)
pcr
Sex 0.022458
Eta -0.056677
BMI 0.155275
Ins 0.072354
kg 0.039485
h -0.060574
cv_h 0.160999
Vita 0.084855
Fianc 0.066999
Bracc 0.094400
PAS 0.054305
PAD -0.046967
PASp 0.055561
PADp 0.048124
PASm 0.041125
PADm -0.010039
CT 0.050185
HC 0.045257
HDL -0.144479
nHDL 0.097765
TG 0.023771
LDL 0.098360
BMIp 0.126679
BMIm 0.100814
glicemia 0.188429
Insp 0.109138
Insm 0.063992
Vitap 0.103573
Fiancp -0.007414
Braccp 0.045652
Vitam 0.081120
Fiancm 0.030485
Braccm -0.039732
Creatinina 0.018435
N_ureico -0.001377
Uricemia -0.075539
pcr 1.000000
Cronbachs Alpha = 0.030471 Standardized Cronbachs Alpha = 0.808706
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