Authors: Bo Xue Taner Z Sen Pascal Schlapfer Seung Yon Rhee An online versi on the right, a Mary L Schaeffer Peifen Zhang Periplasmic (wh CornCyc: Zea mays mays Cellular Overview Connections bet Jack M Gardiner an an an electron- electron- electron- UQ UQ UQ UQ UQ UQ UQ UQ UQ UQ UQ UQ UQ UQ UQ UQ UQ UQ UQ UQ UQ UQ UQ UQ UQ UQ a plastoquinol a plastoquinol transfer transfer transfer + 2+ quinone quinone quinone cys cys (indol- + 2+ 2+ 2+ 2+ 2+ 2+ 2+ + + L-citrulline 2+ 2+ + + 2+ Cu 2+ 2+ 2+ Cd 2+ 2+ 2+ 2+ β 2+ 2+ 2+ 2+ 2+ glutathione glutathione 3-yl) 2+ K heme b a ferric a ferric heme b a ferric Cu Cu 2+ 2+ Zn Zn Zn a -D Ca Cu heme b heme b Cu2+ Cu2+ a ferric a ferric Cu2+ a ferric a ferric Cu a xenobiotic 2+ L-ornithine 2+ an Fe(III)- sn- selenate 3+ 3+ β-D-galactofuranose a phospholipid acetate Cu2+ Cu Cu2+ Cu2+ Cu2+ Zn an (aminoalkyl)phosphonate Cu2+ Ca2+ Cu2+ Cu2+ glucan a quaternary Cu2+ Cu2+ Ca2+ Cu2+ Ca 2+ an (aminoalkyl)phosphonate an Fe(III)- an Fe(III)- an Fe(III)- an Fe(III)- an Fe(III)- an Fe(III)- an Fe(III)- an Fe(III)- glycerol Ca hydroxamate hydroxamate hydroxamate Mg Zn aldehydo-L- a monosaccharide a monosaccharide aldehydo-L- Cu2+ Cu2+ hydroxamate a monosaccharide hydroxamate Cu2+ hydroxamate hydroxamate Cd Fe siderophore selenite Fe Fe α-D-galactofuranose Cu Cu Cu Cu complex complex complex an alkylphosphonate Cu Ca Cu Cu galactonate galactonate amine Cu Cu Ca Cu Cu Mn Cu complex complex an alkylphosphonate Cu complex complex siderophore siderophore siderophore siderophore siderophore siderophore siderophore siderophore 3-phosphate thiosulfate D-galactopyranose Fe(III)-PS Zm00001d046260 Zm00001d040819 Zm00001d034244 Zm00001d025423 GRMZM5G800980 Zm00001d033530 Zm00001d038441 Zm00001d011732 Zm00001d043619 Zm00001d047441 Zm00001d021958 Zm00001d038658 Zm00001d033531 GRMZM5G866223 GRMZM5G876913 Zm00001d006714 Zm00001d042061 Zm00001d011845 GRMZM5G839924 Zm00001d013156 Zm00001d043620 GRMZM5G856027 Zm00001d033753 Zm00001d013424 Zm00001d012438 Zm00001d042953 Zm00001d022341 Zm00001d007048 PIN1 Zm00001d026253 Zm00001d003861 Zm00001d041824 Zm00001d002204 Zm00001d023701 Zm00001d015829 Zm00001d027884 Zm00001d023851 Zm00001d048946 Zm00001d014669 Zm00001d034940 Zm00001d003354 Zm00001d002224 Zm00001d046277 Zm00001d010426 Zm00001d018283 Zm00001d031340 Zm00001d043553 Zm00001d018974 Zm00001d002708 Zm00001d002705 Zm00001d010324 Zm00001d040966 Zm00001d028266 Zm00001d018500 Zm00001d005189 Zm00001d005190 Zm00001d019226 Zm00001d053603 Zm00001d021153 Zm00001d020279 Zm00001d031341 Zm00001d016395 Zm00001d038493 Zm00001d048015 Zm00001d002216 Zm00001d019403 Zm00001d023258 Zm00001d026352 Zm00001d033257 Zm00001d047207 Zm00001d033886 Zm00001d022188 Zm00001d025012 Zm00001d004505 Zm00001d009037 Zm00001d032601 Zm00001d052801 Zm00001d044442 Zm00001d011315 Zm00001d016134 Zm00001d053783 Zm00001d046662 Zm00001d004008 Zm00001d008974 Zm00001d013570 Zm00001d017429 Zm00001d003354 Zm00001d025012 Zm00001d044442 Zm00001d011315 Zm00001d009037 Zm00001d034940 Zm00001d046277 transporter Zm00001d026156 Zm00001d046068 Zm00001d019398 Zm00001d024497 Zm00001d047583 Zm00001d011845 Zm00001d042061 Zm00001d047441 Zm00001d025156 + 2+ + 2+ 2+ 2+ 2+ 2+ β 2+ 2+ + (indol- 2+ 2+ a -D + + + 2+ Cu 2+ 2+ 2+ Cd 2+ 2+ 2+ 2+ 2+ 2+ 2+ 2+ 2+ cys cys 3-yl) 2+ K heme b heme b Cu Cu 2+ 2+ Zn Zn Zn glucan Ca Cu heme b heme b 2+ 2+ 2+ Cu a xenobiotic 2+ L-citrulline 2+ 3+ 3+ β a phospholipid 2+ Cu 2+ 2+ 2+ Zn a ferric a ferric a ferric 2+ 2+ 2+ 2+ aldehydo-L- aldehydo-L- 2+ 2+ 2+ 2+ Cu 2+ Cu a ferric a ferric Cu a ferric a ferric sn- selenate -D-galactofuranose glutathione glutathione acetate 2 Cu Cu Cu Cu an (aminoalkyl)phosphonate Cu Ca Cu Cu a monosaccharide a monosaccharide a quaternary Cu Cu Ca Cu Ca a monosaccharide an (aminoalkyl)phosphonate L-ornithine an Fe(III)- an Fe(III)- an Fe(III)- an Fe(III)- an Fe(III)- an Fe(III)- an Fe(III)- an Fe(III)- α NADH NADH NADH NADH NADH NADH NADH NADH NADH NADH NADH NADH NADH NADH NADH NADH NADH NADH NADH NADH NADH NADH NADH NADH NADH NADH Ca O Cu Cu Cu Cu hydroxamate hydroxamate hydroxamate an alkylphosphonate Cu Ca Cu Cu Mg Zn galactonate galactonate amine Cu Cu Ca Cu Cu2+ Mn Cu2+ hydroxamate hydroxamate an alkylphosphonate Cu2+ hydroxamate hydroxamate an oxidized Cd Fe siderophore siderophore siderophore siderophore siderophore siderophore siderophore siderophore an Fe(III)- glycerol selenite Fe Fe -D-galactofuranose + + + + + + + + + + + + + + + + + + + + + + + + + + complex complex complex Cu Cu complex complex Cu complex complex plastocyanin siderophore thiosulfate D-galactopyranose NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 NAD UQH2 hν hν a reduced 3-phosphate a plastoquinoneplastocyanin + + + NAD(P) NAD(P) NAD(P) DEGRADATION/ COFACTORS, PROSTHETIC GROUPS, ELECTRON CARRIERS BIOSYNTHESIS oxygenic photosynthesis eumelanin biosynthesis PHOTOSYNTHESIS Rubisco shunt UTILIZATION/ OTHER BIOSYNTHESIS ASSIMILATION - OTHER α α UDP-4-dehydro-6- α UDP-β-L- 3 9 α 2+ L-ascorbate CARBOXYLATES DEGRADATION a 1,4- - a sugar -D- dCMP dCTP α D-gluconate a 1-6- - α-D-Kdo-(2->4)-α-D- (-)-methyl UMP Glc Man a 1-6- - λ N-acetyl-9-O- hydrogenobyrinate dTDP-β-L-rhamnose UDP-α-D- a ganglioside L-dopa and degradation V glucose 6- hyaluronan xylitol starch acetylxylan deoxy- -D-glucose cyanate GSSH arabinofuranose benzylbenzoate GlcNAc2- sucrose -carrageenan Co a glycogen a pectate 4-sulfomuconolactone α-linolenate α-linolenate phospholipases D-glucan alcohol 6-phosphate D-glucan Kdo-(2->6)-lipid A jasmonate D-glucan acetylneuraminate a,c-diamide galactose GM2 superpathway of phylloquinol biosynthesis L-dopachrome FATTY ACID AND LIPIDS DEGRADATION cyanide phosphate [protein] flavin biosynthesis I phytochromobilin pyridoxal 5'-phosphate salvage II (plants) thiamine salvage IV (yeast) chlorophyll cycle 4-aminobenzoate plant sterol biosynthesis H2O unsaturated, even numbered fatty acid α-oxidation I β 3,8-divinyl-chlorophyllide superpathway of geranylgeranyl superpathway of ubiquinol-10 6-hydroxymethyl- vitamin E biosynthesis (tocotrienols) thiamine salvage II phosphopantothenate heme a sanguinarine and macarpine biosynthesis SECONDARY METABOLITES BIOSYNTHESIS L-dopachrome biosynthesis F6P fatty acid beta- triacylglycerol β degradation nucleoside UDP- -L- Zm00001d018277_T002.1: λ α β a biosynthesis I diphosphate biosynthesis II (via MEP) (bacteria and plants) biosynthesis dihydropterin vitamin E biosynthesis (tocopherols) biosynthesis NUCLEOSIDES AND NUCLEOTIDES BIOSYNTHESIS plant sterol dhurrin biosynthesis superpathway of lipid-dependent phytate biosynthesis scopolin spermidine hydroxycinnamic acid conjugates biosynthesis salvigenin biosynthesis sesamin biosynthesis traumatin and (Z)-3-hexen-1-yl acetate biosynthesis salidroside pinobanksin biosynthesis (3R)-linalool lactucaxanthin 9-lipoxygenase and 9- sakuranetin degradation fatty acid -oxidation α Aldehyde dCMP deaminase: triphosphate Aldehyde starch acetylxylan UDP-L-rhamnose cyanate 6-phosphogluconate Isoamylase: Persulfide arabinose mutase: 3-deoxy-D-manno- carboxylesterase: Carboxylesterase: Dextransucrase: -carrageenase: Sialate O- Glucan 1,4-alpha- exo-poly- -D- 4-sulfomuconolactone Zm00001d017601_T001.1: ganglioside GM2 -1,3- Zm00001d030674_T001.1: geranylgeranyldiphosphate biosynthesis biosynthesis I biosynthesis phosphatidylinositol oxidation V L-ascorbate -amylase: reductase: phosphoglucose reductase: synthase: Zm00001d038121 Zm00001d018277 mannosyl- Zm00001d034701 cobaltochelatase: glucosidase: galacturonosidase: galactosyltransferase: (aerobic, light-dependent) (eukaryotic) diphosphate biosynthesis I biosynthesis II biosynthesis biosynthesis biosynthesis biosynthesis hydroperoxide lyase pathway biosynthesis 4,5-bisphosphate (unsaturated, a 2,3,4- Zm00001d005890 isomerase: hyaluronidase: Zm00001d012671 phosphatase: glucanohydrolase: esterase: hydratase: phosphatase: dioxygenase: Zm00001d014000 octulosonate Zm00001d020732 Zm00001d043235 oligosaccharide Zm00001d034477 acetylesterase: Zm00001d038475 hydrolase: Zm00001d017601 Zm00001d030674 chorismate biosynthesis I (2E,6E)- a 2-trans hydrogen Zm00001d010054 Zm00001d021726 Zm00001d042869 Zm00001d024890 Zm00001d017601 Zm00001d032736 [+ 11 isozymes] Zm00001d043941 hydrolase: [+ 2 isozymes] Zm00001d034901 Zm00001d038304 Zm00001d020931 Zm00001d025249 Zm00001d037233 (via mevalonate) pyridoxal thiamine 4-amino-2-methyl-5- chlorophyllide a tyr photosystem II: lipase C: Zm00001d014906 odd number, saturated Zm00001d020771 Zm00001d022425 Zm00001d005890 Zm00001d043291 [+ 95 isozymes] [+ 2 isozymes] glucosidase: [+ 3 isozymes] D-glyceraldehyde ferroheme b homogentisate GGPP 3-methyl-2- a 5,10-methylene- chorismate farnesyl (S)-reticuline D-myo-inositol flavonoid biosynthesis (in equisetum) 4-coumaroyl- (2S)- coniferyl α L-dopachrome a 1- -4-cis- L-ascorbate cyanide [+ 6 isozymes] [+ 10 isozymes] Zm00001d006481 Zm00001d042335 α λ λ pyruvate superpathay of folate transformations II 4-hydroxyphenylpyruvate pyrimidinemethanol ferroheme b superpathway of purine (1,3,4)- Ins(1,4,5)P3 linoleate -linolenate (E)-cinnamoyl-CoA Zm00001d010715 di-isomerase- a triglyceride fatty acid [+ 5 isozymes] [+ 5 isozymes] [+ 6 isozymes] [+ 2 isozymes] a 1-6- - neo- - neo- - cob(II) isochorismate uroporphyrinogen-III 3-phosphate GTP (2E,6E)-farnesyl oxobutanoate tetrahydrofolate chlorophyllide-a nucleotides de novo biosynthesis I superpathway of pyrimidine deoxyribonucleotides superpathway of pyrimidine